locus-tag	class	description
FY143_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY143_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY143_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY143_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY143_00025	COG1420	regulation of RNA biosynthetic process
FY143_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY143_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY143_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY143_00050	COG1137	ATPase activity
FY143_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY143_00065	COG0616	signal peptide processing
FY143_00070	COG0776	regulation of translation
FY143_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY143_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY143_00095	COG5002	protein histidine kinase activity
FY143_00095	COG0784	Response regulator, receiver
FY143_00095	COG2205	protein histidine kinase activity
FY143_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY143_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY143_00115	COG0728	peptidoglycan biosynthetic process
FY143_00125	COG0180	Tryptophanyl-tRNA synthetase
FY143_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY143_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY143_00145	COG0456	acetyltransferase
FY143_00145	COG1214	PFAM Peptidase M22, glycoprotease
FY143_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY143_00165	COG1702	phosphate starvation-inducible protein PhoH
FY143_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY143_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY143_00185	COG1396	sequence-specific DNA binding
FY143_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY143_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY143_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_00210	COG0242	peptide deformylase activity
FY143_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY143_00220	COG0101	tRNA pseudouridine synthase activity
FY143_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY143_00235	COG2171	N-acyltransferase activity
FY143_00245	COG0840	transmembrane signaling receptor activity
FY143_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY143_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY143_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY143_00295	COG0706	membrane insertase activity
FY143_00300	COG0594	ribonuclease P activity
FY143_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY143_00310	COG0840	transmembrane signaling receptor activity
FY143_00325	COG2226	methyltransferase
FY143_00330	COG3842	ATPase activity
FY143_00335	COG1175	transmembrane transport
FY143_00340	COG0395	ABC-type sugar transport system, permease component
FY143_00355	COG0427	acetyl-CoA hydrolase
FY143_00365	COG3938	Belongs to the proline racemase family
FY143_00370	COG0418	dihydroorotase activity
FY143_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY143_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY143_00400	COG0166	Belongs to the GPI family
FY143_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY143_00410	COG3842	ATPase activity
FY143_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY143_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY143_00425	COG4774	siderophore transport
FY143_00465	COG2326	polyphosphate kinase activity
FY143_00470	COG5002	protein histidine kinase activity
FY143_00475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY143_00480	COG0573	inorganic phosphate transmembrane transporter activity
FY143_00490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY143_00495	COG0704	Plays a role in the regulation of phosphate uptake
FY143_00500	COG0745	RESPONSE REGULATOR receiver
FY143_00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY143_00515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY143_00525	COG2967	ApaG domain
FY143_00540	COG0717	Belongs to the dCTP deaminase family
FY143_00550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY143_00600	COG0167	dihydroorotate dehydrogenase activity
FY143_00615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY143_00635	COG1959	2 iron, 2 sulfur cluster binding
FY143_00640	COG1201	RNA secondary structure unwinding
FY143_00670	COG1960	acyl-CoA dehydrogenase activity
FY143_00675	COG0183	Belongs to the thiolase family
FY143_00680	COG1024	Enoyl-CoA hydratase
FY143_00680	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY143_00720	COG1320	monovalent cation:proton antiporter activity
FY143_00725	COG2212	antiporter activity
FY143_00730	COG1863	multisubunit Na H antiporter MnhE subunit
FY143_00735	COG0651	ATP synthesis coupled electron transport
FY143_00740	COG1006	Multisubunit Na H antiporter MnhC subunit
FY143_00745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY143_00745	COG2111	Na H antiporter
FY143_00755	COG0840	transmembrane signaling receptor activity
FY143_00765	COG0745	RESPONSE REGULATOR receiver
FY143_00770	COG0643	Histidine kinase
FY143_00770	COG2198	Histidine kinase
FY143_00775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY143_00780	COG2201	protein-glutamate methylesterase activity
FY143_00785	COG0745	RESPONSE REGULATOR receiver
FY143_00790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY143_00800	COG1766	The M ring may be actively involved in energy transduction
FY143_00805	COG2771	luxR family
FY143_00815	COG0840	transmembrane signaling receptor activity
FY143_00815	COG2972	Histidine kinase
FY143_00820	COG0784	Response regulator, receiver
FY143_00820	COG2198	Histidine kinase
FY143_00820	COG2205	protein histidine kinase activity
FY143_00825	COG1970	mechanosensitive ion channel activity
FY143_00830	COG0436	Aminotransferase
FY143_00845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY143_00850	COG0424	maF-like protein
FY143_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY143_00865	COG5328	Belongs to the UPF0262 family
FY143_00870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY143_00880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY143_00895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY143_00910	COG1338	Plays a role in the flagellum-specific transport system
FY143_00920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY143_00930	COG1706	bacterial-type flagellum-dependent cell motility
FY143_00935	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY143_00940	COG4786	Flagellar basal body rod
FY143_00945	COG1677	Flagellar hook-basal body complex protein FliE
FY143_00950	COG1558	bacterial-type flagellum-dependent cell motility
FY143_00955	COG1815	bacterial-type flagellum-dependent cell motility
FY143_00965	COG1157	protein secretion by the type III secretion system
FY143_00970	COG4786	Flagellar basal body rod
FY143_00980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY143_00985	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY143_00990	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY143_00995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY143_01000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY143_01020	COG1360	Flagellar Motor Protein
FY143_01045	COG1749	Flagellar hook protein flgE
FY143_01065	COG5443	negative regulation of bacterial-type flagellum assembly
FY143_01070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY143_01080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY143_01120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY143_01125	COG1609	Transcriptional regulator
FY143_01130	COG1653	transport
FY143_01135	COG1175	transmembrane transport
FY143_01140	COG0395	ABC-type sugar transport system, permease component
FY143_01145	COG0366	Alpha amylase catalytic
FY143_01150	COG3842	ATPase activity
FY143_01165	COG0129	dihydroxy-acid dehydratase activity
FY143_01170	COG0363	glucosamine-6-phosphate deaminase activity
FY143_01175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY143_01185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_01195	COG2081	HI0933 family
FY143_01215	COG2224	Isocitrate lyase
FY143_01230	COG3842	ATPase activity
FY143_01235	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_01240	COG1177	transmembrane transport
FY143_01250	COG2205	protein histidine kinase activity
FY143_01260	COG0248	Ppx GppA phosphatase
FY143_01265	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY143_01270	COG0477	Major facilitator Superfamily
FY143_01300	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY143_01305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY143_01315	COG0142	geranyltranstransferase activity
FY143_01340	COG0752	glycyl-tRNA synthetase alpha subunit
FY143_01350	COG1704	LemA family
FY143_01355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY143_01365	COG0751	glycine-tRNA ligase activity
FY143_01385	COG0840	transmembrane signaling receptor activity
FY143_01395	COG0151	Belongs to the GarS family
FY143_01400	COG2183	response to ionizing radiation
FY143_01405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY143_01430	COG0583	DNA-binding transcription factor activity
FY143_01450	COG0306	phosphate transporter
FY143_01460	COG0561	phosphatase activity
FY143_01465	COG0438	transferase activity, transferring glycosyl groups
FY143_01470	COG2186	Transcriptional regulator
FY143_01480	COG0583	DNA-binding transcription factor activity
FY143_01485	COG0277	FAD linked oxidase domain protein
FY143_01490	COG0277	FAD linked oxidase domain protein
FY143_01495	COG0247	lactate metabolic process
FY143_01505	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_01510	COG2818	Glycosylase
FY143_01520	COG2855	membrane
FY143_01525	COG0583	DNA-binding transcription factor activity
FY143_01545	COG0124	histidyl-tRNA synthetase
FY143_01555	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY143_01560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY143_01565	COG2259	Doxx family
FY143_01575	COG0459	protein refolding
FY143_01580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY143_01590	COG0196	riboflavin kinase activity
FY143_01595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY143_01605	COG0590	tRNA wobble adenosine to inosine editing
FY143_01610	COG1187	pseudouridine synthase activity
FY143_01615	COG0742	ribosomal rna small subunit methyltransferase
FY143_01620	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY143_01630	COG0312	modulator of DNA gyrase
FY143_01645	COG1519	Transferase
FY143_01655	COG1663	tetraacyldisaccharide 4'-kinase activity
FY143_01665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY143_01670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_01670	COG2205	protein histidine kinase activity
FY143_01675	COG3300	MHYT domain
FY143_01675	COG5001	Diguanylate cyclase
FY143_01680	COG3386	PFAM SMP-30 Gluconolaconase
FY143_01685	COG0800	Aldolase
FY143_01690	COG3734	2-keto-3-deoxy-galactonokinase
FY143_01695	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_01705	COG2197	response regulator
FY143_01720	COG0598	Magnesium transport protein CorA
FY143_01725	COG3158	transport of potassium into the cell
FY143_01740	COG0356	it plays a direct role in the translocation of protons across the membrane
FY143_01750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY143_01755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY143_01765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY143_01785	COG0009	L-threonylcarbamoyladenylate synthase
FY143_01795	COG4638	Rieske (2fe-2S)
FY143_01820	COG1960	acyl-CoA dehydrogenase activity
FY143_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY143_01840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY143_01845	COG0840	transmembrane signaling receptor activity
FY143_01870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY143_01875	COG1741	Belongs to the pirin family
FY143_01880	COG1722	exodeoxyribonuclease VII activity
FY143_01885	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY143_01890	COG1268	BioY protein
FY143_01895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY143_01900	COG1122	ATPase activity
FY143_01905	COG3214	Protein conserved in bacteria
FY143_01910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY143_01910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY143_01915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY143_01935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY143_01940	COG0484	heat shock protein binding
FY143_01950	COG0259	pyridoxamine-phosphate oxidase activity
FY143_01965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY143_01975	COG0312	modulator of DNA gyrase
FY143_01990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY143_01995	COG0109	protoheme IX farnesyltransferase activity
FY143_02000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY143_02015	COG3346	SURF1 family
FY143_02020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY143_02025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY143_02030	COG0328	RNA-DNA hybrid ribonuclease activity
FY143_02040	COG0678	peroxiredoxin activity
FY143_02040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY143_02050	COG1678	Uncharacterized ACR, COG1678
FY143_02070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY143_02075	COG0612	Peptidase, M16
FY143_02090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY143_02110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY143_02120	COG1194	a g-specific adenine glycosylase
FY143_02130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY143_02135	COG1196	nuclear chromosome segregation
FY143_02140	COG2514	catechol 2,3-dioxygenase activity
FY143_02145	COG0574	Belongs to the PEP-utilizing enzyme family
FY143_02145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY143_02160	COG1823	symporter activity
FY143_02180	COG0579	oxidoreductase
FY143_02205	COG2895	sulfate adenylyltransferase (ATP) activity
FY143_02210	COG0175	sulfate reduction
FY143_02215	COG0175	sulfate reduction
FY143_02220	COG1959	2 iron, 2 sulfur cluster binding
FY143_02225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY143_02230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY143_02235	COG4208	sulfate ABC transporter
FY143_02240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY143_02250	COG2199	diguanylate cyclase activity
FY143_02250	COG2203	Gaf domain
FY143_02250	COG2200	EAL domain
FY143_02260	COG1309	transcriptional regulator
FY143_02265	COG1012	belongs to the aldehyde dehydrogenase family
FY143_02270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY143_02315	COG0477	Major facilitator Superfamily
FY143_02325	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY143_02325	COG1793	dna ligase
FY143_02340	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_02345	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_02360	COG1846	Transcriptional regulator
FY143_02365	COG1764	response to oxidative stress
FY143_02380	COG0488	(ABC) transporter
FY143_02415	COG0583	DNA-binding transcription factor activity
FY143_02420	COG4221	oxidoreductase activity
FY143_02430	COG0433	COG0433 Predicted ATPase
FY143_02440	COG1733	regulation of RNA biosynthetic process
FY143_02445	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY143_02455	COG1280	lysine exporter protein (LysE YggA)
FY143_02460	COG0656	L-ascorbic acid biosynthetic process
FY143_02465	COG2378	regulation of single-species biofilm formation
FY143_02475	COG4106	trans-aconitate 2-methyltransferase activity
FY143_02480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY143_02485	COG0840	transmembrane signaling receptor activity
FY143_02490	COG0583	DNA-binding transcription factor activity
FY143_02505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY143_02525	COG3909	cytochrome
FY143_02530	COG2010	Cytochrome c
FY143_02560	COG0789	Transcriptional regulator
FY143_02590	COG4176	ABC-type proline glycine betaine transport system permease component
FY143_02615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_02625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY143_02625	COG2169	Transcriptional regulator
FY143_02635	COG2514	catechol 2,3-dioxygenase activity
FY143_02655	COG1272	protein, Hemolysin III
FY143_02665	COG1280	lysine exporter protein (LysE YggA)
FY143_02670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY143_02675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY143_02675	COG2111	Na H antiporter
FY143_02680	COG2111	Na H antiporter
FY143_02685	COG1006	Multisubunit Na H antiporter MnhC subunit
FY143_02690	COG0651	ATP synthesis coupled electron transport
FY143_02695	COG1863	multisubunit Na H antiporter MnhE subunit
FY143_02700	COG2212	antiporter activity
FY143_02705	COG1320	monovalent cation:proton antiporter activity
FY143_02710	COG4957	zinc ion binding
FY143_02725	COG2166	iron-sulfur cluster assembly
FY143_02735	COG2205	protein histidine kinase activity
FY143_02790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY143_02795	COG2983	Belongs to the UPF0260 family
FY143_02825	COG1621	beta-fructofuranosidase activity
FY143_02830	COG2202	Pas domain
FY143_02830	COG3920	Histidine kinase
FY143_02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY143_02885	COG4695	Portal protein
FY143_02990	COG4235	cytochrome complex assembly
FY143_02995	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY143_03000	COG1138	Cytochrome C-type biogenesis protein
FY143_03005	COG3088	subunit of a heme lyase
FY143_03010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY143_03015	COG0745	RESPONSE REGULATOR receiver
FY143_03025	COG3011	Protein conserved in bacteria
FY143_03035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY143_03040	COG2202	Pas domain
FY143_03040	COG2205	protein histidine kinase activity
FY143_03050	COG0308	aminopeptidase N
FY143_03070	COG0443	Heat shock 70 kDa protein
FY143_03080	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_03105	COG0604	alcohol dehydrogenase
FY143_03110	COG1733	regulation of RNA biosynthetic process
FY143_03115	COG1968	undecaprenyl-diphosphatase activity
FY143_03120	COG2239	Acts as a magnesium transporter
