locus-tag	class	description
FY149_00010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY149_00040	COG1278	Cold shock
FY149_00075	COG0411	ABC transporter
FY149_00080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY149_00085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY149_00090	COG1454	alcohol dehydrogenase
FY149_00095	COG0747	negative chemotaxis
FY149_00100	COG0601	transmembrane transport
FY149_00110	COG4608	Belongs to the ABC transporter superfamily
FY149_00115	COG1349	DNA-binding transcription factor activity
FY149_00120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_00145	COG4302	ethanolamine ammonia-lyase activity
FY149_00150	COG0025	NhaP-type Na H and K H
FY149_00155	COG4106	trans-aconitate 2-methyltransferase activity
FY149_00165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_00170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_00175	COG0601	transmembrane transport
FY149_00200	COG4172	Belongs to the ABC transporter superfamily
FY149_00235	COG0596	Alpha beta hydrolase
FY149_00250	COG1764	response to oxidative stress
FY149_00260	COG0596	Alpha beta hydrolase
FY149_00275	COG0783	Belongs to the Dps family
FY149_00280	COG0243	molybdopterin cofactor binding
FY149_00290	COG4566	intracellular signal transduction
FY149_00295	COG4566	intracellular signal transduction
FY149_00325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_00335	COG1414	Transcriptional regulator
FY149_00350	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_00370	COG1522	sequence-specific DNA binding
FY149_00395	COG0628	permease
FY149_00405	COG2235	arginine
FY149_00440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_00450	COG0702	epimerase
FY149_00455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_00460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_00465	COG0745	RESPONSE REGULATOR receiver
FY149_00470	COG5002	protein histidine kinase activity
FY149_00485	COG2233	PERMEase
FY149_00545	COG0395	ABC-type sugar transport system, permease component
FY149_00550	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_00560	COG3842	ATPase activity
FY149_00595	COG1653	transport
FY149_00605	COG0395	ABC-type sugar transport system, permease component
FY149_00610	COG3842	ATPase activity
FY149_00625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_00630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_00635	COG1116	anion transmembrane transporter activity
FY149_00640	COG0395	ABC-type sugar transport system, permease component
FY149_00645	COG1175	transmembrane transport
FY149_00675	COG1609	Transcriptional regulator
FY149_00690	COG1082	Xylose isomerase domain protein TIM barrel
FY149_00695	COG3842	ATPase activity
FY149_00700	COG0395	ABC-type sugar transport system, permease component
FY149_00705	COG1175	transmembrane transport
FY149_00710	COG1653	transport
FY149_00715	COG1309	transcriptional regulator
FY149_00720	COG0673	inositol 2-dehydrogenase activity
FY149_00735	COG0673	inositol 2-dehydrogenase activity
FY149_00740	COG1278	Cold shock
FY149_00750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY149_00770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_00775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY149_00790	COG3842	ATPase activity
FY149_00795	COG0395	ABC-type sugar transport system, permease component
FY149_00800	COG1175	transmembrane transport
FY149_00810	COG3618	amidohydrolase
FY149_00815	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_00820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_00825	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_00830	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY149_00835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_00840	COG2186	Transcriptional regulator
FY149_00855	COG0667	Aldo Keto reductase
FY149_00885	COG4977	sequence-specific DNA binding
FY149_00890	COG2223	nitrite transmembrane transporter activity
FY149_00895	COG1609	Transcriptional regulator
FY149_00900	COG1063	alcohol dehydrogenase
FY149_00905	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_00915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_00920	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY149_00925	COG1175	transmembrane transport
FY149_00930	COG0395	ABC-type sugar transport system, permease component
FY149_00945	COG0395	ABC-type sugar transport system, permease component
FY149_00955	COG2182	Extracellular solute-binding protein
FY149_00960	COG0626	cystathionine gamma-synthase activity
FY149_00975	COG0454	-acetyltransferase
FY149_00980	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY149_00990	COG1121	(ABC) transporter
FY149_00995	COG0523	cobalamin synthesis protein
FY149_01010	COG0523	cobalamin synthesis protein
FY149_01015	COG1653	transport
FY149_01020	COG1175	transmembrane transport
FY149_01025	COG0395	ABC-type sugar transport system, permease component
FY149_01030	COG3842	ATPase activity
FY149_01040	COG3047	cAMP biosynthetic process
FY149_01090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY149_01100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_01105	COG0765	amino acid transport
FY149_01110	COG1126	abc transporter atp-binding protein
FY149_01125	COG0793	Belongs to the peptidase S41A family
FY149_01160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY149_01170	COG0406	alpha-ribazole phosphatase activity
FY149_01210	COG3422	double-strand break repair
FY149_01320	COG1280	lysine exporter protein (LysE YggA)
FY149_01415	COG0583	DNA-binding transcription factor activity
FY149_01420	COG1879	ABC-type sugar transport system periplasmic component
FY149_01425	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_01430	COG1129	ABC transporter
FY149_01440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_01445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_01455	COG3257	ureidoglycine aminohydrolase activity
FY149_01465	COG5001	Diguanylate cyclase
FY149_01470	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY149_01480	COG0747	negative chemotaxis
FY149_01485	COG0601	transmembrane transport
FY149_01490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_01500	COG4608	Belongs to the ABC transporter superfamily
FY149_01505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY149_01520	COG0346	lactoylglutathione lyase activity
FY149_01530	COG0129	dihydroxy-acid dehydratase activity
FY149_01535	COG1879	ABC-type sugar transport system periplasmic component
FY149_01540	COG1129	ABC transporter
FY149_01545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_01550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_01555	COG2186	Transcriptional regulator
FY149_01570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY149_01575	COG0587	DNA-directed DNA polymerase activity
FY149_01605	COG0673	inositol 2-dehydrogenase activity
FY149_01615	COG3842	ATPase activity
FY149_01620	COG0395	ABC-type sugar transport system, permease component
FY149_01625	COG1175	transmembrane transport
FY149_01630	COG1653	transport
FY149_01640	COG0673	inositol 2-dehydrogenase activity
FY149_01655	COG5001	Diguanylate cyclase
FY149_01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_01670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY149_01675	COG2894	cell division
FY149_01680	COG0850	regulation of cytokinetic process
FY149_01685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY149_01690	COG2186	Transcriptional regulator
FY149_01695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_01705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY149_01710	COG1063	alcohol dehydrogenase
FY149_01715	COG1312	Catalyzes the dehydration of D-mannonate
FY149_01735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_01740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY149_01740	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY149_01745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_01760	COG0625	glutathione transferase activity
FY149_01765	COG4172	Belongs to the ABC transporter superfamily
FY149_01770	COG1921	L-seryl-tRNASec selenium transferase activity
FY149_01785	COG3964	amidohydrolase
FY149_01795	COG0601	transmembrane transport
FY149_01800	COG0747	negative chemotaxis
FY149_01805	COG0438	transferase activity, transferring glycosyl groups
FY149_01840	COG4989	oxidoreductase activity
FY149_01850	COG2188	Transcriptional regulator
FY149_01855	COG3842	ATPase activity
FY149_01860	COG1653	transport
FY149_01865	COG1175	transmembrane transport
FY149_01870	COG0395	ABC-type sugar transport system, permease component
FY149_01875	COG1501	Belongs to the glycosyl hydrolase 31 family
FY149_01885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_01890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_01895	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY149_01900	COG0352	thiamine-phosphate diphosphorylase activity
FY149_01905	COG0351	phosphomethylpyrimidine kinase
FY149_01910	COG1522	sequence-specific DNA binding
FY149_01915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY149_01920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_01935	COG2204	response regulator
FY149_01940	COG4191	Histidine kinase
FY149_01945	COG1301	dicarboxylic acid transport
FY149_01950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY149_01955	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_01965	COG1473	amidohydrolase
FY149_01985	COG1215	transferase activity, transferring glycosyl groups
FY149_01995	COG2942	2-epimerase
FY149_02020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_02030	COG2197	response regulator
FY149_02060	COG3307	-O-antigen
FY149_02065	COG1596	polysaccharide export
FY149_02070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY149_02080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY149_02085	COG0840	transmembrane signaling receptor activity
FY149_02090	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_02100	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_02110	COG2094	Belongs to the DNA glycosylase MPG family
FY149_02125	COG1609	Transcriptional regulator
FY149_02130	COG1653	transport
FY149_02145	COG3842	ATPase activity
FY149_02155	COG0673	inositol 2-dehydrogenase activity
FY149_02160	COG0602	queuosine metabolic process
FY149_02165	COG0720	synthase
FY149_02170	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY149_02175	COG0673	inositol 2-dehydrogenase activity
FY149_02190	COG0395	ABC-type sugar transport system, permease component
FY149_02195	COG1175	transmembrane transport
FY149_02220	COG0583	DNA-binding transcription factor activity
FY149_02225	COG0280	phosphate acetyltransferase
FY149_02225	COG0281	malic enzyme
FY149_02240	COG0765	amino acid transport
FY149_02245	COG1126	abc transporter atp-binding protein
FY149_02250	COG2079	MmgE PrpD family protein
FY149_02255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_02280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY149_02290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY149_02295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY149_02300	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_02305	COG1129	ABC transporter
FY149_02320	COG1473	amidohydrolase
FY149_02325	COG0747	negative chemotaxis
FY149_02340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_02345	COG0601	transmembrane transport
FY149_02350	COG0583	DNA-binding transcription factor activity
FY149_02355	COG1446	asparaginase
FY149_02370	COG0747	negative chemotaxis
FY149_02390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_02395	COG0601	transmembrane transport
FY149_02400	COG2197	response regulator
FY149_02405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_02410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_02420	COG3842	ATPase activity
FY149_02425	COG0395	ABC-type sugar transport system, permease component
FY149_02430	COG1175	transmembrane transport
FY149_02440	COG0673	inositol 2-dehydrogenase activity
FY149_02445	COG0673	inositol 2-dehydrogenase activity
FY149_02465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_02470	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY149_02490	COG1595	DNA-templated transcription, initiation
FY149_02495	COG1120	ATPase activity
FY149_02500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_02515	COG2226	methyltransferase
FY149_02525	COG1120	ATPase activity
FY149_02530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_02575	COG1012	belongs to the aldehyde dehydrogenase family
FY149_02580	COG0473	3-isopropylmalate dehydrogenase activity
FY149_02585	COG1012	belongs to the aldehyde dehydrogenase family
FY149_02590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_02625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_02630	COG4172	Belongs to the ABC transporter superfamily
FY149_02635	COG1522	sequence-specific DNA binding
FY149_02645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_02660	COG0583	DNA-binding transcription factor activity
FY149_02670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_02675	COG1126	abc transporter atp-binding protein
FY149_02685	COG1473	amidohydrolase
FY149_02690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02700	COG1959	2 iron, 2 sulfur cluster binding
FY149_02710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY149_02715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02745	COG1960	acyl-CoA dehydrogenase activity
FY149_02755	COG0747	negative chemotaxis
FY149_02770	COG0444	Belongs to the ABC transporter superfamily
FY149_02780	COG0667	Aldo Keto reductase
FY149_02790	COG0583	DNA-binding transcription factor activity
FY149_02795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02800	COG4166	transmembrane transport
FY149_02815	COG0747	negative chemotaxis
FY149_02820	COG1473	amidohydrolase
FY149_02825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_02855	COG1733	regulation of RNA biosynthetic process
FY149_02860	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_02995	COG4373	Mu-like prophage FluMu protein gp28
FY149_03000	COG4383	Mu-like prophage protein gp29
FY149_03005	COG2369	cell adhesion
FY149_03135	COG4608	Belongs to the ABC transporter superfamily
FY149_03140	COG0444	Belongs to the ABC transporter superfamily
FY149_03150	COG0601	transmembrane transport
FY149_03160	COG2186	Transcriptional regulator
FY149_03175	COG0300	oxidoreductase activity
FY149_03185	COG3453	Protein conserved in bacteria
FY149_03185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY149_03190	COG0640	Transcriptional regulator
FY149_03200	COG2391	methyltransferase activity
FY149_03205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY149_03215	COG0022	dehydrogenase e1 component
FY149_03225	COG1960	acyl-CoA dehydrogenase activity
FY149_03230	COG0183	Belongs to the thiolase family
FY149_03240	COG1960	acyl-CoA dehydrogenase activity
FY149_03245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY149_03265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY149_03270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY149_03275	COG4952	isomerase
FY149_03280	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_03280	COG3347	Dehydrogenase
FY149_03285	COG1349	DNA-binding transcription factor activity
FY149_03295	COG1129	ABC transporter
FY149_03300	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_03305	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_03310	COG3254	rhamnose metabolic process
FY149_03325	COG2264	protein methyltransferase activity
FY149_03330	COG5001	Diguanylate cyclase
FY149_03345	COG4335	DNA alkylation repair
FY149_03350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY149_03355	COG4208	sulfate ABC transporter
FY149_03365	COG4150	thiosulfate binding
FY149_03370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY149_03385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY149_03395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY149_03405	COG1040	competence protein
FY149_03410	COG2226	methyltransferase
FY149_03425	COG0494	nUDIX hydrolase
FY149_03435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY149_03440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY149_03445	COG0653	protein targeting
FY149_03450	COG0697	spore germination
FY149_03515	COG2244	polysaccharide biosynthetic process
FY149_03530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY149_03540	COG3206	protein involved in exopolysaccharide biosynthesis
FY149_03540	COG0489	protein tyrosine kinase activity
FY149_03560	COG0438	transferase activity, transferring glycosyl groups
FY149_03565	COG0438	transferase activity, transferring glycosyl groups
FY149_03580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY149_03585	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY149_03585	COG2273	Hydrolase Family 16
FY149_03600	COG3842	ATPase activity
FY149_03605	COG3833	ABC-type maltose transport systems, permease component
FY149_03660	COG1396	sequence-specific DNA binding
FY149_03670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY149_03675	COG1129	ABC transporter
FY149_03680	COG4214	carbohydrate transport
FY149_03685	COG4213	ABC transporter substrate-binding protein
FY149_03700	COG0346	lactoylglutathione lyase activity
FY149_03705	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY149_03705	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY149_03710	COG4770	biotin carboxylase activity
