locus-tag	class	description
FY145_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY145_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY145_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY145_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY145_00025	COG1420	regulation of RNA biosynthetic process
FY145_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY145_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY145_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY145_00050	COG1137	ATPase activity
FY145_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY145_00065	COG0616	signal peptide processing
FY145_00070	COG0776	regulation of translation
FY145_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY145_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY145_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY145_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY145_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY145_00115	COG0728	peptidoglycan biosynthetic process
FY145_00125	COG0180	Tryptophanyl-tRNA synthetase
FY145_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY145_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY145_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY145_00165	COG1702	phosphate starvation-inducible protein PhoH
FY145_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY145_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY145_00185	COG1396	sequence-specific DNA binding
FY145_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY145_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY145_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_00210	COG0242	peptide deformylase activity
FY145_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY145_00220	COG0101	tRNA pseudouridine synthase activity
FY145_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY145_00235	COG2171	N-acyltransferase activity
FY145_00245	COG0840	transmembrane signaling receptor activity
FY145_00250	COG1957	nucleoside hydrolase
FY145_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY145_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY145_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY145_00295	COG0706	membrane insertase activity
FY145_00300	COG0594	ribonuclease P activity
FY145_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY145_00310	COG0840	transmembrane signaling receptor activity
FY145_00325	COG2226	methyltransferase
FY145_00330	COG3842	ATPase activity
FY145_00335	COG1175	transmembrane transport
FY145_00340	COG0395	ABC-type sugar transport system, permease component
FY145_00355	COG0427	acetyl-CoA hydrolase
FY145_00365	COG3938	Belongs to the proline racemase family
FY145_00370	COG0418	dihydroorotase activity
FY145_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY145_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY145_00400	COG0166	Belongs to the GPI family
FY145_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY145_00410	COG3842	ATPase activity
FY145_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY145_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY145_00425	COG4774	siderophore transport
FY145_00470	COG2326	polyphosphate kinase activity
FY145_00475	COG5002	protein histidine kinase activity
FY145_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY145_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY145_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY145_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY145_00505	COG0745	RESPONSE REGULATOR receiver
FY145_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY145_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY145_00530	COG2967	ApaG domain
FY145_00545	COG0717	Belongs to the dCTP deaminase family
FY145_00555	COG0582	viral genome integration into host DNA
FY145_00580	COG0419	ATPase involved in DNA repair
FY145_00600	COG1396	sequence-specific DNA binding
FY145_00640	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY145_00645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY145_00695	COG0167	dihydroorotate dehydrogenase activity
FY145_00730	COG1959	2 iron, 2 sulfur cluster binding
FY145_00735	COG1201	RNA secondary structure unwinding
FY145_00765	COG1960	acyl-CoA dehydrogenase activity
FY145_00770	COG0183	Belongs to the thiolase family
FY145_00780	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY145_00780	COG1024	Enoyl-CoA hydratase
FY145_00805	COG1320	monovalent cation:proton antiporter activity
FY145_00810	COG2212	antiporter activity
FY145_00815	COG1863	multisubunit Na H antiporter MnhE subunit
FY145_00820	COG0651	ATP synthesis coupled electron transport
FY145_00825	COG1006	Multisubunit Na H antiporter MnhC subunit
FY145_00830	COG2111	Na H antiporter
FY145_00830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY145_00840	COG0840	transmembrane signaling receptor activity
FY145_00850	COG0745	RESPONSE REGULATOR receiver
FY145_00855	COG0643	Histidine kinase
FY145_00855	COG2198	Histidine kinase
FY145_00860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY145_00865	COG2201	protein-glutamate methylesterase activity
FY145_00870	COG0745	RESPONSE REGULATOR receiver
FY145_00875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY145_00885	COG1766	The M ring may be actively involved in energy transduction
FY145_00890	COG2771	luxR family
FY145_00900	COG0840	transmembrane signaling receptor activity
FY145_00900	COG2972	Histidine kinase
FY145_00905	COG0784	Response regulator, receiver
FY145_00905	COG2198	Histidine kinase
FY145_00905	COG2205	protein histidine kinase activity
FY145_00910	COG1970	mechanosensitive ion channel activity
FY145_00915	COG0436	Aminotransferase
FY145_00930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY145_00935	COG0424	maF-like protein
FY145_00940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY145_00950	COG5328	Belongs to the UPF0262 family
FY145_00955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY145_00965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY145_01100	COG5484	DNA packaging
FY145_01100	COG3728	DNA packaging
FY145_01150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY145_01235	COG0582	viral genome integration into host DNA
FY145_01245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY145_01255	COG1338	Plays a role in the flagellum-specific transport system
FY145_01265	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY145_01275	COG1706	bacterial-type flagellum-dependent cell motility
FY145_01280	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY145_01285	COG4786	Flagellar basal body rod
FY145_01290	COG1677	Flagellar hook-basal body complex protein FliE
FY145_01295	COG1558	bacterial-type flagellum-dependent cell motility
FY145_01300	COG1815	bacterial-type flagellum-dependent cell motility
FY145_01310	COG1157	protein secretion by the type III secretion system
FY145_01315	COG4786	Flagellar basal body rod
FY145_01325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY145_01330	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY145_01335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY145_01340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY145_01345	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY145_01365	COG1360	Flagellar Motor Protein
FY145_01410	COG5443	negative regulation of bacterial-type flagellum assembly
FY145_01415	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY145_01425	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY145_01465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY145_01470	COG1609	Transcriptional regulator
FY145_01475	COG1653	transport
FY145_01480	COG1175	transmembrane transport
FY145_01485	COG0395	ABC-type sugar transport system, permease component
FY145_01490	COG0366	Alpha amylase catalytic
FY145_01495	COG3842	ATPase activity
FY145_01510	COG0129	dihydroxy-acid dehydratase activity
FY145_01515	COG0363	glucosamine-6-phosphate deaminase activity
FY145_01520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY145_01525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_01535	COG2081	HI0933 family
FY145_01555	COG2224	Isocitrate lyase
FY145_01570	COG3842	ATPase activity
FY145_01575	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_01580	COG1177	transmembrane transport
FY145_01595	COG2205	protein histidine kinase activity
FY145_01605	COG0248	Ppx GppA phosphatase
FY145_01610	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY145_01615	COG0477	Major facilitator Superfamily
FY145_01645	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY145_01650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY145_01660	COG0142	geranyltranstransferase activity
FY145_01685	COG0752	glycyl-tRNA synthetase alpha subunit
FY145_01695	COG1704	LemA family
FY145_01700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY145_01710	COG0751	glycine-tRNA ligase activity
FY145_01715	COG1683	Conserved Protein
FY145_01720	COG0840	transmembrane signaling receptor activity
FY145_01730	COG0151	Belongs to the GarS family
FY145_01735	COG2183	response to ionizing radiation
FY145_01740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY145_01765	COG0583	DNA-binding transcription factor activity
FY145_01785	COG0306	phosphate transporter
FY145_01795	COG0561	phosphatase activity
FY145_01800	COG0438	transferase activity, transferring glycosyl groups
FY145_01805	COG2186	Transcriptional regulator
FY145_01815	COG0583	DNA-binding transcription factor activity
FY145_01820	COG0277	FAD linked oxidase domain protein
FY145_01825	COG0277	FAD linked oxidase domain protein
FY145_01830	COG0247	lactate metabolic process
FY145_01840	COG1376	ErfK ybiS ycfS ynhG family protein
FY145_01845	COG2818	Glycosylase
FY145_01855	COG2855	membrane
FY145_01860	COG0583	DNA-binding transcription factor activity
FY145_01890	COG0124	histidyl-tRNA synthetase
FY145_01900	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY145_01905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY145_01910	COG2259	Doxx family
FY145_01920	COG0459	protein refolding
FY145_01925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY145_01935	COG0196	riboflavin kinase activity
FY145_01940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY145_01950	COG0590	tRNA wobble adenosine to inosine editing
FY145_01955	COG1187	pseudouridine synthase activity
FY145_01960	COG0742	ribosomal rna small subunit methyltransferase
FY145_01965	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY145_01975	COG0312	modulator of DNA gyrase
FY145_01980	COG0483	inositol monophosphate 1-phosphatase activity
FY145_01990	COG1519	Transferase
FY145_02000	COG1663	tetraacyldisaccharide 4'-kinase activity
FY145_02010	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY145_02015	COG0745	RESPONSE REGULATOR receiver
FY145_02020	COG5001	Diguanylate cyclase
FY145_02020	COG3300	MHYT domain
FY145_02025	COG3386	PFAM SMP-30 Gluconolaconase
FY145_02030	COG0800	Aldolase
FY145_02035	COG3734	2-keto-3-deoxy-galactonokinase
FY145_02040	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_02045	COG1414	Transcriptional regulator
FY145_02050	COG2197	response regulator
FY145_02065	COG0598	Magnesium transport protein CorA
FY145_02070	COG3158	transport of potassium into the cell
FY145_02085	COG0356	it plays a direct role in the translocation of protons across the membrane
FY145_02095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY145_02100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY145_02115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY145_02135	COG0009	L-threonylcarbamoyladenylate synthase
FY145_02145	COG4638	Rieske (2fe-2S)
FY145_02170	COG1960	acyl-CoA dehydrogenase activity
FY145_02185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY145_02190	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY145_02195	COG0840	transmembrane signaling receptor activity
FY145_02205	COG1522	sequence-specific DNA binding
FY145_02230	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY145_02235	COG1741	Belongs to the pirin family
FY145_02240	COG1722	exodeoxyribonuclease VII activity
FY145_02245	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY145_02250	COG1268	BioY protein
FY145_02255	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY145_02260	COG1122	ATPase activity
FY145_02265	COG3214	Protein conserved in bacteria
FY145_02270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY145_02270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY145_02275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY145_02295	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY145_02310	COG0259	pyridoxamine-phosphate oxidase activity
FY145_02340	COG0312	modulator of DNA gyrase
FY145_02355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY145_02360	COG0109	protoheme IX farnesyltransferase activity
FY145_02365	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY145_02380	COG3346	SURF1 family
FY145_02385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY145_02390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY145_02395	COG0328	RNA-DNA hybrid ribonuclease activity
FY145_02405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY145_02405	COG0678	peroxiredoxin activity
FY145_02415	COG1678	Uncharacterized ACR, COG1678
FY145_02420	COG3237	CsbD-like
FY145_02430	COG3300	MHYT domain
FY145_02430	COG5001	Diguanylate cyclase
FY145_02435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY145_02440	COG0612	Peptidase, M16
FY145_02465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY145_02470	COG1802	Transcriptional regulator
FY145_02485	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY145_02490	COG3609	addiction module antidote protein, CC2985 family
FY145_02495	COG3668	Plasmid stabilization system
FY145_02505	COG1194	a g-specific adenine glycosylase
FY145_02520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY145_02525	COG1196	nuclear chromosome segregation
FY145_02530	COG2514	catechol 2,3-dioxygenase activity
FY145_02535	COG0574	Belongs to the PEP-utilizing enzyme family
FY145_02535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY145_02545	COG1823	symporter activity
FY145_02570	COG0579	oxidoreductase
FY145_02585	COG2895	sulfate adenylyltransferase (ATP) activity
FY145_02590	COG0175	sulfate reduction
FY145_02595	COG0175	sulfate reduction
FY145_02600	COG1959	2 iron, 2 sulfur cluster binding
FY145_02605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY145_02610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY145_02615	COG4208	sulfate ABC transporter
FY145_02620	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY145_02630	COG2199	diguanylate cyclase activity
FY145_02630	COG2200	EAL domain
FY145_02630	COG2203	Gaf domain
FY145_02640	COG1309	transcriptional regulator
FY145_02645	COG1012	belongs to the aldehyde dehydrogenase family
FY145_02650	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY145_02680	COG0625	glutathione transferase activity
FY145_02690	COG0477	Major facilitator Superfamily
FY145_02700	COG3657	addiction module killer protein
FY145_02710	COG1793	dna ligase
FY145_02730	COG1376	ErfK ybiS ycfS ynhG family protein
FY145_02735	COG1376	ErfK ybiS ycfS ynhG family protein
FY145_02740	COG1846	Transcriptional regulator
FY145_02745	COG1764	response to oxidative stress
FY145_02760	COG0488	(ABC) transporter
FY145_02795	COG4221	oxidoreductase activity
FY145_02810	COG0433	COG0433 Predicted ATPase
FY145_02820	COG1733	regulation of RNA biosynthetic process
FY145_02825	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY145_02840	COG0656	L-ascorbic acid biosynthetic process
FY145_02845	COG3781	membrane
FY145_02850	COG2378	regulation of single-species biofilm formation
FY145_02860	COG4106	trans-aconitate 2-methyltransferase activity
FY145_02865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY145_02870	COG0840	transmembrane signaling receptor activity
FY145_02875	COG0583	DNA-binding transcription factor activity
FY145_02890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY145_02910	COG3909	cytochrome
FY145_02915	COG2010	Cytochrome c
FY145_02950	COG0789	Transcriptional regulator
FY145_02975	COG0517	IMP dehydrogenase activity
FY145_02975	COG4175	Glycine betaine
FY145_02980	COG4176	ABC-type proline glycine betaine transport system permease component
FY145_03000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_03010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY145_03010	COG2169	Transcriptional regulator
FY145_03020	COG2514	catechol 2,3-dioxygenase activity
FY145_03040	COG1272	protein, Hemolysin III
FY145_03050	COG1280	lysine exporter protein (LysE YggA)
FY145_03055	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY145_03060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY145_03060	COG2111	Na H antiporter
FY145_03065	COG2111	Na H antiporter
FY145_03070	COG1006	Multisubunit Na H antiporter MnhC subunit
FY145_03075	COG0651	ATP synthesis coupled electron transport
FY145_03080	COG1863	multisubunit Na H antiporter MnhE subunit
FY145_03085	COG2212	antiporter activity
FY145_03090	COG1320	monovalent cation:proton antiporter activity
FY145_03095	COG4957	zinc ion binding
FY145_03110	COG2166	iron-sulfur cluster assembly
FY145_03120	COG2205	protein histidine kinase activity
FY145_03165	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY145_03170	COG2983	Belongs to the UPF0260 family
FY145_03185	COG2217	Heavy metal translocating P-type atpase
FY145_03215	COG2814	Major facilitator Superfamily
FY145_03220	COG1621	beta-fructofuranosidase activity
FY145_03225	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY145_03275	COG4695	Portal protein
FY145_03380	COG4235	cytochrome complex assembly