FY143_03125	COG2814	Major facilitator Superfamily
FY143_03145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY143_03170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY143_03240	COG1802	Transcriptional regulator
FY143_03240	COG4626	Terminase
FY143_03280	COG0741	lytic transglycosylase activity
FY143_03285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_03290	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY143_03295	COG0840	transmembrane signaling receptor activity
FY143_03305	COG1758	RNA polymerase activity
FY143_03325	COG0736	holo-[acyl-carrier-protein] synthase activity
FY143_03330	COG0681	Belongs to the peptidase S26 family
FY143_03335	COG0571	ribonuclease III activity
FY143_03340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY143_03345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY143_03350	COG0784	Response regulator, receiver
FY143_03355	COG1381	Involved in DNA repair and RecF pathway recombination
FY143_03365	COG2226	methyltransferase
FY143_03375	COG1418	mRNA catabolic process
FY143_03385	COG0346	lactoylglutathione lyase activity
FY143_03400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_03405	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY143_03410	COG0668	transmembrane transport
FY143_03420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY143_03425	COG0354	folic acid binding
FY143_03450	COG1742	UPF0060 membrane protein
FY143_03465	COG1183	phosphatidylcholine synthase activity
FY143_03470	COG0688	phosphatidylethanolamine metabolic process
FY143_03475	COG5265	(ABC) transporter
FY143_03520	COG2852	Protein conserved in bacteria
FY143_03525	COG0215	cysteine-tRNA ligase activity
FY143_03530	COG4221	oxidoreductase activity
FY143_03535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY143_03540	COG1286	toxin biosynthetic process
FY143_03555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY143_03565	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY143_03575	COG0305	Participates in initiation and elongation during chromosome replication
FY143_03600	COG0359	binds to the 23S rRNA
FY143_03610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY143_03615	COG0360	Binds together with S18 to 16S ribosomal RNA
FY143_03620	COG0667	Aldo Keto reductase
FY143_03625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY143_03635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY143_03640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY143_03645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY143_03650	COG1561	YicC-like family, N-terminal region
FY143_03655	COG0194	GDP metabolic process
FY143_03665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY143_03670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY143_03680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY143_03695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY143_03720	COG0488	(ABC) transporter
FY143_03725	COG3706	GGDEF domain
FY143_03735	COG0105	UTP biosynthetic process
FY143_03755	COG0314	molybdopterin synthase activity
FY143_03765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY143_03770	COG0322	excinuclease ABC activity
FY143_03775	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_03785	COG0625	glutathione transferase activity
FY143_03800	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY143_03805	COG0243	molybdopterin cofactor binding
FY143_03820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY143_03825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY143_03830	COG0628	permease
FY143_03840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY143_03845	COG0248	Ppx GppA phosphatase
FY143_03870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY143_03880	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY143_03885	COG0477	Major facilitator Superfamily
FY143_03890	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY143_03895	COG4452	Inner membrane protein CreD
FY143_03900	COG0659	secondary active sulfate transmembrane transporter activity
FY143_03910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY143_03920	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY143_03930	COG0113	porphobilinogen synthase activity
FY143_03950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY143_03955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY143_03960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY143_03960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY143_03970	COG1280	lysine exporter protein (LysE YggA)
FY143_03975	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY143_03980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY143_03985	COG2814	Major facilitator Superfamily
FY143_03990	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY143_04010	COG0416	fatty acid biosynthetic process
FY143_04015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY143_04020	COG0776	regulation of translation
FY143_04050	COG0789	Transcriptional regulator
FY143_04055	COG0601	transmembrane transport
FY143_04060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_04065	COG0444	Belongs to the ABC transporter superfamily
FY143_04075	COG0747	negative chemotaxis
FY143_04085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY143_04090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY143_04105	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY143_04110	COG0583	DNA-binding transcription factor activity
FY143_04120	COG0737	Belongs to the 5'-nucleotidase family
FY143_04145	COG2897	thiosulfate sulfurtransferase activity
FY143_04160	COG0415	Belongs to the DNA photolyase family
FY143_04170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY143_04200	COG3932	Exopolysaccharide synthesis, ExoD
FY143_04205	COG1238	metal cluster binding
FY143_04220	COG4139	cobalamin transport
FY143_04225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY143_04235	COG1528	Iron-storage protein
FY143_04300	COG1612	heme a metabolic process
FY143_04310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY143_04315	COG0010	Belongs to the arginase family
FY143_04320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY143_04325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY143_04340	COG1832	CoA-binding protein
FY143_04360	COG2199	diguanylate cyclase activity
FY143_04365	COG0740	serine-type endopeptidase activity
FY143_04370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY143_04375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY143_04410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY143_04415	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY143_04420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY143_04430	COG0649	NAD binding
FY143_04440	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY143_04445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY143_04455	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY143_04460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY143_04470	COG0713	ATP synthesis coupled electron transport
FY143_04485	COG1007	ATP synthesis coupled electron transport
FY143_04490	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY143_04490	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY143_04505	COG0442	prolyl-tRNA aminoacylation
FY143_04515	COG1136	(ABC) transporter
FY143_04530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY143_04540	COG0784	Response regulator, receiver
FY143_04550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY143_04555	COG0477	Major facilitator Superfamily
FY143_04570	COG0557	exoribonuclease II activity
FY143_04575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY143_04590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY143_04600	COG0540	Belongs to the ATCase OTCase family
FY143_04605	COG1960	acyl-CoA dehydrogenase activity
FY143_04610	COG0456	acetyltransferase
FY143_04630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY143_04635	COG2824	Alkylphosphonate utilization operon protein PhnA
FY143_04640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY143_04645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY143_04650	COG0154	amidase activity
FY143_04655	COG3811	Belongs to the UPF0386 family
FY143_04670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY143_04680	COG0456	acetyltransferase
FY143_04695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY143_04705	COG0511	ligase activity, forming carbon-carbon bonds
FY143_04710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY143_04720	COG0436	Aminotransferase
FY143_04740	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_04745	COG1530	ribonuclease E activity
FY143_04755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY143_04775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY143_04780	COG0384	phenazine biosynthesis protein PhzF
FY143_04795	COG0633	Ferredoxin
FY143_04810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY143_04815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY143_04825	COG3768	UPF0283 membrane protein
FY143_04830	COG3106	COG3106 Predicted ATPase
FY143_04860	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY143_04895	COG0537	adenosine 5'-monophosphoramidase activity
FY143_04920	COG0052	Belongs to the universal ribosomal protein uS2 family
FY143_04925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY143_04930	COG0528	UMP kinase activity
FY143_04935	COG0233	cytoplasmic translational termination
FY143_04940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY143_04950	COG0750	zinc metalloprotease
FY143_04955	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY143_04960	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY143_04965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY143_04970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY143_04975	COG3494	Protein of unknown function (DUF1009)
FY143_04980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY143_04985	COG0372	Belongs to the citrate synthase family
FY143_05000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY143_05010	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY143_05015	COG0148	phosphopyruvate hydratase activity
FY143_05025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY143_05030	COG0022	dehydrogenase e1 component
FY143_05030	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY143_05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY143_05045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY143_05055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY143_05060	COG0697	spore germination
FY143_05075	COG2867	negative regulation of translational initiation
FY143_05085	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY143_05085	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY143_05095	COG3852	Histidine kinase
FY143_05100	COG2204	response regulator
FY143_05105	COG5000	phosphorelay sensor kinase activity
FY143_05110	COG2204	response regulator
FY143_05115	COG0569	domain protein
FY143_05120	COG1923	regulation of RNA biosynthetic process
FY143_05125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY143_05130	COG3956	TIGRFAM MazG family protein
FY143_05140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY143_05140	COG1648	precorrin-2 dehydrogenase activity
FY143_05180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY143_05180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY143_05185	COG0509	glycine decarboxylation via glycine cleavage system
FY143_05190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY143_05220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY143_05225	COG0564	pseudouridine synthase activity
FY143_05230	COG0546	phosphoglycolate phosphatase activity
FY143_05260	COG1671	Belongs to the UPF0178 family
FY143_05270	COG0450	alkyl hydroperoxide reductase
FY143_05275	COG0625	glutathione transferase activity
FY143_05315	COG2801	Transposase and inactivated derivatives
FY143_05325	COG0583	DNA-binding transcription factor activity
FY143_05330	COG2828	Protein conserved in bacteria
FY143_05345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_05350	COG0784	Response regulator, receiver
FY143_05350	COG4191	Histidine kinase
FY143_05355	COG0784	Response regulator, receiver
FY143_05360	COG3920	Histidine kinase
FY143_05360	COG2202	Pas domain
FY143_05365	COG4191	Histidine kinase
FY143_05365	COG0784	Response regulator, receiver
FY143_05395	COG0673	inositol 2-dehydrogenase activity
FY143_05405	COG1609	Transcriptional regulator
FY143_05410	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_05415	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_05420	COG1129	ABC transporter
FY143_05425	COG1879	ABC-type sugar transport system periplasmic component
FY143_05430	COG0328	RNA-DNA hybrid ribonuclease activity
FY143_05440	COG2226	methyltransferase
FY143_05450	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY143_05450	COG0321	lipoyl(octanoyl) transferase activity
FY143_05455	COG0084	hydrolase, TatD family'
FY143_05460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY143_05470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY143_05495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY143_05505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY143_05555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY143_05560	COG2095	MarC family integral membrane protein
FY143_05565	COG0517	IMP dehydrogenase activity
FY143_05565	COG0617	tRNA 3'-terminal CCA addition
FY143_05565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY143_05570	COG0629	single-stranded DNA binding
FY143_05575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY143_05585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY143_05595	COG3685	Protein conserved in bacteria
FY143_05600	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY143_05615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY143_05620	COG1121	(ABC) transporter
FY143_05640	COG0667	Aldo Keto reductase
FY143_05650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY143_05725	COG2239	Acts as a magnesium transporter
FY143_05730	COG0243	molybdopterin cofactor binding
FY143_05740	COG0242	peptide deformylase activity
FY143_05760	COG0321	lipoyl(octanoyl) transferase activity
FY143_05765	COG1064	alcohol dehydrogenase
FY143_05795	COG1862	Preprotein translocase
FY143_05815	COG2124	cytochrome p450
FY143_05830	COG0596	Alpha beta hydrolase
FY143_05840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY143_05845	COG0626	cystathionine gamma-synthase activity
FY143_05850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_05855	COG4597	amino acid ABC transporter
FY143_05860	COG0765	amino acid transport
FY143_05865	COG1126	abc transporter atp-binding protein
FY143_05880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY143_05895	COG0436	Aminotransferase
FY143_05925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY143_05940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY143_05945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY143_05950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY143_05965	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY143_05970	COG1489	DNA binding
FY143_05975	COG0024	Methionine aminopeptidase
FY143_05980	COG2003	Belongs to the UPF0758 family
FY143_05995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY143_06010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY143_06015	COG0546	phosphoglycolate phosphatase activity
FY143_06030	COG0114	fumarate hydratase activity
FY143_06040	COG0504	CTP synthase activity
FY143_06050	COG0149	triose-phosphate isomerase activity
FY143_06060	COG0187	DNA topoisomerase II activity
FY143_06065	COG0740	serine-type endopeptidase activity
FY143_06075	COG0640	Transcriptional regulator
FY143_06080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY143_06085	COG0745	RESPONSE REGULATOR receiver
FY143_06100	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY143_06100	COG3264	Mechanosensitive ion channel
FY143_06165	COG1127	ABC transporter
FY143_06170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY143_06175	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_06185	COG0280	phosphate acetyltransferase
FY143_06185	COG0281	malic enzyme
FY143_06195	COG0778	Nitroreductase
FY143_06200	COG0823	Involved in the tonB-independent uptake of proteins
FY143_06215	COG1368	sulfuric ester hydrolase activity
FY143_06245	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY143_06265	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY143_06285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY143_06310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY143_06310	COG0512	Glutamine amidotransferase of anthranilate synthase
FY143_06315	COG0343	queuine tRNA-ribosyltransferase activity
FY143_06320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY143_06335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY143_06350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY143_06355	COG0134	indole-3-glycerol-phosphate synthase activity
FY143_06360	COG0315	cyclic pyranopterin monophosphate synthase activity
FY143_06365	COG0303	'Molybdopterin
FY143_06370	COG3706	GGDEF domain
FY143_06380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY143_06380	COG0475	glutathione-regulated potassium exporter activity
FY143_06390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY143_06395	COG0697	spore germination
FY143_06400	COG2814	Major facilitator Superfamily
FY143_06405	COG0746	molybdenum cofactor guanylyltransferase activity
FY143_06410	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY143_06415	COG0739	heme binding
FY143_06420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY143_06425	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY143_06430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY143_06435	COG0805	protein transport
FY143_06440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY143_06445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY143_06450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY143_06455	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY143_06460	COG1472	Belongs to the glycosyl hydrolase 3 family
FY143_06470	COG0018	arginyl-trna synthetase
FY143_06475	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY143_06480	COG0316	Belongs to the HesB IscA family
FY143_06505	COG0525	valine-tRNA ligase activity
FY143_06515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY143_06540	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY143_06545	COG1546	Belongs to the CinA family
FY143_06545	COG1058	Belongs to the CinA family
FY143_06550	COG0589	response to stress
FY143_06555	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY143_06565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY143_06580	COG1914	H( )-stimulated, divalent metal cation uptake system
FY143_06590	COG1132	(ABC) transporter
FY143_06595	COG0628	permease
FY143_06630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY143_06640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY143_06650	COG0302	gtp cyclohydrolase
FY143_06655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY143_06660	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY143_06665	COG0516	GMP reductase activity
FY143_06665	COG0517	IMP dehydrogenase activity
FY143_06695	COG1760	l-serine dehydratase
FY143_06730	COG0583	DNA-binding transcription factor activity
FY143_06745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY143_06745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY143_06750	COG0347	Belongs to the P(II) protein family
FY143_06755	COG0174	glutamine synthetase
FY143_06785	COG0697	spore germination
FY143_06795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY143_06805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY143_06835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY143_06840	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY143_06845	COG2186	Transcriptional regulator
FY143_06855	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY143_06860	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY143_06865	COG3845	ABC transporter
FY143_06870	COG1183	phosphatidylcholine synthase activity
FY143_06875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY143_06880	COG0679	Auxin Efflux Carrier
FY143_06885	COG0785	Cytochrome C biogenesis protein
FY143_06920	COG0346	lactoylglutathione lyase activity
FY143_06925	COG1278	Cold shock
FY143_06990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY143_07045	COG1136	(ABC) transporter
FY143_07045	COG0577	efflux transmembrane transporter activity
FY143_07050	COG1136	(ABC) transporter
FY143_07050	COG0577	efflux transmembrane transporter activity
FY143_07065	COG2151	metal-sulfur cluster biosynthetic enzyme
FY143_07070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY143_07075	COG0719	Fe-S assembly protein
FY143_07080	COG0396	ATPase activity
FY143_07085	COG0719	Fe-S assembly protein
FY143_07090	COG1104	cysteine desulfurase activity
FY143_07095	COG2945	thiolester hydrolase activity
FY143_07100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY143_07105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY143_07115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY143_07120	COG2833	Protein of unknown function (DUF455)
FY143_07125	COG0739	heme binding
FY143_07130	COG0513	Belongs to the DEAD box helicase family
FY143_07155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY143_07165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY143_07170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY143_07175	COG0047	phosphoribosylformylglycinamidine synthase activity
FY143_07190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY143_07200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY143_07220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY143_07225	COG2814	Major facilitator Superfamily
FY143_07230	COG0483	inositol monophosphate 1-phosphatase activity
FY143_07235	COG0483	inositol monophosphate 1-phosphatase activity
FY143_07240	COG0037	tRNA processing
FY143_07245	COG2066	Belongs to the glutaminase family
FY143_07250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY143_07255	COG0861	Integral membrane protein TerC family
FY143_07275	COG1280	lysine exporter protein (LysE YggA)
FY143_07285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY143_07290	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY143_07300	COG0538	isocitrate dehydrogenase activity
FY143_07315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY143_07320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY143_07325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_07330	COG2313	pseudouridylate synthase activity
FY143_07340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_07345	COG4215	(ABC) transporter
FY143_07355	COG5425	PFAM Usg family protein
FY143_07365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY143_07370	COG1522	sequence-specific DNA binding
FY143_07375	COG1573	uracil-dna glycosylase
FY143_07385	COG2202	Pas domain
FY143_07385	COG2205	protein histidine kinase activity
FY143_07395	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY143_07400	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY143_07415	COG0842	Transport permease protein
FY143_07420	COG1131	(ABC) transporter
FY143_07425	COG0730	response to heat
FY143_07435	COG0840	transmembrane signaling receptor activity
FY143_07435	COG0840	transmembrane signaling receptor activity
FY143_07445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY143_07450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY143_07465	COG0129	dihydroxy-acid dehydratase activity
FY143_07470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY143_07475	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY143_07485	COG3739	integral membrane protein
FY143_07495	COG0203	ribosomal protein L17
FY143_07500	COG0202	RNA polymerase activity
FY143_07505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY143_07510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY143_07515	COG0563	adenylate kinase activity
FY143_07520	COG0201	protein transport
FY143_07525	COG0200	Binds to the 23S rRNA
FY143_07530	COG1841	ribosomal large subunit assembly
FY143_07535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY143_07540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY143_07545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY143_07550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY143_07555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY143_07560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY143_07565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY143_07570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY143_07575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY143_07580	COG0255	Belongs to the universal ribosomal protein uL29 family
FY143_07585	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY143_07590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY143_07595	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY143_07600	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY143_07605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY143_07610	COG0089	rRNA binding
FY143_07615	COG0088	Forms part of the polypeptide exit tunnel
FY143_07620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY143_07625	COG0051	transcription antitermination factor activity, RNA binding
FY143_07630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY143_07635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY143_07640	COG0049	tRNA binding
FY143_07645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY143_07660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY143_07665	COG0085	RNA polymerase activity
FY143_07675	COG0222	ribosome binding
FY143_07680	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY143_07685	COG0081	regulation of translation
FY143_07690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY143_07700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY143_07715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY143_07720	COG0861	Integral membrane protein TerC family
FY143_07750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY143_07755	COG1607	acyl-coa hydrolase
FY143_07780	COG2910	NAD(P)H-binding
FY143_07785	COG1733	regulation of RNA biosynthetic process
FY143_07795	COG0556	nucleotide-excision repair
FY143_07800	COG2382	esterase
FY143_07820	COG0484	heat shock protein binding
FY143_07830	COG0582	viral genome integration into host DNA
FY143_07945	COG3842	ATPase activity
FY143_07955	COG1840	ABC-type Fe3 transport system, periplasmic component
FY143_07960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY143_07975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY143_07985	COG2207	Transcriptional regulator
FY143_07990	COG1064	alcohol dehydrogenase
FY143_07995	COG1252	NADH dehydrogenase
FY143_08000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY143_08005	COG2197	response regulator
FY143_08010	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY143_08015	COG1090	epimerase
FY143_08055	COG0656	L-ascorbic acid biosynthetic process
FY143_08070	COG0440	acetolactate synthase activity
FY143_08075	COG0028	Belongs to the TPP enzyme family
FY143_08085	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY143_08090	COG0560	Phosphoserine phosphatase
FY143_08090	COG3830	Belongs to the UPF0237 family
FY143_08110	COG0330	HflC and HflK could
FY143_08115	COG0330	HflC and HflK could
FY143_08125	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY143_08165	COG0277	FAD linked oxidase domain protein
FY143_08170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY143_08225	COG1335	isochorismatase
FY143_08245	COG0006	proline dipeptidase activity
FY143_08250	COG2264	protein methyltransferase activity
FY143_08255	COG1999	signal sequence binding
FY143_08265	COG0835	chemotaxis
FY143_08275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY143_08280	COG0583	DNA-binding transcription factor activity
FY143_08290	COG1247	-acetyltransferase
FY143_08300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY143_08315	COG0497	DNA recombination
FY143_08320	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY143_08330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY143_08335	COG0849	cell division
FY143_08340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY143_08345	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY143_08350	COG0477	Major facilitator Superfamily
FY143_08360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY143_08365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY143_08370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY143_08380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY143_08385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY143_08395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY143_08410	COG0275	rRNA processing
FY143_08415	COG2001	Belongs to the MraZ family
FY143_08440	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY143_08470	COG4106	trans-aconitate 2-methyltransferase activity
FY143_08490	COG2226	methyltransferase
FY143_08500	COG2267	carboxylic ester hydrolase activity
FY143_08505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY143_08520	COG0251	oxidation-reduction process
FY143_08535	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_08565	COG1012	belongs to the aldehyde dehydrogenase family
FY143_08570	COG0174	glutamine synthetase
FY143_08575	COG0531	amino acid
FY143_08585	COG1737	Transcriptional regulator
FY143_08590	COG1840	ABC-type Fe3 transport system, periplasmic component
FY143_08605	COG3842	ATPase activity
FY143_08665	COG2968	Membrane
FY143_08675	COG0432	Pfam Uncharacterised protein family UPF0047
FY143_08690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY143_08695	COG0358	DNA primase activity
FY143_08705	COG0505	Belongs to the CarA family
FY143_08710	COG0534	Mate efflux family protein
FY143_08725	COG2321	neutral zinc metallopeptidase
FY143_08740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY143_08745	COG3706	GGDEF domain
FY143_08750	COG1573	uracil-dna glycosylase
FY143_08760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY143_08770	COG1522	sequence-specific DNA binding
FY143_08775	COG0492	ferredoxin-NADP+ reductase activity
FY143_08780	COG0583	DNA-binding transcription factor activity
FY143_08790	COG1902	pentaerythritol trinitrate reductase activity
FY143_08815	COG0387	Pfam Sodium calcium exchanger
FY143_08820	COG0436	Aminotransferase
FY143_08825	COG2199	diguanylate cyclase activity
FY143_08825	COG2200	EAL domain
FY143_08840	COG1278	Cold shock
FY143_08845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY143_08855	COG1846	Transcriptional regulator
FY143_08860	COG0745	RESPONSE REGULATOR receiver
FY143_08865	COG2205	protein histidine kinase activity
FY143_08870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY143_08890	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY143_08900	COG1496	oxidoreductase activity
FY143_08915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY143_08925	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY143_08940	COG0840	transmembrane signaling receptor activity
FY143_08945	COG1012	belongs to the aldehyde dehydrogenase family
FY143_08955	COG3300	MHYT domain
FY143_08955	COG5001	Diguanylate cyclase
FY143_08960	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY143_08965	COG5001	Diguanylate cyclase
FY143_08975	COG0193	aminoacyl-tRNA hydrolase activity
FY143_08985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY143_09005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY143_09010	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY143_09020	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY143_09020	COG2857	Cytochrome c1
FY143_09040	COG1132	(ABC) transporter
FY143_09045	COG1132	(ABC) transporter
FY143_09050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY143_09065	COG0408	coproporphyrinogen oxidase activity
FY143_09080	COG0617	tRNA 3'-terminal CCA addition
FY143_09095	COG0714	Associated with various cellular activities
FY143_09115	COG0454	-acetyltransferase
FY143_09120	COG0477	Major facilitator Superfamily
FY143_09130	COG0435	Glutathione S-transferase
FY143_09145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY143_09150	COG3135	benzoate transporter
FY143_09155	COG4944	Protein of unknown function (DUF1109)
FY143_09170	COG0740	serine-type endopeptidase activity
FY143_09185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY143_09190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY143_09220	COG4175	Glycine betaine
FY143_09235	COG1435	thymidine kinase activity
FY143_09255	COG2862	Uncharacterized protein family, UPF0114
FY143_09270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY143_09270	COG0512	Glutamine amidotransferase of anthranilate synthase
FY143_09280	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY143_09290	COG0366	Alpha amylase catalytic
FY143_09295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_09310	COG1160	GTP binding
FY143_09330	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY143_09340	COG0024	Methionine aminopeptidase
FY143_09355	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_09365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY143_09375	COG0583	DNA-binding transcription factor activity
FY143_09390	COG0402	S-adenosylhomocysteine deaminase activity
FY143_09415	COG1309	transcriptional regulator
FY143_09420	COG1686	Belongs to the peptidase S11 family
FY143_09430	COG2351	hydroxyisourate hydrolase activity
FY143_09435	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY143_09460	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY143_09470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_09470	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY143_09475	COG0784	Response regulator, receiver
FY143_09475	COG2205	protein histidine kinase activity
FY143_09475	COG5002	protein histidine kinase activity
FY143_09480	COG0513	Belongs to the DEAD box helicase family
FY143_09490	COG2259	Doxx family
FY143_09495	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_09505	COG2308	Evidence 4 Homologs of previously reported genes of
FY143_09515	COG1305	Transglutaminase-like
FY143_09545	COG4214	carbohydrate transport
FY143_09550	COG1129	ABC transporter
FY143_09555	COG4213	ABC transporter substrate-binding protein
FY143_09590	COG0840	transmembrane signaling receptor activity
FY143_09610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_09640	COG1215	transferase activity, transferring glycosyl groups
FY143_09655	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FY143_09670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY143_09675	COG2346	COG2346, Truncated hemoglobins
FY143_09695	COG1309	transcriptional regulator
FY143_09710	COG0494	nUDIX hydrolase
FY143_09720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_09725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_09755	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY143_09760	COG0830	nickel cation binding
FY143_09765	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY143_09780	COG0804	urea catabolic process
FY143_09785	COG1442	glycosyl transferase family 8
FY143_09790	COG3755	Protein conserved in bacteria
FY143_09800	COG0832	Belongs to the urease beta subunit family
FY143_09805	COG3813	Protein conserved in bacteria
FY143_09810	COG0831	urea catabolic process
FY143_09815	COG0829	nickel cation binding
FY143_09830	COG0411	ABC transporter
FY143_09840	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY143_09855	COG0174	glutamine synthetase
FY143_09860	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_09865	COG0784	Response regulator, receiver
FY143_09865	COG2198	Histidine kinase
FY143_09865	COG5002	protein histidine kinase activity
FY143_09910	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY143_09985	COG0564	pseudouridine synthase activity
FY143_10000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY143_10010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY143_10035	COG0346	lactoylglutathione lyase activity
