locus-tag	class	description
FY148_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY148_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY148_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY148_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY148_00025	COG1420	regulation of RNA biosynthetic process
FY148_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY148_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY148_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY148_00050	COG1137	ATPase activity
FY148_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY148_00065	COG0616	signal peptide processing
FY148_00070	COG0776	regulation of translation
FY148_00080	COG0116	Belongs to the methyltransferase superfamily
FY148_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY148_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY148_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY148_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY148_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY148_00115	COG0728	peptidoglycan biosynthetic process
FY148_00125	COG0180	Tryptophanyl-tRNA synthetase
FY148_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY148_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY148_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY148_00165	COG1702	phosphate starvation-inducible protein PhoH
FY148_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY148_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY148_00185	COG1396	sequence-specific DNA binding
FY148_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY148_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY148_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_00210	COG0242	peptide deformylase activity
FY148_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY148_00220	COG0101	tRNA pseudouridine synthase activity
FY148_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY148_00235	COG2171	N-acyltransferase activity
FY148_00245	COG0840	transmembrane signaling receptor activity
FY148_00250	COG1957	nucleoside hydrolase
FY148_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY148_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY148_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY148_00295	COG0706	membrane insertase activity
FY148_00300	COG0594	ribonuclease P activity
FY148_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY148_00310	COG0840	transmembrane signaling receptor activity
FY148_00325	COG2226	methyltransferase
FY148_00330	COG3842	ATPase activity
FY148_00335	COG1175	transmembrane transport
FY148_00340	COG0395	ABC-type sugar transport system, permease component
FY148_00355	COG0427	acetyl-CoA hydrolase
FY148_00365	COG3938	Belongs to the proline racemase family
FY148_00370	COG0418	dihydroorotase activity
FY148_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY148_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY148_00400	COG0166	Belongs to the GPI family
FY148_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY148_00410	COG3842	ATPase activity
FY148_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY148_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY148_00425	COG4774	siderophore transport
FY148_00470	COG2326	polyphosphate kinase activity
FY148_00475	COG5002	protein histidine kinase activity
FY148_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY148_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY148_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY148_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY148_00505	COG0745	RESPONSE REGULATOR receiver
FY148_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY148_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY148_00530	COG2967	ApaG domain
FY148_00545	COG0717	Belongs to the dCTP deaminase family
FY148_00555	COG0582	viral genome integration into host DNA
FY148_00580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY148_00630	COG1396	sequence-specific DNA binding
FY148_00645	COG1132	(ABC) transporter
FY148_00680	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY148_00685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY148_00735	COG0167	dihydroorotate dehydrogenase activity
FY148_00750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY148_00770	COG1959	2 iron, 2 sulfur cluster binding
FY148_00775	COG1201	RNA secondary structure unwinding
FY148_00805	COG1960	acyl-CoA dehydrogenase activity
FY148_00810	COG0183	Belongs to the thiolase family
FY148_00815	COG1024	Enoyl-CoA hydratase
FY148_00815	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY148_00835	COG1320	monovalent cation:proton antiporter activity
FY148_00840	COG2212	antiporter activity
FY148_00845	COG1863	multisubunit Na H antiporter MnhE subunit
FY148_00850	COG0651	ATP synthesis coupled electron transport
FY148_00855	COG1006	Multisubunit Na H antiporter MnhC subunit
FY148_00860	COG2111	Na H antiporter
FY148_00860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY148_00870	COG0840	transmembrane signaling receptor activity
FY148_00880	COG0745	RESPONSE REGULATOR receiver
FY148_00885	COG0643	Histidine kinase
FY148_00885	COG2198	Histidine kinase
FY148_00890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY148_00895	COG2201	protein-glutamate methylesterase activity
FY148_00900	COG0745	RESPONSE REGULATOR receiver
FY148_00905	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY148_00915	COG1766	The M ring may be actively involved in energy transduction
FY148_00920	COG2771	luxR family
FY148_00930	COG0840	transmembrane signaling receptor activity
FY148_00930	COG2972	Histidine kinase
FY148_00935	COG0784	Response regulator, receiver
FY148_00935	COG2198	Histidine kinase
FY148_00935	COG2205	protein histidine kinase activity
FY148_00940	COG1970	mechanosensitive ion channel activity
FY148_00945	COG0436	Aminotransferase
FY148_00960	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY148_00965	COG0424	maF-like protein
FY148_00970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY148_00980	COG5328	Belongs to the UPF0262 family
FY148_00985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY148_00995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY148_01015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY148_01025	COG1338	Plays a role in the flagellum-specific transport system
FY148_01035	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY148_01045	COG1706	bacterial-type flagellum-dependent cell motility
FY148_01050	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY148_01055	COG4786	Flagellar basal body rod
FY148_01060	COG1677	Flagellar hook-basal body complex protein FliE
FY148_01065	COG1558	bacterial-type flagellum-dependent cell motility
FY148_01070	COG1815	bacterial-type flagellum-dependent cell motility
FY148_01080	COG1157	protein secretion by the type III secretion system
FY148_01085	COG4786	Flagellar basal body rod
FY148_01095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY148_01100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY148_01105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY148_01110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY148_01115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY148_01140	COG1360	Flagellar Motor Protein
FY148_01165	COG1749	Flagellar hook protein flgE
FY148_01185	COG5443	negative regulation of bacterial-type flagellum assembly
FY148_01190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY148_01200	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY148_01240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY148_01245	COG1609	Transcriptional regulator
FY148_01250	COG1653	transport
FY148_01255	COG1175	transmembrane transport
FY148_01260	COG0395	ABC-type sugar transport system, permease component
FY148_01265	COG0366	Alpha amylase catalytic
FY148_01270	COG3842	ATPase activity
FY148_01285	COG0129	dihydroxy-acid dehydratase activity
FY148_01290	COG0363	glucosamine-6-phosphate deaminase activity
FY148_01295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY148_01305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_01315	COG2081	HI0933 family
FY148_01335	COG2224	Isocitrate lyase
FY148_01350	COG3842	ATPase activity
FY148_01355	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_01360	COG1177	transmembrane transport
FY148_01370	COG2205	protein histidine kinase activity
FY148_01380	COG0248	Ppx GppA phosphatase
FY148_01385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY148_01390	COG0477	Major facilitator Superfamily
FY148_01420	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY148_01425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY148_01435	COG0142	geranyltranstransferase activity
FY148_01460	COG0752	glycyl-tRNA synthetase alpha subunit
FY148_01470	COG1704	LemA family
FY148_01475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY148_01485	COG0751	glycine-tRNA ligase activity
FY148_01490	COG1683	Conserved Protein
FY148_01495	COG0840	transmembrane signaling receptor activity
FY148_01505	COG0151	Belongs to the GarS family
FY148_01510	COG2183	response to ionizing radiation
FY148_01515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY148_01525	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY148_01540	COG0583	DNA-binding transcription factor activity
FY148_01560	COG0306	phosphate transporter
FY148_01570	COG0561	phosphatase activity
FY148_01575	COG0438	transferase activity, transferring glycosyl groups
FY148_01580	COG2186	Transcriptional regulator
FY148_01595	COG0583	DNA-binding transcription factor activity
FY148_01600	COG0277	FAD linked oxidase domain protein
FY148_01605	COG0277	FAD linked oxidase domain protein
FY148_01610	COG0247	lactate metabolic process
FY148_01620	COG1376	ErfK ybiS ycfS ynhG family protein
FY148_01625	COG2818	Glycosylase
FY148_01635	COG2855	membrane
FY148_01640	COG0583	DNA-binding transcription factor activity
FY148_01670	COG0124	histidyl-tRNA synthetase
FY148_01680	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY148_01685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY148_01690	COG2259	Doxx family
FY148_01700	COG0459	protein refolding
FY148_01705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY148_01715	COG0196	riboflavin kinase activity
FY148_01720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY148_01730	COG0590	tRNA wobble adenosine to inosine editing
FY148_01735	COG1187	pseudouridine synthase activity
FY148_01740	COG0742	ribosomal rna small subunit methyltransferase
FY148_01745	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY148_01755	COG0312	modulator of DNA gyrase
FY148_01760	COG0483	inositol monophosphate 1-phosphatase activity
FY148_01770	COG1519	Transferase
FY148_01780	COG1663	tetraacyldisaccharide 4'-kinase activity
FY148_01790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY148_01795	COG0745	RESPONSE REGULATOR receiver
FY148_01800	COG5001	Diguanylate cyclase
FY148_01800	COG3300	MHYT domain
FY148_01805	COG3386	PFAM SMP-30 Gluconolaconase
FY148_01810	COG0800	Aldolase
FY148_01815	COG3734	2-keto-3-deoxy-galactonokinase
FY148_01820	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_01825	COG1414	Transcriptional regulator
FY148_01830	COG2197	response regulator
FY148_01845	COG0598	Magnesium transport protein CorA
FY148_01850	COG3158	transport of potassium into the cell
FY148_01865	COG0356	it plays a direct role in the translocation of protons across the membrane
FY148_01875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY148_01880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY148_01895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY148_01915	COG0009	L-threonylcarbamoyladenylate synthase
FY148_01925	COG4638	Rieske (2fe-2S)
FY148_01950	COG1960	acyl-CoA dehydrogenase activity
FY148_01965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY148_01970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY148_01975	COG0840	transmembrane signaling receptor activity
FY148_01985	COG1522	sequence-specific DNA binding
FY148_02010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY148_02015	COG1741	Belongs to the pirin family
FY148_02020	COG1722	exodeoxyribonuclease VII activity
FY148_02025	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY148_02030	COG1268	BioY protein
FY148_02035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY148_02040	COG1122	ATPase activity
FY148_02045	COG3214	Protein conserved in bacteria
FY148_02050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY148_02050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY148_02055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY148_02070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY148_02085	COG0259	pyridoxamine-phosphate oxidase activity
FY148_02115	COG0312	modulator of DNA gyrase
FY148_02130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY148_02135	COG0109	protoheme IX farnesyltransferase activity
FY148_02140	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY148_02155	COG3346	SURF1 family
FY148_02160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY148_02165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY148_02170	COG0328	RNA-DNA hybrid ribonuclease activity
FY148_02180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY148_02180	COG0678	peroxiredoxin activity
FY148_02190	COG1678	Uncharacterized ACR, COG1678
FY148_02195	COG3237	CsbD-like
FY148_02205	COG5001	Diguanylate cyclase
FY148_02205	COG3300	MHYT domain
FY148_02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY148_02215	COG0612	Peptidase, M16
FY148_02240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY148_02245	COG1802	Transcriptional regulator
FY148_02260	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY148_02265	COG3609	addiction module antidote protein, CC2985 family
FY148_02270	COG3668	Plasmid stabilization system
FY148_02280	COG1194	a g-specific adenine glycosylase
FY148_02295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY148_02300	COG1196	nuclear chromosome segregation
FY148_02305	COG2514	catechol 2,3-dioxygenase activity
FY148_02310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY148_02310	COG0574	Belongs to the PEP-utilizing enzyme family
FY148_02325	COG1823	symporter activity
FY148_02355	COG0579	oxidoreductase
FY148_02375	COG2895	sulfate adenylyltransferase (ATP) activity
FY148_02380	COG0175	sulfate reduction
FY148_02385	COG0175	sulfate reduction
FY148_02390	COG1959	2 iron, 2 sulfur cluster binding
FY148_02395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY148_02400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY148_02405	COG4208	sulfate ABC transporter
FY148_02410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY148_02420	COG2203	Gaf domain
FY148_02420	COG2200	EAL domain
FY148_02420	COG2199	diguanylate cyclase activity
FY148_02430	COG1309	transcriptional regulator
FY148_02435	COG1012	belongs to the aldehyde dehydrogenase family
FY148_02440	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY148_02470	COG0625	glutathione transferase activity
FY148_02480	COG0477	Major facilitator Superfamily
FY148_02490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY148_02490	COG1793	dna ligase
FY148_02510	COG1376	ErfK ybiS ycfS ynhG family protein
FY148_02515	COG1376	ErfK ybiS ycfS ynhG family protein
FY148_02520	COG1846	Transcriptional regulator
FY148_02525	COG1764	response to oxidative stress
FY148_02540	COG0488	(ABC) transporter
FY148_02575	COG4221	oxidoreductase activity
FY148_02590	COG0433	COG0433 Predicted ATPase
FY148_02600	COG1733	regulation of RNA biosynthetic process
FY148_02605	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY148_02620	COG0656	L-ascorbic acid biosynthetic process
FY148_02625	COG3781	membrane
FY148_02630	COG2378	regulation of single-species biofilm formation
FY148_02640	COG4106	trans-aconitate 2-methyltransferase activity
FY148_02645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY148_02650	COG0840	transmembrane signaling receptor activity
FY148_02655	COG0583	DNA-binding transcription factor activity
FY148_02670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY148_02690	COG3909	cytochrome
FY148_02695	COG2010	Cytochrome c
FY148_02725	COG0789	Transcriptional regulator
FY148_02750	COG0517	IMP dehydrogenase activity
FY148_02750	COG4175	Glycine betaine
FY148_02755	COG4176	ABC-type proline glycine betaine transport system permease component
FY148_02780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_02790	COG2169	Transcriptional regulator
FY148_02790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY148_02800	COG2514	catechol 2,3-dioxygenase activity
FY148_02820	COG1272	protein, Hemolysin III
FY148_02830	COG1280	lysine exporter protein (LysE YggA)
FY148_02835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY148_02840	COG2111	Na H antiporter
FY148_02840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY148_02845	COG2111	Na H antiporter
FY148_02850	COG1006	Multisubunit Na H antiporter MnhC subunit
FY148_02855	COG0651	ATP synthesis coupled electron transport
FY148_02860	COG1863	multisubunit Na H antiporter MnhE subunit
FY148_02865	COG2212	antiporter activity
FY148_02870	COG1320	monovalent cation:proton antiporter activity
FY148_02875	COG4957	zinc ion binding
FY148_02890	COG2166	iron-sulfur cluster assembly
FY148_02900	COG2205	protein histidine kinase activity
FY148_02945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY148_02950	COG2983	Belongs to the UPF0260 family
FY148_02960	COG3041	Addiction module toxin RelE StbE family
FY148_02965	COG3077	Addiction module antitoxin, RelB DinJ family
FY148_03005	COG2814	Major facilitator Superfamily
FY148_03010	COG1621	beta-fructofuranosidase activity
FY148_03015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY148_03065	COG4695	Portal protein
FY148_03170	COG4235	cytochrome complex assembly
FY148_03175	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY148_03180	COG1138	Cytochrome C-type biogenesis protein
FY148_03185	COG3088	subunit of a heme lyase
FY148_03190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY148_03195	COG0745	RESPONSE REGULATOR receiver
FY148_03205	COG3011	Protein conserved in bacteria
FY148_03210	COG3713	MltA-interacting MipA family protein
FY148_03215	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY148_03220	COG2202	Pas domain
FY148_03220	COG2205	protein histidine kinase activity
FY148_03230	COG0308	aminopeptidase N
FY148_03235	COG0697	spore germination
FY148_03250	COG0443	Heat shock 70 kDa protein
FY148_03285	COG0604	alcohol dehydrogenase
FY148_03290	COG1733	regulation of RNA biosynthetic process
FY148_03295	COG1968	undecaprenyl-diphosphatase activity
FY148_03300	COG2239	Acts as a magnesium transporter
FY148_03305	COG2814	Major facilitator Superfamily
FY148_03330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY148_03355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY148_03395	COG0741	lytic transglycosylase activity
FY148_03400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_03405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY148_03410	COG0840	transmembrane signaling receptor activity
FY148_03420	COG1758	RNA polymerase activity
FY148_03440	COG0736	holo-[acyl-carrier-protein] synthase activity
FY148_03445	COG0681	Belongs to the peptidase S26 family
FY148_03450	COG0571	ribonuclease III activity
FY148_03455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY148_03465	COG0784	Response regulator, receiver
FY148_03470	COG1381	Involved in DNA repair and RecF pathway recombination
FY148_03480	COG2226	methyltransferase
FY148_03490	COG1418	mRNA catabolic process
FY148_03500	COG0346	lactoylglutathione lyase activity
FY148_03515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_03520	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY148_03525	COG0668	transmembrane transport
FY148_03535	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY148_03565	COG1742	UPF0060 membrane protein
FY148_03580	COG1183	phosphatidylcholine synthase activity
FY148_03585	COG0688	phosphatidylethanolamine metabolic process
FY148_03590	COG5265	(ABC) transporter
FY148_03630	COG2852	Protein conserved in bacteria
FY148_03635	COG0215	cysteine-tRNA ligase activity
FY148_03640	COG4221	oxidoreductase activity
FY148_03645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY148_03650	COG1286	toxin biosynthetic process
FY148_03670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY148_03680	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY148_03690	COG0305	Participates in initiation and elongation during chromosome replication
FY148_03710	COG0359	binds to the 23S rRNA
FY148_03720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY148_03725	COG0360	Binds together with S18 to 16S ribosomal RNA
FY148_03735	COG0667	Aldo Keto reductase
FY148_03740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY148_03750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY148_03755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY148_03765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY148_03770	COG1561	YicC-like family, N-terminal region
FY148_03775	COG0194	GDP metabolic process
FY148_03790	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY148_03795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY148_03805	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY148_03820	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY148_03840	COG5001	Diguanylate cyclase
FY148_03840	COG2203	Gaf domain
FY148_03840	COG3706	GGDEF domain
FY148_03840	COG4251	negative regulation of phosphorylation
FY148_03845	COG5001	Diguanylate cyclase
FY148_03845	COG3300	MHYT domain
FY148_03850	COG4191	Histidine kinase
FY148_03855	COG4566	intracellular signal transduction
FY148_03865	COG0488	(ABC) transporter
FY148_03870	COG3706	GGDEF domain
FY148_03880	COG0105	UTP biosynthetic process
FY148_03900	COG0314	molybdopterin synthase activity
FY148_03910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY148_03915	COG0322	excinuclease ABC activity
FY148_03920	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_03945	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY148_03950	COG0243	molybdopterin cofactor binding
FY148_03975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY148_03980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY148_03985	COG2226	methyltransferase
FY148_03990	COG0628	permease
FY148_04000	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY148_04005	COG0248	Ppx GppA phosphatase
FY148_04030	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY148_04040	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY148_04045	COG0477	Major facilitator Superfamily
FY148_04050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY148_04060	COG0840	transmembrane signaling receptor activity
FY148_04065	COG0659	secondary active sulfate transmembrane transporter activity
FY148_04075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY148_04080	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY148_04090	COG0113	porphobilinogen synthase activity
FY148_04110	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY148_04115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY148_04120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY148_04120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY148_04130	COG1280	lysine exporter protein (LysE YggA)
FY148_04135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY148_04140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY148_04145	COG2814	Major facilitator Superfamily
FY148_04150	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY148_04170	COG0416	fatty acid biosynthetic process
FY148_04175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY148_04180	COG0776	regulation of translation
FY148_04215	COG0601	transmembrane transport
FY148_04220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_04225	COG0444	Belongs to the ABC transporter superfamily
FY148_04235	COG0747	negative chemotaxis
FY148_04245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY148_04250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY148_04265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY148_04270	COG0583	DNA-binding transcription factor activity
FY148_04275	COG0737	Belongs to the 5'-nucleotidase family
FY148_04295	COG2897	thiosulfate sulfurtransferase activity
FY148_04310	COG0415	Belongs to the DNA photolyase family
FY148_04320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY148_04350	COG3932	Exopolysaccharide synthesis, ExoD
FY148_04355	COG1238	metal cluster binding
FY148_04430	COG1612	heme a metabolic process
FY148_04440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY148_04445	COG0010	Belongs to the arginase family
FY148_04450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY148_04455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY148_04465	COG1832	CoA-binding protein
FY148_04490	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_04495	COG2124	cytochrome p450
FY148_04500	COG2199	diguanylate cyclase activity
FY148_04505	COG0740	serine-type endopeptidase activity
FY148_04510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY148_04515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY148_04525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY148_04550	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY148_04555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY148_04560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY148_04570	COG0649	NAD binding
FY148_04580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY148_04585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY148_04595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY148_04600	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY148_04610	COG0713	ATP synthesis coupled electron transport
FY148_04625	COG1007	ATP synthesis coupled electron transport
FY148_04630	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY148_04630	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY148_04645	COG0442	prolyl-tRNA aminoacylation
FY148_04655	COG1136	(ABC) transporter
FY148_04670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY148_04690	COG0784	Response regulator, receiver
FY148_04700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY148_04705	COG0477	Major facilitator Superfamily
FY148_04720	COG0557	exoribonuclease II activity
FY148_04725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY148_04735	COG0758	DNA mediated transformation
FY148_04740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY148_04750	COG0540	Belongs to the ATCase OTCase family
FY148_04765	COG1960	acyl-CoA dehydrogenase activity
FY148_04770	COG0456	acetyltransferase
FY148_04790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY148_04795	COG2824	Alkylphosphonate utilization operon protein PhnA
FY148_04800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY148_04805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY148_04810	COG0154	amidase activity
FY148_04815	COG0456	acetyltransferase
FY148_04820	COG3811	Belongs to the UPF0386 family
FY148_04835	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY148_04845	COG0456	acetyltransferase
FY148_04865	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY148_04870	COG0439	Biotin carboxylase
FY148_04875	COG0511	ligase activity, forming carbon-carbon bonds
FY148_04880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY148_04890	COG0436	Aminotransferase
FY148_04910	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_04915	COG1530	ribonuclease E activity
FY148_04925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY148_04945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY148_04950	COG0384	phenazine biosynthesis protein PhzF
FY148_04970	COG0633	Ferredoxin
FY148_04985	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY148_04990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY148_05000	COG3768	UPF0283 membrane protein
FY148_05005	COG3106	COG3106 Predicted ATPase
FY148_05035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY148_05070	COG0537	adenosine 5'-monophosphoramidase activity
FY148_05095	COG0052	Belongs to the universal ribosomal protein uS2 family
FY148_05100	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY148_05105	COG0528	UMP kinase activity
FY148_05110	COG0233	cytoplasmic translational termination
FY148_05115	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY148_05125	COG0750	zinc metalloprotease
FY148_05130	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY148_05135	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY148_05140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY148_05145	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY148_05150	COG3494	Protein of unknown function (DUF1009)
FY148_05155	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY148_05160	COG2186	Transcriptional regulator
FY148_05170	COG0765	amino acid transport
FY148_05175	COG0765	amino acid transport
FY148_05185	COG0372	Belongs to the citrate synthase family
FY148_05200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY148_05210	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY148_05215	COG0148	phosphopyruvate hydratase activity
FY148_05225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY148_05230	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY148_05230	COG0022	dehydrogenase e1 component
FY148_05235	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY148_05245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY148_05255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY148_05260	COG0697	spore germination
FY148_05275	COG2867	negative regulation of translational initiation
FY148_05280	COG1058	Belongs to the CinA family
FY148_05280	COG1546	Belongs to the CinA family
FY148_05285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY148_05285	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY148_05295	COG3852	Histidine kinase
FY148_05300	COG2204	response regulator
FY148_05305	COG5000	phosphorelay sensor kinase activity
FY148_05310	COG2204	response regulator
FY148_05315	COG0569	domain protein
FY148_05320	COG1923	regulation of RNA biosynthetic process
FY148_05325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY148_05330	COG3956	TIGRFAM MazG family protein
FY148_05340	COG1648	precorrin-2 dehydrogenase activity
FY148_05340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY148_05380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY148_05380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY148_05385	COG0509	glycine decarboxylation via glycine cleavage system
FY148_05390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY148_05415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY148_05420	COG0564	pseudouridine synthase activity
FY148_05440	COG0251	oxidation-reduction process
FY148_05445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY148_05455	COG1671	Belongs to the UPF0178 family
FY148_05470	COG0450	alkyl hydroperoxide reductase
FY148_05475	COG0625	glutathione transferase activity
FY148_05485	COG2801	Transposase and inactivated derivatives
FY148_05490	COG0431	NADPH-dependent FMN reductase
FY148_05500	COG0798	PFAM Bile acid sodium symporter
FY148_05505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY148_05520	COG0321	lipoyl(octanoyl) transferase activity
FY148_05520	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY148_05525	COG0084	hydrolase, TatD family'
FY148_05530	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY148_05540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY148_05595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY148_05600	COG2095	MarC family integral membrane protein
FY148_05605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY148_05605	COG0517	IMP dehydrogenase activity
FY148_05605	COG0617	tRNA 3'-terminal CCA addition
FY148_05615	COG0629	single-stranded DNA binding
FY148_05620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY148_05630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY148_05635	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY148_05650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY148_05655	COG1121	(ABC) transporter
FY148_05675	COG0667	Aldo Keto reductase
FY148_05685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY148_05770	COG2239	Acts as a magnesium transporter
FY148_05775	COG0243	molybdopterin cofactor binding
FY148_05785	COG0242	peptide deformylase activity
FY148_05795	COG2205	protein histidine kinase activity
FY148_05795	COG2202	Pas domain
FY148_05805	COG0321	lipoyl(octanoyl) transferase activity
FY148_05810	COG1064	alcohol dehydrogenase
FY148_05840	COG1862	Preprotein translocase
FY148_05860	COG2124	cytochrome p450
FY148_05875	COG0596	Alpha beta hydrolase
FY148_05890	COG0626	cystathionine gamma-synthase activity
FY148_05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_05900	COG4597	amino acid ABC transporter
FY148_05905	COG0765	amino acid transport
FY148_05910	COG1126	abc transporter atp-binding protein
FY148_05920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY148_05935	COG0436	Aminotransferase
FY148_05965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY148_05975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY148_05980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY148_05985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY148_06000	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY148_06005	COG1489	DNA binding
FY148_06010	COG0024	Methionine aminopeptidase
FY148_06015	COG2003	Belongs to the UPF0758 family
FY148_06030	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY148_06055	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY148_06060	COG0546	phosphoglycolate phosphatase activity
FY148_06070	COG0114	fumarate hydratase activity
FY148_06080	COG0504	CTP synthase activity
FY148_06090	COG0149	triose-phosphate isomerase activity
FY148_06100	COG0187	DNA topoisomerase II activity
FY148_06110	COG0740	serine-type endopeptidase activity
FY148_06120	COG0640	Transcriptional regulator
FY148_06125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY148_06130	COG0745	RESPONSE REGULATOR receiver
FY148_06145	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY148_06145	COG3264	Mechanosensitive ion channel
FY148_06205	COG1127	ABC transporter
FY148_06210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY148_06215	COG4948	Mandelate Racemase Muconate Lactonizing
FY148_06225	COG0280	phosphate acetyltransferase
FY148_06225	COG0281	malic enzyme
FY148_06235	COG0778	Nitroreductase
FY148_06240	COG0823	Involved in the tonB-independent uptake of proteins
FY148_06255	COG1368	sulfuric ester hydrolase activity
FY148_06275	COG3265	gluconokinase activity
FY148_06280	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY148_06300	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY148_06320	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY148_06335	COG0318	PFAM AMP-dependent synthetase and ligase
FY148_06345	COG0512	Glutamine amidotransferase of anthranilate synthase
FY148_06345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY148_06350	COG0343	queuine tRNA-ribosyltransferase activity
FY148_06355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY148_06370	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY148_06385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY148_06390	COG0134	indole-3-glycerol-phosphate synthase activity
FY148_06395	COG0315	cyclic pyranopterin monophosphate synthase activity
FY148_06400	COG0303	'Molybdopterin
FY148_06405	COG3706	GGDEF domain
FY148_06415	COG0475	glutathione-regulated potassium exporter activity
FY148_06415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY148_06425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY148_06435	COG2814	Major facilitator Superfamily
FY148_06440	COG0746	molybdenum cofactor guanylyltransferase activity
FY148_06445	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY148_06450	COG0739	heme binding
FY148_06455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY148_06460	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY148_06465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY148_06470	COG0805	protein transport
FY148_06475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY148_06480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY148_06485	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY148_06490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY148_06495	COG1472	Belongs to the glycosyl hydrolase 3 family
FY148_06505	COG0018	arginyl-trna synthetase
FY148_06510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY148_06535	COG0525	valine-tRNA ligase activity
FY148_06545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY148_06790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY148_06800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FY148_07005	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY148_07010	COG1058	Belongs to the CinA family
FY148_07010	COG1546	Belongs to the CinA family
FY148_07015	COG0589	response to stress
FY148_07020	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY148_07030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY148_07090	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY148_07110	COG0515	serine threonine protein kinase
FY148_07110	COG2815	serine threonine protein kinase
FY148_07130	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_07135	COG0583	DNA-binding transcription factor activity
FY148_07140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY148_07205	COG0640	Transcriptional regulator
FY148_07210	COG1914	H( )-stimulated, divalent metal cation uptake system
FY148_07220	COG1132	(ABC) transporter
FY148_07225	COG0628	permease
FY148_07260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY148_07270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY148_07280	COG0302	gtp cyclohydrolase
FY148_07285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY148_07290	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY148_07300	COG0516	GMP reductase activity
FY148_07300	COG0517	IMP dehydrogenase activity
FY148_07335	COG1760	l-serine dehydratase
FY148_07375	COG0583	DNA-binding transcription factor activity
FY148_07390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY148_07390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY148_07400	COG0347	Belongs to the P(II) protein family
FY148_07405	COG0174	glutamine synthetase
FY148_07435	COG0697	spore germination
FY148_07445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY148_07455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY148_07485	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY148_07490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY148_07495	COG2186	Transcriptional regulator
FY148_07505	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY148_07510	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY148_07515	COG3845	ABC transporter
FY148_07520	COG1183	phosphatidylcholine synthase activity
FY148_07525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY148_07530	COG0679	Auxin Efflux Carrier
FY148_07535	COG0785	Cytochrome C biogenesis protein
FY148_07555	COG1278	Cold shock
FY148_07605	COG0577	efflux transmembrane transporter activity
FY148_07605	COG1136	(ABC) transporter
FY148_07610	COG1136	(ABC) transporter
FY148_07610	COG0577	efflux transmembrane transporter activity
FY148_07635	COG2151	metal-sulfur cluster biosynthetic enzyme
FY148_07640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY148_07645	COG0719	Fe-S assembly protein
FY148_07650	COG0396	ATPase activity
FY148_07655	COG0719	Fe-S assembly protein
FY148_07660	COG1104	cysteine desulfurase activity
FY148_07665	COG2945	thiolester hydrolase activity
FY148_07670	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY148_07675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY148_07685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY148_07690	COG2833	Protein of unknown function (DUF455)
FY148_07695	COG0739	heme binding
FY148_07700	COG0513	Belongs to the DEAD box helicase family
FY148_07725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY148_07735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY148_07740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY148_07745	COG0047	phosphoribosylformylglycinamidine synthase activity
FY148_07760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY148_07765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY148_07785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY148_07790	COG2814	Major facilitator Superfamily
FY148_07930	COG4373	Mu-like prophage FluMu protein gp28
FY148_07935	COG4383	Mu-like prophage protein gp29
FY148_07960	COG4397	Mu-like prophage major head subunit gpT
FY148_07980	COG4387	Mu-like prophage protein GP36
FY148_08035	COG3299	homolog of phage Mu protein gp47
FY148_08060	COG0483	inositol monophosphate 1-phosphatase activity
FY148_08065	COG0483	inositol monophosphate 1-phosphatase activity
FY148_08070	COG0037	tRNA processing
FY148_08075	COG2066	Belongs to the glutaminase family
FY148_08080	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY148_08085	COG0861	Integral membrane protein TerC family
FY148_08100	COG1280	lysine exporter protein (LysE YggA)
FY148_08110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY148_08115	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY148_08125	COG0538	isocitrate dehydrogenase activity
FY148_08135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY148_08140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY148_08145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_08150	COG2313	pseudouridylate synthase activity
FY148_08160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_08165	COG4215	(ABC) transporter
FY148_08175	COG5425	PFAM Usg family protein
FY148_08185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY148_08190	COG1522	sequence-specific DNA binding
FY148_08195	COG1573	uracil-dna glycosylase
FY148_08205	COG2205	protein histidine kinase activity
FY148_08205	COG2202	Pas domain
FY148_08215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY148_08220	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY148_08235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY148_08240	COG0842	Transport permease protein
FY148_08245	COG1131	(ABC) transporter
FY148_08250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY148_08250	COG0730	response to heat
FY148_08270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY148_08275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY148_08295	COG0129	dihydroxy-acid dehydratase activity
FY148_08300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY148_08305	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY148_08315	COG3739	integral membrane protein
FY148_08325	COG0203	ribosomal protein L17
FY148_08330	COG0202	RNA polymerase activity
FY148_08335	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY148_08340	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY148_08345	COG0563	adenylate kinase activity
FY148_08350	COG0201	protein transport
FY148_08355	COG0200	Binds to the 23S rRNA
FY148_08360	COG1841	ribosomal large subunit assembly
FY148_08365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY148_08370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY148_08375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY148_08380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY148_08385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY148_08390	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY148_08395	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY148_08400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY148_08405	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY148_08410	COG0255	Belongs to the universal ribosomal protein uL29 family
FY148_08415	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY148_08420	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY148_08425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY148_08430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY148_08435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY148_08440	COG0089	rRNA binding
FY148_08445	COG0088	Forms part of the polypeptide exit tunnel
FY148_08450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY148_08455	COG0051	transcription antitermination factor activity, RNA binding
FY148_08460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY148_08465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY148_08470	COG0049	tRNA binding
FY148_08475	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY148_08495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY148_08500	COG0085	RNA polymerase activity
FY148_08505	COG0222	ribosome binding
FY148_08510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY148_08515	COG0081	regulation of translation
FY148_08520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY148_08530	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY148_08540	COG1086	Polysaccharide biosynthesis protein
FY148_08545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY148_08550	COG0861	Integral membrane protein TerC family
FY148_08555	COG3895	Periplasmic Protein
FY148_08575	COG1132	(ABC) transporter
FY148_08580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY148_08600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY148_08635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_08635	COG0784	Response regulator, receiver
FY148_08635	COG2205	protein histidine kinase activity
FY148_08635	COG2198	Histidine kinase
FY148_08640	COG0784	Response regulator, receiver
FY148_08645	COG2202	Pas domain
FY148_08645	COG3920	Histidine kinase
FY148_08650	COG0784	Response regulator, receiver
FY148_08655	COG4251	negative regulation of phosphorylation
FY148_08670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY148_08675	COG1607	acyl-coa hydrolase
FY148_08695	COG2910	NAD(P)H-binding
FY148_08700	COG1733	regulation of RNA biosynthetic process
FY148_08715	COG0556	nucleotide-excision repair
FY148_08725	COG2382	esterase
FY148_08745	COG0484	heat shock protein binding
FY148_08765	COG3706	GGDEF domain
FY148_08785	COG1840	ABC-type Fe3 transport system, periplasmic component
FY148_08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY148_08805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY148_08815	COG2207	Transcriptional regulator
FY148_08820	COG1064	alcohol dehydrogenase
FY148_08825	COG1252	NADH dehydrogenase
FY148_08830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY148_08840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY148_08875	COG0656	L-ascorbic acid biosynthetic process
FY148_08890	COG0440	acetolactate synthase activity
FY148_08895	COG0028	Belongs to the TPP enzyme family
FY148_08910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY148_08915	COG0560	Phosphoserine phosphatase
FY148_08915	COG3830	Belongs to the UPF0237 family
FY148_08935	COG0330	HflC and HflK could
FY148_08940	COG0330	HflC and HflK could
FY148_08950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY148_08985	COG0277	FAD linked oxidase domain protein
FY148_08990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY148_09030	COG1335	isochorismatase
FY148_09055	COG2264	protein methyltransferase activity
FY148_09060	COG1999	signal sequence binding
FY148_09070	COG0835	chemotaxis
FY148_09080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY148_09085	COG0583	DNA-binding transcription factor activity
FY148_09095	COG1247	-acetyltransferase
FY148_09105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY148_09110	COG0497	DNA recombination
FY148_09115	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY148_09125	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY148_09130	COG0849	cell division
FY148_09135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY148_09140	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY148_09145	COG0477	Major facilitator Superfamily
FY148_09150	COG5001	Diguanylate cyclase
FY148_09155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY148_09160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY148_09165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY148_09175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY148_09180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY148_09190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY148_09205	COG0275	rRNA processing
FY148_09210	COG2001	Belongs to the MraZ family
FY148_09235	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY148_09265	COG4106	trans-aconitate 2-methyltransferase activity
FY148_09285	COG2226	methyltransferase
FY148_09295	COG2267	carboxylic ester hydrolase activity
FY148_09300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY148_09315	COG0251	oxidation-reduction process
FY148_09330	COG1376	ErfK ybiS ycfS ynhG family protein
FY148_09335	COG2814	Major facilitator Superfamily
FY148_09365	COG1012	belongs to the aldehyde dehydrogenase family
FY148_09370	COG0174	glutamine synthetase
FY148_09375	COG0531	amino acid
FY148_09385	COG1737	Transcriptional regulator
FY148_09390	COG2182	Extracellular solute-binding protein
FY148_09405	COG3842	ATPase activity
FY148_09470	COG2968	Membrane
FY148_09480	COG0432	Pfam Uncharacterised protein family UPF0047
FY148_09495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY148_09500	COG0358	DNA primase activity
FY148_09520	COG0505	Belongs to the CarA family
FY148_09525	COG0534	Mate efflux family protein
FY148_09540	COG2321	neutral zinc metallopeptidase
FY148_09555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY148_09565	COG3706	GGDEF domain
FY148_09580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY148_09590	COG1522	sequence-specific DNA binding
FY148_09595	COG0492	ferredoxin-NADP+ reductase activity
FY148_09600	COG0583	DNA-binding transcription factor activity
FY148_09610	COG1902	pentaerythritol trinitrate reductase activity
FY148_09635	COG0387	Pfam Sodium calcium exchanger
FY148_09640	COG0436	Aminotransferase
FY148_09645	COG2200	EAL domain
FY148_09645	COG2199	diguanylate cyclase activity
FY148_09660	COG1278	Cold shock
FY148_09665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY148_09675	COG1846	Transcriptional regulator
FY148_09680	COG0745	RESPONSE REGULATOR receiver
FY148_09690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY148_09710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY148_09720	COG1496	oxidoreductase activity
FY148_09735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY148_09745	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY148_09760	COG0840	transmembrane signaling receptor activity
FY148_09765	COG1012	belongs to the aldehyde dehydrogenase family
FY148_09770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY148_09775	COG3300	MHYT domain
FY148_09775	COG5001	Diguanylate cyclase
FY148_09780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY148_09785	COG5001	Diguanylate cyclase
FY148_09795	COG0193	aminoacyl-tRNA hydrolase activity
FY148_09805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY148_09830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY148_09840	COG2857	Cytochrome c1
FY148_09840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY148_09860	COG1132	(ABC) transporter
FY148_09865	COG1132	(ABC) transporter
FY148_09875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY148_09890	COG0408	coproporphyrinogen oxidase activity
FY148_09905	COG0617	tRNA 3'-terminal CCA addition
FY148_09920	COG0714	Associated with various cellular activities
FY148_09940	COG0454	-acetyltransferase
FY148_09955	COG0477	Major facilitator Superfamily
FY148_09965	COG0435	Glutathione S-transferase
FY148_09970	COG0494	nUDIX hydrolase
FY148_09980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY148_09985	COG3135	benzoate transporter
FY148_10010	COG0740	serine-type endopeptidase activity
FY148_10025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY148_10030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY148_10055	COG4175	Glycine betaine
FY148_10075	COG1435	thymidine kinase activity
FY148_10100	COG1629	transport
FY148_10100	COG4771	TonB-dependent receptor
FY148_10110	COG0512	Glutamine amidotransferase of anthranilate synthase
FY148_10110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY148_10125	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY148_10135	COG0366	Alpha amylase catalytic
FY148_10140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_10160	COG1160	GTP binding
FY148_10180	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY148_10190	COG0024	Methionine aminopeptidase
FY148_10200	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_10220	COG0583	DNA-binding transcription factor activity
FY148_10235	COG0402	S-adenosylhomocysteine deaminase activity
FY148_10255	COG1309	transcriptional regulator
FY148_10260	COG1686	Belongs to the peptidase S11 family
FY148_10270	COG2351	hydroxyisourate hydrolase activity
FY148_10275	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY148_10290	COG3648	Uricase
FY148_10290	COG3195	allantoin biosynthetic process
FY148_10300	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY148_10310	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY148_10310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_10320	COG0513	Belongs to the DEAD box helicase family
FY148_10330	COG2259	Doxx family
FY148_10335	COG1376	ErfK ybiS ycfS ynhG family protein
FY148_10345	COG2308	Evidence 4 Homologs of previously reported genes of
FY148_10355	COG1305	Transglutaminase-like
FY148_10380	COG4214	carbohydrate transport
FY148_10390	COG4213	ABC transporter substrate-binding protein
FY148_10455	COG2948	multi-organism process
FY148_10465	COG3701	Conjugal transfer protein
FY148_10470	COG3846	protein secretion by the type IV secretion system
FY148_10485	COG3451	type IV secretory pathway VirB4
FY148_10495	COG3838	Conjugal transfer protein Trbc
FY148_10500	COG4962	Type ii secretion system protein e
FY148_10505	COG0583	DNA-binding transcription factor activity
FY148_10525	COG4172	Belongs to the ABC transporter superfamily
FY148_10535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_10550	COG0251	oxidation-reduction process
FY148_10555	COG1609	Transcriptional regulator
FY148_10590	COG1196	nuclear chromosome segregation
FY148_10590	COG0741	lytic transglycosylase activity
FY148_10590	COG0739	heme binding
FY148_10600	COG4959	Type IV secretory pathway protease TraF
FY148_10650	COG5489	Protein of unknown function (DUF736)
FY148_10690	COG4372	Transposase
FY148_10695	COG3436	PFAM IS66 Orf2 family protein
FY148_10700	COG2963	transposase activity
FY148_10735	COG2972	Histidine kinase
FY148_10735	COG0840	transmembrane signaling receptor activity
FY148_10750	COG0646	methionine synthase
FY148_10750	COG1410	methionine synthase
FY148_10795	COG1215	transferase activity, transferring glycosyl groups
FY148_10825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY148_10840	COG2346	COG2346, Truncated hemoglobins
FY148_10860	COG1309	transcriptional regulator
FY148_10875	COG0494	nUDIX hydrolase
FY148_10885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_10890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_10920	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY148_10925	COG0830	nickel cation binding
FY148_10930	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY148_10945	COG0804	urea catabolic process
FY148_10950	COG1442	glycosyl transferase family 8
FY148_10955	COG3755	Protein conserved in bacteria
FY148_10965	COG0832	Belongs to the urease beta subunit family
FY148_10970	COG3813	Protein conserved in bacteria
FY148_10975	COG0831	urea catabolic process
FY148_10980	COG0829	nickel cation binding
FY148_11005	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY148_11020	COG0174	glutamine synthetase
FY148_11025	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_11030	COG5002	protein histidine kinase activity
FY148_11030	COG2198	Histidine kinase
FY148_11030	COG0784	Response regulator, receiver
FY148_11045	COG0726	polysaccharide deacetylase
FY148_11080	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY148_11155	COG0564	pseudouridine synthase activity
FY148_11165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY148_11175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY148_11200	COG0346	lactoylglutathione lyase activity
FY148_11210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY148_11220	COG2832	Protein of unknown function (DUF454)
FY148_11225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY148_11230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_11235	COG4558	Periplasmic binding protein
FY148_11245	COG3721	Heme iron utilization protein
FY148_11260	COG3655	Transcriptional regulator
FY148_11285	COG2205	protein histidine kinase activity
FY148_11330	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_11335	COG4605	iron ion homeostasis
FY148_11340	COG4604	ABC transporter, ATP-binding protein
FY148_11345	COG0783	Belongs to the Dps family
FY148_11360	COG0840	transmembrane signaling receptor activity
FY148_11360	COG2972	Histidine kinase
FY148_11365	COG0656	L-ascorbic acid biosynthetic process
FY148_11370	COG2814	Major facilitator Superfamily
FY148_11380	COG0583	DNA-binding transcription factor activity
FY148_11385	COG0657	acetylesterase activity
FY148_11390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_11410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY148_11415	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY148_11420	COG0288	reversible hydration of carbon dioxide
FY148_11430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY148_11450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY148_11455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY148_11460	COG0778	Nitroreductase
FY148_11465	COG2267	carboxylic ester hydrolase activity
FY148_11470	COG0251	oxidation-reduction process
FY148_11475	COG1335	isochorismatase
FY148_11480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_11490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_11505	COG1175	transmembrane transport
FY148_11510	COG0395	ABC-type sugar transport system, permease component
FY148_11515	COG3842	ATPase activity
FY148_11520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_11530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY148_11545	COG4608	Belongs to the ABC transporter superfamily
FY148_11550	COG0444	Belongs to the ABC transporter superfamily
FY148_11555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_11560	COG0601	transmembrane transport
FY148_11615	COG2159	amidohydrolase
FY148_11620	COG1960	acyl-CoA dehydrogenase activity
FY148_11650	COG0745	RESPONSE REGULATOR receiver
FY148_11660	COG1902	pentaerythritol trinitrate reductase activity
FY148_11660	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY148_11665	COG3842	ATPase activity
FY148_11675	COG1840	ABC-type Fe3 transport system, periplasmic component
FY148_11680	COG1840	ABC-type Fe3 transport system, periplasmic component
FY148_11685	COG0745	RESPONSE REGULATOR receiver
FY148_11695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY148_11700	COG0583	DNA-binding transcription factor activity
FY148_11705	COG1278	Cold shock
FY148_11740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY148_11745	COG1309	transcriptional regulator
FY148_11750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_11755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY148_11765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY148_11770	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY148_11790	COG0583	DNA-binding transcription factor activity
FY148_11795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_11800	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY148_11805	COG4149	molybdate abc transporter
FY148_11810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY148_11825	COG2022	thiamine diphosphate biosynthetic process
FY148_11840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY148_11850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY148_11860	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY148_11880	COG1132	(ABC) transporter
FY148_11885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY148_11930	COG4166	transmembrane transport
FY148_11935	COG0601	transmembrane transport
FY148_11940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_11955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY148_11960	COG3142	Participates in the control of copper homeostasis
FY148_11965	COG2814	Major facilitator Superfamily
FY148_11980	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_11985	COG1737	Transcriptional regulator
FY148_11995	COG3842	ATPase activity
FY148_12005	COG0395	ABC-type sugar transport system, permease component
FY148_12020	COG2188	Transcriptional regulator
FY148_12025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY148_12030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY148_12035	COG1940	carbohydrate kinase activity
FY148_12045	COG0671	phosphoesterase, PA-phosphatase related
FY148_12050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY148_12055	COG0156	8-amino-7-oxononanoate synthase activity
FY148_12065	COG0729	surface antigen
FY148_12075	COG0835	chemotaxis
FY148_12085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY148_12090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY148_12095	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY148_12100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY148_12105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY148_12110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY148_12125	COG4974	Belongs to the 'phage' integrase family
FY148_12150	COG1280	lysine exporter protein (LysE YggA)
FY148_12160	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY148_12165	COG0567	Dehydrogenase, E1 component
FY148_12170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY148_12175	COG0045	succinate-CoA ligase (ADP-forming) activity
FY148_12180	COG0039	L-malate dehydrogenase activity
FY148_12185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY148_12220	COG2264	protein methyltransferase activity
FY148_12235	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY148_12240	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY148_12245	COG0181	hydroxymethylbilane synthase activity
FY148_12285	COG1872	DUF167
FY148_12290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY148_12300	COG1217	gtp-binding protein TYPA
FY148_12305	COG0339	signal peptide processing
FY148_12310	COG1846	Transcriptional regulator
FY148_12320	COG0137	argininosuccinate synthase activity
FY148_12330	COG1280	lysine exporter protein (LysE YggA)
FY148_12335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY148_12340	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY148_12350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY148_12365	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY148_12370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY148_12375	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY148_12385	COG4181	ATPase activity
FY148_12395	COG0670	Belongs to the BI1 family
FY148_12410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY148_12415	COG4133	protoheme IX ABC transporter activity
FY148_12420	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY148_12425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY148_12450	COG2917	probably involved in intracellular septation
FY148_12455	COG0552	protein localization to endoplasmic reticulum
FY148_12460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY148_12465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY148_12475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY148_12480	COG1605	Chorismate mutase
FY148_12480	COG0287	Prephenate dehydrogenase
FY148_12485	COG0228	four-way junction DNA binding
FY148_12490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY148_12495	COG0336	Belongs to the RNA methyltransferase TrmD family
FY148_12505	COG0335	large ribosomal subunit rRNA binding
FY148_12510	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY148_12515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_12530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY148_12550	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY148_12570	COG0488	(ABC) transporter
FY148_12580	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY148_12590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY148_12595	COG0142	geranyltranstransferase activity
FY148_12600	COG2885	chlorophyll binding
FY148_12605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY148_12610	COG2223	nitrite transmembrane transporter activity
FY148_12615	COG1349	DNA-binding transcription factor activity
FY148_12620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY148_12625	COG2197	response regulator
FY148_12630	COG1132	(ABC) transporter
FY148_12640	COG3459	Glycosyltransferase 36 associated
FY148_12645	COG1473	amidohydrolase
FY148_12650	COG0579	oxidoreductase
FY148_12660	COG0129	dihydroxy-acid dehydratase activity
FY148_12665	COG2084	Dehydrogenase
FY148_12670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY148_12675	COG0277	FAD linked oxidase domain protein
FY148_12680	COG2186	Transcriptional regulator
FY148_12690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY148_12695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY148_12700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY148_12705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY148_12715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY148_12720	COG0495	leucyl-tRNA aminoacylation
FY148_12735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY148_12740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY148_12755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY148_12760	COG1946	Acyl-CoA thioesterase
FY148_12765	COG0347	Belongs to the P(II) protein family
FY148_12770	COG0004	ammonium transporteR
FY148_12775	COG1674	ftsk spoiiie
FY148_12780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY148_12795	COG0745	RESPONSE REGULATOR receiver
FY148_12805	COG1329	Transcriptional regulator
FY148_12815	COG2270	Major facilitator Superfamily
FY148_12830	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_12845	COG0494	nUDIX hydrolase
FY148_12850	COG2861	carbohydrate metabolic process
FY148_12855	COG0793	Belongs to the peptidase S41A family
FY148_12865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY148_12870	COG0799	negative regulation of ribosome biogenesis
FY148_12875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY148_12880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY148_12885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY148_12890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY148_12905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY148_12910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY148_12935	COG0066	3-isopropylmalate dehydratase activity
FY148_12940	COG0473	3-isopropylmalate dehydrogenase activity
FY148_12945	COG1858	cytochrome C peroxidase
FY148_12950	COG1797	cobyrinic acid a,c-diamide synthase activity
FY148_12960	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY148_13025	COG1492	cobalamin metabolic process
FY148_13040	COG4948	Mandelate Racemase Muconate Lactonizing
FY148_13045	COG3254	rhamnose metabolic process
FY148_13055	COG1063	alcohol dehydrogenase
FY148_13080	COG1129	ABC transporter
FY148_13085	COG2186	Transcriptional regulator
FY148_13090	COG2721	sulfolactate sulfo-lyase activity
FY148_13095	COG0138	bifunctional purine biosynthesis protein purh
FY148_13105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY148_13105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY148_13110	COG0501	Belongs to the peptidase M48B family
FY148_13130	COG0357	Ribosomal RNA small subunit methyltransferase G
FY148_13135	COG0445	tRNA wobble uridine modification
FY148_13140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY148_13145	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY148_13150	COG1981	membrane
FY148_13155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY148_13160	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY148_13165	COG0424	maF-like protein
FY148_13170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY148_13175	COG0237	dephospho-CoA kinase activity
FY148_13185	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY148_13190	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY148_13200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY148_13225	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY148_13240	COG0135	phosphoribosylanthranilate isomerase activity
FY148_13245	COG0133	tryptophan synthase activity
FY148_13250	COG0159	tryptophan synthase activity
FY148_13255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY148_13270	COG1074	ATP-dependent DNA helicase activity
FY148_13280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY148_13285	COG0802	atpase or kinase
FY148_13290	COG2205	protein histidine kinase activity
FY148_13295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY148_13300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY148_13305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY148_13305	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY148_13310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY148_13315	COG0642	Histidine kinase
FY148_13320	COG0745	RESPONSE REGULATOR receiver
FY148_13325	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY148_13335	COG1652	LysM domain
FY148_13340	COG1072	(Pantothenic acid kinase))
FY148_13345	COG0140	phosphoribosyl-ATP diphosphatase activity
FY148_13350	COG0107	imidazoleglycerol-phosphate synthase activity
FY148_13355	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY148_13360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY148_13370	COG0131	Imidazoleglycerol-phosphate dehydratase
FY148_13375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY148_13380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY148_13390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY148_13405	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY148_13415	COG1643	Atp-dependent helicase
FY148_13460	COG1940	carbohydrate kinase activity
FY148_13480	COG1072	(Pantothenic acid kinase))
FY148_13490	COG1780	Probably involved in ribonucleotide reductase function
FY148_13510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY148_13540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_13550	COG2813	Specifically methylates the guanine in position
FY148_13555	COG1185	polyribonucleotide nucleotidyltransferase activity
FY148_13560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY148_13565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY148_13570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY148_13575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY148_13575	COG3064	Membrane
FY148_13590	COG0779	Required for maturation of 30S ribosomal subunits
FY148_13595	COG2814	Major facilitator Superfamily
FY148_13605	COG2951	lytic endotransglycosylase activity
FY148_13610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY148_13620	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY148_13625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY148_13640	COG2816	NAD+ diphosphatase activity
FY148_13645	COG1605	Chorismate mutase
FY148_13645	COG0077	Prephenate dehydratase
FY148_13650	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY148_13655	COG3474	cytochrome
FY148_13665	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY148_13670	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY148_13675	COG1278	Cold shock
FY148_13680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY148_13690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY148_13690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY148_13695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY148_13725	COG2900	Belongs to the SlyX family
FY148_13735	COG0484	heat shock protein binding
FY148_13740	COG0443	Heat shock 70 kDa protein
FY148_13755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY148_13760	COG1744	ABC transporter substrate-binding protein PnrA-like
FY148_13765	COG3845	ABC transporter
FY148_13770	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY148_13775	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY148_13780	COG0295	cytidine deaminase activity
FY148_13790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY148_13795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY148_13805	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY148_13810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY148_13815	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY148_13825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY148_13830	COG1845	cytochrome c oxidase, subunit III
FY148_13835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY148_13840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY148_13845	COG0477	Major facilitator Superfamily
FY148_13850	COG0069	glutamate synthase activity
FY148_13850	COG0070	glutamate synthase
FY148_13850	COG0067	glutamate synthase
FY148_13855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY148_13870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY148_13880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY148_13910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_13930	COG0848	biopolymer transport protein
FY148_13940	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY148_13955	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY148_13960	COG3454	Phosphonate metabolism
FY148_13965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY148_13970	COG3639	organic phosphonate transmembrane transporter activity
FY148_13975	COG3639	organic phosphonate transmembrane transporter activity
FY148_13985	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY148_13995	COG4778	phosphonate C-P lyase system protein PhnL
FY148_14000	COG4107	phosphonate C-P lyase system protein PhnK
FY148_14005	COG3627	carbon phosphorus lyase activity
FY148_14010	COG3626	phosphonate metabolism
FY148_14015	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY148_14020	COG3624	Phosphonate C-P lyase system protein PhnG
FY148_14025	COG2188	Transcriptional regulator
FY148_14030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY148_14035	COG0837	glucose binding
FY148_14040	COG1803	Methylglyoxal synthase
FY148_14045	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY148_14050	COG4166	transmembrane transport
FY148_14055	COG4174	ABC transporter (Permease)
FY148_14060	COG4239	(ABC) transporter, permease
FY148_14065	COG4172	Belongs to the ABC transporter superfamily
FY148_14070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_14075	COG0174	glutamine synthetase
FY148_14080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_14085	COG3265	gluconokinase activity
FY148_14090	COG1174	glycine betaine transport
FY148_14095	COG1125	glycine betaine transport
FY148_14100	COG1174	glycine betaine transport
FY148_14105	COG1732	Glycine betaine
FY148_14115	COG1959	2 iron, 2 sulfur cluster binding
FY148_14120	COG1840	ABC-type Fe3 transport system, periplasmic component
FY148_14130	COG4269	membrane
FY148_14145	COG0697	spore germination
FY148_14160	COG0791	NLP P60 protein
FY148_14170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY148_14175	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY148_14210	COG4964	Belongs to the GSP D family
FY148_14255	COG3422	double-strand break repair
FY148_14260	COG3757	hydrolase, family 25
FY148_14265	COG0697	spore germination
FY148_14270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY148_14285	COG0492	ferredoxin-NADP+ reductase activity
FY148_14300	COG0481	GTPase activity
FY148_14305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY148_14320	COG1396	sequence-specific DNA binding
FY148_14335	COG1917	Cupin 2, conserved barrel domain protein
FY148_14335	COG2169	Transcriptional regulator
FY148_14340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY148_14365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY148_14370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY148_14375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY148_14385	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY148_14390	COG0072	phenylalanine-tRNA ligase activity
FY148_14390	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY148_14395	COG0667	Aldo Keto reductase
FY148_14415	COG4977	sequence-specific DNA binding
FY148_14440	COG1570	exodeoxyribonuclease VII activity
FY148_14445	COG4948	Mandelate Racemase Muconate Lactonizing
FY148_14455	COG1846	Transcriptional regulator
FY148_14460	COG0697	spore germination
FY148_14465	COG2309	aminopeptidase activity
FY148_14475	COG1393	Belongs to the ArsC family
FY148_14490	COG1309	transcriptional regulator
FY148_14500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY148_14500	COG0519	Catalyzes the synthesis of GMP from XMP
FY148_14515	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY148_14545	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY148_14555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY148_14565	COG1968	undecaprenyl-diphosphatase activity
FY148_14580	COG0284	orotidine-5'-phosphate decarboxylase activity
FY148_14590	COG3963	phosphatidate phosphatase activity
FY148_14600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY148_14605	COG0792	nuclease activity
FY148_14620	COG1175	transmembrane transport
FY148_14625	COG0395	ABC-type sugar transport system, permease component
FY148_14630	COG3842	ATPase activity
FY148_14640	COG0189	ligase activity
FY148_14645	COG0606	chelatase, subunit chli
FY148_14650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY148_14655	COG1280	lysine exporter protein (LysE YggA)
FY148_14660	COG0756	dUTP diphosphatase activity
FY148_14665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY148_14670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY148_14685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY148_14690	COG2226	methyltransferase
FY148_14695	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY148_14700	COG1024	Enoyl-CoA hydratase
FY148_14705	COG0268	Binds directly to 16S ribosomal RNA
FY148_14720	COG2274	protein secretion by the type I secretion system
FY148_14735	COG0640	Transcriptional regulator
FY148_14770	COG4178	(ABC) transporter
FY148_14795	COG1082	Xylose isomerase domain protein TIM barrel
FY148_14800	COG0572	uridine kinase
FY148_14810	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_14815	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_14820	COG1129	ABC transporter
FY148_14840	COG3284	Transcriptional regulator
FY148_14845	COG1063	alcohol dehydrogenase
FY148_14855	COG0110	maltose O-acetyltransferase activity
FY148_14860	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY148_14885	COG0488	(ABC) transporter
FY148_14890	COG5265	(ABC) transporter
FY148_14895	COG3181	Tripartite tricarboxylate transporter family receptor
FY148_14900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY148_14910	COG3237	CsbD-like
FY148_14930	COG0395	ABC-type sugar transport system, permease component
FY148_14935	COG3842	ATPase activity
FY148_14945	COG0483	inositol monophosphate 1-phosphatase activity
FY148_14955	COG0405	Gamma-glutamyltransferase
FY148_14960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_14965	COG0601	transmembrane transport
FY148_14970	COG0747	negative chemotaxis
FY148_14975	COG2186	Transcriptional regulator
FY148_14985	COG4948	Mandelate Racemase Muconate Lactonizing
FY148_14990	COG4172	Belongs to the ABC transporter superfamily
FY148_14995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_15000	COG0601	transmembrane transport
FY148_15005	COG0747	negative chemotaxis
FY148_15010	COG2186	Transcriptional regulator
FY148_15020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_15025	COG2223	nitrite transmembrane transporter activity
FY148_15035	COG3383	formate dehydrogenase (NAD+) activity
FY148_15055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY148_15070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY148_15080	COG0765	amino acid transport
FY148_15085	COG0765	amino acid transport
FY148_15090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_15105	COG3938	Belongs to the proline racemase family
FY148_15115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_15125	COG0765	amino acid transport
FY148_15140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY148_15145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_15155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY148_15160	COG0784	Response regulator, receiver
FY148_15180	COG0842	Transport permease protein
FY148_15185	COG0842	Transport permease protein
FY148_15185	COG1129	ABC transporter
FY148_15190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_15195	COG1486	melibiose metabolic process
FY148_15200	COG4172	Belongs to the ABC transporter superfamily
FY148_15205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_15210	COG0601	transmembrane transport
FY148_15215	COG0747	negative chemotaxis
FY148_15220	COG1486	melibiose metabolic process
FY148_15245	COG1940	carbohydrate kinase activity
FY148_15250	COG2182	Extracellular solute-binding protein
FY148_15255	COG1175	transmembrane transport
FY148_15260	COG0395	ABC-type sugar transport system, permease component
FY148_15265	COG0165	Argininosuccinate lyase
FY148_15270	COG3842	ATPase activity
FY148_15275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_15280	COG3119	arylsulfatase activity
FY148_15290	COG0583	DNA-binding transcription factor activity
FY148_15295	COG1120	ATPase activity
FY148_15300	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_15305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_15315	COG4774	siderophore transport
FY148_15325	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY148_15340	COG2205	protein histidine kinase activity
FY148_15345	COG0745	RESPONSE REGULATOR receiver
FY148_15350	COG1566	PFAM secretion protein HlyD family protein
FY148_15365	COG1392	Phosphate transport regulator
FY148_15370	COG0306	phosphate transporter
FY148_15375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY148_15385	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY148_15395	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_15400	COG5001	Diguanylate cyclase
FY148_15400	COG3300	MHYT domain
FY148_15425	COG0601	transmembrane transport
FY148_15430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_15435	COG0444	Belongs to the ABC transporter superfamily
FY148_15445	COG3842	ATPase activity
FY148_15450	COG0395	ABC-type sugar transport system, permease component
FY148_15465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY148_15465	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY148_15470	COG1609	Transcriptional regulator
FY148_15480	COG0210	DNA helicase
FY148_15485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY148_15490	COG1088	dTDP-glucose 4,6-dehydratase activity
FY148_15495	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY148_15500	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY148_15515	COG3754	Rhamnan synthesis protein F
FY148_15520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY148_15540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY148_15550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY148_15555	COG1216	Glycosyl transferase, family 2
FY148_15555	COG1442	glycosyl transferase family 8
FY148_15570	COG1132	(ABC) transporter
FY148_15580	COG0583	DNA-binding transcription factor activity
FY148_15585	COG0667	Aldo Keto reductase
FY148_15605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY148_15620	COG0300	oxidoreductase activity
FY148_15625	COG0584	glycerophosphoryl diester phosphodiesterase
FY148_15630	COG1940	carbohydrate kinase activity
FY148_15640	COG3712	iron ion homeostasis
FY148_15645	COG4774	siderophore transport
FY148_15650	COG2814	Major facilitator Superfamily
FY148_15670	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY148_15680	COG3842	ATPase activity
FY148_15685	COG1175	transmembrane transport
FY148_15690	COG0395	ABC-type sugar transport system, permease component
FY148_15695	COG1609	Transcriptional regulator
FY148_15705	COG0673	inositol 2-dehydrogenase activity
FY148_15710	COG1082	Xylose isomerase domain protein TIM barrel
FY148_15725	COG1609	Transcriptional regulator
FY148_15730	COG0183	Belongs to the thiolase family
FY148_15735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY148_15745	COG1414	Transcriptional regulator
FY148_15760	COG0583	DNA-binding transcription factor activity
FY148_15770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY148_15775	COG3485	protocatechuate 3,4-dioxygenase
FY148_15780	COG3485	protocatechuate 3,4-dioxygenase
FY148_15785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY148_15790	COG0765	amino acid transport
FY148_15795	COG0765	amino acid transport
FY148_15800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_15805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_15810	COG1126	abc transporter atp-binding protein
FY148_15815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY148_15820	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY148_15845	COG4172	Belongs to the ABC transporter superfamily
FY148_15850	COG0747	negative chemotaxis
FY148_15860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_15875	COG0683	leucine binding
FY148_15890	COG0411	ABC transporter
FY148_15905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_15910	COG3962	Belongs to the TPP enzyme family
FY148_15920	COG3718	enzyme involved in inositol metabolism
FY148_15930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY148_15935	COG1609	Transcriptional regulator
FY148_15940	COG1846	Transcriptional regulator
FY148_15950	COG0523	cobalamin synthesis protein
FY148_15985	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY148_16005	COG0800	Aldolase
FY148_16010	COG2954	triphosphatase activity
FY148_16020	COG1054	Belongs to the UPF0176 family
FY148_16025	COG3300	MHYT domain
FY148_16025	COG5001	Diguanylate cyclase
FY148_16035	COG2011	ABC-type metal ion transport system permease component
FY148_16040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY148_16045	COG0778	Nitroreductase
FY148_16055	COG2115	Belongs to the xylose isomerase family
FY148_16060	COG1070	Carbohydrate kinase
FY148_16065	COG1609	Transcriptional regulator
FY148_16085	COG1309	transcriptional regulator
FY148_16090	COG1253	flavin adenine dinucleotide binding
FY148_16095	COG0471	metal ion transport
FY148_16095	COG3273	potassium ion transport
FY148_16100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY148_16105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY148_16110	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY148_16120	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY148_16125	COG1121	(ABC) transporter
FY148_16130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY148_16135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY148_16145	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_16150	COG1414	Transcriptional regulator
FY148_16155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY148_16175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY148_16200	COG1069	ribulokinase activity
FY148_16225	COG0395	ABC-type sugar transport system, permease component
FY148_16230	COG1175	transmembrane transport
FY148_16240	COG2390	Transcriptional regulator
FY148_16245	COG4172	Belongs to the ABC transporter superfamily
FY148_16250	COG1473	amidohydrolase
FY148_16260	COG0601	transmembrane transport
FY148_16265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_16275	COG0693	protein deglycase activity
FY148_16280	COG0154	amidase activity
FY148_16285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_16295	COG0747	negative chemotaxis
FY148_16300	COG0583	DNA-binding transcription factor activity
FY148_16305	COG4608	Belongs to the ABC transporter superfamily
FY148_16310	COG0444	Belongs to the ABC transporter superfamily
FY148_16315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_16320	COG0601	transmembrane transport
FY148_16325	COG0747	negative chemotaxis
FY148_16335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY148_16340	COG1473	amidohydrolase
FY148_16345	COG2814	Major facilitator Superfamily
FY148_16350	COG0583	DNA-binding transcription factor activity
FY148_16355	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY148_16375	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_16385	COG1609	Transcriptional regulator
FY148_16390	COG0583	DNA-binding transcription factor activity
FY148_16395	COG1960	acyl-CoA dehydrogenase activity
FY148_16400	COG1629	transport
FY148_16400	COG4774	siderophore transport
FY148_16410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_16420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_16425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_16435	COG2375	cellular response to nickel ion
FY148_16445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY148_16450	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY148_16450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY148_16460	COG1169	isochorismate synthase
FY148_16465	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY148_16470	COG3433	isochorismatase activity
FY148_16470	COG1535	isochorismatase
FY148_16475	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_16490	COG3005	denitrification pathway
FY148_16500	COG0243	molybdopterin cofactor binding
FY148_16515	COG4459	periplasmic nitrate reductase
FY148_16525	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY148_16550	COG0826	peptidase U32
FY148_16560	COG3189	MarR family transcriptional regulator
FY148_16565	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY148_16595	COG3256	nitric oxide reductase
FY148_16600	COG0714	Associated with various cellular activities
FY148_16660	COG0673	inositol 2-dehydrogenase activity
FY148_16670	COG1609	Transcriptional regulator
FY148_16675	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_16680	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_16685	COG1129	ABC transporter
FY148_16690	COG1879	ABC-type sugar transport system periplasmic component
FY148_16700	COG0583	DNA-binding transcription factor activity
FY148_16715	COG1609	Transcriptional regulator
FY148_16720	COG0673	inositol 2-dehydrogenase activity
FY148_16730	COG1653	transport
FY148_16735	COG1175	transmembrane transport
FY148_16740	COG0395	ABC-type sugar transport system, permease component
FY148_16745	COG3842	ATPase activity
FY148_16760	COG1253	flavin adenine dinucleotide binding
FY148_16785	COG3300	MHYT domain
FY148_16785	COG5001	Diguanylate cyclase
FY148_16915	COG0477	Major facilitator Superfamily
FY148_16935	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_16945	COG1879	ABC-type sugar transport system periplasmic component
FY148_16955	COG1063	alcohol dehydrogenase
FY148_16970	COG1136	(ABC) transporter
FY148_16985	COG1309	transcriptional regulator
FY148_17000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY148_17010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY148_17010	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY148_17020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_17025	COG0047	phosphoribosylformylglycinamidine synthase activity
FY148_17035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_17040	COG1012	belongs to the aldehyde dehydrogenase family
FY148_17045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_17055	COG4175	Glycine betaine
FY148_17055	COG3448	diguanylate cyclase activity
FY148_17065	COG4176	ABC-type proline glycine betaine transport system permease component
FY148_17070	COG3938	Belongs to the proline racemase family
FY148_17075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY148_17110	COG1733	regulation of RNA biosynthetic process
FY148_17120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FY148_17160	COG0477	Major facilitator Superfamily
FY148_17170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY148_17175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY148_17190	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_17200	COG0395	ABC-type sugar transport system, permease component
FY148_17225	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_17230	COG1349	DNA-binding transcription factor activity
FY148_17235	COG1069	ribulokinase activity
FY148_17255	COG1940	carbohydrate kinase activity
FY148_17270	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_17275	COG1177	transmembrane transport
FY148_17285	COG3842	ATPase activity
FY148_17340	COG0577	efflux transmembrane transporter activity
FY148_17340	COG1136	(ABC) transporter
FY148_17365	COG1845	cytochrome c oxidase, subunit III
FY148_17370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY148_17375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY148_17380	COG3474	cytochrome
FY148_17405	COG3842	ATPase activity
FY148_17410	COG0395	ABC-type sugar transport system, permease component
FY148_17415	COG1175	transmembrane transport
FY148_17420	COG1653	transport
FY148_17425	COG1012	belongs to the aldehyde dehydrogenase family
FY148_17430	COG1024	Enoyl-CoA hydratase
FY148_17450	COG4702	Belongs to the UPF0303 family
FY148_17455	COG1629	transport
FY148_17455	COG4774	siderophore transport
FY148_17460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY148_17465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_17470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_17475	COG1120	ATPase activity
FY148_17490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY148_17500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY148_17505	COG1177	transmembrane transport
FY148_17510	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_17515	COG3842	ATPase activity
FY148_17540	COG1335	isochorismatase
FY148_17555	COG0583	DNA-binding transcription factor activity
FY148_17560	COG2318	DinB family
FY148_17585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY148_17615	COG0778	Nitroreductase
FY148_17635	COG0277	FAD linked oxidase domain protein
FY148_17655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_17660	COG4172	Belongs to the ABC transporter superfamily
FY148_17670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_17680	COG0431	NADPH-dependent FMN reductase
FY148_17700	COG1522	sequence-specific DNA binding
FY148_17705	COG2376	Dihydroxyacetone kinase
FY148_17810	COG3609	addiction module antidote protein, CC2985 family
FY148_17850	COG0739	heme binding
FY148_17850	COG0741	lytic transglycosylase activity
FY148_17850	COG1196	nuclear chromosome segregation
FY148_17855	COG0542	response to heat
FY148_17865	COG2890	protein-(glutamine-N5) methyltransferase activity
FY148_17870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY148_17880	COG0527	aspartate kinase activity
FY148_17895	COG0019	diaminopimelate decarboxylase activity
FY148_17910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY148_17920	COG3920	Histidine kinase
FY148_17930	COG0784	Response regulator, receiver
FY148_17945	COG1522	sequence-specific DNA binding
FY148_17955	COG1116	anion transmembrane transporter activity
FY148_17960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_17965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY148_17970	COG1012	belongs to the aldehyde dehydrogenase family
FY148_17975	COG0583	DNA-binding transcription factor activity
FY148_17980	COG0435	Glutathione S-transferase
FY148_17995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY148_18000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY148_18005	COG0189	ligase activity
FY148_18025	COG0693	protein deglycase activity
FY148_18055	COG3685	Protein conserved in bacteria
FY148_18060	COG4993	Dehydrogenase
FY148_18075	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_18080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY148_18125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_18140	COG0246	Mannitol dehydrogenase
FY148_18145	COG4608	Belongs to the ABC transporter superfamily
FY148_18150	COG0444	Belongs to the ABC transporter superfamily
FY148_18155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_18160	COG0601	transmembrane transport
FY148_18165	COG0747	negative chemotaxis
FY148_18175	COG4221	oxidoreductase activity
FY148_18205	COG0539	negative regulation of cytoplasmic translation
FY148_18210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY148_18240	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY148_18245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY148_18275	COG1294	oxidase, subunit
FY148_18285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY148_18290	COG4988	ABC transporter
FY148_18300	COG1063	alcohol dehydrogenase
FY148_18305	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_18310	COG2084	Dehydrogenase
FY148_18320	COG1522	sequence-specific DNA binding
FY148_18325	COG1794	racemase activity, acting on amino acids and derivatives
FY148_18340	COG0058	SHG alpha-glucan phosphorylase activity
FY148_18345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY148_18350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY148_18355	COG0297	glycogen (starch) synthase activity
FY148_18360	COG0033	Phosphoglucomutase
FY148_18365	COG1523	belongs to the glycosyl hydrolase 13 family
FY148_18395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY148_18395	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY148_18410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_18415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY148_18435	COG1215	transferase activity, transferring glycosyl groups
FY148_18440	COG2327	Polysaccharide pyruvyl transferase
FY148_18445	COG0463	Glycosyl transferase, family 2
FY148_18450	COG2244	polysaccharide biosynthetic process
FY148_18455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY148_18460	COG2273	Hydrolase Family 16
FY148_18465	COG0438	transferase activity, transferring glycosyl groups
FY148_18470	COG1215	transferase activity, transferring glycosyl groups
FY148_18475	COG1215	transferase activity, transferring glycosyl groups
FY148_18480	COG1215	transferase activity, transferring glycosyl groups
FY148_18485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY148_18490	COG0489	protein tyrosine kinase activity
FY148_18490	COG3206	protein involved in exopolysaccharide biosynthesis
FY148_18495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY148_18500	COG0784	Response regulator, receiver
FY148_18500	COG4191	Histidine kinase
FY148_18515	COG4176	ABC-type proline glycine betaine transport system permease component
FY148_18520	COG3448	diguanylate cyclase activity
FY148_18520	COG4175	Glycine betaine
FY148_18535	COG0564	pseudouridine synthase activity
FY148_18540	COG0500	methyltransferase
FY148_18550	COG2133	pyrroloquinoline quinone binding
FY148_18560	COG2197	response regulator
FY148_18565	COG4585	Histidine kinase
FY148_18570	COG1879	ABC-type sugar transport system periplasmic component
FY148_18575	COG1129	ABC transporter
FY148_18580	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_18590	COG3386	PFAM SMP-30 Gluconolaconase
FY148_18595	COG2137	regulation of response to DNA damage stimulus
FY148_18600	COG3474	cytochrome
FY148_18610	COG1120	ATPase activity
FY148_18625	COG4774	siderophore transport
FY148_18630	COG0583	DNA-binding transcription factor activity
FY148_18640	COG2194	sulfuric ester hydrolase activity
FY148_18655	COG0477	Major facilitator Superfamily
FY148_18680	COG0673	inositol 2-dehydrogenase activity
FY148_18685	COG0697	spore germination
FY148_18695	COG0010	Belongs to the arginase family
FY148_18710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY148_18715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY148_18720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY148_18725	COG0156	8-amino-7-oxononanoate synthase activity
FY148_18730	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY148_18780	COG0671	phosphoesterase, PA-phosphatase related
FY148_18785	COG0745	RESPONSE REGULATOR receiver
FY148_18790	COG2205	protein histidine kinase activity
FY148_18800	COG0477	Major facilitator Superfamily
FY148_18805	COG0583	DNA-binding transcription factor activity
FY148_18825	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY148_18840	COG0346	lactoylglutathione lyase activity
FY148_18845	COG0583	DNA-binding transcription factor activity
FY148_18875	COG1215	transferase activity, transferring glycosyl groups
FY148_18895	COG0840	transmembrane signaling receptor activity
FY148_18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_18925	COG2828	Protein conserved in bacteria
FY148_18930	COG0583	DNA-binding transcription factor activity
FY148_18935	COG1846	Transcriptional regulator
FY148_18960	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_18965	COG1309	transcriptional regulator
FY148_18970	COG2207	Transcriptional regulator
FY148_18985	COG1566	PFAM secretion protein HlyD family protein
FY148_19000	COG0395	ABC-type sugar transport system, permease component
FY148_19005	COG4166	transmembrane transport
FY148_19010	COG0601	transmembrane transport
FY148_19015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_19020	COG4172	Belongs to the ABC transporter superfamily
FY148_19025	COG4221	oxidoreductase activity
FY148_19030	COG0625	glutathione transferase activity
FY148_19040	COG1566	PFAM secretion protein HlyD family protein
FY148_19050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY148_19055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY148_19070	COG0534	Mate efflux family protein
FY148_19105	COG1733	regulation of RNA biosynthetic process
FY148_19115	COG0577	efflux transmembrane transporter activity
FY148_19115	COG1136	(ABC) transporter
FY148_19120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_19130	COG0745	RESPONSE REGULATOR receiver
FY148_19150	COG3209	COG3209 Rhs family protein
FY148_19180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_19205	COG3177	Filamentation induced by cAMP protein fic
FY148_19220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_19225	COG4597	amino acid ABC transporter
FY148_19230	COG0765	amino acid transport
FY148_19255	COG0747	negative chemotaxis
FY148_19260	COG0601	transmembrane transport
FY148_19265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_19270	COG0444	Belongs to the ABC transporter superfamily
FY148_19275	COG4608	Belongs to the ABC transporter superfamily
FY148_19295	COG4213	ABC transporter substrate-binding protein
FY148_19300	COG1129	ABC transporter
FY148_19305	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_19320	COG0667	Aldo Keto reductase
FY148_19345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_19350	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_19355	COG1129	ABC transporter
FY148_19365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_19375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_19385	COG0747	negative chemotaxis
FY148_19390	COG0747	negative chemotaxis
FY148_19395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_19405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_19410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_19415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY148_19445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_19450	COG0436	Aminotransferase
FY148_19465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_19470	COG0765	amino acid transport
FY148_19480	COG1126	abc transporter atp-binding protein
FY148_19490	COG2186	Transcriptional regulator
FY148_19510	COG1846	Transcriptional regulator
FY148_19515	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_19525	COG0583	DNA-binding transcription factor activity
FY148_19560	COG0583	DNA-binding transcription factor activity
FY148_19580	COG1280	lysine exporter protein (LysE YggA)
FY148_19585	COG3920	Histidine kinase
FY148_19610	COG0753	catalase activity
FY148_19630	COG1278	Cold shock
FY148_19660	COG2267	carboxylic ester hydrolase activity
FY148_19665	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_19670	COG1902	pentaerythritol trinitrate reductase activity
FY148_19675	COG4221	oxidoreductase activity
FY148_19680	COG1309	transcriptional regulator
FY148_19695	COG1280	lysine exporter protein (LysE YggA)
FY148_19705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY148_19755	COG0402	S-adenosylhomocysteine deaminase activity
FY148_19760	COG1228	amidohydrolase
FY148_19765	COG2986	histidine ammonia-lyase
FY148_19775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY148_19805	COG1192	Involved in chromosome partitioning
FY148_19810	COG1475	DNA binding
FY148_19815	COG1414	Transcriptional regulator
FY148_19835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY148_19840	COG4771	TonB-dependent receptor
FY148_19850	COG0366	Alpha amylase catalytic
FY148_19855	COG4770	biotin carboxylase activity
FY148_19860	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY148_19865	COG4336	lyase activity
FY148_19870	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY148_19875	COG1914	H( )-stimulated, divalent metal cation uptake system
FY148_19880	COG1802	Transcriptional regulator
FY148_19885	COG3707	response regulator
FY148_19895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY148_19900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_19905	COG1116	anion transmembrane transporter activity
FY148_19910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY148_19920	COG0243	molybdopterin cofactor binding
FY148_19925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY148_19925	COG1648	precorrin-2 dehydrogenase activity
FY148_19940	COG3842	ATPase activity
FY148_19955	COG0395	ABC-type sugar transport system, permease component
FY148_19970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY148_19985	COG0071	Belongs to the small heat shock protein (HSP20) family
FY148_20030	COG1879	ABC-type sugar transport system periplasmic component
FY148_20035	COG1129	ABC transporter
FY148_20040	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_20050	COG0667	Aldo Keto reductase
FY148_20055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY148_20060	COG1830	Aldolase
FY148_20065	COG1070	Carbohydrate kinase
FY148_20070	COG2972	Histidine kinase
FY148_20070	COG0840	transmembrane signaling receptor activity
FY148_20085	COG0436	Aminotransferase
FY148_20095	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY148_20105	COG3842	ATPase activity
FY148_20110	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY148_20115	COG1984	allophanate hydrolase subunit 2
FY148_20120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY148_20130	COG0439	Biotin carboxylase
FY148_20135	COG0511	ligase activity, forming carbon-carbon bonds
FY148_20140	COG0697	spore germination
FY148_20145	COG0697	spore germination
FY148_20160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY148_20175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY148_20180	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_20185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY148_20190	COG4221	oxidoreductase activity
FY148_20195	COG0765	amino acid transport
FY148_20200	COG0765	amino acid transport
FY148_20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_20215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY148_20220	COG1063	alcohol dehydrogenase
FY148_20235	COG1304	FMN binding
FY148_20260	COG3842	ATPase activity
FY148_20270	COG0395	ABC-type sugar transport system, permease component
FY148_20275	COG1175	transmembrane transport
FY148_20290	COG2186	Transcriptional regulator
FY148_20295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY148_20300	COG0488	(ABC) transporter
FY148_20315	COG2307	Protein conserved in bacteria
FY148_20315	COG2308	Evidence 4 Homologs of previously reported genes of
FY148_20355	COG1454	alcohol dehydrogenase
FY148_20360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY148_20370	COG0747	negative chemotaxis
FY148_20375	COG0601	transmembrane transport
FY148_20380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_20390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_20400	COG1078	dGTPase activity
FY148_20425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY148_20445	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FY148_20450	COG0732	type I restriction modification DNA specificity domain
FY148_20475	COG1082	Xylose isomerase domain protein TIM barrel
FY148_20480	COG1082	Xylose isomerase domain protein TIM barrel
FY148_20485	COG0673	inositol 2-dehydrogenase activity
FY148_20490	COG1082	Xylose isomerase domain protein TIM barrel
FY148_20510	COG1609	Transcriptional regulator
FY148_20515	COG2986	histidine ammonia-lyase
FY148_20520	COG3448	diguanylate cyclase activity
FY148_20520	COG4175	Glycine betaine
FY148_20525	COG4176	ABC-type proline glycine betaine transport system permease component
FY148_20545	COG1309	transcriptional regulator
FY148_20565	COG2186	Transcriptional regulator
FY148_20570	COG1027	Aspartate ammonia-lyase
FY148_20580	COG0252	asparaginase activity
FY148_20590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY148_20595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY148_20600	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY148_20605	COG2205	protein histidine kinase activity
FY148_20620	COG0067	glutamate synthase
FY148_20620	COG0069	glutamate synthase activity
FY148_20620	COG0070	glutamate synthase
FY148_20635	COG2205	protein histidine kinase activity
FY148_20640	COG0745	RESPONSE REGULATOR receiver
FY148_20650	COG2951	lytic endotransglycosylase activity
FY148_20655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY148_20685	COG0330	HflC and HflK could
FY148_20690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY148_20695	COG0737	Belongs to the 5'-nucleotidase family
FY148_20705	COG5310	Homospermidine synthase
FY148_20715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY148_20720	COG1164	Oligoendopeptidase f
FY148_20730	COG3108	Peptidase M15
FY148_20735	COG0469	pyruvate kinase activity
FY148_20755	COG3750	Belongs to the UPF0335 family
FY148_20760	COG0457	Tetratricopeptide repeat
FY148_20765	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY148_20770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY148_20775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY148_20805	COG0483	inositol monophosphate 1-phosphatase activity
FY148_20825	COG1132	(ABC) transporter
FY148_20830	COG0254	rRNA binding
FY148_20850	COG3588	fructose-bisphosphate aldolase
FY148_20855	COG0126	phosphoglycerate kinase activity
FY148_20895	COG1253	flavin adenine dinucleotide binding
FY148_20905	COG1692	metallophosphoesterase
FY148_20920	COG0217	transcriptional regulatory protein
FY148_20925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_20930	COG0840	transmembrane signaling receptor activity
FY148_20930	COG2972	Histidine kinase
FY148_20935	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY148_20940	COG0632	four-way junction helicase activity
FY148_20945	COG2255	four-way junction helicase activity
FY148_20960	COG0494	nUDIX hydrolase
FY148_20970	COG0824	Thioesterase
FY148_20990	COG0823	Involved in the tonB-independent uptake of proteins
FY148_20995	COG2885	chlorophyll binding
FY148_21005	COG0037	tRNA processing
FY148_21010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY148_21015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY148_21030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY148_21045	COG0482	sulfurtransferase activity
FY148_21080	COG2835	tetraacyldisaccharide 4'-kinase activity
FY148_21085	COG2373	Large extracellular alpha-helical protein
FY148_21090	COG4953	penicillin-binding protein 1C
FY148_21100	COG1473	amidohydrolase
FY148_21105	COG1686	Belongs to the peptidase S11 family
FY148_21110	COG0523	cobalamin synthesis protein
FY148_21115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY148_21115	COG0425	Belongs to the sulfur carrier protein TusA family
FY148_21120	COG3034	peptidoglycan biosynthetic process
FY148_21125	COG0825	malonyl-CoA metabolic process
FY148_21130	COG4974	Belongs to the 'phage' integrase family
FY148_21140	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY148_21145	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY148_21185	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY148_21190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY148_21210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY148_21215	COG2226	methyltransferase
FY148_21220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY148_21225	COG0287	Prephenate dehydrogenase
FY148_21235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY148_21255	COG2884	Cell division ATP-binding protein ftsE
FY148_21290	COG0165	Argininosuccinate lyase
FY148_21295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY148_21305	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY148_21315	COG2086	electron transfer activity
FY148_21325	COG2096	Adenosyltransferase
FY148_21335	COG0300	oxidoreductase activity
FY148_21345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY148_21355	COG3800	Transcriptional regulator
FY148_21355	COG1396	sequence-specific DNA binding
FY148_21360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY148_21365	COG0625	glutathione transferase activity
FY148_21380	COG4770	biotin carboxylase activity
FY148_21385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY148_21385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY148_21390	COG0346	lactoylglutathione lyase activity
FY148_21405	COG4213	ABC transporter substrate-binding protein
FY148_21410	COG4214	carbohydrate transport
FY148_21415	COG1129	ABC transporter
FY148_21420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY148_21430	COG1396	sequence-specific DNA binding
FY148_21485	COG3833	ABC-type maltose transport systems, permease component
FY148_21490	COG3842	ATPase activity
FY148_21505	COG2273	Hydrolase Family 16
FY148_21505	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY148_21510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY148_21525	COG0438	transferase activity, transferring glycosyl groups
FY148_21530	COG0438	transferase activity, transferring glycosyl groups
FY148_21550	COG3206	protein involved in exopolysaccharide biosynthesis
FY148_21550	COG0489	protein tyrosine kinase activity
FY148_21560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY148_21575	COG2244	polysaccharide biosynthetic process
FY148_21640	COG0697	spore germination
FY148_21645	COG0653	protein targeting
FY148_21650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY148_21655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY148_21665	COG0494	nUDIX hydrolase
FY148_21680	COG2226	methyltransferase
FY148_21685	COG1040	competence protein
FY148_21695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY148_21705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY148_21720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY148_21725	COG4150	thiosulfate binding
FY148_21735	COG4208	sulfate ABC transporter
FY148_21740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY148_21745	COG4335	DNA alkylation repair
FY148_21760	COG5001	Diguanylate cyclase
FY148_21765	COG2264	protein methyltransferase activity
FY148_21780	COG3254	rhamnose metabolic process
FY148_21785	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_21790	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_21795	COG1129	ABC transporter
FY148_21805	COG1349	DNA-binding transcription factor activity
FY148_21810	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_21810	COG3347	Dehydrogenase
FY148_21815	COG4952	isomerase
FY148_21820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY148_21825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY148_21845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY148_21850	COG1960	acyl-CoA dehydrogenase activity
FY148_21860	COG0183	Belongs to the thiolase family
FY148_21865	COG1960	acyl-CoA dehydrogenase activity
FY148_21875	COG0022	dehydrogenase e1 component
FY148_21885	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY148_21890	COG2391	methyltransferase activity
FY148_21900	COG0640	Transcriptional regulator
FY148_21905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY148_21905	COG3453	Protein conserved in bacteria
FY148_21915	COG0300	oxidoreductase activity
FY148_21930	COG2186	Transcriptional regulator
FY148_21940	COG0601	transmembrane transport
FY148_21950	COG0444	Belongs to the ABC transporter superfamily
FY148_21955	COG4608	Belongs to the ABC transporter superfamily
FY148_21975	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_21980	COG1733	regulation of RNA biosynthetic process
FY148_21990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_21995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22015	COG1473	amidohydrolase
FY148_22020	COG0747	negative chemotaxis
FY148_22030	COG4166	transmembrane transport
FY148_22035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22040	COG0583	DNA-binding transcription factor activity
FY148_22050	COG0667	Aldo Keto reductase
FY148_22060	COG0444	Belongs to the ABC transporter superfamily
FY148_22075	COG0747	negative chemotaxis
FY148_22085	COG1960	acyl-CoA dehydrogenase activity
FY148_22115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY148_22130	COG1959	2 iron, 2 sulfur cluster binding
FY148_22135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22145	COG1473	amidohydrolase
FY148_22155	COG1126	abc transporter atp-binding protein
FY148_22160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_22170	COG0583	DNA-binding transcription factor activity
FY148_22185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_22195	COG1522	sequence-specific DNA binding
FY148_22200	COG4172	Belongs to the ABC transporter superfamily
FY148_22205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_22240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_22245	COG1012	belongs to the aldehyde dehydrogenase family
FY148_22250	COG0473	3-isopropylmalate dehydrogenase activity
FY148_22255	COG1012	belongs to the aldehyde dehydrogenase family
FY148_22300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_22305	COG1120	ATPase activity
FY148_22315	COG2226	methyltransferase
FY148_22330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_22335	COG1120	ATPase activity
FY148_22340	COG1595	DNA-templated transcription, initiation
FY148_22360	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY148_22365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_22385	COG0673	inositol 2-dehydrogenase activity
FY148_22390	COG0673	inositol 2-dehydrogenase activity
FY148_22400	COG1175	transmembrane transport
FY148_22405	COG0395	ABC-type sugar transport system, permease component
FY148_22420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY148_22425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY148_22430	COG2197	response regulator
FY148_22435	COG0601	transmembrane transport
FY148_22440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_22460	COG0747	negative chemotaxis
FY148_22475	COG1446	asparaginase
FY148_22480	COG0583	DNA-binding transcription factor activity
FY148_22485	COG0601	transmembrane transport
FY148_22490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_22505	COG0747	negative chemotaxis
FY148_22510	COG1473	amidohydrolase
FY148_22525	COG1129	ABC transporter
FY148_22530	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_22535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY148_22540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY148_22550	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY148_22565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_22575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_22580	COG2079	MmgE PrpD family protein
FY148_22585	COG1126	abc transporter atp-binding protein
FY148_22590	COG0765	amino acid transport
FY148_22605	COG0280	phosphate acetyltransferase
FY148_22605	COG0281	malic enzyme
FY148_22610	COG0583	DNA-binding transcription factor activity
FY148_22635	COG1175	transmembrane transport
FY148_22640	COG0395	ABC-type sugar transport system, permease component
FY148_22655	COG0673	inositol 2-dehydrogenase activity
FY148_22660	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY148_22665	COG0720	synthase
FY148_22670	COG0602	queuosine metabolic process
FY148_22675	COG0673	inositol 2-dehydrogenase activity
FY148_22685	COG3842	ATPase activity
FY148_22700	COG1653	transport
FY148_22705	COG1609	Transcriptional regulator
FY148_22720	COG2094	Belongs to the DNA glycosylase MPG family
FY148_22730	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_22740	COG1376	ErfK ybiS ycfS ynhG family protein
FY148_22745	COG0840	transmembrane signaling receptor activity
FY148_22745	COG2972	Histidine kinase
FY148_22750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY148_22760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY148_22765	COG1596	polysaccharide export
FY148_22770	COG3307	-O-antigen
FY148_22800	COG2197	response regulator
FY148_22810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY148_22835	COG2942	2-epimerase
FY148_22845	COG1215	transferase activity, transferring glycosyl groups
FY148_22865	COG1473	amidohydrolase
FY148_22875	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_22880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY148_22885	COG1301	dicarboxylic acid transport
FY148_22890	COG4191	Histidine kinase
FY148_22895	COG2204	response regulator
FY148_22910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_22915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY148_22920	COG1522	sequence-specific DNA binding
FY148_22925	COG0351	phosphomethylpyrimidine kinase
FY148_22930	COG0352	thiamine-phosphate diphosphorylase activity
FY148_22935	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY148_22940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY148_22945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_22955	COG1501	Belongs to the glycosyl hydrolase 31 family
FY148_22960	COG0395	ABC-type sugar transport system, permease component
FY148_22965	COG1175	transmembrane transport
FY148_22970	COG1653	transport
FY148_22975	COG3842	ATPase activity
FY148_22980	COG2188	Transcriptional regulator
FY148_22990	COG4989	oxidoreductase activity
FY148_23025	COG0438	transferase activity, transferring glycosyl groups
FY148_23030	COG0747	negative chemotaxis
FY148_23035	COG0601	transmembrane transport
FY148_23045	COG3964	amidohydrolase
FY148_23060	COG1921	L-seryl-tRNASec selenium transferase activity
FY148_23065	COG4172	Belongs to the ABC transporter superfamily
FY148_23070	COG0625	glutathione transferase activity
FY148_23085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_23090	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY148_23090	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY148_23095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY148_23115	COG1312	Catalyzes the dehydration of D-mannonate
FY148_23120	COG1063	alcohol dehydrogenase
FY148_23125	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY148_23135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY148_23140	COG2186	Transcriptional regulator
FY148_23145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY148_23150	COG0850	regulation of cytokinetic process
FY148_23155	COG2894	cell division
FY148_23160	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY148_23165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_23175	COG5001	Diguanylate cyclase
FY148_23190	COG0673	inositol 2-dehydrogenase activity
FY148_23200	COG1653	transport
FY148_23205	COG1175	transmembrane transport
FY148_23210	COG0395	ABC-type sugar transport system, permease component
FY148_23215	COG3842	ATPase activity
FY148_23225	COG0673	inositol 2-dehydrogenase activity
FY148_23255	COG0587	DNA-directed DNA polymerase activity
FY148_23260	COG2226	methyltransferase
FY148_23275	COG2186	Transcriptional regulator
FY148_23280	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_23285	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_23290	COG1129	ABC transporter
FY148_23295	COG1879	ABC-type sugar transport system periplasmic component
FY148_23300	COG0129	dihydroxy-acid dehydratase activity
FY148_23310	COG0346	lactoylglutathione lyase activity
FY148_23325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY148_23330	COG4608	Belongs to the ABC transporter superfamily
FY148_23340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_23345	COG0601	transmembrane transport
FY148_23350	COG0747	negative chemotaxis
FY148_23360	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY148_23365	COG5001	Diguanylate cyclase
FY148_23375	COG3257	ureidoglycine aminohydrolase activity
FY148_23385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_23390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY148_23400	COG1129	ABC transporter
FY148_23405	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_23410	COG1879	ABC-type sugar transport system periplasmic component
FY148_23415	COG0583	DNA-binding transcription factor activity
FY148_23440	COG3047	cAMP biosynthetic process
FY148_23450	COG3842	ATPase activity
FY148_23455	COG0395	ABC-type sugar transport system, permease component
FY148_23460	COG1175	transmembrane transport
FY148_23465	COG1653	transport
FY148_23470	COG0523	cobalamin synthesis protein
FY148_23485	COG0523	cobalamin synthesis protein
FY148_23490	COG1121	(ABC) transporter
FY148_23500	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY148_23505	COG0454	-acetyltransferase
FY148_23520	COG0626	cystathionine gamma-synthase activity
FY148_23525	COG2182	Extracellular solute-binding protein
FY148_23535	COG0395	ABC-type sugar transport system, permease component
FY148_23550	COG0395	ABC-type sugar transport system, permease component
FY148_23555	COG1175	transmembrane transport
FY148_23560	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY148_23565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY148_23575	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_23580	COG1063	alcohol dehydrogenase
FY148_23585	COG1609	Transcriptional regulator
FY148_23590	COG2223	nitrite transmembrane transporter activity
FY148_23595	COG4977	sequence-specific DNA binding
FY148_23625	COG0667	Aldo Keto reductase
FY148_23640	COG2186	Transcriptional regulator
FY148_23645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY148_23650	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY148_23655	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_23660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY148_23665	COG4948	Mandelate Racemase Muconate Lactonizing
FY148_23670	COG3618	amidohydrolase
FY148_23680	COG1175	transmembrane transport
FY148_23685	COG0395	ABC-type sugar transport system, permease component
FY148_23690	COG3842	ATPase activity
FY148_23705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY148_23710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY148_23730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY148_23740	COG1278	Cold shock
FY148_23745	COG0673	inositol 2-dehydrogenase activity
FY148_23760	COG0673	inositol 2-dehydrogenase activity
FY148_23765	COG1309	transcriptional regulator
FY148_23770	COG1653	transport
FY148_23775	COG1175	transmembrane transport
FY148_23780	COG0395	ABC-type sugar transport system, permease component
FY148_23785	COG3842	ATPase activity
FY148_23790	COG1082	Xylose isomerase domain protein TIM barrel
FY148_23805	COG1609	Transcriptional regulator
FY148_23835	COG1175	transmembrane transport
FY148_23840	COG0395	ABC-type sugar transport system, permease component
FY148_23845	COG1116	anion transmembrane transporter activity
FY148_23850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY148_23855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY148_23870	COG3842	ATPase activity
FY148_23875	COG0395	ABC-type sugar transport system, permease component
FY148_23885	COG1653	transport
FY148_23920	COG3842	ATPase activity
FY148_23930	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_23935	COG0395	ABC-type sugar transport system, permease component
FY148_23995	COG2233	PERMEase
FY148_24010	COG5002	protein histidine kinase activity
FY148_24015	COG0745	RESPONSE REGULATOR receiver
FY148_24020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY148_24025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY148_24030	COG0702	epimerase
FY148_24040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY148_24075	COG2235	arginine
FY148_24085	COG0628	permease
FY148_24110	COG1522	sequence-specific DNA binding
FY148_24130	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_24145	COG1414	Transcriptional regulator
FY148_24155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY148_24160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY148_24160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY148_24175	COG2140	Oxalate decarboxylase
FY148_24185	COG4566	intracellular signal transduction
FY148_24190	COG4566	intracellular signal transduction
FY148_24200	COG0243	molybdopterin cofactor binding
FY148_24205	COG0783	Belongs to the Dps family
FY148_24220	COG0596	Alpha beta hydrolase
FY148_24230	COG1764	response to oxidative stress
FY148_24245	COG0596	Alpha beta hydrolase
FY148_24255	COG0785	Cytochrome C biogenesis protein
FY148_24255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY148_24280	COG4172	Belongs to the ABC transporter superfamily
FY148_24300	COG0747	negative chemotaxis
FY148_24305	COG0601	transmembrane transport
FY148_24310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_24315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_24325	COG4106	trans-aconitate 2-methyltransferase activity
FY148_24330	COG0025	NhaP-type Na H and K H
FY148_24335	COG4302	ethanolamine ammonia-lyase activity
FY148_24360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY148_24365	COG1349	DNA-binding transcription factor activity
FY148_24370	COG4608	Belongs to the ABC transporter superfamily
FY148_24380	COG0601	transmembrane transport
FY148_24385	COG0747	negative chemotaxis
FY148_24390	COG1454	alcohol dehydrogenase
FY148_24395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY148_24400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY148_24405	COG0411	ABC transporter
FY148_24445	COG1192	Involved in chromosome partitioning
FY148_24450	COG1475	DNA binding
FY148_24455	COG0640	Transcriptional regulator
FY148_24470	COG1126	abc transporter atp-binding protein
FY148_24475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY148_24480	COG1609	Transcriptional regulator
FY148_24515	COG3239	Fatty acid desaturase
FY148_24525	COG1278	Cold shock
FY148_24605	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY148_24605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY148_24640	COG4191	Histidine kinase
FY148_24645	COG1132	(ABC) transporter
FY148_24655	COG0640	Transcriptional regulator
FY148_24685	COG4977	sequence-specific DNA binding
FY148_24690	COG2211	Major facilitator Superfamily
FY148_24695	COG2807	transmembrane transport
FY148_24700	COG1846	Transcriptional regulator
FY148_24715	COG2814	Major facilitator Superfamily
FY148_24745	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY148_24760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY148_24765	COG0583	DNA-binding transcription factor activity
FY148_24780	COG0071	Belongs to the small heat shock protein (HSP20) family
FY148_24825	COG3838	Conjugal transfer protein Trbc
FY148_24830	COG3702	type iv secretory pathway
FY148_24835	COG3451	type IV secretory pathway VirB4
FY148_24850	COG3704	protein secretion by the type IV secretion system
FY148_24860	COG3736	Type IV secretory pathway, component VirB8
FY148_24865	COG3504	Conjugal transfer protein
FY148_24870	COG2948	multi-organism process
FY148_24875	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY148_24975	COG3831	ATPase activity
FY148_24990	COG3505	Type IV secretory pathway VirD4
FY148_25015	COG0583	DNA-binding transcription factor activity
FY148_25055	COG0745	RESPONSE REGULATOR receiver
FY148_25095	COG3842	ATPase activity
FY148_25100	COG4208	sulfate ABC transporter
FY148_25105	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_25125	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY148_25130	COG1942	4-Oxalocrotonate Tautomerase
FY148_25140	COG3971	2-oxopent-4-enoate hydratase activity
FY148_25150	COG1414	Transcriptional regulator
FY148_25160	COG1137	ATPase activity
FY148_25175	COG4177	L-phenylalanine transmembrane transporter activity
FY148_25195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY148_25200	COG1175	transmembrane transport
FY148_25205	COG0395	ABC-type sugar transport system, permease component
FY148_25215	COG0366	Alpha amylase catalytic
FY148_25220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY148_25225	COG1082	Xylose isomerase domain protein TIM barrel
FY148_25230	COG3842	ATPase activity
FY148_25240	COG1940	carbohydrate kinase activity
FY148_25245	COG0395	ABC-type sugar transport system, permease component
FY148_25255	COG2182	Extracellular solute-binding protein
FY148_25260	COG0673	inositol 2-dehydrogenase activity
FY148_25290	COG1126	abc transporter atp-binding protein
FY148_25295	COG0765	amino acid transport
FY148_25300	COG0765	amino acid transport
FY148_25310	COG4608	Belongs to the ABC transporter superfamily
FY148_25320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_25335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY148_25340	COG0583	DNA-binding transcription factor activity
FY148_25345	COG2423	ornithine cyclodeaminase activity
FY148_25355	COG1957	nucleoside hydrolase
FY148_25370	COG1335	isochorismatase
FY148_25375	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_25420	COG0583	DNA-binding transcription factor activity
FY148_25425	COG1902	pentaerythritol trinitrate reductase activity
FY148_25430	COG0583	DNA-binding transcription factor activity
FY148_25435	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_25445	COG1335	isochorismatase
FY148_25450	COG0583	DNA-binding transcription factor activity
FY148_25460	COG1695	Transcriptional regulator
FY148_25540	COG2207	Transcriptional regulator
FY148_25585	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_25600	COG1802	Transcriptional regulator
FY148_25605	COG3485	protocatechuate 3,4-dioxygenase
FY148_25610	COG3971	2-oxopent-4-enoate hydratase activity
FY148_25625	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY148_25630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY148_25645	COG1063	alcohol dehydrogenase
FY148_25655	COG1960	acyl-CoA dehydrogenase activity
FY148_25660	COG1024	Enoyl-CoA hydratase
FY148_25670	COG1012	belongs to the aldehyde dehydrogenase family
FY148_25675	COG0477	Major facilitator Superfamily
FY148_25690	COG3706	GGDEF domain
FY148_25710	COG1846	Transcriptional regulator
FY148_25750	COG1012	belongs to the aldehyde dehydrogenase family
FY148_25760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY148_25770	COG3386	PFAM SMP-30 Gluconolaconase
FY148_25775	COG3622	Belongs to the hyi family
FY148_25780	COG2084	Dehydrogenase
FY148_25805	COG1940	carbohydrate kinase activity
FY148_25810	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_25820	COG1129	ABC transporter
FY148_25840	COG0583	DNA-binding transcription factor activity
FY148_25845	COG2271	Major facilitator Superfamily
FY148_25855	COG2272	Belongs to the type-B carboxylesterase lipase family
FY148_25875	COG1129	ABC transporter
FY148_25900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY148_25910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY148_25945	COG0583	DNA-binding transcription factor activity
FY148_25950	COG1414	Transcriptional regulator
FY148_25960	COG4948	Mandelate Racemase Muconate Lactonizing
FY148_25970	COG3842	ATPase activity
FY148_25975	COG1175	transmembrane transport
FY148_25980	COG0395	ABC-type sugar transport system, permease component
FY148_25990	COG0477	Major facilitator Superfamily
FY148_26025	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY148_26045	COG0747	negative chemotaxis
FY148_26055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_26070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY148_26080	COG4215	(ABC) transporter
FY148_26135	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY148_26140	COG0251	oxidation-reduction process
FY148_26145	COG3547	Transposase (IS116 IS110 IS902 family)
FY148_26180	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_26185	COG1335	isochorismatase
FY148_26195	COG1309	transcriptional regulator
FY148_26200	COG4604	ABC transporter, ATP-binding protein
FY148_26205	COG4605	iron ion homeostasis
FY148_26210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY148_26220	COG2132	Multicopper oxidase
FY148_26225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY148_26230	COG4771	TonB-dependent receptor
FY148_26265	COG1695	Transcriptional regulator
FY148_26300	COG2132	Multicopper oxidase
FY148_26335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY148_26355	COG1192	Involved in chromosome partitioning
FY148_26360	COG1475	DNA binding
FY148_26365	COG0640	Transcriptional regulator
FY148_26370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY148_26400	COG2211	Major facilitator Superfamily
FY148_26450	COG1051	belongs to the nudix hydrolase family
FY148_26490	COG1475	DNA binding
FY148_26515	COG2824	Alkylphosphonate utilization operon protein PhnA
FY148_26535	COG1280	lysine exporter protein (LysE YggA)
FY148_26550	COG5489	Protein of unknown function (DUF736)
FY148_26610	COG1879	ABC-type sugar transport system periplasmic component
FY148_26615	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY148_26635	COG1280	lysine exporter protein (LysE YggA)
FY148_26720	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY148_26735	COG0747	negative chemotaxis
FY148_26740	COG0444	Belongs to the ABC transporter superfamily
FY148_26755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_26760	COG0584	glycerophosphoryl diester phosphodiesterase
FY148_26765	COG0483	inositol monophosphate 1-phosphatase activity
FY148_26830	COG3161	chorismate lyase activity
FY148_26980	COG3436	PFAM IS66 Orf2 family protein
FY148_27060	COG2222	sugar isomerase
FY148_27070	COG0006	proline dipeptidase activity
FY148_27090	COG1177	transmembrane transport
FY148_27095	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY148_27100	COG3842	ATPase activity
FY148_27130	COG3842	ATPase activity
FY148_27135	COG0006	proline dipeptidase activity
FY148_27155	COG0300	oxidoreductase activity
FY148_27160	COG0129	dihydroxy-acid dehydratase activity
FY148_27165	COG0667	Aldo Keto reductase
FY148_27175	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_27185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_27190	COG0601	transmembrane transport
FY148_27195	COG4172	Belongs to the ABC transporter superfamily
FY148_27205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY148_27240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY148_27275	COG3701	Conjugal transfer protein
FY148_27280	COG3846	protein secretion by the type IV secretion system
FY148_27290	COG5314	conjugation
FY148_27295	COG3451	type IV secretory pathway VirB4
FY148_27310	COG4962	Type ii secretion system protein e
FY148_27365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY148_27380	COG0469	pyruvate kinase activity
FY148_27390	COG0574	Belongs to the PEP-utilizing enzyme family
FY148_27390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY148_27400	COG1028	Short-chain dehydrogenase reductase Sdr
FY148_27415	COG1619	proteins homologs of microcin C7 resistance protein MccF
FY148_27425	COG2226	methyltransferase
FY148_27445	COG0495	leucyl-tRNA aminoacylation
FY148_27460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY148_27470	COG1132	(ABC) transporter
FY148_27500	COG1475	DNA binding