FY145_03385	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY145_03390	COG1138	Cytochrome C-type biogenesis protein
FY145_03395	COG3088	subunit of a heme lyase
FY145_03400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY145_03405	COG0745	RESPONSE REGULATOR receiver
FY145_03410	COG2205	protein histidine kinase activity
FY145_03415	COG3011	Protein conserved in bacteria
FY145_03420	COG3713	MltA-interacting MipA family protein
FY145_03425	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY145_03430	COG2202	Pas domain
FY145_03430	COG2205	protein histidine kinase activity
FY145_03440	COG0308	aminopeptidase N
FY145_03445	COG0697	spore germination
FY145_03460	COG0443	Heat shock 70 kDa protein
FY145_03495	COG0604	alcohol dehydrogenase
FY145_03500	COG1733	regulation of RNA biosynthetic process
FY145_03505	COG1968	undecaprenyl-diphosphatase activity
FY145_03510	COG2239	Acts as a magnesium transporter
FY145_03515	COG2814	Major facilitator Superfamily
FY145_03540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY145_03565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY145_03605	COG0741	lytic transglycosylase activity
FY145_03610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_03615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY145_03620	COG0840	transmembrane signaling receptor activity
FY145_03630	COG1758	RNA polymerase activity
FY145_03650	COG0736	holo-[acyl-carrier-protein] synthase activity
FY145_03655	COG0681	Belongs to the peptidase S26 family
FY145_03660	COG0571	ribonuclease III activity
FY145_03665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY145_03675	COG0784	Response regulator, receiver
FY145_03680	COG1381	Involved in DNA repair and RecF pathway recombination
FY145_03690	COG2226	methyltransferase
FY145_03700	COG1418	mRNA catabolic process
FY145_03710	COG0346	lactoylglutathione lyase activity
FY145_03725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_03730	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY145_03735	COG0668	transmembrane transport
FY145_03745	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY145_03775	COG1742	UPF0060 membrane protein
FY145_03790	COG1183	phosphatidylcholine synthase activity
FY145_03795	COG0688	phosphatidylethanolamine metabolic process
FY145_03800	COG5265	(ABC) transporter
FY145_03840	COG2852	Protein conserved in bacteria
FY145_03845	COG0215	cysteine-tRNA ligase activity
FY145_03850	COG4221	oxidoreductase activity
FY145_03855	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY145_03860	COG1286	toxin biosynthetic process
FY145_03875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY145_03885	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY145_03895	COG0305	Participates in initiation and elongation during chromosome replication
FY145_03915	COG0359	binds to the 23S rRNA
FY145_03925	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY145_03930	COG0360	Binds together with S18 to 16S ribosomal RNA
FY145_03940	COG0667	Aldo Keto reductase
FY145_03945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY145_03955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY145_03960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY145_03970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY145_03975	COG1561	YicC-like family, N-terminal region
FY145_03980	COG0194	GDP metabolic process
FY145_03995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY145_04000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY145_04010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY145_04025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY145_04045	COG3706	GGDEF domain
FY145_04045	COG5001	Diguanylate cyclase
FY145_04045	COG2203	Gaf domain
FY145_04045	COG4251	negative regulation of phosphorylation
FY145_04050	COG3300	MHYT domain
FY145_04050	COG5001	Diguanylate cyclase
FY145_04055	COG4191	Histidine kinase
FY145_04060	COG4566	intracellular signal transduction
FY145_04070	COG0488	(ABC) transporter
FY145_04075	COG3706	GGDEF domain
FY145_04085	COG0105	UTP biosynthetic process
FY145_04105	COG0314	molybdopterin synthase activity
FY145_04115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY145_04120	COG0322	excinuclease ABC activity
FY145_04125	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_04150	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY145_04155	COG0243	molybdopterin cofactor binding
FY145_04170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY145_04175	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY145_04180	COG2226	methyltransferase
FY145_04185	COG0628	permease
FY145_04195	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY145_04200	COG0248	Ppx GppA phosphatase
FY145_04225	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY145_04235	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY145_04240	COG0477	Major facilitator Superfamily
FY145_04245	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY145_04255	COG0840	transmembrane signaling receptor activity
FY145_04260	COG0659	secondary active sulfate transmembrane transporter activity
FY145_04270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY145_04275	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY145_04285	COG0113	porphobilinogen synthase activity
FY145_04305	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY145_04310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY145_04315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY145_04315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY145_04325	COG1280	lysine exporter protein (LysE YggA)
FY145_04330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY145_04335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY145_04340	COG2814	Major facilitator Superfamily
FY145_04345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY145_04365	COG0416	fatty acid biosynthetic process
FY145_04370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY145_04375	COG0776	regulation of translation
FY145_04410	COG0601	transmembrane transport
FY145_04415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_04420	COG0444	Belongs to the ABC transporter superfamily
FY145_04430	COG0747	negative chemotaxis
FY145_04440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY145_04445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY145_04460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY145_04465	COG0583	DNA-binding transcription factor activity
FY145_04470	COG0737	Belongs to the 5'-nucleotidase family
FY145_04490	COG2897	thiosulfate sulfurtransferase activity
FY145_04505	COG0415	Belongs to the DNA photolyase family
FY145_04515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY145_04545	COG3932	Exopolysaccharide synthesis, ExoD
FY145_04550	COG1238	metal cluster binding
FY145_04625	COG1612	heme a metabolic process
FY145_04635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY145_04640	COG0010	Belongs to the arginase family
FY145_04645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY145_04650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY145_04660	COG1832	CoA-binding protein
FY145_04690	COG2124	cytochrome p450
FY145_04695	COG2199	diguanylate cyclase activity
FY145_04700	COG0740	serine-type endopeptidase activity
FY145_04705	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY145_04710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY145_04720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY145_04745	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY145_04750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY145_04755	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY145_04765	COG0649	NAD binding
FY145_04775	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY145_04780	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY145_04790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY145_04795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY145_04805	COG0713	ATP synthesis coupled electron transport
FY145_04820	COG1007	ATP synthesis coupled electron transport
FY145_04825	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY145_04825	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY145_04840	COG0442	prolyl-tRNA aminoacylation
FY145_04850	COG1136	(ABC) transporter
FY145_04865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY145_04885	COG0784	Response regulator, receiver
FY145_04895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY145_04900	COG0477	Major facilitator Superfamily
FY145_04915	COG0557	exoribonuclease II activity
FY145_04920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY145_04930	COG0758	DNA mediated transformation
FY145_04935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY145_04945	COG0540	Belongs to the ATCase OTCase family
FY145_04960	COG1960	acyl-CoA dehydrogenase activity
FY145_04965	COG0456	acetyltransferase
FY145_04985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY145_04990	COG2824	Alkylphosphonate utilization operon protein PhnA
FY145_04995	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY145_05000	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY145_05005	COG0154	amidase activity
FY145_05010	COG0456	acetyltransferase
FY145_05015	COG3811	Belongs to the UPF0386 family
FY145_05030	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY145_05060	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY145_05065	COG0439	Biotin carboxylase
FY145_05070	COG0511	ligase activity, forming carbon-carbon bonds
FY145_05075	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY145_05085	COG0436	Aminotransferase
FY145_05105	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_05110	COG1530	ribonuclease E activity
FY145_05120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY145_05140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY145_05145	COG0384	phenazine biosynthesis protein PhzF
FY145_05165	COG0633	Ferredoxin
FY145_05180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY145_05185	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY145_05195	COG3768	UPF0283 membrane protein
FY145_05200	COG3106	COG3106 Predicted ATPase
FY145_05230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY145_05265	COG0537	adenosine 5'-monophosphoramidase activity
FY145_05290	COG0052	Belongs to the universal ribosomal protein uS2 family
FY145_05295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY145_05300	COG0528	UMP kinase activity
FY145_05305	COG0233	cytoplasmic translational termination
FY145_05310	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY145_05320	COG0750	zinc metalloprotease
FY145_05325	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY145_05330	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY145_05335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY145_05340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY145_05345	COG3494	Protein of unknown function (DUF1009)
FY145_05350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY145_05355	COG2186	Transcriptional regulator
FY145_05365	COG0765	amino acid transport
FY145_05370	COG0765	amino acid transport
FY145_05380	COG0372	Belongs to the citrate synthase family
FY145_05395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY145_05420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY145_05425	COG1459	type II secretion system
FY145_05480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY145_05485	COG0148	phosphopyruvate hydratase activity
FY145_05495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY145_05500	COG0022	dehydrogenase e1 component
FY145_05500	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY145_05505	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY145_05515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY145_05525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY145_05530	COG0697	spore germination
FY145_05545	COG2867	negative regulation of translational initiation
FY145_05550	COG1546	Belongs to the CinA family
FY145_05555	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY145_05555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY145_05565	COG3852	Histidine kinase
FY145_05570	COG2204	response regulator
FY145_05575	COG5000	phosphorelay sensor kinase activity
FY145_05580	COG2204	response regulator
FY145_05585	COG0569	domain protein
FY145_05590	COG1923	regulation of RNA biosynthetic process
FY145_05595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY145_05600	COG3956	TIGRFAM MazG family protein
FY145_05610	COG1648	precorrin-2 dehydrogenase activity
FY145_05610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY145_05650	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY145_05650	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY145_05655	COG0509	glycine decarboxylation via glycine cleavage system
FY145_05660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY145_05685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY145_05690	COG0564	pseudouridine synthase activity
FY145_05710	COG0251	oxidation-reduction process
FY145_05715	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY145_05725	COG1671	Belongs to the UPF0178 family
FY145_05740	COG0450	alkyl hydroperoxide reductase
FY145_05745	COG0625	glutathione transferase activity
FY145_05755	COG2801	Transposase and inactivated derivatives
FY145_05760	COG0431	NADPH-dependent FMN reductase
FY145_05770	COG0798	PFAM Bile acid sodium symporter
FY145_05775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY145_05790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY145_05790	COG0321	lipoyl(octanoyl) transferase activity
FY145_05795	COG0084	hydrolase, TatD family'
FY145_05800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY145_05810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY145_05860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY145_05865	COG2095	MarC family integral membrane protein
FY145_05870	COG0517	IMP dehydrogenase activity
FY145_05870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY145_05870	COG0617	tRNA 3'-terminal CCA addition
FY145_05880	COG0629	single-stranded DNA binding
FY145_05885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY145_05895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY145_05915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY145_05920	COG1121	(ABC) transporter
FY145_05940	COG0667	Aldo Keto reductase
FY145_05950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY145_06035	COG2239	Acts as a magnesium transporter
FY145_06040	COG0243	molybdopterin cofactor binding
FY145_06050	COG0242	peptide deformylase activity
FY145_06060	COG2205	protein histidine kinase activity
FY145_06060	COG2202	Pas domain
FY145_06070	COG0321	lipoyl(octanoyl) transferase activity
FY145_06075	COG1064	alcohol dehydrogenase
FY145_06105	COG1862	Preprotein translocase
FY145_06125	COG2124	cytochrome p450
FY145_06140	COG0596	Alpha beta hydrolase
FY145_06150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY145_06155	COG0626	cystathionine gamma-synthase activity
FY145_06160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_06165	COG4597	amino acid ABC transporter
FY145_06170	COG0765	amino acid transport
FY145_06175	COG1126	abc transporter atp-binding protein
FY145_06190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY145_06205	COG0436	Aminotransferase
FY145_06235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY145_06245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY145_06250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY145_06255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY145_06270	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY145_06275	COG1489	DNA binding
FY145_06280	COG0024	Methionine aminopeptidase
FY145_06285	COG2003	Belongs to the UPF0758 family
FY145_06300	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY145_06325	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY145_06330	COG0546	phosphoglycolate phosphatase activity
FY145_06340	COG0114	fumarate hydratase activity
FY145_06350	COG0504	CTP synthase activity
FY145_06360	COG0149	triose-phosphate isomerase activity
FY145_06370	COG0187	DNA topoisomerase II activity
FY145_06380	COG0740	serine-type endopeptidase activity
FY145_06390	COG0640	Transcriptional regulator
FY145_06395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY145_06400	COG0745	RESPONSE REGULATOR receiver
FY145_06415	COG3264	Mechanosensitive ion channel
FY145_06415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY145_06480	COG1127	ABC transporter
FY145_06485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY145_06490	COG4948	Mandelate Racemase Muconate Lactonizing
FY145_06500	COG0280	phosphate acetyltransferase
FY145_06500	COG0281	malic enzyme
FY145_06510	COG0778	Nitroreductase
FY145_06515	COG0823	Involved in the tonB-independent uptake of proteins
FY145_06530	COG1368	sulfuric ester hydrolase activity
FY145_06555	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY145_06575	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY145_06595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY145_06610	COG0318	PFAM AMP-dependent synthetase and ligase
FY145_06620	COG0512	Glutamine amidotransferase of anthranilate synthase
FY145_06620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY145_06625	COG0343	queuine tRNA-ribosyltransferase activity
FY145_06630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY145_06645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY145_06660	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY145_06665	COG0134	indole-3-glycerol-phosphate synthase activity
FY145_06670	COG0315	cyclic pyranopterin monophosphate synthase activity
FY145_06675	COG0303	'Molybdopterin
FY145_06680	COG3706	GGDEF domain
FY145_06690	COG0475	glutathione-regulated potassium exporter activity
FY145_06690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY145_06700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY145_06710	COG2814	Major facilitator Superfamily
FY145_06715	COG0746	molybdenum cofactor guanylyltransferase activity
FY145_06720	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY145_06725	COG0739	heme binding
FY145_06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY145_06735	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY145_06740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY145_06745	COG0805	protein transport
FY145_06750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY145_06755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY145_06760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY145_06765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY145_06770	COG1472	Belongs to the glycosyl hydrolase 3 family
FY145_06780	COG0018	arginyl-trna synthetase
FY145_06785	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY145_06810	COG0525	valine-tRNA ligase activity
FY145_06820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY145_06960	COG1525	nuclease
FY145_07035	COG3567	Phage-associated protein, HI1409 family
FY145_07085	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY145_07110	COG0305	Participates in initiation and elongation during chromosome replication
FY145_07110	COG1372	Participates in initiation and elongation during chromosome replication
FY145_07275	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY145_07280	COG1058	Belongs to the CinA family
FY145_07280	COG1546	Belongs to the CinA family
FY145_07285	COG0589	response to stress
FY145_07290	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY145_07295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY145_07305	COG0640	Transcriptional regulator
FY145_07310	COG1914	H( )-stimulated, divalent metal cation uptake system
FY145_07320	COG1132	(ABC) transporter
FY145_07325	COG0628	permease
FY145_07360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY145_07370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY145_07380	COG0302	gtp cyclohydrolase
FY145_07385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY145_07390	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY145_07400	COG0516	GMP reductase activity
FY145_07400	COG0517	IMP dehydrogenase activity
FY145_07435	COG1760	l-serine dehydratase
FY145_07475	COG0583	DNA-binding transcription factor activity
FY145_07490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY145_07490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY145_07500	COG0347	Belongs to the P(II) protein family
FY145_07505	COG0174	glutamine synthetase
FY145_07535	COG0697	spore germination
FY145_07545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY145_07555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY145_07585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY145_07595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY145_07600	COG2186	Transcriptional regulator
FY145_07610	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY145_07615	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY145_07620	COG3845	ABC transporter
FY145_07625	COG1183	phosphatidylcholine synthase activity
FY145_07630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY145_07635	COG0679	Auxin Efflux Carrier
FY145_07640	COG0785	Cytochrome C biogenesis protein
FY145_07660	COG1278	Cold shock
FY145_07710	COG0577	efflux transmembrane transporter activity
FY145_07710	COG1136	(ABC) transporter
FY145_07715	COG0577	efflux transmembrane transporter activity
FY145_07715	COG1136	(ABC) transporter
FY145_07740	COG2151	metal-sulfur cluster biosynthetic enzyme
FY145_07745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY145_07750	COG0719	Fe-S assembly protein
FY145_07755	COG0396	ATPase activity
FY145_07760	COG0719	Fe-S assembly protein
FY145_07765	COG1104	cysteine desulfurase activity
FY145_07770	COG2945	thiolester hydrolase activity
FY145_07775	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY145_07780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY145_07790	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY145_07795	COG2833	Protein of unknown function (DUF455)
FY145_07800	COG0739	heme binding
FY145_07805	COG0513	Belongs to the DEAD box helicase family
FY145_07830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY145_07840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY145_07845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY145_07850	COG0047	phosphoribosylformylglycinamidine synthase activity
FY145_07865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY145_07870	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY145_07890	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY145_07895	COG2814	Major facilitator Superfamily
FY145_07900	COG0483	inositol monophosphate 1-phosphatase activity
FY145_07905	COG0483	inositol monophosphate 1-phosphatase activity
FY145_07910	COG0037	tRNA processing
FY145_07915	COG2066	Belongs to the glutaminase family
FY145_07920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY145_07925	COG0861	Integral membrane protein TerC family
FY145_07940	COG1280	lysine exporter protein (LysE YggA)
FY145_07950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY145_07955	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY145_07965	COG0538	isocitrate dehydrogenase activity
FY145_07975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY145_07980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY145_07985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_07990	COG2313	pseudouridylate synthase activity
FY145_08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_08005	COG4215	(ABC) transporter
FY145_08015	COG5425	PFAM Usg family protein
FY145_08025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY145_08030	COG1522	sequence-specific DNA binding
FY145_08035	COG1573	uracil-dna glycosylase
FY145_08045	COG2202	Pas domain
FY145_08045	COG2205	protein histidine kinase activity
FY145_08050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY145_08055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY145_08060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY145_08075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY145_08080	COG0842	Transport permease protein
FY145_08085	COG1131	(ABC) transporter
FY145_08090	COG0730	response to heat
FY145_08090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY145_08110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY145_08115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY145_08135	COG0129	dihydroxy-acid dehydratase activity
FY145_08140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY145_08145	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY145_08155	COG3739	integral membrane protein
FY145_08160	COG0203	ribosomal protein L17
FY145_08165	COG0202	RNA polymerase activity
FY145_08170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY145_08175	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY145_08180	COG0563	adenylate kinase activity
FY145_08185	COG0201	protein transport
FY145_08190	COG0200	Binds to the 23S rRNA
FY145_08195	COG1841	ribosomal large subunit assembly
FY145_08200	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY145_08205	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY145_08210	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY145_08215	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY145_08220	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY145_08225	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY145_08230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY145_08235	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY145_08240	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY145_08245	COG0255	Belongs to the universal ribosomal protein uL29 family
FY145_08250	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY145_08255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY145_08260	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY145_08265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY145_08270	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY145_08275	COG0089	rRNA binding
FY145_08280	COG0088	Forms part of the polypeptide exit tunnel
FY145_08285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY145_08290	COG0051	transcription antitermination factor activity, RNA binding
FY145_08295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY145_08300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY145_08305	COG0049	tRNA binding
FY145_08310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY145_08330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY145_08335	COG0085	RNA polymerase activity
FY145_08340	COG0222	ribosome binding
FY145_08345	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY145_08350	COG0081	regulation of translation
FY145_08355	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY145_08365	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY145_08375	COG1086	Polysaccharide biosynthesis protein
FY145_08380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY145_08385	COG0861	Integral membrane protein TerC family
FY145_08390	COG3895	Periplasmic Protein
FY145_08410	COG1132	(ABC) transporter
FY145_08415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY145_08435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY145_08470	COG0784	Response regulator, receiver
FY145_08470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_08470	COG2205	protein histidine kinase activity
FY145_08470	COG2198	Histidine kinase
FY145_08475	COG0784	Response regulator, receiver
FY145_08480	COG3920	Histidine kinase
FY145_08480	COG2202	Pas domain
FY145_08485	COG0784	Response regulator, receiver
FY145_08490	COG4251	negative regulation of phosphorylation
FY145_08505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY145_08510	COG1607	acyl-coa hydrolase
FY145_08530	COG2910	NAD(P)H-binding
FY145_08535	COG1733	regulation of RNA biosynthetic process
FY145_08550	COG0556	nucleotide-excision repair
FY145_08560	COG2382	esterase
FY145_08580	COG0484	heat shock protein binding
FY145_08600	COG3706	GGDEF domain
FY145_08620	COG1840	ABC-type Fe3 transport system, periplasmic component
FY145_08625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY145_08640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY145_08650	COG2207	Transcriptional regulator
FY145_08655	COG1064	alcohol dehydrogenase
FY145_08660	COG1252	NADH dehydrogenase
FY145_08665	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY145_08670	COG2197	response regulator
FY145_08675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY145_08710	COG0656	L-ascorbic acid biosynthetic process
FY145_08725	COG0440	acetolactate synthase activity
FY145_08730	COG0028	Belongs to the TPP enzyme family
FY145_08740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY145_08745	COG3830	Belongs to the UPF0237 family
FY145_08745	COG0560	Phosphoserine phosphatase
FY145_08765	COG0330	HflC and HflK could
FY145_08770	COG0330	HflC and HflK could
FY145_08780	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY145_08815	COG0277	FAD linked oxidase domain protein
FY145_08820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY145_08860	COG1335	isochorismatase
FY145_08885	COG2264	protein methyltransferase activity
FY145_08890	COG1999	signal sequence binding
FY145_08900	COG0835	chemotaxis
FY145_08910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY145_08915	COG0583	DNA-binding transcription factor activity
FY145_08925	COG1247	-acetyltransferase
FY145_08935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY145_08940	COG0497	DNA recombination
FY145_08945	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY145_08955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY145_08960	COG0849	cell division
FY145_08965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY145_08970	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY145_08975	COG0477	Major facilitator Superfamily
FY145_08980	COG5001	Diguanylate cyclase
FY145_08985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY145_08990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY145_08995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY145_09005	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY145_09010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY145_09020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY145_09035	COG0275	rRNA processing
FY145_09040	COG2001	Belongs to the MraZ family
FY145_09065	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY145_09095	COG4106	trans-aconitate 2-methyltransferase activity
FY145_09115	COG2226	methyltransferase
FY145_09125	COG2267	carboxylic ester hydrolase activity
FY145_09130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY145_09145	COG0251	oxidation-reduction process
FY145_09160	COG1376	ErfK ybiS ycfS ynhG family protein
FY145_09165	COG2814	Major facilitator Superfamily
FY145_09195	COG1012	belongs to the aldehyde dehydrogenase family
FY145_09200	COG0174	glutamine synthetase
FY145_09205	COG0531	amino acid
FY145_09215	COG1737	Transcriptional regulator
FY145_09220	COG2182	Extracellular solute-binding protein
FY145_09235	COG3842	ATPase activity
FY145_09295	COG2968	Membrane
FY145_09305	COG0432	Pfam Uncharacterised protein family UPF0047
FY145_09320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY145_09325	COG0358	DNA primase activity
FY145_09345	COG0505	Belongs to the CarA family
FY145_09350	COG0534	Mate efflux family protein
FY145_09365	COG2321	neutral zinc metallopeptidase
FY145_09380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY145_09390	COG3706	GGDEF domain
FY145_09405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY145_09415	COG1522	sequence-specific DNA binding
FY145_09420	COG0492	ferredoxin-NADP+ reductase activity
FY145_09425	COG0583	DNA-binding transcription factor activity
FY145_09435	COG1902	pentaerythritol trinitrate reductase activity
FY145_09460	COG0387	Pfam Sodium calcium exchanger
FY145_09465	COG0436	Aminotransferase
FY145_09470	COG2199	diguanylate cyclase activity
FY145_09470	COG2200	EAL domain
FY145_09485	COG1278	Cold shock
FY145_09490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY145_09500	COG1846	Transcriptional regulator
FY145_09505	COG0745	RESPONSE REGULATOR receiver
FY145_09515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY145_09535	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY145_09545	COG1496	oxidoreductase activity
FY145_09560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY145_09570	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY145_09585	COG0840	transmembrane signaling receptor activity
FY145_09590	COG1012	belongs to the aldehyde dehydrogenase family
FY145_09595	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY145_09600	COG5001	Diguanylate cyclase
FY145_09600	COG3300	MHYT domain
FY145_09605	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY145_09610	COG5001	Diguanylate cyclase
FY145_09620	COG0193	aminoacyl-tRNA hydrolase activity
FY145_09630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY145_09655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY145_09665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY145_09665	COG2857	Cytochrome c1
FY145_09685	COG1132	(ABC) transporter
FY145_09695	COG1132	(ABC) transporter
FY145_09705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY145_09720	COG0408	coproporphyrinogen oxidase activity
FY145_09735	COG0617	tRNA 3'-terminal CCA addition
FY145_09750	COG0714	Associated with various cellular activities
FY145_09770	COG0454	-acetyltransferase
FY145_09785	COG0477	Major facilitator Superfamily
FY145_09795	COG0435	Glutathione S-transferase
FY145_09800	COG0494	nUDIX hydrolase
FY145_09810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY145_09815	COG3135	benzoate transporter
FY145_09840	COG0740	serine-type endopeptidase activity
FY145_09855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY145_09860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY145_09885	COG4175	Glycine betaine
FY145_09905	COG1435	thymidine kinase activity
FY145_09930	COG1629	transport
FY145_09930	COG4771	TonB-dependent receptor
FY145_09940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY145_09940	COG0512	Glutamine amidotransferase of anthranilate synthase
FY145_09955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY145_09965	COG0366	Alpha amylase catalytic
FY145_09970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_09990	COG1160	GTP binding
FY145_10010	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY145_10020	COG0024	Methionine aminopeptidase
FY145_10030	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_10050	COG0583	DNA-binding transcription factor activity
FY145_10065	COG0402	S-adenosylhomocysteine deaminase activity
FY145_10075	COG1304	FMN binding
FY145_10085	COG1309	transcriptional regulator
FY145_10090	COG1686	Belongs to the peptidase S11 family
FY145_10100	COG2351	hydroxyisourate hydrolase activity
FY145_10105	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY145_10130	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY145_10140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_10140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY145_10150	COG0513	Belongs to the DEAD box helicase family
FY145_10160	COG2259	Doxx family
FY145_10165	COG1376	ErfK ybiS ycfS ynhG family protein
FY145_10175	COG2308	Evidence 4 Homologs of previously reported genes of
FY145_10185	COG1305	Transglutaminase-like
FY145_10210	COG4214	carbohydrate transport
FY145_10220	COG4213	ABC transporter substrate-binding protein
FY145_10275	COG2948	multi-organism process
FY145_10285	COG3701	Conjugal transfer protein
FY145_10290	COG3846	protein secretion by the type IV secretion system
FY145_10305	COG3451	type IV secretory pathway VirB4
FY145_10320	COG4962	Type ii secretion system protein e
FY145_10345	COG0583	DNA-binding transcription factor activity
FY145_10355	COG1566	PFAM secretion protein HlyD family protein
FY145_10370	COG2207	Transcriptional regulator
FY145_10375	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_10385	COG0583	DNA-binding transcription factor activity
FY145_10395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY145_10410	COG0583	DNA-binding transcription factor activity
FY145_10420	COG0741	lytic transglycosylase activity
FY145_10445	COG1192	Involved in chromosome partitioning
FY145_10480	COG2814	Major facilitator Superfamily
FY145_10490	COG5489	Protein of unknown function (DUF736)
FY145_10505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY145_10535	COG1204	response to ionizing radiation
FY145_10550	COG0514	ATP-dependent DNA helicase (RecQ)
FY145_10600	COG0583	DNA-binding transcription factor activity
FY145_10605	COG1902	pentaerythritol trinitrate reductase activity
FY145_10610	COG0583	DNA-binding transcription factor activity
FY145_10625	COG1335	isochorismatase
FY145_10630	COG0583	DNA-binding transcription factor activity
FY145_10635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY145_10645	COG4584	PFAM Integrase catalytic
FY145_10660	COG0840	transmembrane signaling receptor activity
FY145_10675	COG0646	methionine synthase
FY145_10675	COG1410	methionine synthase
FY145_10690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_10720	COG1215	transferase activity, transferring glycosyl groups
FY145_10750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY145_10765	COG2346	COG2346, Truncated hemoglobins
FY145_10785	COG1309	transcriptional regulator
FY145_10800	COG0494	nUDIX hydrolase
FY145_10810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_10815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_10845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY145_10850	COG0830	nickel cation binding
FY145_10855	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY145_10870	COG0804	urea catabolic process
FY145_10875	COG1442	glycosyl transferase family 8
FY145_10880	COG3755	Protein conserved in bacteria
FY145_10890	COG0832	Belongs to the urease beta subunit family
FY145_10895	COG3813	Protein conserved in bacteria
FY145_10900	COG0831	urea catabolic process
FY145_10905	COG0829	nickel cation binding
FY145_10935	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY145_10950	COG0174	glutamine synthetase
FY145_10955	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_10960	COG5002	protein histidine kinase activity
FY145_10960	COG2198	Histidine kinase
FY145_10960	COG0784	Response regulator, receiver
FY145_10975	COG0726	polysaccharide deacetylase
FY145_11010	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY145_11085	COG0564	pseudouridine synthase activity
FY145_11095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY145_11105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY145_11130	COG0346	lactoylglutathione lyase activity
FY145_11140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY145_11150	COG2832	Protein of unknown function (DUF454)
FY145_11155	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY145_11160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_11165	COG4558	Periplasmic binding protein
FY145_11175	COG3721	Heme iron utilization protein
FY145_11190	COG3655	Transcriptional regulator
FY145_11215	COG2205	protein histidine kinase activity
FY145_11255	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_11260	COG4605	iron ion homeostasis
FY145_11265	COG4604	ABC transporter, ATP-binding protein
FY145_11270	COG0783	Belongs to the Dps family
FY145_11285	COG0840	transmembrane signaling receptor activity
FY145_11285	COG2972	Histidine kinase
FY145_11290	COG0656	L-ascorbic acid biosynthetic process
FY145_11295	COG2814	Major facilitator Superfamily
FY145_11305	COG0583	DNA-binding transcription factor activity
FY145_11310	COG0657	acetylesterase activity
FY145_11315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_11335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY145_11340	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY145_11345	COG0288	reversible hydration of carbon dioxide
FY145_11355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY145_11375	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY145_11380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY145_11385	COG0778	Nitroreductase
FY145_11390	COG2267	carboxylic ester hydrolase activity
FY145_11395	COG0251	oxidation-reduction process
FY145_11400	COG1335	isochorismatase
FY145_11405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_11415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_11430	COG1175	transmembrane transport
FY145_11435	COG0395	ABC-type sugar transport system, permease component
FY145_11440	COG3842	ATPase activity
FY145_11445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_11455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY145_11470	COG4608	Belongs to the ABC transporter superfamily
FY145_11475	COG0444	Belongs to the ABC transporter superfamily
FY145_11480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_11485	COG0601	transmembrane transport
FY145_11540	COG2159	amidohydrolase
FY145_11545	COG1960	acyl-CoA dehydrogenase activity
FY145_11575	COG0745	RESPONSE REGULATOR receiver
FY145_11585	COG1902	pentaerythritol trinitrate reductase activity
FY145_11585	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY145_11590	COG3842	ATPase activity
FY145_11600	COG1840	ABC-type Fe3 transport system, periplasmic component
FY145_11605	COG1840	ABC-type Fe3 transport system, periplasmic component
FY145_11610	COG0745	RESPONSE REGULATOR receiver
FY145_11620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY145_11625	COG0583	DNA-binding transcription factor activity
FY145_11630	COG1278	Cold shock
FY145_11670	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY145_11675	COG1309	transcriptional regulator
FY145_11680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_11685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY145_11695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY145_11700	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY145_11720	COG0583	DNA-binding transcription factor activity
FY145_11725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_11730	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY145_11735	COG4149	molybdate abc transporter
FY145_11740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY145_11755	COG2022	thiamine diphosphate biosynthetic process
FY145_11770	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY145_11780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY145_11790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY145_11810	COG1132	(ABC) transporter
FY145_11815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY145_11860	COG4166	transmembrane transport
FY145_11865	COG0601	transmembrane transport
FY145_11870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_11885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY145_11890	COG3142	Participates in the control of copper homeostasis
FY145_11895	COG2814	Major facilitator Superfamily
FY145_11910	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_11915	COG1737	Transcriptional regulator
FY145_11925	COG3842	ATPase activity
FY145_11935	COG0395	ABC-type sugar transport system, permease component
FY145_11955	COG2188	Transcriptional regulator
FY145_11960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY145_11965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY145_11970	COG1940	carbohydrate kinase activity
FY145_11980	COG0671	phosphoesterase, PA-phosphatase related
FY145_11985	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY145_11990	COG0156	8-amino-7-oxononanoate synthase activity
FY145_12000	COG0729	surface antigen
FY145_12010	COG0835	chemotaxis
FY145_12020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY145_12025	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY145_12030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY145_12035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY145_12040	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY145_12045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY145_12060	COG4974	Belongs to the 'phage' integrase family
FY145_12085	COG1280	lysine exporter protein (LysE YggA)
FY145_12095	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY145_12100	COG0567	Dehydrogenase, E1 component
FY145_12105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY145_12110	COG0045	succinate-CoA ligase (ADP-forming) activity
FY145_12115	COG0039	L-malate dehydrogenase activity
FY145_12120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY145_12170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY145_12175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY145_12180	COG0181	hydroxymethylbilane synthase activity
FY145_12220	COG1872	DUF167
FY145_12225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY145_12235	COG1217	gtp-binding protein TYPA
FY145_12240	COG0339	signal peptide processing
FY145_12245	COG1846	Transcriptional regulator
FY145_12255	COG0137	argininosuccinate synthase activity
FY145_12265	COG1280	lysine exporter protein (LysE YggA)
FY145_12270	COG1122	ATPase activity
FY145_12275	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY145_12285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY145_12300	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY145_12305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY145_12310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY145_12320	COG4181	ATPase activity
FY145_12330	COG0670	Belongs to the BI1 family
FY145_12345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY145_12350	COG4133	protoheme IX ABC transporter activity
FY145_12355	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY145_12360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY145_12385	COG2917	probably involved in intracellular septation
FY145_12390	COG0552	protein localization to endoplasmic reticulum
FY145_12395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY145_12400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY145_12415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY145_12420	COG0287	Prephenate dehydrogenase
FY145_12420	COG1605	Chorismate mutase
FY145_12425	COG0228	four-way junction DNA binding
FY145_12430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY145_12435	COG0336	Belongs to the RNA methyltransferase TrmD family
FY145_12445	COG0335	large ribosomal subunit rRNA binding
FY145_12450	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY145_12455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_12470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY145_12490	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY145_12510	COG0488	(ABC) transporter
FY145_12520	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY145_12530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY145_12535	COG0142	geranyltranstransferase activity
FY145_12540	COG2885	chlorophyll binding
FY145_12545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY145_12550	COG2223	nitrite transmembrane transporter activity
FY145_12555	COG1349	DNA-binding transcription factor activity
FY145_12560	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY145_12565	COG2197	response regulator
FY145_12570	COG1132	(ABC) transporter
FY145_12580	COG3459	Glycosyltransferase 36 associated
FY145_12585	COG1473	amidohydrolase
FY145_12590	COG0579	oxidoreductase
FY145_12600	COG0129	dihydroxy-acid dehydratase activity
FY145_12605	COG2084	Dehydrogenase
FY145_12610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY145_12615	COG0277	FAD linked oxidase domain protein
FY145_12620	COG2186	Transcriptional regulator
FY145_12630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY145_12635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY145_12640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY145_12645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY145_12655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY145_12660	COG0495	leucyl-tRNA aminoacylation
FY145_12675	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY145_12680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY145_12695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY145_12700	COG1946	Acyl-CoA thioesterase
FY145_12705	COG0347	Belongs to the P(II) protein family
FY145_12710	COG0004	ammonium transporteR
FY145_12715	COG1674	ftsk spoiiie
FY145_12720	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY145_12735	COG0745	RESPONSE REGULATOR receiver
FY145_12745	COG1329	Transcriptional regulator
FY145_12755	COG2270	Major facilitator Superfamily
FY145_12770	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_12785	COG0494	nUDIX hydrolase
FY145_12790	COG2861	carbohydrate metabolic process
FY145_12795	COG0793	Belongs to the peptidase S41A family
FY145_12805	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY145_12810	COG0799	negative regulation of ribosome biogenesis
FY145_12815	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY145_12820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY145_12825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY145_12830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY145_12845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY145_12850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY145_12875	COG0066	3-isopropylmalate dehydratase activity
FY145_12880	COG0473	3-isopropylmalate dehydrogenase activity
FY145_12885	COG1858	cytochrome C peroxidase
FY145_12890	COG1797	cobyrinic acid a,c-diamide synthase activity
FY145_12900	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY145_12965	COG1492	cobalamin metabolic process
FY145_12980	COG4948	Mandelate Racemase Muconate Lactonizing
FY145_12985	COG3254	rhamnose metabolic process
FY145_12990	COG0246	Mannitol dehydrogenase
FY145_12995	COG1063	alcohol dehydrogenase
FY145_13020	COG1129	ABC transporter
FY145_13025	COG2186	Transcriptional regulator
FY145_13030	COG2721	sulfolactate sulfo-lyase activity
FY145_13035	COG0138	bifunctional purine biosynthesis protein purh
FY145_13045	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY145_13045	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY145_13050	COG0501	Belongs to the peptidase M48B family
FY145_13070	COG0357	Ribosomal RNA small subunit methyltransferase G
FY145_13075	COG0445	tRNA wobble uridine modification
FY145_13080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY145_13085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY145_13090	COG1981	membrane
FY145_13095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY145_13100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY145_13105	COG0424	maF-like protein
FY145_13110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY145_13115	COG0237	dephospho-CoA kinase activity
FY145_13125	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY145_13130	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY145_13140	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY145_13165	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY145_13180	COG0135	phosphoribosylanthranilate isomerase activity
FY145_13185	COG0133	tryptophan synthase activity
FY145_13190	COG0159	tryptophan synthase activity
FY145_13195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY145_13210	COG1074	ATP-dependent DNA helicase activity
FY145_13220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY145_13225	COG0802	atpase or kinase
FY145_13230	COG2205	protein histidine kinase activity
FY145_13235	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY145_13240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY145_13245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY145_13245	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY145_13250	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY145_13255	COG0642	Histidine kinase
FY145_13260	COG0745	RESPONSE REGULATOR receiver
FY145_13265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY145_13275	COG1652	LysM domain
FY145_13280	COG1072	(Pantothenic acid kinase))
FY145_13285	COG0140	phosphoribosyl-ATP diphosphatase activity
FY145_13290	COG0107	imidazoleglycerol-phosphate synthase activity
FY145_13295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY145_13300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY145_13310	COG0131	Imidazoleglycerol-phosphate dehydratase
FY145_13315	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY145_13320	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY145_13330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY145_13345	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY145_13355	COG1643	Atp-dependent helicase
FY145_13400	COG1940	carbohydrate kinase activity
FY145_13420	COG1072	(Pantothenic acid kinase))
FY145_13430	COG1780	Probably involved in ribonucleotide reductase function
FY145_13450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY145_13480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_13490	COG2813	Specifically methylates the guanine in position
FY145_13495	COG1185	polyribonucleotide nucleotidyltransferase activity
FY145_13500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY145_13505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY145_13510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY145_13515	COG3064	Membrane
FY145_13515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY145_13530	COG0779	Required for maturation of 30S ribosomal subunits
FY145_13535	COG2814	Major facilitator Superfamily
FY145_13545	COG2951	lytic endotransglycosylase activity
FY145_13550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY145_13560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY145_13565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY145_13580	COG2816	NAD+ diphosphatase activity
FY145_13585	COG0077	Prephenate dehydratase
FY145_13585	COG1605	Chorismate mutase
FY145_13590	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY145_13595	COG3474	cytochrome
FY145_13605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY145_13610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY145_13615	COG1278	Cold shock
FY145_13620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY145_13630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY145_13630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY145_13635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY145_13665	COG2900	Belongs to the SlyX family
FY145_13675	COG0484	heat shock protein binding
FY145_13680	COG0443	Heat shock 70 kDa protein
FY145_13695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY145_13700	COG1744	ABC transporter substrate-binding protein PnrA-like
FY145_13705	COG3845	ABC transporter
FY145_13710	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY145_13715	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY145_13720	COG0295	cytidine deaminase activity
FY145_13725	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY145_13730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY145_13735	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY145_13745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY145_13750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY145_13755	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY145_13765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY145_13770	COG1845	cytochrome c oxidase, subunit III
FY145_13775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY145_13780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY145_13785	COG0477	Major facilitator Superfamily
FY145_13790	COG0067	glutamate synthase
FY145_13790	COG0069	glutamate synthase activity
FY145_13790	COG0070	glutamate synthase
FY145_13795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY145_13810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY145_13820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY145_13850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_13870	COG0848	biopolymer transport protein
FY145_13880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY145_13895	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY145_13900	COG3454	Phosphonate metabolism
FY145_13905	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY145_13910	COG3639	organic phosphonate transmembrane transporter activity
FY145_13915	COG3639	organic phosphonate transmembrane transporter activity
FY145_13925	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY145_13935	COG4778	phosphonate C-P lyase system protein PhnL
FY145_13940	COG4107	phosphonate C-P lyase system protein PhnK
FY145_13945	COG3627	carbon phosphorus lyase activity
FY145_13950	COG3626	phosphonate metabolism
FY145_13955	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY145_13960	COG3624	Phosphonate C-P lyase system protein PhnG
FY145_13965	COG2188	Transcriptional regulator
FY145_13970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY145_13975	COG0837	glucose binding
FY145_13980	COG1803	Methylglyoxal synthase
FY145_13985	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY145_13990	COG4166	transmembrane transport
FY145_13995	COG4174	ABC transporter (Permease)
FY145_14000	COG4239	(ABC) transporter, permease
FY145_14005	COG4172	Belongs to the ABC transporter superfamily
FY145_14010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_14015	COG0174	glutamine synthetase
FY145_14020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_14025	COG3265	gluconokinase activity
FY145_14030	COG1174	glycine betaine transport
FY145_14035	COG1125	glycine betaine transport
FY145_14040	COG1174	glycine betaine transport
FY145_14045	COG1732	Glycine betaine
FY145_14055	COG1959	2 iron, 2 sulfur cluster binding
FY145_14060	COG1840	ABC-type Fe3 transport system, periplasmic component
FY145_14070	COG4269	membrane
FY145_14085	COG0697	spore germination
FY145_14100	COG0791	NLP P60 protein
FY145_14110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY145_14115	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY145_14150	COG4964	Belongs to the GSP D family
FY145_14195	COG3422	double-strand break repair
FY145_14200	COG3757	hydrolase, family 25
FY145_14205	COG0697	spore germination
FY145_14210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY145_14225	COG0492	ferredoxin-NADP+ reductase activity
FY145_14240	COG0481	GTPase activity
FY145_14245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY145_14260	COG1396	sequence-specific DNA binding
FY145_14275	COG1917	Cupin 2, conserved barrel domain protein
FY145_14275	COG2169	Transcriptional regulator
FY145_14280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY145_14305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY145_14310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY145_14315	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY145_14325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY145_14330	COG0072	phenylalanine-tRNA ligase activity
FY145_14330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY145_14335	COG0667	Aldo Keto reductase
FY145_14355	COG4977	sequence-specific DNA binding
FY145_14380	COG1570	exodeoxyribonuclease VII activity
FY145_14385	COG4948	Mandelate Racemase Muconate Lactonizing
FY145_14395	COG1846	Transcriptional regulator
FY145_14405	COG2309	aminopeptidase activity
FY145_14415	COG1393	Belongs to the ArsC family
FY145_14430	COG1309	transcriptional regulator
FY145_14440	COG0519	Catalyzes the synthesis of GMP from XMP
FY145_14440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY145_14455	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY145_14485	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY145_14495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY145_14505	COG1968	undecaprenyl-diphosphatase activity
FY145_14520	COG0284	orotidine-5'-phosphate decarboxylase activity
FY145_14530	COG3963	phosphatidate phosphatase activity
FY145_14540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY145_14545	COG0792	nuclease activity
FY145_14560	COG1175	transmembrane transport
FY145_14565	COG0395	ABC-type sugar transport system, permease component
FY145_14570	COG3842	ATPase activity
FY145_14580	COG0189	ligase activity
FY145_14590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY145_14595	COG1280	lysine exporter protein (LysE YggA)
FY145_14600	COG0756	dUTP diphosphatase activity
FY145_14605	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY145_14610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY145_14625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY145_14630	COG2226	methyltransferase
FY145_14635	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY145_14640	COG1024	Enoyl-CoA hydratase
FY145_14645	COG0268	Binds directly to 16S ribosomal RNA
FY145_14655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY145_14685	COG1278	Cold shock
FY145_14720	COG0411	ABC transporter
FY145_14725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY145_14730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY145_14735	COG1454	alcohol dehydrogenase
FY145_14740	COG0747	negative chemotaxis
FY145_14745	COG0601	transmembrane transport
FY145_14755	COG4608	Belongs to the ABC transporter superfamily
FY145_14760	COG1349	DNA-binding transcription factor activity
FY145_14765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY145_14790	COG4302	ethanolamine ammonia-lyase activity
FY145_14795	COG0025	NhaP-type Na H and K H
FY145_14800	COG4106	trans-aconitate 2-methyltransferase activity
FY145_14810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_14815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_14820	COG0601	transmembrane transport
FY145_14845	COG4172	Belongs to the ABC transporter superfamily
FY145_14880	COG0596	Alpha beta hydrolase
FY145_14895	COG1764	response to oxidative stress
FY145_14905	COG0596	Alpha beta hydrolase
FY145_14920	COG0783	Belongs to the Dps family
FY145_14925	COG0243	molybdopterin cofactor binding
FY145_14935	COG4566	intracellular signal transduction
FY145_14940	COG4566	intracellular signal transduction
FY145_14970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY145_14980	COG1414	Transcriptional regulator
FY145_14995	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_15015	COG1522	sequence-specific DNA binding
FY145_15040	COG0628	permease
FY145_15050	COG2235	arginine
FY145_15085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY145_15095	COG0702	epimerase
FY145_15100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY145_15105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_15110	COG0745	RESPONSE REGULATOR receiver
FY145_15115	COG5002	protein histidine kinase activity
FY145_15130	COG2233	PERMEase
FY145_15190	COG0395	ABC-type sugar transport system, permease component
FY145_15195	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_15205	COG3842	ATPase activity
FY145_15240	COG1653	transport
FY145_15250	COG0395	ABC-type sugar transport system, permease component
FY145_15255	COG3842	ATPase activity
FY145_15270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY145_15275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_15280	COG1116	anion transmembrane transporter activity
FY145_15285	COG0395	ABC-type sugar transport system, permease component
FY145_15290	COG1175	transmembrane transport
FY145_15320	COG1609	Transcriptional regulator
FY145_15335	COG1082	Xylose isomerase domain protein TIM barrel
FY145_15340	COG3842	ATPase activity
FY145_15345	COG0395	ABC-type sugar transport system, permease component
FY145_15350	COG1175	transmembrane transport
FY145_15355	COG1653	transport
FY145_15360	COG1309	transcriptional regulator
FY145_15365	COG0673	inositol 2-dehydrogenase activity
FY145_15380	COG0673	inositol 2-dehydrogenase activity
FY145_15385	COG1278	Cold shock
FY145_15395	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY145_15415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY145_15420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY145_15435	COG3842	ATPase activity
FY145_15440	COG0395	ABC-type sugar transport system, permease component
FY145_15445	COG1175	transmembrane transport
FY145_15455	COG3618	amidohydrolase
FY145_15460	COG4948	Mandelate Racemase Muconate Lactonizing
FY145_15465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_15470	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_15475	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY145_15480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY145_15485	COG2186	Transcriptional regulator
FY145_15500	COG0667	Aldo Keto reductase
FY145_15530	COG4977	sequence-specific DNA binding
FY145_15535	COG2223	nitrite transmembrane transporter activity
FY145_15540	COG1609	Transcriptional regulator
FY145_15545	COG1063	alcohol dehydrogenase
FY145_15550	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_15560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_15565	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY145_15570	COG1175	transmembrane transport
FY145_15575	COG0395	ABC-type sugar transport system, permease component
FY145_15590	COG0395	ABC-type sugar transport system, permease component
FY145_15600	COG2182	Extracellular solute-binding protein
FY145_15605	COG0626	cystathionine gamma-synthase activity
FY145_15620	COG0454	-acetyltransferase
FY145_15625	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY145_15635	COG1121	(ABC) transporter
FY145_15640	COG0523	cobalamin synthesis protein
FY145_15655	COG0523	cobalamin synthesis protein
FY145_15660	COG1653	transport
FY145_15665	COG1175	transmembrane transport
FY145_15670	COG0395	ABC-type sugar transport system, permease component
FY145_15675	COG3842	ATPase activity
FY145_15685	COG3047	cAMP biosynthetic process
FY145_15710	COG0583	DNA-binding transcription factor activity
FY145_15715	COG1879	ABC-type sugar transport system periplasmic component
FY145_15720	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_15725	COG1129	ABC transporter
FY145_15735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY145_15740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_15750	COG3257	ureidoglycine aminohydrolase activity
FY145_15760	COG5001	Diguanylate cyclase
FY145_15765	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY145_15775	COG0747	negative chemotaxis
FY145_15780	COG0601	transmembrane transport
FY145_15785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_15795	COG4608	Belongs to the ABC transporter superfamily
FY145_15800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY145_15815	COG0346	lactoylglutathione lyase activity
FY145_15825	COG0129	dihydroxy-acid dehydratase activity
FY145_15830	COG1879	ABC-type sugar transport system periplasmic component
FY145_15835	COG1129	ABC transporter
FY145_15840	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_15845	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_15850	COG2186	Transcriptional regulator
FY145_15865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY145_15870	COG0587	DNA-directed DNA polymerase activity
FY145_15900	COG0673	inositol 2-dehydrogenase activity
FY145_15910	COG3842	ATPase activity
FY145_15915	COG0395	ABC-type sugar transport system, permease component
FY145_15920	COG1175	transmembrane transport
FY145_15925	COG1653	transport
FY145_15935	COG0673	inositol 2-dehydrogenase activity
FY145_15950	COG5001	Diguanylate cyclase
FY145_15960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_15965	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY145_15970	COG2894	cell division
FY145_15975	COG0850	regulation of cytokinetic process
FY145_15980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY145_15985	COG2186	Transcriptional regulator
FY145_15990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY145_16000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY145_16005	COG1063	alcohol dehydrogenase
FY145_16010	COG1312	Catalyzes the dehydration of D-mannonate
FY145_16030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY145_16035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY145_16035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY145_16040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_16055	COG0625	glutathione transferase activity
FY145_16060	COG4172	Belongs to the ABC transporter superfamily
FY145_16065	COG1921	L-seryl-tRNASec selenium transferase activity
FY145_16080	COG3964	amidohydrolase
FY145_16090	COG0601	transmembrane transport
FY145_16095	COG0747	negative chemotaxis
FY145_16100	COG0438	transferase activity, transferring glycosyl groups
FY145_16135	COG4989	oxidoreductase activity
FY145_16145	COG2188	Transcriptional regulator
FY145_16150	COG3842	ATPase activity
FY145_16155	COG1653	transport
FY145_16160	COG1175	transmembrane transport
FY145_16165	COG0395	ABC-type sugar transport system, permease component
FY145_16170	COG1501	Belongs to the glycosyl hydrolase 31 family
FY145_16180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_16185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY145_16190	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY145_16195	COG0352	thiamine-phosphate diphosphorylase activity
FY145_16200	COG0351	phosphomethylpyrimidine kinase
FY145_16205	COG1522	sequence-specific DNA binding
FY145_16210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY145_16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_16230	COG2204	response regulator
FY145_16235	COG4191	Histidine kinase
FY145_16240	COG1301	dicarboxylic acid transport
FY145_16245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY145_16250	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_16260	COG1473	amidohydrolase
FY145_16280	COG1215	transferase activity, transferring glycosyl groups
FY145_16290	COG2942	2-epimerase
FY145_16315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY145_16325	COG2197	response regulator
FY145_16355	COG3307	-O-antigen
FY145_16360	COG1596	polysaccharide export
FY145_16365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY145_16375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY145_16380	COG0840	transmembrane signaling receptor activity
FY145_16385	COG1376	ErfK ybiS ycfS ynhG family protein
FY145_16395	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_16405	COG2094	Belongs to the DNA glycosylase MPG family
FY145_16420	COG1609	Transcriptional regulator
FY145_16425	COG1653	transport
FY145_16440	COG3842	ATPase activity
FY145_16450	COG0673	inositol 2-dehydrogenase activity
FY145_16455	COG0602	queuosine metabolic process
FY145_16460	COG0720	synthase
FY145_16465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY145_16470	COG0673	inositol 2-dehydrogenase activity
FY145_16485	COG0395	ABC-type sugar transport system, permease component
FY145_16490	COG1175	transmembrane transport
FY145_16515	COG0583	DNA-binding transcription factor activity
FY145_16520	COG0280	phosphate acetyltransferase
FY145_16520	COG0281	malic enzyme
FY145_16535	COG0765	amino acid transport
FY145_16540	COG1126	abc transporter atp-binding protein
FY145_16545	COG2079	MmgE PrpD family protein
FY145_16550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_16560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_16575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY145_16585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY145_16590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY145_16595	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_16600	COG1129	ABC transporter
FY145_16615	COG1473	amidohydrolase
FY145_16620	COG0747	negative chemotaxis
FY145_16635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_16640	COG0601	transmembrane transport
FY145_16645	COG0583	DNA-binding transcription factor activity
FY145_16650	COG1446	asparaginase
FY145_16665	COG0747	negative chemotaxis
FY145_16685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_16690	COG0601	transmembrane transport
FY145_16695	COG2197	response regulator
FY145_16700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY145_16705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY145_16715	COG3842	ATPase activity
FY145_16720	COG0395	ABC-type sugar transport system, permease component
FY145_16725	COG1175	transmembrane transport
FY145_16735	COG0673	inositol 2-dehydrogenase activity
FY145_16740	COG0673	inositol 2-dehydrogenase activity
FY145_16760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_16765	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY145_16785	COG1595	DNA-templated transcription, initiation
FY145_16790	COG1120	ATPase activity
FY145_16795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_16810	COG2226	methyltransferase
FY145_16820	COG1120	ATPase activity
FY145_16825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_16870	COG1012	belongs to the aldehyde dehydrogenase family
FY145_16875	COG0473	3-isopropylmalate dehydrogenase activity
FY145_16880	COG1012	belongs to the aldehyde dehydrogenase family
FY145_16885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_16920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_16925	COG4172	Belongs to the ABC transporter superfamily
FY145_16930	COG1522	sequence-specific DNA binding
FY145_16940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_16955	COG0583	DNA-binding transcription factor activity
FY145_16965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_16970	COG1126	abc transporter atp-binding protein
FY145_16980	COG1473	amidohydrolase
FY145_16985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_16990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_16995	COG1959	2 iron, 2 sulfur cluster binding
FY145_17005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY145_17010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_17040	COG1960	acyl-CoA dehydrogenase activity
FY145_17050	COG0747	negative chemotaxis
FY145_17065	COG0444	Belongs to the ABC transporter superfamily
FY145_17075	COG0667	Aldo Keto reductase
FY145_17085	COG0583	DNA-binding transcription factor activity
FY145_17090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_17095	COG4166	transmembrane transport
FY145_17110	COG0747	negative chemotaxis
FY145_17115	COG1473	amidohydrolase
FY145_17120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_17135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_17140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_17150	COG1733	regulation of RNA biosynthetic process
FY145_17155	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_17290	COG4373	Mu-like prophage FluMu protein gp28
FY145_17295	COG4383	Mu-like prophage protein gp29
FY145_17300	COG2369	cell adhesion
FY145_17430	COG4608	Belongs to the ABC transporter superfamily
FY145_17435	COG0444	Belongs to the ABC transporter superfamily
FY145_17445	COG0601	transmembrane transport
FY145_17455	COG2186	Transcriptional regulator
FY145_17470	COG0300	oxidoreductase activity
FY145_17480	COG3453	Protein conserved in bacteria
FY145_17480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY145_17485	COG0640	Transcriptional regulator
FY145_17495	COG2391	methyltransferase activity
FY145_17500	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY145_17510	COG0022	dehydrogenase e1 component
FY145_17520	COG1960	acyl-CoA dehydrogenase activity
FY145_17525	COG0183	Belongs to the thiolase family
FY145_17535	COG1960	acyl-CoA dehydrogenase activity
FY145_17540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY145_17560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY145_17565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY145_17570	COG4952	isomerase
FY145_17575	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_17575	COG3347	Dehydrogenase
FY145_17580	COG1349	DNA-binding transcription factor activity
FY145_17590	COG1129	ABC transporter
FY145_17595	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_17600	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_17605	COG3254	rhamnose metabolic process
FY145_17620	COG2264	protein methyltransferase activity
FY145_17625	COG5001	Diguanylate cyclase
FY145_17640	COG4335	DNA alkylation repair
FY145_17645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY145_17650	COG4208	sulfate ABC transporter
FY145_17660	COG4150	thiosulfate binding
FY145_17665	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY145_17680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY145_17690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY145_17700	COG1040	competence protein
FY145_17705	COG2226	methyltransferase
FY145_17720	COG0494	nUDIX hydrolase
FY145_17730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY145_17735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY145_17740	COG0653	protein targeting
FY145_17745	COG0697	spore germination
FY145_17810	COG2244	polysaccharide biosynthetic process
FY145_17825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY145_17835	COG0489	protein tyrosine kinase activity
FY145_17835	COG3206	protein involved in exopolysaccharide biosynthesis
FY145_17855	COG0438	transferase activity, transferring glycosyl groups
FY145_17860	COG0438	transferase activity, transferring glycosyl groups
FY145_17875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY145_17880	COG2273	Hydrolase Family 16
FY145_17880	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY145_17895	COG3842	ATPase activity
FY145_17900	COG3833	ABC-type maltose transport systems, permease component
FY145_17955	COG1396	sequence-specific DNA binding
FY145_17965	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY145_17970	COG1129	ABC transporter
FY145_17975	COG4214	carbohydrate transport
FY145_17980	COG4213	ABC transporter substrate-binding protein
FY145_17995	COG0346	lactoylglutathione lyase activity
FY145_18000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY145_18000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY145_18005	COG4770	biotin carboxylase activity
FY145_18020	COG0625	glutathione transferase activity
FY145_18025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY145_18030	COG1396	sequence-specific DNA binding
FY145_18030	COG3800	Transcriptional regulator
FY145_18040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY145_18050	COG0300	oxidoreductase activity
FY145_18060	COG2096	Adenosyltransferase
FY145_18070	COG2086	electron transfer activity
FY145_18080	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY145_18090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY145_18095	COG0165	Argininosuccinate lyase
FY145_18130	COG2884	Cell division ATP-binding protein ftsE
FY145_18150	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY145_18160	COG0287	Prephenate dehydrogenase
FY145_18165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY145_18170	COG2226	methyltransferase
FY145_18175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY145_18195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY145_18200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY145_18240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY145_18245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY145_18255	COG4974	Belongs to the 'phage' integrase family
FY145_18260	COG0825	malonyl-CoA metabolic process
FY145_18265	COG3034	peptidoglycan biosynthetic process
FY145_18270	COG0425	Belongs to the sulfur carrier protein TusA family
FY145_18270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY145_18275	COG0523	cobalamin synthesis protein
FY145_18280	COG1686	Belongs to the peptidase S11 family
FY145_18285	COG1473	amidohydrolase
FY145_18295	COG4953	penicillin-binding protein 1C
FY145_18300	COG2373	Large extracellular alpha-helical protein
FY145_18305	COG2835	tetraacyldisaccharide 4'-kinase activity
FY145_18335	COG0482	sulfurtransferase activity
FY145_18350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY145_18365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY145_18370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY145_18375	COG0037	tRNA processing
FY145_18385	COG2885	chlorophyll binding
FY145_18390	COG0823	Involved in the tonB-independent uptake of proteins
FY145_18410	COG0824	Thioesterase
FY145_18420	COG0494	nUDIX hydrolase
FY145_18435	COG2255	four-way junction helicase activity
FY145_18440	COG0632	four-way junction helicase activity
FY145_18445	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY145_18450	COG0840	transmembrane signaling receptor activity
FY145_18455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_18460	COG0217	transcriptional regulatory protein
FY145_18475	COG1692	metallophosphoesterase
FY145_18485	COG1253	flavin adenine dinucleotide binding
FY145_18525	COG0126	phosphoglycerate kinase activity
FY145_18530	COG3588	fructose-bisphosphate aldolase
FY145_18550	COG0254	rRNA binding
FY145_18555	COG1132	(ABC) transporter
FY145_18575	COG0483	inositol monophosphate 1-phosphatase activity
FY145_18605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY145_18610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY145_18615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY145_18620	COG0457	Tetratricopeptide repeat
FY145_18625	COG3750	Belongs to the UPF0335 family
FY145_18645	COG0469	pyruvate kinase activity
FY145_18650	COG3108	Peptidase M15
FY145_18655	COG2204	response regulator
FY145_18660	COG1164	Oligoendopeptidase f
FY145_18665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY145_18675	COG5310	Homospermidine synthase
FY145_18685	COG0737	Belongs to the 5'-nucleotidase family
FY145_18690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY145_18695	COG0330	HflC and HflK could
FY145_18720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY145_18725	COG2951	lytic endotransglycosylase activity
FY145_18740	COG2205	protein histidine kinase activity
FY145_18755	COG0067	glutamate synthase
FY145_18755	COG0069	glutamate synthase activity
FY145_18755	COG0070	glutamate synthase
FY145_18770	COG2205	protein histidine kinase activity
FY145_18775	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY145_18780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY145_18785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY145_18795	COG0252	asparaginase activity
FY145_18805	COG1027	Aspartate ammonia-lyase
FY145_18810	COG2186	Transcriptional regulator
FY145_18850	COG4176	ABC-type proline glycine betaine transport system permease component
FY145_18855	COG4175	Glycine betaine
FY145_18855	COG0517	IMP dehydrogenase activity
FY145_18860	COG2986	histidine ammonia-lyase
FY145_18865	COG1609	Transcriptional regulator
FY145_18885	COG1082	Xylose isomerase domain protein TIM barrel
FY145_18890	COG0673	inositol 2-dehydrogenase activity
FY145_18895	COG1082	Xylose isomerase domain protein TIM barrel
FY145_18920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY145_18965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_18975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_18980	COG0601	transmembrane transport
FY145_18985	COG0747	negative chemotaxis
FY145_18995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY145_19000	COG1454	alcohol dehydrogenase
FY145_19040	COG2308	Evidence 4 Homologs of previously reported genes of
FY145_19040	COG2307	Protein conserved in bacteria
FY145_19055	COG0488	(ABC) transporter
FY145_19060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY145_19065	COG2186	Transcriptional regulator
FY145_19080	COG1175	transmembrane transport
FY145_19085	COG0395	ABC-type sugar transport system, permease component
FY145_19095	COG3842	ATPase activity
FY145_19120	COG1304	FMN binding
FY145_19135	COG1063	alcohol dehydrogenase
FY145_19140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY145_19145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_19155	COG0765	amino acid transport
FY145_19160	COG0765	amino acid transport
FY145_19165	COG4221	oxidoreductase activity
FY145_19170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY145_19175	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_19180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY145_19195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY145_19210	COG0697	spore germination
FY145_19215	COG0697	spore germination
FY145_19220	COG0511	ligase activity, forming carbon-carbon bonds
FY145_19225	COG0439	Biotin carboxylase
FY145_19235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY145_19240	COG1984	allophanate hydrolase subunit 2
FY145_19245	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY145_19250	COG3842	ATPase activity
FY145_19260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY145_19270	COG0436	Aminotransferase
FY145_19285	COG0840	transmembrane signaling receptor activity
FY145_19290	COG1070	Carbohydrate kinase
FY145_19295	COG1830	Aldolase
FY145_19300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY145_19305	COG0667	Aldo Keto reductase
FY145_19315	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_19320	COG1129	ABC transporter
FY145_19325	COG1879	ABC-type sugar transport system periplasmic component
FY145_19370	COG0071	Belongs to the small heat shock protein (HSP20) family
FY145_19385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY145_19400	COG0395	ABC-type sugar transport system, permease component
FY145_19415	COG3842	ATPase activity
FY145_19430	COG1648	precorrin-2 dehydrogenase activity
FY145_19430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY145_19435	COG0243	molybdopterin cofactor binding
FY145_19445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY145_19450	COG1116	anion transmembrane transporter activity
FY145_19455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_19460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY145_19470	COG3707	response regulator
FY145_19475	COG1802	Transcriptional regulator
FY145_19480	COG1914	H( )-stimulated, divalent metal cation uptake system
FY145_19485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY145_19490	COG4336	lyase activity
FY145_19495	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY145_19500	COG4770	biotin carboxylase activity
FY145_19505	COG0366	Alpha amylase catalytic
FY145_19515	COG4771	TonB-dependent receptor
FY145_19520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY145_19540	COG1414	Transcriptional regulator
FY145_19545	COG1475	DNA binding
FY145_19550	COG1192	Involved in chromosome partitioning
FY145_19580	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY145_19590	COG2986	histidine ammonia-lyase
FY145_19595	COG1228	amidohydrolase
FY145_19600	COG0402	S-adenosylhomocysteine deaminase activity
FY145_19640	COG4172	Belongs to the ABC transporter superfamily
FY145_19645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_19650	COG0601	transmembrane transport
FY145_19655	COG4166	transmembrane transport
FY145_19660	COG0395	ABC-type sugar transport system, permease component
FY145_19680	COG1566	PFAM secretion protein HlyD family protein
FY145_19695	COG2207	Transcriptional regulator
FY145_19700	COG1309	transcriptional regulator
FY145_19705	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_19730	COG1846	Transcriptional regulator
FY145_19735	COG0583	DNA-binding transcription factor activity
FY145_19740	COG2828	Protein conserved in bacteria
FY145_19755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_19770	COG0840	transmembrane signaling receptor activity
FY145_19790	COG1215	transferase activity, transferring glycosyl groups
FY145_19820	COG0583	DNA-binding transcription factor activity
FY145_19825	COG0346	lactoylglutathione lyase activity
FY145_19840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY145_19860	COG0583	DNA-binding transcription factor activity
FY145_19865	COG0477	Major facilitator Superfamily
FY145_19875	COG2205	protein histidine kinase activity
FY145_19880	COG0745	RESPONSE REGULATOR receiver
FY145_19885	COG0671	phosphoesterase, PA-phosphatase related
FY145_19935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY145_19940	COG0156	8-amino-7-oxononanoate synthase activity
FY145_19945	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY145_19950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY145_19955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY145_19970	COG0010	Belongs to the arginase family
FY145_19980	COG0697	spore germination
FY145_19985	COG0673	inositol 2-dehydrogenase activity
FY145_20010	COG0477	Major facilitator Superfamily
FY145_20025	COG2194	sulfuric ester hydrolase activity
FY145_20035	COG0583	DNA-binding transcription factor activity
FY145_20040	COG4774	siderophore transport
FY145_20055	COG1120	ATPase activity
FY145_20065	COG3474	cytochrome
FY145_20070	COG2137	regulation of response to DNA damage stimulus
FY145_20075	COG3386	PFAM SMP-30 Gluconolaconase
FY145_20085	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_20090	COG1129	ABC transporter
FY145_20095	COG1879	ABC-type sugar transport system periplasmic component
FY145_20100	COG4585	Histidine kinase
FY145_20105	COG2197	response regulator
FY145_20115	COG2133	pyrroloquinoline quinone binding
FY145_20125	COG0500	methyltransferase
FY145_20130	COG0564	pseudouridine synthase activity
FY145_20145	COG4175	Glycine betaine
FY145_20145	COG3448	diguanylate cyclase activity
FY145_20150	COG4176	ABC-type proline glycine betaine transport system permease component
FY145_20165	COG4191	Histidine kinase
FY145_20165	COG0784	Response regulator, receiver
FY145_20170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY145_20175	COG0489	protein tyrosine kinase activity
FY145_20175	COG3206	protein involved in exopolysaccharide biosynthesis
FY145_20180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY145_20185	COG1215	transferase activity, transferring glycosyl groups
FY145_20190	COG1215	transferase activity, transferring glycosyl groups
FY145_20195	COG1215	transferase activity, transferring glycosyl groups
FY145_20200	COG0438	transferase activity, transferring glycosyl groups
FY145_20205	COG2273	Hydrolase Family 16
FY145_20210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY145_20215	COG2244	polysaccharide biosynthetic process
FY145_20220	COG0463	Glycosyl transferase, family 2
FY145_20225	COG2327	Polysaccharide pyruvyl transferase
FY145_20230	COG1215	transferase activity, transferring glycosyl groups
FY145_20250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY145_20255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_20270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY145_20270	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY145_20300	COG1523	belongs to the glycosyl hydrolase 13 family
FY145_20305	COG0033	Phosphoglucomutase
FY145_20310	COG0297	glycogen (starch) synthase activity
FY145_20315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY145_20320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY145_20325	COG0058	SHG alpha-glucan phosphorylase activity
FY145_20340	COG1794	racemase activity, acting on amino acids and derivatives
FY145_20345	COG1522	sequence-specific DNA binding
FY145_20355	COG2084	Dehydrogenase
FY145_20360	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_20365	COG1063	alcohol dehydrogenase
FY145_20375	COG4988	ABC transporter
FY145_20380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY145_20390	COG1294	oxidase, subunit
FY145_20420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY145_20425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY145_20455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY145_20460	COG0539	negative regulation of cytoplasmic translation
FY145_20490	COG4221	oxidoreductase activity
FY145_20500	COG0747	negative chemotaxis
FY145_20505	COG0601	transmembrane transport
FY145_20510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_20515	COG0444	Belongs to the ABC transporter superfamily
FY145_20520	COG4608	Belongs to the ABC transporter superfamily
FY145_20525	COG0246	Mannitol dehydrogenase
FY145_20540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_20585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY145_20590	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_20605	COG4993	Dehydrogenase
FY145_20610	COG3685	Protein conserved in bacteria
FY145_20640	COG0693	protein deglycase activity
FY145_20660	COG0189	ligase activity
FY145_20665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY145_20670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY145_20685	COG0435	Glutathione S-transferase
FY145_20690	COG0583	DNA-binding transcription factor activity
FY145_20695	COG1012	belongs to the aldehyde dehydrogenase family
FY145_20700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY145_20705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_20710	COG1116	anion transmembrane transporter activity
FY145_20720	COG1522	sequence-specific DNA binding
FY145_20735	COG0784	Response regulator, receiver
FY145_20755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY145_20770	COG0019	diaminopimelate decarboxylase activity
FY145_20785	COG0527	aspartate kinase activity
FY145_20795	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY145_20800	COG2890	protein-(glutamine-N5) methyltransferase activity
FY145_20810	COG0542	response to heat
FY145_20815	COG0739	heme binding
FY145_20815	COG0741	lytic transglycosylase activity
FY145_20815	COG1196	nuclear chromosome segregation
FY145_20860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY145_20870	COG1280	lysine exporter protein (LysE YggA)
FY145_20885	COG1309	transcriptional regulator
FY145_20890	COG4221	oxidoreductase activity
FY145_20895	COG1902	pentaerythritol trinitrate reductase activity
FY145_20900	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_20940	COG1278	Cold shock
FY145_20960	COG0753	catalase activity
FY145_20985	COG3920	Histidine kinase
FY145_20990	COG1280	lysine exporter protein (LysE YggA)
FY145_21010	COG0583	DNA-binding transcription factor activity
FY145_21045	COG0583	DNA-binding transcription factor activity
FY145_21055	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_21060	COG1846	Transcriptional regulator
FY145_21080	COG2186	Transcriptional regulator
FY145_21090	COG1126	abc transporter atp-binding protein
FY145_21100	COG0765	amino acid transport
FY145_21105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_21120	COG0436	Aminotransferase
FY145_21125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_21155	COG0405	Gamma-glutamyltransferase
FY145_21165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY145_21170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_21175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_21185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_21190	COG0747	negative chemotaxis
FY145_21195	COG0747	negative chemotaxis
FY145_21205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_21215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_21225	COG1129	ABC transporter
FY145_21230	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_21235	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_21260	COG0667	Aldo Keto reductase
FY145_21275	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_21280	COG1129	ABC transporter
FY145_21285	COG4213	ABC transporter substrate-binding protein
FY145_21305	COG4608	Belongs to the ABC transporter superfamily
FY145_21310	COG0444	Belongs to the ABC transporter superfamily
FY145_21315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_21320	COG0601	transmembrane transport
FY145_21325	COG0747	negative chemotaxis
FY145_21350	COG0765	amino acid transport
FY145_21355	COG4597	amino acid ABC transporter
FY145_21360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_21375	COG3177	Filamentation induced by cAMP protein fic
FY145_21400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_21430	COG3209	COG3209 Rhs family protein
FY145_21450	COG0745	RESPONSE REGULATOR receiver
FY145_21460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_21465	COG1136	(ABC) transporter
FY145_21465	COG0577	efflux transmembrane transporter activity
FY145_21475	COG1733	regulation of RNA biosynthetic process
FY145_21510	COG0534	Mate efflux family protein
FY145_21525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY145_21530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY145_21540	COG1566	PFAM secretion protein HlyD family protein
FY145_21550	COG0625	glutathione transferase activity
FY145_21555	COG4221	oxidoreductase activity
FY145_21565	COG2376	Dihydroxyacetone kinase
FY145_21570	COG1522	sequence-specific DNA binding
FY145_21590	COG0431	NADPH-dependent FMN reductase
FY145_21600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_21610	COG4172	Belongs to the ABC transporter superfamily
FY145_21615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_21635	COG0277	FAD linked oxidase domain protein
FY145_21655	COG0778	Nitroreductase
FY145_21685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY145_21710	COG2318	DinB family
FY145_21715	COG0583	DNA-binding transcription factor activity
FY145_21730	COG1335	isochorismatase
FY145_21755	COG3842	ATPase activity
FY145_21760	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_21765	COG1177	transmembrane transport
FY145_21770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY145_21780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY145_21795	COG1120	ATPase activity
FY145_21800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_21805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_21810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY145_21815	COG4774	siderophore transport
FY145_21815	COG1629	transport
FY145_21820	COG4702	Belongs to the UPF0303 family
FY145_21840	COG1024	Enoyl-CoA hydratase
FY145_21845	COG1012	belongs to the aldehyde dehydrogenase family
FY145_21850	COG1653	transport
FY145_21855	COG1175	transmembrane transport
FY145_21860	COG0395	ABC-type sugar transport system, permease component
FY145_21865	COG3842	ATPase activity
FY145_21895	COG3474	cytochrome
FY145_21900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY145_21905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY145_21910	COG1845	cytochrome c oxidase, subunit III
FY145_21935	COG0577	efflux transmembrane transporter activity
FY145_21935	COG1136	(ABC) transporter
FY145_21990	COG3842	ATPase activity
FY145_22000	COG1177	transmembrane transport
FY145_22005	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_22020	COG1940	carbohydrate kinase activity
FY145_22040	COG1069	ribulokinase activity
FY145_22045	COG1349	DNA-binding transcription factor activity
FY145_22050	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_22075	COG0395	ABC-type sugar transport system, permease component
FY145_22085	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_22100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY145_22110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY145_22120	COG0477	Major facilitator Superfamily
FY145_22170	COG1733	regulation of RNA biosynthetic process
FY145_22205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY145_22210	COG3938	Belongs to the proline racemase family
FY145_22215	COG4176	ABC-type proline glycine betaine transport system permease component
FY145_22225	COG4175	Glycine betaine
FY145_22225	COG3448	diguanylate cyclase activity
FY145_22235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_22240	COG1012	belongs to the aldehyde dehydrogenase family
FY145_22245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_22255	COG0047	phosphoribosylformylglycinamidine synthase activity
FY145_22260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_22270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY145_22270	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY145_22280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY145_22300	COG1309	transcriptional regulator
FY145_22315	COG1136	(ABC) transporter
FY145_22330	COG1063	alcohol dehydrogenase
FY145_22340	COG1879	ABC-type sugar transport system periplasmic component
FY145_22350	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_22370	COG0477	Major facilitator Superfamily
FY145_22500	COG5001	Diguanylate cyclase
FY145_22500	COG3300	MHYT domain
FY145_22525	COG1253	flavin adenine dinucleotide binding
FY145_22540	COG3842	ATPase activity
FY145_22545	COG0395	ABC-type sugar transport system, permease component
FY145_22550	COG1175	transmembrane transport
FY145_22555	COG1653	transport
FY145_22565	COG0673	inositol 2-dehydrogenase activity
FY145_22570	COG1609	Transcriptional regulator
FY145_22585	COG0583	DNA-binding transcription factor activity
FY145_22595	COG1879	ABC-type sugar transport system periplasmic component
FY145_22600	COG1129	ABC transporter
FY145_22605	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_22610	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_22615	COG1609	Transcriptional regulator
FY145_22625	COG0673	inositol 2-dehydrogenase activity
FY145_22685	COG0714	Associated with various cellular activities
FY145_22690	COG3256	nitric oxide reductase
FY145_22720	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY145_22725	COG3189	MarR family transcriptional regulator
FY145_22735	COG0826	peptidase U32
FY145_22770	COG4459	periplasmic nitrate reductase
FY145_22785	COG0243	molybdopterin cofactor binding
FY145_22795	COG3005	denitrification pathway
FY145_22810	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_22815	COG1535	isochorismatase
FY145_22815	COG3433	isochorismatase activity
FY145_22820	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY145_22825	COG1169	isochorismate synthase
FY145_22835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY145_22835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY145_22840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY145_22850	COG2375	cellular response to nickel ion
FY145_22860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_22865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_22875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_22885	COG4774	siderophore transport
FY145_22885	COG1629	transport
FY145_22890	COG1960	acyl-CoA dehydrogenase activity
FY145_22895	COG0583	DNA-binding transcription factor activity
FY145_22900	COG1609	Transcriptional regulator
FY145_22910	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_22920	COG3842	ATPase activity
FY145_22930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY145_22935	COG0583	DNA-binding transcription factor activity
FY145_22940	COG2814	Major facilitator Superfamily
FY145_22945	COG1473	amidohydrolase
FY145_22960	COG0747	negative chemotaxis
FY145_22965	COG0601	transmembrane transport
FY145_22970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_22975	COG0444	Belongs to the ABC transporter superfamily
FY145_22980	COG4608	Belongs to the ABC transporter superfamily
FY145_22985	COG0583	DNA-binding transcription factor activity
FY145_22990	COG0747	negative chemotaxis
FY145_23000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_23005	COG0154	amidase activity
FY145_23010	COG0693	protein deglycase activity
FY145_23020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_23025	COG0601	transmembrane transport
FY145_23035	COG1473	amidohydrolase
FY145_23040	COG4172	Belongs to the ABC transporter superfamily
FY145_23045	COG2390	Transcriptional regulator
FY145_23055	COG1175	transmembrane transport
FY145_23060	COG0395	ABC-type sugar transport system, permease component
FY145_23110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY145_23130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY145_23135	COG1414	Transcriptional regulator
FY145_23140	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_23150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY145_23155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY145_23160	COG1121	(ABC) transporter
FY145_23165	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY145_23175	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY145_23180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY145_23185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY145_23190	COG0471	metal ion transport
FY145_23190	COG3273	potassium ion transport
FY145_23195	COG1253	flavin adenine dinucleotide binding
FY145_23200	COG1309	transcriptional regulator
FY145_23220	COG1609	Transcriptional regulator
FY145_23225	COG1070	Carbohydrate kinase
FY145_23230	COG2115	Belongs to the xylose isomerase family
FY145_23240	COG0778	Nitroreductase
FY145_23245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY145_23250	COG2011	ABC-type metal ion transport system permease component
FY145_23260	COG3300	MHYT domain
FY145_23260	COG5001	Diguanylate cyclase
FY145_23265	COG1054	Belongs to the UPF0176 family
FY145_23275	COG2954	triphosphatase activity
FY145_23280	COG0800	Aldolase
FY145_23300	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY145_23340	COG0523	cobalamin synthesis protein
FY145_23350	COG1846	Transcriptional regulator
FY145_23355	COG1609	Transcriptional regulator
FY145_23360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY145_23370	COG3718	enzyme involved in inositol metabolism
FY145_23380	COG3962	Belongs to the TPP enzyme family
FY145_23385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_23400	COG0411	ABC transporter
FY145_23415	COG0683	leucine binding
FY145_23430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_23440	COG0747	negative chemotaxis
FY145_23445	COG4172	Belongs to the ABC transporter superfamily
FY145_23470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY145_23475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY145_23480	COG1126	abc transporter atp-binding protein
FY145_23485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_23490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_23495	COG0765	amino acid transport
FY145_23500	COG0765	amino acid transport
FY145_23505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY145_23510	COG3485	protocatechuate 3,4-dioxygenase
FY145_23515	COG3485	protocatechuate 3,4-dioxygenase
FY145_23520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY145_23530	COG0583	DNA-binding transcription factor activity
FY145_23545	COG1414	Transcriptional regulator
FY145_23555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY145_23560	COG0183	Belongs to the thiolase family
FY145_23565	COG1609	Transcriptional regulator
FY145_23580	COG1082	Xylose isomerase domain protein TIM barrel
FY145_23585	COG0673	inositol 2-dehydrogenase activity
FY145_23595	COG1609	Transcriptional regulator
FY145_23600	COG0395	ABC-type sugar transport system, permease component
FY145_23605	COG1175	transmembrane transport
FY145_23610	COG3842	ATPase activity
FY145_23620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY145_23640	COG2814	Major facilitator Superfamily
FY145_23645	COG4774	siderophore transport
FY145_23650	COG3712	iron ion homeostasis
FY145_23660	COG1940	carbohydrate kinase activity
FY145_23665	COG0584	glycerophosphoryl diester phosphodiesterase
FY145_23670	COG0300	oxidoreductase activity
FY145_23685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY145_23705	COG0667	Aldo Keto reductase
FY145_23710	COG0583	DNA-binding transcription factor activity
FY145_23720	COG1132	(ABC) transporter
FY145_23735	COG1442	glycosyl transferase family 8
FY145_23735	COG1216	Glycosyl transferase, family 2
FY145_23740	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY145_23750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY145_23770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY145_23775	COG3754	Rhamnan synthesis protein F
FY145_23790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY145_23795	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY145_23800	COG1088	dTDP-glucose 4,6-dehydratase activity
FY145_23805	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY145_23810	COG0210	DNA helicase
FY145_23820	COG1609	Transcriptional regulator
FY145_23825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY145_23825	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY145_23840	COG0395	ABC-type sugar transport system, permease component
FY145_23845	COG3842	ATPase activity
FY145_23855	COG0444	Belongs to the ABC transporter superfamily
FY145_23860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_23865	COG0601	transmembrane transport
FY145_23870	COG2186	Transcriptional regulator
FY145_23890	COG5001	Diguanylate cyclase
FY145_23890	COG3300	MHYT domain
FY145_23895	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_23905	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY145_23915	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY145_23920	COG0306	phosphate transporter
FY145_23925	COG1392	Phosphate transport regulator
FY145_23940	COG1566	PFAM secretion protein HlyD family protein
FY145_23945	COG0745	RESPONSE REGULATOR receiver
FY145_23950	COG2205	protein histidine kinase activity
FY145_23965	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY145_23975	COG4774	siderophore transport
FY145_23985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_23990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_23995	COG1120	ATPase activity
FY145_24000	COG0583	DNA-binding transcription factor activity
FY145_24010	COG3119	arylsulfatase activity
FY145_24015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY145_24020	COG3842	ATPase activity
FY145_24025	COG0165	Argininosuccinate lyase
FY145_24030	COG0395	ABC-type sugar transport system, permease component
FY145_24035	COG1175	transmembrane transport
FY145_24040	COG2182	Extracellular solute-binding protein
FY145_24045	COG1940	carbohydrate kinase activity
FY145_24070	COG1486	melibiose metabolic process
FY145_24075	COG0747	negative chemotaxis
FY145_24080	COG0601	transmembrane transport
FY145_24085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_24090	COG4172	Belongs to the ABC transporter superfamily
FY145_24095	COG1486	melibiose metabolic process
FY145_24100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY145_24105	COG0842	Transport permease protein
FY145_24105	COG1129	ABC transporter
FY145_24110	COG0842	Transport permease protein
FY145_24125	COG0784	Response regulator, receiver
FY145_24130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY145_24140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_24145	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY145_24160	COG0765	amino acid transport
FY145_24170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_24180	COG3938	Belongs to the proline racemase family
FY145_24195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_24200	COG0765	amino acid transport
FY145_24205	COG0765	amino acid transport
FY145_24215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY145_24230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY145_24250	COG3383	formate dehydrogenase (NAD+) activity
FY145_24260	COG2223	nitrite transmembrane transporter activity
FY145_24265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY145_24275	COG2186	Transcriptional regulator
FY145_24280	COG0747	negative chemotaxis
FY145_24285	COG0601	transmembrane transport
FY145_24290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_24295	COG4172	Belongs to the ABC transporter superfamily
FY145_24300	COG4948	Mandelate Racemase Muconate Lactonizing
FY145_24310	COG2186	Transcriptional regulator
FY145_24315	COG0747	negative chemotaxis
FY145_24320	COG0601	transmembrane transport
FY145_24325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_24330	COG0405	Gamma-glutamyltransferase
FY145_24340	COG0483	inositol monophosphate 1-phosphatase activity
FY145_24350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY145_24355	COG0395	ABC-type sugar transport system, permease component
FY145_24375	COG3237	CsbD-like
FY145_24385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY145_24390	COG3181	Tripartite tricarboxylate transporter family receptor
FY145_24395	COG5265	(ABC) transporter
FY145_24400	COG0488	(ABC) transporter
FY145_24425	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY145_24430	COG0110	maltose O-acetyltransferase activity
FY145_24440	COG1063	alcohol dehydrogenase
FY145_24445	COG3284	Transcriptional regulator
FY145_24465	COG1129	ABC transporter
FY145_24470	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_24475	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_24485	COG0572	uridine kinase
FY145_24490	COG1082	Xylose isomerase domain protein TIM barrel
FY145_24515	COG4178	(ABC) transporter
FY145_24555	COG0640	Transcriptional regulator
FY145_24580	COG1192	Involved in chromosome partitioning
FY145_24585	COG1475	DNA binding
FY145_24590	COG0640	Transcriptional regulator
FY145_24605	COG1126	abc transporter atp-binding protein
FY145_24610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_24615	COG1609	Transcriptional regulator
FY145_24650	COG3239	Fatty acid desaturase
FY145_24660	COG1278	Cold shock
FY145_24740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY145_24740	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY145_24775	COG4191	Histidine kinase
FY145_24780	COG1132	(ABC) transporter
FY145_24790	COG0640	Transcriptional regulator
FY145_24820	COG4977	sequence-specific DNA binding
FY145_24825	COG2211	Major facilitator Superfamily
FY145_24830	COG2807	transmembrane transport
FY145_24835	COG1846	Transcriptional regulator
FY145_24850	COG2814	Major facilitator Superfamily
FY145_24880	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY145_24895	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY145_24900	COG0583	DNA-binding transcription factor activity
FY145_24915	COG0071	Belongs to the small heat shock protein (HSP20) family
FY145_24960	COG3838	Conjugal transfer protein Trbc
FY145_24965	COG3702	type iv secretory pathway
FY145_24970	COG3451	type IV secretory pathway VirB4
FY145_24985	COG3704	protein secretion by the type IV secretion system
FY145_24995	COG3736	Type IV secretory pathway, component VirB8
FY145_25000	COG3504	Conjugal transfer protein
FY145_25005	COG2948	multi-organism process
FY145_25010	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY145_25110	COG3831	ATPase activity
FY145_25125	COG3505	Type IV secretory pathway VirD4
FY145_25150	COG0583	DNA-binding transcription factor activity
FY145_25190	COG0745	RESPONSE REGULATOR receiver
FY145_25230	COG3842	ATPase activity
FY145_25235	COG4208	sulfate ABC transporter
FY145_25240	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_25260	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY145_25265	COG1942	4-Oxalocrotonate Tautomerase
FY145_25275	COG3971	2-oxopent-4-enoate hydratase activity
FY145_25285	COG1414	Transcriptional regulator
FY145_25295	COG1137	ATPase activity
FY145_25310	COG4177	L-phenylalanine transmembrane transporter activity
FY145_25330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY145_25335	COG1175	transmembrane transport
FY145_25340	COG0395	ABC-type sugar transport system, permease component
FY145_25350	COG0366	Alpha amylase catalytic
FY145_25355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY145_25360	COG1082	Xylose isomerase domain protein TIM barrel
FY145_25365	COG3842	ATPase activity
FY145_25375	COG1940	carbohydrate kinase activity
FY145_25380	COG0395	ABC-type sugar transport system, permease component
FY145_25390	COG2182	Extracellular solute-binding protein
FY145_25395	COG0673	inositol 2-dehydrogenase activity
FY145_25425	COG1126	abc transporter atp-binding protein
FY145_25430	COG0765	amino acid transport
FY145_25435	COG0765	amino acid transport
FY145_25445	COG4608	Belongs to the ABC transporter superfamily
FY145_25455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_25470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY145_25475	COG0583	DNA-binding transcription factor activity
FY145_25480	COG2423	ornithine cyclodeaminase activity
FY145_25490	COG1957	nucleoside hydrolase
FY145_25510	COG1335	isochorismatase
FY145_25515	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_25550	COG3547	Transposase (IS116 IS110 IS902 family)
FY145_25555	COG0251	oxidation-reduction process
FY145_25560	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY145_25615	COG4215	(ABC) transporter
FY145_25625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_25640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_25650	COG0747	negative chemotaxis
FY145_25670	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY145_25705	COG0477	Major facilitator Superfamily
FY145_25715	COG0395	ABC-type sugar transport system, permease component
FY145_25720	COG1175	transmembrane transport
FY145_25725	COG3842	ATPase activity
FY145_25735	COG4948	Mandelate Racemase Muconate Lactonizing
FY145_25745	COG1414	Transcriptional regulator
FY145_25750	COG0583	DNA-binding transcription factor activity
FY145_25785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY145_25795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY145_25820	COG1129	ABC transporter
FY145_25840	COG2272	Belongs to the type-B carboxylesterase lipase family
FY145_25850	COG2271	Major facilitator Superfamily
FY145_25855	COG0583	DNA-binding transcription factor activity
FY145_25880	COG1129	ABC transporter
FY145_25890	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_25895	COG1940	carbohydrate kinase activity
FY145_25920	COG2084	Dehydrogenase
FY145_25925	COG3622	Belongs to the hyi family
FY145_25930	COG3386	PFAM SMP-30 Gluconolaconase
FY145_25940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY145_25950	COG1012	belongs to the aldehyde dehydrogenase family
FY145_25990	COG1846	Transcriptional regulator
FY145_26010	COG3706	GGDEF domain
FY145_26025	COG0477	Major facilitator Superfamily
FY145_26030	COG1012	belongs to the aldehyde dehydrogenase family
FY145_26040	COG1024	Enoyl-CoA hydratase
FY145_26045	COG1960	acyl-CoA dehydrogenase activity
FY145_26055	COG1063	alcohol dehydrogenase
FY145_26070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY145_26075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY145_26090	COG3971	2-oxopent-4-enoate hydratase activity
FY145_26095	COG3485	protocatechuate 3,4-dioxygenase
FY145_26100	COG1802	Transcriptional regulator
FY145_26115	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_26160	COG2207	Transcriptional regulator
FY145_26240	COG1695	Transcriptional regulator
FY145_26250	COG0583	DNA-binding transcription factor activity
FY145_26255	COG1335	isochorismatase
FY145_26265	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_26270	COG0583	DNA-binding transcription factor activity
FY145_26275	COG1902	pentaerythritol trinitrate reductase activity
FY145_26280	COG0583	DNA-binding transcription factor activity
FY145_26325	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_26330	COG1335	isochorismatase
FY145_26340	COG1309	transcriptional regulator
FY145_26345	COG4604	ABC transporter, ATP-binding protein
FY145_26350	COG4605	iron ion homeostasis
FY145_26355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY145_26365	COG2132	Multicopper oxidase
FY145_26370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY145_26375	COG4771	TonB-dependent receptor
FY145_26410	COG1695	Transcriptional regulator
FY145_26445	COG2132	Multicopper oxidase
FY145_26480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY145_26500	COG1192	Involved in chromosome partitioning
FY145_26505	COG1475	DNA binding
FY145_26510	COG0640	Transcriptional regulator
FY145_26515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY145_26545	COG2211	Major facilitator Superfamily
FY145_26595	COG1051	belongs to the nudix hydrolase family
FY145_26635	COG1475	DNA binding
FY145_26660	COG2824	Alkylphosphonate utilization operon protein PhnA
FY145_26680	COG1280	lysine exporter protein (LysE YggA)
FY145_26695	COG5489	Protein of unknown function (DUF736)
FY145_26755	COG1879	ABC-type sugar transport system periplasmic component
FY145_26760	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_26780	COG1280	lysine exporter protein (LysE YggA)
FY145_26865	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY145_26880	COG0747	negative chemotaxis
FY145_26885	COG0444	Belongs to the ABC transporter superfamily
FY145_26900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_26905	COG0584	glycerophosphoryl diester phosphodiesterase
FY145_26910	COG0483	inositol monophosphate 1-phosphatase activity
FY145_26975	COG3161	chorismate lyase activity
FY145_27125	COG3436	PFAM IS66 Orf2 family protein
FY145_27205	COG2222	sugar isomerase
FY145_27215	COG0006	proline dipeptidase activity
FY145_27235	COG1177	transmembrane transport
FY145_27240	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY145_27245	COG3842	ATPase activity
FY145_27275	COG3842	ATPase activity
FY145_27280	COG0006	proline dipeptidase activity
FY145_27300	COG0300	oxidoreductase activity
FY145_27305	COG0129	dihydroxy-acid dehydratase activity
FY145_27310	COG0667	Aldo Keto reductase
FY145_27320	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_27330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_27335	COG0601	transmembrane transport
FY145_27340	COG4172	Belongs to the ABC transporter superfamily
FY145_27350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY145_27385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_27420	COG3701	Conjugal transfer protein
FY145_27425	COG3846	protein secretion by the type IV secretion system
FY145_27435	COG5314	conjugation
FY145_27440	COG3451	type IV secretory pathway VirB4
FY145_27455	COG4962	Type ii secretion system protein e
FY145_27465	COG1192	Involved in chromosome partitioning
FY145_27470	COG1475	DNA binding
FY145_27475	COG0640	Transcriptional regulator
FY145_27480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY145_27525	COG0583	DNA-binding transcription factor activity
FY145_27535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY145_27540	COG1116	anion transmembrane transporter activity
FY145_27545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY145_27555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_27560	COG1028	Short-chain dehydrogenase reductase Sdr
FY145_27590	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY145_27595	COG1129	ABC transporter
FY145_27620	COG4172	Belongs to the ABC transporter superfamily
FY145_27625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_27630	COG0601	transmembrane transport
FY145_27640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_27645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_27650	COG0583	DNA-binding transcription factor activity
FY145_27660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY145_27675	COG1132	(ABC) transporter
FY145_27680	COG4172	Belongs to the ABC transporter superfamily
FY145_27685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_27705	COG1082	Xylose isomerase domain protein TIM barrel
FY145_27710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY145_27715	COG0019	diaminopimelate decarboxylase activity
FY145_27725	COG1475	DNA binding
FY145_27735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY145_27825	COG1475	DNA binding
FY145_27850	COG2824	Alkylphosphonate utilization operon protein PhnA
FY145_27875	COG5489	Protein of unknown function (DUF736)
FY145_27935	COG0583	DNA-binding transcription factor activity
FY145_27940	COG1126	abc transporter atp-binding protein
FY145_27945	COG0765	amino acid transport
FY145_27950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY145_27955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_27960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY145_28020	COG0584	glycerophosphoryl diester phosphodiesterase
FY145_28030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_28045	COG0444	Belongs to the ABC transporter superfamily
FY145_28070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY145_28075	COG0601	transmembrane transport
FY145_28090	COG0444	Belongs to the ABC transporter superfamily
FY145_28095	COG0747	negative chemotaxis
FY145_28105	COG2390	Transcriptional regulator
FY145_28150	COG0145	ligase activity
FY145_28160	COG0583	DNA-binding transcription factor activity
FY145_28205	COG3701	Conjugal transfer protein
FY145_28210	COG3846	protein secretion by the type IV secretion system
FY145_28225	COG3451	type IV secretory pathway VirB4
FY145_28240	COG4962	Type ii secretion system protein e