FY143_10045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY143_10055	COG2832	Protein of unknown function (DUF454)
FY143_10060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY143_10065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_10070	COG4558	Periplasmic binding protein
FY143_10080	COG3721	Heme iron utilization protein
FY143_10100	COG2205	protein histidine kinase activity
FY143_10140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_10145	COG4605	iron ion homeostasis
FY143_10150	COG4604	ABC transporter, ATP-binding protein
FY143_10155	COG0783	Belongs to the Dps family
FY143_10170	COG0840	transmembrane signaling receptor activity
FY143_10170	COG2972	Histidine kinase
FY143_10180	COG2814	Major facilitator Superfamily
FY143_10190	COG0583	DNA-binding transcription factor activity
FY143_10195	COG0657	acetylesterase activity
FY143_10200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY143_10220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY143_10225	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY143_10230	COG0288	reversible hydration of carbon dioxide
FY143_10240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY143_10260	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY143_10265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY143_10270	COG0778	Nitroreductase
FY143_10275	COG2267	carboxylic ester hydrolase activity
FY143_10280	COG0251	oxidation-reduction process
FY143_10285	COG1335	isochorismatase
FY143_10290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_10300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_10315	COG1175	transmembrane transport
FY143_10320	COG0395	ABC-type sugar transport system, permease component
FY143_10325	COG3842	ATPase activity
FY143_10330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_10340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY143_10355	COG4608	Belongs to the ABC transporter superfamily
FY143_10360	COG0444	Belongs to the ABC transporter superfamily
FY143_10365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_10370	COG0601	transmembrane transport
FY143_10390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FY143_10390	COG0392	lysyltransferase activity
FY143_10430	COG2159	amidohydrolase
FY143_10435	COG1960	acyl-CoA dehydrogenase activity
FY143_10460	COG0745	RESPONSE REGULATOR receiver
FY143_10470	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY143_10470	COG1902	pentaerythritol trinitrate reductase activity
FY143_10475	COG3842	ATPase activity
FY143_10485	COG1840	ABC-type Fe3 transport system, periplasmic component
FY143_10490	COG1840	ABC-type Fe3 transport system, periplasmic component
FY143_10495	COG0745	RESPONSE REGULATOR receiver
FY143_10510	COG1192	Involved in chromosome partitioning
FY143_10515	COG2201	protein-glutamate methylesterase activity
FY143_10520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY143_10525	COG0835	chemotaxis
FY143_10530	COG0840	transmembrane signaling receptor activity
FY143_10535	COG0835	chemotaxis
FY143_10540	COG0643	Histidine kinase
FY143_10540	COG2198	Histidine kinase
FY143_10605	COG0277	FAD linked oxidase domain protein
FY143_10615	COG1017	nitric oxide dioxygenase activity
FY143_10615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY143_10650	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY143_10660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY143_10665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY143_10675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY143_10700	COG0583	DNA-binding transcription factor activity
FY143_10705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_10710	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY143_10715	COG4149	molybdate abc transporter
FY143_10720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY143_10735	COG2022	thiamine diphosphate biosynthetic process
FY143_10750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY143_10755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY143_10765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY143_10785	COG1132	(ABC) transporter
FY143_10790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY143_10815	COG0438	transferase activity, transferring glycosyl groups
FY143_10835	COG4166	transmembrane transport
FY143_10840	COG0601	transmembrane transport
FY143_10845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_10855	COG0438	transferase activity, transferring glycosyl groups
FY143_10860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY143_10865	COG3142	Participates in the control of copper homeostasis
FY143_10870	COG2814	Major facilitator Superfamily
FY143_10885	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_10890	COG1737	Transcriptional regulator
FY143_10900	COG3842	ATPase activity
FY143_10910	COG0395	ABC-type sugar transport system, permease component
FY143_10925	COG2188	Transcriptional regulator
FY143_10930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY143_10935	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY143_10940	COG1940	carbohydrate kinase activity
FY143_10950	COG0671	phosphoesterase, PA-phosphatase related
FY143_10955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY143_10960	COG0156	8-amino-7-oxononanoate synthase activity
FY143_10970	COG0729	surface antigen
FY143_10980	COG0835	chemotaxis
FY143_10990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY143_10995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY143_11000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY143_11005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY143_11010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY143_11015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY143_11030	COG4974	Belongs to the 'phage' integrase family
FY143_11055	COG1280	lysine exporter protein (LysE YggA)
FY143_11065	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY143_11070	COG0567	Dehydrogenase, E1 component
FY143_11075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY143_11080	COG0045	succinate-CoA ligase (ADP-forming) activity
FY143_11085	COG0039	L-malate dehydrogenase activity
FY143_11090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY143_11125	COG2264	protein methyltransferase activity
FY143_11140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY143_11145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY143_11150	COG0181	hydroxymethylbilane synthase activity
FY143_11190	COG1872	DUF167
FY143_11195	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY143_11205	COG1217	gtp-binding protein TYPA
FY143_11210	COG0339	signal peptide processing
FY143_11220	COG1846	Transcriptional regulator
FY143_11230	COG0137	argininosuccinate synthase activity
FY143_11240	COG1280	lysine exporter protein (LysE YggA)
FY143_11245	COG1122	ATPase activity
FY143_11250	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY143_11260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY143_11275	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY143_11280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY143_11285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY143_11295	COG4181	ATPase activity
FY143_11305	COG0670	Belongs to the BI1 family
FY143_11320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY143_11325	COG4133	protoheme IX ABC transporter activity
FY143_11330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY143_11335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY143_11360	COG2917	probably involved in intracellular septation
FY143_11365	COG0552	protein localization to endoplasmic reticulum
FY143_11370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY143_11375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY143_11385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY143_11390	COG0287	Prephenate dehydrogenase
FY143_11390	COG1605	Chorismate mutase
FY143_11395	COG0228	four-way junction DNA binding
FY143_11400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY143_11405	COG0336	Belongs to the RNA methyltransferase TrmD family
FY143_11415	COG0335	large ribosomal subunit rRNA binding
FY143_11420	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY143_11425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY143_11440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY143_11450	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY143_11470	COG0488	(ABC) transporter
FY143_11480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY143_11490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY143_11495	COG0142	geranyltranstransferase activity
FY143_11500	COG2885	chlorophyll binding
FY143_11505	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY143_11510	COG2223	nitrite transmembrane transporter activity
FY143_11515	COG1349	DNA-binding transcription factor activity
FY143_11520	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY143_11525	COG2197	response regulator
FY143_11530	COG1132	(ABC) transporter
FY143_11535	COG3459	Glycosyltransferase 36 associated
FY143_11540	COG1473	amidohydrolase
FY143_11545	COG0579	oxidoreductase
FY143_11555	COG0129	dihydroxy-acid dehydratase activity
FY143_11560	COG2084	Dehydrogenase
FY143_11565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_11570	COG0277	FAD linked oxidase domain protein
FY143_11575	COG2186	Transcriptional regulator
FY143_11585	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY143_11590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY143_11595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY143_11600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY143_11615	COG0495	leucyl-tRNA aminoacylation
FY143_11630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY143_11635	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY143_11645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY143_11650	COG1946	Acyl-CoA thioesterase
FY143_11655	COG0347	Belongs to the P(II) protein family
FY143_11660	COG0004	ammonium transporteR
FY143_11665	COG1674	ftsk spoiiie
FY143_11670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY143_11685	COG0745	RESPONSE REGULATOR receiver
FY143_11695	COG1329	Transcriptional regulator
FY143_11700	COG2902	Dehydrogenase
FY143_11705	COG2270	Major facilitator Superfamily
FY143_11720	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_11735	COG0494	nUDIX hydrolase
FY143_11745	COG0793	Belongs to the peptidase S41A family
FY143_11755	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY143_11760	COG0799	negative regulation of ribosome biogenesis
FY143_11765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY143_11770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY143_11775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY143_11780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY143_11795	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY143_11800	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY143_11825	COG0066	3-isopropylmalate dehydratase activity
FY143_11830	COG0473	3-isopropylmalate dehydrogenase activity
FY143_11835	COG1858	cytochrome C peroxidase
FY143_11840	COG1797	cobyrinic acid a,c-diamide synthase activity
FY143_11845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY143_11845	COG1648	precorrin-2 dehydrogenase activity
FY143_11850	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY143_11915	COG1492	cobalamin metabolic process
FY143_11930	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_11935	COG3254	rhamnose metabolic process
FY143_11940	COG0246	Mannitol dehydrogenase
FY143_11945	COG1063	alcohol dehydrogenase
FY143_11965	COG4214	carbohydrate transport
FY143_11970	COG1129	ABC transporter
FY143_11975	COG2186	Transcriptional regulator
FY143_11980	COG2721	sulfolactate sulfo-lyase activity
FY143_11985	COG0138	bifunctional purine biosynthesis protein purh
FY143_11995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY143_11995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY143_12000	COG0501	Belongs to the peptidase M48B family
FY143_12020	COG0357	Ribosomal RNA small subunit methyltransferase G
FY143_12025	COG0445	tRNA wobble uridine modification
FY143_12030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY143_12035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY143_12040	COG1981	membrane
FY143_12045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY143_12050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY143_12055	COG0424	maF-like protein
FY143_12060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY143_12065	COG0237	dephospho-CoA kinase activity
FY143_12075	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY143_12090	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY143_12115	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY143_12130	COG0135	phosphoribosylanthranilate isomerase activity
FY143_12135	COG0133	tryptophan synthase activity
FY143_12140	COG0159	tryptophan synthase activity
FY143_12145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY143_12160	COG1074	ATP-dependent DNA helicase activity
FY143_12170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY143_12175	COG0802	atpase or kinase
FY143_12180	COG2205	protein histidine kinase activity
FY143_12185	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY143_12190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY143_12195	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY143_12195	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY143_12200	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY143_12205	COG0642	Histidine kinase
FY143_12210	COG0745	RESPONSE REGULATOR receiver
FY143_12215	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY143_12225	COG1652	LysM domain
FY143_12230	COG1072	(Pantothenic acid kinase))
FY143_12235	COG0140	phosphoribosyl-ATP diphosphatase activity
FY143_12240	COG0107	imidazoleglycerol-phosphate synthase activity
FY143_12245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY143_12250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY143_12260	COG0131	Imidazoleglycerol-phosphate dehydratase
FY143_12265	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY143_12270	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY143_12280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY143_12295	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY143_12305	COG1643	Atp-dependent helicase
FY143_12365	COG1072	(Pantothenic acid kinase))
FY143_12375	COG1780	Probably involved in ribonucleotide reductase function
FY143_12395	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY143_12420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_12435	COG1185	polyribonucleotide nucleotidyltransferase activity
FY143_12440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY143_12445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY143_12450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY143_12455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY143_12455	COG3064	Membrane
FY143_12470	COG0779	Required for maturation of 30S ribosomal subunits
FY143_12475	COG2814	Major facilitator Superfamily
FY143_12480	COG2951	lytic endotransglycosylase activity
FY143_12485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY143_12495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY143_12500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY143_12515	COG2816	NAD+ diphosphatase activity
FY143_12520	COG0077	Prephenate dehydratase
FY143_12520	COG1605	Chorismate mutase
FY143_12525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY143_12530	COG3474	cytochrome
FY143_12540	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY143_12545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY143_12550	COG1278	Cold shock
FY143_12555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY143_12565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY143_12565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY143_12575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY143_12605	COG2900	Belongs to the SlyX family
FY143_12615	COG0484	heat shock protein binding
FY143_12620	COG0443	Heat shock 70 kDa protein
FY143_12635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY143_12640	COG1744	ABC transporter substrate-binding protein PnrA-like
FY143_12645	COG3845	ABC transporter
FY143_12650	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY143_12655	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY143_12660	COG0295	cytidine deaminase activity
FY143_12670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY143_12675	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY143_12685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY143_12690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY143_12695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY143_12710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY143_12715	COG1845	cytochrome c oxidase, subunit III
FY143_12720	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY143_12725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY143_12730	COG0477	Major facilitator Superfamily
FY143_12735	COG0070	glutamate synthase
FY143_12735	COG0067	glutamate synthase
FY143_12735	COG0069	glutamate synthase activity
FY143_12740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY143_12755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY143_12765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY143_12805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_12825	COG0848	biopolymer transport protein
FY143_12835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY143_12850	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY143_12855	COG3454	Phosphonate metabolism
FY143_12860	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY143_12865	COG3639	organic phosphonate transmembrane transporter activity
FY143_12870	COG3639	organic phosphonate transmembrane transporter activity
FY143_12880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY143_12890	COG4778	phosphonate C-P lyase system protein PhnL
FY143_12895	COG4107	phosphonate C-P lyase system protein PhnK
FY143_12900	COG3627	carbon phosphorus lyase activity
FY143_12905	COG3626	phosphonate metabolism
FY143_12910	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY143_12915	COG3624	Phosphonate C-P lyase system protein PhnG
FY143_12920	COG2188	Transcriptional regulator
FY143_12925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY143_12930	COG0837	glucose binding
FY143_12935	COG1803	Methylglyoxal synthase
FY143_12940	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY143_12945	COG4166	transmembrane transport
FY143_12950	COG4174	ABC transporter (Permease)
FY143_12955	COG4239	(ABC) transporter, permease
FY143_12960	COG4172	Belongs to the ABC transporter superfamily
FY143_12965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_12970	COG0174	glutamine synthetase
FY143_12975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_12980	COG3265	gluconokinase activity
FY143_12985	COG1174	glycine betaine transport
FY143_12990	COG1125	glycine betaine transport
FY143_12995	COG1174	glycine betaine transport
FY143_13000	COG1732	Glycine betaine
FY143_13010	COG1959	2 iron, 2 sulfur cluster binding
FY143_13015	COG1840	ABC-type Fe3 transport system, periplasmic component
FY143_13035	COG0697	spore germination
FY143_13050	COG0791	NLP P60 protein
FY143_13060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY143_13065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY143_13100	COG4964	Belongs to the GSP D family
FY143_13140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY143_13145	COG3422	double-strand break repair
FY143_13150	COG3757	hydrolase, family 25
FY143_13155	COG0697	spore germination
FY143_13160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY143_13190	COG0481	GTPase activity
FY143_13195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY143_13225	COG1917	Cupin 2, conserved barrel domain protein
FY143_13225	COG2169	Transcriptional regulator
FY143_13230	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY143_13255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY143_13260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY143_13265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY143_13275	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY143_13280	COG0072	phenylalanine-tRNA ligase activity
FY143_13280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY143_13285	COG0667	Aldo Keto reductase
FY143_13305	COG4977	sequence-specific DNA binding
FY143_13330	COG1570	exodeoxyribonuclease VII activity
FY143_13335	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_13345	COG1846	Transcriptional regulator
FY143_13350	COG0697	spore germination
FY143_13355	COG2309	aminopeptidase activity
FY143_13365	COG1393	Belongs to the ArsC family
FY143_13375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY143_13375	COG0519	Catalyzes the synthesis of GMP from XMP
FY143_13390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY143_13420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY143_13430	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY143_13440	COG1968	undecaprenyl-diphosphatase activity
FY143_13455	COG0284	orotidine-5'-phosphate decarboxylase activity
FY143_13465	COG3963	phosphatidate phosphatase activity
FY143_13475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY143_13480	COG0792	nuclease activity
FY143_13495	COG1175	transmembrane transport
FY143_13500	COG0395	ABC-type sugar transport system, permease component
FY143_13505	COG3842	ATPase activity
FY143_13515	COG0189	ligase activity
FY143_13525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY143_13530	COG1280	lysine exporter protein (LysE YggA)
FY143_13535	COG0756	dUTP diphosphatase activity
FY143_13540	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY143_13545	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY143_13560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY143_13565	COG2226	methyltransferase
FY143_13570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY143_13575	COG1024	Enoyl-CoA hydratase
FY143_13580	COG0268	Binds directly to 16S ribosomal RNA
FY143_13590	COG2161	toxin-antitoxin pair type II binding
FY143_13675	COG4529	Protein conserved in bacteria
FY143_13710	COG0406	alpha-ribazole phosphatase activity
FY143_13750	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY143_13765	COG4172	Belongs to the ABC transporter superfamily
FY143_13770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_13775	COG0601	transmembrane transport
FY143_13780	COG0747	negative chemotaxis
FY143_13800	COG0583	DNA-binding transcription factor activity
FY143_13805	COG2814	Major facilitator Superfamily
FY143_13825	COG4106	trans-aconitate 2-methyltransferase activity
FY143_13875	COG0297	glycogen (starch) synthase activity
FY143_13880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY143_13915	COG3685	Protein conserved in bacteria
FY143_13920	COG0753	catalase activity
FY143_14160	COG1522	sequence-specific DNA binding
FY143_14170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY143_14175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY143_14180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY143_14185	COG2423	ornithine cyclodeaminase activity
FY143_14190	COG0006	proline dipeptidase activity
FY143_14195	COG3608	succinylglutamate desuccinylase aspartoacylase
FY143_14200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_14205	COG0765	amino acid transport
FY143_14210	COG0765	amino acid transport
FY143_14215	COG1126	abc transporter atp-binding protein
FY143_14230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY143_14245	COG1309	transcriptional regulator
FY143_14250	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_14260	COG1595	DNA-templated transcription, initiation
FY143_14270	COG0438	transferase activity, transferring glycosyl groups
FY143_14270	COG1216	Glycosyl transferase, family 2
FY143_14290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY143_14330	COG0438	transferase activity, transferring glycosyl groups
FY143_14330	COG1216	Glycosyl transferase, family 2
FY143_14340	COG1368	sulfuric ester hydrolase activity
FY143_14345	COG0300	oxidoreductase activity
FY143_14350	COG0156	8-amino-7-oxononanoate synthase activity
FY143_14355	COG0604	alcohol dehydrogenase
FY143_14355	COG3321	synthase
FY143_14355	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_14370	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY143_14375	COG1088	dTDP-glucose 4,6-dehydratase activity
FY143_14380	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY143_14385	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY143_14395	COG0372	Belongs to the citrate synthase family
FY143_14400	COG0372	Belongs to the citrate synthase family
FY143_14435	COG3046	protein related to deoxyribodipyrimidine photolyase
FY143_14440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY143_14450	COG5001	Diguanylate cyclase
FY143_14450	COG2203	Gaf domain
FY143_14450	COG3706	GGDEF domain
FY143_14450	COG4251	negative regulation of phosphorylation
FY143_14455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY143_14475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY143_14520	COG0753	catalase activity
FY143_14530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FY143_14540	COG0640	Transcriptional regulator
FY143_14545	COG5265	(ABC) transporter
FY143_14555	COG3181	Tripartite tricarboxylate transporter family receptor
FY143_14560	COG2197	response regulator
FY143_14565	COG3237	CsbD-like
FY143_14595	COG0456	acetyltransferase
FY143_14600	COG2223	nitrite transmembrane transporter activity
FY143_14610	COG3383	formate dehydrogenase (NAD+) activity
FY143_14635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY143_14640	COG1802	Transcriptional regulator
FY143_14645	COG4608	Belongs to the ABC transporter superfamily
FY143_14650	COG0444	Belongs to the ABC transporter superfamily
FY143_14655	COG0402	S-adenosylhomocysteine deaminase activity
FY143_14665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_14670	COG0601	transmembrane transport
FY143_14680	COG0402	S-adenosylhomocysteine deaminase activity
FY143_14695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY143_14705	COG0765	amino acid transport
FY143_14710	COG0765	amino acid transport
FY143_14715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_14730	COG3938	Belongs to the proline racemase family
FY143_14740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_14750	COG0765	amino acid transport
FY143_14765	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY143_14770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_14780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY143_14785	COG0784	Response regulator, receiver
FY143_14800	COG1486	melibiose metabolic process
FY143_14805	COG4172	Belongs to the ABC transporter superfamily
FY143_14810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_14815	COG0601	transmembrane transport
FY143_14820	COG0747	negative chemotaxis
FY143_14825	COG1486	melibiose metabolic process
FY143_14850	COG1940	carbohydrate kinase activity
FY143_14855	COG2182	Extracellular solute-binding protein
FY143_14860	COG1175	transmembrane transport
FY143_14865	COG0395	ABC-type sugar transport system, permease component
FY143_14870	COG0165	Argininosuccinate lyase
FY143_14875	COG3842	ATPase activity
FY143_14880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_14885	COG3119	arylsulfatase activity
FY143_14895	COG0583	DNA-binding transcription factor activity
FY143_14900	COG1012	belongs to the aldehyde dehydrogenase family
FY143_14925	COG1733	regulation of RNA biosynthetic process
FY143_14930	COG1120	ATPase activity
FY143_14935	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_14950	COG4774	siderophore transport
FY143_14960	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY143_14975	COG5002	protein histidine kinase activity
FY143_14980	COG0745	RESPONSE REGULATOR receiver
FY143_15000	COG1392	Phosphate transport regulator
FY143_15005	COG0306	phosphate transporter
FY143_15010	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY143_15020	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY143_15030	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_15035	COG3300	MHYT domain
FY143_15035	COG5001	Diguanylate cyclase
FY143_15045	COG0747	negative chemotaxis
FY143_15055	COG2186	Transcriptional regulator
FY143_15060	COG0601	transmembrane transport
FY143_15065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_15070	COG0444	Belongs to the ABC transporter superfamily
FY143_15075	COG4608	Belongs to the ABC transporter superfamily
FY143_15080	COG3842	ATPase activity
FY143_15085	COG0395	ABC-type sugar transport system, permease component
FY143_15100	COG1233	COG1233 Phytoene dehydrogenase and related
FY143_15105	COG1609	Transcriptional regulator
FY143_15120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY143_15140	COG2226	methyltransferase
FY143_15150	COG2942	2-epimerase
FY143_15155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_15160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FY143_15160	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FY143_15165	COG0438	transferase activity, transferring glycosyl groups
FY143_15170	COG1132	(ABC) transporter
FY143_15180	COG0385	Bile acid
FY143_15200	COG1177	transmembrane transport
FY143_15205	COG3842	ATPase activity
FY143_15220	COG0483	inositol monophosphate 1-phosphatase activity
FY143_15225	COG0584	glycerophosphoryl diester phosphodiesterase
FY143_15235	COG4149	molybdate abc transporter
FY143_15240	COG3842	ATPase activity
FY143_15270	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY143_15285	COG1175	transmembrane transport
FY143_15290	COG0395	ABC-type sugar transport system, permease component
FY143_15295	COG1609	Transcriptional regulator
FY143_15305	COG0673	inositol 2-dehydrogenase activity
FY143_15310	COG1082	Xylose isomerase domain protein TIM barrel
FY143_15320	COG1609	Transcriptional regulator
FY143_15325	COG0183	Belongs to the thiolase family
FY143_15330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY143_15340	COG1414	Transcriptional regulator
FY143_15355	COG0583	DNA-binding transcription factor activity
FY143_15365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY143_15370	COG3485	protocatechuate 3,4-dioxygenase
FY143_15375	COG3485	protocatechuate 3,4-dioxygenase
FY143_15385	COG0765	amino acid transport
FY143_15390	COG0765	amino acid transport
FY143_15395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_15400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_15405	COG1126	abc transporter atp-binding protein
FY143_15410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY143_15415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY143_15425	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FY143_15425	COG1082	Xylose isomerase domain protein TIM barrel
FY143_15440	COG0747	negative chemotaxis
FY143_15450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_15465	COG0683	leucine binding
FY143_15480	COG0411	ABC transporter
FY143_15485	COG3842	ATPase activity
FY143_15495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_15500	COG3962	Belongs to the TPP enzyme family
FY143_15510	COG3718	enzyme involved in inositol metabolism
FY143_15515	COG0673	inositol 2-dehydrogenase activity
FY143_15520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY143_15525	COG1609	Transcriptional regulator
FY143_15530	COG1846	Transcriptional regulator
FY143_15540	COG0523	cobalamin synthesis protein
FY143_15575	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY143_15595	COG0800	Aldolase
FY143_15600	COG2954	triphosphatase activity
FY143_15610	COG1054	Belongs to the UPF0176 family
FY143_15615	COG3300	MHYT domain
FY143_15615	COG5001	Diguanylate cyclase
FY143_15625	COG2011	ABC-type metal ion transport system permease component
FY143_15630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY143_15635	COG0778	Nitroreductase
FY143_15645	COG2115	Belongs to the xylose isomerase family
FY143_15650	COG1070	Carbohydrate kinase
FY143_15655	COG1609	Transcriptional regulator
FY143_15670	COG1309	transcriptional regulator
FY143_15675	COG1253	flavin adenine dinucleotide binding
FY143_15680	COG0471	metal ion transport
FY143_15680	COG3273	potassium ion transport
FY143_15685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY143_15690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY143_15700	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY143_15705	COG1121	(ABC) transporter
FY143_15710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY143_15715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY143_15720	COG5487	UPF0391 membrane protein
FY143_15725	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_15730	COG1414	Transcriptional regulator
FY143_15735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY143_15745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY143_15790	COG0395	ABC-type sugar transport system, permease component
FY143_15795	COG1175	transmembrane transport
FY143_15805	COG2390	Transcriptional regulator
FY143_15810	COG4172	Belongs to the ABC transporter superfamily
FY143_15815	COG1473	amidohydrolase
FY143_15825	COG0601	transmembrane transport
FY143_15830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_15840	COG0693	protein deglycase activity
FY143_15850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_15860	COG0747	negative chemotaxis
FY143_15865	COG0583	DNA-binding transcription factor activity
FY143_15870	COG4608	Belongs to the ABC transporter superfamily
FY143_15875	COG0444	Belongs to the ABC transporter superfamily
FY143_15880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_15885	COG0601	transmembrane transport
FY143_15890	COG0747	negative chemotaxis
FY143_15900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY143_15905	COG1473	amidohydrolase
FY143_15910	COG2814	Major facilitator Superfamily
FY143_15915	COG0583	DNA-binding transcription factor activity
FY143_15920	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY143_15940	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_15950	COG1609	Transcriptional regulator
FY143_15955	COG0583	DNA-binding transcription factor activity
FY143_15960	COG1960	acyl-CoA dehydrogenase activity
FY143_15965	COG4774	siderophore transport
FY143_15965	COG1629	transport
FY143_15980	COG1120	ATPase activity
FY143_15985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_15990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_16000	COG2375	cellular response to nickel ion
FY143_16010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY143_16015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY143_16015	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY143_16025	COG1169	isochorismate synthase
FY143_16030	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY143_16035	COG1535	isochorismatase
FY143_16035	COG3433	isochorismatase activity
FY143_16040	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_16070	COG0668	transmembrane transport
FY143_16080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY143_16090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY143_16090	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY143_16100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_16115	COG1609	Transcriptional regulator
FY143_16120	COG0673	inositol 2-dehydrogenase activity
FY143_16130	COG1653	transport
FY143_16135	COG1175	transmembrane transport
FY143_16140	COG0395	ABC-type sugar transport system, permease component
FY143_16145	COG3842	ATPase activity
FY143_16160	COG1253	flavin adenine dinucleotide binding
FY143_16190	COG3842	ATPase activity
FY143_16195	COG1178	ABC-type Fe3 transport system permease component
FY143_16220	COG0483	inositol monophosphate 1-phosphatase activity
FY143_16230	COG0477	Major facilitator Superfamily
FY143_16250	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_16260	COG1879	ABC-type sugar transport system periplasmic component