FY149_03725	COG0625	glutathione transferase activity
FY149_03730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY149_03735	COG1396	sequence-specific DNA binding
FY149_03735	COG3800	Transcriptional regulator
FY149_03745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY149_03755	COG0300	oxidoreductase activity
FY149_03765	COG2096	Adenosyltransferase
FY149_03775	COG2086	electron transfer activity
FY149_03785	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY149_03795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY149_03800	COG0165	Argininosuccinate lyase
FY149_03835	COG2884	Cell division ATP-binding protein ftsE
FY149_03855	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY149_03865	COG0287	Prephenate dehydrogenase
FY149_03870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY149_03875	COG2226	methyltransferase
FY149_03880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY149_03900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY149_03905	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY149_03945	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY149_03950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY149_03960	COG4974	Belongs to the 'phage' integrase family
FY149_03965	COG0825	malonyl-CoA metabolic process
FY149_03970	COG3034	peptidoglycan biosynthetic process
FY149_03975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY149_03975	COG0425	Belongs to the sulfur carrier protein TusA family
FY149_03980	COG0523	cobalamin synthesis protein
FY149_03985	COG1686	Belongs to the peptidase S11 family
FY149_03990	COG1473	amidohydrolase
FY149_04000	COG4953	penicillin-binding protein 1C
FY149_04005	COG2373	Large extracellular alpha-helical protein
FY149_04010	COG2835	tetraacyldisaccharide 4'-kinase activity
FY149_04040	COG0482	sulfurtransferase activity
FY149_04055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY149_04070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY149_04075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY149_04080	COG0037	tRNA processing
FY149_04090	COG2885	chlorophyll binding
FY149_04095	COG0823	Involved in the tonB-independent uptake of proteins
FY149_04115	COG0824	Thioesterase
FY149_04125	COG0494	nUDIX hydrolase
FY149_04140	COG2255	four-way junction helicase activity
FY149_04145	COG0632	four-way junction helicase activity
FY149_04150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY149_04155	COG0840	transmembrane signaling receptor activity
FY149_04160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_04165	COG0217	transcriptional regulatory protein
FY149_04180	COG1692	metallophosphoesterase
FY149_04190	COG1253	flavin adenine dinucleotide binding
FY149_04230	COG0126	phosphoglycerate kinase activity
FY149_04235	COG3588	fructose-bisphosphate aldolase
FY149_04255	COG0254	rRNA binding
FY149_04260	COG1132	(ABC) transporter
FY149_04280	COG0483	inositol monophosphate 1-phosphatase activity
FY149_04310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY149_04315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY149_04320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY149_04325	COG0457	Tetratricopeptide repeat
FY149_04330	COG3750	Belongs to the UPF0335 family
FY149_04350	COG0469	pyruvate kinase activity
FY149_04355	COG3108	Peptidase M15
FY149_04360	COG2204	response regulator
FY149_04365	COG1164	Oligoendopeptidase f
FY149_04370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY149_04380	COG5310	Homospermidine synthase
FY149_04390	COG0737	Belongs to the 5'-nucleotidase family
FY149_04395	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY149_04400	COG0330	HflC and HflK could
FY149_04425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY149_04430	COG2951	lytic endotransglycosylase activity
FY149_04445	COG2205	protein histidine kinase activity
FY149_04460	COG0069	glutamate synthase activity
FY149_04460	COG0067	glutamate synthase
FY149_04460	COG0070	glutamate synthase
FY149_04475	COG2205	protein histidine kinase activity
FY149_04480	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY149_04485	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY149_04490	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY149_04500	COG0252	asparaginase activity
FY149_04510	COG1027	Aspartate ammonia-lyase
FY149_04515	COG2186	Transcriptional regulator
FY149_04555	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_04560	COG4175	Glycine betaine
FY149_04560	COG0517	IMP dehydrogenase activity
FY149_04565	COG2986	histidine ammonia-lyase
FY149_04570	COG1609	Transcriptional regulator
FY149_04590	COG1082	Xylose isomerase domain protein TIM barrel
FY149_04595	COG0673	inositol 2-dehydrogenase activity
FY149_04600	COG1082	Xylose isomerase domain protein TIM barrel
FY149_04625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY149_04670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_04680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_04685	COG0601	transmembrane transport
FY149_04690	COG0747	negative chemotaxis
FY149_04700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY149_04705	COG1454	alcohol dehydrogenase
FY149_04745	COG2308	Evidence 4 Homologs of previously reported genes of
FY149_04745	COG2307	Protein conserved in bacteria
FY149_04760	COG0488	(ABC) transporter
FY149_04765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_04770	COG2186	Transcriptional regulator
FY149_04785	COG1175	transmembrane transport
FY149_04790	COG0395	ABC-type sugar transport system, permease component
FY149_04800	COG3842	ATPase activity
FY149_04825	COG1304	FMN binding
FY149_04840	COG1063	alcohol dehydrogenase
FY149_04845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_04850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_04860	COG0765	amino acid transport
FY149_04865	COG0765	amino acid transport
FY149_04870	COG4221	oxidoreductase activity
FY149_04875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_04880	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_04885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_04900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_04915	COG0697	spore germination
FY149_04920	COG0697	spore germination
FY149_04925	COG0511	ligase activity, forming carbon-carbon bonds
FY149_04930	COG0439	Biotin carboxylase
FY149_04940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_04945	COG1984	allophanate hydrolase subunit 2
FY149_04950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_04955	COG3842	ATPase activity
FY149_04965	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY149_04975	COG0436	Aminotransferase
FY149_04990	COG0840	transmembrane signaling receptor activity
FY149_04995	COG1070	Carbohydrate kinase
FY149_05000	COG1830	Aldolase
FY149_05005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY149_05010	COG0667	Aldo Keto reductase
FY149_05020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_05025	COG1129	ABC transporter
FY149_05030	COG1879	ABC-type sugar transport system periplasmic component
FY149_05075	COG0071	Belongs to the small heat shock protein (HSP20) family
FY149_05090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY149_05105	COG0395	ABC-type sugar transport system, permease component
FY149_05120	COG3842	ATPase activity
FY149_05135	COG1648	precorrin-2 dehydrogenase activity
FY149_05135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY149_05140	COG0243	molybdopterin cofactor binding
FY149_05150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY149_05155	COG1116	anion transmembrane transporter activity
FY149_05160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_05165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_05175	COG3707	response regulator
FY149_05180	COG1802	Transcriptional regulator
FY149_05185	COG1914	H( )-stimulated, divalent metal cation uptake system
FY149_05190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_05195	COG4336	lyase activity
FY149_05200	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY149_05205	COG4770	biotin carboxylase activity
FY149_05210	COG0366	Alpha amylase catalytic
FY149_05220	COG4771	TonB-dependent receptor
FY149_05225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY149_05245	COG1414	Transcriptional regulator
FY149_05250	COG1475	DNA binding
FY149_05255	COG1192	Involved in chromosome partitioning
FY149_05285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY149_05295	COG2986	histidine ammonia-lyase
FY149_05300	COG1228	amidohydrolase
FY149_05305	COG0402	S-adenosylhomocysteine deaminase activity
FY149_05345	COG4172	Belongs to the ABC transporter superfamily
FY149_05350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_05355	COG0601	transmembrane transport
FY149_05360	COG4166	transmembrane transport
FY149_05365	COG0395	ABC-type sugar transport system, permease component
FY149_05385	COG1566	PFAM secretion protein HlyD family protein
FY149_05400	COG2207	Transcriptional regulator
FY149_05405	COG1309	transcriptional regulator
FY149_05410	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_05435	COG1846	Transcriptional regulator
FY149_05440	COG0583	DNA-binding transcription factor activity
FY149_05445	COG2828	Protein conserved in bacteria
FY149_05460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_05475	COG0840	transmembrane signaling receptor activity
FY149_05495	COG1215	transferase activity, transferring glycosyl groups
FY149_05525	COG0583	DNA-binding transcription factor activity
FY149_05530	COG0346	lactoylglutathione lyase activity
FY149_05545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY149_05565	COG0583	DNA-binding transcription factor activity
FY149_05570	COG0477	Major facilitator Superfamily
FY149_05580	COG2205	protein histidine kinase activity
FY149_05585	COG0745	RESPONSE REGULATOR receiver
FY149_05590	COG0671	phosphoesterase, PA-phosphatase related
FY149_05640	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY149_05645	COG0156	8-amino-7-oxononanoate synthase activity
FY149_05650	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY149_05655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY149_05660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY149_05675	COG0010	Belongs to the arginase family
FY149_05685	COG0697	spore germination
FY149_05690	COG0673	inositol 2-dehydrogenase activity
FY149_05715	COG0477	Major facilitator Superfamily
FY149_05730	COG2194	sulfuric ester hydrolase activity
FY149_05740	COG0583	DNA-binding transcription factor activity
FY149_05745	COG4774	siderophore transport
FY149_05760	COG1120	ATPase activity
FY149_05770	COG3474	cytochrome
FY149_05775	COG2137	regulation of response to DNA damage stimulus
FY149_05780	COG3386	PFAM SMP-30 Gluconolaconase
FY149_05790	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_05795	COG1129	ABC transporter
FY149_05800	COG1879	ABC-type sugar transport system periplasmic component
FY149_05805	COG4585	Histidine kinase
FY149_05810	COG2197	response regulator
FY149_05820	COG2133	pyrroloquinoline quinone binding
FY149_05830	COG0500	methyltransferase
FY149_05835	COG0564	pseudouridine synthase activity
FY149_05850	COG3448	diguanylate cyclase activity
FY149_05850	COG4175	Glycine betaine
FY149_05855	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_05870	COG0784	Response regulator, receiver
FY149_05870	COG4191	Histidine kinase
FY149_05875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY149_05880	COG0489	protein tyrosine kinase activity
FY149_05880	COG3206	protein involved in exopolysaccharide biosynthesis
FY149_05885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY149_05890	COG1215	transferase activity, transferring glycosyl groups
FY149_05895	COG1215	transferase activity, transferring glycosyl groups
FY149_05900	COG1215	transferase activity, transferring glycosyl groups
FY149_05905	COG0438	transferase activity, transferring glycosyl groups
FY149_05910	COG2273	Hydrolase Family 16
FY149_05915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY149_05920	COG2244	polysaccharide biosynthetic process
FY149_05925	COG0463	Glycosyl transferase, family 2
FY149_05930	COG2327	Polysaccharide pyruvyl transferase
FY149_05935	COG1215	transferase activity, transferring glycosyl groups
FY149_05955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY149_05960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_05975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_05975	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_06005	COG1523	belongs to the glycosyl hydrolase 13 family
FY149_06010	COG0033	Phosphoglucomutase
FY149_06015	COG0297	glycogen (starch) synthase activity
FY149_06020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY149_06025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY149_06030	COG0058	SHG alpha-glucan phosphorylase activity
FY149_06045	COG1794	racemase activity, acting on amino acids and derivatives
FY149_06050	COG1522	sequence-specific DNA binding
FY149_06060	COG2084	Dehydrogenase
FY149_06065	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_06070	COG1063	alcohol dehydrogenase
FY149_06080	COG4988	ABC transporter
FY149_06085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY149_06095	COG1294	oxidase, subunit
FY149_06125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY149_06130	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY149_06160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY149_06165	COG0539	negative regulation of cytoplasmic translation
FY149_06195	COG4221	oxidoreductase activity
FY149_06205	COG0747	negative chemotaxis
FY149_06210	COG0601	transmembrane transport
FY149_06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_06220	COG0444	Belongs to the ABC transporter superfamily
FY149_06225	COG4608	Belongs to the ABC transporter superfamily
FY149_06230	COG0246	Mannitol dehydrogenase
FY149_06245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_06290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY149_06295	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_06310	COG4993	Dehydrogenase
FY149_06315	COG3685	Protein conserved in bacteria
FY149_06345	COG0693	protein deglycase activity
FY149_06365	COG0189	ligase activity
FY149_06370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_06375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY149_06390	COG0435	Glutathione S-transferase
FY149_06395	COG0583	DNA-binding transcription factor activity
FY149_06400	COG1012	belongs to the aldehyde dehydrogenase family
FY149_06405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_06410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_06415	COG1116	anion transmembrane transporter activity
FY149_06425	COG1522	sequence-specific DNA binding
FY149_06440	COG0784	Response regulator, receiver
FY149_06460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY149_06475	COG0019	diaminopimelate decarboxylase activity
FY149_06490	COG0527	aspartate kinase activity
FY149_06500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY149_06505	COG2890	protein-(glutamine-N5) methyltransferase activity
FY149_06515	COG0542	response to heat
FY149_06520	COG0739	heme binding
FY149_06520	COG0741	lytic transglycosylase activity
FY149_06520	COG1196	nuclear chromosome segregation
FY149_06565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY149_06575	COG1280	lysine exporter protein (LysE YggA)
FY149_06590	COG1309	transcriptional regulator
FY149_06595	COG4221	oxidoreductase activity
FY149_06600	COG1902	pentaerythritol trinitrate reductase activity
FY149_06605	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_06645	COG1278	Cold shock
FY149_06665	COG0753	catalase activity
FY149_06690	COG3920	Histidine kinase
FY149_06695	COG1280	lysine exporter protein (LysE YggA)
FY149_06715	COG0583	DNA-binding transcription factor activity
FY149_06750	COG0583	DNA-binding transcription factor activity
FY149_06760	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_06765	COG1846	Transcriptional regulator
FY149_06785	COG2186	Transcriptional regulator
FY149_06795	COG1126	abc transporter atp-binding protein
FY149_06805	COG0765	amino acid transport
FY149_06810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_06825	COG0436	Aminotransferase
FY149_06830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_06860	COG0405	Gamma-glutamyltransferase
FY149_06870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY149_06875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_06880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_06890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_06895	COG0747	negative chemotaxis
FY149_06900	COG0747	negative chemotaxis
FY149_06910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_06920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_06930	COG1129	ABC transporter
FY149_06935	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_06940	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_06965	COG0667	Aldo Keto reductase
FY149_06980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_06985	COG1129	ABC transporter
FY149_06990	COG4213	ABC transporter substrate-binding protein
FY149_07010	COG4608	Belongs to the ABC transporter superfamily
FY149_07015	COG0444	Belongs to the ABC transporter superfamily
FY149_07020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_07025	COG0601	transmembrane transport
FY149_07030	COG0747	negative chemotaxis
FY149_07055	COG0765	amino acid transport
FY149_07060	COG4597	amino acid ABC transporter
FY149_07065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_07080	COG3177	Filamentation induced by cAMP protein fic
FY149_07105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_07135	COG3209	COG3209 Rhs family protein
FY149_07155	COG0745	RESPONSE REGULATOR receiver
FY149_07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_07170	COG1136	(ABC) transporter
FY149_07170	COG0577	efflux transmembrane transporter activity
FY149_07180	COG1733	regulation of RNA biosynthetic process
FY149_07215	COG0534	Mate efflux family protein
FY149_07230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY149_07235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY149_07245	COG1566	PFAM secretion protein HlyD family protein
FY149_07255	COG0625	glutathione transferase activity
FY149_07260	COG4221	oxidoreductase activity
FY149_07270	COG2376	Dihydroxyacetone kinase
FY149_07275	COG1522	sequence-specific DNA binding
FY149_07295	COG0431	NADPH-dependent FMN reductase
FY149_07305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_07315	COG4172	Belongs to the ABC transporter superfamily
FY149_07320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_07340	COG0277	FAD linked oxidase domain protein
FY149_07360	COG0778	Nitroreductase
FY149_07390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_07420	COG2318	DinB family
FY149_07425	COG0583	DNA-binding transcription factor activity
FY149_07440	COG1335	isochorismatase
FY149_07465	COG3842	ATPase activity
FY149_07470	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_07475	COG1177	transmembrane transport
FY149_07480	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY149_07490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY149_07505	COG1120	ATPase activity
FY149_07510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_07515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_07520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY149_07525	COG1629	transport
FY149_07525	COG4774	siderophore transport
FY149_07530	COG4702	Belongs to the UPF0303 family
FY149_07550	COG1024	Enoyl-CoA hydratase
FY149_07555	COG1012	belongs to the aldehyde dehydrogenase family
FY149_07560	COG1653	transport
FY149_07565	COG1175	transmembrane transport
FY149_07570	COG0395	ABC-type sugar transport system, permease component
FY149_07575	COG3842	ATPase activity
FY149_07605	COG3474	cytochrome
FY149_07610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY149_07615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY149_07620	COG1845	cytochrome c oxidase, subunit III
FY149_07645	COG0577	efflux transmembrane transporter activity
FY149_07645	COG1136	(ABC) transporter
FY149_07700	COG3842	ATPase activity
FY149_07710	COG1177	transmembrane transport
FY149_07715	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_07730	COG1940	carbohydrate kinase activity
FY149_07750	COG1069	ribulokinase activity
FY149_07755	COG1349	DNA-binding transcription factor activity
FY149_07760	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_07785	COG0395	ABC-type sugar transport system, permease component
FY149_07795	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_07810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY149_07815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY149_07825	COG0477	Major facilitator Superfamily
FY149_07875	COG1733	regulation of RNA biosynthetic process
FY149_07910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY149_07915	COG3938	Belongs to the proline racemase family
FY149_07920	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_07930	COG4175	Glycine betaine
FY149_07930	COG3448	diguanylate cyclase activity
FY149_07940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_07945	COG1012	belongs to the aldehyde dehydrogenase family
FY149_07950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_07960	COG0047	phosphoribosylformylglycinamidine synthase activity
FY149_07965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_07975	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_07975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_07985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY149_08005	COG1309	transcriptional regulator
FY149_08020	COG1136	(ABC) transporter
FY149_08035	COG1063	alcohol dehydrogenase
FY149_08045	COG1879	ABC-type sugar transport system periplasmic component
FY149_08055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_08075	COG0477	Major facilitator Superfamily
FY149_08205	COG3300	MHYT domain
FY149_08205	COG5001	Diguanylate cyclase
FY149_08230	COG1253	flavin adenine dinucleotide binding
FY149_08245	COG3842	ATPase activity
FY149_08250	COG0395	ABC-type sugar transport system, permease component
FY149_08255	COG1175	transmembrane transport
FY149_08260	COG1653	transport
FY149_08270	COG0673	inositol 2-dehydrogenase activity
FY149_08275	COG1609	Transcriptional regulator
FY149_08290	COG0583	DNA-binding transcription factor activity
FY149_08300	COG1879	ABC-type sugar transport system periplasmic component
FY149_08305	COG1129	ABC transporter
FY149_08310	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_08315	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_08320	COG1609	Transcriptional regulator
FY149_08330	COG0673	inositol 2-dehydrogenase activity
FY149_08390	COG0714	Associated with various cellular activities
FY149_08395	COG3256	nitric oxide reductase
FY149_08425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY149_08430	COG3189	MarR family transcriptional regulator
FY149_08440	COG0826	peptidase U32
FY149_08475	COG4459	periplasmic nitrate reductase
FY149_08490	COG0243	molybdopterin cofactor binding
FY149_08500	COG3005	denitrification pathway
FY149_08515	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_08520	COG1535	isochorismatase
FY149_08520	COG3433	isochorismatase activity
FY149_08525	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY149_08530	COG1169	isochorismate synthase
FY149_08540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY149_08540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY149_08545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY149_08555	COG2375	cellular response to nickel ion
FY149_08565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_08570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_08580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_08590	COG1629	transport
FY149_08590	COG4774	siderophore transport
FY149_08595	COG1960	acyl-CoA dehydrogenase activity
FY149_08600	COG0583	DNA-binding transcription factor activity
FY149_08605	COG1609	Transcriptional regulator
FY149_08615	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_08625	COG3842	ATPase activity
FY149_08635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY149_08640	COG0583	DNA-binding transcription factor activity
FY149_08645	COG2814	Major facilitator Superfamily
FY149_08650	COG1473	amidohydrolase
FY149_08665	COG0747	negative chemotaxis
FY149_08670	COG0601	transmembrane transport
FY149_08675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_08680	COG0444	Belongs to the ABC transporter superfamily
FY149_08685	COG4608	Belongs to the ABC transporter superfamily
FY149_08690	COG0583	DNA-binding transcription factor activity
FY149_08695	COG0747	negative chemotaxis
FY149_08705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_08710	COG0154	amidase activity
FY149_08715	COG0693	protein deglycase activity
FY149_08725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_08730	COG0601	transmembrane transport
FY149_08740	COG1473	amidohydrolase
FY149_08745	COG4172	Belongs to the ABC transporter superfamily
FY149_08750	COG2390	Transcriptional regulator
FY149_08760	COG1175	transmembrane transport
FY149_08765	COG0395	ABC-type sugar transport system, permease component
FY149_08815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY149_08835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY149_08840	COG1414	Transcriptional regulator
FY149_08845	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_08855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY149_08860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY149_08865	COG1121	(ABC) transporter
FY149_08870	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY149_08880	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY149_08885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY149_08890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY149_08895	COG3273	potassium ion transport
FY149_08895	COG0471	metal ion transport
FY149_08900	COG1253	flavin adenine dinucleotide binding
FY149_08905	COG1309	transcriptional regulator
FY149_08925	COG1609	Transcriptional regulator
FY149_08930	COG1070	Carbohydrate kinase
FY149_08935	COG2115	Belongs to the xylose isomerase family
FY149_08945	COG0778	Nitroreductase
FY149_08950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY149_08955	COG2011	ABC-type metal ion transport system permease component
FY149_08965	COG3300	MHYT domain
FY149_08965	COG5001	Diguanylate cyclase
FY149_08970	COG1054	Belongs to the UPF0176 family
FY149_08980	COG2954	triphosphatase activity
FY149_08985	COG0800	Aldolase
FY149_09005	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY149_09045	COG0523	cobalamin synthesis protein
FY149_09055	COG1846	Transcriptional regulator
FY149_09060	COG1609	Transcriptional regulator
FY149_09065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_09075	COG3718	enzyme involved in inositol metabolism
FY149_09085	COG3962	Belongs to the TPP enzyme family
FY149_09090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_09105	COG0411	ABC transporter
FY149_09120	COG0683	leucine binding
FY149_09135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_09145	COG0747	negative chemotaxis
FY149_09150	COG4172	Belongs to the ABC transporter superfamily
FY149_09175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY149_09180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY149_09185	COG1126	abc transporter atp-binding protein
FY149_09190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_09195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_09200	COG0765	amino acid transport
FY149_09205	COG0765	amino acid transport
FY149_09210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY149_09215	COG3485	protocatechuate 3,4-dioxygenase
FY149_09220	COG3485	protocatechuate 3,4-dioxygenase
FY149_09225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY149_09235	COG0583	DNA-binding transcription factor activity
FY149_09250	COG1414	Transcriptional regulator
FY149_09260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY149_09265	COG0183	Belongs to the thiolase family
FY149_09270	COG1609	Transcriptional regulator
FY149_09285	COG1082	Xylose isomerase domain protein TIM barrel
FY149_09290	COG0673	inositol 2-dehydrogenase activity
FY149_09300	COG1609	Transcriptional regulator
FY149_09305	COG0395	ABC-type sugar transport system, permease component
FY149_09310	COG1175	transmembrane transport
FY149_09315	COG3842	ATPase activity
FY149_09325	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY149_09345	COG2814	Major facilitator Superfamily
FY149_09350	COG4774	siderophore transport
FY149_09355	COG3712	iron ion homeostasis
FY149_09365	COG1940	carbohydrate kinase activity
FY149_09370	COG0584	glycerophosphoryl diester phosphodiesterase
FY149_09375	COG0300	oxidoreductase activity
FY149_09390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY149_09410	COG0667	Aldo Keto reductase
FY149_09415	COG0583	DNA-binding transcription factor activity
FY149_09425	COG1132	(ABC) transporter
FY149_09440	COG1442	glycosyl transferase family 8
FY149_09440	COG1216	Glycosyl transferase, family 2
FY149_09445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY149_09455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY149_09475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY149_09480	COG3754	Rhamnan synthesis protein F
FY149_09495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY149_09500	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY149_09505	COG1088	dTDP-glucose 4,6-dehydratase activity
FY149_09510	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY149_09515	COG0210	DNA helicase
FY149_09525	COG1609	Transcriptional regulator
FY149_09530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_09530	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_09545	COG0395	ABC-type sugar transport system, permease component
FY149_09550	COG3842	ATPase activity
FY149_09560	COG0444	Belongs to the ABC transporter superfamily
FY149_09565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_09570	COG0601	transmembrane transport
FY149_09575	COG2186	Transcriptional regulator
FY149_09595	COG5001	Diguanylate cyclase
FY149_09595	COG3300	MHYT domain
FY149_09600	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_09610	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY149_09620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY149_09625	COG0306	phosphate transporter
FY149_09630	COG1392	Phosphate transport regulator
FY149_09645	COG1566	PFAM secretion protein HlyD family protein
FY149_09650	COG0745	RESPONSE REGULATOR receiver
FY149_09655	COG2205	protein histidine kinase activity
FY149_09670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY149_09680	COG4774	siderophore transport
FY149_09690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_09695	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_09700	COG1120	ATPase activity
FY149_09705	COG0583	DNA-binding transcription factor activity
FY149_09715	COG3119	arylsulfatase activity
FY149_09720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_09725	COG3842	ATPase activity
FY149_09730	COG0165	Argininosuccinate lyase
FY149_09735	COG0395	ABC-type sugar transport system, permease component
FY149_09740	COG1175	transmembrane transport
FY149_09745	COG2182	Extracellular solute-binding protein
FY149_09750	COG1940	carbohydrate kinase activity
FY149_09775	COG1486	melibiose metabolic process
FY149_09780	COG0747	negative chemotaxis
FY149_09785	COG0601	transmembrane transport
FY149_09790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_09795	COG4172	Belongs to the ABC transporter superfamily
FY149_09800	COG1486	melibiose metabolic process
FY149_09805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_09810	COG0842	Transport permease protein
FY149_09810	COG1129	ABC transporter
FY149_09815	COG0842	Transport permease protein
FY149_09830	COG0784	Response regulator, receiver
FY149_09835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY149_09845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_09850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY149_09865	COG0765	amino acid transport
FY149_09875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_09885	COG3938	Belongs to the proline racemase family
FY149_09900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_09905	COG0765	amino acid transport
FY149_09910	COG0765	amino acid transport
FY149_09920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY149_09935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY149_09955	COG3383	formate dehydrogenase (NAD+) activity
FY149_09965	COG2223	nitrite transmembrane transporter activity
FY149_09970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_09980	COG2186	Transcriptional regulator
FY149_09985	COG0747	negative chemotaxis
FY149_09990	COG0601	transmembrane transport
FY149_09995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_10000	COG4172	Belongs to the ABC transporter superfamily
FY149_10005	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_10015	COG2186	Transcriptional regulator
FY149_10020	COG0747	negative chemotaxis
FY149_10025	COG0601	transmembrane transport
FY149_10030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_10035	COG0405	Gamma-glutamyltransferase
FY149_10045	COG0483	inositol monophosphate 1-phosphatase activity
FY149_10055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY149_10060	COG0395	ABC-type sugar transport system, permease component
FY149_10080	COG3237	CsbD-like
FY149_10090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY149_10095	COG3181	Tripartite tricarboxylate transporter family receptor
FY149_10100	COG5265	(ABC) transporter
FY149_10105	COG0488	(ABC) transporter
FY149_10130	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY149_10135	COG0110	maltose O-acetyltransferase activity
FY149_10145	COG1063	alcohol dehydrogenase
FY149_10150	COG3284	Transcriptional regulator
FY149_10170	COG1129	ABC transporter
FY149_10175	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_10180	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_10190	COG0572	uridine kinase
FY149_10195	COG1082	Xylose isomerase domain protein TIM barrel
FY149_10220	COG4178	(ABC) transporter
FY149_10260	COG0640	Transcriptional regulator
FY149_10285	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY149_10290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY149_10295	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY149_10300	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY149_10305	COG1420	regulation of RNA biosynthetic process
FY149_10310	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY149_10315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY149_10320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY149_10330	COG1137	ATPase activity
FY149_10335	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY149_10345	COG0616	signal peptide processing
FY149_10350	COG0776	regulation of translation
FY149_10360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY149_10365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY149_10370	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY149_10385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY149_10390	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY149_10395	COG0728	peptidoglycan biosynthetic process
FY149_10405	COG0180	Tryptophanyl-tRNA synthetase
FY149_10415	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY149_10420	COG1214	PFAM Peptidase M22, glycoprotease
FY149_10440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY149_10445	COG1702	phosphate starvation-inducible protein PhoH
FY149_10450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY149_10460	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY149_10465	COG1396	sequence-specific DNA binding
FY149_10470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY149_10475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY149_10480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_10490	COG0242	peptide deformylase activity
FY149_10495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY149_10500	COG0101	tRNA pseudouridine synthase activity
FY149_10510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_10515	COG2171	N-acyltransferase activity
FY149_10525	COG0840	transmembrane signaling receptor activity
FY149_10530	COG1957	nucleoside hydrolase
FY149_10535	COG0071	Belongs to the small heat shock protein (HSP20) family
FY149_10560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY149_10570	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY149_10575	COG0706	membrane insertase activity
FY149_10580	COG0594	ribonuclease P activity
FY149_10585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY149_10590	COG0840	transmembrane signaling receptor activity
FY149_10605	COG2226	methyltransferase
FY149_10610	COG3842	ATPase activity
FY149_10615	COG1175	transmembrane transport
FY149_10620	COG0395	ABC-type sugar transport system, permease component
FY149_10635	COG0427	acetyl-CoA hydrolase
FY149_10645	COG3938	Belongs to the proline racemase family
FY149_10650	COG0418	dihydroorotase activity
FY149_10655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY149_10675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY149_10680	COG0166	Belongs to the GPI family
FY149_10685	COG0318	PFAM AMP-dependent synthetase and ligase
FY149_10690	COG3842	ATPase activity
FY149_10695	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_10700	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY149_10705	COG4774	siderophore transport
FY149_10750	COG2326	polyphosphate kinase activity
FY149_10755	COG5002	protein histidine kinase activity
FY149_10760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY149_10765	COG0573	inorganic phosphate transmembrane transporter activity
FY149_10775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY149_10780	COG0704	Plays a role in the regulation of phosphate uptake
FY149_10785	COG0745	RESPONSE REGULATOR receiver
FY149_10795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY149_10800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY149_10810	COG2967	ApaG domain
FY149_10825	COG0717	Belongs to the dCTP deaminase family
FY149_10835	COG0582	viral genome integration into host DNA
FY149_10860	COG0419	ATPase involved in DNA repair
FY149_10880	COG1396	sequence-specific DNA binding
FY149_10920	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY149_10925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY149_10975	COG0167	dihydroorotate dehydrogenase activity
FY149_11010	COG1959	2 iron, 2 sulfur cluster binding
FY149_11015	COG1201	RNA secondary structure unwinding
FY149_11045	COG1960	acyl-CoA dehydrogenase activity
FY149_11050	COG0183	Belongs to the thiolase family
FY149_11055	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY149_11055	COG1024	Enoyl-CoA hydratase
FY149_11080	COG1320	monovalent cation:proton antiporter activity
FY149_11085	COG2212	antiporter activity
FY149_11090	COG1863	multisubunit Na H antiporter MnhE subunit
FY149_11095	COG0651	ATP synthesis coupled electron transport
FY149_11100	COG1006	Multisubunit Na H antiporter MnhC subunit
FY149_11105	COG2111	Na H antiporter
FY149_11105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY149_11115	COG0840	transmembrane signaling receptor activity
FY149_11125	COG0745	RESPONSE REGULATOR receiver
FY149_11130	COG0643	Histidine kinase
FY149_11130	COG2198	Histidine kinase
FY149_11135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY149_11140	COG2201	protein-glutamate methylesterase activity
FY149_11145	COG0745	RESPONSE REGULATOR receiver
FY149_11150	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY149_11160	COG1766	The M ring may be actively involved in energy transduction
FY149_11165	COG2771	luxR family
FY149_11175	COG0840	transmembrane signaling receptor activity
FY149_11175	COG2972	Histidine kinase
FY149_11180	COG2198	Histidine kinase
FY149_11180	COG0784	Response regulator, receiver
FY149_11180	COG2205	protein histidine kinase activity
FY149_11185	COG1970	mechanosensitive ion channel activity
FY149_11190	COG0436	Aminotransferase
FY149_11205	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY149_11210	COG0424	maF-like protein
FY149_11215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY149_11225	COG5328	Belongs to the UPF0262 family
FY149_11230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY149_11240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY149_11260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY149_11270	COG1338	Plays a role in the flagellum-specific transport system
FY149_11280	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY149_11290	COG1706	bacterial-type flagellum-dependent cell motility
FY149_11295	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY149_11300	COG4786	Flagellar basal body rod
FY149_11305	COG1677	Flagellar hook-basal body complex protein FliE
FY149_11310	COG1558	bacterial-type flagellum-dependent cell motility
FY149_11315	COG1815	bacterial-type flagellum-dependent cell motility
FY149_11325	COG1157	protein secretion by the type III secretion system
FY149_11330	COG4786	Flagellar basal body rod
FY149_11340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY149_11345	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY149_11350	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY149_11355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY149_11360	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY149_11380	COG1360	Flagellar Motor Protein
FY149_11425	COG5443	negative regulation of bacterial-type flagellum assembly
FY149_11430	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY149_11440	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY149_11480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY149_11485	COG1609	Transcriptional regulator
FY149_11490	COG1653	transport
FY149_11495	COG1175	transmembrane transport
FY149_11500	COG0395	ABC-type sugar transport system, permease component
FY149_11505	COG0366	Alpha amylase catalytic
FY149_11510	COG3842	ATPase activity
FY149_11525	COG0129	dihydroxy-acid dehydratase activity
FY149_11530	COG0363	glucosamine-6-phosphate deaminase activity
FY149_11535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY149_11540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_11550	COG2081	HI0933 family
FY149_11570	COG2224	Isocitrate lyase
FY149_11585	COG3842	ATPase activity
FY149_11590	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_11595	COG1177	transmembrane transport
FY149_11610	COG2205	protein histidine kinase activity
FY149_11620	COG0248	Ppx GppA phosphatase
FY149_11625	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY149_11630	COG0477	Major facilitator Superfamily
FY149_11660	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY149_11665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY149_11675	COG0142	geranyltranstransferase activity
FY149_11700	COG0752	glycyl-tRNA synthetase alpha subunit
FY149_11710	COG1704	LemA family
FY149_11715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY149_11725	COG0751	glycine-tRNA ligase activity
FY149_11730	COG1683	Conserved Protein
FY149_11735	COG0840	transmembrane signaling receptor activity
FY149_11745	COG0151	Belongs to the GarS family
FY149_11750	COG2183	response to ionizing radiation
FY149_11755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY149_11780	COG0583	DNA-binding transcription factor activity
FY149_11800	COG0306	phosphate transporter
FY149_11810	COG0561	phosphatase activity
FY149_11815	COG0438	transferase activity, transferring glycosyl groups
FY149_11820	COG2186	Transcriptional regulator
FY149_11830	COG0583	DNA-binding transcription factor activity
FY149_11835	COG0277	FAD linked oxidase domain protein
FY149_11840	COG0277	FAD linked oxidase domain protein
FY149_11845	COG0247	lactate metabolic process
FY149_11855	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_11860	COG2818	Glycosylase
FY149_11870	COG2855	membrane
FY149_11875	COG0583	DNA-binding transcription factor activity
FY149_11905	COG0124	histidyl-tRNA synthetase
FY149_11915	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY149_11920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY149_11925	COG2259	Doxx family
FY149_11935	COG0459	protein refolding
FY149_11940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY149_11950	COG0196	riboflavin kinase activity
FY149_11955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY149_11965	COG0590	tRNA wobble adenosine to inosine editing
FY149_11970	COG1187	pseudouridine synthase activity
FY149_11975	COG0742	ribosomal rna small subunit methyltransferase
FY149_11980	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY149_11990	COG0312	modulator of DNA gyrase
FY149_11995	COG0483	inositol monophosphate 1-phosphatase activity
FY149_12005	COG1519	Transferase
FY149_12015	COG1663	tetraacyldisaccharide 4'-kinase activity
FY149_12025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY149_12030	COG0745	RESPONSE REGULATOR receiver
FY149_12035	COG5001	Diguanylate cyclase
FY149_12035	COG3300	MHYT domain
FY149_12040	COG3386	PFAM SMP-30 Gluconolaconase
FY149_12045	COG0800	Aldolase
FY149_12050	COG3734	2-keto-3-deoxy-galactonokinase
FY149_12055	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_12060	COG1414	Transcriptional regulator
FY149_12065	COG2197	response regulator
FY149_12080	COG0598	Magnesium transport protein CorA
FY149_12085	COG3158	transport of potassium into the cell
FY149_12100	COG0356	it plays a direct role in the translocation of protons across the membrane
FY149_12110	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY149_12115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY149_12130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY149_12150	COG0009	L-threonylcarbamoyladenylate synthase
FY149_12160	COG4638	Rieske (2fe-2S)
FY149_12185	COG1960	acyl-CoA dehydrogenase activity
FY149_12200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY149_12205	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY149_12210	COG0840	transmembrane signaling receptor activity
FY149_12220	COG1522	sequence-specific DNA binding
FY149_12245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY149_12250	COG1741	Belongs to the pirin family
FY149_12255	COG1722	exodeoxyribonuclease VII activity
FY149_12260	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY149_12265	COG1268	BioY protein
FY149_12270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY149_12275	COG1122	ATPase activity
FY149_12280	COG3214	Protein conserved in bacteria
FY149_12285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY149_12285	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY149_12290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY149_12310	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY149_12325	COG0259	pyridoxamine-phosphate oxidase activity
FY149_12355	COG0312	modulator of DNA gyrase
FY149_12370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY149_12375	COG0109	protoheme IX farnesyltransferase activity
FY149_12380	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY149_12395	COG3346	SURF1 family
FY149_12400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY149_12405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY149_12410	COG0328	RNA-DNA hybrid ribonuclease activity
FY149_12420	COG0678	peroxiredoxin activity
FY149_12420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY149_12430	COG1678	Uncharacterized ACR, COG1678
FY149_12435	COG3237	CsbD-like
FY149_12445	COG3300	MHYT domain
FY149_12445	COG5001	Diguanylate cyclase
FY149_12450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY149_12455	COG0612	Peptidase, M16
FY149_12480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY149_12485	COG1802	Transcriptional regulator
FY149_12500	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY149_12505	COG3609	addiction module antidote protein, CC2985 family
FY149_12510	COG3668	Plasmid stabilization system
FY149_12520	COG1194	a g-specific adenine glycosylase
FY149_12535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY149_12540	COG1196	nuclear chromosome segregation
FY149_12545	COG2514	catechol 2,3-dioxygenase activity
FY149_12550	COG0574	Belongs to the PEP-utilizing enzyme family
FY149_12550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY149_12560	COG1823	symporter activity
FY149_12585	COG0579	oxidoreductase
FY149_12600	COG2895	sulfate adenylyltransferase (ATP) activity
FY149_12605	COG0175	sulfate reduction
FY149_12610	COG0175	sulfate reduction
FY149_12615	COG1959	2 iron, 2 sulfur cluster binding
FY149_12620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY149_12625	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY149_12630	COG4208	sulfate ABC transporter
FY149_12635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY149_12645	COG2199	diguanylate cyclase activity
FY149_12645	COG2203	Gaf domain
FY149_12645	COG2200	EAL domain
FY149_12655	COG1309	transcriptional regulator
FY149_12660	COG1012	belongs to the aldehyde dehydrogenase family
FY149_12665	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY149_12695	COG0625	glutathione transferase activity
FY149_12705	COG0477	Major facilitator Superfamily
FY149_12715	COG3657	addiction module killer protein
FY149_12725	COG1793	dna ligase
FY149_12745	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_12750	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_12755	COG1846	Transcriptional regulator
FY149_12760	COG1764	response to oxidative stress
FY149_12775	COG0488	(ABC) transporter
FY149_12810	COG4221	oxidoreductase activity
FY149_12825	COG0433	COG0433 Predicted ATPase
FY149_12835	COG1733	regulation of RNA biosynthetic process
FY149_12840	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY149_12855	COG0656	L-ascorbic acid biosynthetic process
FY149_12860	COG3781	membrane
FY149_12865	COG2378	regulation of single-species biofilm formation
FY149_12875	COG4106	trans-aconitate 2-methyltransferase activity
FY149_12880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY149_12885	COG0840	transmembrane signaling receptor activity
FY149_12890	COG0583	DNA-binding transcription factor activity
FY149_12905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY149_12925	COG3909	cytochrome
FY149_12930	COG2010	Cytochrome c
FY149_12965	COG0789	Transcriptional regulator
FY149_12990	COG0517	IMP dehydrogenase activity
FY149_12990	COG4175	Glycine betaine
FY149_12995	COG4176	ABC-type proline glycine betaine transport system permease component
FY149_13015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_13025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY149_13025	COG2169	Transcriptional regulator
FY149_13035	COG2514	catechol 2,3-dioxygenase activity
FY149_13055	COG1272	protein, Hemolysin III
FY149_13065	COG1280	lysine exporter protein (LysE YggA)
FY149_13070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY149_13075	COG2111	Na H antiporter
FY149_13075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY149_13080	COG2111	Na H antiporter
FY149_13085	COG1006	Multisubunit Na H antiporter MnhC subunit
FY149_13090	COG0651	ATP synthesis coupled electron transport
FY149_13095	COG1863	multisubunit Na H antiporter MnhE subunit
FY149_13100	COG2212	antiporter activity
FY149_13105	COG1320	monovalent cation:proton antiporter activity
FY149_13110	COG4957	zinc ion binding
FY149_13125	COG2166	iron-sulfur cluster assembly
FY149_13135	COG2205	protein histidine kinase activity
FY149_13180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY149_13185	COG2983	Belongs to the UPF0260 family
FY149_13200	COG2217	Heavy metal translocating P-type atpase
FY149_13230	COG2814	Major facilitator Superfamily
FY149_13235	COG1621	beta-fructofuranosidase activity
FY149_13240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY149_13290	COG4695	Portal protein
FY149_13405	COG3436	PFAM IS66 Orf2 family protein
FY149_13410	COG4372	Transposase
FY149_13415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY149_13495	COG4235	cytochrome complex assembly
FY149_13500	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY149_13505	COG1138	Cytochrome C-type biogenesis protein
FY149_13510	COG3088	subunit of a heme lyase
FY149_13515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY149_13520	COG0745	RESPONSE REGULATOR receiver
FY149_13525	COG2205	protein histidine kinase activity
FY149_13530	COG3011	Protein conserved in bacteria
FY149_13535	COG3713	MltA-interacting MipA family protein
FY149_13540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY149_13545	COG2202	Pas domain
FY149_13545	COG2205	protein histidine kinase activity
FY149_13555	COG0308	aminopeptidase N
FY149_13560	COG0697	spore germination
FY149_13575	COG0443	Heat shock 70 kDa protein
FY149_13610	COG0604	alcohol dehydrogenase
FY149_13615	COG1733	regulation of RNA biosynthetic process
FY149_13620	COG1968	undecaprenyl-diphosphatase activity
FY149_13625	COG2239	Acts as a magnesium transporter
FY149_13630	COG2814	Major facilitator Superfamily
FY149_13655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY149_13680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY149_13720	COG0741	lytic transglycosylase activity
FY149_13725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_13730	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY149_13735	COG0840	transmembrane signaling receptor activity
FY149_13745	COG1758	RNA polymerase activity
FY149_13765	COG0736	holo-[acyl-carrier-protein] synthase activity
FY149_13770	COG0681	Belongs to the peptidase S26 family
FY149_13775	COG0571	ribonuclease III activity
FY149_13780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY149_13790	COG0784	Response regulator, receiver
FY149_13795	COG1381	Involved in DNA repair and RecF pathway recombination
FY149_13805	COG2226	methyltransferase
FY149_13815	COG1418	mRNA catabolic process
FY149_13825	COG0346	lactoylglutathione lyase activity
FY149_13840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_13845	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY149_13850	COG0668	transmembrane transport
FY149_13860	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY149_13890	COG1742	UPF0060 membrane protein
FY149_13905	COG1183	phosphatidylcholine synthase activity
FY149_13910	COG0688	phosphatidylethanolamine metabolic process
FY149_13915	COG5265	(ABC) transporter
FY149_13955	COG2852	Protein conserved in bacteria
FY149_13960	COG0215	cysteine-tRNA ligase activity
FY149_13965	COG4221	oxidoreductase activity
FY149_13970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY149_13975	COG1286	toxin biosynthetic process
FY149_13990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY149_14000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY149_14010	COG0305	Participates in initiation and elongation during chromosome replication
FY149_14030	COG0359	binds to the 23S rRNA
FY149_14040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY149_14045	COG0360	Binds together with S18 to 16S ribosomal RNA
FY149_14055	COG0667	Aldo Keto reductase
FY149_14060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY149_14070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_14075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY149_14085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY149_14090	COG1561	YicC-like family, N-terminal region
FY149_14095	COG0194	GDP metabolic process
FY149_14110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY149_14115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY149_14125	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY149_14140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY149_14160	COG5001	Diguanylate cyclase
FY149_14160	COG4251	negative regulation of phosphorylation
FY149_14160	COG3706	GGDEF domain
FY149_14160	COG2203	Gaf domain
FY149_14165	COG3300	MHYT domain
FY149_14165	COG5001	Diguanylate cyclase
FY149_14170	COG4191	Histidine kinase
FY149_14175	COG4566	intracellular signal transduction
FY149_14185	COG0488	(ABC) transporter
FY149_14190	COG3706	GGDEF domain
FY149_14200	COG0105	UTP biosynthetic process
FY149_14220	COG0314	molybdopterin synthase activity
FY149_14230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY149_14235	COG0322	excinuclease ABC activity
FY149_14240	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_14265	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY149_14270	COG0243	molybdopterin cofactor binding
FY149_14285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY149_14290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY149_14295	COG2226	methyltransferase
FY149_14300	COG0628	permease
FY149_14310	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY149_14315	COG0248	Ppx GppA phosphatase
FY149_14340	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY149_14350	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY149_14355	COG0477	Major facilitator Superfamily
FY149_14360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY149_14370	COG0840	transmembrane signaling receptor activity
FY149_14375	COG0659	secondary active sulfate transmembrane transporter activity
FY149_14385	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY149_14390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY149_14400	COG0113	porphobilinogen synthase activity
FY149_14420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY149_14425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY149_14430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY149_14430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY149_14440	COG1280	lysine exporter protein (LysE YggA)
FY149_14445	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY149_14450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY149_14455	COG2814	Major facilitator Superfamily
FY149_14460	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY149_14480	COG0416	fatty acid biosynthetic process
FY149_14485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY149_14490	COG0776	regulation of translation
FY149_14525	COG0601	transmembrane transport
FY149_14530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_14535	COG0444	Belongs to the ABC transporter superfamily
FY149_14545	COG0747	negative chemotaxis
FY149_14555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY149_14560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY149_14575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY149_14580	COG0583	DNA-binding transcription factor activity
FY149_14585	COG0737	Belongs to the 5'-nucleotidase family
FY149_14605	COG2897	thiosulfate sulfurtransferase activity
FY149_14620	COG0415	Belongs to the DNA photolyase family
FY149_14630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY149_14660	COG3932	Exopolysaccharide synthesis, ExoD
FY149_14665	COG1238	metal cluster binding
FY149_14740	COG1612	heme a metabolic process
FY149_14750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY149_14755	COG0010	Belongs to the arginase family
FY149_14760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY149_14765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY149_14775	COG1832	CoA-binding protein
FY149_14805	COG2124	cytochrome p450
FY149_14810	COG2199	diguanylate cyclase activity
FY149_14815	COG0740	serine-type endopeptidase activity
FY149_14820	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY149_14825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY149_14835	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY149_14860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_14865	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_14870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_14880	COG0649	NAD binding
FY149_14890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY149_14895	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY149_14905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY149_14910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY149_14920	COG0713	ATP synthesis coupled electron transport
FY149_14935	COG1007	ATP synthesis coupled electron transport
FY149_14940	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY149_14940	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY149_14955	COG0442	prolyl-tRNA aminoacylation
FY149_14965	COG1136	(ABC) transporter
FY149_14980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY149_15000	COG0784	Response regulator, receiver
FY149_15010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY149_15015	COG0477	Major facilitator Superfamily
FY149_15030	COG0557	exoribonuclease II activity
FY149_15035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY149_15045	COG0758	DNA mediated transformation
FY149_15050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY149_15060	COG0540	Belongs to the ATCase OTCase family
FY149_15075	COG1960	acyl-CoA dehydrogenase activity
FY149_15080	COG0456	acetyltransferase
FY149_15100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY149_15105	COG2824	Alkylphosphonate utilization operon protein PhnA
FY149_15110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY149_15115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY149_15120	COG0154	amidase activity
FY149_15125	COG0456	acetyltransferase
FY149_15130	COG3811	Belongs to the UPF0386 family
FY149_15145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY149_15175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY149_15180	COG0439	Biotin carboxylase
FY149_15185	COG0511	ligase activity, forming carbon-carbon bonds
FY149_15190	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY149_15200	COG0436	Aminotransferase
FY149_15220	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_15225	COG1530	ribonuclease E activity
FY149_15235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY149_15255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY149_15260	COG0384	phenazine biosynthesis protein PhzF
FY149_15280	COG0633	Ferredoxin
FY149_15295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY149_15300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY149_15310	COG3768	UPF0283 membrane protein
FY149_15315	COG3106	COG3106 Predicted ATPase
FY149_15345	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY149_15380	COG0537	adenosine 5'-monophosphoramidase activity
FY149_15405	COG0052	Belongs to the universal ribosomal protein uS2 family
FY149_15410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY149_15415	COG0528	UMP kinase activity
FY149_15420	COG0233	cytoplasmic translational termination
FY149_15425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY149_15435	COG0750	zinc metalloprotease
FY149_15440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY149_15445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY149_15450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY149_15455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY149_15460	COG3494	Protein of unknown function (DUF1009)
FY149_15465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY149_15470	COG2186	Transcriptional regulator
FY149_15480	COG0765	amino acid transport
FY149_15485	COG0765	amino acid transport
FY149_15495	COG0372	Belongs to the citrate synthase family
FY149_15510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY149_15535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY149_15540	COG1459	type II secretion system
FY149_15595	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY149_15600	COG0148	phosphopyruvate hydratase activity
FY149_15610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY149_15615	COG0022	dehydrogenase e1 component
FY149_15615	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY149_15620	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY149_15630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY149_15640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY149_15645	COG0697	spore germination
FY149_15660	COG2867	negative regulation of translational initiation
FY149_15665	COG1546	Belongs to the CinA family
FY149_15670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY149_15670	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY149_15680	COG3852	Histidine kinase
FY149_15685	COG2204	response regulator
FY149_15690	COG5000	phosphorelay sensor kinase activity
FY149_15695	COG2204	response regulator
FY149_15700	COG0569	domain protein
FY149_15705	COG1923	regulation of RNA biosynthetic process
FY149_15710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY149_15715	COG3956	TIGRFAM MazG family protein
FY149_15725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY149_15725	COG1648	precorrin-2 dehydrogenase activity
FY149_15765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY149_15765	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY149_15770	COG0509	glycine decarboxylation via glycine cleavage system
FY149_15775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_15800	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY149_15805	COG0564	pseudouridine synthase activity
FY149_15825	COG0251	oxidation-reduction process
FY149_15830	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY149_15840	COG1671	Belongs to the UPF0178 family
FY149_15855	COG0450	alkyl hydroperoxide reductase
FY149_15860	COG0625	glutathione transferase activity
FY149_15870	COG2801	Transposase and inactivated derivatives
FY149_15875	COG0431	NADPH-dependent FMN reductase
FY149_15885	COG0798	PFAM Bile acid sodium symporter
FY149_15890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY149_15905	COG0321	lipoyl(octanoyl) transferase activity
FY149_15905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY149_15910	COG0084	hydrolase, TatD family'
FY149_15915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY149_15925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY149_15975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY149_15980	COG2095	MarC family integral membrane protein
FY149_15985	COG0517	IMP dehydrogenase activity
FY149_15985	COG0617	tRNA 3'-terminal CCA addition
FY149_15985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY149_15995	COG0629	single-stranded DNA binding
FY149_16000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY149_16010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY149_16030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY149_16035	COG1121	(ABC) transporter
FY149_16055	COG0667	Aldo Keto reductase
FY149_16065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY149_16150	COG2239	Acts as a magnesium transporter
FY149_16155	COG0243	molybdopterin cofactor binding
FY149_16165	COG0242	peptide deformylase activity
FY149_16175	COG2205	protein histidine kinase activity
FY149_16175	COG2202	Pas domain
FY149_16185	COG0321	lipoyl(octanoyl) transferase activity
FY149_16190	COG1064	alcohol dehydrogenase
FY149_16220	COG1862	Preprotein translocase
FY149_16240	COG2124	cytochrome p450
FY149_16255	COG0596	Alpha beta hydrolase
FY149_16265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_16270	COG0626	cystathionine gamma-synthase activity
FY149_16275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_16280	COG4597	amino acid ABC transporter
FY149_16285	COG0765	amino acid transport
FY149_16290	COG1126	abc transporter atp-binding protein
FY149_16305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY149_16320	COG0436	Aminotransferase
FY149_16350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY149_16360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY149_16365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_16370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY149_16385	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY149_16390	COG1489	DNA binding
FY149_16395	COG0024	Methionine aminopeptidase
FY149_16400	COG2003	Belongs to the UPF0758 family
FY149_16415	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY149_16440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY149_16445	COG0546	phosphoglycolate phosphatase activity
FY149_16455	COG0114	fumarate hydratase activity
FY149_16465	COG0504	CTP synthase activity
FY149_16475	COG0149	triose-phosphate isomerase activity
FY149_16485	COG0187	DNA topoisomerase II activity
FY149_16495	COG0740	serine-type endopeptidase activity
FY149_16505	COG0640	Transcriptional regulator
FY149_16510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY149_16515	COG0745	RESPONSE REGULATOR receiver
FY149_16530	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY149_16530	COG3264	Mechanosensitive ion channel
FY149_16595	COG1127	ABC transporter
FY149_16600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY149_16605	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_16615	COG0281	malic enzyme
FY149_16615	COG0280	phosphate acetyltransferase
FY149_16625	COG0778	Nitroreductase
FY149_16630	COG0823	Involved in the tonB-independent uptake of proteins
FY149_16645	COG1368	sulfuric ester hydrolase activity
FY149_16670	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY149_16690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY149_16710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY149_16725	COG0318	PFAM AMP-dependent synthetase and ligase
FY149_16735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY149_16735	COG0512	Glutamine amidotransferase of anthranilate synthase
FY149_16740	COG0343	queuine tRNA-ribosyltransferase activity
FY149_16745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY149_16760	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY149_16775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY149_16780	COG0134	indole-3-glycerol-phosphate synthase activity
FY149_16785	COG0315	cyclic pyranopterin monophosphate synthase activity
FY149_16790	COG0303	'Molybdopterin
FY149_16795	COG3706	GGDEF domain
FY149_16805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY149_16805	COG0475	glutathione-regulated potassium exporter activity
FY149_16815	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY149_16825	COG2814	Major facilitator Superfamily
FY149_16830	COG0746	molybdenum cofactor guanylyltransferase activity
FY149_16835	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY149_16840	COG0739	heme binding
FY149_16845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY149_16850	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY149_16855	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY149_16860	COG0805	protein transport
FY149_16865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY149_16870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY149_16875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY149_16880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY149_16885	COG1472	Belongs to the glycosyl hydrolase 3 family
FY149_16895	COG0018	arginyl-trna synthetase
FY149_16900	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY149_16925	COG0525	valine-tRNA ligase activity
FY149_16935	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY149_17075	COG1525	nuclease
FY149_17150	COG3567	Phage-associated protein, HI1409 family
FY149_17205	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY149_17390	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY149_17395	COG1058	Belongs to the CinA family
FY149_17395	COG1546	Belongs to the CinA family
FY149_17400	COG0589	response to stress
FY149_17405	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY149_17415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY149_17425	COG0640	Transcriptional regulator
FY149_17430	COG1914	H( )-stimulated, divalent metal cation uptake system
FY149_17440	COG1132	(ABC) transporter
FY149_17445	COG0628	permease
FY149_17480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY149_17490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY149_17500	COG0302	gtp cyclohydrolase
FY149_17505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY149_17510	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY149_17520	COG0516	GMP reductase activity
FY149_17520	COG0517	IMP dehydrogenase activity
FY149_17555	COG1760	l-serine dehydratase
FY149_17595	COG0583	DNA-binding transcription factor activity
FY149_17610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY149_17610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY149_17620	COG0347	Belongs to the P(II) protein family
FY149_17625	COG0174	glutamine synthetase
FY149_17655	COG0697	spore germination
FY149_17665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY149_17675	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY149_17705	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY149_17715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY149_17720	COG2186	Transcriptional regulator
FY149_17730	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY149_17735	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY149_17740	COG3845	ABC transporter
FY149_17745	COG1183	phosphatidylcholine synthase activity
FY149_17750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_17755	COG0679	Auxin Efflux Carrier
FY149_17760	COG0785	Cytochrome C biogenesis protein
FY149_17780	COG1278	Cold shock
FY149_17830	COG0577	efflux transmembrane transporter activity
FY149_17830	COG1136	(ABC) transporter
FY149_17835	COG0577	efflux transmembrane transporter activity
FY149_17835	COG1136	(ABC) transporter
FY149_17860	COG2151	metal-sulfur cluster biosynthetic enzyme
FY149_17865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY149_17870	COG0719	Fe-S assembly protein
FY149_17875	COG0396	ATPase activity
FY149_17880	COG0719	Fe-S assembly protein
FY149_17885	COG1104	cysteine desulfurase activity
FY149_17890	COG2945	thiolester hydrolase activity
FY149_17895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY149_17900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY149_17910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY149_17915	COG2833	Protein of unknown function (DUF455)
FY149_17920	COG0739	heme binding
FY149_17925	COG0513	Belongs to the DEAD box helicase family
FY149_17950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY149_17960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY149_17965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY149_17970	COG0047	phosphoribosylformylglycinamidine synthase activity
FY149_17985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_17990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY149_18010	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY149_18015	COG2814	Major facilitator Superfamily
FY149_18020	COG0483	inositol monophosphate 1-phosphatase activity
FY149_18025	COG0483	inositol monophosphate 1-phosphatase activity
FY149_18030	COG0037	tRNA processing
FY149_18035	COG2066	Belongs to the glutaminase family
FY149_18040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY149_18045	COG0861	Integral membrane protein TerC family
FY149_18060	COG1280	lysine exporter protein (LysE YggA)
FY149_18070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY149_18075	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY149_18085	COG0538	isocitrate dehydrogenase activity
FY149_18095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY149_18100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY149_18105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_18110	COG2313	pseudouridylate synthase activity
FY149_18120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_18125	COG4215	(ABC) transporter
FY149_18135	COG5425	PFAM Usg family protein
FY149_18145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY149_18150	COG1522	sequence-specific DNA binding
FY149_18155	COG1573	uracil-dna glycosylase
FY149_18165	COG2205	protein histidine kinase activity
FY149_18165	COG2202	Pas domain
FY149_18170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY149_18175	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY149_18180	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY149_18195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY149_18200	COG0842	Transport permease protein
FY149_18205	COG1131	(ABC) transporter
FY149_18210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY149_18210	COG0730	response to heat
FY149_18230	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY149_18235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY149_18255	COG0129	dihydroxy-acid dehydratase activity
FY149_18260	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY149_18265	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY149_18275	COG3739	integral membrane protein
FY149_18280	COG0203	ribosomal protein L17
FY149_18285	COG0202	RNA polymerase activity
FY149_18290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY149_18295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY149_18300	COG0563	adenylate kinase activity
FY149_18305	COG0201	protein transport
FY149_18310	COG0200	Binds to the 23S rRNA
FY149_18315	COG1841	ribosomal large subunit assembly
FY149_18320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY149_18325	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY149_18330	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY149_18335	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY149_18340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY149_18345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY149_18350	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY149_18355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY149_18360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY149_18365	COG0255	Belongs to the universal ribosomal protein uL29 family
FY149_18370	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY149_18375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY149_18380	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY149_18385	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY149_18390	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY149_18395	COG0089	rRNA binding
FY149_18400	COG0088	Forms part of the polypeptide exit tunnel
FY149_18405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY149_18410	COG0051	transcription antitermination factor activity, RNA binding
FY149_18415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY149_18420	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY149_18425	COG0049	tRNA binding
FY149_18430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY149_18450	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY149_18455	COG0085	RNA polymerase activity
FY149_18460	COG0222	ribosome binding
FY149_18465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY149_18470	COG0081	regulation of translation
FY149_18475	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY149_18485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY149_18495	COG1086	Polysaccharide biosynthesis protein
FY149_18500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY149_18505	COG0861	Integral membrane protein TerC family
FY149_18510	COG3895	Periplasmic Protein
FY149_18530	COG1132	(ABC) transporter
FY149_18535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY149_18555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY149_18590	COG2205	protein histidine kinase activity
FY149_18590	COG2198	Histidine kinase
FY149_18590	COG0784	Response regulator, receiver
FY149_18590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_18595	COG0784	Response regulator, receiver
FY149_18600	COG2202	Pas domain
FY149_18600	COG3920	Histidine kinase
FY149_18605	COG0784	Response regulator, receiver
FY149_18610	COG4251	negative regulation of phosphorylation
FY149_18625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY149_18630	COG1607	acyl-coa hydrolase
FY149_18650	COG2910	NAD(P)H-binding
FY149_18655	COG1733	regulation of RNA biosynthetic process
FY149_18670	COG0556	nucleotide-excision repair
FY149_18680	COG2382	esterase
FY149_18700	COG0484	heat shock protein binding
FY149_19010	COG3706	GGDEF domain
FY149_19030	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_19035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_19050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY149_19060	COG2207	Transcriptional regulator
FY149_19065	COG1064	alcohol dehydrogenase
FY149_19070	COG1252	NADH dehydrogenase
FY149_19075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY149_19080	COG2197	response regulator
FY149_19085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY149_19120	COG0656	L-ascorbic acid biosynthetic process
FY149_19135	COG0440	acetolactate synthase activity
FY149_19140	COG0028	Belongs to the TPP enzyme family
FY149_19150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY149_19155	COG3830	Belongs to the UPF0237 family
FY149_19155	COG0560	Phosphoserine phosphatase
FY149_19175	COG0330	HflC and HflK could
FY149_19180	COG0330	HflC and HflK could
FY149_19190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY149_19225	COG0277	FAD linked oxidase domain protein
FY149_19230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_19270	COG1335	isochorismatase
FY149_19295	COG2264	protein methyltransferase activity
FY149_19300	COG1999	signal sequence binding
FY149_19310	COG0835	chemotaxis
FY149_19320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY149_19325	COG0583	DNA-binding transcription factor activity
FY149_19335	COG1247	-acetyltransferase
FY149_19345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY149_19350	COG0497	DNA recombination
FY149_19355	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY149_19365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY149_19370	COG0849	cell division
FY149_19375	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY149_19380	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY149_19385	COG0477	Major facilitator Superfamily
FY149_19390	COG5001	Diguanylate cyclase
FY149_19395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY149_19400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY149_19405	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY149_19415	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY149_19420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY149_19430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY149_19445	COG0275	rRNA processing
FY149_19450	COG2001	Belongs to the MraZ family
FY149_19475	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY149_19505	COG4106	trans-aconitate 2-methyltransferase activity
FY149_19525	COG2226	methyltransferase
FY149_19535	COG2267	carboxylic ester hydrolase activity
FY149_19540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY149_19555	COG0251	oxidation-reduction process
FY149_19570	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_19575	COG2814	Major facilitator Superfamily
FY149_19605	COG1012	belongs to the aldehyde dehydrogenase family
FY149_19610	COG0174	glutamine synthetase
FY149_19615	COG0531	amino acid
FY149_19625	COG1737	Transcriptional regulator
FY149_19630	COG2182	Extracellular solute-binding protein
FY149_19645	COG3842	ATPase activity
FY149_19705	COG2968	Membrane
FY149_19715	COG0432	Pfam Uncharacterised protein family UPF0047
FY149_19730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY149_19735	COG0358	DNA primase activity
FY149_19755	COG0505	Belongs to the CarA family
FY149_19760	COG0534	Mate efflux family protein
FY149_19775	COG2321	neutral zinc metallopeptidase
FY149_19790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY149_19800	COG3706	GGDEF domain
FY149_19815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY149_19825	COG1522	sequence-specific DNA binding
FY149_19830	COG0492	ferredoxin-NADP+ reductase activity
FY149_19835	COG0583	DNA-binding transcription factor activity
FY149_19845	COG1902	pentaerythritol trinitrate reductase activity
FY149_19870	COG0387	Pfam Sodium calcium exchanger
FY149_19875	COG0436	Aminotransferase
FY149_19880	COG2199	diguanylate cyclase activity
FY149_19880	COG2200	EAL domain
FY149_19895	COG1278	Cold shock
FY149_19900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY149_19910	COG1846	Transcriptional regulator
FY149_19915	COG0745	RESPONSE REGULATOR receiver
FY149_19925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY149_19945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY149_19955	COG1496	oxidoreductase activity
FY149_19970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY149_19980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY149_19995	COG0840	transmembrane signaling receptor activity
FY149_20000	COG1012	belongs to the aldehyde dehydrogenase family
FY149_20005	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY149_20010	COG5001	Diguanylate cyclase
FY149_20010	COG3300	MHYT domain
FY149_20015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY149_20020	COG5001	Diguanylate cyclase
FY149_20030	COG0193	aminoacyl-tRNA hydrolase activity
FY149_20040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY149_20065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY149_20075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY149_20075	COG2857	Cytochrome c1
FY149_20095	COG1132	(ABC) transporter
FY149_20105	COG1132	(ABC) transporter
FY149_20115	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY149_20130	COG0408	coproporphyrinogen oxidase activity
FY149_20145	COG0617	tRNA 3'-terminal CCA addition
FY149_20160	COG0714	Associated with various cellular activities
FY149_20180	COG0454	-acetyltransferase
FY149_20195	COG0477	Major facilitator Superfamily
FY149_20205	COG0435	Glutathione S-transferase
FY149_20210	COG0494	nUDIX hydrolase
FY149_20220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY149_20225	COG3135	benzoate transporter
FY149_20250	COG0740	serine-type endopeptidase activity
FY149_20265	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY149_20270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY149_20295	COG4175	Glycine betaine
FY149_20315	COG1435	thymidine kinase activity
FY149_20340	COG1629	transport
FY149_20340	COG4771	TonB-dependent receptor
FY149_20350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY149_20350	COG0512	Glutamine amidotransferase of anthranilate synthase
FY149_20365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY149_20375	COG0366	Alpha amylase catalytic
FY149_20380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_20400	COG1160	GTP binding
FY149_20420	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY149_20430	COG0024	Methionine aminopeptidase
FY149_20440	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_20460	COG0583	DNA-binding transcription factor activity
FY149_20475	COG0402	S-adenosylhomocysteine deaminase activity
FY149_20485	COG1304	FMN binding
FY149_20495	COG1309	transcriptional regulator
FY149_20500	COG1686	Belongs to the peptidase S11 family
FY149_20510	COG2351	hydroxyisourate hydrolase activity
FY149_20515	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY149_20540	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY149_20550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_20550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY149_20560	COG0513	Belongs to the DEAD box helicase family
FY149_20570	COG2259	Doxx family
FY149_20575	COG1376	ErfK ybiS ycfS ynhG family protein
FY149_20585	COG2308	Evidence 4 Homologs of previously reported genes of
FY149_20595	COG1305	Transglutaminase-like
FY149_20620	COG4214	carbohydrate transport
FY149_20630	COG4213	ABC transporter substrate-binding protein
FY149_20685	COG2948	multi-organism process
FY149_20695	COG3701	Conjugal transfer protein
FY149_20700	COG3846	protein secretion by the type IV secretion system
FY149_20715	COG3451	type IV secretory pathway VirB4
FY149_20730	COG4962	Type ii secretion system protein e
FY149_20755	COG0583	DNA-binding transcription factor activity
FY149_20765	COG1566	PFAM secretion protein HlyD family protein
FY149_20780	COG2207	Transcriptional regulator
FY149_20785	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_20795	COG0583	DNA-binding transcription factor activity
FY149_20805	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY149_20820	COG0583	DNA-binding transcription factor activity
FY149_20830	COG0741	lytic transglycosylase activity
FY149_20855	COG1192	Involved in chromosome partitioning
FY149_20890	COG2814	Major facilitator Superfamily
FY149_20900	COG5489	Protein of unknown function (DUF736)
FY149_20920	COG3012	SEC-C Motif Domain Protein
FY149_20950	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY149_20980	COG1204	response to ionizing radiation
FY149_20995	COG0514	ATP-dependent DNA helicase (RecQ)
FY149_21045	COG0583	DNA-binding transcription factor activity
FY149_21050	COG1902	pentaerythritol trinitrate reductase activity
FY149_21055	COG0583	DNA-binding transcription factor activity
FY149_21070	COG1335	isochorismatase
FY149_21075	COG0583	DNA-binding transcription factor activity
FY149_21080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY149_21090	COG4584	PFAM Integrase catalytic
FY149_21105	COG0840	transmembrane signaling receptor activity
FY149_21120	COG1410	methionine synthase
FY149_21120	COG0646	methionine synthase
FY149_21135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_21165	COG1215	transferase activity, transferring glycosyl groups
FY149_21195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY149_21210	COG2346	COG2346, Truncated hemoglobins
FY149_21230	COG1309	transcriptional regulator
FY149_21245	COG0494	nUDIX hydrolase
FY149_21255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_21260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_21290	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY149_21295	COG0830	nickel cation binding
FY149_21300	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY149_21315	COG0804	urea catabolic process
FY149_21320	COG1442	glycosyl transferase family 8
FY149_21325	COG3755	Protein conserved in bacteria
FY149_21335	COG0832	Belongs to the urease beta subunit family
FY149_21340	COG3813	Protein conserved in bacteria
FY149_21345	COG0831	urea catabolic process
FY149_21350	COG0829	nickel cation binding
FY149_21380	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY149_21395	COG0174	glutamine synthetase
FY149_21400	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_21405	COG0784	Response regulator, receiver
FY149_21405	COG2198	Histidine kinase
FY149_21405	COG5002	protein histidine kinase activity
FY149_21420	COG0726	polysaccharide deacetylase
FY149_21455	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY149_21530	COG0564	pseudouridine synthase activity
FY149_21540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY149_21550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY149_21575	COG0346	lactoylglutathione lyase activity
FY149_21585	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY149_21595	COG2832	Protein of unknown function (DUF454)
FY149_21600	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY149_21605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_21610	COG4558	Periplasmic binding protein
FY149_21620	COG3721	Heme iron utilization protein
FY149_21635	COG3655	Transcriptional regulator
FY149_21660	COG2205	protein histidine kinase activity
FY149_21700	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_21705	COG4605	iron ion homeostasis
FY149_21710	COG4604	ABC transporter, ATP-binding protein
FY149_21715	COG0783	Belongs to the Dps family
FY149_21730	COG0840	transmembrane signaling receptor activity
FY149_21730	COG2972	Histidine kinase
FY149_21735	COG0656	L-ascorbic acid biosynthetic process
FY149_21740	COG2814	Major facilitator Superfamily
FY149_21750	COG0583	DNA-binding transcription factor activity
FY149_21755	COG0657	acetylesterase activity
FY149_21760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_21780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY149_21785	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY149_21790	COG0288	reversible hydration of carbon dioxide
FY149_21800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY149_21820	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY149_21825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY149_21830	COG0778	Nitroreductase
FY149_21835	COG2267	carboxylic ester hydrolase activity
FY149_21840	COG0251	oxidation-reduction process
FY149_21845	COG1335	isochorismatase
FY149_21850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_21860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY149_21875	COG1175	transmembrane transport
FY149_21880	COG0395	ABC-type sugar transport system, permease component
FY149_21885	COG3842	ATPase activity
FY149_21890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_21900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY149_21915	COG4608	Belongs to the ABC transporter superfamily
FY149_21920	COG0444	Belongs to the ABC transporter superfamily
FY149_21925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_21930	COG0601	transmembrane transport
FY149_21985	COG2159	amidohydrolase
FY149_21990	COG1960	acyl-CoA dehydrogenase activity
FY149_22020	COG0745	RESPONSE REGULATOR receiver
FY149_22030	COG1902	pentaerythritol trinitrate reductase activity
FY149_22030	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY149_22035	COG3842	ATPase activity
FY149_22045	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_22050	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_22055	COG0745	RESPONSE REGULATOR receiver
FY149_22065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY149_22070	COG0583	DNA-binding transcription factor activity
FY149_22075	COG1278	Cold shock
FY149_22110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY149_22115	COG1309	transcriptional regulator
FY149_22120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_22125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY149_22135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY149_22140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY149_22160	COG0583	DNA-binding transcription factor activity
FY149_22165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_22170	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY149_22175	COG4149	molybdate abc transporter
FY149_22180	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY149_22195	COG2022	thiamine diphosphate biosynthetic process
FY149_22210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY149_22220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY149_22230	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY149_22250	COG1132	(ABC) transporter
FY149_22255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY149_22300	COG4166	transmembrane transport
FY149_22305	COG0601	transmembrane transport
FY149_22310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_22325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY149_22330	COG3142	Participates in the control of copper homeostasis
FY149_22335	COG2814	Major facilitator Superfamily
FY149_22350	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_22355	COG1737	Transcriptional regulator
FY149_22365	COG3842	ATPase activity
FY149_22375	COG0395	ABC-type sugar transport system, permease component
FY149_22395	COG2188	Transcriptional regulator
FY149_22400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY149_22405	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY149_22410	COG1940	carbohydrate kinase activity
FY149_22420	COG0671	phosphoesterase, PA-phosphatase related
FY149_22425	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY149_22430	COG0156	8-amino-7-oxononanoate synthase activity
FY149_22440	COG0729	surface antigen
FY149_22450	COG0835	chemotaxis
FY149_22460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY149_22465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY149_22470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY149_22475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY149_22480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY149_22485	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY149_22500	COG4974	Belongs to the 'phage' integrase family
FY149_22525	COG1280	lysine exporter protein (LysE YggA)
FY149_22535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY149_22540	COG0567	Dehydrogenase, E1 component
FY149_22545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY149_22550	COG0045	succinate-CoA ligase (ADP-forming) activity
FY149_22555	COG0039	L-malate dehydrogenase activity
FY149_22560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY149_22610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY149_22615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY149_22620	COG0181	hydroxymethylbilane synthase activity
FY149_22660	COG1872	DUF167
FY149_22665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY149_22675	COG1217	gtp-binding protein TYPA
FY149_22680	COG0339	signal peptide processing
FY149_22685	COG1846	Transcriptional regulator
FY149_22695	COG0137	argininosuccinate synthase activity
FY149_22705	COG1280	lysine exporter protein (LysE YggA)
FY149_22710	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY149_22715	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY149_22725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY149_22740	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY149_22745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY149_22750	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY149_22760	COG4181	ATPase activity
FY149_22770	COG0670	Belongs to the BI1 family
FY149_22785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY149_22790	COG4133	protoheme IX ABC transporter activity
FY149_22795	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY149_22800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY149_22825	COG2917	probably involved in intracellular septation
FY149_22830	COG0552	protein localization to endoplasmic reticulum
FY149_22835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY149_22840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY149_22855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY149_22860	COG0287	Prephenate dehydrogenase
FY149_22860	COG1605	Chorismate mutase
FY149_22865	COG0228	four-way junction DNA binding
FY149_22870	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY149_22875	COG0336	Belongs to the RNA methyltransferase TrmD family
FY149_22885	COG0335	large ribosomal subunit rRNA binding
FY149_22890	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY149_22895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY149_22910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY149_22930	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY149_22950	COG0488	(ABC) transporter
FY149_22960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY149_22970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY149_22975	COG0142	geranyltranstransferase activity
FY149_22980	COG2885	chlorophyll binding
FY149_22985	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY149_22990	COG2223	nitrite transmembrane transporter activity
FY149_22995	COG1349	DNA-binding transcription factor activity
FY149_23000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY149_23005	COG2197	response regulator
FY149_23010	COG1132	(ABC) transporter
FY149_23020	COG3459	Glycosyltransferase 36 associated
FY149_23025	COG1473	amidohydrolase
FY149_23030	COG0579	oxidoreductase
FY149_23040	COG0129	dihydroxy-acid dehydratase activity
FY149_23045	COG2084	Dehydrogenase
FY149_23050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY149_23055	COG0277	FAD linked oxidase domain protein
FY149_23060	COG2186	Transcriptional regulator
FY149_23070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY149_23075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY149_23080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY149_23085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY149_23095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY149_23100	COG0495	leucyl-tRNA aminoacylation
FY149_23115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY149_23120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY149_23135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY149_23140	COG1946	Acyl-CoA thioesterase
FY149_23145	COG0347	Belongs to the P(II) protein family
FY149_23150	COG0004	ammonium transporteR
FY149_23155	COG1674	ftsk spoiiie
FY149_23160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY149_23175	COG0745	RESPONSE REGULATOR receiver
FY149_23185	COG1329	Transcriptional regulator
FY149_23195	COG2270	Major facilitator Superfamily
FY149_23210	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_23225	COG0494	nUDIX hydrolase
FY149_23230	COG2861	carbohydrate metabolic process
FY149_23235	COG0793	Belongs to the peptidase S41A family
FY149_23245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY149_23250	COG0799	negative regulation of ribosome biogenesis
FY149_23255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY149_23260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY149_23265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY149_23270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY149_23285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY149_23290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY149_23315	COG0066	3-isopropylmalate dehydratase activity
FY149_23320	COG0473	3-isopropylmalate dehydrogenase activity
FY149_23325	COG1858	cytochrome C peroxidase
FY149_23330	COG1797	cobyrinic acid a,c-diamide synthase activity
FY149_23340	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY149_23405	COG1492	cobalamin metabolic process
FY149_23420	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_23425	COG3254	rhamnose metabolic process
FY149_23430	COG0246	Mannitol dehydrogenase
FY149_23435	COG1063	alcohol dehydrogenase
FY149_23460	COG1129	ABC transporter
FY149_23465	COG2186	Transcriptional regulator
FY149_23470	COG2721	sulfolactate sulfo-lyase activity
FY149_23475	COG0138	bifunctional purine biosynthesis protein purh
FY149_23485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY149_23485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY149_23490	COG0501	Belongs to the peptidase M48B family
FY149_23510	COG0357	Ribosomal RNA small subunit methyltransferase G
FY149_23515	COG0445	tRNA wobble uridine modification
FY149_23520	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY149_23525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY149_23530	COG1981	membrane
FY149_23535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY149_23540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY149_23545	COG0424	maF-like protein
FY149_23550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY149_23555	COG0237	dephospho-CoA kinase activity
FY149_23565	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY149_23570	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY149_23580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY149_23605	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY149_23620	COG0135	phosphoribosylanthranilate isomerase activity
FY149_23625	COG0133	tryptophan synthase activity
FY149_23630	COG0159	tryptophan synthase activity
FY149_23635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY149_23650	COG1074	ATP-dependent DNA helicase activity
FY149_23660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY149_23665	COG0802	atpase or kinase
FY149_23670	COG2205	protein histidine kinase activity
FY149_23675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY149_23680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY149_23685	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY149_23685	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY149_23690	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY149_23695	COG0642	Histidine kinase
FY149_23700	COG0745	RESPONSE REGULATOR receiver
FY149_23705	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY149_23715	COG1652	LysM domain
FY149_23720	COG1072	(Pantothenic acid kinase))
FY149_23725	COG0140	phosphoribosyl-ATP diphosphatase activity
FY149_23730	COG0107	imidazoleglycerol-phosphate synthase activity
FY149_23735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY149_23740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY149_23750	COG0131	Imidazoleglycerol-phosphate dehydratase
FY149_23755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY149_23760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY149_23770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY149_23785	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY149_23795	COG1643	Atp-dependent helicase
FY149_23840	COG1940	carbohydrate kinase activity
FY149_23860	COG1072	(Pantothenic acid kinase))
FY149_23870	COG1780	Probably involved in ribonucleotide reductase function
FY149_23890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY149_23920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY149_23930	COG2813	Specifically methylates the guanine in position
FY149_23935	COG1185	polyribonucleotide nucleotidyltransferase activity
FY149_23940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY149_23945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY149_23950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY149_23955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY149_23955	COG3064	Membrane
FY149_23970	COG0779	Required for maturation of 30S ribosomal subunits
FY149_23975	COG2814	Major facilitator Superfamily
FY149_23985	COG2951	lytic endotransglycosylase activity
FY149_23990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY149_24000	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY149_24005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY149_24020	COG2816	NAD+ diphosphatase activity
FY149_24025	COG0077	Prephenate dehydratase
FY149_24025	COG1605	Chorismate mutase
FY149_24030	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY149_24035	COG3474	cytochrome
FY149_24045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY149_24050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY149_24055	COG1278	Cold shock
FY149_24060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_24070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY149_24070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY149_24075	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY149_24105	COG2900	Belongs to the SlyX family
FY149_24115	COG0484	heat shock protein binding
FY149_24120	COG0443	Heat shock 70 kDa protein
FY149_24135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY149_24140	COG1744	ABC transporter substrate-binding protein PnrA-like
FY149_24145	COG3845	ABC transporter
FY149_24150	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY149_24155	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY149_24160	COG0295	cytidine deaminase activity
FY149_24165	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY149_24170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY149_24175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY149_24185	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY149_24190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY149_24195	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY149_24205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY149_24210	COG1845	cytochrome c oxidase, subunit III
FY149_24215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY149_24220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY149_24225	COG0477	Major facilitator Superfamily
FY149_24230	COG0070	glutamate synthase
FY149_24230	COG0069	glutamate synthase activity
FY149_24230	COG0067	glutamate synthase
FY149_24235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY149_24250	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY149_24260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY149_24290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY149_24310	COG0848	biopolymer transport protein
FY149_24320	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY149_24335	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY149_24340	COG3454	Phosphonate metabolism
FY149_24345	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY149_24350	COG3639	organic phosphonate transmembrane transporter activity
FY149_24355	COG3639	organic phosphonate transmembrane transporter activity
FY149_24365	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY149_24375	COG4778	phosphonate C-P lyase system protein PhnL
FY149_24380	COG4107	phosphonate C-P lyase system protein PhnK
FY149_24385	COG3627	carbon phosphorus lyase activity
FY149_24390	COG3626	phosphonate metabolism
FY149_24395	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY149_24400	COG3624	Phosphonate C-P lyase system protein PhnG
FY149_24405	COG2188	Transcriptional regulator
FY149_24410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY149_24415	COG0837	glucose binding
FY149_24420	COG1803	Methylglyoxal synthase
FY149_24425	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY149_24430	COG4166	transmembrane transport
FY149_24435	COG4174	ABC transporter (Permease)
FY149_24440	COG4239	(ABC) transporter, permease
FY149_24445	COG4172	Belongs to the ABC transporter superfamily
FY149_24450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_24455	COG0174	glutamine synthetase
FY149_24460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY149_24465	COG3265	gluconokinase activity
FY149_24470	COG1174	glycine betaine transport
FY149_24475	COG1125	glycine betaine transport
FY149_24480	COG1174	glycine betaine transport
FY149_24485	COG1732	Glycine betaine
FY149_24495	COG1959	2 iron, 2 sulfur cluster binding
FY149_24500	COG1840	ABC-type Fe3 transport system, periplasmic component
FY149_24510	COG4269	membrane
FY149_24525	COG0697	spore germination
FY149_24540	COG0791	NLP P60 protein
FY149_24550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY149_24555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY149_24590	COG4964	Belongs to the GSP D family
FY149_24635	COG3422	double-strand break repair
FY149_24640	COG3757	hydrolase, family 25
FY149_24645	COG0697	spore germination
FY149_24650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY149_24665	COG0492	ferredoxin-NADP+ reductase activity
FY149_24680	COG0481	GTPase activity
FY149_24685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY149_24700	COG1396	sequence-specific DNA binding
FY149_24715	COG2169	Transcriptional regulator
FY149_24715	COG1917	Cupin 2, conserved barrel domain protein
FY149_24720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY149_24745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY149_24750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY149_24755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY149_24765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY149_24770	COG0072	phenylalanine-tRNA ligase activity
FY149_24770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY149_24775	COG0667	Aldo Keto reductase
FY149_24795	COG4977	sequence-specific DNA binding
FY149_24820	COG1570	exodeoxyribonuclease VII activity
FY149_24825	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_24835	COG1846	Transcriptional regulator
FY149_24845	COG2309	aminopeptidase activity
FY149_24855	COG1393	Belongs to the ArsC family
FY149_24870	COG1309	transcriptional regulator
FY149_24880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY149_24880	COG0519	Catalyzes the synthesis of GMP from XMP
FY149_24895	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY149_24925	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY149_24935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY149_24945	COG1968	undecaprenyl-diphosphatase activity
FY149_24960	COG0284	orotidine-5'-phosphate decarboxylase activity
FY149_24970	COG3963	phosphatidate phosphatase activity
FY149_24980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY149_24985	COG0792	nuclease activity
FY149_25000	COG1175	transmembrane transport
FY149_25005	COG0395	ABC-type sugar transport system, permease component
FY149_25010	COG3842	ATPase activity
FY149_25020	COG0189	ligase activity
FY149_25030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY149_25035	COG1280	lysine exporter protein (LysE YggA)
FY149_25040	COG0756	dUTP diphosphatase activity
FY149_25045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY149_25050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY149_25065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY149_25070	COG2226	methyltransferase
FY149_25075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY149_25080	COG1024	Enoyl-CoA hydratase
FY149_25085	COG0268	Binds directly to 16S ribosomal RNA
FY149_25090	COG1192	Involved in chromosome partitioning
FY149_25095	COG1475	DNA binding
FY149_25100	COG0640	Transcriptional regulator
FY149_25115	COG1126	abc transporter atp-binding protein
FY149_25120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY149_25125	COG1609	Transcriptional regulator
FY149_25160	COG3239	Fatty acid desaturase
FY149_25170	COG1278	Cold shock
FY149_25245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY149_25245	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY149_25280	COG4191	Histidine kinase
FY149_25285	COG1132	(ABC) transporter
FY149_25295	COG0640	Transcriptional regulator
FY149_25325	COG4977	sequence-specific DNA binding
FY149_25330	COG2211	Major facilitator Superfamily
FY149_25335	COG2807	transmembrane transport
FY149_25340	COG1846	Transcriptional regulator
FY149_25355	COG2814	Major facilitator Superfamily
FY149_25385	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY149_25400	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY149_25405	COG0583	DNA-binding transcription factor activity
FY149_25420	COG0071	Belongs to the small heat shock protein (HSP20) family
FY149_25465	COG3838	Conjugal transfer protein Trbc
FY149_25470	COG3702	type iv secretory pathway
FY149_25475	COG3451	type IV secretory pathway VirB4
FY149_25490	COG3704	protein secretion by the type IV secretion system
FY149_25500	COG3736	Type IV secretory pathway, component VirB8
FY149_25505	COG3504	Conjugal transfer protein
FY149_25510	COG2948	multi-organism process
FY149_25515	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY149_25615	COG3831	ATPase activity
FY149_25630	COG3505	Type IV secretory pathway VirD4
FY149_25655	COG0583	DNA-binding transcription factor activity
FY149_25695	COG0745	RESPONSE REGULATOR receiver
FY149_25735	COG3842	ATPase activity
FY149_25740	COG4208	sulfate ABC transporter
FY149_25745	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY149_25765	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY149_25770	COG1942	4-Oxalocrotonate Tautomerase
FY149_25780	COG3971	2-oxopent-4-enoate hydratase activity
FY149_25790	COG1414	Transcriptional regulator
FY149_25800	COG1137	ATPase activity
FY149_25815	COG4177	L-phenylalanine transmembrane transporter activity
FY149_25835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY149_25840	COG1175	transmembrane transport
FY149_25845	COG0395	ABC-type sugar transport system, permease component
FY149_25855	COG0366	Alpha amylase catalytic
FY149_25860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY149_25865	COG1082	Xylose isomerase domain protein TIM barrel
FY149_25870	COG3842	ATPase activity
FY149_25880	COG1940	carbohydrate kinase activity
FY149_25885	COG0395	ABC-type sugar transport system, permease component
FY149_25895	COG2182	Extracellular solute-binding protein
FY149_25900	COG0673	inositol 2-dehydrogenase activity
FY149_25930	COG1126	abc transporter atp-binding protein
FY149_25935	COG0765	amino acid transport
FY149_25940	COG0765	amino acid transport
FY149_25950	COG4608	Belongs to the ABC transporter superfamily
FY149_25960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_25975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_25980	COG0583	DNA-binding transcription factor activity
FY149_25985	COG2423	ornithine cyclodeaminase activity
FY149_25995	COG1957	nucleoside hydrolase
FY149_26015	COG1335	isochorismatase
FY149_26020	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_26065	COG0583	DNA-binding transcription factor activity
FY149_26070	COG1902	pentaerythritol trinitrate reductase activity
FY149_26075	COG0583	DNA-binding transcription factor activity
FY149_26080	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_26090	COG1335	isochorismatase
FY149_26095	COG0583	DNA-binding transcription factor activity
FY149_26105	COG1695	Transcriptional regulator
FY149_26185	COG2207	Transcriptional regulator
FY149_26230	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_26245	COG1802	Transcriptional regulator
FY149_26250	COG3485	protocatechuate 3,4-dioxygenase
FY149_26255	COG3971	2-oxopent-4-enoate hydratase activity
FY149_26270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY149_26275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY149_26290	COG1063	alcohol dehydrogenase
FY149_26300	COG1960	acyl-CoA dehydrogenase activity
FY149_26305	COG1024	Enoyl-CoA hydratase
FY149_26315	COG1012	belongs to the aldehyde dehydrogenase family
FY149_26320	COG0477	Major facilitator Superfamily
FY149_26335	COG3706	GGDEF domain
FY149_26355	COG1846	Transcriptional regulator
FY149_26395	COG1012	belongs to the aldehyde dehydrogenase family
FY149_26405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY149_26415	COG3386	PFAM SMP-30 Gluconolaconase
FY149_26420	COG3622	Belongs to the hyi family
FY149_26425	COG2084	Dehydrogenase
FY149_26450	COG1940	carbohydrate kinase activity
FY149_26455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY149_26465	COG1129	ABC transporter
FY149_26485	COG0583	DNA-binding transcription factor activity
FY149_26490	COG2271	Major facilitator Superfamily
FY149_26500	COG2272	Belongs to the type-B carboxylesterase lipase family
FY149_26520	COG1129	ABC transporter
FY149_26545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY149_26555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY149_26590	COG0583	DNA-binding transcription factor activity
FY149_26595	COG1414	Transcriptional regulator
FY149_26605	COG4948	Mandelate Racemase Muconate Lactonizing
FY149_26615	COG3842	ATPase activity
FY149_26620	COG1175	transmembrane transport
FY149_26625	COG0395	ABC-type sugar transport system, permease component
FY149_26635	COG0477	Major facilitator Superfamily
FY149_26670	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY149_26690	COG0747	negative chemotaxis
FY149_26700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_26715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY149_26725	COG4215	(ABC) transporter
FY149_26780	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY149_26785	COG0251	oxidation-reduction process
FY149_26790	COG3547	Transposase (IS116 IS110 IS902 family)
FY149_26825	COG1028	Short-chain dehydrogenase reductase Sdr
FY149_26830	COG1335	isochorismatase
FY149_26840	COG1309	transcriptional regulator
FY149_26845	COG4604	ABC transporter, ATP-binding protein
FY149_26850	COG4605	iron ion homeostasis
FY149_26855	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY149_26865	COG2132	Multicopper oxidase
FY149_26870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY149_26875	COG4771	TonB-dependent receptor
FY149_26910	COG1695	Transcriptional regulator
FY149_26945	COG2132	Multicopper oxidase
FY149_26980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY149_27000	COG1192	Involved in chromosome partitioning
FY149_27005	COG1475	DNA binding
FY149_27010	COG0640	Transcriptional regulator
FY149_27015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY149_27045	COG2211	Major facilitator Superfamily
FY149_27090	COG4974	Belongs to the 'phage' integrase family
FY149_27095	COG1051	belongs to the nudix hydrolase family
FY149_27160	COG3012	SEC-C Motif Domain Protein
FY149_27195	COG2824	Alkylphosphonate utilization operon protein PhnA
FY149_27220	COG1280	lysine exporter protein (LysE YggA)
FY149_27285	COG5489	Protein of unknown function (DUF736)
FY149_27370	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY149_27385	COG0747	negative chemotaxis
FY149_27405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_27410	COG0584	glycerophosphoryl diester phosphodiesterase
FY149_27415	COG0483	inositol monophosphate 1-phosphatase activity
FY149_27480	COG3161	chorismate lyase activity
FY149_27630	COG3436	PFAM IS66 Orf2 family protein
FY149_27725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY149_27755	COG0583	DNA-binding transcription factor activity
FY149_27760	COG0747	negative chemotaxis
FY149_27775	COG0252	asparaginase activity
FY149_27780	COG0583	DNA-binding transcription factor activity
FY149_27800	COG3842	ATPase activity
FY149_27825	COG3701	Conjugal transfer protein
FY149_27830	COG3846	protein secretion by the type IV secretion system
FY149_27840	COG5314	conjugation
FY149_27845	COG3451	type IV secretory pathway VirB4
FY149_27860	COG4962	Type ii secretion system protein e
FY149_27870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY149_27905	COG1192	Involved in chromosome partitioning
FY149_27915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs