locus-tag	class	description
FY147_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY147_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY147_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY147_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY147_00025	COG1420	regulation of RNA biosynthetic process
FY147_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY147_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY147_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY147_00050	COG1137	ATPase activity
FY147_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY147_00065	COG0616	signal peptide processing
FY147_00070	COG0776	regulation of translation
FY147_00080	COG0116	Belongs to the methyltransferase superfamily
FY147_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY147_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY147_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY147_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY147_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY147_00115	COG0728	peptidoglycan biosynthetic process
FY147_00125	COG0180	Tryptophanyl-tRNA synthetase
FY147_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY147_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY147_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY147_00165	COG1702	phosphate starvation-inducible protein PhoH
FY147_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY147_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY147_00185	COG1396	sequence-specific DNA binding
FY147_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY147_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY147_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_00210	COG0242	peptide deformylase activity
FY147_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY147_00220	COG0101	tRNA pseudouridine synthase activity
FY147_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY147_00235	COG2171	N-acyltransferase activity
FY147_00245	COG0840	transmembrane signaling receptor activity
FY147_00250	COG1957	nucleoside hydrolase
FY147_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY147_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY147_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY147_00295	COG0706	membrane insertase activity
FY147_00300	COG0594	ribonuclease P activity
FY147_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY147_00310	COG0840	transmembrane signaling receptor activity
FY147_00325	COG2226	methyltransferase
FY147_00330	COG3842	ATPase activity
FY147_00335	COG1175	transmembrane transport
FY147_00340	COG0395	ABC-type sugar transport system, permease component
FY147_00355	COG0427	acetyl-CoA hydrolase
FY147_00365	COG3938	Belongs to the proline racemase family
FY147_00370	COG0418	dihydroorotase activity
FY147_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY147_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY147_00400	COG0166	Belongs to the GPI family
FY147_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY147_00410	COG3842	ATPase activity
FY147_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY147_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY147_00425	COG4774	siderophore transport
FY147_00470	COG2326	polyphosphate kinase activity
FY147_00475	COG5002	protein histidine kinase activity
FY147_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY147_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY147_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY147_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY147_00505	COG0745	RESPONSE REGULATOR receiver
FY147_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY147_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY147_00530	COG2967	ApaG domain
FY147_00545	COG0717	Belongs to the dCTP deaminase family
FY147_00555	COG0582	viral genome integration into host DNA
FY147_00580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY147_00630	COG1396	sequence-specific DNA binding
FY147_00645	COG1132	(ABC) transporter
FY147_00680	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY147_00685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY147_00735	COG0167	dihydroorotate dehydrogenase activity
FY147_00750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY147_00770	COG1959	2 iron, 2 sulfur cluster binding
FY147_00775	COG1201	RNA secondary structure unwinding
FY147_00805	COG1960	acyl-CoA dehydrogenase activity
FY147_00810	COG0183	Belongs to the thiolase family
FY147_00815	COG1024	Enoyl-CoA hydratase
FY147_00815	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY147_00835	COG1320	monovalent cation:proton antiporter activity
FY147_00840	COG2212	antiporter activity
FY147_00845	COG1863	multisubunit Na H antiporter MnhE subunit
FY147_00850	COG0651	ATP synthesis coupled electron transport
FY147_00855	COG1006	Multisubunit Na H antiporter MnhC subunit
FY147_00860	COG2111	Na H antiporter
FY147_00860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY147_00870	COG0840	transmembrane signaling receptor activity
FY147_00880	COG0745	RESPONSE REGULATOR receiver
FY147_00885	COG2198	Histidine kinase
FY147_00885	COG0643	Histidine kinase
FY147_00890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY147_00895	COG2201	protein-glutamate methylesterase activity
FY147_00900	COG0745	RESPONSE REGULATOR receiver
FY147_00905	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY147_00915	COG1766	The M ring may be actively involved in energy transduction
FY147_00920	COG2771	luxR family
FY147_00930	COG0840	transmembrane signaling receptor activity
FY147_00930	COG2972	Histidine kinase
FY147_00935	COG2198	Histidine kinase
FY147_00935	COG2205	protein histidine kinase activity
FY147_00935	COG0784	Response regulator, receiver
FY147_00940	COG1970	mechanosensitive ion channel activity
FY147_00945	COG0436	Aminotransferase
FY147_00960	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY147_00965	COG0424	maF-like protein
FY147_00970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY147_00980	COG5328	Belongs to the UPF0262 family
FY147_00985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY147_00995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY147_01015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY147_01025	COG1338	Plays a role in the flagellum-specific transport system
FY147_01035	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY147_01045	COG1706	bacterial-type flagellum-dependent cell motility
FY147_01050	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY147_01055	COG4786	Flagellar basal body rod
FY147_01060	COG1677	Flagellar hook-basal body complex protein FliE
FY147_01065	COG1558	bacterial-type flagellum-dependent cell motility
FY147_01070	COG1815	bacterial-type flagellum-dependent cell motility
FY147_01080	COG1157	protein secretion by the type III secretion system
FY147_01085	COG4786	Flagellar basal body rod
FY147_01095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY147_01100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY147_01105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY147_01110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY147_01115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY147_01140	COG1360	Flagellar Motor Protein
FY147_01165	COG1749	Flagellar hook protein flgE
FY147_01185	COG5443	negative regulation of bacterial-type flagellum assembly
FY147_01190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY147_01200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY147_01240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY147_01245	COG1609	Transcriptional regulator
FY147_01250	COG1653	transport
FY147_01255	COG1175	transmembrane transport
FY147_01260	COG0395	ABC-type sugar transport system, permease component
FY147_01265	COG0366	Alpha amylase catalytic
FY147_01270	COG3842	ATPase activity
FY147_01285	COG0129	dihydroxy-acid dehydratase activity
FY147_01290	COG0363	glucosamine-6-phosphate deaminase activity
FY147_01295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY147_01305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_01315	COG2081	HI0933 family
FY147_01335	COG2224	Isocitrate lyase
FY147_01350	COG3842	ATPase activity
FY147_01355	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_01360	COG1177	transmembrane transport
FY147_01370	COG2205	protein histidine kinase activity
FY147_01380	COG0248	Ppx GppA phosphatase
FY147_01385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY147_01390	COG0477	Major facilitator Superfamily
FY147_01420	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY147_01425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY147_01435	COG0142	geranyltranstransferase activity
FY147_01460	COG0752	glycyl-tRNA synthetase alpha subunit
FY147_01470	COG1704	LemA family
FY147_01475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY147_01485	COG0751	glycine-tRNA ligase activity
FY147_01490	COG1683	Conserved Protein
FY147_01495	COG0840	transmembrane signaling receptor activity
FY147_01505	COG0151	Belongs to the GarS family
FY147_01510	COG2183	response to ionizing radiation
FY147_01515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY147_01525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY147_01540	COG0583	DNA-binding transcription factor activity
FY147_01560	COG0306	phosphate transporter
FY147_01570	COG0561	phosphatase activity
FY147_01575	COG0438	transferase activity, transferring glycosyl groups
FY147_01580	COG2186	Transcriptional regulator
FY147_01595	COG0583	DNA-binding transcription factor activity
FY147_01600	COG0277	FAD linked oxidase domain protein
FY147_01605	COG0277	FAD linked oxidase domain protein
FY147_01610	COG0247	lactate metabolic process
FY147_01620	COG1376	ErfK ybiS ycfS ynhG family protein
FY147_01625	COG2818	Glycosylase
FY147_01635	COG2855	membrane
FY147_01640	COG0583	DNA-binding transcription factor activity
FY147_01670	COG0124	histidyl-tRNA synthetase
FY147_01680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY147_01685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY147_01690	COG2259	Doxx family
FY147_01700	COG0459	protein refolding
FY147_01705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY147_01715	COG0196	riboflavin kinase activity
FY147_01720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY147_01730	COG0590	tRNA wobble adenosine to inosine editing
FY147_01735	COG1187	pseudouridine synthase activity
FY147_01740	COG0742	ribosomal rna small subunit methyltransferase
FY147_01745	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY147_01755	COG0312	modulator of DNA gyrase
FY147_01760	COG0483	inositol monophosphate 1-phosphatase activity
FY147_01770	COG1519	Transferase
FY147_01780	COG1663	tetraacyldisaccharide 4'-kinase activity
FY147_01790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY147_01795	COG0745	RESPONSE REGULATOR receiver
FY147_01800	COG5001	Diguanylate cyclase
FY147_01800	COG3300	MHYT domain
FY147_01805	COG3386	PFAM SMP-30 Gluconolaconase
FY147_01810	COG0800	Aldolase
FY147_01815	COG3734	2-keto-3-deoxy-galactonokinase
FY147_01820	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_01825	COG1414	Transcriptional regulator
FY147_01830	COG2197	response regulator
FY147_01845	COG0598	Magnesium transport protein CorA
FY147_01850	COG3158	transport of potassium into the cell
FY147_01865	COG0356	it plays a direct role in the translocation of protons across the membrane
FY147_01875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY147_01880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY147_01895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY147_01915	COG0009	L-threonylcarbamoyladenylate synthase
FY147_01925	COG4638	Rieske (2fe-2S)
FY147_01950	COG1960	acyl-CoA dehydrogenase activity
FY147_01965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY147_01970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY147_01975	COG0840	transmembrane signaling receptor activity
FY147_01985	COG1522	sequence-specific DNA binding
FY147_02010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY147_02015	COG1741	Belongs to the pirin family
FY147_02020	COG1722	exodeoxyribonuclease VII activity
FY147_02025	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY147_02030	COG1268	BioY protein
FY147_02035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY147_02040	COG1122	ATPase activity
FY147_02045	COG3214	Protein conserved in bacteria
FY147_02050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY147_02050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY147_02055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY147_02070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY147_02085	COG0259	pyridoxamine-phosphate oxidase activity
FY147_02115	COG0312	modulator of DNA gyrase
FY147_02130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY147_02135	COG0109	protoheme IX farnesyltransferase activity
FY147_02140	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY147_02155	COG3346	SURF1 family
FY147_02160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY147_02165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY147_02170	COG0328	RNA-DNA hybrid ribonuclease activity
FY147_02180	COG0678	peroxiredoxin activity
FY147_02180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY147_02190	COG1678	Uncharacterized ACR, COG1678
FY147_02195	COG3237	CsbD-like
FY147_02205	COG5001	Diguanylate cyclase
FY147_02205	COG3300	MHYT domain
FY147_02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY147_02215	COG0612	Peptidase, M16
FY147_02240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY147_02245	COG1802	Transcriptional regulator
FY147_02260	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY147_02265	COG3609	addiction module antidote protein, CC2985 family
FY147_02270	COG3668	Plasmid stabilization system
FY147_02280	COG1194	a g-specific adenine glycosylase
FY147_02295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY147_02300	COG1196	nuclear chromosome segregation
FY147_02305	COG2514	catechol 2,3-dioxygenase activity
FY147_02310	COG0574	Belongs to the PEP-utilizing enzyme family
FY147_02310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY147_02325	COG1823	symporter activity
FY147_02355	COG0579	oxidoreductase
FY147_02375	COG2895	sulfate adenylyltransferase (ATP) activity
FY147_02380	COG0175	sulfate reduction
FY147_02385	COG0175	sulfate reduction
FY147_02390	COG1959	2 iron, 2 sulfur cluster binding
FY147_02395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY147_02400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY147_02405	COG4208	sulfate ABC transporter
FY147_02410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY147_02420	COG2203	Gaf domain
FY147_02420	COG2199	diguanylate cyclase activity
FY147_02420	COG2200	EAL domain
FY147_02430	COG1309	transcriptional regulator
FY147_02435	COG1012	belongs to the aldehyde dehydrogenase family
FY147_02440	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY147_02470	COG0625	glutathione transferase activity
FY147_02480	COG0477	Major facilitator Superfamily
FY147_02490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY147_02490	COG1793	dna ligase
FY147_02510	COG1376	ErfK ybiS ycfS ynhG family protein
FY147_02515	COG1376	ErfK ybiS ycfS ynhG family protein
FY147_02520	COG1846	Transcriptional regulator
FY147_02525	COG1764	response to oxidative stress
FY147_02540	COG0488	(ABC) transporter
FY147_02575	COG4221	oxidoreductase activity
FY147_02590	COG0433	COG0433 Predicted ATPase
FY147_02600	COG1733	regulation of RNA biosynthetic process
FY147_02605	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY147_02620	COG0656	L-ascorbic acid biosynthetic process
FY147_02625	COG3781	membrane
FY147_02630	COG2378	regulation of single-species biofilm formation
FY147_02640	COG4106	trans-aconitate 2-methyltransferase activity
FY147_02645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY147_02650	COG0840	transmembrane signaling receptor activity
FY147_02655	COG0583	DNA-binding transcription factor activity
FY147_02670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY147_02690	COG3909	cytochrome
FY147_02695	COG2010	Cytochrome c
FY147_02725	COG0789	Transcriptional regulator
FY147_02750	COG0517	IMP dehydrogenase activity
FY147_02750	COG4175	Glycine betaine
FY147_02755	COG4176	ABC-type proline glycine betaine transport system permease component
FY147_02775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_02785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY147_02785	COG2169	Transcriptional regulator
FY147_02795	COG2514	catechol 2,3-dioxygenase activity
FY147_02815	COG1272	protein, Hemolysin III
FY147_02825	COG1280	lysine exporter protein (LysE YggA)
FY147_02830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY147_02835	COG2111	Na H antiporter
FY147_02835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY147_02840	COG2111	Na H antiporter
FY147_02845	COG1006	Multisubunit Na H antiporter MnhC subunit
FY147_02850	COG0651	ATP synthesis coupled electron transport
FY147_02855	COG1863	multisubunit Na H antiporter MnhE subunit
FY147_02860	COG2212	antiporter activity
FY147_02865	COG1320	monovalent cation:proton antiporter activity
FY147_02870	COG4957	zinc ion binding
FY147_02885	COG2166	iron-sulfur cluster assembly
FY147_02895	COG2205	protein histidine kinase activity
FY147_02940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY147_02945	COG2983	Belongs to the UPF0260 family
FY147_02955	COG3041	Addiction module toxin RelE StbE family
FY147_02960	COG3077	Addiction module antitoxin, RelB DinJ family
FY147_03000	COG2814	Major facilitator Superfamily
FY147_03005	COG1621	beta-fructofuranosidase activity
FY147_03010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY147_03060	COG4695	Portal protein
FY147_03165	COG4235	cytochrome complex assembly
FY147_03170	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY147_03175	COG1138	Cytochrome C-type biogenesis protein
FY147_03180	COG3088	subunit of a heme lyase
FY147_03185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY147_03190	COG0745	RESPONSE REGULATOR receiver
FY147_03200	COG3011	Protein conserved in bacteria
FY147_03205	COG3713	MltA-interacting MipA family protein
FY147_03210	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY147_03215	COG2202	Pas domain
FY147_03215	COG2205	protein histidine kinase activity
FY147_03225	COG0308	aminopeptidase N
FY147_03230	COG0697	spore germination
FY147_03245	COG0443	Heat shock 70 kDa protein
FY147_03280	COG0604	alcohol dehydrogenase
FY147_03285	COG1733	regulation of RNA biosynthetic process
FY147_03290	COG1968	undecaprenyl-diphosphatase activity
FY147_03295	COG2239	Acts as a magnesium transporter
FY147_03300	COG2814	Major facilitator Superfamily
FY147_03325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY147_03350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY147_03390	COG0741	lytic transglycosylase activity
FY147_03395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_03400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY147_03405	COG0840	transmembrane signaling receptor activity
FY147_03415	COG1758	RNA polymerase activity
FY147_03435	COG0736	holo-[acyl-carrier-protein] synthase activity
FY147_03440	COG0681	Belongs to the peptidase S26 family
FY147_03445	COG0571	ribonuclease III activity
FY147_03450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY147_03460	COG0784	Response regulator, receiver
FY147_03465	COG1381	Involved in DNA repair and RecF pathway recombination
FY147_03475	COG2226	methyltransferase
FY147_03485	COG1418	mRNA catabolic process
FY147_03495	COG0346	lactoylglutathione lyase activity
FY147_03510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_03515	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY147_03520	COG0668	transmembrane transport
FY147_03530	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY147_03560	COG1742	UPF0060 membrane protein
FY147_03575	COG1183	phosphatidylcholine synthase activity
FY147_03580	COG0688	phosphatidylethanolamine metabolic process
FY147_03585	COG5265	(ABC) transporter
FY147_03625	COG2852	Protein conserved in bacteria
FY147_03630	COG0215	cysteine-tRNA ligase activity
FY147_03635	COG4221	oxidoreductase activity
FY147_03640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY147_03645	COG1286	toxin biosynthetic process
FY147_03665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY147_03675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY147_03685	COG0305	Participates in initiation and elongation during chromosome replication
FY147_03705	COG0359	binds to the 23S rRNA
FY147_03715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY147_03720	COG0360	Binds together with S18 to 16S ribosomal RNA
FY147_03730	COG0667	Aldo Keto reductase
FY147_03735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY147_03745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY147_03750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY147_03760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY147_03765	COG1561	YicC-like family, N-terminal region
FY147_03770	COG0194	GDP metabolic process
FY147_03785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY147_03790	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY147_03800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY147_03815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY147_03835	COG2203	Gaf domain
FY147_03835	COG3706	GGDEF domain
FY147_03835	COG4251	negative regulation of phosphorylation
FY147_03835	COG5001	Diguanylate cyclase
FY147_03840	COG3300	MHYT domain
FY147_03840	COG5001	Diguanylate cyclase
FY147_03845	COG4191	Histidine kinase
FY147_03850	COG4566	intracellular signal transduction
FY147_03860	COG0488	(ABC) transporter
FY147_03865	COG3706	GGDEF domain
FY147_03875	COG0105	UTP biosynthetic process
FY147_03895	COG0314	molybdopterin synthase activity
FY147_03905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY147_03910	COG0322	excinuclease ABC activity
FY147_03915	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_03940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY147_03945	COG0243	molybdopterin cofactor binding
FY147_03970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY147_03975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY147_03980	COG2226	methyltransferase
FY147_03985	COG0628	permease
FY147_03995	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY147_04000	COG0248	Ppx GppA phosphatase
FY147_04025	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY147_04035	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY147_04040	COG0477	Major facilitator Superfamily
FY147_04045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY147_04055	COG0840	transmembrane signaling receptor activity
FY147_04060	COG0659	secondary active sulfate transmembrane transporter activity
FY147_04070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY147_04075	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY147_04085	COG0113	porphobilinogen synthase activity
FY147_04105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY147_04110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY147_04115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY147_04115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY147_04125	COG1280	lysine exporter protein (LysE YggA)
FY147_04130	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY147_04135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY147_04140	COG2814	Major facilitator Superfamily
FY147_04145	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY147_04165	COG0416	fatty acid biosynthetic process
FY147_04170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY147_04175	COG0776	regulation of translation
FY147_04210	COG0601	transmembrane transport
FY147_04215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_04220	COG0444	Belongs to the ABC transporter superfamily
FY147_04230	COG0747	negative chemotaxis
FY147_04240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY147_04245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY147_04260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY147_04265	COG0583	DNA-binding transcription factor activity
FY147_04270	COG0737	Belongs to the 5'-nucleotidase family
FY147_04290	COG2897	thiosulfate sulfurtransferase activity
FY147_04305	COG0415	Belongs to the DNA photolyase family
FY147_04315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY147_04345	COG3932	Exopolysaccharide synthesis, ExoD
FY147_04350	COG1238	metal cluster binding
FY147_04425	COG1612	heme a metabolic process
FY147_04435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY147_04440	COG0010	Belongs to the arginase family
FY147_04445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY147_04450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY147_04460	COG1832	CoA-binding protein
FY147_04485	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_04490	COG2124	cytochrome p450
FY147_04495	COG2199	diguanylate cyclase activity
FY147_04500	COG0740	serine-type endopeptidase activity
FY147_04505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY147_04510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY147_04520	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY147_04545	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY147_04550	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY147_04555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY147_04565	COG0649	NAD binding
FY147_04575	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY147_04580	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY147_04590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY147_04595	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY147_04605	COG0713	ATP synthesis coupled electron transport
FY147_04620	COG1007	ATP synthesis coupled electron transport
FY147_04625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY147_04625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY147_04640	COG0442	prolyl-tRNA aminoacylation
FY147_04650	COG1136	(ABC) transporter
FY147_04665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY147_04685	COG0784	Response regulator, receiver
FY147_04695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY147_04700	COG0477	Major facilitator Superfamily
FY147_04715	COG0557	exoribonuclease II activity
FY147_04720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY147_04730	COG0758	DNA mediated transformation
FY147_04735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY147_04745	COG0540	Belongs to the ATCase OTCase family
FY147_04760	COG1960	acyl-CoA dehydrogenase activity
FY147_04765	COG0456	acetyltransferase
FY147_04785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY147_04790	COG2824	Alkylphosphonate utilization operon protein PhnA
FY147_04795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY147_04800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY147_04805	COG0154	amidase activity
FY147_04810	COG0456	acetyltransferase
FY147_04815	COG3811	Belongs to the UPF0386 family
FY147_04830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY147_04840	COG0456	acetyltransferase
FY147_04860	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY147_04865	COG0439	Biotin carboxylase
FY147_04870	COG0511	ligase activity, forming carbon-carbon bonds
FY147_04875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY147_04885	COG0436	Aminotransferase
FY147_04905	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_04910	COG1530	ribonuclease E activity
FY147_04920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY147_04940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY147_04945	COG0384	phenazine biosynthesis protein PhzF
FY147_04965	COG0633	Ferredoxin
FY147_04980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY147_04985	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY147_04995	COG3768	UPF0283 membrane protein
FY147_05000	COG3106	COG3106 Predicted ATPase
FY147_05030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY147_05065	COG0537	adenosine 5'-monophosphoramidase activity
FY147_05090	COG0052	Belongs to the universal ribosomal protein uS2 family
FY147_05095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY147_05100	COG0528	UMP kinase activity
FY147_05105	COG0233	cytoplasmic translational termination
FY147_05110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY147_05120	COG0750	zinc metalloprotease
FY147_05125	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY147_05130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY147_05135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY147_05140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY147_05145	COG3494	Protein of unknown function (DUF1009)
FY147_05150	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY147_05155	COG2186	Transcriptional regulator
FY147_05165	COG0765	amino acid transport
FY147_05170	COG0765	amino acid transport
FY147_05180	COG0372	Belongs to the citrate synthase family
FY147_05195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY147_05205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY147_05210	COG0148	phosphopyruvate hydratase activity
FY147_05220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY147_05225	COG0022	dehydrogenase e1 component
FY147_05225	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY147_05230	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY147_05240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY147_05250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY147_05255	COG0697	spore germination
FY147_05270	COG2867	negative regulation of translational initiation
FY147_05275	COG1058	Belongs to the CinA family
FY147_05275	COG1546	Belongs to the CinA family
FY147_05280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY147_05280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY147_05290	COG3852	Histidine kinase
FY147_05295	COG2204	response regulator
FY147_05300	COG5000	phosphorelay sensor kinase activity
FY147_05305	COG2204	response regulator
FY147_05310	COG0569	domain protein
FY147_05315	COG1923	regulation of RNA biosynthetic process
FY147_05320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY147_05325	COG3956	TIGRFAM MazG family protein
FY147_05335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY147_05335	COG1648	precorrin-2 dehydrogenase activity
FY147_05375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY147_05375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY147_05380	COG0509	glycine decarboxylation via glycine cleavage system
FY147_05385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY147_05410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY147_05415	COG0564	pseudouridine synthase activity
FY147_05435	COG0251	oxidation-reduction process
FY147_05440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY147_05450	COG1671	Belongs to the UPF0178 family
FY147_05465	COG0450	alkyl hydroperoxide reductase
FY147_05470	COG0625	glutathione transferase activity
FY147_05480	COG2801	Transposase and inactivated derivatives
FY147_05485	COG0431	NADPH-dependent FMN reductase
FY147_05495	COG0798	PFAM Bile acid sodium symporter
FY147_05500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY147_05515	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY147_05515	COG0321	lipoyl(octanoyl) transferase activity
FY147_05520	COG0084	hydrolase, TatD family'
FY147_05525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY147_05535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY147_05590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY147_05595	COG2095	MarC family integral membrane protein
FY147_05600	COG0617	tRNA 3'-terminal CCA addition
FY147_05600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY147_05600	COG0517	IMP dehydrogenase activity
FY147_05610	COG0629	single-stranded DNA binding
FY147_05615	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY147_05625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY147_05630	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY147_05645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY147_05650	COG1121	(ABC) transporter
FY147_05670	COG0667	Aldo Keto reductase
FY147_05680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY147_05765	COG2239	Acts as a magnesium transporter
FY147_05770	COG0243	molybdopterin cofactor binding
FY147_05780	COG0242	peptide deformylase activity
FY147_05790	COG2205	protein histidine kinase activity
FY147_05790	COG2202	Pas domain
FY147_05800	COG0321	lipoyl(octanoyl) transferase activity
FY147_05805	COG1064	alcohol dehydrogenase
FY147_05835	COG1862	Preprotein translocase
FY147_05855	COG2124	cytochrome p450
FY147_05870	COG0596	Alpha beta hydrolase
FY147_05885	COG0626	cystathionine gamma-synthase activity
FY147_05890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_05895	COG4597	amino acid ABC transporter
FY147_05900	COG0765	amino acid transport
FY147_05905	COG1126	abc transporter atp-binding protein
FY147_05920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY147_05935	COG0436	Aminotransferase
FY147_05965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY147_05975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY147_05980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY147_05985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY147_06000	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY147_06005	COG1489	DNA binding
FY147_06010	COG0024	Methionine aminopeptidase
FY147_06015	COG2003	Belongs to the UPF0758 family
FY147_06030	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY147_06055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY147_06060	COG0546	phosphoglycolate phosphatase activity
FY147_06070	COG0114	fumarate hydratase activity
FY147_06080	COG0504	CTP synthase activity
FY147_06090	COG0149	triose-phosphate isomerase activity
FY147_06100	COG0187	DNA topoisomerase II activity
FY147_06110	COG0740	serine-type endopeptidase activity
FY147_06120	COG0640	Transcriptional regulator
FY147_06125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY147_06130	COG0745	RESPONSE REGULATOR receiver
FY147_06145	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY147_06145	COG3264	Mechanosensitive ion channel
FY147_06205	COG1127	ABC transporter
FY147_06210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY147_06215	COG4948	Mandelate Racemase Muconate Lactonizing
FY147_06225	COG0281	malic enzyme
FY147_06225	COG0280	phosphate acetyltransferase
FY147_06235	COG0778	Nitroreductase
FY147_06240	COG0823	Involved in the tonB-independent uptake of proteins
FY147_06255	COG1368	sulfuric ester hydrolase activity
FY147_06275	COG3265	gluconokinase activity
FY147_06280	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY147_06300	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY147_06320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY147_06335	COG0318	PFAM AMP-dependent synthetase and ligase
FY147_06345	COG0512	Glutamine amidotransferase of anthranilate synthase
FY147_06345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY147_06350	COG0343	queuine tRNA-ribosyltransferase activity
FY147_06355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY147_06370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY147_06385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY147_06390	COG0134	indole-3-glycerol-phosphate synthase activity
FY147_06395	COG0315	cyclic pyranopterin monophosphate synthase activity
FY147_06400	COG0303	'Molybdopterin
FY147_06405	COG3706	GGDEF domain
FY147_06415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY147_06415	COG0475	glutathione-regulated potassium exporter activity
FY147_06425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY147_06435	COG2814	Major facilitator Superfamily
FY147_06440	COG0746	molybdenum cofactor guanylyltransferase activity
FY147_06445	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY147_06450	COG0739	heme binding
FY147_06455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY147_06460	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY147_06465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY147_06470	COG0805	protein transport
FY147_06475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY147_06480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY147_06485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY147_06490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY147_06495	COG1472	Belongs to the glycosyl hydrolase 3 family
FY147_06505	COG0018	arginyl-trna synthetase
FY147_06510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY147_06535	COG0525	valine-tRNA ligase activity
FY147_06545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY147_06790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY147_06800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FY147_07005	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY147_07010	COG1058	Belongs to the CinA family
FY147_07010	COG1546	Belongs to the CinA family
FY147_07015	COG0589	response to stress
FY147_07020	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY147_07030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY147_07090	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY147_07110	COG2815	serine threonine protein kinase
FY147_07110	COG0515	serine threonine protein kinase
FY147_07130	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_07135	COG0583	DNA-binding transcription factor activity
FY147_07140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY147_07205	COG0640	Transcriptional regulator
FY147_07210	COG1914	H( )-stimulated, divalent metal cation uptake system
FY147_07220	COG1132	(ABC) transporter
FY147_07225	COG0628	permease
FY147_07260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY147_07270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY147_07280	COG0302	gtp cyclohydrolase
FY147_07285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY147_07290	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY147_07300	COG0517	IMP dehydrogenase activity
FY147_07300	COG0516	GMP reductase activity
FY147_07335	COG1760	l-serine dehydratase
FY147_07375	COG0583	DNA-binding transcription factor activity
FY147_07390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY147_07390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY147_07400	COG0347	Belongs to the P(II) protein family
FY147_07405	COG0174	glutamine synthetase
FY147_07435	COG0697	spore germination
FY147_07445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY147_07455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY147_07485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY147_07490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY147_07495	COG2186	Transcriptional regulator
FY147_07505	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY147_07510	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY147_07515	COG3845	ABC transporter
FY147_07520	COG1183	phosphatidylcholine synthase activity
FY147_07525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY147_07530	COG0679	Auxin Efflux Carrier
FY147_07535	COG0785	Cytochrome C biogenesis protein
FY147_07555	COG1278	Cold shock
FY147_07605	COG0577	efflux transmembrane transporter activity
FY147_07605	COG1136	(ABC) transporter
FY147_07610	COG0577	efflux transmembrane transporter activity
FY147_07610	COG1136	(ABC) transporter
FY147_07635	COG2151	metal-sulfur cluster biosynthetic enzyme
FY147_07640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY147_07645	COG0719	Fe-S assembly protein
FY147_07650	COG0396	ATPase activity
FY147_07655	COG0719	Fe-S assembly protein
FY147_07660	COG1104	cysteine desulfurase activity
FY147_07665	COG2945	thiolester hydrolase activity
FY147_07670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY147_07675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY147_07685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY147_07690	COG2833	Protein of unknown function (DUF455)
FY147_07695	COG0739	heme binding
FY147_07700	COG0513	Belongs to the DEAD box helicase family
FY147_07725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY147_07735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY147_07740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY147_07745	COG0047	phosphoribosylformylglycinamidine synthase activity
FY147_07760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY147_07765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY147_07785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY147_07790	COG2814	Major facilitator Superfamily
FY147_07930	COG4373	Mu-like prophage FluMu protein gp28
FY147_07935	COG4383	Mu-like prophage protein gp29
FY147_07960	COG4397	Mu-like prophage major head subunit gpT
FY147_07980	COG4387	Mu-like prophage protein GP36
FY147_08035	COG3299	homolog of phage Mu protein gp47
FY147_08060	COG0483	inositol monophosphate 1-phosphatase activity
FY147_08065	COG0483	inositol monophosphate 1-phosphatase activity
FY147_08070	COG0037	tRNA processing
FY147_08075	COG2066	Belongs to the glutaminase family
FY147_08080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY147_08085	COG0861	Integral membrane protein TerC family
FY147_08100	COG1280	lysine exporter protein (LysE YggA)
FY147_08110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY147_08115	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY147_08125	COG0538	isocitrate dehydrogenase activity
FY147_08135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY147_08140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY147_08145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_08150	COG2313	pseudouridylate synthase activity
FY147_08160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_08165	COG4215	(ABC) transporter
FY147_08175	COG5425	PFAM Usg family protein
FY147_08185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY147_08190	COG1522	sequence-specific DNA binding
FY147_08195	COG1573	uracil-dna glycosylase
FY147_08205	COG2205	protein histidine kinase activity
FY147_08205	COG2202	Pas domain
FY147_08215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY147_08220	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY147_08235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY147_08240	COG0842	Transport permease protein
FY147_08245	COG1131	(ABC) transporter
FY147_08250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY147_08250	COG0730	response to heat
FY147_08270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY147_08275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY147_08295	COG0129	dihydroxy-acid dehydratase activity
FY147_08300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY147_08305	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY147_08315	COG3739	integral membrane protein
FY147_08325	COG0203	ribosomal protein L17
FY147_08330	COG0202	RNA polymerase activity
FY147_08335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY147_08340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY147_08345	COG0563	adenylate kinase activity
FY147_08350	COG0201	protein transport
FY147_08355	COG0200	Binds to the 23S rRNA
FY147_08360	COG1841	ribosomal large subunit assembly
FY147_08365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY147_08370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY147_08375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY147_08380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY147_08385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY147_08390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY147_08395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY147_08400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY147_08405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY147_08410	COG0255	Belongs to the universal ribosomal protein uL29 family
FY147_08415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY147_08420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY147_08425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY147_08430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY147_08435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY147_08440	COG0089	rRNA binding
FY147_08445	COG0088	Forms part of the polypeptide exit tunnel
FY147_08450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY147_08455	COG0051	transcription antitermination factor activity, RNA binding
FY147_08460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY147_08465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY147_08470	COG0049	tRNA binding
FY147_08475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY147_08495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY147_08500	COG0085	RNA polymerase activity
FY147_08505	COG0222	ribosome binding
FY147_08510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY147_08515	COG0081	regulation of translation
FY147_08520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY147_08530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY147_08540	COG1086	Polysaccharide biosynthesis protein
FY147_08545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY147_08550	COG0861	Integral membrane protein TerC family
FY147_08555	COG3895	Periplasmic Protein
FY147_08575	COG1132	(ABC) transporter
FY147_08580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY147_08600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY147_08635	COG0784	Response regulator, receiver
FY147_08635	COG2198	Histidine kinase
FY147_08635	COG2205	protein histidine kinase activity
FY147_08635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_08640	COG0784	Response regulator, receiver
FY147_08645	COG2202	Pas domain
FY147_08645	COG3920	Histidine kinase
FY147_08650	COG0784	Response regulator, receiver
FY147_08655	COG4251	negative regulation of phosphorylation
FY147_08670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY147_08675	COG1607	acyl-coa hydrolase
FY147_08695	COG2910	NAD(P)H-binding
FY147_08700	COG1733	regulation of RNA biosynthetic process
FY147_08715	COG0556	nucleotide-excision repair
FY147_08725	COG2382	esterase
FY147_08745	COG0484	heat shock protein binding
FY147_08765	COG3706	GGDEF domain
FY147_08785	COG1840	ABC-type Fe3 transport system, periplasmic component
FY147_08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY147_08805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY147_08815	COG2207	Transcriptional regulator
FY147_08820	COG1064	alcohol dehydrogenase
FY147_08825	COG1252	NADH dehydrogenase
FY147_08830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY147_08840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY147_08875	COG0656	L-ascorbic acid biosynthetic process
FY147_08890	COG0440	acetolactate synthase activity
FY147_08895	COG0028	Belongs to the TPP enzyme family
FY147_08910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY147_08915	COG0560	Phosphoserine phosphatase
FY147_08915	COG3830	Belongs to the UPF0237 family
FY147_08935	COG0330	HflC and HflK could
FY147_08940	COG0330	HflC and HflK could
FY147_08950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY147_08985	COG0277	FAD linked oxidase domain protein
FY147_08990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY147_09030	COG1335	isochorismatase
FY147_09055	COG2264	protein methyltransferase activity
FY147_09060	COG1999	signal sequence binding
FY147_09070	COG0835	chemotaxis
FY147_09080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY147_09085	COG0583	DNA-binding transcription factor activity
FY147_09095	COG1247	-acetyltransferase
FY147_09105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY147_09110	COG0497	DNA recombination
FY147_09115	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY147_09125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY147_09130	COG0849	cell division
FY147_09135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY147_09140	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY147_09145	COG0477	Major facilitator Superfamily
FY147_09150	COG5001	Diguanylate cyclase
FY147_09155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY147_09160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY147_09165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY147_09175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY147_09180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY147_09190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY147_09205	COG0275	rRNA processing
FY147_09210	COG2001	Belongs to the MraZ family
FY147_09235	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY147_09265	COG4106	trans-aconitate 2-methyltransferase activity
FY147_09285	COG2226	methyltransferase
FY147_09295	COG2267	carboxylic ester hydrolase activity
FY147_09300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY147_09315	COG0251	oxidation-reduction process
FY147_09330	COG1376	ErfK ybiS ycfS ynhG family protein
FY147_09335	COG2814	Major facilitator Superfamily
FY147_09365	COG1012	belongs to the aldehyde dehydrogenase family
FY147_09370	COG0174	glutamine synthetase
FY147_09375	COG0531	amino acid
FY147_09385	COG1737	Transcriptional regulator
FY147_09390	COG2182	Extracellular solute-binding protein
FY147_09405	COG3842	ATPase activity
FY147_09470	COG2968	Membrane
FY147_09480	COG0432	Pfam Uncharacterised protein family UPF0047
FY147_09495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY147_09500	COG0358	DNA primase activity
FY147_09520	COG0505	Belongs to the CarA family
FY147_09525	COG0534	Mate efflux family protein
FY147_09540	COG2321	neutral zinc metallopeptidase
FY147_09555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY147_09565	COG3706	GGDEF domain
FY147_09580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY147_09590	COG1522	sequence-specific DNA binding
FY147_09595	COG0492	ferredoxin-NADP+ reductase activity
FY147_09600	COG0583	DNA-binding transcription factor activity
FY147_09610	COG1902	pentaerythritol trinitrate reductase activity
FY147_09635	COG0387	Pfam Sodium calcium exchanger
FY147_09640	COG0436	Aminotransferase
FY147_09645	COG2199	diguanylate cyclase activity
FY147_09645	COG2200	EAL domain
FY147_09660	COG1278	Cold shock
FY147_09665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY147_09675	COG1846	Transcriptional regulator
FY147_09680	COG0745	RESPONSE REGULATOR receiver
FY147_09690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY147_09710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY147_09720	COG1496	oxidoreductase activity
FY147_09735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY147_09745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY147_09760	COG0840	transmembrane signaling receptor activity
FY147_09765	COG1012	belongs to the aldehyde dehydrogenase family
FY147_09770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY147_09775	COG3300	MHYT domain
FY147_09775	COG5001	Diguanylate cyclase
FY147_09780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY147_09785	COG5001	Diguanylate cyclase
FY147_09795	COG0193	aminoacyl-tRNA hydrolase activity
FY147_09805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY147_09830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY147_09840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY147_09840	COG2857	Cytochrome c1
FY147_09860	COG1132	(ABC) transporter
FY147_09865	COG1132	(ABC) transporter
FY147_09875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY147_09890	COG0408	coproporphyrinogen oxidase activity
FY147_09905	COG0617	tRNA 3'-terminal CCA addition
FY147_09920	COG0714	Associated with various cellular activities
FY147_09940	COG0454	-acetyltransferase
FY147_09955	COG0477	Major facilitator Superfamily
FY147_09965	COG0435	Glutathione S-transferase
FY147_09970	COG0494	nUDIX hydrolase
FY147_09980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY147_09985	COG3135	benzoate transporter
FY147_10010	COG0740	serine-type endopeptidase activity
FY147_10025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY147_10030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY147_10055	COG4175	Glycine betaine
FY147_10075	COG1435	thymidine kinase activity
FY147_10100	COG1629	transport
FY147_10100	COG4771	TonB-dependent receptor
FY147_10110	COG0512	Glutamine amidotransferase of anthranilate synthase
FY147_10110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY147_10125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY147_10135	COG0366	Alpha amylase catalytic
FY147_10140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_10160	COG1160	GTP binding
FY147_10180	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY147_10190	COG0024	Methionine aminopeptidase
FY147_10200	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_10220	COG0583	DNA-binding transcription factor activity
FY147_10235	COG0402	S-adenosylhomocysteine deaminase activity
FY147_10255	COG1309	transcriptional regulator
FY147_10260	COG1686	Belongs to the peptidase S11 family
FY147_10270	COG2351	hydroxyisourate hydrolase activity
FY147_10275	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY147_10290	COG3195	allantoin biosynthetic process
FY147_10290	COG3648	Uricase
FY147_10300	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY147_10310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_10310	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY147_10320	COG0513	Belongs to the DEAD box helicase family
FY147_10330	COG2259	Doxx family
FY147_10335	COG1376	ErfK ybiS ycfS ynhG family protein
FY147_10345	COG2308	Evidence 4 Homologs of previously reported genes of
FY147_10355	COG1305	Transglutaminase-like
FY147_10380	COG4214	carbohydrate transport
FY147_10390	COG4213	ABC transporter substrate-binding protein
FY147_10455	COG2948	multi-organism process
FY147_10465	COG3701	Conjugal transfer protein
FY147_10470	COG3846	protein secretion by the type IV secretion system
FY147_10485	COG3451	type IV secretory pathway VirB4
FY147_10495	COG3838	Conjugal transfer protein Trbc
FY147_10500	COG4962	Type ii secretion system protein e
FY147_10505	COG0583	DNA-binding transcription factor activity
FY147_10525	COG4172	Belongs to the ABC transporter superfamily
FY147_10535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_10550	COG0251	oxidation-reduction process
FY147_10555	COG1609	Transcriptional regulator
FY147_10590	COG0739	heme binding
FY147_10590	COG0741	lytic transglycosylase activity
FY147_10590	COG1196	nuclear chromosome segregation
FY147_10600	COG4959	Type IV secretory pathway protease TraF
FY147_10650	COG5489	Protein of unknown function (DUF736)
FY147_10690	COG4372	Transposase
FY147_10695	COG3436	PFAM IS66 Orf2 family protein
FY147_10700	COG2963	transposase activity
FY147_10735	COG2972	Histidine kinase
FY147_10735	COG0840	transmembrane signaling receptor activity
FY147_10750	COG0646	methionine synthase
FY147_10750	COG1410	methionine synthase
FY147_10795	COG1215	transferase activity, transferring glycosyl groups
FY147_10825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY147_10840	COG2346	COG2346, Truncated hemoglobins
FY147_10860	COG1309	transcriptional regulator
FY147_10875	COG0494	nUDIX hydrolase
FY147_10885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_10890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_10920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY147_10925	COG0830	nickel cation binding
FY147_10930	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY147_10945	COG0804	urea catabolic process
FY147_10950	COG1442	glycosyl transferase family 8
FY147_10955	COG3755	Protein conserved in bacteria
FY147_10965	COG0832	Belongs to the urease beta subunit family
FY147_10970	COG3813	Protein conserved in bacteria
FY147_10975	COG0831	urea catabolic process
FY147_10980	COG0829	nickel cation binding
FY147_11005	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY147_11020	COG0174	glutamine synthetase
FY147_11025	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_11030	COG2198	Histidine kinase
FY147_11030	COG5002	protein histidine kinase activity
FY147_11030	COG0784	Response regulator, receiver
FY147_11045	COG0726	polysaccharide deacetylase
FY147_11080	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY147_11155	COG0564	pseudouridine synthase activity
FY147_11165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY147_11175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY147_11200	COG0346	lactoylglutathione lyase activity
FY147_11210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY147_11220	COG2832	Protein of unknown function (DUF454)
FY147_11225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY147_11230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_11235	COG4558	Periplasmic binding protein
FY147_11245	COG3721	Heme iron utilization protein
FY147_11260	COG3655	Transcriptional regulator
FY147_11285	COG2205	protein histidine kinase activity
FY147_11330	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_11335	COG4605	iron ion homeostasis
FY147_11340	COG4604	ABC transporter, ATP-binding protein
FY147_11345	COG0783	Belongs to the Dps family
FY147_11360	COG0840	transmembrane signaling receptor activity
FY147_11360	COG2972	Histidine kinase
FY147_11365	COG0656	L-ascorbic acid biosynthetic process
FY147_11370	COG2814	Major facilitator Superfamily
FY147_11380	COG0583	DNA-binding transcription factor activity
FY147_11385	COG0657	acetylesterase activity
FY147_11390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_11410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY147_11415	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY147_11420	COG0288	reversible hydration of carbon dioxide
FY147_11430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY147_11450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY147_11455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY147_11460	COG0778	Nitroreductase
FY147_11465	COG2267	carboxylic ester hydrolase activity
FY147_11470	COG0251	oxidation-reduction process
FY147_11475	COG1335	isochorismatase
FY147_11480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_11490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_11505	COG1175	transmembrane transport
FY147_11510	COG0395	ABC-type sugar transport system, permease component
FY147_11515	COG3842	ATPase activity
FY147_11520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_11530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY147_11545	COG4608	Belongs to the ABC transporter superfamily
FY147_11550	COG0444	Belongs to the ABC transporter superfamily
FY147_11555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_11560	COG0601	transmembrane transport
FY147_11615	COG2159	amidohydrolase
FY147_11620	COG1960	acyl-CoA dehydrogenase activity
FY147_11650	COG0745	RESPONSE REGULATOR receiver
FY147_11660	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY147_11660	COG1902	pentaerythritol trinitrate reductase activity
FY147_11665	COG3842	ATPase activity
FY147_11675	COG1840	ABC-type Fe3 transport system, periplasmic component
FY147_11680	COG1840	ABC-type Fe3 transport system, periplasmic component
FY147_11685	COG0745	RESPONSE REGULATOR receiver
FY147_11695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY147_11700	COG0583	DNA-binding transcription factor activity
FY147_11705	COG1278	Cold shock
FY147_11740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY147_11745	COG1309	transcriptional regulator
FY147_11750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_11755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY147_11765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY147_11770	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY147_11790	COG0583	DNA-binding transcription factor activity
FY147_11795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_11800	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY147_11805	COG4149	molybdate abc transporter
FY147_11810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY147_11825	COG2022	thiamine diphosphate biosynthetic process
FY147_11840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY147_11850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY147_11860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY147_11880	COG1132	(ABC) transporter
FY147_11885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY147_11930	COG4166	transmembrane transport
FY147_11935	COG0601	transmembrane transport
FY147_11940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_11955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY147_11960	COG3142	Participates in the control of copper homeostasis
FY147_11965	COG2814	Major facilitator Superfamily
FY147_11980	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_11985	COG1737	Transcriptional regulator
FY147_11995	COG3842	ATPase activity
FY147_12005	COG0395	ABC-type sugar transport system, permease component
FY147_12020	COG2188	Transcriptional regulator
FY147_12025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY147_12030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY147_12035	COG1940	carbohydrate kinase activity
FY147_12045	COG0671	phosphoesterase, PA-phosphatase related
FY147_12050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY147_12055	COG0156	8-amino-7-oxononanoate synthase activity
FY147_12065	COG0729	surface antigen
FY147_12075	COG0835	chemotaxis
FY147_12085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY147_12090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY147_12095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY147_12100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY147_12105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY147_12110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY147_12125	COG4974	Belongs to the 'phage' integrase family
FY147_12150	COG1280	lysine exporter protein (LysE YggA)
FY147_12160	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY147_12165	COG0567	Dehydrogenase, E1 component
FY147_12170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY147_12175	COG0045	succinate-CoA ligase (ADP-forming) activity
FY147_12180	COG0039	L-malate dehydrogenase activity
FY147_12185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY147_12220	COG2264	protein methyltransferase activity
FY147_12235	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY147_12240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY147_12245	COG0181	hydroxymethylbilane synthase activity
FY147_12285	COG1872	DUF167
FY147_12290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY147_12300	COG1217	gtp-binding protein TYPA
FY147_12305	COG0339	signal peptide processing
FY147_12310	COG1846	Transcriptional regulator
FY147_12320	COG0137	argininosuccinate synthase activity
FY147_12330	COG1280	lysine exporter protein (LysE YggA)
FY147_12335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY147_12340	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY147_12350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY147_12365	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY147_12370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY147_12375	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY147_12385	COG4181	ATPase activity
FY147_12395	COG0670	Belongs to the BI1 family
FY147_12410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY147_12415	COG4133	protoheme IX ABC transporter activity
FY147_12420	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY147_12425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY147_12450	COG2917	probably involved in intracellular septation
FY147_12455	COG0552	protein localization to endoplasmic reticulum
FY147_12460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY147_12465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY147_12475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY147_12480	COG0287	Prephenate dehydrogenase
FY147_12480	COG1605	Chorismate mutase
FY147_12485	COG0228	four-way junction DNA binding
FY147_12490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY147_12495	COG0336	Belongs to the RNA methyltransferase TrmD family
FY147_12505	COG0335	large ribosomal subunit rRNA binding
FY147_12510	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY147_12515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_12530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY147_12550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY147_12570	COG0488	(ABC) transporter
FY147_12580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY147_12590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY147_12595	COG0142	geranyltranstransferase activity
FY147_12600	COG2885	chlorophyll binding
FY147_12605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY147_12610	COG2223	nitrite transmembrane transporter activity
FY147_12615	COG1349	DNA-binding transcription factor activity
FY147_12620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY147_12625	COG2197	response regulator
FY147_12630	COG1132	(ABC) transporter
FY147_12640	COG3459	Glycosyltransferase 36 associated
FY147_12645	COG1473	amidohydrolase
FY147_12650	COG0579	oxidoreductase
FY147_12660	COG0129	dihydroxy-acid dehydratase activity
FY147_12665	COG2084	Dehydrogenase
FY147_12670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY147_12675	COG0277	FAD linked oxidase domain protein
FY147_12680	COG2186	Transcriptional regulator
FY147_12690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY147_12695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY147_12700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY147_12705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY147_12715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY147_12720	COG0495	leucyl-tRNA aminoacylation
FY147_12735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY147_12740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY147_12755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY147_12760	COG1946	Acyl-CoA thioesterase
FY147_12765	COG0347	Belongs to the P(II) protein family
FY147_12770	COG0004	ammonium transporteR
FY147_12775	COG1674	ftsk spoiiie
FY147_12780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY147_12795	COG0745	RESPONSE REGULATOR receiver
FY147_12805	COG1329	Transcriptional regulator
FY147_12815	COG2270	Major facilitator Superfamily
FY147_12830	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_12845	COG0494	nUDIX hydrolase
FY147_12850	COG2861	carbohydrate metabolic process
FY147_12855	COG0793	Belongs to the peptidase S41A family
FY147_12865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY147_12870	COG0799	negative regulation of ribosome biogenesis
FY147_12875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY147_12880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY147_12885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY147_12890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY147_12905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY147_12910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY147_12935	COG0066	3-isopropylmalate dehydratase activity
FY147_12940	COG0473	3-isopropylmalate dehydrogenase activity
FY147_12945	COG1858	cytochrome C peroxidase
FY147_12950	COG1797	cobyrinic acid a,c-diamide synthase activity
FY147_12960	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY147_13025	COG1492	cobalamin metabolic process
FY147_13040	COG4948	Mandelate Racemase Muconate Lactonizing
FY147_13045	COG3254	rhamnose metabolic process
FY147_13055	COG1063	alcohol dehydrogenase
FY147_13080	COG1129	ABC transporter
FY147_13085	COG2186	Transcriptional regulator
FY147_13090	COG2721	sulfolactate sulfo-lyase activity
FY147_13095	COG0138	bifunctional purine biosynthesis protein purh
FY147_13105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY147_13105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY147_13110	COG0501	Belongs to the peptidase M48B family
FY147_13130	COG0357	Ribosomal RNA small subunit methyltransferase G
FY147_13135	COG0445	tRNA wobble uridine modification
FY147_13140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY147_13145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY147_13150	COG1981	membrane
FY147_13155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY147_13160	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY147_13165	COG0424	maF-like protein
FY147_13170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY147_13175	COG0237	dephospho-CoA kinase activity
FY147_13185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY147_13190	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY147_13200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY147_13225	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY147_13240	COG0135	phosphoribosylanthranilate isomerase activity
FY147_13245	COG0133	tryptophan synthase activity
FY147_13250	COG0159	tryptophan synthase activity
FY147_13255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY147_13270	COG1074	ATP-dependent DNA helicase activity
FY147_13280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY147_13285	COG0802	atpase or kinase
FY147_13290	COG2205	protein histidine kinase activity
FY147_13295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY147_13300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY147_13305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY147_13305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY147_13310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY147_13315	COG0642	Histidine kinase
FY147_13320	COG0745	RESPONSE REGULATOR receiver
FY147_13325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY147_13335	COG1652	LysM domain
FY147_13340	COG1072	(Pantothenic acid kinase))
FY147_13345	COG0140	phosphoribosyl-ATP diphosphatase activity
FY147_13350	COG0107	imidazoleglycerol-phosphate synthase activity
FY147_13355	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY147_13360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY147_13370	COG0131	Imidazoleglycerol-phosphate dehydratase
FY147_13375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY147_13380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY147_13390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY147_13405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY147_13415	COG1643	Atp-dependent helicase
FY147_13460	COG1940	carbohydrate kinase activity
FY147_13480	COG1072	(Pantothenic acid kinase))
FY147_13490	COG1780	Probably involved in ribonucleotide reductase function
FY147_13510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY147_13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_13550	COG2813	Specifically methylates the guanine in position
FY147_13555	COG1185	polyribonucleotide nucleotidyltransferase activity
FY147_13560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY147_13565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY147_13570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY147_13575	COG3064	Membrane
FY147_13575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY147_13590	COG0779	Required for maturation of 30S ribosomal subunits
FY147_13595	COG2814	Major facilitator Superfamily
FY147_13605	COG2951	lytic endotransglycosylase activity
FY147_13610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY147_13620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY147_13625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY147_13640	COG2816	NAD+ diphosphatase activity
FY147_13645	COG0077	Prephenate dehydratase
FY147_13645	COG1605	Chorismate mutase
FY147_13650	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY147_13655	COG3474	cytochrome
FY147_13665	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY147_13670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY147_13675	COG1278	Cold shock
FY147_13680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY147_13690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY147_13690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY147_13695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY147_13725	COG2900	Belongs to the SlyX family
FY147_13735	COG0484	heat shock protein binding
FY147_13740	COG0443	Heat shock 70 kDa protein
FY147_13755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY147_13760	COG1744	ABC transporter substrate-binding protein PnrA-like
FY147_13765	COG3845	ABC transporter
FY147_13770	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY147_13775	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY147_13780	COG0295	cytidine deaminase activity
FY147_13790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY147_13795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY147_13805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY147_13810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY147_13815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY147_13825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY147_13830	COG1845	cytochrome c oxidase, subunit III
FY147_13835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY147_13840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY147_13845	COG0477	Major facilitator Superfamily
FY147_13850	COG0067	glutamate synthase
FY147_13850	COG0069	glutamate synthase activity
FY147_13850	COG0070	glutamate synthase
FY147_13855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY147_13870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY147_13880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY147_13910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_13930	COG0848	biopolymer transport protein
FY147_13940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY147_13955	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY147_13960	COG3454	Phosphonate metabolism
FY147_13965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY147_13970	COG3639	organic phosphonate transmembrane transporter activity
FY147_13975	COG3639	organic phosphonate transmembrane transporter activity
FY147_13985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY147_13995	COG4778	phosphonate C-P lyase system protein PhnL
FY147_14000	COG4107	phosphonate C-P lyase system protein PhnK
FY147_14005	COG3627	carbon phosphorus lyase activity
FY147_14010	COG3626	phosphonate metabolism
FY147_14015	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY147_14020	COG3624	Phosphonate C-P lyase system protein PhnG
FY147_14025	COG2188	Transcriptional regulator
FY147_14030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY147_14035	COG0837	glucose binding
FY147_14040	COG1803	Methylglyoxal synthase
FY147_14045	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY147_14050	COG4166	transmembrane transport
FY147_14055	COG4174	ABC transporter (Permease)
FY147_14060	COG4239	(ABC) transporter, permease
FY147_14065	COG4172	Belongs to the ABC transporter superfamily
FY147_14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_14075	COG0174	glutamine synthetase
FY147_14080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_14085	COG3265	gluconokinase activity
FY147_14090	COG1174	glycine betaine transport
FY147_14095	COG1125	glycine betaine transport
FY147_14100	COG1174	glycine betaine transport
FY147_14105	COG1732	Glycine betaine
FY147_14115	COG1959	2 iron, 2 sulfur cluster binding
FY147_14120	COG1840	ABC-type Fe3 transport system, periplasmic component
FY147_14130	COG4269	membrane
FY147_14145	COG0697	spore germination
FY147_14160	COG0791	NLP P60 protein
FY147_14170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY147_14175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY147_14210	COG4964	Belongs to the GSP D family
FY147_14255	COG3422	double-strand break repair
FY147_14260	COG3757	hydrolase, family 25
FY147_14265	COG0697	spore germination
FY147_14270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY147_14285	COG0492	ferredoxin-NADP+ reductase activity
FY147_14300	COG0481	GTPase activity
FY147_14305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY147_14320	COG1396	sequence-specific DNA binding
FY147_14335	COG2169	Transcriptional regulator
FY147_14335	COG1917	Cupin 2, conserved barrel domain protein
FY147_14340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY147_14365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY147_14370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY147_14375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY147_14385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY147_14390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY147_14390	COG0072	phenylalanine-tRNA ligase activity
FY147_14395	COG0667	Aldo Keto reductase
FY147_14415	COG4977	sequence-specific DNA binding
FY147_14440	COG1570	exodeoxyribonuclease VII activity
FY147_14445	COG4948	Mandelate Racemase Muconate Lactonizing
FY147_14455	COG1846	Transcriptional regulator
FY147_14460	COG0697	spore germination
FY147_14465	COG2309	aminopeptidase activity
FY147_14475	COG1393	Belongs to the ArsC family
FY147_14490	COG1309	transcriptional regulator
FY147_14500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY147_14500	COG0519	Catalyzes the synthesis of GMP from XMP
FY147_14515	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY147_14545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY147_14555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY147_14565	COG1968	undecaprenyl-diphosphatase activity
FY147_14580	COG0284	orotidine-5'-phosphate decarboxylase activity
FY147_14590	COG3963	phosphatidate phosphatase activity
FY147_14600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY147_14605	COG0792	nuclease activity
FY147_14620	COG1175	transmembrane transport
FY147_14625	COG0395	ABC-type sugar transport system, permease component
FY147_14630	COG3842	ATPase activity
FY147_14640	COG0189	ligase activity
FY147_14645	COG0606	chelatase, subunit chli
FY147_14650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY147_14655	COG1280	lysine exporter protein (LysE YggA)
FY147_14660	COG0756	dUTP diphosphatase activity
FY147_14665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY147_14670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY147_14685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY147_14690	COG2226	methyltransferase
FY147_14695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY147_14700	COG1024	Enoyl-CoA hydratase
FY147_14705	COG0268	Binds directly to 16S ribosomal RNA
FY147_14745	COG1278	Cold shock
FY147_14785	COG0411	ABC transporter
FY147_14790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY147_14795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY147_14800	COG1454	alcohol dehydrogenase
FY147_14805	COG0747	negative chemotaxis
FY147_14810	COG0601	transmembrane transport
FY147_14820	COG4608	Belongs to the ABC transporter superfamily
FY147_14825	COG1349	DNA-binding transcription factor activity
FY147_14830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY147_14855	COG4302	ethanolamine ammonia-lyase activity
FY147_14860	COG0025	NhaP-type Na H and K H
FY147_14865	COG4106	trans-aconitate 2-methyltransferase activity
FY147_14875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_14880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_14885	COG0601	transmembrane transport
FY147_14890	COG0747	negative chemotaxis
FY147_14910	COG4172	Belongs to the ABC transporter superfamily
FY147_14935	COG0785	Cytochrome C biogenesis protein
FY147_14935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY147_14945	COG0596	Alpha beta hydrolase
FY147_14960	COG1764	response to oxidative stress
FY147_14970	COG0596	Alpha beta hydrolase
FY147_14985	COG0783	Belongs to the Dps family
FY147_14990	COG0243	molybdopterin cofactor binding
FY147_15000	COG4566	intracellular signal transduction
FY147_15005	COG4566	intracellular signal transduction
FY147_15015	COG2140	Oxalate decarboxylase
FY147_15030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY147_15030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY147_15035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY147_15045	COG1414	Transcriptional regulator
FY147_15060	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_15080	COG1522	sequence-specific DNA binding
FY147_15105	COG0628	permease
FY147_15115	COG2235	arginine
FY147_15150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY147_15160	COG0702	epimerase
FY147_15165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY147_15170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_15175	COG0745	RESPONSE REGULATOR receiver
FY147_15180	COG5002	protein histidine kinase activity
FY147_15195	COG2233	PERMEase
FY147_15255	COG0395	ABC-type sugar transport system, permease component
FY147_15260	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_15270	COG3842	ATPase activity
FY147_15305	COG1653	transport
FY147_15315	COG0395	ABC-type sugar transport system, permease component
FY147_15320	COG3842	ATPase activity
FY147_15335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY147_15340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_15345	COG1116	anion transmembrane transporter activity
FY147_15350	COG0395	ABC-type sugar transport system, permease component
FY147_15355	COG1175	transmembrane transport
FY147_15385	COG1609	Transcriptional regulator
FY147_15400	COG1082	Xylose isomerase domain protein TIM barrel
FY147_15405	COG3842	ATPase activity
FY147_15410	COG0395	ABC-type sugar transport system, permease component
FY147_15415	COG1175	transmembrane transport
FY147_15420	COG1653	transport
FY147_15425	COG1309	transcriptional regulator
FY147_15430	COG0673	inositol 2-dehydrogenase activity
FY147_15445	COG0673	inositol 2-dehydrogenase activity
FY147_15450	COG1278	Cold shock
FY147_15460	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY147_15480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY147_15485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY147_15500	COG3842	ATPase activity
FY147_15505	COG0395	ABC-type sugar transport system, permease component
FY147_15510	COG1175	transmembrane transport
FY147_15520	COG3618	amidohydrolase
FY147_15525	COG4948	Mandelate Racemase Muconate Lactonizing
FY147_15530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_15535	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_15540	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY147_15545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY147_15550	COG2186	Transcriptional regulator
FY147_15565	COG0667	Aldo Keto reductase
FY147_15595	COG4977	sequence-specific DNA binding
FY147_15600	COG2223	nitrite transmembrane transporter activity
FY147_15605	COG1609	Transcriptional regulator
FY147_15610	COG1063	alcohol dehydrogenase
FY147_15615	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_15625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_15630	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY147_15635	COG1175	transmembrane transport
FY147_15640	COG0395	ABC-type sugar transport system, permease component
FY147_15655	COG0395	ABC-type sugar transport system, permease component
FY147_15665	COG2182	Extracellular solute-binding protein
FY147_15670	COG0626	cystathionine gamma-synthase activity
FY147_15685	COG0454	-acetyltransferase
FY147_15690	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY147_15700	COG1121	(ABC) transporter
FY147_15705	COG0523	cobalamin synthesis protein
FY147_15720	COG0523	cobalamin synthesis protein
FY147_15725	COG1653	transport
FY147_15730	COG1175	transmembrane transport
FY147_15735	COG0395	ABC-type sugar transport system, permease component
FY147_15740	COG3842	ATPase activity
FY147_15750	COG3047	cAMP biosynthetic process
FY147_15775	COG0583	DNA-binding transcription factor activity
FY147_15780	COG1879	ABC-type sugar transport system periplasmic component
FY147_15785	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_15790	COG1129	ABC transporter
FY147_15800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY147_15805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_15815	COG3257	ureidoglycine aminohydrolase activity
FY147_15825	COG5001	Diguanylate cyclase
FY147_15830	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY147_15840	COG0747	negative chemotaxis
FY147_15845	COG0601	transmembrane transport
FY147_15850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_15860	COG4608	Belongs to the ABC transporter superfamily
FY147_15865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY147_15880	COG0346	lactoylglutathione lyase activity
FY147_15890	COG0129	dihydroxy-acid dehydratase activity
FY147_15895	COG1879	ABC-type sugar transport system periplasmic component
FY147_15900	COG1129	ABC transporter
FY147_15905	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_15910	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_15915	COG2186	Transcriptional regulator
FY147_15930	COG2226	methyltransferase
FY147_15935	COG0587	DNA-directed DNA polymerase activity
FY147_15965	COG0673	inositol 2-dehydrogenase activity
FY147_15975	COG3842	ATPase activity
FY147_15980	COG0395	ABC-type sugar transport system, permease component
FY147_15985	COG1175	transmembrane transport
FY147_15990	COG1653	transport
FY147_16000	COG0673	inositol 2-dehydrogenase activity
FY147_16015	COG5001	Diguanylate cyclase
FY147_16025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_16030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY147_16035	COG2894	cell division
FY147_16040	COG0850	regulation of cytokinetic process
FY147_16045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY147_16050	COG2186	Transcriptional regulator
FY147_16055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY147_16065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY147_16070	COG1063	alcohol dehydrogenase
FY147_16075	COG1312	Catalyzes the dehydration of D-mannonate
FY147_16095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY147_16100	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY147_16100	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY147_16105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_16120	COG0625	glutathione transferase activity
FY147_16125	COG4172	Belongs to the ABC transporter superfamily
FY147_16130	COG1921	L-seryl-tRNASec selenium transferase activity
FY147_16145	COG3964	amidohydrolase
FY147_16155	COG0601	transmembrane transport
FY147_16160	COG0747	negative chemotaxis
FY147_16165	COG0438	transferase activity, transferring glycosyl groups
FY147_16200	COG4989	oxidoreductase activity
FY147_16210	COG2188	Transcriptional regulator
FY147_16215	COG3842	ATPase activity
FY147_16220	COG1653	transport
FY147_16225	COG1175	transmembrane transport
FY147_16230	COG0395	ABC-type sugar transport system, permease component
FY147_16235	COG1501	Belongs to the glycosyl hydrolase 31 family
FY147_16245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_16250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY147_16255	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY147_16260	COG0352	thiamine-phosphate diphosphorylase activity
FY147_16265	COG0351	phosphomethylpyrimidine kinase
FY147_16270	COG1522	sequence-specific DNA binding
FY147_16275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY147_16280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_16295	COG2204	response regulator
FY147_16300	COG4191	Histidine kinase
FY147_16305	COG1301	dicarboxylic acid transport
FY147_16310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY147_16315	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_16325	COG1473	amidohydrolase
FY147_16345	COG1215	transferase activity, transferring glycosyl groups
FY147_16355	COG2942	2-epimerase
FY147_16380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY147_16390	COG2197	response regulator
FY147_16420	COG3307	-O-antigen
FY147_16425	COG1596	polysaccharide export
FY147_16430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY147_16440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY147_16445	COG0840	transmembrane signaling receptor activity
FY147_16445	COG2972	Histidine kinase
FY147_16450	COG1376	ErfK ybiS ycfS ynhG family protein
FY147_16460	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_16470	COG2094	Belongs to the DNA glycosylase MPG family
FY147_16485	COG1609	Transcriptional regulator
FY147_16490	COG1653	transport
FY147_16505	COG3842	ATPase activity
FY147_16515	COG0673	inositol 2-dehydrogenase activity
FY147_16520	COG0602	queuosine metabolic process
FY147_16525	COG0720	synthase
FY147_16530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY147_16535	COG0673	inositol 2-dehydrogenase activity
FY147_16550	COG0395	ABC-type sugar transport system, permease component
FY147_16555	COG1175	transmembrane transport
FY147_16580	COG0583	DNA-binding transcription factor activity
FY147_16585	COG0281	malic enzyme
FY147_16585	COG0280	phosphate acetyltransferase
FY147_16600	COG0765	amino acid transport
FY147_16605	COG1126	abc transporter atp-binding protein
FY147_16610	COG2079	MmgE PrpD family protein
FY147_16615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_16625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_16640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY147_16650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY147_16655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY147_16660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_16665	COG1129	ABC transporter
FY147_16680	COG1473	amidohydrolase
FY147_16685	COG0747	negative chemotaxis
FY147_16700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_16705	COG0601	transmembrane transport
FY147_16710	COG0583	DNA-binding transcription factor activity
FY147_16715	COG1446	asparaginase
FY147_16730	COG0747	negative chemotaxis
FY147_16750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_16755	COG0601	transmembrane transport
FY147_16760	COG2197	response regulator
FY147_16765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY147_16770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY147_16785	COG0395	ABC-type sugar transport system, permease component
FY147_16790	COG1175	transmembrane transport
FY147_16800	COG0673	inositol 2-dehydrogenase activity
FY147_16805	COG0673	inositol 2-dehydrogenase activity
FY147_16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_16830	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY147_16850	COG1595	DNA-templated transcription, initiation
FY147_16855	COG1120	ATPase activity
FY147_16860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_16875	COG2226	methyltransferase
FY147_16885	COG1120	ATPase activity
FY147_16890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_16935	COG1012	belongs to the aldehyde dehydrogenase family
FY147_16940	COG0473	3-isopropylmalate dehydrogenase activity
FY147_16945	COG1012	belongs to the aldehyde dehydrogenase family
FY147_16950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_16985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_16990	COG4172	Belongs to the ABC transporter superfamily
FY147_16995	COG1522	sequence-specific DNA binding
FY147_17005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_17020	COG0583	DNA-binding transcription factor activity
FY147_17030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_17035	COG1126	abc transporter atp-binding protein
FY147_17045	COG1473	amidohydrolase
FY147_17050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17060	COG1959	2 iron, 2 sulfur cluster binding
FY147_17070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY147_17075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17105	COG1960	acyl-CoA dehydrogenase activity
FY147_17115	COG0747	negative chemotaxis
FY147_17130	COG0444	Belongs to the ABC transporter superfamily
FY147_17140	COG0667	Aldo Keto reductase
FY147_17150	COG0583	DNA-binding transcription factor activity
FY147_17155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17160	COG4166	transmembrane transport
FY147_17170	COG0747	negative chemotaxis
FY147_17175	COG1473	amidohydrolase
FY147_17180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_17210	COG1733	regulation of RNA biosynthetic process
FY147_17215	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_17235	COG4608	Belongs to the ABC transporter superfamily
FY147_17240	COG0444	Belongs to the ABC transporter superfamily
FY147_17250	COG0601	transmembrane transport
FY147_17260	COG2186	Transcriptional regulator
FY147_17275	COG0300	oxidoreductase activity
FY147_17285	COG3453	Protein conserved in bacteria
FY147_17285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY147_17290	COG0640	Transcriptional regulator
FY147_17300	COG2391	methyltransferase activity
FY147_17305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY147_17315	COG0022	dehydrogenase e1 component
FY147_17325	COG1960	acyl-CoA dehydrogenase activity
FY147_17330	COG0183	Belongs to the thiolase family
FY147_17340	COG1960	acyl-CoA dehydrogenase activity
FY147_17345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY147_17365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY147_17370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY147_17375	COG4952	isomerase
FY147_17380	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_17380	COG3347	Dehydrogenase
FY147_17385	COG1349	DNA-binding transcription factor activity
FY147_17400	COG1129	ABC transporter
FY147_17405	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_17410	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_17415	COG3254	rhamnose metabolic process
FY147_17430	COG2264	protein methyltransferase activity
FY147_17435	COG5001	Diguanylate cyclase
FY147_17450	COG4335	DNA alkylation repair
FY147_17455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY147_17460	COG4208	sulfate ABC transporter
FY147_17470	COG4150	thiosulfate binding
FY147_17475	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY147_17490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY147_17500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY147_17510	COG1040	competence protein
FY147_17515	COG2226	methyltransferase
FY147_17530	COG0494	nUDIX hydrolase
FY147_17540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY147_17545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY147_17550	COG0653	protein targeting
FY147_17555	COG0697	spore germination
FY147_17620	COG2244	polysaccharide biosynthetic process
FY147_17635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY147_17645	COG0489	protein tyrosine kinase activity
FY147_17645	COG3206	protein involved in exopolysaccharide biosynthesis
FY147_17665	COG0438	transferase activity, transferring glycosyl groups
FY147_17670	COG0438	transferase activity, transferring glycosyl groups
FY147_17685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY147_17690	COG2273	Hydrolase Family 16
FY147_17690	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY147_17705	COG3842	ATPase activity
FY147_17710	COG3833	ABC-type maltose transport systems, permease component
FY147_17765	COG1396	sequence-specific DNA binding
FY147_17775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY147_17780	COG1129	ABC transporter
FY147_17785	COG4214	carbohydrate transport
FY147_17790	COG4213	ABC transporter substrate-binding protein
FY147_17805	COG0346	lactoylglutathione lyase activity
FY147_17810	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY147_17810	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY147_17815	COG4770	biotin carboxylase activity
FY147_17830	COG0625	glutathione transferase activity
FY147_17835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY147_17840	COG3800	Transcriptional regulator
FY147_17840	COG1396	sequence-specific DNA binding
FY147_17850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY147_17860	COG0300	oxidoreductase activity
FY147_17870	COG2096	Adenosyltransferase
FY147_17880	COG2086	electron transfer activity
FY147_17890	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY147_17900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY147_17905	COG0165	Argininosuccinate lyase
FY147_17940	COG2884	Cell division ATP-binding protein ftsE
FY147_17960	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY147_17970	COG0287	Prephenate dehydrogenase
FY147_17975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY147_17980	COG2226	methyltransferase
FY147_17985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY147_18005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY147_18010	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY147_18050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY147_18055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY147_18065	COG4974	Belongs to the 'phage' integrase family
FY147_18070	COG0825	malonyl-CoA metabolic process
FY147_18075	COG3034	peptidoglycan biosynthetic process
FY147_18080	COG0425	Belongs to the sulfur carrier protein TusA family
FY147_18080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY147_18085	COG0523	cobalamin synthesis protein
FY147_18090	COG1686	Belongs to the peptidase S11 family
FY147_18095	COG1473	amidohydrolase
FY147_18105	COG4953	penicillin-binding protein 1C
FY147_18110	COG2373	Large extracellular alpha-helical protein
FY147_18115	COG2835	tetraacyldisaccharide 4'-kinase activity
FY147_18150	COG0482	sulfurtransferase activity
FY147_18165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY147_18180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY147_18185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY147_18190	COG0037	tRNA processing
FY147_18200	COG2885	chlorophyll binding
FY147_18205	COG0823	Involved in the tonB-independent uptake of proteins
FY147_18225	COG0824	Thioesterase
FY147_18235	COG0494	nUDIX hydrolase
FY147_18250	COG2255	four-way junction helicase activity
FY147_18255	COG0632	four-way junction helicase activity
FY147_18260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY147_18265	COG2972	Histidine kinase
FY147_18265	COG0840	transmembrane signaling receptor activity
FY147_18270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_18275	COG0217	transcriptional regulatory protein
FY147_18290	COG1692	metallophosphoesterase
FY147_18300	COG1253	flavin adenine dinucleotide binding
FY147_18340	COG0126	phosphoglycerate kinase activity
FY147_18345	COG3588	fructose-bisphosphate aldolase
FY147_18365	COG0254	rRNA binding
FY147_18370	COG1132	(ABC) transporter
FY147_18390	COG0483	inositol monophosphate 1-phosphatase activity
FY147_18420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY147_18425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY147_18430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY147_18435	COG0457	Tetratricopeptide repeat
FY147_18440	COG3750	Belongs to the UPF0335 family
FY147_18460	COG0469	pyruvate kinase activity
FY147_18465	COG3108	Peptidase M15
FY147_18475	COG1164	Oligoendopeptidase f
FY147_18480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY147_18490	COG5310	Homospermidine synthase
FY147_18500	COG0737	Belongs to the 5'-nucleotidase family
FY147_18505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY147_18510	COG0330	HflC and HflK could
FY147_18540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY147_18545	COG2951	lytic endotransglycosylase activity
FY147_18555	COG0745	RESPONSE REGULATOR receiver
FY147_18560	COG2205	protein histidine kinase activity
FY147_18575	COG0067	glutamate synthase
FY147_18575	COG0069	glutamate synthase activity
FY147_18575	COG0070	glutamate synthase
FY147_18590	COG2205	protein histidine kinase activity
FY147_18595	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY147_18600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY147_18605	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY147_18615	COG0252	asparaginase activity
FY147_18625	COG1027	Aspartate ammonia-lyase
FY147_18630	COG2186	Transcriptional regulator
FY147_18650	COG1309	transcriptional regulator
FY147_18670	COG4176	ABC-type proline glycine betaine transport system permease component
FY147_18675	COG3448	diguanylate cyclase activity
FY147_18675	COG4175	Glycine betaine
FY147_18680	COG2986	histidine ammonia-lyase
FY147_18685	COG1609	Transcriptional regulator
FY147_18705	COG1082	Xylose isomerase domain protein TIM barrel
FY147_18710	COG0673	inositol 2-dehydrogenase activity
FY147_18715	COG1082	Xylose isomerase domain protein TIM barrel
FY147_18720	COG1082	Xylose isomerase domain protein TIM barrel
FY147_18745	COG0732	type I restriction modification DNA specificity domain
FY147_18750	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FY147_18770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY147_18795	COG1078	dGTPase activity
FY147_18805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_18815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_18820	COG0601	transmembrane transport
FY147_18825	COG0747	negative chemotaxis
FY147_18835	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY147_18840	COG1454	alcohol dehydrogenase
FY147_18880	COG2307	Protein conserved in bacteria
FY147_18880	COG2308	Evidence 4 Homologs of previously reported genes of
FY147_18895	COG0488	(ABC) transporter
FY147_18900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY147_18905	COG2186	Transcriptional regulator
FY147_18920	COG1175	transmembrane transport
FY147_18925	COG0395	ABC-type sugar transport system, permease component
FY147_18935	COG3842	ATPase activity
FY147_18960	COG1304	FMN binding
FY147_18975	COG1063	alcohol dehydrogenase
FY147_18980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY147_18985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_18995	COG0765	amino acid transport
FY147_19000	COG0765	amino acid transport
FY147_19005	COG4221	oxidoreductase activity
FY147_19010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY147_19015	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_19020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY147_19035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY147_19050	COG0697	spore germination
FY147_19055	COG0697	spore germination
FY147_19060	COG0511	ligase activity, forming carbon-carbon bonds
FY147_19065	COG0439	Biotin carboxylase
FY147_19075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY147_19080	COG1984	allophanate hydrolase subunit 2
FY147_19085	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY147_19090	COG3842	ATPase activity
FY147_19100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY147_19110	COG0436	Aminotransferase
FY147_19125	COG0840	transmembrane signaling receptor activity
FY147_19125	COG2972	Histidine kinase
FY147_19130	COG1070	Carbohydrate kinase
FY147_19135	COG1830	Aldolase
FY147_19140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY147_19145	COG0667	Aldo Keto reductase
FY147_19155	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_19160	COG1129	ABC transporter
FY147_19165	COG1879	ABC-type sugar transport system periplasmic component
FY147_19210	COG0071	Belongs to the small heat shock protein (HSP20) family
FY147_19225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY147_19240	COG0395	ABC-type sugar transport system, permease component
FY147_19255	COG3842	ATPase activity
FY147_19270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY147_19270	COG1648	precorrin-2 dehydrogenase activity
FY147_19275	COG0243	molybdopterin cofactor binding
FY147_19285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY147_19290	COG1116	anion transmembrane transporter activity
FY147_19295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_19300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY147_19310	COG3707	response regulator
FY147_19315	COG1802	Transcriptional regulator
FY147_19320	COG1914	H( )-stimulated, divalent metal cation uptake system
FY147_19325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY147_19330	COG4336	lyase activity
FY147_19335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY147_19340	COG4770	biotin carboxylase activity
FY147_19345	COG0366	Alpha amylase catalytic
FY147_19355	COG4771	TonB-dependent receptor
FY147_19360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY147_19380	COG1414	Transcriptional regulator
FY147_19385	COG1475	DNA binding
FY147_19390	COG1192	Involved in chromosome partitioning
FY147_19420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY147_19430	COG2986	histidine ammonia-lyase
FY147_19435	COG1228	amidohydrolase
FY147_19440	COG0402	S-adenosylhomocysteine deaminase activity
FY147_19490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY147_19500	COG1280	lysine exporter protein (LysE YggA)
FY147_19515	COG1309	transcriptional regulator
FY147_19520	COG4221	oxidoreductase activity
FY147_19525	COG1902	pentaerythritol trinitrate reductase activity
FY147_19530	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_19535	COG2267	carboxylic ester hydrolase activity
FY147_19565	COG1278	Cold shock
FY147_19585	COG0753	catalase activity
FY147_19610	COG3920	Histidine kinase
FY147_19615	COG1280	lysine exporter protein (LysE YggA)
FY147_19635	COG0583	DNA-binding transcription factor activity
FY147_19670	COG0583	DNA-binding transcription factor activity
FY147_19680	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_19685	COG1846	Transcriptional regulator
FY147_19705	COG2186	Transcriptional regulator
FY147_19715	COG1126	abc transporter atp-binding protein
FY147_19725	COG0765	amino acid transport
FY147_19730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_19745	COG0436	Aminotransferase
FY147_19750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_19780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY147_19785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_19790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_19800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_19805	COG0747	negative chemotaxis
FY147_19810	COG0747	negative chemotaxis
FY147_19820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_19830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_19840	COG1129	ABC transporter
FY147_19845	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_19850	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_19875	COG0667	Aldo Keto reductase
FY147_19890	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_19895	COG1129	ABC transporter
FY147_19900	COG4213	ABC transporter substrate-binding protein
FY147_19920	COG4608	Belongs to the ABC transporter superfamily
FY147_19925	COG0444	Belongs to the ABC transporter superfamily
FY147_19930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_19935	COG0601	transmembrane transport
FY147_19940	COG0747	negative chemotaxis
FY147_19965	COG0765	amino acid transport
FY147_19970	COG4597	amino acid ABC transporter
FY147_19975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_19990	COG3177	Filamentation induced by cAMP protein fic
FY147_20015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_20045	COG3209	COG3209 Rhs family protein
FY147_20065	COG0745	RESPONSE REGULATOR receiver
FY147_20075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_20080	COG0577	efflux transmembrane transporter activity
FY147_20080	COG1136	(ABC) transporter
FY147_20090	COG1733	regulation of RNA biosynthetic process
FY147_20125	COG0534	Mate efflux family protein
FY147_20140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY147_20145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY147_20155	COG1566	PFAM secretion protein HlyD family protein
FY147_20165	COG0625	glutathione transferase activity
FY147_20170	COG4221	oxidoreductase activity
FY147_20175	COG4172	Belongs to the ABC transporter superfamily
FY147_20180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_20185	COG0601	transmembrane transport
FY147_20190	COG4166	transmembrane transport
FY147_20195	COG0395	ABC-type sugar transport system, permease component
FY147_20210	COG1566	PFAM secretion protein HlyD family protein
FY147_20225	COG2207	Transcriptional regulator
FY147_20230	COG1309	transcriptional regulator
FY147_20235	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_20260	COG1846	Transcriptional regulator
FY147_20265	COG0583	DNA-binding transcription factor activity
FY147_20270	COG2828	Protein conserved in bacteria
FY147_20285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_20300	COG0840	transmembrane signaling receptor activity
FY147_20320	COG1215	transferase activity, transferring glycosyl groups
FY147_20350	COG0583	DNA-binding transcription factor activity
FY147_20355	COG0346	lactoylglutathione lyase activity
FY147_20370	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY147_20390	COG0583	DNA-binding transcription factor activity
FY147_20395	COG0477	Major facilitator Superfamily
FY147_20405	COG2205	protein histidine kinase activity
FY147_20410	COG0745	RESPONSE REGULATOR receiver
FY147_20415	COG0671	phosphoesterase, PA-phosphatase related
FY147_20465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY147_20470	COG0156	8-amino-7-oxononanoate synthase activity
FY147_20475	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY147_20480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY147_20485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY147_20500	COG0010	Belongs to the arginase family
FY147_20510	COG0697	spore germination
FY147_20515	COG0673	inositol 2-dehydrogenase activity
FY147_20540	COG0477	Major facilitator Superfamily
FY147_20555	COG2194	sulfuric ester hydrolase activity
FY147_20565	COG0583	DNA-binding transcription factor activity
FY147_20570	COG4774	siderophore transport
FY147_20585	COG1120	ATPase activity
FY147_20595	COG3474	cytochrome
FY147_20600	COG2137	regulation of response to DNA damage stimulus
FY147_20605	COG3386	PFAM SMP-30 Gluconolaconase
FY147_20615	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_20620	COG1129	ABC transporter
FY147_20625	COG1879	ABC-type sugar transport system periplasmic component
FY147_20630	COG4585	Histidine kinase
FY147_20635	COG2197	response regulator
FY147_20645	COG2133	pyrroloquinoline quinone binding
FY147_20655	COG0500	methyltransferase
FY147_20660	COG0564	pseudouridine synthase activity
FY147_20675	COG4175	Glycine betaine
FY147_20675	COG3448	diguanylate cyclase activity
FY147_20680	COG4176	ABC-type proline glycine betaine transport system permease component
FY147_20695	COG4191	Histidine kinase
FY147_20695	COG0784	Response regulator, receiver
FY147_20700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY147_20705	COG0489	protein tyrosine kinase activity
FY147_20705	COG3206	protein involved in exopolysaccharide biosynthesis
FY147_20710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY147_20715	COG1215	transferase activity, transferring glycosyl groups
FY147_20720	COG1215	transferase activity, transferring glycosyl groups
FY147_20725	COG1215	transferase activity, transferring glycosyl groups
FY147_20730	COG0438	transferase activity, transferring glycosyl groups
FY147_20735	COG2273	Hydrolase Family 16
FY147_20740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY147_20745	COG2244	polysaccharide biosynthetic process
FY147_20750	COG0463	Glycosyl transferase, family 2
FY147_20755	COG2327	Polysaccharide pyruvyl transferase
FY147_20760	COG1215	transferase activity, transferring glycosyl groups
FY147_20780	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY147_20785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_20800	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY147_20800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY147_20830	COG1523	belongs to the glycosyl hydrolase 13 family
FY147_20835	COG0033	Phosphoglucomutase
FY147_20840	COG0297	glycogen (starch) synthase activity
FY147_20845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY147_20850	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY147_20855	COG0058	SHG alpha-glucan phosphorylase activity
FY147_20870	COG1794	racemase activity, acting on amino acids and derivatives
FY147_20875	COG1522	sequence-specific DNA binding
FY147_20885	COG2084	Dehydrogenase
FY147_20890	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_20895	COG1063	alcohol dehydrogenase
FY147_20905	COG4988	ABC transporter
FY147_20910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY147_20920	COG1294	oxidase, subunit
FY147_20950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY147_20955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY147_20985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY147_20990	COG0539	negative regulation of cytoplasmic translation
FY147_21020	COG4221	oxidoreductase activity
FY147_21030	COG0747	negative chemotaxis
FY147_21035	COG0601	transmembrane transport
FY147_21040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_21045	COG0444	Belongs to the ABC transporter superfamily
FY147_21050	COG4608	Belongs to the ABC transporter superfamily
FY147_21055	COG0246	Mannitol dehydrogenase
FY147_21070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_21115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY147_21120	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_21135	COG4993	Dehydrogenase
FY147_21140	COG3685	Protein conserved in bacteria
FY147_21170	COG0693	protein deglycase activity
FY147_21190	COG0189	ligase activity
FY147_21195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY147_21200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY147_21215	COG0435	Glutathione S-transferase
FY147_21220	COG0583	DNA-binding transcription factor activity
FY147_21225	COG1012	belongs to the aldehyde dehydrogenase family
FY147_21230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY147_21235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_21240	COG1116	anion transmembrane transporter activity
FY147_21250	COG1522	sequence-specific DNA binding
FY147_21265	COG0784	Response regulator, receiver
FY147_21275	COG3920	Histidine kinase
FY147_21285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY147_21300	COG0019	diaminopimelate decarboxylase activity
FY147_21315	COG0527	aspartate kinase activity
FY147_21325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY147_21330	COG2890	protein-(glutamine-N5) methyltransferase activity
FY147_21340	COG0542	response to heat
FY147_21345	COG0739	heme binding
FY147_21345	COG1196	nuclear chromosome segregation
FY147_21345	COG0741	lytic transglycosylase activity
FY147_21385	COG3609	addiction module antidote protein, CC2985 family
FY147_21490	COG2376	Dihydroxyacetone kinase
FY147_21495	COG1522	sequence-specific DNA binding
FY147_21515	COG0431	NADPH-dependent FMN reductase
FY147_21525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_21535	COG4172	Belongs to the ABC transporter superfamily
FY147_21540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_21560	COG0277	FAD linked oxidase domain protein
FY147_21580	COG0778	Nitroreductase
FY147_21610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY147_21635	COG2318	DinB family
FY147_21640	COG0583	DNA-binding transcription factor activity
FY147_21655	COG1335	isochorismatase
FY147_21680	COG3842	ATPase activity
FY147_21685	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_21690	COG1177	transmembrane transport
FY147_21695	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY147_21705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY147_21720	COG1120	ATPase activity
FY147_21725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_21730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_21735	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY147_21740	COG1629	transport
FY147_21740	COG4774	siderophore transport
FY147_21745	COG4702	Belongs to the UPF0303 family
FY147_21765	COG1024	Enoyl-CoA hydratase
FY147_21770	COG1012	belongs to the aldehyde dehydrogenase family
FY147_21775	COG1653	transport
FY147_21780	COG1175	transmembrane transport
FY147_21785	COG0395	ABC-type sugar transport system, permease component
FY147_21790	COG3842	ATPase activity
FY147_21815	COG3474	cytochrome
FY147_21820	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY147_21825	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY147_21830	COG1845	cytochrome c oxidase, subunit III
FY147_21855	COG0577	efflux transmembrane transporter activity
FY147_21855	COG1136	(ABC) transporter
FY147_21910	COG3842	ATPase activity
FY147_21920	COG1177	transmembrane transport
FY147_21925	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_21940	COG1940	carbohydrate kinase activity
FY147_21960	COG1069	ribulokinase activity
FY147_21965	COG1349	DNA-binding transcription factor activity
FY147_21970	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_21995	COG0395	ABC-type sugar transport system, permease component
FY147_22005	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_22020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY147_22025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY147_22035	COG0477	Major facilitator Superfamily
FY147_22075	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FY147_22085	COG1733	regulation of RNA biosynthetic process
FY147_22120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY147_22125	COG3938	Belongs to the proline racemase family
FY147_22130	COG4176	ABC-type proline glycine betaine transport system permease component
FY147_22140	COG3448	diguanylate cyclase activity
FY147_22140	COG4175	Glycine betaine
FY147_22150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_22155	COG1012	belongs to the aldehyde dehydrogenase family
FY147_22160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_22170	COG0047	phosphoribosylformylglycinamidine synthase activity
FY147_22175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_22185	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY147_22185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY147_22195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY147_22210	COG1309	transcriptional regulator
FY147_22225	COG1136	(ABC) transporter
FY147_22240	COG1063	alcohol dehydrogenase
FY147_22250	COG1879	ABC-type sugar transport system periplasmic component
FY147_22260	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_22280	COG0477	Major facilitator Superfamily
FY147_22410	COG3300	MHYT domain
FY147_22410	COG5001	Diguanylate cyclase
FY147_22435	COG1253	flavin adenine dinucleotide binding
FY147_22450	COG3842	ATPase activity
FY147_22455	COG0395	ABC-type sugar transport system, permease component
FY147_22460	COG1175	transmembrane transport
FY147_22465	COG1653	transport
FY147_22475	COG0673	inositol 2-dehydrogenase activity
FY147_22480	COG1609	Transcriptional regulator
FY147_22495	COG0583	DNA-binding transcription factor activity
FY147_22505	COG1879	ABC-type sugar transport system periplasmic component
FY147_22510	COG1129	ABC transporter
FY147_22515	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_22520	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_22525	COG1609	Transcriptional regulator
FY147_22535	COG0673	inositol 2-dehydrogenase activity
FY147_22595	COG0714	Associated with various cellular activities
FY147_22600	COG3256	nitric oxide reductase
FY147_22630	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY147_22635	COG3189	MarR family transcriptional regulator
FY147_22645	COG0826	peptidase U32
FY147_22670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY147_22680	COG4459	periplasmic nitrate reductase
FY147_22695	COG0243	molybdopterin cofactor binding
FY147_22705	COG3005	denitrification pathway
FY147_22720	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_22725	COG1535	isochorismatase
FY147_22725	COG3433	isochorismatase activity
FY147_22730	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY147_22735	COG1169	isochorismate synthase
FY147_22745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY147_22745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY147_22750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY147_22760	COG2375	cellular response to nickel ion
FY147_22770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_22775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_22785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_22795	COG4774	siderophore transport
FY147_22795	COG1629	transport
FY147_22800	COG1960	acyl-CoA dehydrogenase activity
FY147_22805	COG0583	DNA-binding transcription factor activity
FY147_22810	COG1609	Transcriptional regulator
FY147_22820	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_22840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY147_22845	COG0583	DNA-binding transcription factor activity
FY147_22850	COG2814	Major facilitator Superfamily
FY147_22855	COG1473	amidohydrolase
FY147_22860	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY147_22870	COG0747	negative chemotaxis
FY147_22875	COG0601	transmembrane transport
FY147_22880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_22885	COG0444	Belongs to the ABC transporter superfamily
FY147_22890	COG4608	Belongs to the ABC transporter superfamily
FY147_22895	COG0583	DNA-binding transcription factor activity
FY147_22900	COG0747	negative chemotaxis
FY147_22910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_22915	COG0154	amidase activity
FY147_22920	COG0693	protein deglycase activity
FY147_22930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_22935	COG0601	transmembrane transport
FY147_22945	COG1473	amidohydrolase
FY147_22950	COG4172	Belongs to the ABC transporter superfamily
FY147_22955	COG2390	Transcriptional regulator
FY147_22965	COG1175	transmembrane transport
FY147_22970	COG0395	ABC-type sugar transport system, permease component
FY147_22995	COG1069	ribulokinase activity
FY147_23020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY147_23040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY147_23045	COG1414	Transcriptional regulator
FY147_23050	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_23060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY147_23065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY147_23070	COG1121	(ABC) transporter
FY147_23075	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY147_23085	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY147_23090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY147_23095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY147_23100	COG0471	metal ion transport
FY147_23100	COG3273	potassium ion transport
FY147_23105	COG1253	flavin adenine dinucleotide binding
FY147_23110	COG1309	transcriptional regulator
FY147_23130	COG1609	Transcriptional regulator
FY147_23135	COG1070	Carbohydrate kinase
FY147_23140	COG2115	Belongs to the xylose isomerase family
FY147_23150	COG0778	Nitroreductase
FY147_23155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY147_23160	COG2011	ABC-type metal ion transport system permease component
FY147_23170	COG5001	Diguanylate cyclase
FY147_23170	COG3300	MHYT domain
FY147_23175	COG1054	Belongs to the UPF0176 family
FY147_23185	COG2954	triphosphatase activity
FY147_23190	COG0800	Aldolase
FY147_23210	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY147_23245	COG0523	cobalamin synthesis protein
FY147_23255	COG1846	Transcriptional regulator
FY147_23260	COG1609	Transcriptional regulator
FY147_23265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY147_23275	COG3718	enzyme involved in inositol metabolism
FY147_23285	COG3962	Belongs to the TPP enzyme family
FY147_23290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_23305	COG0411	ABC transporter
FY147_23320	COG0683	leucine binding
FY147_23335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_23345	COG0747	negative chemotaxis
FY147_23350	COG4172	Belongs to the ABC transporter superfamily
FY147_23375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY147_23380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY147_23385	COG1126	abc transporter atp-binding protein
FY147_23390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_23395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_23400	COG0765	amino acid transport
FY147_23405	COG0765	amino acid transport
FY147_23410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY147_23415	COG3485	protocatechuate 3,4-dioxygenase
FY147_23420	COG3485	protocatechuate 3,4-dioxygenase
FY147_23425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY147_23435	COG0583	DNA-binding transcription factor activity
FY147_23450	COG1414	Transcriptional regulator
FY147_23460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY147_23465	COG0183	Belongs to the thiolase family
FY147_23470	COG1609	Transcriptional regulator
FY147_23485	COG1082	Xylose isomerase domain protein TIM barrel
FY147_23490	COG0673	inositol 2-dehydrogenase activity
FY147_23500	COG1609	Transcriptional regulator
FY147_23505	COG0395	ABC-type sugar transport system, permease component
FY147_23510	COG1175	transmembrane transport
FY147_23515	COG3842	ATPase activity
FY147_23525	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY147_23545	COG2814	Major facilitator Superfamily
FY147_23550	COG4774	siderophore transport
FY147_23555	COG3712	iron ion homeostasis
FY147_23565	COG1940	carbohydrate kinase activity
FY147_23570	COG0584	glycerophosphoryl diester phosphodiesterase
FY147_23575	COG0300	oxidoreductase activity
FY147_23590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY147_23610	COG0667	Aldo Keto reductase
FY147_23615	COG0583	DNA-binding transcription factor activity
FY147_23625	COG1132	(ABC) transporter
FY147_23640	COG1442	glycosyl transferase family 8
FY147_23640	COG1216	Glycosyl transferase, family 2
FY147_23645	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY147_23655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY147_23675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY147_23680	COG3754	Rhamnan synthesis protein F
FY147_23695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY147_23700	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY147_23705	COG1088	dTDP-glucose 4,6-dehydratase activity
FY147_23710	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY147_23715	COG0210	DNA helicase
FY147_23725	COG1609	Transcriptional regulator
FY147_23730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY147_23730	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY147_23745	COG0395	ABC-type sugar transport system, permease component
FY147_23750	COG3842	ATPase activity
FY147_23760	COG0444	Belongs to the ABC transporter superfamily
FY147_23765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_23770	COG0601	transmembrane transport
FY147_23795	COG5001	Diguanylate cyclase
FY147_23795	COG3300	MHYT domain
FY147_23800	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_23810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY147_23820	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY147_23825	COG0306	phosphate transporter
FY147_23830	COG1392	Phosphate transport regulator
FY147_23845	COG1566	PFAM secretion protein HlyD family protein
FY147_23855	COG0745	RESPONSE REGULATOR receiver
FY147_23860	COG2205	protein histidine kinase activity
FY147_23875	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY147_23885	COG4774	siderophore transport
FY147_23895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_23900	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_23905	COG1120	ATPase activity
FY147_23910	COG0583	DNA-binding transcription factor activity
FY147_23920	COG3119	arylsulfatase activity
FY147_23925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY147_23930	COG3842	ATPase activity
FY147_23935	COG0165	Argininosuccinate lyase
FY147_23940	COG0395	ABC-type sugar transport system, permease component
FY147_23945	COG1175	transmembrane transport
FY147_23950	COG2182	Extracellular solute-binding protein
FY147_23955	COG1940	carbohydrate kinase activity
FY147_23980	COG1486	melibiose metabolic process
FY147_23985	COG0747	negative chemotaxis
FY147_23990	COG0601	transmembrane transport
FY147_23995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_24000	COG4172	Belongs to the ABC transporter superfamily
FY147_24005	COG1486	melibiose metabolic process
FY147_24010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY147_24015	COG0842	Transport permease protein
FY147_24015	COG1129	ABC transporter
FY147_24020	COG0842	Transport permease protein
FY147_24040	COG0784	Response regulator, receiver
FY147_24045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY147_24055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_24060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY147_24075	COG0765	amino acid transport
FY147_24085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_24095	COG3938	Belongs to the proline racemase family
FY147_24110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_24115	COG0765	amino acid transport
FY147_24120	COG0765	amino acid transport
FY147_24130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY147_24145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY147_24165	COG3383	formate dehydrogenase (NAD+) activity
FY147_24175	COG2223	nitrite transmembrane transporter activity
FY147_24180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY147_24190	COG2186	Transcriptional regulator
FY147_24195	COG0747	negative chemotaxis
FY147_24200	COG0601	transmembrane transport
FY147_24205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_24210	COG4172	Belongs to the ABC transporter superfamily
FY147_24215	COG4948	Mandelate Racemase Muconate Lactonizing
FY147_24225	COG2186	Transcriptional regulator
FY147_24230	COG0747	negative chemotaxis
FY147_24235	COG0601	transmembrane transport
FY147_24240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_24245	COG0405	Gamma-glutamyltransferase
FY147_24255	COG0483	inositol monophosphate 1-phosphatase activity
FY147_24265	COG3842	ATPase activity
FY147_24270	COG0395	ABC-type sugar transport system, permease component
FY147_24290	COG3237	CsbD-like
FY147_24300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY147_24305	COG3181	Tripartite tricarboxylate transporter family receptor
FY147_24310	COG5265	(ABC) transporter
FY147_24315	COG0488	(ABC) transporter
FY147_24340	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY147_24345	COG0110	maltose O-acetyltransferase activity
FY147_24355	COG1063	alcohol dehydrogenase
FY147_24360	COG3284	Transcriptional regulator
FY147_24380	COG1129	ABC transporter
FY147_24385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_24390	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_24400	COG0572	uridine kinase
FY147_24405	COG1082	Xylose isomerase domain protein TIM barrel
FY147_24430	COG4178	(ABC) transporter
FY147_24465	COG0640	Transcriptional regulator
FY147_24480	COG2274	protein secretion by the type I secretion system
FY147_24495	COG1192	Involved in chromosome partitioning
FY147_24500	COG1475	DNA binding
FY147_24505	COG0640	Transcriptional regulator
FY147_24520	COG1126	abc transporter atp-binding protein
FY147_24525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_24530	COG1609	Transcriptional regulator
FY147_24565	COG3239	Fatty acid desaturase
FY147_24575	COG1278	Cold shock
FY147_24650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY147_24650	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY147_24690	COG4191	Histidine kinase
FY147_24695	COG1132	(ABC) transporter
FY147_24705	COG0640	Transcriptional regulator
FY147_24735	COG4977	sequence-specific DNA binding
FY147_24740	COG2211	Major facilitator Superfamily
FY147_24745	COG2807	transmembrane transport
FY147_24750	COG1846	Transcriptional regulator
FY147_24765	COG2814	Major facilitator Superfamily
FY147_24795	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY147_24810	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY147_24815	COG0583	DNA-binding transcription factor activity
FY147_24830	COG0071	Belongs to the small heat shock protein (HSP20) family
FY147_24880	COG3838	Conjugal transfer protein Trbc
FY147_24885	COG3702	type iv secretory pathway
FY147_24890	COG3451	type IV secretory pathway VirB4
FY147_24905	COG3704	protein secretion by the type IV secretion system
FY147_24915	COG3736	Type IV secretory pathway, component VirB8
FY147_24920	COG3504	Conjugal transfer protein
FY147_24925	COG2948	multi-organism process
FY147_24930	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY147_25030	COG3831	ATPase activity
FY147_25045	COG3505	Type IV secretory pathway VirD4
FY147_25070	COG0583	DNA-binding transcription factor activity
FY147_25110	COG0745	RESPONSE REGULATOR receiver
FY147_25150	COG3842	ATPase activity
FY147_25155	COG4208	sulfate ABC transporter
FY147_25160	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_25180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY147_25185	COG1942	4-Oxalocrotonate Tautomerase
FY147_25195	COG3971	2-oxopent-4-enoate hydratase activity
FY147_25205	COG1414	Transcriptional regulator
FY147_25215	COG1137	ATPase activity
FY147_25230	COG4177	L-phenylalanine transmembrane transporter activity
FY147_25250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY147_25255	COG1175	transmembrane transport
FY147_25260	COG0395	ABC-type sugar transport system, permease component
FY147_25270	COG0366	Alpha amylase catalytic
FY147_25275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY147_25280	COG1082	Xylose isomerase domain protein TIM barrel
FY147_25285	COG3842	ATPase activity
FY147_25295	COG1940	carbohydrate kinase activity
FY147_25300	COG0395	ABC-type sugar transport system, permease component
FY147_25310	COG2182	Extracellular solute-binding protein
FY147_25315	COG0673	inositol 2-dehydrogenase activity
FY147_25345	COG1126	abc transporter atp-binding protein
FY147_25350	COG0765	amino acid transport
FY147_25355	COG0765	amino acid transport
FY147_25365	COG4608	Belongs to the ABC transporter superfamily
FY147_25375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_25390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY147_25395	COG0583	DNA-binding transcription factor activity
FY147_25400	COG2423	ornithine cyclodeaminase activity
FY147_25410	COG1957	nucleoside hydrolase
FY147_25430	COG1335	isochorismatase
FY147_25435	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_25470	COG3547	Transposase (IS116 IS110 IS902 family)
FY147_25475	COG0251	oxidation-reduction process
FY147_25480	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY147_25535	COG4215	(ABC) transporter
FY147_25545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_25560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_25570	COG0747	negative chemotaxis
FY147_25590	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY147_25625	COG0477	Major facilitator Superfamily
FY147_25635	COG0395	ABC-type sugar transport system, permease component
FY147_25640	COG1175	transmembrane transport
FY147_25645	COG3842	ATPase activity
FY147_25655	COG4948	Mandelate Racemase Muconate Lactonizing
FY147_25665	COG1414	Transcriptional regulator
FY147_25670	COG0583	DNA-binding transcription factor activity
FY147_25705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY147_25715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY147_25740	COG1129	ABC transporter
FY147_25760	COG2272	Belongs to the type-B carboxylesterase lipase family
FY147_25770	COG2271	Major facilitator Superfamily
FY147_25775	COG0583	DNA-binding transcription factor activity
FY147_25795	COG1129	ABC transporter
FY147_25805	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_25810	COG1940	carbohydrate kinase activity
FY147_25835	COG2084	Dehydrogenase
FY147_25840	COG3622	Belongs to the hyi family
FY147_25845	COG3386	PFAM SMP-30 Gluconolaconase
FY147_25855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY147_25865	COG1012	belongs to the aldehyde dehydrogenase family
FY147_25905	COG1846	Transcriptional regulator
FY147_25925	COG3706	GGDEF domain
FY147_25940	COG0477	Major facilitator Superfamily
FY147_25945	COG1012	belongs to the aldehyde dehydrogenase family
FY147_25955	COG1024	Enoyl-CoA hydratase
FY147_25960	COG1960	acyl-CoA dehydrogenase activity
FY147_25970	COG1063	alcohol dehydrogenase
FY147_25985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY147_25990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY147_26005	COG3971	2-oxopent-4-enoate hydratase activity
FY147_26010	COG3485	protocatechuate 3,4-dioxygenase
FY147_26015	COG1802	Transcriptional regulator
FY147_26030	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_26075	COG2207	Transcriptional regulator
FY147_26155	COG1695	Transcriptional regulator
FY147_26165	COG0583	DNA-binding transcription factor activity
FY147_26170	COG1335	isochorismatase
FY147_26180	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_26185	COG0583	DNA-binding transcription factor activity
FY147_26190	COG1902	pentaerythritol trinitrate reductase activity
FY147_26195	COG0583	DNA-binding transcription factor activity
FY147_26240	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_26245	COG1335	isochorismatase
FY147_26255	COG1309	transcriptional regulator
FY147_26260	COG4604	ABC transporter, ATP-binding protein
FY147_26265	COG4605	iron ion homeostasis
FY147_26270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY147_26280	COG2132	Multicopper oxidase
FY147_26285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY147_26290	COG4771	TonB-dependent receptor
FY147_26325	COG1695	Transcriptional regulator
FY147_26360	COG2132	Multicopper oxidase
FY147_26395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY147_26415	COG1192	Involved in chromosome partitioning
FY147_26420	COG1475	DNA binding
FY147_26425	COG0640	Transcriptional regulator
FY147_26430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY147_26460	COG2211	Major facilitator Superfamily
FY147_26510	COG1051	belongs to the nudix hydrolase family
FY147_26550	COG1475	DNA binding
FY147_26575	COG2824	Alkylphosphonate utilization operon protein PhnA
FY147_26600	COG1280	lysine exporter protein (LysE YggA)
FY147_26615	COG5489	Protein of unknown function (DUF736)
FY147_26675	COG1879	ABC-type sugar transport system periplasmic component
FY147_26680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_26700	COG1280	lysine exporter protein (LysE YggA)
FY147_26785	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY147_26800	COG0747	negative chemotaxis
FY147_26805	COG0444	Belongs to the ABC transporter superfamily
FY147_26820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_26825	COG0584	glycerophosphoryl diester phosphodiesterase
FY147_26830	COG0483	inositol monophosphate 1-phosphatase activity
FY147_26895	COG3161	chorismate lyase activity
FY147_27045	COG3436	PFAM IS66 Orf2 family protein
FY147_27125	COG2222	sugar isomerase
FY147_27135	COG0006	proline dipeptidase activity
FY147_27155	COG1177	transmembrane transport
FY147_27160	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY147_27165	COG3842	ATPase activity
FY147_27195	COG3842	ATPase activity
FY147_27200	COG0006	proline dipeptidase activity
FY147_27220	COG0300	oxidoreductase activity
FY147_27225	COG0129	dihydroxy-acid dehydratase activity
FY147_27230	COG0667	Aldo Keto reductase
FY147_27240	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_27250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_27255	COG0601	transmembrane transport
FY147_27260	COG4172	Belongs to the ABC transporter superfamily
FY147_27270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY147_27305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_27340	COG3701	Conjugal transfer protein
FY147_27345	COG3846	protein secretion by the type IV secretion system
FY147_27355	COG5314	conjugation
FY147_27360	COG3451	type IV secretory pathway VirB4
FY147_27375	COG4962	Type ii secretion system protein e
FY147_27445	COG0583	DNA-binding transcription factor activity
FY147_27455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY147_27460	COG1116	anion transmembrane transporter activity
FY147_27465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY147_27475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_27480	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_27510	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY147_27515	COG1129	ABC transporter
FY147_27540	COG4172	Belongs to the ABC transporter superfamily
FY147_27545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_27550	COG0601	transmembrane transport
FY147_27560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_27565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_27570	COG0583	DNA-binding transcription factor activity
FY147_27580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY147_27595	COG1132	(ABC) transporter
FY147_27600	COG4172	Belongs to the ABC transporter superfamily
FY147_27610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY147_27625	COG0601	transmembrane transport
FY147_27645	COG1082	Xylose isomerase domain protein TIM barrel
FY147_27665	COG1475	DNA binding
FY147_27870	COG0583	DNA-binding transcription factor activity
FY147_27875	COG1126	abc transporter atp-binding protein
FY147_27880	COG0765	amino acid transport
FY147_27885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY147_27890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_27895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY147_28100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY147_28115	COG0469	pyruvate kinase activity
FY147_28125	COG0574	Belongs to the PEP-utilizing enzyme family
FY147_28125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY147_28135	COG1028	Short-chain dehydrogenase reductase Sdr
FY147_28150	COG1619	proteins homologs of microcin C7 resistance protein MccF
FY147_28160	COG2226	methyltransferase
FY147_28180	COG0495	leucyl-tRNA aminoacylation
FY147_28195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY147_28205	COG1132	(ABC) transporter
FY147_28235	COG1475	DNA binding