FY143_16270	COG1063	alcohol dehydrogenase
FY143_16275	COG1309	transcriptional regulator
FY143_16295	COG1312	Catalyzes the dehydration of D-mannonate
FY143_16300	COG0246	Mannitol dehydrogenase
FY143_16305	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_16320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_16330	COG1129	ABC transporter
FY143_16335	COG4977	sequence-specific DNA binding
FY143_16340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_16345	COG4311	Sarcosine oxidase, delta subunit
FY143_16350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY143_16350	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY143_16370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY143_16375	COG0318	PFAM AMP-dependent synthetase and ligase
FY143_16385	COG0367	asparagine synthase
FY143_16395	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY143_16400	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FY143_16425	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FY143_16430	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_16445	COG1609	Transcriptional regulator
FY143_16460	COG3300	MHYT domain
FY143_16460	COG5001	Diguanylate cyclase
FY143_16470	COG0840	transmembrane signaling receptor activity
FY143_16475	COG4166	transmembrane transport
FY143_16480	COG0601	transmembrane transport
FY143_16485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_16490	COG4172	Belongs to the ABC transporter superfamily
FY143_16510	COG2986	histidine ammonia-lyase
FY143_16540	COG1278	Cold shock
FY143_16560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY143_16565	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY143_16570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY143_16575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY143_16580	COG2080	2 iron, 2 sulfur cluster binding
FY143_16600	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY143_16620	COG0346	lactoylglutathione lyase activity
FY143_16625	COG0583	DNA-binding transcription factor activity
FY143_16630	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY143_16645	COG1846	Transcriptional regulator
FY143_16650	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_16660	COG0583	DNA-binding transcription factor activity
FY143_16670	COG0783	Belongs to the Dps family
FY143_16675	COG2140	Oxalate decarboxylase
FY143_16685	COG4566	intracellular signal transduction
FY143_16700	COG0492	ferredoxin-NADP+ reductase activity
FY143_16710	COG2814	Major facilitator Superfamily
FY143_16715	COG0243	molybdopterin cofactor binding
FY143_16725	COG0604	alcohol dehydrogenase
FY143_16730	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_16735	COG1902	pentaerythritol trinitrate reductase activity
FY143_16740	COG4221	oxidoreductase activity
FY143_16745	COG1309	transcriptional regulator
FY143_16755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY143_16770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY143_16775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY143_16815	COG1196	nuclear chromosome segregation
FY143_16815	COG0741	lytic transglycosylase activity
FY143_16815	COG0739	heme binding
FY143_16820	COG0542	response to heat
FY143_16830	COG2890	protein-(glutamine-N5) methyltransferase activity
FY143_16835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY143_16845	COG0527	aspartate kinase activity
FY143_16860	COG0019	diaminopimelate decarboxylase activity
FY143_16875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY143_16895	COG0784	Response regulator, receiver
FY143_16910	COG1522	sequence-specific DNA binding
FY143_16920	COG1116	anion transmembrane transporter activity
FY143_16925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_16930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY143_16935	COG1012	belongs to the aldehyde dehydrogenase family
FY143_16940	COG0583	DNA-binding transcription factor activity
FY143_16945	COG0435	Glutathione S-transferase
FY143_16955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY143_16960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_16965	COG0189	ligase activity
FY143_16990	COG0693	protein deglycase activity
FY143_17000	COG3685	Protein conserved in bacteria
FY143_17005	COG4993	Dehydrogenase
FY143_17025	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_17030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY143_17050	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY143_17060	COG0411	ABC transporter
FY143_17075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_17090	COG4608	Belongs to the ABC transporter superfamily
FY143_17095	COG0444	Belongs to the ABC transporter superfamily
FY143_17100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_17105	COG0601	transmembrane transport
FY143_17110	COG0747	negative chemotaxis
FY143_17115	COG0006	proline dipeptidase activity
FY143_17120	COG4221	oxidoreductase activity
FY143_17150	COG0539	negative regulation of cytoplasmic translation
FY143_17155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY143_17185	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY143_17190	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY143_17220	COG1294	oxidase, subunit
FY143_17230	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY143_17235	COG4988	ABC transporter
FY143_17245	COG1063	alcohol dehydrogenase
FY143_17250	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_17255	COG2084	Dehydrogenase
FY143_17265	COG1522	sequence-specific DNA binding
FY143_17270	COG1794	racemase activity, acting on amino acids and derivatives
FY143_17285	COG0058	SHG alpha-glucan phosphorylase activity
FY143_17290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY143_17295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY143_17300	COG0297	glycogen (starch) synthase activity
FY143_17305	COG0033	Phosphoglucomutase
FY143_17310	COG1523	belongs to the glycosyl hydrolase 13 family
FY143_17335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY143_17335	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY143_17350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_17355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY143_17375	COG1215	transferase activity, transferring glycosyl groups
FY143_17380	COG2327	Polysaccharide pyruvyl transferase
FY143_17385	COG0463	Glycosyl transferase, family 2
FY143_17390	COG2244	polysaccharide biosynthetic process
FY143_17395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY143_17400	COG2273	Hydrolase Family 16
FY143_17405	COG0438	transferase activity, transferring glycosyl groups
FY143_17410	COG1215	transferase activity, transferring glycosyl groups
FY143_17415	COG1215	transferase activity, transferring glycosyl groups
FY143_17420	COG1215	transferase activity, transferring glycosyl groups
FY143_17425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY143_17430	COG0489	protein tyrosine kinase activity
FY143_17430	COG3206	protein involved in exopolysaccharide biosynthesis
FY143_17440	COG4191	Histidine kinase
FY143_17440	COG0784	Response regulator, receiver
FY143_17450	COG4176	ABC-type proline glycine betaine transport system permease component
FY143_17455	COG4175	Glycine betaine
FY143_17455	COG0517	IMP dehydrogenase activity
FY143_17470	COG0564	pseudouridine synthase activity
FY143_17475	COG0500	methyltransferase
FY143_17485	COG2133	pyrroloquinoline quinone binding
FY143_17495	COG2197	response regulator
FY143_17500	COG4585	Histidine kinase
FY143_17505	COG1879	ABC-type sugar transport system periplasmic component
FY143_17510	COG1129	ABC transporter
FY143_17515	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_17525	COG3386	PFAM SMP-30 Gluconolaconase
FY143_17530	COG2137	regulation of response to DNA damage stimulus
FY143_17545	COG1120	ATPase activity
FY143_17560	COG4774	siderophore transport
FY143_17565	COG0583	DNA-binding transcription factor activity
FY143_17575	COG2194	sulfuric ester hydrolase activity
FY143_17585	COG0642	Histidine kinase
FY143_17590	COG0477	Major facilitator Superfamily
FY143_17615	COG0673	inositol 2-dehydrogenase activity
FY143_17620	COG0697	spore germination
FY143_17630	COG0010	Belongs to the arginase family
FY143_17645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY143_17650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY143_17655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY143_17665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY143_17715	COG0671	phosphoesterase, PA-phosphatase related
FY143_17720	COG0745	RESPONSE REGULATOR receiver
FY143_17725	COG2205	protein histidine kinase activity
FY143_17745	COG0277	FAD linked oxidase domain protein
FY143_17760	COG0601	transmembrane transport
FY143_17765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_17770	COG4172	Belongs to the ABC transporter superfamily
FY143_17780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_17790	COG0477	Major facilitator Superfamily
FY143_17795	COG0583	DNA-binding transcription factor activity
FY143_17800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY143_17835	COG0673	inositol 2-dehydrogenase activity
FY143_17840	COG0673	inositol 2-dehydrogenase activity
FY143_17850	COG1175	transmembrane transport
FY143_17855	COG0395	ABC-type sugar transport system, permease component
FY143_17860	COG3842	ATPase activity
FY143_17870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_17875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY143_17885	COG0798	PFAM Bile acid sodium symporter
FY143_17895	COG0431	NADPH-dependent FMN reductase
FY143_17905	COG0640	Transcriptional regulator
FY143_17920	COG0765	amino acid transport
FY143_17930	COG1126	abc transporter atp-binding protein
FY143_17935	COG0010	Belongs to the arginase family
FY143_17940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY143_17945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_17950	COG1126	abc transporter atp-binding protein
FY143_17955	COG0765	amino acid transport
FY143_17960	COG0765	amino acid transport
FY143_17965	COG4221	oxidoreductase activity
FY143_17975	COG0436	Aminotransferase
FY143_17980	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY143_17985	COG1984	allophanate hydrolase subunit 2
FY143_18000	COG0439	Biotin carboxylase
FY143_18005	COG0511	ligase activity, forming carbon-carbon bonds
FY143_18045	COG0402	S-adenosylhomocysteine deaminase activity
FY143_18050	COG1228	amidohydrolase
FY143_18055	COG2986	histidine ammonia-lyase
FY143_18065	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY143_18070	COG0596	Alpha beta hydrolase
FY143_18100	COG1192	Involved in chromosome partitioning
FY143_18105	COG1475	DNA binding
FY143_18110	COG1414	Transcriptional regulator
FY143_18130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY143_18135	COG4771	TonB-dependent receptor
FY143_18145	COG0366	Alpha amylase catalytic
FY143_18150	COG4770	biotin carboxylase activity
FY143_18155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY143_18160	COG4336	lyase activity
FY143_18165	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY143_18170	COG1914	H( )-stimulated, divalent metal cation uptake system
FY143_18175	COG1802	Transcriptional regulator
FY143_18180	COG3707	response regulator
FY143_18190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY143_18195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_18200	COG1116	anion transmembrane transporter activity
FY143_18205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY143_18215	COG0243	molybdopterin cofactor binding
FY143_18220	COG1648	precorrin-2 dehydrogenase activity
FY143_18220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY143_18235	COG3842	ATPase activity
FY143_18240	COG3842	ATPase activity
FY143_18250	COG0395	ABC-type sugar transport system, permease component
FY143_18265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY143_18280	COG0071	Belongs to the small heat shock protein (HSP20) family
FY143_18310	COG1879	ABC-type sugar transport system periplasmic component
FY143_18315	COG1129	ABC transporter
FY143_18320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_18330	COG0667	Aldo Keto reductase
FY143_18335	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY143_18340	COG1830	Aldolase
FY143_18345	COG1070	Carbohydrate kinase
FY143_18350	COG0840	transmembrane signaling receptor activity
FY143_18355	COG1846	Transcriptional regulator
FY143_18360	COG1304	FMN binding
FY143_18365	COG0488	(ABC) transporter
FY143_18380	COG2307	Protein conserved in bacteria
FY143_18380	COG2308	Evidence 4 Homologs of previously reported genes of
FY143_18430	COG1454	alcohol dehydrogenase
FY143_18435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY143_18445	COG0747	negative chemotaxis
FY143_18450	COG0601	transmembrane transport
FY143_18455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_18465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_18485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY143_18490	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY143_18495	COG0069	glutamate synthase activity
FY143_18500	COG0174	glutamine synthetase
FY143_18520	COG0765	amino acid transport
FY143_18525	COG1126	abc transporter atp-binding protein
FY143_18540	COG2267	carboxylic ester hydrolase activity
FY143_18550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_18555	COG1012	belongs to the aldehyde dehydrogenase family
FY143_18575	COG1177	transmembrane transport
FY143_18580	COG3842	ATPase activity
FY143_18600	COG0583	DNA-binding transcription factor activity
FY143_18620	COG3239	Fatty acid desaturase
FY143_18645	COG2186	Transcriptional regulator
FY143_18650	COG1027	Aspartate ammonia-lyase
FY143_18660	COG0252	asparaginase activity
FY143_18670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY143_18675	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY143_18680	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY143_18685	COG2205	protein histidine kinase activity
FY143_18700	COG0069	glutamate synthase activity
FY143_18700	COG0070	glutamate synthase
FY143_18700	COG0067	glutamate synthase
FY143_18715	COG2205	protein histidine kinase activity
FY143_18730	COG2951	lytic endotransglycosylase activity
FY143_18735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY143_18760	COG0330	HflC and HflK could
FY143_18765	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY143_18770	COG0737	Belongs to the 5'-nucleotidase family
FY143_18780	COG5310	Homospermidine synthase
FY143_18790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY143_18795	COG1164	Oligoendopeptidase f
FY143_18800	COG2204	response regulator
FY143_18805	COG3108	Peptidase M15
FY143_18810	COG0469	pyruvate kinase activity
FY143_18830	COG3750	Belongs to the UPF0335 family
FY143_18835	COG0457	Tetratricopeptide repeat
FY143_18840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY143_18845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY143_18850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY143_18880	COG0483	inositol monophosphate 1-phosphatase activity
FY143_18900	COG1132	(ABC) transporter
FY143_18905	COG0254	rRNA binding
FY143_18925	COG3588	fructose-bisphosphate aldolase
FY143_18930	COG0126	phosphoglycerate kinase activity
FY143_18970	COG1253	flavin adenine dinucleotide binding
FY143_18980	COG1692	metallophosphoesterase
FY143_18995	COG0217	transcriptional regulatory protein
FY143_19000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_19005	COG2972	Histidine kinase
FY143_19005	COG0840	transmembrane signaling receptor activity
FY143_19010	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY143_19015	COG0632	four-way junction helicase activity
FY143_19020	COG2255	four-way junction helicase activity
FY143_19035	COG0494	nUDIX hydrolase
FY143_19045	COG0824	Thioesterase
FY143_19065	COG0823	Involved in the tonB-independent uptake of proteins
FY143_19070	COG2885	chlorophyll binding
FY143_19080	COG0037	tRNA processing
FY143_19085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY143_19090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY143_19105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY143_19120	COG0482	sulfurtransferase activity
FY143_19140	COG3118	belongs to the thioredoxin family
FY143_19150	COG2835	tetraacyldisaccharide 4'-kinase activity
FY143_19155	COG2373	Large extracellular alpha-helical protein
FY143_19160	COG4953	penicillin-binding protein 1C
FY143_19170	COG1473	amidohydrolase
FY143_19270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY143_19305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY143_19310	COG1686	Belongs to the peptidase S11 family
FY143_19315	COG0523	cobalamin synthesis protein
FY143_19320	COG0425	Belongs to the sulfur carrier protein TusA family
FY143_19325	COG3034	peptidoglycan biosynthetic process
FY143_19330	COG0825	malonyl-CoA metabolic process
FY143_19335	COG4974	Belongs to the 'phage' integrase family
FY143_19345	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY143_19350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY143_19385	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY143_19390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY143_19405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY143_19410	COG2226	methyltransferase
FY143_19415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY143_19420	COG0287	Prephenate dehydrogenase
FY143_19435	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY143_19455	COG2884	Cell division ATP-binding protein ftsE
FY143_19490	COG0165	Argininosuccinate lyase
FY143_19495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY143_19500	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY143_19510	COG2086	electron transfer activity
FY143_19520	COG2096	Adenosyltransferase
FY143_19530	COG0300	oxidoreductase activity
FY143_19540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY143_19550	COG1396	sequence-specific DNA binding
FY143_19550	COG3800	Transcriptional regulator
FY143_19555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY143_19560	COG0625	glutathione transferase activity
