locus-tag	class	description
FY144_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY144_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY144_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY144_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY144_00025	COG1420	regulation of RNA biosynthetic process
FY144_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY144_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY144_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY144_00050	COG1137	ATPase activity
FY144_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY144_00065	COG0616	signal peptide processing
FY144_00070	COG0776	regulation of translation
FY144_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY144_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY144_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY144_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY144_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY144_00115	COG0728	peptidoglycan biosynthetic process
FY144_00125	COG0180	Tryptophanyl-tRNA synthetase
FY144_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY144_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY144_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY144_00165	COG1702	phosphate starvation-inducible protein PhoH
FY144_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY144_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY144_00185	COG1396	sequence-specific DNA binding
FY144_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY144_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY144_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_00210	COG0242	peptide deformylase activity
FY144_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY144_00220	COG0101	tRNA pseudouridine synthase activity
FY144_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY144_00235	COG2171	N-acyltransferase activity
FY144_00245	COG0840	transmembrane signaling receptor activity
FY144_00250	COG1957	nucleoside hydrolase
FY144_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY144_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY144_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY144_00295	COG0706	membrane insertase activity
FY144_00300	COG0594	ribonuclease P activity
FY144_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY144_00310	COG0840	transmembrane signaling receptor activity
FY144_00325	COG2226	methyltransferase
FY144_00330	COG3842	ATPase activity
FY144_00335	COG1175	transmembrane transport
FY144_00340	COG0395	ABC-type sugar transport system, permease component
FY144_00355	COG0427	acetyl-CoA hydrolase
FY144_00365	COG3938	Belongs to the proline racemase family
FY144_00370	COG0418	dihydroorotase activity
FY144_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY144_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY144_00400	COG0166	Belongs to the GPI family
FY144_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY144_00410	COG3842	ATPase activity
FY144_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY144_00425	COG4774	siderophore transport
FY144_00465	COG2815	serine threonine protein kinase
FY144_00465	COG0515	serine threonine protein kinase
FY144_00520	COG2326	polyphosphate kinase activity
FY144_00525	COG5002	protein histidine kinase activity
FY144_00530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY144_00535	COG0573	inorganic phosphate transmembrane transporter activity
FY144_00545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY144_00550	COG0704	Plays a role in the regulation of phosphate uptake
FY144_00555	COG0745	RESPONSE REGULATOR receiver
FY144_00565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY144_00570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY144_00580	COG2967	ApaG domain
FY144_00595	COG0717	Belongs to the dCTP deaminase family
FY144_00605	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY144_00610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY144_00660	COG0167	dihydroorotate dehydrogenase activity
FY144_00675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_00695	COG1959	2 iron, 2 sulfur cluster binding
FY144_00700	COG1201	RNA secondary structure unwinding
FY144_00730	COG1960	acyl-CoA dehydrogenase activity
FY144_00735	COG0183	Belongs to the thiolase family
FY144_00740	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY144_00740	COG1024	Enoyl-CoA hydratase
FY144_00765	COG1320	monovalent cation:proton antiporter activity
FY144_00770	COG2212	antiporter activity
FY144_00775	COG1863	multisubunit Na H antiporter MnhE subunit
FY144_00780	COG0651	ATP synthesis coupled electron transport
FY144_00785	COG1006	Multisubunit Na H antiporter MnhC subunit
FY144_00790	COG2111	Na H antiporter
FY144_00790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY144_00800	COG0840	transmembrane signaling receptor activity
FY144_00810	COG0745	RESPONSE REGULATOR receiver
FY144_00815	COG0643	Histidine kinase
FY144_00815	COG2198	Histidine kinase
FY144_00820	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY144_00825	COG2201	protein-glutamate methylesterase activity
FY144_00830	COG0745	RESPONSE REGULATOR receiver
FY144_00835	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY144_00845	COG1766	The M ring may be actively involved in energy transduction
FY144_00850	COG2771	luxR family
FY144_00860	COG0840	transmembrane signaling receptor activity
FY144_00860	COG2972	Histidine kinase
FY144_00865	COG0784	Response regulator, receiver
FY144_00865	COG2198	Histidine kinase
FY144_00865	COG2205	protein histidine kinase activity
FY144_00870	COG1970	mechanosensitive ion channel activity
FY144_00875	COG0436	Aminotransferase
FY144_00890	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY144_00895	COG0424	maF-like protein
FY144_00900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY144_00910	COG5328	Belongs to the UPF0262 family
FY144_00915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY144_00925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY144_00945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY144_00955	COG1338	Plays a role in the flagellum-specific transport system
FY144_00965	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY144_00975	COG1706	bacterial-type flagellum-dependent cell motility
FY144_00980	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY144_00985	COG4786	Flagellar basal body rod
FY144_00990	COG1677	Flagellar hook-basal body complex protein FliE
FY144_00995	COG1558	bacterial-type flagellum-dependent cell motility
FY144_01000	COG1815	bacterial-type flagellum-dependent cell motility
FY144_01010	COG1157	protein secretion by the type III secretion system
FY144_01015	COG4786	Flagellar basal body rod
FY144_01025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY144_01030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY144_01035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY144_01040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY144_01045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY144_01065	COG1360	Flagellar Motor Protein
FY144_01110	COG5443	negative regulation of bacterial-type flagellum assembly
FY144_01115	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY144_01125	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY144_01165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY144_01170	COG1609	Transcriptional regulator
FY144_01175	COG1653	transport
FY144_01180	COG1175	transmembrane transport
FY144_01185	COG0395	ABC-type sugar transport system, permease component
FY144_01190	COG0366	Alpha amylase catalytic
FY144_01195	COG3842	ATPase activity
FY144_01210	COG0129	dihydroxy-acid dehydratase activity
FY144_01215	COG0363	glucosamine-6-phosphate deaminase activity
FY144_01220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY144_01225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_01235	COG2081	HI0933 family
FY144_01255	COG2224	Isocitrate lyase
FY144_01270	COG3842	ATPase activity
FY144_01275	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_01280	COG1177	transmembrane transport
FY144_01290	COG2205	protein histidine kinase activity
FY144_01300	COG0248	Ppx GppA phosphatase
FY144_01305	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY144_01310	COG0477	Major facilitator Superfamily
FY144_01340	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY144_01345	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY144_01355	COG0142	geranyltranstransferase activity
FY144_01380	COG0752	glycyl-tRNA synthetase alpha subunit
FY144_01390	COG1704	LemA family
FY144_01395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY144_01405	COG0751	glycine-tRNA ligase activity
FY144_01410	COG1683	Conserved Protein
FY144_01415	COG0840	transmembrane signaling receptor activity
FY144_01425	COG0151	Belongs to the GarS family
FY144_01430	COG2183	response to ionizing radiation
FY144_01435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY144_01460	COG0583	DNA-binding transcription factor activity
FY144_01480	COG0306	phosphate transporter
FY144_01490	COG0561	phosphatase activity
FY144_01495	COG0438	transferase activity, transferring glycosyl groups
FY144_01500	COG2186	Transcriptional regulator
FY144_01510	COG0583	DNA-binding transcription factor activity
FY144_01515	COG0277	FAD linked oxidase domain protein
FY144_01525	COG0247	lactate metabolic process
FY144_01535	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_01540	COG2818	Glycosylase
FY144_01550	COG2855	membrane
FY144_01555	COG0583	DNA-binding transcription factor activity
FY144_01585	COG0124	histidyl-tRNA synthetase
FY144_01595	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY144_01600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY144_01605	COG2259	Doxx family
FY144_01615	COG0459	protein refolding
FY144_01620	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY144_01630	COG0196	riboflavin kinase activity
FY144_01635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY144_01645	COG0590	tRNA wobble adenosine to inosine editing
FY144_01650	COG1187	pseudouridine synthase activity
FY144_01655	COG0742	ribosomal rna small subunit methyltransferase
FY144_01660	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY144_01670	COG0312	modulator of DNA gyrase
FY144_01675	COG0483	inositol monophosphate 1-phosphatase activity
FY144_01685	COG1519	Transferase
FY144_01695	COG1663	tetraacyldisaccharide 4'-kinase activity
FY144_01710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY144_01715	COG0745	RESPONSE REGULATOR receiver
FY144_01720	COG5001	Diguanylate cyclase
FY144_01720	COG3300	MHYT domain
FY144_01725	COG3386	PFAM SMP-30 Gluconolaconase
FY144_01730	COG0800	Aldolase
FY144_01735	COG3734	2-keto-3-deoxy-galactonokinase
FY144_01740	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_01745	COG1414	Transcriptional regulator
FY144_01750	COG2197	response regulator
FY144_01765	COG0598	Magnesium transport protein CorA
FY144_01770	COG3158	transport of potassium into the cell
FY144_01785	COG0356	it plays a direct role in the translocation of protons across the membrane
FY144_01795	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY144_01800	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY144_01815	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY144_01835	COG0009	L-threonylcarbamoyladenylate synthase
FY144_01845	COG4638	Rieske (2fe-2S)
FY144_01870	COG1960	acyl-CoA dehydrogenase activity
FY144_01885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY144_01890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY144_01895	COG0840	transmembrane signaling receptor activity
FY144_01905	COG1522	sequence-specific DNA binding
FY144_01930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY144_01935	COG1741	Belongs to the pirin family
FY144_01940	COG1722	exodeoxyribonuclease VII activity
FY144_01945	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY144_01950	COG1268	BioY protein
FY144_01955	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY144_01960	COG1122	ATPase activity
FY144_01965	COG3214	Protein conserved in bacteria
FY144_01970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_01970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_01975	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY144_01995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY144_02010	COG0259	pyridoxamine-phosphate oxidase activity
FY144_02040	COG0312	modulator of DNA gyrase
FY144_02055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_02060	COG0109	protoheme IX farnesyltransferase activity
FY144_02065	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY144_02080	COG3346	SURF1 family
FY144_02085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY144_02090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY144_02095	COG0328	RNA-DNA hybrid ribonuclease activity
FY144_02105	COG0678	peroxiredoxin activity
FY144_02105	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY144_02115	COG1678	Uncharacterized ACR, COG1678
FY144_02120	COG3237	CsbD-like
FY144_02130	COG3300	MHYT domain
FY144_02130	COG5001	Diguanylate cyclase
FY144_02135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY144_02140	COG0612	Peptidase, M16
FY144_02165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY144_02170	COG1802	Transcriptional regulator
FY144_02185	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY144_02190	COG3609	addiction module antidote protein, CC2985 family
FY144_02195	COG3668	Plasmid stabilization system
FY144_02205	COG1194	a g-specific adenine glycosylase
FY144_02220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY144_02225	COG1196	nuclear chromosome segregation
FY144_02230	COG2514	catechol 2,3-dioxygenase activity
FY144_02235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY144_02235	COG0574	Belongs to the PEP-utilizing enzyme family
FY144_02250	COG1823	symporter activity
FY144_02280	COG0579	oxidoreductase
FY144_02295	COG2895	sulfate adenylyltransferase (ATP) activity
FY144_02300	COG0175	sulfate reduction
FY144_02305	COG0175	sulfate reduction
FY144_02310	COG1959	2 iron, 2 sulfur cluster binding
FY144_02315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY144_02320	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY144_02325	COG4208	sulfate ABC transporter
FY144_02330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY144_02340	COG2200	EAL domain
FY144_02340	COG2203	Gaf domain
FY144_02340	COG2199	diguanylate cyclase activity
FY144_02350	COG1309	transcriptional regulator
FY144_02355	COG1012	belongs to the aldehyde dehydrogenase family
FY144_02360	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY144_02395	COG0625	glutathione transferase activity
FY144_02405	COG0477	Major facilitator Superfamily
FY144_02415	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY144_02415	COG1793	dna ligase
FY144_02435	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_02440	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_02445	COG1846	Transcriptional regulator
FY144_02450	COG1764	response to oxidative stress
FY144_02465	COG0488	(ABC) transporter
FY144_02500	COG4221	oxidoreductase activity
FY144_02515	COG0433	COG0433 Predicted ATPase
FY144_02525	COG1733	regulation of RNA biosynthetic process
FY144_02530	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY144_02545	COG0656	L-ascorbic acid biosynthetic process
FY144_02550	COG3781	membrane
FY144_02555	COG2378	regulation of single-species biofilm formation
FY144_02565	COG4106	trans-aconitate 2-methyltransferase activity
FY144_02570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY144_02575	COG0840	transmembrane signaling receptor activity
FY144_02580	COG0583	DNA-binding transcription factor activity
FY144_02595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY144_02615	COG3909	cytochrome
FY144_02620	COG2010	Cytochrome c
FY144_02650	COG0789	Transcriptional regulator
FY144_02675	COG0517	IMP dehydrogenase activity
FY144_02675	COG4175	Glycine betaine
FY144_02680	COG4176	ABC-type proline glycine betaine transport system permease component
FY144_02700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_02710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY144_02710	COG2169	Transcriptional regulator
FY144_02720	COG2514	catechol 2,3-dioxygenase activity
FY144_02740	COG1272	protein, Hemolysin III
FY144_02750	COG1280	lysine exporter protein (LysE YggA)
FY144_02755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY144_02760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY144_02760	COG2111	Na H antiporter
FY144_02765	COG2111	Na H antiporter
FY144_02770	COG1006	Multisubunit Na H antiporter MnhC subunit
FY144_02775	COG0651	ATP synthesis coupled electron transport
FY144_02780	COG1863	multisubunit Na H antiporter MnhE subunit
FY144_02785	COG2212	antiporter activity
FY144_02790	COG1320	monovalent cation:proton antiporter activity
FY144_02795	COG4957	zinc ion binding
FY144_02810	COG2166	iron-sulfur cluster assembly
FY144_02820	COG2205	protein histidine kinase activity
FY144_02860	COG0583	DNA-binding transcription factor activity
FY144_02865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY144_02870	COG2983	Belongs to the UPF0260 family
FY144_02880	COG3041	Addiction module toxin RelE StbE family
FY144_02885	COG3077	Addiction module antitoxin, RelB DinJ family
FY144_02890	COG2217	Heavy metal translocating P-type atpase
FY144_02920	COG2814	Major facilitator Superfamily
FY144_02925	COG1621	beta-fructofuranosidase activity
FY144_02930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY144_02980	COG4695	Portal protein
FY144_03085	COG4235	cytochrome complex assembly
FY144_03090	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY144_03095	COG1138	Cytochrome C-type biogenesis protein
FY144_03100	COG3088	subunit of a heme lyase
FY144_03105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_03110	COG0745	RESPONSE REGULATOR receiver
FY144_03115	COG2205	protein histidine kinase activity
FY144_03120	COG3011	Protein conserved in bacteria
FY144_03125	COG3713	MltA-interacting MipA family protein
FY144_03130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY144_03135	COG2202	Pas domain
FY144_03135	COG2205	protein histidine kinase activity
FY144_03145	COG0308	aminopeptidase N
FY144_03150	COG0697	spore germination
FY144_03165	COG0443	Heat shock 70 kDa protein
FY144_03200	COG0604	alcohol dehydrogenase
FY144_03205	COG1733	regulation of RNA biosynthetic process
FY144_03210	COG1968	undecaprenyl-diphosphatase activity
FY144_03215	COG2239	Acts as a magnesium transporter
FY144_03220	COG2814	Major facilitator Superfamily
FY144_03245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY144_03270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY144_03310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FY144_03315	COG0741	lytic transglycosylase activity
FY144_03320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_03325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY144_03330	COG0840	transmembrane signaling receptor activity
FY144_03340	COG1758	RNA polymerase activity
FY144_03360	COG0736	holo-[acyl-carrier-protein] synthase activity
FY144_03365	COG0681	Belongs to the peptidase S26 family
FY144_03370	COG0571	ribonuclease III activity
FY144_03375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY144_03385	COG0784	Response regulator, receiver
FY144_03390	COG1381	Involved in DNA repair and RecF pathway recombination
FY144_03400	COG2226	methyltransferase
FY144_03405	COG0633	Ferredoxin
FY144_03405	COG3217	Mosc domain protein beta barrel domain protein
FY144_03410	COG1418	mRNA catabolic process
FY144_03420	COG0346	lactoylglutathione lyase activity
FY144_03435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_03440	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY144_03445	COG0668	transmembrane transport
FY144_03455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY144_03485	COG1742	UPF0060 membrane protein
FY144_03500	COG1183	phosphatidylcholine synthase activity
FY144_03505	COG0688	phosphatidylethanolamine metabolic process
FY144_03510	COG5265	(ABC) transporter
FY144_03550	COG2852	Protein conserved in bacteria
FY144_03555	COG0215	cysteine-tRNA ligase activity
FY144_03560	COG4221	oxidoreductase activity
FY144_03565	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY144_03570	COG1286	toxin biosynthetic process
FY144_03590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY144_03600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY144_03610	COG0305	Participates in initiation and elongation during chromosome replication
FY144_03630	COG0359	binds to the 23S rRNA
FY144_03640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY144_03645	COG0360	Binds together with S18 to 16S ribosomal RNA
FY144_03655	COG0667	Aldo Keto reductase
FY144_03660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY144_03670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_03675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY144_03685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY144_03690	COG1561	YicC-like family, N-terminal region
FY144_03695	COG0194	GDP metabolic process
FY144_03710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY144_03715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY144_03725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY144_03740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY144_03760	COG2203	Gaf domain
FY144_03760	COG4251	negative regulation of phosphorylation
FY144_03760	COG3706	GGDEF domain
FY144_03760	COG5001	Diguanylate cyclase
FY144_03765	COG3300	MHYT domain
FY144_03765	COG5001	Diguanylate cyclase
FY144_03770	COG4191	Histidine kinase
FY144_03775	COG4566	intracellular signal transduction
FY144_03785	COG0488	(ABC) transporter
FY144_03790	COG3706	GGDEF domain
FY144_03800	COG0105	UTP biosynthetic process
FY144_03820	COG0314	molybdopterin synthase activity
FY144_03830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY144_03835	COG0322	excinuclease ABC activity
FY144_03840	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_03865	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY144_03870	COG0243	molybdopterin cofactor binding
FY144_03895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY144_03900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY144_03910	COG0628	permease
FY144_03920	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY144_03925	COG0248	Ppx GppA phosphatase
FY144_03950	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY144_03960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY144_03965	COG0477	Major facilitator Superfamily
FY144_03970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY144_03980	COG0840	transmembrane signaling receptor activity
FY144_03985	COG0659	secondary active sulfate transmembrane transporter activity
FY144_03995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY144_04000	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY144_04010	COG0113	porphobilinogen synthase activity
FY144_04030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY144_04035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY144_04040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY144_04040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY144_04050	COG1280	lysine exporter protein (LysE YggA)
FY144_04055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY144_04060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY144_04065	COG2814	Major facilitator Superfamily
FY144_04070	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY144_04090	COG0416	fatty acid biosynthetic process
FY144_04095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY144_04100	COG0776	regulation of translation
FY144_04135	COG0601	transmembrane transport
FY144_04140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_04145	COG0444	Belongs to the ABC transporter superfamily
FY144_04155	COG0747	negative chemotaxis
FY144_04165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY144_04170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY144_04185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY144_04190	COG0583	DNA-binding transcription factor activity
FY144_04195	COG0737	Belongs to the 5'-nucleotidase family
FY144_04215	COG2897	thiosulfate sulfurtransferase activity
FY144_04230	COG0415	Belongs to the DNA photolyase family
FY144_04240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY144_04270	COG3932	Exopolysaccharide synthesis, ExoD
FY144_04275	COG1238	metal cluster binding
FY144_04350	COG1612	heme a metabolic process
FY144_04360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY144_04365	COG0010	Belongs to the arginase family
FY144_04370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY144_04375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY144_04385	COG1832	CoA-binding protein
FY144_04410	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_04415	COG2124	cytochrome p450
FY144_04420	COG2199	diguanylate cyclase activity
FY144_04425	COG0740	serine-type endopeptidase activity
FY144_04430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY144_04435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY144_04445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY144_04465	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_04470	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_04475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_04485	COG0649	NAD binding
FY144_04495	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY144_04500	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY144_04510	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY144_04515	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY144_04525	COG0713	ATP synthesis coupled electron transport
FY144_04540	COG1007	ATP synthesis coupled electron transport
FY144_04545	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY144_04545	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY144_04560	COG0442	prolyl-tRNA aminoacylation
FY144_04570	COG1136	(ABC) transporter
FY144_04585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY144_04605	COG0784	Response regulator, receiver
FY144_04615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY144_04620	COG0477	Major facilitator Superfamily
FY144_04635	COG0557	exoribonuclease II activity
FY144_04640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY144_04650	COG0758	DNA mediated transformation
FY144_04655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY144_04665	COG0540	Belongs to the ATCase OTCase family
FY144_04680	COG1960	acyl-CoA dehydrogenase activity
FY144_04685	COG0456	acetyltransferase
FY144_04705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY144_04710	COG2824	Alkylphosphonate utilization operon protein PhnA
FY144_04715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY144_04720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY144_04725	COG0154	amidase activity
FY144_04730	COG0456	acetyltransferase
FY144_04735	COG3811	Belongs to the UPF0386 family
FY144_04750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY144_04760	COG0456	acetyltransferase
FY144_04780	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY144_04785	COG0439	Biotin carboxylase
FY144_04790	COG0511	ligase activity, forming carbon-carbon bonds
FY144_04795	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY144_04805	COG0436	Aminotransferase
FY144_04825	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_04830	COG1530	ribonuclease E activity
FY144_04840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY144_04860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY144_04865	COG0384	phenazine biosynthesis protein PhzF
FY144_04885	COG0633	Ferredoxin
FY144_04900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY144_04905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY144_04915	COG3768	UPF0283 membrane protein
FY144_04920	COG3106	COG3106 Predicted ATPase
FY144_04950	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY144_04985	COG0537	adenosine 5'-monophosphoramidase activity
FY144_05010	COG0052	Belongs to the universal ribosomal protein uS2 family
FY144_05015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY144_05020	COG0528	UMP kinase activity
FY144_05025	COG0233	cytoplasmic translational termination
FY144_05030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY144_05040	COG0750	zinc metalloprotease
FY144_05045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY144_05050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY144_05055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY144_05060	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY144_05065	COG3494	Protein of unknown function (DUF1009)
FY144_05070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY144_05075	COG2186	Transcriptional regulator
FY144_05085	COG0765	amino acid transport
FY144_05090	COG0765	amino acid transport
FY144_05100	COG0372	Belongs to the citrate synthase family
FY144_05115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY144_05125	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY144_05130	COG0148	phosphopyruvate hydratase activity
FY144_05140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY144_05145	COG0022	dehydrogenase e1 component
FY144_05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY144_05150	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY144_05160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY144_05170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY144_05175	COG0697	spore germination
FY144_05190	COG2867	negative regulation of translational initiation
FY144_05195	COG1058	Belongs to the CinA family
FY144_05195	COG1546	Belongs to the CinA family
FY144_05200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY144_05200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY144_05210	COG3852	Histidine kinase
FY144_05215	COG2204	response regulator
FY144_05220	COG5000	phosphorelay sensor kinase activity
FY144_05225	COG2204	response regulator
FY144_05230	COG0569	domain protein
FY144_05235	COG1923	regulation of RNA biosynthetic process
FY144_05240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY144_05245	COG3956	TIGRFAM MazG family protein
FY144_05255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY144_05255	COG1648	precorrin-2 dehydrogenase activity
FY144_05295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY144_05295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY144_05300	COG0509	glycine decarboxylation via glycine cleavage system
FY144_05305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_05330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY144_05335	COG0564	pseudouridine synthase activity
FY144_05355	COG0251	oxidation-reduction process
FY144_05360	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY144_05370	COG1671	Belongs to the UPF0178 family
FY144_05385	COG0450	alkyl hydroperoxide reductase
FY144_05395	COG0625	glutathione transferase activity
FY144_05405	COG2801	Transposase and inactivated derivatives
FY144_05410	COG2826	transposase and inactivated derivatives, IS30 family
FY144_05415	COG0431	NADPH-dependent FMN reductase
FY144_05425	COG0798	PFAM Bile acid sodium symporter
FY144_05430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY144_05445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY144_05445	COG0321	lipoyl(octanoyl) transferase activity
FY144_05450	COG0084	hydrolase, TatD family'
FY144_05455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY144_05465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY144_05515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY144_05520	COG2095	MarC family integral membrane protein
FY144_05525	COG0517	IMP dehydrogenase activity
FY144_05525	COG0617	tRNA 3'-terminal CCA addition
FY144_05525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY144_05535	COG0629	single-stranded DNA binding
FY144_05540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY144_05550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY144_05570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY144_05575	COG1121	(ABC) transporter
FY144_05595	COG0667	Aldo Keto reductase
FY144_05605	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY144_05690	COG2239	Acts as a magnesium transporter
FY144_05695	COG0243	molybdopterin cofactor binding
FY144_05705	COG0242	peptide deformylase activity
FY144_05715	COG2202	Pas domain
FY144_05715	COG2205	protein histidine kinase activity
FY144_05725	COG0321	lipoyl(octanoyl) transferase activity
FY144_05730	COG1064	alcohol dehydrogenase
FY144_05760	COG1862	Preprotein translocase
FY144_05780	COG2124	cytochrome p450
FY144_05795	COG0596	Alpha beta hydrolase
FY144_05805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_05810	COG0626	cystathionine gamma-synthase activity
FY144_05815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_05820	COG4597	amino acid ABC transporter
FY144_05825	COG0765	amino acid transport
FY144_05830	COG1126	abc transporter atp-binding protein
FY144_05845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY144_05860	COG0436	Aminotransferase
FY144_05890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY144_05900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY144_05905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_05910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY144_05925	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY144_05930	COG1489	DNA binding
FY144_05935	COG0024	Methionine aminopeptidase
FY144_05955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY144_05980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY144_05985	COG0546	phosphoglycolate phosphatase activity
FY144_05995	COG0114	fumarate hydratase activity
FY144_06005	COG0504	CTP synthase activity
FY144_06015	COG0149	triose-phosphate isomerase activity
FY144_06025	COG0187	DNA topoisomerase II activity
FY144_06035	COG0740	serine-type endopeptidase activity
FY144_06045	COG0640	Transcriptional regulator
FY144_06050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY144_06055	COG0745	RESPONSE REGULATOR receiver
FY144_06080	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY144_06080	COG3264	Mechanosensitive ion channel
FY144_06145	COG1127	ABC transporter
FY144_06150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY144_06155	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_06165	COG0280	phosphate acetyltransferase
FY144_06165	COG0281	malic enzyme
FY144_06175	COG0778	Nitroreductase
FY144_06180	COG0823	Involved in the tonB-independent uptake of proteins
FY144_06195	COG1368	sulfuric ester hydrolase activity
FY144_06220	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY144_06240	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY144_06260	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY144_06275	COG0318	PFAM AMP-dependent synthetase and ligase
FY144_06285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY144_06285	COG0512	Glutamine amidotransferase of anthranilate synthase
FY144_06290	COG0343	queuine tRNA-ribosyltransferase activity
FY144_06295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY144_06310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY144_06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY144_06330	COG0134	indole-3-glycerol-phosphate synthase activity
FY144_06335	COG0315	cyclic pyranopterin monophosphate synthase activity
FY144_06340	COG0303	'Molybdopterin
FY144_06345	COG3706	GGDEF domain
FY144_06355	COG0475	glutathione-regulated potassium exporter activity
FY144_06355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY144_06365	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY144_06375	COG2814	Major facilitator Superfamily
FY144_06380	COG0746	molybdenum cofactor guanylyltransferase activity
FY144_06385	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY144_06390	COG0739	heme binding
FY144_06395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY144_06400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY144_06405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY144_06410	COG0805	protein transport
FY144_06415	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY144_06420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY144_06425	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY144_06430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY144_06435	COG1472	Belongs to the glycosyl hydrolase 3 family
FY144_06445	COG0018	arginyl-trna synthetase
FY144_06450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY144_06475	COG0525	valine-tRNA ligase activity
FY144_06485	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY144_06515	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY144_06520	COG1058	Belongs to the CinA family
FY144_06520	COG1546	Belongs to the CinA family
FY144_06525	COG0589	response to stress
FY144_06530	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY144_06540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY144_06550	COG0640	Transcriptional regulator
FY144_06555	COG1914	H( )-stimulated, divalent metal cation uptake system
FY144_06565	COG1132	(ABC) transporter
FY144_06570	COG0628	permease
FY144_06605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY144_06615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY144_06625	COG0302	gtp cyclohydrolase
FY144_06630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY144_06635	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY144_06645	COG0516	GMP reductase activity
FY144_06645	COG0517	IMP dehydrogenase activity
FY144_06680	COG1760	l-serine dehydratase
FY144_06720	COG0583	DNA-binding transcription factor activity
FY144_06735	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY144_06735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY144_06745	COG0347	Belongs to the P(II) protein family
FY144_06750	COG0174	glutamine synthetase
FY144_06780	COG0697	spore germination
FY144_06790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY144_06800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY144_06830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY144_06840	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY144_06845	COG2186	Transcriptional regulator
FY144_06855	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY144_06860	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY144_06865	COG3845	ABC transporter
FY144_06870	COG1183	phosphatidylcholine synthase activity
FY144_06875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_06880	COG0679	Auxin Efflux Carrier
FY144_06885	COG0785	Cytochrome C biogenesis protein
FY144_06905	COG1278	Cold shock
FY144_06990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_07085	COG3685	Protein conserved in bacteria
FY144_07100	COG0393	Putative heavy-metal-binding
FY144_07160	COG0616	signal peptide processing
FY144_07210	COG2815	serine threonine protein kinase
FY144_07210	COG0515	serine threonine protein kinase
FY144_07220	COG3237	CsbD-like
FY144_07230	COG0270	DNA (cytosine-5-)-methyltransferase activity
FY144_07260	COG1061	Type III restriction enzyme res subunit
FY144_07370	COG0582	viral genome integration into host DNA
FY144_07385	COG0577	efflux transmembrane transporter activity
FY144_07385	COG1136	(ABC) transporter
FY144_07390	COG0577	efflux transmembrane transporter activity
FY144_07390	COG1136	(ABC) transporter
FY144_07415	COG2151	metal-sulfur cluster biosynthetic enzyme
FY144_07420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY144_07425	COG0719	Fe-S assembly protein
FY144_07430	COG0396	ATPase activity
FY144_07435	COG0719	Fe-S assembly protein
FY144_07440	COG1104	cysteine desulfurase activity
FY144_07445	COG2945	thiolester hydrolase activity
FY144_07450	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY144_07455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY144_07465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY144_07470	COG2833	Protein of unknown function (DUF455)
FY144_07475	COG0739	heme binding
FY144_07480	COG0513	Belongs to the DEAD box helicase family
FY144_07505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY144_07515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY144_07520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY144_07525	COG0047	phosphoribosylformylglycinamidine synthase activity
FY144_07540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_07545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY144_07570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY144_07575	COG2814	Major facilitator Superfamily
FY144_07580	COG0483	inositol monophosphate 1-phosphatase activity
FY144_07585	COG0483	inositol monophosphate 1-phosphatase activity
FY144_07590	COG0037	tRNA processing
FY144_07595	COG2066	Belongs to the glutaminase family
FY144_07600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY144_07605	COG0861	Integral membrane protein TerC family
FY144_07620	COG1280	lysine exporter protein (LysE YggA)
FY144_07630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY144_07635	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY144_07645	COG0538	isocitrate dehydrogenase activity
FY144_07655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY144_07660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY144_07665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_07670	COG2313	pseudouridylate synthase activity
FY144_07680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_07685	COG4215	(ABC) transporter
FY144_07695	COG5425	PFAM Usg family protein
FY144_07705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_07710	COG1522	sequence-specific DNA binding
FY144_07715	COG1573	uracil-dna glycosylase
FY144_07725	COG2202	Pas domain
FY144_07725	COG2205	protein histidine kinase activity
FY144_07730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY144_07735	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY144_07740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY144_07755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_07760	COG0842	Transport permease protein
FY144_07765	COG1131	(ABC) transporter
FY144_07770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_07770	COG0730	response to heat
FY144_07790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY144_07795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY144_07815	COG0129	dihydroxy-acid dehydratase activity
FY144_07820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY144_07825	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY144_07835	COG3739	integral membrane protein
FY144_07845	COG0203	ribosomal protein L17
FY144_07850	COG0202	RNA polymerase activity
FY144_07855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY144_07860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY144_07865	COG0563	adenylate kinase activity
FY144_07870	COG0201	protein transport
FY144_07875	COG0200	Binds to the 23S rRNA
FY144_07880	COG1841	ribosomal large subunit assembly
FY144_07885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY144_07890	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY144_07895	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY144_07900	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY144_07905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY144_07910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY144_07915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY144_07920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY144_07925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY144_07930	COG0255	Belongs to the universal ribosomal protein uL29 family
FY144_07935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY144_07940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY144_07945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY144_07950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY144_07955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY144_07960	COG0089	rRNA binding
FY144_07965	COG0088	Forms part of the polypeptide exit tunnel
FY144_07970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY144_07975	COG0051	transcription antitermination factor activity, RNA binding
FY144_07980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY144_07985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY144_07990	COG0049	tRNA binding
FY144_07995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY144_08015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY144_08020	COG0085	RNA polymerase activity
FY144_08025	COG0222	ribosome binding
FY144_08030	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY144_08035	COG0081	regulation of translation
FY144_08040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY144_08050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY144_08060	COG1086	Polysaccharide biosynthesis protein
FY144_08065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY144_08070	COG0861	Integral membrane protein TerC family
FY144_08095	COG1132	(ABC) transporter
FY144_08100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY144_08120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY144_08155	COG0784	Response regulator, receiver
FY144_08155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_08155	COG2198	Histidine kinase
FY144_08155	COG2205	protein histidine kinase activity
FY144_08160	COG0784	Response regulator, receiver
FY144_08165	COG3920	Histidine kinase
FY144_08165	COG2202	Pas domain
FY144_08170	COG0784	Response regulator, receiver
FY144_08175	COG4251	negative regulation of phosphorylation
FY144_08190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY144_08195	COG1607	acyl-coa hydrolase
FY144_08215	COG2910	NAD(P)H-binding
FY144_08220	COG1733	regulation of RNA biosynthetic process
FY144_08235	COG0556	nucleotide-excision repair
FY144_08245	COG2382	esterase
FY144_08265	COG0484	heat shock protein binding
FY144_08285	COG3706	GGDEF domain
FY144_08305	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_08310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_08325	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY144_08335	COG2207	Transcriptional regulator
FY144_08340	COG1064	alcohol dehydrogenase
FY144_08345	COG1252	NADH dehydrogenase
FY144_08350	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY144_08355	COG2197	response regulator
FY144_08360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY144_08395	COG0656	L-ascorbic acid biosynthetic process
FY144_08410	COG0440	acetolactate synthase activity
FY144_08415	COG0028	Belongs to the TPP enzyme family
FY144_08430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY144_08435	COG3830	Belongs to the UPF0237 family
FY144_08435	COG0560	Phosphoserine phosphatase
FY144_08455	COG0330	HflC and HflK could
FY144_08460	COG0330	HflC and HflK could
FY144_08470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY144_08505	COG0277	FAD linked oxidase domain protein
FY144_08510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY144_08550	COG1335	isochorismatase
FY144_08575	COG2264	protein methyltransferase activity
FY144_08580	COG1999	signal sequence binding
FY144_08590	COG0835	chemotaxis
FY144_08600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY144_08605	COG0583	DNA-binding transcription factor activity
FY144_08615	COG1247	-acetyltransferase
FY144_08625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY144_08630	COG0497	DNA recombination
FY144_08635	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY144_08645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY144_08650	COG0849	cell division
FY144_08655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY144_08660	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY144_08665	COG0477	Major facilitator Superfamily
FY144_08675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY144_08680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY144_08685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY144_08695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY144_08700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY144_08710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY144_08725	COG0275	rRNA processing
FY144_08730	COG2001	Belongs to the MraZ family
FY144_08755	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY144_08785	COG4106	trans-aconitate 2-methyltransferase activity
FY144_08805	COG2226	methyltransferase
FY144_08815	COG2267	carboxylic ester hydrolase activity
FY144_08820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY144_08850	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_08855	COG2814	Major facilitator Superfamily
FY144_08890	COG1012	belongs to the aldehyde dehydrogenase family
FY144_08895	COG0174	glutamine synthetase
FY144_08900	COG0531	amino acid
FY144_08915	COG2182	Extracellular solute-binding protein
FY144_08930	COG3842	ATPase activity
FY144_08990	COG2968	Membrane
FY144_09000	COG0432	Pfam Uncharacterised protein family UPF0047
FY144_09015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY144_09020	COG0358	DNA primase activity
FY144_09040	COG0505	Belongs to the CarA family
FY144_09045	COG0534	Mate efflux family protein
FY144_09060	COG2321	neutral zinc metallopeptidase
FY144_09075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY144_09085	COG3706	GGDEF domain
FY144_09100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY144_09110	COG1522	sequence-specific DNA binding
FY144_09115	COG0492	ferredoxin-NADP+ reductase activity
FY144_09120	COG0583	DNA-binding transcription factor activity
FY144_09130	COG1902	pentaerythritol trinitrate reductase activity
FY144_09155	COG0387	Pfam Sodium calcium exchanger
FY144_09160	COG0436	Aminotransferase
FY144_09165	COG2200	EAL domain
FY144_09165	COG2199	diguanylate cyclase activity
FY144_09180	COG1278	Cold shock
FY144_09185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY144_09195	COG1846	Transcriptional regulator
FY144_09200	COG0745	RESPONSE REGULATOR receiver
FY144_09210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY144_09230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY144_09240	COG1496	oxidoreductase activity
FY144_09255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY144_09265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY144_09280	COG0840	transmembrane signaling receptor activity
FY144_09285	COG1012	belongs to the aldehyde dehydrogenase family
FY144_09290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY144_09295	COG3300	MHYT domain
FY144_09295	COG5001	Diguanylate cyclase
FY144_09300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY144_09305	COG5001	Diguanylate cyclase
FY144_09315	COG0193	aminoacyl-tRNA hydrolase activity
FY144_09325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY144_09350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY144_09360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY144_09360	COG2857	Cytochrome c1
FY144_09380	COG1132	(ABC) transporter
FY144_09385	COG1132	(ABC) transporter
FY144_09395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY144_09410	COG0408	coproporphyrinogen oxidase activity
FY144_09425	COG0617	tRNA 3'-terminal CCA addition
FY144_09440	COG0714	Associated with various cellular activities
FY144_09460	COG0454	-acetyltransferase
FY144_09475	COG0477	Major facilitator Superfamily
FY144_09485	COG0435	Glutathione S-transferase
FY144_09490	COG0494	nUDIX hydrolase
FY144_09505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY144_09510	COG3135	benzoate transporter
FY144_09535	COG0740	serine-type endopeptidase activity
FY144_09550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY144_09555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY144_09580	COG4175	Glycine betaine
FY144_09600	COG1435	thymidine kinase activity
FY144_09625	COG1629	transport
FY144_09625	COG4771	TonB-dependent receptor
FY144_09635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY144_09635	COG0512	Glutamine amidotransferase of anthranilate synthase
FY144_09650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY144_09660	COG0366	Alpha amylase catalytic
FY144_09665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_09685	COG1160	GTP binding
FY144_09705	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY144_09715	COG0024	Methionine aminopeptidase
FY144_09725	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_09735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY144_09745	COG0583	DNA-binding transcription factor activity
FY144_09765	COG0402	S-adenosylhomocysteine deaminase activity
FY144_09785	COG1309	transcriptional regulator
FY144_09790	COG1686	Belongs to the peptidase S11 family
FY144_09800	COG2351	hydroxyisourate hydrolase activity
FY144_09805	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY144_09820	COG3648	Uricase
FY144_09820	COG3195	allantoin biosynthetic process
FY144_09830	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY144_09840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_09840	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY144_09850	COG0513	Belongs to the DEAD box helicase family
FY144_09865	COG2259	Doxx family
FY144_09870	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_09880	COG2308	Evidence 4 Homologs of previously reported genes of
FY144_09890	COG1305	Transglutaminase-like
FY144_09920	COG4214	carbohydrate transport
FY144_09925	COG1129	ABC transporter
FY144_09930	COG4213	ABC transporter substrate-binding protein
FY144_10055	COG1410	methionine synthase
FY144_10055	COG0646	methionine synthase
FY144_10100	COG1215	transferase activity, transferring glycosyl groups
FY144_10130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY144_10155	COG1309	transcriptional regulator
FY144_10170	COG0494	nUDIX hydrolase
FY144_10180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_10185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_10215	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY144_10220	COG0830	nickel cation binding
FY144_10225	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY144_10240	COG0804	urea catabolic process
FY144_10245	COG1442	glycosyl transferase family 8
FY144_10255	COG0832	Belongs to the urease beta subunit family
FY144_10260	COG3813	Protein conserved in bacteria
FY144_10265	COG0831	urea catabolic process
FY144_10270	COG0829	nickel cation binding
FY144_10300	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY144_10315	COG0174	glutamine synthetase
FY144_10320	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_10325	COG0784	Response regulator, receiver
FY144_10325	COG2198	Histidine kinase
FY144_10325	COG5002	protein histidine kinase activity
FY144_10340	COG0726	polysaccharide deacetylase
FY144_10375	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY144_10450	COG0564	pseudouridine synthase activity
FY144_10460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY144_10470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY144_10495	COG0346	lactoylglutathione lyase activity
FY144_10505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY144_10515	COG2832	Protein of unknown function (DUF454)
FY144_10520	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY144_10525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_10530	COG4558	Periplasmic binding protein
FY144_10540	COG3721	Heme iron utilization protein
FY144_10555	COG3655	Transcriptional regulator
FY144_10570	COG3657	addiction module killer protein
FY144_10580	COG2205	protein histidine kinase activity
FY144_10625	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_10630	COG4605	iron ion homeostasis
FY144_10635	COG4604	ABC transporter, ATP-binding protein
FY144_10640	COG0783	Belongs to the Dps family
FY144_10655	COG2972	Histidine kinase
FY144_10655	COG0840	transmembrane signaling receptor activity
FY144_10660	COG0656	L-ascorbic acid biosynthetic process
FY144_10665	COG2814	Major facilitator Superfamily
FY144_10675	COG0583	DNA-binding transcription factor activity
FY144_10680	COG0657	acetylesterase activity
FY144_10685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_10705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY144_10710	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY144_10715	COG0288	reversible hydration of carbon dioxide
FY144_10725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY144_10745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY144_10750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY144_10755	COG0778	Nitroreductase
FY144_10760	COG2267	carboxylic ester hydrolase activity
FY144_10765	COG0251	oxidation-reduction process
FY144_10770	COG1335	isochorismatase
FY144_10775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_10785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_10800	COG1175	transmembrane transport
FY144_10805	COG0395	ABC-type sugar transport system, permease component
FY144_10810	COG3842	ATPase activity
FY144_10815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_10825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY144_10840	COG4608	Belongs to the ABC transporter superfamily
FY144_10845	COG0444	Belongs to the ABC transporter superfamily
FY144_10850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_10855	COG0601	transmembrane transport
FY144_10910	COG2159	amidohydrolase
FY144_10915	COG1960	acyl-CoA dehydrogenase activity
FY144_10945	COG0745	RESPONSE REGULATOR receiver
FY144_10955	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_10955	COG1902	pentaerythritol trinitrate reductase activity
FY144_10960	COG3842	ATPase activity
FY144_10970	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_10975	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_10980	COG0745	RESPONSE REGULATOR receiver
FY144_10990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY144_10995	COG0583	DNA-binding transcription factor activity
FY144_11000	COG1278	Cold shock
FY144_11005	COG4372	Transposase
FY144_11010	COG3436	PFAM IS66 Orf2 family protein
FY144_11050	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY144_11055	COG1309	transcriptional regulator
FY144_11060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_11065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY144_11075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY144_11080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY144_11100	COG0583	DNA-binding transcription factor activity
FY144_11105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_11110	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY144_11115	COG4149	molybdate abc transporter
FY144_11120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY144_11135	COG2022	thiamine diphosphate biosynthetic process
FY144_11150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY144_11160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_11170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY144_11190	COG1132	(ABC) transporter
FY144_11195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY144_11240	COG4166	transmembrane transport
FY144_11245	COG0601	transmembrane transport
FY144_11250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_11265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY144_11270	COG3142	Participates in the control of copper homeostasis
FY144_11275	COG2814	Major facilitator Superfamily
FY144_11290	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_11295	COG1737	Transcriptional regulator
FY144_11305	COG3842	ATPase activity
FY144_11315	COG0395	ABC-type sugar transport system, permease component
FY144_11335	COG2188	Transcriptional regulator
FY144_11340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY144_11345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY144_11350	COG1940	carbohydrate kinase activity
FY144_11360	COG0671	phosphoesterase, PA-phosphatase related
FY144_11365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY144_11370	COG0156	8-amino-7-oxononanoate synthase activity
FY144_11380	COG0729	surface antigen
FY144_11390	COG0835	chemotaxis
FY144_11400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY144_11405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY144_11410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY144_11415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY144_11420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY144_11425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY144_11440	COG4974	Belongs to the 'phage' integrase family
FY144_11465	COG1280	lysine exporter protein (LysE YggA)
FY144_11475	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY144_11480	COG0567	Dehydrogenase, E1 component
FY144_11485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY144_11490	COG0045	succinate-CoA ligase (ADP-forming) activity
FY144_11495	COG0039	L-malate dehydrogenase activity
FY144_11500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY144_11535	COG2264	protein methyltransferase activity
FY144_11550	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY144_11555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY144_11560	COG0181	hydroxymethylbilane synthase activity
FY144_11600	COG1872	DUF167
FY144_11605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY144_11615	COG1217	gtp-binding protein TYPA
FY144_11620	COG0339	signal peptide processing
FY144_11625	COG1846	Transcriptional regulator
FY144_11635	COG0137	argininosuccinate synthase activity
FY144_11645	COG1280	lysine exporter protein (LysE YggA)
FY144_11650	COG1122	ATPase activity
FY144_11655	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY144_11665	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY144_11680	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY144_11685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY144_11690	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY144_11700	COG4181	ATPase activity
FY144_11710	COG0670	Belongs to the BI1 family
FY144_11725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY144_11730	COG4133	protoheme IX ABC transporter activity
FY144_11735	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY144_11740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY144_11765	COG2917	probably involved in intracellular septation
FY144_11770	COG0552	protein localization to endoplasmic reticulum
FY144_11775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY144_11780	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY144_11795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY144_11800	COG0287	Prephenate dehydrogenase
FY144_11800	COG1605	Chorismate mutase
FY144_11805	COG0228	four-way junction DNA binding
FY144_11810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY144_11815	COG0336	Belongs to the RNA methyltransferase TrmD family
FY144_11825	COG0335	large ribosomal subunit rRNA binding
FY144_11830	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY144_11835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_11850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY144_11870	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY144_11890	COG0488	(ABC) transporter
FY144_11900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY144_11910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY144_11915	COG0142	geranyltranstransferase activity
FY144_11920	COG2885	chlorophyll binding
FY144_11925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY144_11930	COG2223	nitrite transmembrane transporter activity
FY144_11935	COG1349	DNA-binding transcription factor activity
FY144_11940	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY144_11945	COG2197	response regulator
FY144_11950	COG1132	(ABC) transporter
FY144_11960	COG3459	Glycosyltransferase 36 associated
FY144_11965	COG1473	amidohydrolase
FY144_11970	COG0579	oxidoreductase
FY144_11980	COG0129	dihydroxy-acid dehydratase activity
FY144_11985	COG2084	Dehydrogenase
FY144_11990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_11995	COG0277	FAD linked oxidase domain protein
FY144_12000	COG2186	Transcriptional regulator
FY144_12010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY144_12015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_12020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_12025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY144_12035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY144_12040	COG0495	leucyl-tRNA aminoacylation
FY144_12055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY144_12060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY144_12075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_12080	COG1946	Acyl-CoA thioesterase
FY144_12085	COG0347	Belongs to the P(II) protein family
FY144_12090	COG0004	ammonium transporteR
FY144_12095	COG1674	ftsk spoiiie
FY144_12100	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY144_12115	COG0745	RESPONSE REGULATOR receiver
FY144_12125	COG1329	Transcriptional regulator
FY144_12135	COG2270	Major facilitator Superfamily
FY144_12150	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_12165	COG0494	nUDIX hydrolase
FY144_12170	COG2861	carbohydrate metabolic process
FY144_12175	COG0793	Belongs to the peptidase S41A family
FY144_12185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY144_12190	COG0799	negative regulation of ribosome biogenesis
FY144_12195	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY144_12200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY144_12205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY144_12210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY144_12225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY144_12230	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY144_12255	COG0066	3-isopropylmalate dehydratase activity
FY144_12260	COG0473	3-isopropylmalate dehydrogenase activity
FY144_12265	COG1858	cytochrome C peroxidase
FY144_12270	COG1797	cobyrinic acid a,c-diamide synthase activity
FY144_12280	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY144_12345	COG1492	cobalamin metabolic process
FY144_12360	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_12365	COG3254	rhamnose metabolic process
FY144_12370	COG0246	Mannitol dehydrogenase
FY144_12375	COG1063	alcohol dehydrogenase
FY144_12400	COG1129	ABC transporter
FY144_12405	COG2186	Transcriptional regulator
FY144_12410	COG2721	sulfolactate sulfo-lyase activity
FY144_12415	COG0138	bifunctional purine biosynthesis protein purh
FY144_12425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY144_12425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY144_12430	COG0501	Belongs to the peptidase M48B family
FY144_12450	COG0357	Ribosomal RNA small subunit methyltransferase G
FY144_12455	COG0445	tRNA wobble uridine modification
FY144_12460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY144_12465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY144_12470	COG1981	membrane
FY144_12475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY144_12480	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY144_12485	COG0424	maF-like protein
FY144_12490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY144_12495	COG0237	dephospho-CoA kinase activity
FY144_12505	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY144_12510	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY144_12520	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY144_12545	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY144_12560	COG0135	phosphoribosylanthranilate isomerase activity
FY144_12565	COG0133	tryptophan synthase activity
FY144_12570	COG0159	tryptophan synthase activity
FY144_12575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY144_12590	COG1074	ATP-dependent DNA helicase activity
FY144_12600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY144_12605	COG0802	atpase or kinase
FY144_12610	COG2205	protein histidine kinase activity
FY144_12615	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY144_12620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY144_12625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY144_12625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY144_12630	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY144_12635	COG0642	Histidine kinase
FY144_12640	COG0745	RESPONSE REGULATOR receiver
FY144_12645	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY144_12655	COG1652	LysM domain
FY144_12660	COG1072	(Pantothenic acid kinase))
FY144_12665	COG0140	phosphoribosyl-ATP diphosphatase activity
FY144_12670	COG0107	imidazoleglycerol-phosphate synthase activity
FY144_12675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY144_12680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY144_12690	COG0131	Imidazoleglycerol-phosphate dehydratase
FY144_12695	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY144_12700	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY144_12710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY144_12725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY144_12735	COG1643	Atp-dependent helicase
FY144_12775	COG1940	carbohydrate kinase activity
FY144_12795	COG1072	(Pantothenic acid kinase))
FY144_12805	COG1780	Probably involved in ribonucleotide reductase function
FY144_12825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY144_12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_12865	COG2813	Specifically methylates the guanine in position
FY144_12870	COG1185	polyribonucleotide nucleotidyltransferase activity
FY144_12875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY144_12880	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY144_12885	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY144_12890	COG3064	Membrane
FY144_12890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY144_12905	COG0779	Required for maturation of 30S ribosomal subunits
FY144_12910	COG2814	Major facilitator Superfamily
FY144_12915	COG2951	lytic endotransglycosylase activity
FY144_12920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY144_12930	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY144_12935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY144_12950	COG2816	NAD+ diphosphatase activity
FY144_12955	COG1605	Chorismate mutase
FY144_12955	COG0077	Prephenate dehydratase
FY144_12960	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY144_12965	COG3474	cytochrome
FY144_12975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY144_12980	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY144_12985	COG1278	Cold shock
FY144_12990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY144_13000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY144_13000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY144_13005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY144_13035	COG2900	Belongs to the SlyX family
FY144_13045	COG0484	heat shock protein binding
FY144_13050	COG0443	Heat shock 70 kDa protein
FY144_13065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY144_13070	COG1744	ABC transporter substrate-binding protein PnrA-like
FY144_13075	COG3845	ABC transporter
FY144_13080	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY144_13085	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY144_13090	COG0295	cytidine deaminase activity
FY144_13095	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY144_13100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY144_13105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY144_13115	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY144_13120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY144_13125	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY144_13135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY144_13140	COG1845	cytochrome c oxidase, subunit III
FY144_13145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_13150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY144_13155	COG0477	Major facilitator Superfamily
FY144_13160	COG0067	glutamate synthase
FY144_13160	COG0069	glutamate synthase activity
FY144_13160	COG0070	glutamate synthase
FY144_13165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY144_13180	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY144_13190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY144_13220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_13240	COG0848	biopolymer transport protein
FY144_13250	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY144_13265	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY144_13270	COG3454	Phosphonate metabolism
FY144_13275	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY144_13280	COG3639	organic phosphonate transmembrane transporter activity
FY144_13285	COG3639	organic phosphonate transmembrane transporter activity
FY144_13290	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY144_13295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY144_13305	COG4778	phosphonate C-P lyase system protein PhnL
FY144_13310	COG4107	phosphonate C-P lyase system protein PhnK
FY144_13315	COG3627	carbon phosphorus lyase activity
FY144_13320	COG3626	phosphonate metabolism
FY144_13325	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY144_13330	COG3624	Phosphonate C-P lyase system protein PhnG
FY144_13335	COG2188	Transcriptional regulator
FY144_13340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY144_13345	COG0837	glucose binding
FY144_13350	COG1803	Methylglyoxal synthase
FY144_13355	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY144_13360	COG4166	transmembrane transport
FY144_13365	COG4174	ABC transporter (Permease)
FY144_13370	COG4239	(ABC) transporter, permease
FY144_13375	COG4172	Belongs to the ABC transporter superfamily
FY144_13380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_13385	COG0174	glutamine synthetase
FY144_13390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_13395	COG3265	gluconokinase activity
FY144_13400	COG1174	glycine betaine transport
FY144_13405	COG1125	glycine betaine transport
FY144_13410	COG1174	glycine betaine transport
FY144_13415	COG1732	Glycine betaine
FY144_13425	COG1959	2 iron, 2 sulfur cluster binding
FY144_13430	COG1840	ABC-type Fe3 transport system, periplasmic component
FY144_13435	COG0501	Belongs to the peptidase M48B family
FY144_13440	COG4269	membrane
FY144_13455	COG0697	spore germination
FY144_13470	COG0791	NLP P60 protein
FY144_13480	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY144_13485	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY144_13520	COG4964	Belongs to the GSP D family
FY144_13560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY144_13565	COG3422	double-strand break repair
FY144_13570	COG3757	hydrolase, family 25
FY144_13575	COG0697	spore germination
FY144_13580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_13595	COG0492	ferredoxin-NADP+ reductase activity
FY144_13610	COG0481	GTPase activity
FY144_13615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY144_13630	COG1396	sequence-specific DNA binding
FY144_13645	COG2169	Transcriptional regulator
FY144_13645	COG1917	Cupin 2, conserved barrel domain protein
FY144_13650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY144_13675	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY144_13680	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY144_13685	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY144_13695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY144_13700	COG0072	phenylalanine-tRNA ligase activity
FY144_13700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY144_13705	COG0667	Aldo Keto reductase
FY144_13725	COG4977	sequence-specific DNA binding
FY144_13750	COG1570	exodeoxyribonuclease VII activity
FY144_13755	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_13765	COG1846	Transcriptional regulator
FY144_13770	COG0697	spore germination
FY144_13775	COG2309	aminopeptidase activity
FY144_13785	COG1393	Belongs to the ArsC family
FY144_13800	COG1309	transcriptional regulator
FY144_13810	COG0519	Catalyzes the synthesis of GMP from XMP
FY144_13810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY144_13825	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY144_13855	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY144_13865	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY144_13875	COG1968	undecaprenyl-diphosphatase activity
FY144_13890	COG0284	orotidine-5'-phosphate decarboxylase activity
FY144_13900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY144_13910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY144_13915	COG0792	nuclease activity
FY144_13930	COG1175	transmembrane transport
FY144_13935	COG0395	ABC-type sugar transport system, permease component
FY144_13940	COG3842	ATPase activity
FY144_13950	COG0189	ligase activity
FY144_13955	COG0606	chelatase, subunit chli
FY144_13960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY144_13965	COG1280	lysine exporter protein (LysE YggA)
FY144_13970	COG0756	dUTP diphosphatase activity
FY144_13975	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY144_13980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY144_13995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY144_14000	COG2226	methyltransferase
FY144_14005	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY144_14010	COG1024	Enoyl-CoA hydratase
FY144_14015	COG0268	Binds directly to 16S ribosomal RNA
FY144_14025	COG2161	toxin-antitoxin pair type II binding
FY144_14060	COG2267	carboxylic ester hydrolase activity
FY144_14105	COG3436	PFAM IS66 Orf2 family protein
FY144_14110	COG4372	Transposase
FY144_14135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY144_14205	COG0668	transmembrane transport
FY144_14250	COG3706	GGDEF domain
FY144_14275	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_14290	COG2358	TRAP transporter, solute receptor (TAXI family
FY144_14305	COG1802	Transcriptional regulator
FY144_14310	COG3842	ATPase activity
FY144_14315	COG4209	transmembrane transport
FY144_14320	COG0395	ABC-type sugar transport system, permease component
FY144_14325	COG1653	transport
FY144_14335	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_14345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_14355	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_14385	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_14390	COG0625	glutathione transferase activity
FY144_14410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY144_14415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY144_14430	COG0534	Mate efflux family protein
FY144_14480	COG1278	Cold shock
FY144_14505	COG0640	Transcriptional regulator
FY144_14530	COG4297	protein containing double-stranded beta helix domain
FY144_14540	COG4178	(ABC) transporter
FY144_14560	COG0596	Alpha beta hydrolase
FY144_14565	COG0583	DNA-binding transcription factor activity
FY144_14575	COG0765	amino acid transport
FY144_14580	COG1126	abc transporter atp-binding protein
FY144_14585	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_14590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_14625	COG1522	sequence-specific DNA binding
FY144_14630	COG1012	belongs to the aldehyde dehydrogenase family
FY144_14635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_14640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_14645	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY144_14650	COG2423	ornithine cyclodeaminase activity
FY144_14655	COG0006	proline dipeptidase activity
FY144_14660	COG3608	succinylglutamate desuccinylase aspartoacylase
FY144_14665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_14670	COG0765	amino acid transport
FY144_14675	COG0765	amino acid transport
FY144_14680	COG1126	abc transporter atp-binding protein
FY144_14690	COG1082	Xylose isomerase domain protein TIM barrel
FY144_14695	COG0572	uridine kinase
FY144_14705	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_14710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_14715	COG1129	ABC transporter
FY144_14735	COG3284	Transcriptional regulator
FY144_14740	COG1063	alcohol dehydrogenase
FY144_14750	COG0110	maltose O-acetyltransferase activity
FY144_14755	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY144_14780	COG0488	(ABC) transporter
FY144_14785	COG1132	(ABC) transporter
FY144_14790	COG3181	Tripartite tricarboxylate transporter family receptor
FY144_14795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY144_14805	COG3237	CsbD-like
FY144_14830	COG3842	ATPase activity
FY144_14840	COG0483	inositol monophosphate 1-phosphatase activity
FY144_14850	COG0405	Gamma-glutamyltransferase
FY144_14855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_14860	COG0601	transmembrane transport
FY144_14865	COG0747	negative chemotaxis
FY144_14870	COG2186	Transcriptional regulator
FY144_14880	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_14885	COG4172	Belongs to the ABC transporter superfamily
FY144_14890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_14895	COG0601	transmembrane transport
FY144_14900	COG0747	negative chemotaxis
FY144_14905	COG2186	Transcriptional regulator
FY144_14915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_14920	COG2223	nitrite transmembrane transporter activity
FY144_14930	COG3383	formate dehydrogenase (NAD+) activity
FY144_14955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_14965	COG0765	amino acid transport
FY144_14970	COG0765	amino acid transport
FY144_14975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_14990	COG3938	Belongs to the proline racemase family
FY144_15000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_15010	COG0765	amino acid transport
FY144_15030	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY144_15035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_15045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY144_15050	COG0784	Response regulator, receiver
FY144_15065	COG0842	Transport permease protein
FY144_15070	COG0842	Transport permease protein
FY144_15070	COG1129	ABC transporter
FY144_15075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_15080	COG1486	melibiose metabolic process
FY144_15085	COG4172	Belongs to the ABC transporter superfamily
FY144_15090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_15095	COG0601	transmembrane transport
FY144_15100	COG0747	negative chemotaxis
FY144_15105	COG1486	melibiose metabolic process
FY144_15130	COG1940	carbohydrate kinase activity
FY144_15135	COG2182	Extracellular solute-binding protein
FY144_15140	COG1175	transmembrane transport
FY144_15145	COG0395	ABC-type sugar transport system, permease component
FY144_15150	COG0165	Argininosuccinate lyase
FY144_15155	COG3842	ATPase activity
FY144_15160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_15165	COG3119	arylsulfatase activity
FY144_15175	COG0583	DNA-binding transcription factor activity
FY144_15180	COG1120	ATPase activity
FY144_15185	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_15190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_15200	COG4774	siderophore transport
FY144_15210	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY144_15225	COG2205	protein histidine kinase activity
FY144_15230	COG0745	RESPONSE REGULATOR receiver
FY144_15250	COG1392	Phosphate transport regulator
FY144_15255	COG0306	phosphate transporter
FY144_15260	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY144_15270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY144_15280	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_15285	COG3300	MHYT domain
FY144_15285	COG5001	Diguanylate cyclase
FY144_15305	COG2186	Transcriptional regulator
FY144_15310	COG0601	transmembrane transport
FY144_15315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_15335	COG3842	ATPase activity
FY144_15340	COG0395	ABC-type sugar transport system, permease component
FY144_15355	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_15355	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_15360	COG1609	Transcriptional regulator
FY144_15375	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY144_15380	COG1088	dTDP-glucose 4,6-dehydratase activity
FY144_15385	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY144_15390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY144_15400	COG2801	Transposase and inactivated derivatives
FY144_15410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_15415	COG3754	Rhamnan synthesis protein F
FY144_15430	COG4372	Transposase
FY144_15435	COG3436	PFAM IS66 Orf2 family protein
FY144_15450	COG2226	methyltransferase
FY144_15475	COG4372	Transposase
FY144_15480	COG3436	PFAM IS66 Orf2 family protein
FY144_15495	COG1132	(ABC) transporter
FY144_15525	COG0583	DNA-binding transcription factor activity
FY144_15530	COG0667	Aldo Keto reductase
FY144_15535	COG0385	Bile acid
FY144_15595	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY144_15615	COG3842	ATPase activity
FY144_15640	COG0300	oxidoreductase activity
FY144_15645	COG0584	glycerophosphoryl diester phosphodiesterase
FY144_15650	COG1940	carbohydrate kinase activity
FY144_15660	COG3712	iron ion homeostasis
FY144_15665	COG4774	siderophore transport
FY144_15670	COG2814	Major facilitator Superfamily
FY144_15690	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY144_15705	COG1175	transmembrane transport
FY144_15710	COG0395	ABC-type sugar transport system, permease component
FY144_15715	COG1609	Transcriptional regulator
FY144_15725	COG0673	inositol 2-dehydrogenase activity
FY144_15745	COG1609	Transcriptional regulator
FY144_15750	COG0183	Belongs to the thiolase family
FY144_15755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY144_15765	COG1414	Transcriptional regulator
FY144_15780	COG0583	DNA-binding transcription factor activity
FY144_15790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY144_15795	COG3485	protocatechuate 3,4-dioxygenase
FY144_15800	COG3485	protocatechuate 3,4-dioxygenase
FY144_15805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY144_15810	COG0765	amino acid transport
FY144_15815	COG0765	amino acid transport
FY144_15820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_15830	COG1126	abc transporter atp-binding protein
FY144_15835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY144_15840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY144_15865	COG0747	negative chemotaxis
FY144_15875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_15890	COG0683	leucine binding
FY144_15905	COG0411	ABC transporter
FY144_15920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_15925	COG3962	Belongs to the TPP enzyme family
FY144_15935	COG3718	enzyme involved in inositol metabolism
FY144_15945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_15950	COG1609	Transcriptional regulator
FY144_15955	COG1846	Transcriptional regulator
FY144_15965	COG0523	cobalamin synthesis protein
FY144_15995	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY144_16015	COG0800	Aldolase
FY144_16020	COG2954	triphosphatase activity
FY144_16030	COG1054	Belongs to the UPF0176 family
FY144_16035	COG3300	MHYT domain
FY144_16035	COG5001	Diguanylate cyclase
FY144_16045	COG2011	ABC-type metal ion transport system permease component
FY144_16050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY144_16055	COG0778	Nitroreductase
FY144_16065	COG2115	Belongs to the xylose isomerase family
FY144_16070	COG1070	Carbohydrate kinase
FY144_16075	COG1609	Transcriptional regulator
FY144_16095	COG1309	transcriptional regulator
FY144_16100	COG1253	flavin adenine dinucleotide binding
FY144_16105	COG3273	potassium ion transport
FY144_16105	COG0471	metal ion transport
FY144_16110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY144_16115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY144_16120	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY144_16130	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY144_16135	COG1121	(ABC) transporter
FY144_16140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY144_16145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY144_16155	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_16160	COG1414	Transcriptional regulator
FY144_16165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY144_16180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY144_16205	COG1069	ribulokinase activity
FY144_16230	COG0395	ABC-type sugar transport system, permease component
FY144_16235	COG1175	transmembrane transport
FY144_16245	COG2390	Transcriptional regulator
FY144_16250	COG4172	Belongs to the ABC transporter superfamily
FY144_16255	COG1473	amidohydrolase
FY144_16265	COG0601	transmembrane transport
FY144_16270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_16280	COG0693	protein deglycase activity
FY144_16285	COG0154	amidase activity
FY144_16290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_16300	COG0747	negative chemotaxis
FY144_16305	COG0583	DNA-binding transcription factor activity
FY144_16310	COG4608	Belongs to the ABC transporter superfamily
FY144_16315	COG0444	Belongs to the ABC transporter superfamily
FY144_16320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_16325	COG0601	transmembrane transport
FY144_16330	COG0747	negative chemotaxis
FY144_16345	COG1473	amidohydrolase
FY144_16350	COG2814	Major facilitator Superfamily
FY144_16355	COG0583	DNA-binding transcription factor activity
FY144_16360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY144_16370	COG3842	ATPase activity
FY144_16380	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_16390	COG1609	Transcriptional regulator
FY144_16395	COG0583	DNA-binding transcription factor activity
FY144_16400	COG1960	acyl-CoA dehydrogenase activity
FY144_16405	COG1629	transport
FY144_16405	COG4774	siderophore transport
FY144_16415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_16430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_16440	COG2375	cellular response to nickel ion
FY144_16450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY144_16455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY144_16455	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY144_16465	COG1169	isochorismate synthase
FY144_16470	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY144_16475	COG1535	isochorismatase
FY144_16475	COG3433	isochorismatase activity
FY144_16480	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_16495	COG3005	denitrification pathway
FY144_16505	COG0243	molybdopterin cofactor binding
FY144_16520	COG4459	periplasmic nitrate reductase
FY144_16530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY144_16555	COG0826	peptidase U32
FY144_16565	COG3189	MarR family transcriptional regulator
FY144_16570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY144_16575	COG0163	prenyltransferase activity
FY144_16585	COG1845	cytochrome c oxidase, subunit III
FY144_16600	COG3256	nitric oxide reductase
FY144_16605	COG0714	Associated with various cellular activities
FY144_16665	COG0673	inositol 2-dehydrogenase activity
FY144_16675	COG1609	Transcriptional regulator
FY144_16680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_16685	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_16690	COG1129	ABC transporter
FY144_16695	COG1879	ABC-type sugar transport system periplasmic component
FY144_16700	COG3547	Transposase (IS116 IS110 IS902 family)
FY144_16710	COG0583	DNA-binding transcription factor activity
FY144_16725	COG1609	Transcriptional regulator
FY144_16730	COG0673	inositol 2-dehydrogenase activity
FY144_16740	COG1653	transport
FY144_16745	COG1175	transmembrane transport
FY144_16750	COG0395	ABC-type sugar transport system, permease component
FY144_16755	COG3842	ATPase activity
FY144_16770	COG1253	flavin adenine dinucleotide binding
FY144_16795	COG5001	Diguanylate cyclase
FY144_16795	COG3300	MHYT domain
FY144_16920	COG0477	Major facilitator Superfamily
FY144_16940	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_16950	COG1879	ABC-type sugar transport system periplasmic component
FY144_16960	COG1063	alcohol dehydrogenase
FY144_16975	COG1136	(ABC) transporter
FY144_16990	COG1309	transcriptional regulator
FY144_17010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY144_17020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_17020	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_17035	COG0047	phosphoribosylformylglycinamidine synthase activity
FY144_17050	COG1845	cytochrome c oxidase, subunit III
FY144_17055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_17060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY144_17065	COG3474	cytochrome
FY144_17090	COG3842	ATPase activity
FY144_17095	COG0395	ABC-type sugar transport system, permease component
FY144_17100	COG1175	transmembrane transport
FY144_17105	COG1653	transport
FY144_17110	COG1012	belongs to the aldehyde dehydrogenase family
FY144_17115	COG1024	Enoyl-CoA hydratase
FY144_17135	COG4702	Belongs to the UPF0303 family
FY144_17140	COG1629	transport
FY144_17140	COG4774	siderophore transport
FY144_17145	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY144_17150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_17155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_17160	COG1120	ATPase activity
FY144_17175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY144_17185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY144_17190	COG1177	transmembrane transport
FY144_17195	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_17200	COG3842	ATPase activity
FY144_17225	COG1335	isochorismatase
FY144_17240	COG0583	DNA-binding transcription factor activity
FY144_17245	COG2318	DinB family
FY144_17270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY144_17300	COG0778	Nitroreductase
FY144_17320	COG0277	FAD linked oxidase domain protein
FY144_17340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_17345	COG4172	Belongs to the ABC transporter superfamily
FY144_17355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_17365	COG0431	NADPH-dependent FMN reductase
FY144_17385	COG1522	sequence-specific DNA binding
FY144_17390	COG2376	Dihydroxyacetone kinase
FY144_17420	COG3609	addiction module antidote protein, CC2985 family
FY144_17460	COG1196	nuclear chromosome segregation
FY144_17460	COG0741	lytic transglycosylase activity
FY144_17460	COG0739	heme binding
FY144_17465	COG0542	response to heat
FY144_17475	COG2890	protein-(glutamine-N5) methyltransferase activity
FY144_17480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY144_17490	COG0527	aspartate kinase activity
FY144_17505	COG0019	diaminopimelate decarboxylase activity
FY144_17520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY144_17530	COG3920	Histidine kinase
FY144_17540	COG0784	Response regulator, receiver
FY144_17555	COG1522	sequence-specific DNA binding
FY144_17565	COG1116	anion transmembrane transporter activity
FY144_17570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_17575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_17580	COG1012	belongs to the aldehyde dehydrogenase family
FY144_17585	COG0583	DNA-binding transcription factor activity
FY144_17590	COG0435	Glutathione S-transferase
FY144_17605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY144_17610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_17615	COG0189	ligase activity
FY144_17635	COG0693	protein deglycase activity
FY144_17665	COG3685	Protein conserved in bacteria
FY144_17670	COG4993	Dehydrogenase
FY144_17685	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_17690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY144_17735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_17750	COG0246	Mannitol dehydrogenase
FY144_17755	COG4608	Belongs to the ABC transporter superfamily
FY144_17760	COG0444	Belongs to the ABC transporter superfamily
FY144_17765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_17770	COG0601	transmembrane transport
FY144_17775	COG0747	negative chemotaxis
FY144_17785	COG4221	oxidoreductase activity
FY144_17815	COG0539	negative regulation of cytoplasmic translation
FY144_17820	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY144_17850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY144_17855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY144_17885	COG1294	oxidase, subunit
FY144_17895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY144_17900	COG4988	ABC transporter
FY144_17910	COG1063	alcohol dehydrogenase
FY144_17915	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_17920	COG2084	Dehydrogenase
FY144_17930	COG1522	sequence-specific DNA binding
FY144_17935	COG1794	racemase activity, acting on amino acids and derivatives
FY144_17950	COG0058	SHG alpha-glucan phosphorylase activity
FY144_17955	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY144_17960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY144_17965	COG0297	glycogen (starch) synthase activity
FY144_17970	COG0033	Phosphoglucomutase
FY144_17975	COG1523	belongs to the glycosyl hydrolase 13 family
FY144_17995	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY144_17995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY144_18010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_18015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY144_18035	COG1215	transferase activity, transferring glycosyl groups
FY144_18040	COG2327	Polysaccharide pyruvyl transferase
FY144_18045	COG0463	Glycosyl transferase, family 2
FY144_18050	COG2244	polysaccharide biosynthetic process
FY144_18055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY144_18060	COG2273	Hydrolase Family 16
FY144_18065	COG0438	transferase activity, transferring glycosyl groups
FY144_18070	COG1215	transferase activity, transferring glycosyl groups
FY144_18075	COG1215	transferase activity, transferring glycosyl groups
FY144_18080	COG1215	transferase activity, transferring glycosyl groups
FY144_18085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY144_18090	COG3206	protein involved in exopolysaccharide biosynthesis
FY144_18090	COG0489	protein tyrosine kinase activity
FY144_18095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY144_18115	COG4176	ABC-type proline glycine betaine transport system permease component
FY144_18120	COG3448	diguanylate cyclase activity
FY144_18120	COG4175	Glycine betaine
FY144_18135	COG0564	pseudouridine synthase activity
FY144_18140	COG0500	methyltransferase
FY144_18150	COG2133	pyrroloquinoline quinone binding
FY144_18160	COG2197	response regulator
FY144_18165	COG4585	Histidine kinase
FY144_18170	COG1879	ABC-type sugar transport system periplasmic component
FY144_18175	COG1129	ABC transporter
FY144_18180	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_18190	COG3386	PFAM SMP-30 Gluconolaconase
FY144_18195	COG2137	regulation of response to DNA damage stimulus
FY144_18200	COG3474	cytochrome
FY144_18210	COG1120	ATPase activity
FY144_18225	COG4774	siderophore transport
FY144_18230	COG0583	DNA-binding transcription factor activity
FY144_18240	COG2194	sulfuric ester hydrolase activity
FY144_18255	COG0477	Major facilitator Superfamily
FY144_18280	COG0673	inositol 2-dehydrogenase activity
FY144_18285	COG0697	spore germination
FY144_18295	COG0010	Belongs to the arginase family
FY144_18310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY144_18315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_18320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY144_18325	COG0156	8-amino-7-oxononanoate synthase activity
FY144_18330	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY144_18380	COG0671	phosphoesterase, PA-phosphatase related
FY144_18385	COG0745	RESPONSE REGULATOR receiver
FY144_18400	COG0477	Major facilitator Superfamily
FY144_18405	COG0583	DNA-binding transcription factor activity
FY144_18425	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY144_18440	COG0346	lactoylglutathione lyase activity
FY144_18445	COG0583	DNA-binding transcription factor activity
FY144_18455	COG0840	transmembrane signaling receptor activity
FY144_18470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_18485	COG2828	Protein conserved in bacteria
FY144_18490	COG0583	DNA-binding transcription factor activity
FY144_18495	COG1846	Transcriptional regulator
FY144_18520	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_18525	COG1309	transcriptional regulator
FY144_18530	COG2207	Transcriptional regulator
FY144_18550	COG1566	PFAM secretion protein HlyD family protein
FY144_18565	COG0395	ABC-type sugar transport system, permease component
FY144_18570	COG4166	transmembrane transport
FY144_18575	COG0601	transmembrane transport
FY144_18580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_18585	COG4172	Belongs to the ABC transporter superfamily
FY144_18625	COG0402	S-adenosylhomocysteine deaminase activity
FY144_18630	COG1228	amidohydrolase
FY144_18635	COG2986	histidine ammonia-lyase
FY144_18645	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY144_18675	COG1192	Involved in chromosome partitioning
FY144_18680	COG1475	DNA binding
FY144_18685	COG1414	Transcriptional regulator
FY144_18705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY144_18710	COG4771	TonB-dependent receptor
FY144_18720	COG0366	Alpha amylase catalytic
FY144_18725	COG4770	biotin carboxylase activity
FY144_18730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_18735	COG4336	lyase activity
FY144_18740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_18745	COG1914	H( )-stimulated, divalent metal cation uptake system
FY144_18750	COG1802	Transcriptional regulator
FY144_18755	COG3707	response regulator
FY144_18765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_18770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_18775	COG1116	anion transmembrane transporter activity
FY144_18780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY144_18790	COG0243	molybdopterin cofactor binding
FY144_18795	COG1648	precorrin-2 dehydrogenase activity
FY144_18795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY144_18810	COG3842	ATPase activity
FY144_18825	COG0395	ABC-type sugar transport system, permease component
FY144_18840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY144_18855	COG0071	Belongs to the small heat shock protein (HSP20) family
FY144_18890	COG1879	ABC-type sugar transport system periplasmic component
FY144_18895	COG1129	ABC transporter
FY144_18900	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_18910	COG0667	Aldo Keto reductase
FY144_18915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY144_18920	COG1830	Aldolase
FY144_18925	COG1070	Carbohydrate kinase
FY144_18930	COG0840	transmembrane signaling receptor activity
FY144_18945	COG0436	Aminotransferase
FY144_18955	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY144_18965	COG3842	ATPase activity
FY144_18970	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_18975	COG1984	allophanate hydrolase subunit 2
FY144_18980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY144_18990	COG0439	Biotin carboxylase
FY144_18995	COG0511	ligase activity, forming carbon-carbon bonds
FY144_19000	COG0697	spore germination
FY144_19005	COG0697	spore germination
FY144_19020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_19035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_19040	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_19045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_19050	COG4221	oxidoreductase activity
FY144_19055	COG0765	amino acid transport
FY144_19060	COG0765	amino acid transport
FY144_19070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_19075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_19080	COG1063	alcohol dehydrogenase
FY144_19095	COG1304	FMN binding
FY144_19120	COG3842	ATPase activity
FY144_19130	COG0395	ABC-type sugar transport system, permease component
FY144_19135	COG1175	transmembrane transport
FY144_19150	COG2186	Transcriptional regulator
FY144_19155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY144_19160	COG0488	(ABC) transporter
FY144_19175	COG2307	Protein conserved in bacteria
FY144_19175	COG2308	Evidence 4 Homologs of previously reported genes of
FY144_19215	COG1454	alcohol dehydrogenase
FY144_19220	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY144_19230	COG0747	negative chemotaxis
FY144_19235	COG0601	transmembrane transport
FY144_19240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_19245	COG4172	Belongs to the ABC transporter superfamily
FY144_19250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_19270	COG2986	histidine ammonia-lyase
FY144_19275	COG4175	Glycine betaine
FY144_19275	COG0517	IMP dehydrogenase activity
FY144_19280	COG4176	ABC-type proline glycine betaine transport system permease component
FY144_19300	COG1309	transcriptional regulator
FY144_19320	COG2186	Transcriptional regulator
FY144_19325	COG1027	Aspartate ammonia-lyase
FY144_19335	COG0252	asparaginase activity
FY144_19345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY144_19350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY144_19355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY144_19360	COG2205	protein histidine kinase activity
FY144_19375	COG0067	glutamate synthase
FY144_19375	COG0069	glutamate synthase activity
FY144_19375	COG0070	glutamate synthase
FY144_19390	COG2205	protein histidine kinase activity
FY144_19405	COG2951	lytic endotransglycosylase activity
FY144_19410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY144_19440	COG0330	HflC and HflK could
FY144_19445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY144_19450	COG0737	Belongs to the 5'-nucleotidase family
FY144_19460	COG5310	Homospermidine synthase
FY144_19470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY144_19475	COG1164	Oligoendopeptidase f
FY144_19480	COG2204	response regulator
FY144_19485	COG3108	Peptidase M15
FY144_19490	COG0469	pyruvate kinase activity
FY144_19510	COG3750	Belongs to the UPF0335 family
FY144_19515	COG0457	Tetratricopeptide repeat
FY144_19520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY144_19525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY144_19560	COG0483	inositol monophosphate 1-phosphatase activity
FY144_19580	COG1132	(ABC) transporter
FY144_19585	COG0254	rRNA binding
FY144_19605	COG3588	fructose-bisphosphate aldolase
FY144_19610	COG0126	phosphoglycerate kinase activity
FY144_19650	COG1253	flavin adenine dinucleotide binding
FY144_19660	COG1692	metallophosphoesterase
FY144_19675	COG0217	transcriptional regulatory protein
FY144_19680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_19685	COG0840	transmembrane signaling receptor activity
FY144_19690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY144_19695	COG0632	four-way junction helicase activity
FY144_19700	COG2255	four-way junction helicase activity
FY144_19715	COG0494	nUDIX hydrolase
FY144_19725	COG0824	Thioesterase
FY144_19745	COG0823	Involved in the tonB-independent uptake of proteins
FY144_19750	COG2885	chlorophyll binding
FY144_19760	COG0037	tRNA processing
FY144_19765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY144_19770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY144_19785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY144_19800	COG0482	sulfurtransferase activity
FY144_19835	COG2835	tetraacyldisaccharide 4'-kinase activity
FY144_19840	COG2373	Large extracellular alpha-helical protein
FY144_19845	COG4953	penicillin-binding protein 1C
FY144_19855	COG1473	amidohydrolase
FY144_19860	COG1686	Belongs to the peptidase S11 family
FY144_19865	COG0523	cobalamin synthesis protein
FY144_19870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY144_19870	COG0425	Belongs to the sulfur carrier protein TusA family
FY144_19875	COG3034	peptidoglycan biosynthetic process
FY144_19880	COG0825	malonyl-CoA metabolic process
FY144_19885	COG4974	Belongs to the 'phage' integrase family
FY144_19895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY144_19900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY144_19940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY144_19945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY144_19965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY144_19970	COG2226	methyltransferase
FY144_19975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY144_19980	COG0287	Prephenate dehydrogenase
FY144_19990	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY144_20010	COG2884	Cell division ATP-binding protein ftsE
FY144_20045	COG0165	Argininosuccinate lyase
FY144_20050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY144_20060	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY144_20070	COG2086	electron transfer activity
FY144_20080	COG2096	Adenosyltransferase
FY144_20090	COG0300	oxidoreductase activity
FY144_20100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY144_20110	COG1396	sequence-specific DNA binding
FY144_20110	COG3800	Transcriptional regulator
FY144_20115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY144_20120	COG0625	glutathione transferase activity
FY144_20135	COG4770	biotin carboxylase activity
FY144_20140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY144_20140	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY144_20145	COG0346	lactoylglutathione lyase activity
FY144_20160	COG4213	ABC transporter substrate-binding protein
FY144_20165	COG4214	carbohydrate transport
FY144_20170	COG1129	ABC transporter
FY144_20175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY144_20185	COG1396	sequence-specific DNA binding
FY144_20240	COG3833	ABC-type maltose transport systems, permease component
FY144_20245	COG3842	ATPase activity
FY144_20260	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY144_20260	COG2273	Hydrolase Family 16
FY144_20265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY144_20280	COG0438	transferase activity, transferring glycosyl groups
FY144_20285	COG0438	transferase activity, transferring glycosyl groups
FY144_20305	COG3206	protein involved in exopolysaccharide biosynthesis
FY144_20305	COG0489	protein tyrosine kinase activity
FY144_20315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY144_20330	COG2244	polysaccharide biosynthetic process
FY144_20395	COG0697	spore germination
FY144_20400	COG0653	protein targeting
FY144_20405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY144_20410	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY144_20420	COG0494	nUDIX hydrolase
FY144_20435	COG2226	methyltransferase
FY144_20440	COG1040	competence protein
FY144_20450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY144_20460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_20475	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY144_20480	COG4150	thiosulfate binding
FY144_20490	COG4208	sulfate ABC transporter
FY144_20495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY144_20500	COG4335	DNA alkylation repair
FY144_20515	COG5001	Diguanylate cyclase
FY144_20520	COG2264	protein methyltransferase activity
FY144_20535	COG3254	rhamnose metabolic process
FY144_20540	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_20545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_20550	COG1129	ABC transporter
FY144_20560	COG1349	DNA-binding transcription factor activity
FY144_20565	COG3347	Dehydrogenase
FY144_20565	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_20570	COG4952	isomerase
FY144_20575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY144_20580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY144_20600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY144_20605	COG1960	acyl-CoA dehydrogenase activity
FY144_20615	COG0183	Belongs to the thiolase family
FY144_20620	COG1960	acyl-CoA dehydrogenase activity
FY144_20630	COG0022	dehydrogenase e1 component
FY144_20640	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY144_20645	COG2391	methyltransferase activity
FY144_20655	COG0640	Transcriptional regulator
FY144_20660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY144_20660	COG3453	Protein conserved in bacteria
FY144_20670	COG0300	oxidoreductase activity
FY144_20685	COG2186	Transcriptional regulator
FY144_20695	COG0601	transmembrane transport
FY144_20705	COG0444	Belongs to the ABC transporter superfamily
FY144_20710	COG4608	Belongs to the ABC transporter superfamily
FY144_20730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20755	COG1473	amidohydrolase
FY144_20760	COG0747	negative chemotaxis
FY144_20775	COG4166	transmembrane transport
FY144_20780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20785	COG0583	DNA-binding transcription factor activity
FY144_20795	COG0667	Aldo Keto reductase
FY144_20805	COG0444	Belongs to the ABC transporter superfamily
FY144_20820	COG0747	negative chemotaxis
FY144_20830	COG1960	acyl-CoA dehydrogenase activity
FY144_20860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY144_20875	COG1959	2 iron, 2 sulfur cluster binding
FY144_20880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_20890	COG1473	amidohydrolase
FY144_20900	COG1126	abc transporter atp-binding protein
FY144_20905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_20915	COG0583	DNA-binding transcription factor activity
FY144_20940	COG1522	sequence-specific DNA binding
FY144_20945	COG4172	Belongs to the ABC transporter superfamily
FY144_20950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_20985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_20990	COG1012	belongs to the aldehyde dehydrogenase family
FY144_20995	COG0473	3-isopropylmalate dehydrogenase activity
FY144_21000	COG1012	belongs to the aldehyde dehydrogenase family
FY144_21045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_21050	COG1120	ATPase activity
FY144_21060	COG2226	methyltransferase
FY144_21075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY144_21080	COG1120	ATPase activity
FY144_21085	COG1595	DNA-templated transcription, initiation
FY144_21105	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY144_21110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_21130	COG0673	inositol 2-dehydrogenase activity
FY144_21135	COG0673	inositol 2-dehydrogenase activity
FY144_21145	COG1175	transmembrane transport
FY144_21150	COG0395	ABC-type sugar transport system, permease component
FY144_21155	COG3842	ATPase activity
FY144_21165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_21170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_21175	COG2197	response regulator
FY144_21180	COG0601	transmembrane transport
FY144_21185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_21205	COG0747	negative chemotaxis
FY144_21220	COG1446	asparaginase
FY144_21225	COG0583	DNA-binding transcription factor activity
FY144_21230	COG0601	transmembrane transport
FY144_21235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_21250	COG0747	negative chemotaxis
FY144_21255	COG1473	amidohydrolase
FY144_21270	COG1129	ABC transporter
FY144_21275	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_21280	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY144_21285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY144_21295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY144_21310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_21320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_21325	COG2079	MmgE PrpD family protein
FY144_21330	COG1126	abc transporter atp-binding protein
FY144_21335	COG0765	amino acid transport
FY144_21350	COG0281	malic enzyme
FY144_21350	COG0280	phosphate acetyltransferase
FY144_21355	COG0583	DNA-binding transcription factor activity
FY144_21380	COG1175	transmembrane transport
FY144_21385	COG0395	ABC-type sugar transport system, permease component
FY144_21400	COG0673	inositol 2-dehydrogenase activity
FY144_21405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY144_21410	COG0720	synthase
FY144_21415	COG0602	queuosine metabolic process
FY144_21420	COG0673	inositol 2-dehydrogenase activity
FY144_21430	COG3842	ATPase activity
FY144_21445	COG1653	transport
FY144_21450	COG1609	Transcriptional regulator
FY144_21465	COG2094	Belongs to the DNA glycosylase MPG family
FY144_21475	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_21485	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_21490	COG0840	transmembrane signaling receptor activity
FY144_21495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_21505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY144_21510	COG1596	polysaccharide export
FY144_21515	COG3307	-O-antigen
FY144_21545	COG2197	response regulator
FY144_21555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_21580	COG2942	2-epimerase
FY144_21590	COG1215	transferase activity, transferring glycosyl groups
FY144_21610	COG1473	amidohydrolase
FY144_21620	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_21625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_21630	COG1301	dicarboxylic acid transport
FY144_21635	COG4191	Histidine kinase
FY144_21640	COG2204	response regulator
FY144_21655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_21660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY144_21665	COG1522	sequence-specific DNA binding
FY144_21670	COG0351	phosphomethylpyrimidine kinase
FY144_21675	COG0352	thiamine-phosphate diphosphorylase activity
FY144_21680	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY144_21685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_21690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_21700	COG1501	Belongs to the glycosyl hydrolase 31 family
FY144_21705	COG0395	ABC-type sugar transport system, permease component
FY144_21710	COG1175	transmembrane transport
FY144_21715	COG1653	transport
FY144_21720	COG3842	ATPase activity
FY144_21735	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FY144_21745	COG2188	Transcriptional regulator
FY144_21755	COG4989	oxidoreductase activity
FY144_21795	COG0438	transferase activity, transferring glycosyl groups
FY144_21800	COG0747	negative chemotaxis
FY144_21805	COG0601	transmembrane transport
FY144_21815	COG3964	amidohydrolase
FY144_21830	COG1921	L-seryl-tRNASec selenium transferase activity
FY144_21835	COG4172	Belongs to the ABC transporter superfamily
FY144_21840	COG0625	glutathione transferase activity
FY144_21855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_21860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_21860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY144_21865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_21885	COG1312	Catalyzes the dehydration of D-mannonate
FY144_21890	COG1063	alcohol dehydrogenase
FY144_21895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_21905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_21910	COG2186	Transcriptional regulator
FY144_21915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY144_21920	COG0850	regulation of cytokinetic process
FY144_21925	COG2894	cell division
FY144_21930	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY144_21945	COG5001	Diguanylate cyclase
FY144_21960	COG0673	inositol 2-dehydrogenase activity
FY144_21970	COG1653	transport
FY144_21975	COG1175	transmembrane transport
FY144_21980	COG0395	ABC-type sugar transport system, permease component
FY144_21985	COG3842	ATPase activity
FY144_21995	COG0673	inositol 2-dehydrogenase activity
FY144_22025	COG0587	DNA-directed DNA polymerase activity
FY144_22030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY144_22045	COG2186	Transcriptional regulator
FY144_22050	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_22055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_22060	COG1129	ABC transporter
FY144_22065	COG1879	ABC-type sugar transport system periplasmic component
FY144_22070	COG0129	dihydroxy-acid dehydratase activity
FY144_22080	COG0346	lactoylglutathione lyase activity
FY144_22095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY144_22100	COG4608	Belongs to the ABC transporter superfamily
FY144_22110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_22115	COG0601	transmembrane transport
FY144_22120	COG0747	negative chemotaxis
FY144_22130	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY144_22135	COG5001	Diguanylate cyclase
FY144_22145	COG3257	ureidoglycine aminohydrolase activity
FY144_22155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_22160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY144_22170	COG1129	ABC transporter
FY144_22175	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_22180	COG1879	ABC-type sugar transport system periplasmic component
FY144_22185	COG0583	DNA-binding transcription factor activity
FY144_22210	COG3047	cAMP biosynthetic process
FY144_22220	COG3842	ATPase activity
FY144_22225	COG0395	ABC-type sugar transport system, permease component
FY144_22230	COG1175	transmembrane transport
FY144_22235	COG1653	transport
FY144_22240	COG0523	cobalamin synthesis protein
FY144_22255	COG0523	cobalamin synthesis protein
FY144_22260	COG1121	(ABC) transporter
FY144_22270	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY144_22285	COG0626	cystathionine gamma-synthase activity
FY144_22290	COG2182	Extracellular solute-binding protein
FY144_22295	COG1175	transmembrane transport
FY144_22300	COG0395	ABC-type sugar transport system, permease component
FY144_22315	COG0395	ABC-type sugar transport system, permease component
FY144_22320	COG1175	transmembrane transport
FY144_22325	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY144_22330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY144_22340	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_22345	COG1063	alcohol dehydrogenase
FY144_22350	COG1609	Transcriptional regulator
FY144_22365	COG2084	Dehydrogenase
FY144_22370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_22380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_22385	COG0583	DNA-binding transcription factor activity
FY144_22390	COG2223	nitrite transmembrane transporter activity
FY144_22395	COG4977	sequence-specific DNA binding
FY144_22425	COG0667	Aldo Keto reductase
FY144_22440	COG2186	Transcriptional regulator
FY144_22445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY144_22450	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY144_22455	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_22460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_22465	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_22470	COG3618	amidohydrolase
FY144_22475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_22495	COG1175	transmembrane transport
FY144_22500	COG0395	ABC-type sugar transport system, permease component
FY144_22505	COG3842	ATPase activity
FY144_22520	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY144_22525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY144_22545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY144_22555	COG1278	Cold shock
FY144_22560	COG0673	inositol 2-dehydrogenase activity
FY144_22575	COG0673	inositol 2-dehydrogenase activity
FY144_22580	COG1309	transcriptional regulator
FY144_22585	COG1653	transport
FY144_22590	COG1175	transmembrane transport
FY144_22595	COG0395	ABC-type sugar transport system, permease component
FY144_22600	COG3842	ATPase activity
FY144_22615	COG1082	Xylose isomerase domain protein TIM barrel
FY144_22630	COG1609	Transcriptional regulator
FY144_22660	COG1175	transmembrane transport
FY144_22665	COG0395	ABC-type sugar transport system, permease component
FY144_22670	COG1116	anion transmembrane transporter activity
FY144_22675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_22680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_22690	COG3842	ATPase activity
FY144_22695	COG0395	ABC-type sugar transport system, permease component
FY144_22705	COG1653	transport
FY144_22745	COG3842	ATPase activity
FY144_22755	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY144_22760	COG0395	ABC-type sugar transport system, permease component
FY144_22815	COG2233	PERMEase
FY144_22825	COG0702	epimerase
FY144_22835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY144_22840	COG1522	sequence-specific DNA binding
FY144_22860	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_22875	COG1414	Transcriptional regulator
FY144_22885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY144_22915	COG4566	intracellular signal transduction
FY144_22920	COG4566	intracellular signal transduction
FY144_22930	COG0243	molybdopterin cofactor binding
FY144_22935	COG0783	Belongs to the Dps family
FY144_22950	COG0596	Alpha beta hydrolase
FY144_22960	COG1764	response to oxidative stress
FY144_22975	COG0596	Alpha beta hydrolase
FY144_23010	COG4172	Belongs to the ABC transporter superfamily
FY144_23030	COG0747	negative chemotaxis
FY144_23040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_23045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY144_23060	COG4106	trans-aconitate 2-methyltransferase activity
FY144_23065	COG0025	NhaP-type Na H and K H
FY144_23070	COG4302	ethanolamine ammonia-lyase activity
FY144_23095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY144_23100	COG1349	DNA-binding transcription factor activity
FY144_23105	COG4608	Belongs to the ABC transporter superfamily
FY144_23115	COG0601	transmembrane transport
FY144_23120	COG0747	negative chemotaxis
FY144_23125	COG1454	alcohol dehydrogenase
FY144_23130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY144_23135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY144_23190	COG0668	transmembrane transport
FY144_23205	COG1566	PFAM secretion protein HlyD family protein
FY144_23225	COG1309	transcriptional regulator
FY144_23250	COG3422	double-strand break repair
FY144_23295	COG4372	Transposase
FY144_23315	COG3727	T/G mismatch-specific endonuclease activity
FY144_23445	COG1192	Involved in chromosome partitioning
FY144_23450	COG1475	DNA binding
FY144_23455	COG0640	Transcriptional regulator
FY144_23465	COG0583	DNA-binding transcription factor activity
FY144_23470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY144_23515	COG1126	abc transporter atp-binding protein
FY144_23520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_23525	COG1609	Transcriptional regulator
FY144_23580	COG0210	DNA helicase
FY144_23640	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY144_23640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY144_23710	COG1216	Glycosyl transferase, family 2
FY144_23730	COG3916	Acyl-homoserine-lactone synthase
FY144_23740	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FY144_23745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_23765	COG0840	transmembrane signaling receptor activity
FY144_23780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY144_23805	COG3842	ATPase activity
FY144_23815	COG2390	Transcriptional regulator
FY144_23840	COG3177	Filamentation induced by cAMP protein fic
FY144_23905	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_23915	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_23925	COG1733	regulation of RNA biosynthetic process
FY144_23930	COG1733	regulation of RNA biosynthetic process
FY144_23980	COG3620	sequence-specific DNA binding
FY144_23985	COG3550	peptidyl-serine autophosphorylation
FY144_24030	COG0459	protein refolding
FY144_24035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY144_24065	COG3158	transport of potassium into the cell
FY144_24070	COG0583	DNA-binding transcription factor activity
FY144_24075	COG0667	Aldo Keto reductase
FY144_24090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_24095	COG0601	transmembrane transport
FY144_24105	COG1802	Transcriptional regulator
FY144_24115	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_24120	COG4691	Plasmid stability protein
FY144_24125	COG1487	ribonuclease activity
FY144_24130	COG2186	Transcriptional regulator
FY144_24140	COG1126	abc transporter atp-binding protein
FY144_24150	COG0765	amino acid transport
FY144_24155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY144_24170	COG0436	Aminotransferase
FY144_24175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_24220	COG2207	Transcriptional regulator
FY144_24240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY144_24245	COG1012	belongs to the aldehyde dehydrogenase family
FY144_24250	COG1522	sequence-specific DNA binding
FY144_24255	COG0747	negative chemotaxis
FY144_24260	COG0601	transmembrane transport
FY144_24265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_24270	COG4172	Belongs to the ABC transporter superfamily
FY144_24285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY144_24320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY144_24320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY144_24335	COG0642	Histidine kinase
FY144_24340	COG1376	ErfK ybiS ycfS ynhG family protein
FY144_24355	COG1309	transcriptional regulator
FY144_24370	COG2020	methyltransferase activity
FY144_24385	COG5489	Protein of unknown function (DUF736)
FY144_24395	COG4974	Belongs to the 'phage' integrase family
FY144_24400	COG0582	viral genome integration into host DNA
FY144_24405	COG4974	Belongs to the 'phage' integrase family
FY144_24410	COG5489	Protein of unknown function (DUF736)
FY144_24435	COG3838	Conjugal transfer protein Trbc
FY144_24440	COG3702	type iv secretory pathway
FY144_24445	COG3451	type IV secretory pathway VirB4
FY144_24460	COG3704	protein secretion by the type IV secretion system
FY144_24470	COG3736	Type IV secretory pathway, component VirB8
FY144_24475	COG3504	Conjugal transfer protein
FY144_24480	COG2948	multi-organism process
FY144_24485	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY144_24495	COG0776	regulation of translation
FY144_24505	COG3505	Type IV secretory pathway VirD4
FY144_24545	COG0583	DNA-binding transcription factor activity
FY144_24555	COG1609	Transcriptional regulator
FY144_24595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY144_24600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY144_24600	COG2010	Cytochrome c
FY144_24615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY144_24645	COG3734	2-keto-3-deoxy-galactonokinase
FY144_24650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY144_24655	COG4948	Mandelate Racemase Muconate Lactonizing
FY144_24665	COG1175	transmembrane transport
FY144_24670	COG0395	ABC-type sugar transport system, permease component
FY144_24675	COG3842	ATPase activity
FY144_24680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY144_24685	COG1414	Transcriptional regulator
FY144_24690	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_24695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY144_24705	COG3920	Histidine kinase
FY144_24730	COG2354	Protein conserved in bacteria
FY144_24735	COG0598	Magnesium transport protein CorA
FY144_24765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY144_24770	COG2826	transposase and inactivated derivatives, IS30 family
FY144_24780	COG3177	Filamentation induced by cAMP protein fic
FY144_24795	COG0071	Belongs to the small heat shock protein (HSP20) family
FY144_24810	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY144_24815	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY144_24835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY144_24845	COG1247	-acetyltransferase
FY144_24850	COG1396	sequence-specific DNA binding
FY144_24870	COG0583	DNA-binding transcription factor activity
FY144_24925	COG1573	uracil-dna glycosylase
FY144_24980	COG3685	Protein conserved in bacteria
FY144_24985	COG0753	catalase activity
FY144_25025	COG0798	PFAM Bile acid sodium symporter
FY144_25040	COG0640	Transcriptional regulator
FY144_25055	COG1942	4-Oxalocrotonate Tautomerase
FY144_25065	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY144_25085	COG4585	Histidine kinase
FY144_25090	COG2197	response regulator
FY144_25110	COG0583	DNA-binding transcription factor activity
FY144_25115	COG1741	Belongs to the pirin family
FY144_25130	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25140	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25150	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25155	COG4221	oxidoreductase activity
FY144_25175	COG4221	oxidoreductase activity
FY144_25285	COG1929	Belongs to the glycerate kinase type-1 family
FY144_25300	COG0300	oxidoreductase activity
FY144_25310	COG0583	DNA-binding transcription factor activity
FY144_25325	COG2207	Transcriptional regulator
FY144_25330	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25340	COG1335	isochorismatase
FY144_25350	COG0667	Aldo Keto reductase
FY144_25355	COG2267	carboxylic ester hydrolase activity
FY144_25365	COG0604	alcohol dehydrogenase
FY144_25370	COG1902	pentaerythritol trinitrate reductase activity
FY144_25375	COG0300	oxidoreductase activity
FY144_25380	COG1309	transcriptional regulator
FY144_25385	COG2207	Transcriptional regulator
FY144_25410	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY144_25420	COG1846	Transcriptional regulator
FY144_25425	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25435	COG0583	DNA-binding transcription factor activity
FY144_25495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY144_25505	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25515	COG0395	ABC-type sugar transport system, permease component
FY144_25540	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25545	COG1349	DNA-binding transcription factor activity
FY144_25550	COG1069	ribulokinase activity
FY144_25570	COG1846	Transcriptional regulator
FY144_25570	COG1940	carbohydrate kinase activity
FY144_25630	COG1278	Cold shock
FY144_25640	COG1803	Methylglyoxal synthase
FY144_25640	COG1597	lipid kinase activity
FY144_25645	COG1522	sequence-specific DNA binding
FY144_25660	COG2814	Major facilitator Superfamily
FY144_25675	COG1846	Transcriptional regulator
FY144_25680	COG2807	transmembrane transport
FY144_25685	COG2211	Major facilitator Superfamily
FY144_25710	COG2814	Major facilitator Superfamily
FY144_25715	COG1846	Transcriptional regulator
FY144_25770	COG5002	protein histidine kinase activity
FY144_25820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY144_25825	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_25830	COG1129	ABC transporter
FY144_25840	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_25845	COG3959	Transketolase, thiamine diphosphate binding domain
FY144_25850	COG3958	Transketolase
FY144_25855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY144_25860	COG2390	Transcriptional regulator
FY144_25870	COG4977	sequence-specific DNA binding
FY144_25880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FY144_25920	COG5001	Diguanylate cyclase
FY144_25920	COG3300	MHYT domain
FY144_25955	COG2084	Dehydrogenase
FY144_25960	COG3622	Belongs to the hyi family
FY144_25970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_25975	COG0601	transmembrane transport
FY144_25985	COG0747	negative chemotaxis
FY144_25990	COG1609	Transcriptional regulator
FY144_25995	COG3239	Fatty acid desaturase
FY144_26025	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FY144_26030	COG3920	Histidine kinase
FY144_26030	COG2202	Pas domain
FY144_26045	COG0577	efflux transmembrane transporter activity
FY144_26045	COG1136	(ABC) transporter
FY144_26050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY144_26060	COG0745	RESPONSE REGULATOR receiver
FY144_26115	COG0583	DNA-binding transcription factor activity
FY144_26135	COG0583	DNA-binding transcription factor activity
FY144_26150	COG1192	Involved in chromosome partitioning
FY144_26155	COG1475	DNA binding
FY144_26160	COG0640	Transcriptional regulator
FY144_26165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY144_26210	COG0583	DNA-binding transcription factor activity
FY144_26220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_26225	COG1116	anion transmembrane transporter activity
FY144_26230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_26240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_26245	COG1028	Short-chain dehydrogenase reductase Sdr
FY144_26275	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY144_26280	COG1129	ABC transporter
FY144_26305	COG4172	Belongs to the ABC transporter superfamily
FY144_26310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_26315	COG0601	transmembrane transport
FY144_26325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_26330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_26335	COG0583	DNA-binding transcription factor activity
FY144_26345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY144_26355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY144_26360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY144_26365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY144_26440	COG1475	DNA binding
FY144_26460	COG2824	Alkylphosphonate utilization operon protein PhnA
FY144_26480	COG5489	Protein of unknown function (DUF736)
FY144_26505	COG0494	nUDIX hydrolase
FY144_26515	COG5489	Protein of unknown function (DUF736)
FY144_26600	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY144_26615	COG0747	negative chemotaxis
FY144_26635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY144_26640	COG0584	glycerophosphoryl diester phosphodiesterase
FY144_26645	COG0483	inositol monophosphate 1-phosphatase activity
FY144_26705	COG3161	chorismate lyase activity
FY144_26855	COG3436	PFAM IS66 Orf2 family protein
FY144_26990	COG0145	ligase activity
FY144_27000	COG0583	DNA-binding transcription factor activity
FY144_27050	COG3701	Conjugal transfer protein
FY144_27055	COG3846	protein secretion by the type IV secretion system
FY144_27065	COG5314	conjugation
FY144_27070	COG3451	type IV secretory pathway VirB4
FY144_27085	COG4962	Type ii secretion system protein e