FY143_19570	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY143_19575	COG4770	biotin carboxylase activity
FY143_19580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY143_19580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY143_19585	COG0346	lactoylglutathione lyase activity
FY143_19595	COG0640	Transcriptional regulator
FY143_19610	COG4213	ABC transporter substrate-binding protein
FY143_19615	COG4214	carbohydrate transport
FY143_19620	COG1129	ABC transporter
FY143_19630	COG1396	sequence-specific DNA binding
FY143_19685	COG3833	ABC-type maltose transport systems, permease component
FY143_19690	COG3842	ATPase activity
FY143_19705	COG2273	Hydrolase Family 16
FY143_19705	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY143_19710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY143_19725	COG0438	transferase activity, transferring glycosyl groups
FY143_19730	COG0438	transferase activity, transferring glycosyl groups
FY143_19770	COG2244	polysaccharide biosynthetic process
FY143_19835	COG0653	protein targeting
FY143_19840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY143_19845	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY143_19855	COG0494	nUDIX hydrolase
FY143_19870	COG2226	methyltransferase
FY143_19875	COG1040	competence protein
FY143_19885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY143_19895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY143_19915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY143_19920	COG4150	thiosulfate binding
FY143_19930	COG4208	sulfate ABC transporter
FY143_19935	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY143_19940	COG4335	DNA alkylation repair
FY143_19955	COG5001	Diguanylate cyclase
FY143_19960	COG2264	protein methyltransferase activity
FY143_19975	COG3254	rhamnose metabolic process
FY143_19980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_19985	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_19990	COG1129	ABC transporter
FY143_20000	COG1349	DNA-binding transcription factor activity
FY143_20005	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_20005	COG3347	Dehydrogenase
FY143_20010	COG4952	isomerase
FY143_20015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY143_20020	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY143_20025	COG1024	Enoyl-CoA hydratase
FY143_20040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY143_20045	COG1960	acyl-CoA dehydrogenase activity
FY143_20055	COG0183	Belongs to the thiolase family
FY143_20060	COG1960	acyl-CoA dehydrogenase activity
FY143_20070	COG0022	dehydrogenase e1 component
FY143_20080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY143_20085	COG2391	methyltransferase activity
FY143_20095	COG0640	Transcriptional regulator
FY143_20100	COG3453	Protein conserved in bacteria
FY143_20100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY143_20110	COG0300	oxidoreductase activity
FY143_20125	COG2186	Transcriptional regulator
FY143_20135	COG0601	transmembrane transport
FY143_20145	COG0444	Belongs to the ABC transporter superfamily
FY143_20150	COG4608	Belongs to the ABC transporter superfamily
FY143_20170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20195	COG1473	amidohydrolase
FY143_20200	COG0747	negative chemotaxis
FY143_20220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20225	COG0583	DNA-binding transcription factor activity
FY143_20235	COG0667	Aldo Keto reductase
FY143_20245	COG0444	Belongs to the ABC transporter superfamily
FY143_20270	COG1960	acyl-CoA dehydrogenase activity
FY143_20290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY143_20305	COG1959	2 iron, 2 sulfur cluster binding
FY143_20310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20320	COG1473	amidohydrolase
FY143_20330	COG1126	abc transporter atp-binding protein
FY143_20335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_20350	COG1522	sequence-specific DNA binding
FY143_20355	COG4172	Belongs to the ABC transporter superfamily
FY143_20360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_20365	COG0601	transmembrane transport
FY143_20395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_20400	COG1012	belongs to the aldehyde dehydrogenase family
FY143_20405	COG0473	3-isopropylmalate dehydrogenase activity
FY143_20410	COG1012	belongs to the aldehyde dehydrogenase family
FY143_20425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY143_20445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_20450	COG1120	ATPase activity
FY143_20460	COG2226	methyltransferase
FY143_20475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_20480	COG1120	ATPase activity
FY143_20485	COG1595	DNA-templated transcription, initiation
FY143_20495	COG4771	TonB-dependent receptor
FY143_20505	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY143_20510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY143_20515	COG2197	response regulator
FY143_20520	COG0601	transmembrane transport
FY143_20525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_20545	COG0747	negative chemotaxis
FY143_20560	COG1446	asparaginase
FY143_20565	COG0583	DNA-binding transcription factor activity
FY143_20570	COG0601	transmembrane transport
FY143_20575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_20590	COG0747	negative chemotaxis
FY143_20595	COG1473	amidohydrolase
FY143_20605	COG1129	ABC transporter
FY143_20610	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_20615	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY143_20620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY143_20630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY143_20650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_20660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_20665	COG2079	MmgE PrpD family protein
FY143_20670	COG1126	abc transporter atp-binding protein
FY143_20675	COG0765	amino acid transport
FY143_20690	COG0280	phosphate acetyltransferase
FY143_20690	COG0281	malic enzyme
FY143_20695	COG0583	DNA-binding transcription factor activity
FY143_20720	COG1175	transmembrane transport
FY143_20725	COG0395	ABC-type sugar transport system, permease component
FY143_20740	COG0673	inositol 2-dehydrogenase activity
FY143_20745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY143_20750	COG0720	synthase
FY143_20755	COG0602	queuosine metabolic process
FY143_20760	COG0673	inositol 2-dehydrogenase activity
FY143_20770	COG3842	ATPase activity
FY143_20785	COG1653	transport
FY143_20790	COG1609	Transcriptional regulator
FY143_20800	COG2094	Belongs to the DNA glycosylase MPG family
FY143_20810	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_20820	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_20825	COG0840	transmembrane signaling receptor activity
FY143_20830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY143_20845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY143_20850	COG1596	polysaccharide export
FY143_20855	COG3307	-O-antigen
FY143_20895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_20920	COG2942	2-epimerase
FY143_20930	COG1215	transferase activity, transferring glycosyl groups
FY143_20950	COG1473	amidohydrolase
FY143_20960	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_20965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY143_20975	COG1301	dicarboxylic acid transport
FY143_20980	COG4191	Histidine kinase
FY143_20985	COG2204	response regulator
FY143_21000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_21005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY143_21010	COG1522	sequence-specific DNA binding
FY143_21015	COG0351	phosphomethylpyrimidine kinase
FY143_21020	COG0352	thiamine-phosphate diphosphorylase activity
FY143_21025	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY143_21030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY143_21035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_21045	COG1501	Belongs to the glycosyl hydrolase 31 family
FY143_21050	COG0395	ABC-type sugar transport system, permease component
FY143_21055	COG1175	transmembrane transport
FY143_21060	COG1653	transport
FY143_21065	COG3842	ATPase activity
FY143_21070	COG2188	Transcriptional regulator
FY143_21080	COG4989	oxidoreductase activity
FY143_21120	COG0438	transferase activity, transferring glycosyl groups
FY143_21130	COG0747	negative chemotaxis
FY143_21135	COG0601	transmembrane transport
FY143_21145	COG3964	amidohydrolase
FY143_21160	COG1921	L-seryl-tRNASec selenium transferase activity
FY143_21170	COG0625	glutathione transferase activity
FY143_21185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_21190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY143_21190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY143_21195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY143_21210	COG1312	Catalyzes the dehydration of D-mannonate
FY143_21215	COG1063	alcohol dehydrogenase
FY143_21220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY143_21230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY143_21235	COG2186	Transcriptional regulator
FY143_21240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY143_21245	COG0850	regulation of cytokinetic process
FY143_21250	COG2894	cell division
FY143_21255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY143_21270	COG5001	Diguanylate cyclase
FY143_21285	COG0673	inositol 2-dehydrogenase activity
FY143_21290	COG1940	carbohydrate kinase activity
FY143_21290	COG1846	Transcriptional regulator
FY143_21295	COG1653	transport
FY143_21300	COG1175	transmembrane transport
FY143_21305	COG0395	ABC-type sugar transport system, permease component
FY143_21310	COG3842	ATPase activity
FY143_21320	COG0673	inositol 2-dehydrogenase activity
FY143_21350	COG0587	DNA-directed DNA polymerase activity
FY143_21365	COG2186	Transcriptional regulator
FY143_21370	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_21375	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_21380	COG1129	ABC transporter
FY143_21385	COG1879	ABC-type sugar transport system periplasmic component
FY143_21390	COG0129	dihydroxy-acid dehydratase activity
FY143_21400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY143_21405	COG4608	Belongs to the ABC transporter superfamily
FY143_21410	COG0444	Belongs to the ABC transporter superfamily
FY143_21415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_21420	COG0601	transmembrane transport
FY143_21425	COG0747	negative chemotaxis
FY143_21435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY143_21440	COG5001	Diguanylate cyclase
FY143_21450	COG3257	ureidoglycine aminohydrolase activity
FY143_21455	COG3447	MASE1 domain protein
FY143_21455	COG5001	Diguanylate cyclase
FY143_21455	COG5002	protein histidine kinase activity
FY143_21460	COG1129	ABC transporter
FY143_21465	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_21470	COG1879	ABC-type sugar transport system periplasmic component
FY143_21475	COG0583	DNA-binding transcription factor activity
FY143_21500	COG3047	cAMP biosynthetic process
FY143_21510	COG3842	ATPase activity
FY143_21515	COG0395	ABC-type sugar transport system, permease component
FY143_21520	COG1175	transmembrane transport
FY143_21525	COG1653	transport
FY143_21530	COG0523	cobalamin synthesis protein
FY143_21545	COG0523	cobalamin synthesis protein
FY143_21550	COG1121	(ABC) transporter
FY143_21560	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY143_21570	COG0626	cystathionine gamma-synthase activity
FY143_21575	COG2182	Extracellular solute-binding protein
FY143_21585	COG0395	ABC-type sugar transport system, permease component
FY143_21600	COG0395	ABC-type sugar transport system, permease component
FY143_21605	COG1175	transmembrane transport
FY143_21610	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY143_21615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY143_21625	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_21630	COG1063	alcohol dehydrogenase
FY143_21635	COG1609	Transcriptional regulator
FY143_21650	COG2084	Dehydrogenase
FY143_21655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY143_21665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY143_21670	COG0583	DNA-binding transcription factor activity
FY143_21675	COG2223	nitrite transmembrane transporter activity
FY143_21710	COG0667	Aldo Keto reductase
FY143_21725	COG2186	Transcriptional regulator
FY143_21730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_21735	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY143_21740	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_21745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_21750	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_21755	COG3618	amidohydrolase
FY143_21760	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY143_21780	COG1175	transmembrane transport
FY143_21785	COG0395	ABC-type sugar transport system, permease component
FY143_21790	COG3842	ATPase activity
FY143_21805	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY143_21810	COG2205	protein histidine kinase activity
FY143_21830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY143_21835	COG0577	efflux transmembrane transporter activity
FY143_21835	COG1136	(ABC) transporter
FY143_21840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY143_21870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY143_21880	COG1278	Cold shock
FY143_21885	COG0673	inositol 2-dehydrogenase activity
FY143_21900	COG0673	inositol 2-dehydrogenase activity
FY143_21905	COG1309	transcriptional regulator
FY143_21910	COG1653	transport
FY143_21915	COG1175	transmembrane transport
FY143_21920	COG0395	ABC-type sugar transport system, permease component
FY143_21925	COG3842	ATPase activity
FY143_21930	COG1082	Xylose isomerase domain protein TIM barrel
FY143_21945	COG1609	Transcriptional regulator
FY143_21975	COG1175	transmembrane transport
FY143_21980	COG0395	ABC-type sugar transport system, permease component
FY143_21985	COG1116	anion transmembrane transporter activity
FY143_21990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY143_21995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY143_22005	COG3842	ATPase activity
FY143_22010	COG0395	ABC-type sugar transport system, permease component
FY143_22015	COG1175	transmembrane transport
FY143_22020	COG1653	transport
FY143_22050	COG3284	Transcriptional regulator
FY143_22055	COG1063	alcohol dehydrogenase
FY143_22070	COG2186	Transcriptional regulator
FY143_22075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_22080	COG0765	amino acid transport
FY143_22085	COG0765	amino acid transport
FY143_22095	COG3842	ATPase activity
FY143_22105	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_22110	COG0395	ABC-type sugar transport system, permease component
FY143_22120	COG1595	DNA-templated transcription, initiation
FY143_22160	COG2186	Transcriptional regulator
FY143_22165	COG0747	negative chemotaxis
FY143_22170	COG0601	transmembrane transport
FY143_22175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_22180	COG0405	Gamma-glutamyltransferase
FY143_22190	COG5002	protein histidine kinase activity
FY143_22190	COG0784	Response regulator, receiver
FY143_22190	COG2198	Histidine kinase
FY143_22210	COG1278	Cold shock
FY143_22230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_22235	COG0601	transmembrane transport
FY143_22240	COG0747	negative chemotaxis
FY143_22250	COG0583	DNA-binding transcription factor activity
FY143_22270	COG0583	DNA-binding transcription factor activity
FY143_22275	COG0477	Major facilitator Superfamily
FY143_22290	COG1522	sequence-specific DNA binding
FY143_22320	COG0747	negative chemotaxis
FY143_22325	COG0601	transmembrane transport
FY143_22330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_22335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_22365	COG3842	ATPase activity
FY143_22370	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_22375	COG1177	transmembrane transport
FY143_22380	COG4303	Ethanolamine ammonia lyase large subunit
FY143_22390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY143_22400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY143_22410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY143_22430	COG4178	(ABC) transporter
FY143_22470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY143_22495	COG2197	response regulator
FY143_22500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY143_22505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY143_22515	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY143_22520	COG4310	Domain of unknown function (DUF2172)
FY143_22525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY143_22530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY143_22535	COG2197	response regulator
FY143_22570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY143_22590	COG0438	transferase activity, transferring glycosyl groups
FY143_22605	COG0071	Belongs to the small heat shock protein (HSP20) family
FY143_22615	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_22625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY143_22635	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_22645	COG1653	transport
FY143_22650	COG0395	ABC-type sugar transport system, permease component
FY143_22655	COG4209	transmembrane transport
FY143_22660	COG3842	ATPase activity
FY143_22665	COG1802	Transcriptional regulator
FY143_22670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_22685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_22690	COG0765	amino acid transport
FY143_22700	COG1126	abc transporter atp-binding protein
FY143_22705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY143_22710	COG1027	Aspartate ammonia-lyase
FY143_22720	COG4172	Belongs to the ABC transporter superfamily
FY143_22725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_22730	COG0601	transmembrane transport
FY143_22735	COG0747	negative chemotaxis
FY143_22770	COG1522	sequence-specific DNA binding
FY143_22790	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_22795	COG0318	PFAM AMP-dependent synthetase and ligase
FY143_22805	COG1414	Transcriptional regulator
FY143_22815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY143_22825	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FY143_22835	COG1764	response to oxidative stress
FY143_22860	COG0596	Alpha beta hydrolase
FY143_22890	COG2814	Major facilitator Superfamily
FY143_22895	COG1162	GTPase activity
FY143_22935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FY143_22960	COG3547	Transposase (IS116 IS110 IS902 family)
FY143_23085	COG2161	toxin-antitoxin pair type II binding
FY143_23110	COG1192	Involved in chromosome partitioning
FY143_23115	COG1475	DNA binding
FY143_23120	COG0640	Transcriptional regulator
FY143_23145	COG0583	DNA-binding transcription factor activity
FY143_23195	COG3971	2-oxopent-4-enoate hydratase activity
FY143_23200	COG3485	protocatechuate 3,4-dioxygenase
FY143_23235	COG0535	radical SAM domain protein
FY143_23265	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_23275	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_23295	COG0583	DNA-binding transcription factor activity
FY143_23300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY143_23310	COG2169	Transcriptional regulator
FY143_23345	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_23360	COG0477	Major facilitator Superfamily
FY143_23365	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_23370	COG1794	racemase activity, acting on amino acids and derivatives
FY143_23380	COG0300	oxidoreductase activity
FY143_23395	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FY143_23400	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY143_23415	COG0287	Prephenate dehydrogenase
FY143_23415	COG1605	Chorismate mutase
FY143_23420	COG0583	DNA-binding transcription factor activity
FY143_23425	COG0300	oxidoreductase activity
FY143_23440	COG1376	ErfK ybiS ycfS ynhG family protein
FY143_23450	COG0251	oxidation-reduction process
FY143_23455	COG0154	amidase activity
FY143_23465	COG3620	sequence-specific DNA binding
FY143_23475	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY143_23480	COG3657	addiction module killer protein
FY143_23520	COG0395	ABC-type sugar transport system, permease component
FY143_23525	COG1175	transmembrane transport
FY143_23545	COG3220	belongs to the UPF0276 family
FY143_23570	COG5383	Protein conserved in bacteria
FY143_23575	COG1012	belongs to the aldehyde dehydrogenase family
FY143_23580	COG0436	Aminotransferase
FY143_23585	COG0247	lactate metabolic process
FY143_23585	COG0277	FAD linked oxidase domain protein
FY143_23590	COG0028	Belongs to the TPP enzyme family
FY143_23600	COG1126	abc transporter atp-binding protein
FY143_23605	COG0765	amino acid transport
FY143_23620	COG0583	DNA-binding transcription factor activity
FY143_23635	COG3609	addiction module antidote protein, CC2985 family
FY143_23650	COG2072	flavoprotein involved in K transport
FY143_23660	COG2144	transferase activity, transferring acyl groups
FY143_23670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY143_23685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY143_23695	COG0640	Transcriptional regulator
FY143_23755	COG2207	Transcriptional regulator
FY143_23770	COG0596	Alpha beta hydrolase
FY143_23800	COG1335	isochorismatase
FY143_23805	COG0596	Alpha beta hydrolase
FY143_23815	COG0596	Alpha beta hydrolase
FY143_23830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY143_23845	COG1959	2 iron, 2 sulfur cluster binding
FY143_23850	COG1309	transcriptional regulator
FY143_23855	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_23885	COG0840	transmembrane signaling receptor activity
FY143_23895	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_23920	COG0587	DNA-directed DNA polymerase activity
FY143_23940	COG5489	Protein of unknown function (DUF736)
FY143_23945	COG0776	regulation of translation
FY143_23950	COG3831	ATPase activity
FY143_23955	COG3505	Type IV secretory pathway VirD4
FY143_24020	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY143_24030	COG3842	ATPase activity
FY143_24035	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_24040	COG1177	transmembrane transport
FY143_24055	COG0577	efflux transmembrane transporter activity
FY143_24065	COG1414	Transcriptional regulator
FY143_24075	COG1454	alcohol dehydrogenase
FY143_24080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY143_24105	COG1285	pathogenesis
FY143_24115	COG0494	nUDIX hydrolase
FY143_24140	COG2945	thiolester hydrolase activity
FY143_24160	COG0529	Catalyzes the synthesis of activated sulfate
FY143_24190	COG3838	Conjugal transfer protein Trbc
FY143_24195	COG3702	type iv secretory pathway
FY143_24200	COG3451	type IV secretory pathway VirB4
FY143_24215	COG3704	protein secretion by the type IV secretion system
FY143_24225	COG3736	Type IV secretory pathway, component VirB8
FY143_24230	COG3504	Conjugal transfer protein
FY143_24235	COG2948	multi-organism process
FY143_24255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY143_24260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY143_24270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY143_24290	COG0784	Response regulator, receiver
FY143_24290	COG4191	Histidine kinase
FY143_24310	COG2072	flavoprotein involved in K transport
FY143_24330	COG3842	ATPase activity
FY143_24335	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_24345	COG2272	Belongs to the type-B carboxylesterase lipase family
FY143_24365	COG4691	Plasmid stability protein
FY143_24370	COG1487	ribonuclease activity
FY143_24375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_24385	COG2186	Transcriptional regulator
FY143_24390	COG0747	negative chemotaxis
FY143_24395	COG0601	transmembrane transport
FY143_24400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_24405	COG4172	Belongs to the ABC transporter superfamily
FY143_24410	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_24435	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY143_24440	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY143_24455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY143_24480	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY143_24485	COG3842	ATPase activity
FY143_24490	COG0483	inositol monophosphate 1-phosphatase activity
FY143_24495	COG0628	permease
FY143_24510	COG3734	2-keto-3-deoxy-galactonokinase
FY143_24515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY143_24520	COG4948	Mandelate Racemase Muconate Lactonizing
FY143_24530	COG1175	transmembrane transport
FY143_24535	COG0395	ABC-type sugar transport system, permease component
FY143_24540	COG3842	ATPase activity
FY143_24545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY143_24550	COG1414	Transcriptional regulator
FY143_24555	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_24560	COG2207	Transcriptional regulator
FY143_24580	COG1566	PFAM secretion protein HlyD family protein
FY143_24590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_24595	COG1120	ATPase activity
FY143_24605	COG4774	siderophore transport
FY143_24620	COG0583	DNA-binding transcription factor activity
FY143_24625	COG0667	Aldo Keto reductase
FY143_24635	COG0604	alcohol dehydrogenase
FY143_24640	COG1609	Transcriptional regulator
FY143_24645	COG1082	Xylose isomerase domain protein TIM barrel
FY143_24650	COG0673	inositol 2-dehydrogenase activity
FY143_24655	COG1082	Xylose isomerase domain protein TIM barrel
FY143_24665	COG0405	Gamma-glutamyltransferase
FY143_24670	COG1120	ATPase activity
FY143_24685	COG4774	siderophore transport
FY143_24705	COG1215	transferase activity, transferring glycosyl groups
FY143_24750	COG0840	transmembrane signaling receptor activity
FY143_24760	COG0156	8-amino-7-oxononanoate synthase activity
FY143_24765	COG2197	response regulator
FY143_24780	COG2390	Transcriptional regulator
FY143_24785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY143_24790	COG3958	Transketolase
FY143_24795	COG3959	Transketolase, thiamine diphosphate binding domain
FY143_24800	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_24810	COG1129	ABC transporter
FY143_24815	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_24820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY143_24830	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FY143_24850	COG0477	Major facilitator Superfamily
FY143_24870	COG1126	abc transporter atp-binding protein
FY143_24875	COG0765	amino acid transport
FY143_24880	COG0765	amino acid transport
FY143_24885	COG1741	Belongs to the pirin family
FY143_24890	COG1335	isochorismatase
FY143_24895	COG0583	DNA-binding transcription factor activity
FY143_24900	COG1733	regulation of RNA biosynthetic process
FY143_24905	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_24905	COG3321	synthase
FY143_24905	COG0604	alcohol dehydrogenase
FY143_24910	COG0583	DNA-binding transcription factor activity
FY143_24930	COG1017	nitric oxide dioxygenase activity
FY143_24930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY143_24935	COG0625	glutathione transferase activity
FY143_24945	COG0583	DNA-binding transcription factor activity
FY143_24970	COG1349	DNA-binding transcription factor activity
FY143_24975	COG1879	ABC-type sugar transport system periplasmic component
FY143_24980	COG1129	ABC transporter
FY143_24985	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_24990	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_25010	COG1012	belongs to the aldehyde dehydrogenase family
FY143_25015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY143_25055	COG4302	ethanolamine ammonia-lyase activity
FY143_25060	COG4303	Ethanolamine ammonia lyase large subunit
FY143_25080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY143_25085	COG1349	DNA-binding transcription factor activity
FY143_25090	COG4608	Belongs to the ABC transporter superfamily
FY143_25100	COG0601	transmembrane transport
FY143_25105	COG0747	negative chemotaxis
FY143_25110	COG3842	ATPase activity
FY143_25115	COG1063	alcohol dehydrogenase
FY143_25120	COG0395	ABC-type sugar transport system, permease component
FY143_25125	COG1175	transmembrane transport
FY143_25130	COG1653	transport
FY143_25155	COG0326	Molecular chaperone. Has ATPase activity
FY143_25165	COG1881	PFAM PEBP family protein
FY143_25175	COG1132	(ABC) transporter
FY143_25255	COG2801	Transposase and inactivated derivatives
FY143_25275	COG0583	DNA-binding transcription factor activity
FY143_25280	COG0667	Aldo Keto reductase
FY143_25315	COG1278	Cold shock
FY143_25330	COG1126	abc transporter atp-binding protein
FY143_25335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY143_25340	COG1609	Transcriptional regulator
FY143_25380	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY143_25385	COG0251	oxidation-reduction process
FY143_25390	COG3547	Transposase (IS116 IS110 IS902 family)
FY143_25425	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_25430	COG1335	isochorismatase
FY143_25440	COG1309	transcriptional regulator
FY143_25445	COG4604	ABC transporter, ATP-binding protein
FY143_25450	COG4605	iron ion homeostasis
FY143_25455	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY143_25465	COG2132	Multicopper oxidase
FY143_25470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY143_25475	COG4771	TonB-dependent receptor
FY143_25515	COG1695	Transcriptional regulator
FY143_25550	COG2132	Multicopper oxidase
FY143_25580	COG0583	DNA-binding transcription factor activity
FY143_25585	COG1741	Belongs to the pirin family
FY143_25590	COG1902	pentaerythritol trinitrate reductase activity
FY143_25600	COG1335	isochorismatase
FY143_25610	COG3344	reverse transcriptase
FY143_25645	COG3621	Patatin-like phospholipase
FY143_25650	COG1396	sequence-specific DNA binding
FY143_25660	COG0583	DNA-binding transcription factor activity
FY143_25665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_25670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_25675	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FY143_25680	COG0601	transmembrane transport
FY143_25685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_25690	COG4172	Belongs to the ABC transporter superfamily
FY143_25695	COG0747	negative chemotaxis
FY143_25715	COG1129	ABC transporter
FY143_25720	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY143_25730	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY143_25755	COG4716	Myosin-crossreactive antigen
FY143_25760	COG1196	nuclear chromosome segregation
FY143_25780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY143_25795	COG0583	DNA-binding transcription factor activity
FY143_25845	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY143_25855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY143_25900	COG1192	Involved in chromosome partitioning
FY143_25905	COG1475	DNA binding
FY143_25910	COG1414	Transcriptional regulator
FY143_25970	COG1475	DNA binding
FY143_26010	COG4227	nucleotidyltransferase activity
FY143_26030	COG5489	Protein of unknown function (DUF736)
FY143_26035	COG0776	regulation of translation
FY143_26040	COG3831	ATPase activity
FY143_26065	COG1733	regulation of RNA biosynthetic process
FY143_26080	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_26105	COG3451	type IV secretory pathway VirB4
FY143_26110	COG1196	nuclear chromosome segregation
FY143_26110	COG0741	lytic transglycosylase activity
FY143_26110	COG0739	heme binding
FY143_26140	COG2948	multi-organism process
FY143_26145	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY143_26210	COG1192	Involved in chromosome partitioning
FY143_26250	COG2801	Transposase and inactivated derivatives
FY143_26255	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY143_26260	COG1942	4-Oxalocrotonate Tautomerase
FY143_26270	COG3971	2-oxopent-4-enoate hydratase activity
FY143_26280	COG1414	Transcriptional regulator
FY143_26305	COG4177	L-phenylalanine transmembrane transporter activity
FY143_26335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY143_26340	COG1175	transmembrane transport
FY143_26345	COG0395	ABC-type sugar transport system, permease component
FY143_26350	COG1940	carbohydrate kinase activity
FY143_26355	COG0366	Alpha amylase catalytic
FY143_26360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY143_26370	COG3842	ATPase activity
FY143_26380	COG1940	carbohydrate kinase activity
FY143_26385	COG0395	ABC-type sugar transport system, permease component
FY143_26400	COG0673	inositol 2-dehydrogenase activity
FY143_26430	COG1126	abc transporter atp-binding protein
FY143_26435	COG0765	amino acid transport
FY143_26440	COG0765	amino acid transport
FY143_26450	COG4608	Belongs to the ABC transporter superfamily
FY143_26460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_26475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY143_26480	COG0583	DNA-binding transcription factor activity
FY143_26485	COG2423	ornithine cyclodeaminase activity
FY143_26495	COG1957	nucleoside hydrolase
FY143_26505	COG1309	transcriptional regulator
FY143_26515	COG1335	isochorismatase
FY143_26520	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_26565	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_26645	COG0583	DNA-binding transcription factor activity
FY143_26650	COG1902	pentaerythritol trinitrate reductase activity
FY143_26655	COG0583	DNA-binding transcription factor activity
FY143_26660	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_26670	COG1335	isochorismatase
FY143_26675	COG0583	DNA-binding transcription factor activity
FY143_26740	COG0196	riboflavin kinase activity
FY143_26795	COG3547	Transposase (IS116 IS110 IS902 family)
FY143_26805	COG3415	Transposase
FY143_26820	COG0583	DNA-binding transcription factor activity
FY143_26830	COG1741	Belongs to the pirin family
FY143_26835	COG1902	pentaerythritol trinitrate reductase activity
FY143_26845	COG1028	Short-chain dehydrogenase reductase Sdr
FY143_26860	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY143_26880	COG0747	negative chemotaxis
FY143_26890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_26905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY143_26915	COG4215	(ABC) transporter
FY143_26935	COG1192	Involved in chromosome partitioning
FY143_26940	COG1475	DNA binding
FY143_26945	COG0640	Transcriptional regulator
FY143_26950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY143_26965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY143_27100	COG1475	DNA binding
FY143_27110	COG0583	DNA-binding transcription factor activity
FY143_27135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY143_27170	COG5489	Protein of unknown function (DUF736)
FY143_27210	COG5489	Protein of unknown function (DUF736)
FY143_27295	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY143_27310	COG0747	negative chemotaxis
FY143_27330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_27335	COG0584	glycerophosphoryl diester phosphodiesterase
FY143_27340	COG0483	inositol monophosphate 1-phosphatase activity
FY143_27355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY143_27370	COG4974	Belongs to the 'phage' integrase family
FY143_27425	COG3436	PFAM IS66 Orf2 family protein
FY143_27430	COG4372	Transposase
FY143_27460	COG3161	chorismate lyase activity
FY143_27610	COG3436	PFAM IS66 Orf2 family protein
FY143_27700	COG4172	Belongs to the ABC transporter superfamily
FY143_27705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY143_27735	COG0583	DNA-binding transcription factor activity
FY143_27740	COG0747	negative chemotaxis
FY143_27755	COG0252	asparaginase activity
FY143_27760	COG0583	DNA-binding transcription factor activity
FY143_27780	COG3842	ATPase activity
FY143_27805	COG3701	Conjugal transfer protein
FY143_27810	COG3846	protein secretion by the type IV secretion system
FY143_27820	COG5314	conjugation
FY143_27825	COG3451	type IV secretory pathway VirB4
FY143_27840	COG4962	Type ii secretion system protein e
FY143_27850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY143_27920	COG1475	DNA binding
FY143_27935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs