locus-tag	class	description
FY150_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY150_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY150_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY150_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY150_00025	COG1420	regulation of RNA biosynthetic process
FY150_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY150_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY150_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY150_00050	COG1137	ATPase activity
FY150_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY150_00065	COG0616	signal peptide processing
FY150_00070	COG0776	regulation of translation
FY150_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY150_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY150_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY150_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY150_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY150_00115	COG0728	peptidoglycan biosynthetic process
FY150_00125	COG0180	Tryptophanyl-tRNA synthetase
FY150_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY150_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY150_00145	COG0456	acetyltransferase
FY150_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY150_00165	COG1702	phosphate starvation-inducible protein PhoH
FY150_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY150_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY150_00185	COG1396	sequence-specific DNA binding
FY150_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY150_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY150_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_00210	COG0242	peptide deformylase activity
FY150_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY150_00220	COG0101	tRNA pseudouridine synthase activity
FY150_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY150_00235	COG2171	N-acyltransferase activity
FY150_00245	COG0840	transmembrane signaling receptor activity
FY150_00250	COG1957	nucleoside hydrolase
FY150_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY150_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY150_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY150_00295	COG0706	membrane insertase activity
FY150_00300	COG0594	ribonuclease P activity
FY150_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY150_00310	COG0840	transmembrane signaling receptor activity
FY150_00330	COG2226	methyltransferase
FY150_00335	COG3842	ATPase activity
FY150_00340	COG1175	transmembrane transport
FY150_00345	COG0395	ABC-type sugar transport system, permease component
FY150_00360	COG0427	acetyl-CoA hydrolase
FY150_00370	COG3938	Belongs to the proline racemase family
FY150_00375	COG0418	dihydroorotase activity
FY150_00380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY150_00400	COG0166	Belongs to the GPI family
FY150_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY150_00410	COG3842	ATPase activity
FY150_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY150_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY150_00425	COG4774	siderophore transport
FY150_00485	COG2326	polyphosphate kinase activity
FY150_00490	COG5002	protein histidine kinase activity
FY150_00495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY150_00500	COG0573	inorganic phosphate transmembrane transporter activity
FY150_00510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY150_00515	COG0704	Plays a role in the regulation of phosphate uptake
FY150_00520	COG0745	RESPONSE REGULATOR receiver
FY150_00530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY150_00535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY150_00545	COG2967	ApaG domain
FY150_00560	COG0717	Belongs to the dCTP deaminase family
FY150_00570	COG0582	viral genome integration into host DNA
FY150_00600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY150_00610	COG1278	Cold shock
FY150_00685	COG2972	Histidine kinase
FY150_00685	COG0840	transmembrane signaling receptor activity
FY150_00695	COG0640	Transcriptional regulator
FY150_00730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY150_00780	COG0167	dihydroorotate dehydrogenase activity
FY150_00795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY150_00815	COG1959	2 iron, 2 sulfur cluster binding
FY150_00820	COG1201	RNA secondary structure unwinding
FY150_00850	COG1960	acyl-CoA dehydrogenase activity
FY150_00855	COG0183	Belongs to the thiolase family
FY150_00860	COG1024	Enoyl-CoA hydratase
FY150_00860	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY150_00995	COG0582	viral genome integration into host DNA
FY150_01010	COG1320	monovalent cation:proton antiporter activity
FY150_01015	COG2212	antiporter activity
FY150_01020	COG1863	multisubunit Na H antiporter MnhE subunit
FY150_01025	COG0651	ATP synthesis coupled electron transport
FY150_01030	COG1006	Multisubunit Na H antiporter MnhC subunit
FY150_01035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY150_01035	COG2111	Na H antiporter
FY150_01045	COG0840	transmembrane signaling receptor activity
FY150_01055	COG0745	RESPONSE REGULATOR receiver
FY150_01060	COG2198	Histidine kinase
FY150_01060	COG0643	Histidine kinase
FY150_01065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY150_01070	COG2201	protein-glutamate methylesterase activity
FY150_01075	COG0745	RESPONSE REGULATOR receiver
FY150_01080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY150_01090	COG1766	The M ring may be actively involved in energy transduction
FY150_01095	COG2771	luxR family
FY150_01105	COG0840	transmembrane signaling receptor activity
FY150_01105	COG2972	Histidine kinase
FY150_01110	COG0784	Response regulator, receiver
FY150_01110	COG2198	Histidine kinase
FY150_01110	COG2205	protein histidine kinase activity
FY150_01115	COG1970	mechanosensitive ion channel activity
FY150_01120	COG0436	Aminotransferase
FY150_01135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY150_01140	COG0424	maF-like protein
FY150_01145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY150_01155	COG5328	Belongs to the UPF0262 family
FY150_01160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY150_01170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY150_01205	COG1338	Plays a role in the flagellum-specific transport system
FY150_01215	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY150_01225	COG1706	bacterial-type flagellum-dependent cell motility
FY150_01230	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY150_01235	COG4786	Flagellar basal body rod
FY150_01240	COG1677	Flagellar hook-basal body complex protein FliE
FY150_01245	COG1558	bacterial-type flagellum-dependent cell motility
FY150_01250	COG1815	bacterial-type flagellum-dependent cell motility
FY150_01260	COG1157	protein secretion by the type III secretion system
FY150_01265	COG4786	Flagellar basal body rod
FY150_01275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY150_01280	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY150_01285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY150_01290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY150_01295	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY150_01315	COG1360	Flagellar Motor Protein
FY150_01360	COG5443	negative regulation of bacterial-type flagellum assembly
FY150_01365	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY150_01375	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY150_01415	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY150_01420	COG1609	Transcriptional regulator
FY150_01425	COG1653	transport
FY150_01430	COG1175	transmembrane transport
FY150_01435	COG0395	ABC-type sugar transport system, permease component
FY150_01440	COG0366	Alpha amylase catalytic
FY150_01445	COG3842	ATPase activity
FY150_01460	COG0129	dihydroxy-acid dehydratase activity
FY150_01465	COG0363	glucosamine-6-phosphate deaminase activity
FY150_01470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY150_01475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_01485	COG2081	HI0933 family
FY150_01510	COG2224	Isocitrate lyase
FY150_01525	COG3842	ATPase activity
FY150_01530	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY150_01535	COG1177	transmembrane transport
FY150_01545	COG2205	protein histidine kinase activity
FY150_01570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_01585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY150_01590	COG1984	allophanate hydrolase subunit 2
FY150_01595	COG1802	Transcriptional regulator
FY150_01600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY150_01615	COG0006	proline dipeptidase activity
FY150_01640	COG0765	amino acid transport
FY150_01665	COG3665	Urea carboxylase-associated protein
FY150_01670	COG1116	anion transmembrane transporter activity
FY150_01695	COG0395	ABC-type sugar transport system, permease component
FY150_01700	COG3842	ATPase activity
FY150_01710	COG1063	alcohol dehydrogenase
FY150_01715	COG4948	Mandelate Racemase Muconate Lactonizing
FY150_01720	COG4948	Mandelate Racemase Muconate Lactonizing
FY150_01725	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_01730	COG0248	Ppx GppA phosphatase
FY150_01735	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY150_01740	COG0477	Major facilitator Superfamily
FY150_01770	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY150_01775	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY150_01785	COG0142	geranyltranstransferase activity
FY150_01820	COG0752	glycyl-tRNA synthetase alpha subunit
FY150_01830	COG1704	LemA family
FY150_01835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY150_01845	COG0751	glycine-tRNA ligase activity
FY150_01850	COG1683	Conserved Protein
FY150_01855	COG0840	transmembrane signaling receptor activity
FY150_01865	COG0151	Belongs to the GarS family
FY150_01870	COG2183	response to ionizing radiation
FY150_01875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY150_01885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY150_01900	COG0583	DNA-binding transcription factor activity
FY150_01920	COG0306	phosphate transporter
FY150_01930	COG0561	phosphatase activity
FY150_01935	COG0438	transferase activity, transferring glycosyl groups
FY150_01940	COG2186	Transcriptional regulator
FY150_01950	COG0583	DNA-binding transcription factor activity
FY150_01955	COG0277	FAD linked oxidase domain protein
FY150_01960	COG0277	FAD linked oxidase domain protein
FY150_01965	COG0247	lactate metabolic process
FY150_01975	COG1376	ErfK ybiS ycfS ynhG family protein
FY150_01980	COG2818	Glycosylase
FY150_01990	COG2855	membrane
FY150_01995	COG0583	DNA-binding transcription factor activity
FY150_02025	COG0124	histidyl-tRNA synthetase
FY150_02035	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY150_02040	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY150_02045	COG2259	Doxx family
FY150_02055	COG0459	protein refolding
FY150_02060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY150_02070	COG0196	riboflavin kinase activity
FY150_02075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY150_02085	COG0590	tRNA wobble adenosine to inosine editing
FY150_02090	COG1187	pseudouridine synthase activity
FY150_02095	COG0742	ribosomal rna small subunit methyltransferase
FY150_02100	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY150_02105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY150_02105	COG0475	glutathione-regulated potassium exporter activity
FY150_02110	COG0312	modulator of DNA gyrase
FY150_02115	COG0483	inositol monophosphate 1-phosphatase activity
FY150_02125	COG1519	Transferase
FY150_02135	COG1663	tetraacyldisaccharide 4'-kinase activity
FY150_02145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY150_02150	COG0745	RESPONSE REGULATOR receiver
FY150_02155	COG3300	MHYT domain
FY150_02155	COG5001	Diguanylate cyclase
FY150_02160	COG3386	PFAM SMP-30 Gluconolaconase
FY150_02165	COG0800	Aldolase
FY150_02170	COG3734	2-keto-3-deoxy-galactonokinase
FY150_02175	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_02185	COG2197	response regulator
FY150_02200	COG0598	Magnesium transport protein CorA
FY150_02205	COG3158	transport of potassium into the cell
FY150_02220	COG0356	it plays a direct role in the translocation of protons across the membrane
FY150_02230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY150_02235	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY150_02250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY150_02270	COG0009	L-threonylcarbamoyladenylate synthase
FY150_02280	COG4638	Rieske (2fe-2S)
FY150_02305	COG1960	acyl-CoA dehydrogenase activity
FY150_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY150_02330	COG0840	transmembrane signaling receptor activity
FY150_02360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY150_02365	COG1741	Belongs to the pirin family
FY150_02370	COG1722	exodeoxyribonuclease VII activity
FY150_02375	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY150_02380	COG1268	BioY protein
FY150_02385	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY150_02390	COG1122	ATPase activity
FY150_02395	COG3214	Protein conserved in bacteria
FY150_02400	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY150_02400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY150_02405	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY150_02425	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY150_02440	COG0259	pyridoxamine-phosphate oxidase activity
FY150_02470	COG0312	modulator of DNA gyrase
FY150_02485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY150_02490	COG0109	protoheme IX farnesyltransferase activity
FY150_02495	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY150_02510	COG3346	SURF1 family
FY150_02515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY150_02520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY150_02525	COG0328	RNA-DNA hybrid ribonuclease activity
FY150_02535	COG0678	peroxiredoxin activity
FY150_02535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY150_02545	COG1678	Uncharacterized ACR, COG1678
FY150_02560	COG3300	MHYT domain
FY150_02560	COG5001	Diguanylate cyclase
FY150_02565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY150_02570	COG0612	Peptidase, M16
FY150_02585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY150_02590	COG1802	Transcriptional regulator
FY150_02605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY150_02615	COG1194	a g-specific adenine glycosylase
FY150_02630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY150_02635	COG1196	nuclear chromosome segregation
FY150_02640	COG2514	catechol 2,3-dioxygenase activity
FY150_02645	COG0574	Belongs to the PEP-utilizing enzyme family
FY150_02645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY150_02655	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FY150_02665	COG1823	symporter activity
FY150_02690	COG0579	oxidoreductase
FY150_02705	COG2895	sulfate adenylyltransferase (ATP) activity
FY150_02710	COG0175	sulfate reduction
FY150_02715	COG0175	sulfate reduction
FY150_02720	COG1959	2 iron, 2 sulfur cluster binding
FY150_02725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY150_02730	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY150_02735	COG4208	sulfate ABC transporter
FY150_02740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY150_02760	COG2199	diguanylate cyclase activity
FY150_02760	COG2200	EAL domain
FY150_02760	COG2203	Gaf domain
FY150_02770	COG1309	transcriptional regulator
FY150_02775	COG1012	belongs to the aldehyde dehydrogenase family
FY150_02780	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY150_02825	COG0477	Major facilitator Superfamily
FY150_02835	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY150_02835	COG1793	dna ligase
FY150_02855	COG1376	ErfK ybiS ycfS ynhG family protein
FY150_02860	COG1376	ErfK ybiS ycfS ynhG family protein
FY150_02865	COG1846	Transcriptional regulator
FY150_02870	COG1764	response to oxidative stress
FY150_02885	COG0488	(ABC) transporter
FY150_02920	COG0583	DNA-binding transcription factor activity
FY150_02925	COG4221	oxidoreductase activity
FY150_02940	COG0433	COG0433 Predicted ATPase
FY150_02950	COG1733	regulation of RNA biosynthetic process
FY150_02955	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY150_02970	COG0656	L-ascorbic acid biosynthetic process
FY150_02975	COG3781	membrane
FY150_02980	COG2378	regulation of single-species biofilm formation
FY150_02990	COG4106	trans-aconitate 2-methyltransferase activity
FY150_02995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY150_03000	COG0583	DNA-binding transcription factor activity
FY150_03015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY150_03035	COG3909	cytochrome
FY150_03040	COG2010	Cytochrome c
FY150_03070	COG0789	Transcriptional regulator
FY150_03095	COG4175	Glycine betaine
FY150_03095	COG0517	IMP dehydrogenase activity
FY150_03100	COG4176	ABC-type proline glycine betaine transport system permease component
FY150_03120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_03130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY150_03130	COG2169	Transcriptional regulator
FY150_03140	COG2514	catechol 2,3-dioxygenase activity
FY150_03160	COG1272	protein, Hemolysin III
FY150_03170	COG1280	lysine exporter protein (LysE YggA)
FY150_03175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY150_03180	COG2111	Na H antiporter
FY150_03180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY150_03185	COG2111	Na H antiporter
FY150_03190	COG1006	Multisubunit Na H antiporter MnhC subunit
FY150_03195	COG0651	ATP synthesis coupled electron transport
FY150_03200	COG1863	multisubunit Na H antiporter MnhE subunit
FY150_03205	COG2212	antiporter activity
FY150_03210	COG1320	monovalent cation:proton antiporter activity
FY150_03215	COG4957	zinc ion binding
FY150_03230	COG2166	iron-sulfur cluster assembly
FY150_03240	COG2205	protein histidine kinase activity
FY150_03290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY150_03295	COG2983	Belongs to the UPF0260 family
FY150_03310	COG2217	Heavy metal translocating P-type atpase
FY150_03340	COG0477	Major facilitator Superfamily
FY150_03350	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY150_03400	COG4695	Portal protein
FY150_03505	COG4235	cytochrome complex assembly
FY150_03510	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY150_03515	COG1138	Cytochrome C-type biogenesis protein
FY150_03520	COG3088	subunit of a heme lyase
FY150_03525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY150_03530	COG0745	RESPONSE REGULATOR receiver
FY150_03535	COG2205	protein histidine kinase activity
FY150_03540	COG3011	Protein conserved in bacteria
FY150_03550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY150_03555	COG2202	Pas domain
FY150_03555	COG2205	protein histidine kinase activity
FY150_03565	COG0308	aminopeptidase N
FY150_03570	COG0697	spore germination
FY150_03585	COG0443	Heat shock 70 kDa protein
FY150_03615	COG1733	regulation of RNA biosynthetic process
FY150_03630	COG0604	alcohol dehydrogenase
FY150_03635	COG1733	regulation of RNA biosynthetic process
FY150_03640	COG1968	undecaprenyl-diphosphatase activity
FY150_03645	COG2239	Acts as a magnesium transporter
FY150_03650	COG2814	Major facilitator Superfamily
FY150_03675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY150_03700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY150_03705	COG2132	Multicopper oxidase
FY150_03750	COG0741	lytic transglycosylase activity
FY150_03755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_03760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY150_03765	COG0840	transmembrane signaling receptor activity
FY150_03775	COG1758	RNA polymerase activity
FY150_03795	COG0736	holo-[acyl-carrier-protein] synthase activity
FY150_03800	COG0681	Belongs to the peptidase S26 family
FY150_03805	COG0571	ribonuclease III activity
FY150_03810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY150_03820	COG0784	Response regulator, receiver
FY150_03825	COG1381	Involved in DNA repair and RecF pathway recombination
FY150_03845	COG1418	mRNA catabolic process
FY150_03855	COG0346	lactoylglutathione lyase activity
FY150_03870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_03875	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY150_03880	COG0668	transmembrane transport
FY150_03890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY150_03920	COG1742	UPF0060 membrane protein
FY150_03935	COG1183	phosphatidylcholine synthase activity
FY150_03940	COG0688	phosphatidylethanolamine metabolic process
FY150_03945	COG5265	(ABC) transporter
FY150_03985	COG2852	Protein conserved in bacteria
FY150_03990	COG0215	cysteine-tRNA ligase activity
FY150_03995	COG4221	oxidoreductase activity
FY150_04000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY150_04005	COG1286	toxin biosynthetic process
FY150_04025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY150_04035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY150_04045	COG5265	(ABC) transporter
FY150_04050	COG0305	Participates in initiation and elongation during chromosome replication
FY150_04070	COG0359	binds to the 23S rRNA
FY150_04080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY150_04085	COG0360	Binds together with S18 to 16S ribosomal RNA
FY150_04100	COG0667	Aldo Keto reductase
FY150_04105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY150_04115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY150_04120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY150_04125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY150_04130	COG1561	YicC-like family, N-terminal region
FY150_04135	COG0194	GDP metabolic process
FY150_04150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY150_04155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY150_04165	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY150_04180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY150_04200	COG5001	Diguanylate cyclase
FY150_04200	COG4251	negative regulation of phosphorylation
FY150_04200	COG3706	GGDEF domain
FY150_04200	COG2203	Gaf domain
FY150_04205	COG5001	Diguanylate cyclase
FY150_04205	COG3300	MHYT domain
FY150_04210	COG0488	(ABC) transporter
FY150_04215	COG3706	GGDEF domain
FY150_04225	COG0105	UTP biosynthetic process
FY150_04245	COG0314	molybdopterin synthase activity
FY150_04255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY150_04260	COG0322	excinuclease ABC activity
FY150_04265	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_04275	COG0625	glutathione transferase activity
FY150_04290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY150_04295	COG0243	molybdopterin cofactor binding
FY150_04310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY150_04315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY150_04325	COG0628	permease
FY150_04335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY150_04340	COG0248	Ppx GppA phosphatase
FY150_04365	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY150_04375	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY150_04380	COG0477	Major facilitator Superfamily
FY150_04385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY150_04395	COG0840	transmembrane signaling receptor activity
FY150_04400	COG0659	secondary active sulfate transmembrane transporter activity
FY150_04410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY150_04420	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY150_04430	COG0113	porphobilinogen synthase activity
FY150_04450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY150_04455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY150_04460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY150_04460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY150_04470	COG1280	lysine exporter protein (LysE YggA)
FY150_04475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY150_04480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY150_04485	COG2814	Major facilitator Superfamily
FY150_04490	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY150_04510	COG0416	fatty acid biosynthetic process
FY150_04515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY150_04520	COG0776	regulation of translation
FY150_04550	COG0789	Transcriptional regulator
FY150_04555	COG0601	transmembrane transport
FY150_04560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_04565	COG0444	Belongs to the ABC transporter superfamily
FY150_04585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY150_04590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY150_04605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY150_04610	COG0583	DNA-binding transcription factor activity
FY150_04620	COG0737	Belongs to the 5'-nucleotidase family
FY150_04645	COG2897	thiosulfate sulfurtransferase activity
FY150_04660	COG0415	Belongs to the DNA photolyase family
FY150_04670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY150_04700	COG3932	Exopolysaccharide synthesis, ExoD
FY150_04705	COG1238	metal cluster binding
FY150_04775	COG1612	heme a metabolic process
FY150_04785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY150_04790	COG0010	Belongs to the arginase family
FY150_04795	COG1396	sequence-specific DNA binding
FY150_04800	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FY150_04805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY150_04810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY150_04820	COG1832	CoA-binding protein
FY150_04830	COG1846	Transcriptional regulator
FY150_04855	COG2199	diguanylate cyclase activity
FY150_04860	COG0740	serine-type endopeptidase activity
FY150_04865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY150_04870	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY150_04880	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY150_04905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY150_04910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY150_04915	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY150_04925	COG0649	NAD binding
FY150_04935	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY150_04940	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY150_04950	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY150_04955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY150_04965	COG0713	ATP synthesis coupled electron transport
FY150_04980	COG1007	ATP synthesis coupled electron transport
FY150_04985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY150_04985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY150_05000	COG0442	prolyl-tRNA aminoacylation
FY150_05010	COG1136	(ABC) transporter
FY150_05025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY150_05045	COG0784	Response regulator, receiver
FY150_05055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY150_05060	COG0477	Major facilitator Superfamily
FY150_05075	COG0557	exoribonuclease II activity
FY150_05080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY150_05090	COG0758	DNA mediated transformation
FY150_05095	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY150_05105	COG0540	Belongs to the ATCase OTCase family
FY150_05115	COG1960	acyl-CoA dehydrogenase activity
FY150_05120	COG0456	acetyltransferase
FY150_05145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY150_05150	COG2824	Alkylphosphonate utilization operon protein PhnA
FY150_05155	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY150_05160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY150_05165	COG0154	amidase activity
FY150_05170	COG3811	Belongs to the UPF0386 family
FY150_05185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY150_05195	COG0456	acetyltransferase
FY150_05215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY150_05220	COG0439	Biotin carboxylase
FY150_05225	COG0511	ligase activity, forming carbon-carbon bonds
FY150_05230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY150_05240	COG0436	Aminotransferase
FY150_05260	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_05265	COG1530	ribonuclease E activity
FY150_05275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY150_05295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY150_05300	COG0384	phenazine biosynthesis protein PhzF
FY150_05315	COG0633	Ferredoxin
FY150_05325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY150_05330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY150_05335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY150_05345	COG3768	UPF0283 membrane protein
FY150_05350	COG3106	COG3106 Predicted ATPase
FY150_05380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY150_05410	COG0537	adenosine 5'-monophosphoramidase activity
FY150_05435	COG0052	Belongs to the universal ribosomal protein uS2 family
FY150_05440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY150_05445	COG0528	UMP kinase activity
FY150_05450	COG0233	cytoplasmic translational termination
FY150_05455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY150_05465	COG0750	zinc metalloprotease
FY150_05470	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY150_05475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY150_05480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY150_05485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY150_05490	COG3494	Protein of unknown function (DUF1009)
FY150_05495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY150_05500	COG2186	Transcriptional regulator
FY150_05510	COG0765	amino acid transport
FY150_05515	COG0765	amino acid transport
FY150_05525	COG0372	Belongs to the citrate synthase family
FY150_05540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY150_05565	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_05570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_05575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_05580	COG3958	Transketolase
FY150_05585	COG3959	Transketolase, thiamine diphosphate binding domain
FY150_05590	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_05595	COG0583	DNA-binding transcription factor activity
FY150_05605	COG2376	Dihydroxyacetone kinase
FY150_05610	COG1461	Dihydroxyacetone kinase
FY150_05625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY150_05630	COG0148	phosphopyruvate hydratase activity
FY150_05640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY150_05645	COG0022	dehydrogenase e1 component
FY150_05645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY150_05650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY150_05660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY150_05670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY150_05675	COG0697	spore germination
FY150_05690	COG2867	negative regulation of translational initiation
FY150_05695	COG1546	Belongs to the CinA family
FY150_05700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY150_05700	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY150_05710	COG3852	Histidine kinase
FY150_05715	COG2204	response regulator
FY150_05720	COG5000	phosphorelay sensor kinase activity
FY150_05725	COG2204	response regulator
FY150_05730	COG0569	domain protein
FY150_05735	COG1923	regulation of RNA biosynthetic process
FY150_05740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY150_05745	COG3956	TIGRFAM MazG family protein
FY150_05755	COG1648	precorrin-2 dehydrogenase activity
FY150_05755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY150_05790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY150_05790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY150_05795	COG0509	glycine decarboxylation via glycine cleavage system
FY150_05800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY150_05825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY150_05850	COG0251	oxidation-reduction process
FY150_05855	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY150_05865	COG1671	Belongs to the UPF0178 family
FY150_05875	COG0450	alkyl hydroperoxide reductase
FY150_05885	COG0625	glutathione transferase activity
FY150_05890	COG0454	-acetyltransferase
FY150_05890	COG0456	acetyltransferase
FY150_05910	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY150_05925	COG0436	Aminotransferase
FY150_05945	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_05950	COG3836	Belongs to the HpcH HpaI aldolase family
FY150_05985	COG0431	NADPH-dependent FMN reductase
FY150_05995	COG0798	PFAM Bile acid sodium symporter
FY150_06000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY150_06025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY150_06025	COG0321	lipoyl(octanoyl) transferase activity
FY150_06030	COG0084	hydrolase, TatD family'
FY150_06035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY150_06045	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY150_06095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY150_06100	COG2095	MarC family integral membrane protein
FY150_06105	COG0517	IMP dehydrogenase activity
FY150_06105	COG0617	tRNA 3'-terminal CCA addition
FY150_06105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY150_06115	COG0629	single-stranded DNA binding
FY150_06120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY150_06130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY150_06150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY150_06155	COG1121	(ABC) transporter
FY150_06175	COG0667	Aldo Keto reductase
FY150_06185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY150_06275	COG2239	Acts as a magnesium transporter
FY150_06280	COG0243	molybdopterin cofactor binding
FY150_06290	COG0242	peptide deformylase activity
FY150_06300	COG2205	protein histidine kinase activity
FY150_06300	COG2202	Pas domain
FY150_06310	COG0321	lipoyl(octanoyl) transferase activity
FY150_06315	COG1064	alcohol dehydrogenase
FY150_06345	COG1862	Preprotein translocase
FY150_06360	COG1309	transcriptional regulator
FY150_06365	COG2124	cytochrome p450
FY150_06380	COG0596	Alpha beta hydrolase
FY150_06390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY150_06395	COG0626	cystathionine gamma-synthase activity
FY150_06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_06405	COG4597	amino acid ABC transporter
FY150_06410	COG0765	amino acid transport
FY150_06415	COG1126	abc transporter atp-binding protein
FY150_06430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY150_06445	COG0436	Aminotransferase
FY150_06475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY150_06485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY150_06490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY150_06495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY150_06515	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY150_06520	COG1489	DNA binding
FY150_06525	COG0024	Methionine aminopeptidase
FY150_06530	COG2003	Belongs to the UPF0758 family
FY150_06545	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY150_06560	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY150_06565	COG0546	phosphoglycolate phosphatase activity
FY150_06575	COG0114	fumarate hydratase activity
FY150_06580	COG0504	CTP synthase activity
FY150_06590	COG0149	triose-phosphate isomerase activity
FY150_06600	COG0187	DNA topoisomerase II activity
FY150_06610	COG0740	serine-type endopeptidase activity
FY150_06620	COG0640	Transcriptional regulator
FY150_06625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY150_06630	COG0745	RESPONSE REGULATOR receiver
FY150_06640	COG3264	Mechanosensitive ion channel
FY150_06640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY150_06695	COG1127	ABC transporter
FY150_06700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY150_06705	COG4948	Mandelate Racemase Muconate Lactonizing
FY150_06715	COG0280	phosphate acetyltransferase
FY150_06715	COG0281	malic enzyme
FY150_06725	COG0778	Nitroreductase
FY150_06730	COG0823	Involved in the tonB-independent uptake of proteins
FY150_06745	COG1368	sulfuric ester hydrolase activity
FY150_06770	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY150_06790	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY150_06810	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY150_06825	COG0318	PFAM AMP-dependent synthetase and ligase
FY150_06835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY150_06835	COG0512	Glutamine amidotransferase of anthranilate synthase
FY150_06840	COG0343	queuine tRNA-ribosyltransferase activity
FY150_06845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY150_06860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY150_06875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY150_06880	COG0134	indole-3-glycerol-phosphate synthase activity
FY150_06885	COG0315	cyclic pyranopterin monophosphate synthase activity
FY150_06890	COG0303	'Molybdopterin
FY150_06895	COG3706	GGDEF domain
FY150_06905	COG0475	glutathione-regulated potassium exporter activity
FY150_06905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY150_06915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY150_06920	COG0697	spore germination
FY150_06925	COG2814	Major facilitator Superfamily
FY150_06930	COG0746	molybdenum cofactor guanylyltransferase activity
FY150_06935	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY150_06940	COG0739	heme binding
FY150_06945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY150_06950	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY150_06955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY150_06960	COG0805	protein transport
FY150_06965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY150_06970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY150_06975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY150_06980	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY150_06985	COG1472	Belongs to the glycosyl hydrolase 3 family
FY150_06995	COG0018	arginyl-trna synthetase
FY150_07000	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY150_07025	COG0525	valine-tRNA ligase activity
FY150_07035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY150_07065	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY150_07070	COG1058	Belongs to the CinA family
FY150_07070	COG1546	Belongs to the CinA family
FY150_07075	COG0589	response to stress
FY150_07080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY150_07085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY150_07155	COG0583	DNA-binding transcription factor activity
FY150_07160	COG1902	pentaerythritol trinitrate reductase activity
FY150_07165	COG0583	DNA-binding transcription factor activity
FY150_07170	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_07180	COG1335	isochorismatase
FY150_07185	COG0583	DNA-binding transcription factor activity
FY150_07190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY150_07270	COG1914	H( )-stimulated, divalent metal cation uptake system
FY150_07280	COG1132	(ABC) transporter
FY150_07285	COG0628	permease
FY150_07320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY150_07330	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY150_07340	COG0302	gtp cyclohydrolase
FY150_07345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY150_07350	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY150_07360	COG0516	GMP reductase activity
FY150_07360	COG0517	IMP dehydrogenase activity
FY150_07395	COG1760	l-serine dehydratase
FY150_07430	COG0583	DNA-binding transcription factor activity
FY150_07445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY150_07445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY150_07450	COG0347	Belongs to the P(II) protein family
FY150_07455	COG0174	glutamine synthetase
FY150_07485	COG0697	spore germination
FY150_07490	COG0300	oxidoreductase activity
FY150_07500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY150_07510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY150_07540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY150_07545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY150_07550	COG2186	Transcriptional regulator
FY150_07560	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY150_07565	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY150_07570	COG3845	ABC transporter
FY150_07575	COG1183	phosphatidylcholine synthase activity
FY150_07580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY150_07585	COG0679	Auxin Efflux Carrier
FY150_07590	COG0785	Cytochrome C biogenesis protein
FY150_07610	COG1278	Cold shock
FY150_07660	COG1136	(ABC) transporter
FY150_07660	COG0577	efflux transmembrane transporter activity
FY150_07665	COG1136	(ABC) transporter
FY150_07665	COG0577	efflux transmembrane transporter activity
FY150_07690	COG2151	metal-sulfur cluster biosynthetic enzyme
FY150_07695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY150_07700	COG0719	Fe-S assembly protein
FY150_07705	COG0396	ATPase activity
FY150_07715	COG0719	Fe-S assembly protein
FY150_07720	COG1104	cysteine desulfurase activity
FY150_07725	COG2945	thiolester hydrolase activity
FY150_07730	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY150_07735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY150_07745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY150_07750	COG2833	Protein of unknown function (DUF455)
FY150_07755	COG0739	heme binding
FY150_07760	COG0513	Belongs to the DEAD box helicase family
FY150_07785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY150_07795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY150_07800	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY150_07805	COG0047	phosphoribosylformylglycinamidine synthase activity
FY150_07820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY150_07825	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY150_07850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY150_07855	COG2814	Major facilitator Superfamily
FY150_07860	COG0483	inositol monophosphate 1-phosphatase activity
FY150_07865	COG0483	inositol monophosphate 1-phosphatase activity
FY150_07870	COG0037	tRNA processing
FY150_07875	COG2066	Belongs to the glutaminase family
FY150_07880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY150_07885	COG0861	Integral membrane protein TerC family
FY150_07900	COG1280	lysine exporter protein (LysE YggA)
FY150_07910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY150_07915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY150_07925	COG0538	isocitrate dehydrogenase activity
FY150_07935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY150_07940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY150_07945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_07950	COG2313	pseudouridylate synthase activity
FY150_07960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_07965	COG4215	(ABC) transporter
FY150_07975	COG5425	PFAM Usg family protein
FY150_07985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY150_07990	COG1522	sequence-specific DNA binding
FY150_07995	COG1573	uracil-dna glycosylase
FY150_08005	COG2205	protein histidine kinase activity
FY150_08005	COG2202	Pas domain
FY150_08015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY150_08020	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY150_08040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY150_08045	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_08050	COG1129	ABC transporter
FY150_08060	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_08065	COG3959	Transketolase, thiamine diphosphate binding domain
FY150_08070	COG3958	Transketolase
FY150_08075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY150_08080	COG2390	Transcriptional regulator
FY150_08090	COG0842	Transport permease protein
FY150_08095	COG1131	(ABC) transporter
FY150_08100	COG0730	response to heat
FY150_08100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY150_08120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY150_08125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY150_08145	COG0129	dihydroxy-acid dehydratase activity
FY150_08150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY150_08155	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY150_08165	COG0203	ribosomal protein L17
FY150_08170	COG0202	RNA polymerase activity
FY150_08175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY150_08180	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY150_08185	COG0563	adenylate kinase activity
FY150_08190	COG0201	protein transport
FY150_08195	COG0200	Binds to the 23S rRNA
FY150_08200	COG1841	ribosomal large subunit assembly
FY150_08205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY150_08210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY150_08215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY150_08220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY150_08225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY150_08230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY150_08235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY150_08240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY150_08245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY150_08250	COG0255	Belongs to the universal ribosomal protein uL29 family
FY150_08255	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY150_08260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY150_08265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY150_08270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY150_08275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY150_08280	COG0089	rRNA binding
FY150_08285	COG0088	Forms part of the polypeptide exit tunnel
FY150_08290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY150_08295	COG0051	transcription antitermination factor activity, RNA binding
FY150_08300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY150_08305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY150_08310	COG0049	tRNA binding
FY150_08315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY150_08335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY150_08340	COG0085	RNA polymerase activity
FY150_08345	COG0222	ribosome binding
FY150_08350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY150_08355	COG0081	regulation of translation
FY150_08360	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY150_08370	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY150_08385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY150_08390	COG0861	Integral membrane protein TerC family
FY150_08395	COG3895	Periplasmic Protein
FY150_08425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY150_08430	COG1607	acyl-coa hydrolase
FY150_08450	COG2910	NAD(P)H-binding
FY150_08455	COG1733	regulation of RNA biosynthetic process
FY150_08470	COG0556	nucleotide-excision repair
FY150_08495	COG0484	heat shock protein binding
FY150_08530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY150_08535	COG1840	ABC-type Fe3 transport system, periplasmic component
FY150_08540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY150_08555	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY150_08565	COG2207	Transcriptional regulator
FY150_08570	COG1064	alcohol dehydrogenase
FY150_08575	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY150_08580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY150_08585	COG2197	response regulator
FY150_08590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY150_08625	COG0656	L-ascorbic acid biosynthetic process
FY150_08645	COG0440	acetolactate synthase activity
FY150_08650	COG0028	Belongs to the TPP enzyme family
FY150_08660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY150_08665	COG0560	Phosphoserine phosphatase
FY150_08665	COG3830	Belongs to the UPF0237 family
FY150_08675	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_08685	COG0330	HflC and HflK could
FY150_08690	COG0330	HflC and HflK could
FY150_08700	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY150_08740	COG0277	FAD linked oxidase domain protein
FY150_08745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY150_08785	COG1335	isochorismatase
FY150_08805	COG0006	proline dipeptidase activity
FY150_08810	COG2264	protein methyltransferase activity
FY150_08815	COG1999	signal sequence binding
FY150_08825	COG0835	chemotaxis
FY150_08835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY150_08840	COG0583	DNA-binding transcription factor activity
FY150_08850	COG1247	-acetyltransferase
FY150_08860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY150_08875	COG0497	DNA recombination
FY150_08880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY150_08890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY150_08895	COG0849	cell division
FY150_08900	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY150_08905	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY150_08910	COG0477	Major facilitator Superfamily
FY150_08915	COG3300	MHYT domain
FY150_08915	COG5001	Diguanylate cyclase
FY150_08920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY150_08925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY150_08930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY150_08940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY150_08945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY150_08955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY150_08970	COG0275	rRNA processing
FY150_08975	COG2001	Belongs to the MraZ family
FY150_08990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_09000	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY150_09005	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FY150_09030	COG4106	trans-aconitate 2-methyltransferase activity
FY150_09050	COG2226	methyltransferase
FY150_09060	COG2267	carboxylic ester hydrolase activity
FY150_09065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY150_09095	COG1376	ErfK ybiS ycfS ynhG family protein
FY150_09100	COG2814	Major facilitator Superfamily
FY150_09135	COG1012	belongs to the aldehyde dehydrogenase family
FY150_09140	COG0174	glutamine synthetase
FY150_09145	COG0531	amino acid
FY150_09155	COG1737	Transcriptional regulator
FY150_09160	COG1840	ABC-type Fe3 transport system, periplasmic component
FY150_09175	COG3842	ATPase activity
FY150_09240	COG2968	Membrane
FY150_09250	COG0432	Pfam Uncharacterised protein family UPF0047
FY150_09265	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY150_09270	COG0358	DNA primase activity
FY150_09280	COG0505	Belongs to the CarA family
FY150_09285	COG0534	Mate efflux family protein
FY150_09300	COG2321	neutral zinc metallopeptidase
FY150_09315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY150_09325	COG3706	GGDEF domain
FY150_09340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY150_09350	COG1522	sequence-specific DNA binding
FY150_09355	COG0492	ferredoxin-NADP+ reductase activity
FY150_09360	COG0583	DNA-binding transcription factor activity
FY150_09370	COG1902	pentaerythritol trinitrate reductase activity
FY150_09395	COG0387	Pfam Sodium calcium exchanger
FY150_09400	COG0436	Aminotransferase
FY150_09405	COG2200	EAL domain
FY150_09405	COG2199	diguanylate cyclase activity
FY150_09420	COG1278	Cold shock
FY150_09425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY150_09435	COG1846	Transcriptional regulator
FY150_09440	COG0745	RESPONSE REGULATOR receiver
FY150_09445	COG2205	protein histidine kinase activity
FY150_09450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY150_09470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY150_09480	COG1496	oxidoreductase activity
FY150_09485	COG0006	proline dipeptidase activity
FY150_09495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY150_09520	COG0840	transmembrane signaling receptor activity
FY150_09525	COG1012	belongs to the aldehyde dehydrogenase family
FY150_09530	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY150_09535	COG5001	Diguanylate cyclase
FY150_09535	COG3300	MHYT domain
FY150_09540	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY150_09545	COG5001	Diguanylate cyclase
FY150_09555	COG0193	aminoacyl-tRNA hydrolase activity
FY150_09565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY150_09585	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY150_09595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY150_09595	COG2857	Cytochrome c1
FY150_09615	COG1132	(ABC) transporter
FY150_09620	COG1132	(ABC) transporter
FY150_09625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY150_09630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY150_09645	COG0408	coproporphyrinogen oxidase activity
FY150_09660	COG0617	tRNA 3'-terminal CCA addition
FY150_09675	COG0714	Associated with various cellular activities
FY150_09695	COG0454	-acetyltransferase
FY150_09710	COG0477	Major facilitator Superfamily
FY150_09720	COG0435	Glutathione S-transferase
FY150_09725	COG0494	nUDIX hydrolase
FY150_09735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY150_09750	COG3135	benzoate transporter
FY150_09775	COG0740	serine-type endopeptidase activity
FY150_09790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY150_09795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY150_09820	COG4175	Glycine betaine
FY150_09840	COG1435	thymidine kinase activity
FY150_09860	COG2862	Uncharacterized protein family, UPF0114
FY150_09865	COG1629	transport
FY150_09865	COG4771	TonB-dependent receptor
FY150_09875	COG0512	Glutamine amidotransferase of anthranilate synthase
FY150_09875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY150_09890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY150_09905	COG0366	Alpha amylase catalytic
FY150_09910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_09935	COG1160	GTP binding
FY150_09955	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY150_09965	COG0024	Methionine aminopeptidase
FY150_09975	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_09985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY150_09995	COG0583	DNA-binding transcription factor activity
FY150_10010	COG0402	S-adenosylhomocysteine deaminase activity
FY150_10020	COG1304	FMN binding
FY150_10030	COG1309	transcriptional regulator
FY150_10035	COG1686	Belongs to the peptidase S11 family
FY150_10045	COG2351	hydroxyisourate hydrolase activity
FY150_10050	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY150_10085	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY150_10100	COG5002	protein histidine kinase activity
FY150_10100	COG2205	protein histidine kinase activity
FY150_10100	COG0784	Response regulator, receiver
FY150_10105	COG0513	Belongs to the DEAD box helicase family
FY150_10115	COG2259	Doxx family
FY150_10120	COG1376	ErfK ybiS ycfS ynhG family protein
FY150_10130	COG2308	Evidence 4 Homologs of previously reported genes of
FY150_10140	COG1305	Transglutaminase-like
FY150_10165	COG4214	carbohydrate transport
FY150_10175	COG4213	ABC transporter substrate-binding protein
FY150_10230	COG0840	transmembrane signaling receptor activity
FY150_10235	COG1410	methionine synthase
FY150_10235	COG0646	methionine synthase
FY150_10280	COG1215	transferase activity, transferring glycosyl groups
FY150_10310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY150_10315	COG2346	COG2346, Truncated hemoglobins
FY150_10335	COG1309	transcriptional regulator
FY150_10350	COG0494	nUDIX hydrolase
FY150_10360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_10365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_10390	COG1234	tRNA 3'-trailer cleavage
FY150_10395	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY150_10400	COG0830	nickel cation binding
FY150_10405	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY150_10425	COG0804	urea catabolic process
FY150_10430	COG1442	glycosyl transferase family 8
FY150_10435	COG3755	Protein conserved in bacteria
FY150_10445	COG0832	Belongs to the urease beta subunit family
FY150_10450	COG3813	Protein conserved in bacteria
FY150_10455	COG0831	urea catabolic process
FY150_10460	COG0829	nickel cation binding
FY150_10485	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY150_10500	COG0174	glutamine synthetase
FY150_10505	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_10510	COG0784	Response regulator, receiver
FY150_10510	COG2198	Histidine kinase
FY150_10510	COG5002	protein histidine kinase activity
FY150_10555	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY150_10630	COG0564	pseudouridine synthase activity
FY150_10640	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY150_10650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY150_10675	COG0346	lactoylglutathione lyase activity
FY150_10685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY150_10695	COG2832	Protein of unknown function (DUF454)
FY150_10700	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY150_10705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_10710	COG4558	Periplasmic binding protein
FY150_10720	COG3721	Heme iron utilization protein
FY150_10735	COG3657	addiction module killer protein
FY150_10745	COG2205	protein histidine kinase activity
FY150_10785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_10790	COG4605	iron ion homeostasis
FY150_10795	COG4604	ABC transporter, ATP-binding protein
FY150_10800	COG0783	Belongs to the Dps family
FY150_10815	COG0656	L-ascorbic acid biosynthetic process
FY150_10820	COG2814	Major facilitator Superfamily
FY150_10830	COG0583	DNA-binding transcription factor activity
FY150_10835	COG0657	acetylesterase activity
FY150_10840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_10860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY150_10865	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY150_10870	COG0288	reversible hydration of carbon dioxide
FY150_10880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY150_10895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY150_10900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY150_10905	COG0778	Nitroreductase
FY150_10910	COG2267	carboxylic ester hydrolase activity
FY150_10915	COG0251	oxidation-reduction process
FY150_10920	COG1335	isochorismatase
FY150_10925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_10935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_10950	COG1175	transmembrane transport
FY150_10955	COG0395	ABC-type sugar transport system, permease component
FY150_10960	COG3842	ATPase activity
FY150_10965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_10990	COG4608	Belongs to the ABC transporter superfamily
FY150_10995	COG0444	Belongs to the ABC transporter superfamily
FY150_11000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_11005	COG0601	transmembrane transport
FY150_11060	COG2159	amidohydrolase
FY150_11065	COG1960	acyl-CoA dehydrogenase activity
FY150_11090	COG0450	alkyl hydroperoxide reductase
FY150_11115	COG0745	RESPONSE REGULATOR receiver
FY150_11125	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY150_11125	COG1902	pentaerythritol trinitrate reductase activity
FY150_11130	COG3842	ATPase activity
FY150_11140	COG1840	ABC-type Fe3 transport system, periplasmic component
FY150_11145	COG1840	ABC-type Fe3 transport system, periplasmic component
FY150_11150	COG0745	RESPONSE REGULATOR receiver
FY150_11160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY150_11165	COG0583	DNA-binding transcription factor activity
FY150_11175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY150_11195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY150_11230	COG4208	sulfate ABC transporter
FY150_11245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_11255	COG3842	ATPase activity
FY150_11260	COG0583	DNA-binding transcription factor activity
FY150_11295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY150_11300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY150_11305	COG1454	alcohol dehydrogenase
FY150_11355	COG1573	uracil-dna glycosylase
FY150_11415	COG3685	Protein conserved in bacteria
FY150_11420	COG0753	catalase activity
FY150_11445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY150_11450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY150_11460	COG2706	6-phosphogluconolactonase activity
FY150_11520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY150_11530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_11535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY150_11545	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY150_11550	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY150_11555	COG1509	lysine 2,3-aminomutase activity
FY150_11570	COG0583	DNA-binding transcription factor activity
FY150_11575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_11580	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY150_11585	COG4149	molybdate abc transporter
FY150_11590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY150_11605	COG2022	thiamine diphosphate biosynthetic process
FY150_11620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY150_11625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY150_11635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY150_11660	COG1132	(ABC) transporter
FY150_11665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY150_11710	COG4166	transmembrane transport
FY150_11720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_11730	COG0438	transferase activity, transferring glycosyl groups
FY150_11735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY150_11740	COG3142	Participates in the control of copper homeostasis
FY150_11745	COG2814	Major facilitator Superfamily
FY150_11760	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_11765	COG1737	Transcriptional regulator
FY150_11775	COG3842	ATPase activity
FY150_11785	COG0395	ABC-type sugar transport system, permease component
FY150_11805	COG2188	Transcriptional regulator
FY150_11810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY150_11815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY150_11820	COG1940	carbohydrate kinase activity
FY150_11830	COG0671	phosphoesterase, PA-phosphatase related
FY150_11835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY150_11840	COG0156	8-amino-7-oxononanoate synthase activity
FY150_11850	COG0729	surface antigen
FY150_11860	COG0835	chemotaxis
FY150_11870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY150_11875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY150_11880	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY150_11885	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY150_11890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY150_11895	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY150_11910	COG4974	Belongs to the 'phage' integrase family
FY150_11935	COG1280	lysine exporter protein (LysE YggA)
FY150_11945	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY150_11950	COG0567	Dehydrogenase, E1 component
FY150_11955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY150_11960	COG0045	succinate-CoA ligase (ADP-forming) activity
FY150_11965	COG0039	L-malate dehydrogenase activity
FY150_11970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY150_12005	COG2264	protein methyltransferase activity
FY150_12020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY150_12025	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY150_12030	COG0181	hydroxymethylbilane synthase activity
FY150_12070	COG1872	DUF167
FY150_12075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY150_12085	COG1217	gtp-binding protein TYPA
FY150_12090	COG0339	signal peptide processing
FY150_12100	COG1846	Transcriptional regulator
FY150_12110	COG0137	argininosuccinate synthase activity
FY150_12120	COG1280	lysine exporter protein (LysE YggA)
FY150_12125	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY150_12130	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY150_12140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY150_12155	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY150_12160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY150_12165	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY150_12175	COG4181	ATPase activity
FY150_12185	COG0670	Belongs to the BI1 family
FY150_12200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY150_12205	COG4133	protoheme IX ABC transporter activity
FY150_12210	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY150_12215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY150_12240	COG2917	probably involved in intracellular septation
FY150_12245	COG0552	protein localization to endoplasmic reticulum
FY150_12250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY150_12255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY150_12265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY150_12270	COG0287	Prephenate dehydrogenase
FY150_12270	COG1605	Chorismate mutase
FY150_12275	COG0228	four-way junction DNA binding
FY150_12280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY150_12285	COG0336	Belongs to the RNA methyltransferase TrmD family
FY150_12295	COG0335	large ribosomal subunit rRNA binding
FY150_12300	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY150_12305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_12320	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY150_12330	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY150_12350	COG0488	(ABC) transporter
FY150_12360	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY150_12370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY150_12375	COG0142	geranyltranstransferase activity
FY150_12380	COG2885	chlorophyll binding
FY150_12385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY150_12390	COG2223	nitrite transmembrane transporter activity
FY150_12395	COG1349	DNA-binding transcription factor activity
FY150_12400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY150_12405	COG2197	response regulator
FY150_12410	COG1132	(ABC) transporter
FY150_12420	COG3459	Glycosyltransferase 36 associated
FY150_12425	COG1473	amidohydrolase
FY150_12430	COG0579	oxidoreductase
FY150_12440	COG0129	dihydroxy-acid dehydratase activity
FY150_12445	COG2084	Dehydrogenase
FY150_12450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY150_12455	COG0277	FAD linked oxidase domain protein
FY150_12460	COG2186	Transcriptional regulator
FY150_12470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY150_12475	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_12480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_12485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY150_12495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY150_12500	COG0495	leucyl-tRNA aminoacylation
FY150_12515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY150_12520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY150_12530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY150_12535	COG1946	Acyl-CoA thioesterase
FY150_12540	COG0347	Belongs to the P(II) protein family
FY150_12545	COG0004	ammonium transporteR
FY150_12550	COG1674	ftsk spoiiie
FY150_12555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY150_12570	COG0745	RESPONSE REGULATOR receiver
FY150_12580	COG1329	Transcriptional regulator
FY150_12590	COG2270	Major facilitator Superfamily
FY150_12605	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_12620	COG0494	nUDIX hydrolase
FY150_12625	COG2861	carbohydrate metabolic process
FY150_12630	COG0793	Belongs to the peptidase S41A family
FY150_12640	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY150_12645	COG0799	negative regulation of ribosome biogenesis
FY150_12650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY150_12655	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY150_12660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY150_12665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY150_12680	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY150_12685	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY150_12700	COG2301	Belongs to the HpcH HpaI aldolase family
FY150_12710	COG0066	3-isopropylmalate dehydratase activity
FY150_12715	COG0473	3-isopropylmalate dehydrogenase activity
FY150_12720	COG1858	cytochrome C peroxidase
FY150_12725	COG1797	cobyrinic acid a,c-diamide synthase activity
FY150_12735	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY150_12800	COG1492	cobalamin metabolic process
FY150_12815	COG4948	Mandelate Racemase Muconate Lactonizing
FY150_12820	COG3254	rhamnose metabolic process
FY150_12825	COG0246	Mannitol dehydrogenase
FY150_12830	COG1063	alcohol dehydrogenase
FY150_12850	COG4214	carbohydrate transport
FY150_12855	COG1129	ABC transporter
FY150_12860	COG2186	Transcriptional regulator
FY150_12865	COG2721	sulfolactate sulfo-lyase activity
FY150_12870	COG0138	bifunctional purine biosynthesis protein purh
FY150_12880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY150_12880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY150_12885	COG0501	Belongs to the peptidase M48B family
FY150_12905	COG0357	Ribosomal RNA small subunit methyltransferase G
FY150_12910	COG0445	tRNA wobble uridine modification
FY150_12915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY150_12920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY150_12925	COG1981	membrane
FY150_12930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY150_12935	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY150_12940	COG0424	maF-like protein
FY150_12945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY150_12950	COG0237	dephospho-CoA kinase activity
FY150_12960	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY150_12965	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY150_12975	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY150_13000	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY150_13015	COG0135	phosphoribosylanthranilate isomerase activity
FY150_13020	COG0133	tryptophan synthase activity
FY150_13025	COG0159	tryptophan synthase activity
FY150_13030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY150_13035	COG0285	dihydrofolate synthase activity
FY150_13055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY150_13065	COG2205	protein histidine kinase activity
FY150_13070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY150_13075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY150_13080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY150_13080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY150_13085	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY150_13090	COG0642	Histidine kinase
FY150_13095	COG0745	RESPONSE REGULATOR receiver
FY150_13100	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY150_13110	COG1652	LysM domain
FY150_13115	COG1072	(Pantothenic acid kinase))
FY150_13120	COG0140	phosphoribosyl-ATP diphosphatase activity
FY150_13125	COG0107	imidazoleglycerol-phosphate synthase activity
FY150_13130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY150_13135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY150_13145	COG0131	Imidazoleglycerol-phosphate dehydratase
FY150_13150	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY150_13155	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY150_13165	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY150_13180	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY150_13190	COG1643	Atp-dependent helicase
FY150_13250	COG1072	(Pantothenic acid kinase))
FY150_13260	COG1780	Probably involved in ribonucleotide reductase function
FY150_13280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY150_13305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_13320	COG1185	polyribonucleotide nucleotidyltransferase activity
FY150_13325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY150_13330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY150_13335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY150_13340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY150_13340	COG3064	Membrane
FY150_13355	COG0779	Required for maturation of 30S ribosomal subunits
FY150_13360	COG2814	Major facilitator Superfamily
FY150_13365	COG2951	lytic endotransglycosylase activity
FY150_13370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY150_13380	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY150_13385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY150_13400	COG2816	NAD+ diphosphatase activity
FY150_13405	COG0077	Prephenate dehydratase
FY150_13405	COG1605	Chorismate mutase
FY150_13410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY150_13415	COG3474	cytochrome
FY150_13425	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY150_13430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY150_13435	COG1278	Cold shock
FY150_13440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY150_13450	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY150_13450	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY150_13460	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY150_13490	COG2900	Belongs to the SlyX family
FY150_13500	COG0484	heat shock protein binding
FY150_13505	COG0443	Heat shock 70 kDa protein
FY150_13520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY150_13525	COG1744	ABC transporter substrate-binding protein PnrA-like
FY150_13530	COG3845	ABC transporter
FY150_13535	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY150_13540	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY150_13545	COG0295	cytidine deaminase activity
FY150_13550	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY150_13555	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY150_13560	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY150_13570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY150_13575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY150_13580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY150_13590	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY150_13595	COG1845	cytochrome c oxidase, subunit III
FY150_13600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY150_13610	COG0477	Major facilitator Superfamily
FY150_13615	COG0067	glutamate synthase
FY150_13615	COG0069	glutamate synthase activity
FY150_13615	COG0070	glutamate synthase
FY150_13620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY150_13635	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY150_13645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY150_13675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_13695	COG0848	biopolymer transport protein
FY150_13705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY150_13720	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY150_13725	COG3454	Phosphonate metabolism
FY150_13730	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY150_13735	COG3639	organic phosphonate transmembrane transporter activity
FY150_13740	COG3639	organic phosphonate transmembrane transporter activity
FY150_13750	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY150_13760	COG4778	phosphonate C-P lyase system protein PhnL
FY150_13765	COG4107	phosphonate C-P lyase system protein PhnK
FY150_13770	COG3627	carbon phosphorus lyase activity
FY150_13775	COG3626	phosphonate metabolism
FY150_13780	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY150_13785	COG3624	Phosphonate C-P lyase system protein PhnG
FY150_13790	COG2188	Transcriptional regulator
FY150_13795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY150_13800	COG0837	glucose binding
FY150_13805	COG1803	Methylglyoxal synthase
FY150_13810	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY150_13815	COG4166	transmembrane transport
FY150_13820	COG4174	ABC transporter (Permease)
FY150_13825	COG4239	(ABC) transporter, permease
FY150_13830	COG4172	Belongs to the ABC transporter superfamily
FY150_13835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_13840	COG0174	glutamine synthetase
FY150_13845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_13850	COG3265	gluconokinase activity
FY150_13855	COG1174	glycine betaine transport
FY150_13860	COG1125	glycine betaine transport
FY150_13865	COG1174	glycine betaine transport
FY150_13870	COG1732	Glycine betaine
FY150_13880	COG1959	2 iron, 2 sulfur cluster binding
FY150_13885	COG1840	ABC-type Fe3 transport system, periplasmic component
FY150_13900	COG0697	spore germination
FY150_13915	COG0791	NLP P60 protein
FY150_13925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY150_13930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY150_13965	COG4964	Belongs to the GSP D family
FY150_14010	COG3422	double-strand break repair
FY150_14015	COG3757	hydrolase, family 25
FY150_14020	COG0697	spore germination
FY150_14025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY150_14060	COG0481	GTPase activity
FY150_14065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY150_14080	COG1396	sequence-specific DNA binding
FY150_14095	COG1917	Cupin 2, conserved barrel domain protein
FY150_14095	COG2169	Transcriptional regulator
FY150_14100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY150_14125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY150_14130	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY150_14135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY150_14145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY150_14150	COG0072	phenylalanine-tRNA ligase activity
FY150_14150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY150_14155	COG0667	Aldo Keto reductase
FY150_14175	COG2207	Transcriptional regulator
FY150_14200	COG1570	exodeoxyribonuclease VII activity
FY150_14215	COG1846	Transcriptional regulator
FY150_14220	COG0697	spore germination
FY150_14225	COG2309	aminopeptidase activity
FY150_14235	COG1393	Belongs to the ArsC family
FY150_14250	COG1309	transcriptional regulator
FY150_14260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY150_14260	COG0519	Catalyzes the synthesis of GMP from XMP
FY150_14275	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY150_14305	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY150_14315	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY150_14325	COG1968	undecaprenyl-diphosphatase activity
FY150_14340	COG0284	orotidine-5'-phosphate decarboxylase activity
FY150_14350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY150_14360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY150_14365	COG0792	nuclease activity
FY150_14380	COG1175	transmembrane transport
FY150_14390	COG3842	ATPase activity
FY150_14400	COG0189	ligase activity
FY150_14410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY150_14415	COG1280	lysine exporter protein (LysE YggA)
FY150_14420	COG0756	dUTP diphosphatase activity
FY150_14425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY150_14430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY150_14445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY150_14450	COG2226	methyltransferase
FY150_14455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY150_14460	COG1024	Enoyl-CoA hydratase
FY150_14465	COG0268	Binds directly to 16S ribosomal RNA
FY150_14475	COG1204	response to ionizing radiation
FY150_14490	COG0640	Transcriptional regulator
FY150_14505	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_14515	COG0395	ABC-type sugar transport system, permease component
FY150_14540	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_14545	COG1349	DNA-binding transcription factor activity
FY150_14550	COG1069	ribulokinase activity
FY150_14570	COG1846	Transcriptional regulator
FY150_14570	COG1940	carbohydrate kinase activity
FY150_14585	COG4178	(ABC) transporter
FY150_14590	COG0596	Alpha beta hydrolase
FY150_14595	COG2814	Major facilitator Superfamily
FY150_14600	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FY150_14605	COG1522	sequence-specific DNA binding
FY150_14610	COG1012	belongs to the aldehyde dehydrogenase family
FY150_14615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY150_14620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY150_14625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY150_14630	COG2423	ornithine cyclodeaminase activity
FY150_14635	COG0006	proline dipeptidase activity
FY150_14640	COG3608	succinylglutamate desuccinylase aspartoacylase
FY150_14645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_14650	COG0765	amino acid transport
FY150_14655	COG0765	amino acid transport
FY150_14660	COG1126	abc transporter atp-binding protein
FY150_14670	COG1082	Xylose isomerase domain protein TIM barrel
FY150_14685	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_14690	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_14695	COG1129	ABC transporter
FY150_14715	COG0110	maltose O-acetyltransferase activity
FY150_14720	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY150_14745	COG0488	(ABC) transporter
FY150_14750	COG5265	(ABC) transporter
FY150_14755	COG3181	Tripartite tricarboxylate transporter family receptor
FY150_14770	COG3237	CsbD-like
FY150_14790	COG0395	ABC-type sugar transport system, permease component
FY150_14795	COG3842	ATPase activity
FY150_14805	COG0483	inositol monophosphate 1-phosphatase activity
FY150_14815	COG0405	Gamma-glutamyltransferase
FY150_14820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_14825	COG0601	transmembrane transport
FY150_14830	COG0747	negative chemotaxis
FY150_14835	COG2186	Transcriptional regulator
FY150_14845	COG4948	Mandelate Racemase Muconate Lactonizing
FY150_14850	COG4172	Belongs to the ABC transporter superfamily
FY150_14855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_14860	COG0601	transmembrane transport
FY150_14865	COG0747	negative chemotaxis
FY150_14880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_14885	COG2223	nitrite transmembrane transporter activity
FY150_14895	COG3383	formate dehydrogenase (NAD+) activity
FY150_14915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY150_14930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY150_14940	COG0765	amino acid transport
FY150_14945	COG0765	amino acid transport
FY150_14965	COG3938	Belongs to the proline racemase family
FY150_14975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_14985	COG0765	amino acid transport
FY150_15000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY150_15005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_15015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY150_15020	COG0784	Response regulator, receiver
FY150_15035	COG0842	Transport permease protein
FY150_15040	COG1129	ABC transporter
FY150_15040	COG0842	Transport permease protein
FY150_15045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_15050	COG1486	melibiose metabolic process
FY150_15055	COG4172	Belongs to the ABC transporter superfamily
FY150_15060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_15065	COG0601	transmembrane transport
FY150_15070	COG0747	negative chemotaxis
FY150_15075	COG1486	melibiose metabolic process
FY150_15100	COG1940	carbohydrate kinase activity
FY150_15105	COG2182	Extracellular solute-binding protein
FY150_15110	COG1175	transmembrane transport
FY150_15115	COG0395	ABC-type sugar transport system, permease component
FY150_15120	COG0165	Argininosuccinate lyase
FY150_15125	COG3842	ATPase activity
FY150_15130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_15135	COG3119	arylsulfatase activity
FY150_15145	COG0583	DNA-binding transcription factor activity
FY150_15150	COG1012	belongs to the aldehyde dehydrogenase family
FY150_15185	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY150_15190	COG1120	ATPase activity
FY150_15195	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_15200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_15210	COG4774	siderophore transport
FY150_15220	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY150_15235	COG2205	protein histidine kinase activity
FY150_15245	COG1566	PFAM secretion protein HlyD family protein
FY150_15260	COG1392	Phosphate transport regulator
FY150_15265	COG0306	phosphate transporter
FY150_15270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY150_15280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY150_15290	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_15295	COG5001	Diguanylate cyclase
FY150_15295	COG3300	MHYT domain
FY150_15315	COG2186	Transcriptional regulator
FY150_15320	COG0601	transmembrane transport
FY150_15325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_15330	COG0444	Belongs to the ABC transporter superfamily
FY150_15335	COG4608	Belongs to the ABC transporter superfamily
FY150_15340	COG0210	DNA helicase
FY150_15365	COG0572	uridine kinase
FY150_15375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY150_15385	COG0463	Glycosyl transferase, family 2
FY150_15420	COG0297	glycogen (starch) synthase activity
FY150_15430	COG1132	(ABC) transporter
FY150_15435	COG2942	2-epimerase
FY150_15445	COG0583	DNA-binding transcription factor activity
FY150_15450	COG0667	Aldo Keto reductase
FY150_15455	COG0385	Bile acid
FY150_15500	COG3210	domain, Protein
FY150_15500	COG3210	domain, Protein
FY150_15525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY150_15540	COG0300	oxidoreductase activity
FY150_15545	COG0584	glycerophosphoryl diester phosphodiesterase
FY150_15550	COG1940	carbohydrate kinase activity
FY150_15560	COG3712	iron ion homeostasis
FY150_15565	COG4774	siderophore transport
FY150_15570	COG2814	Major facilitator Superfamily
FY150_15590	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY150_15605	COG1175	transmembrane transport
FY150_15610	COG0395	ABC-type sugar transport system, permease component
FY150_15615	COG1609	Transcriptional regulator
FY150_15620	COG1846	Transcriptional regulator
FY150_15630	COG0523	cobalamin synthesis protein
FY150_15665	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY150_15685	COG0800	Aldolase
FY150_15690	COG2954	triphosphatase activity
FY150_15700	COG1054	Belongs to the UPF0176 family
FY150_15705	COG5001	Diguanylate cyclase
FY150_15705	COG3300	MHYT domain
FY150_15715	COG2011	ABC-type metal ion transport system permease component
FY150_15720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY150_15725	COG0778	Nitroreductase
FY150_15735	COG2115	Belongs to the xylose isomerase family
FY150_15740	COG1070	Carbohydrate kinase
FY150_15745	COG1609	Transcriptional regulator
FY150_15760	COG1309	transcriptional regulator
FY150_15765	COG1253	flavin adenine dinucleotide binding
FY150_15775	COG0471	metal ion transport
FY150_15775	COG3273	potassium ion transport
FY150_15780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY150_15785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY150_15790	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY150_15800	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY150_15805	COG1121	(ABC) transporter
FY150_15810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY150_15815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY150_15825	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_15830	COG1414	Transcriptional regulator
FY150_15835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY150_15845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY150_15875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY150_15895	COG0395	ABC-type sugar transport system, permease component
FY150_15900	COG1175	transmembrane transport
FY150_15910	COG2390	Transcriptional regulator
FY150_15915	COG4172	Belongs to the ABC transporter superfamily
FY150_15920	COG1473	amidohydrolase
FY150_15925	COG4166	transmembrane transport
FY150_15930	COG0601	transmembrane transport
FY150_15935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_15945	COG0693	protein deglycase activity
FY150_15950	COG0154	amidase activity
FY150_15955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_15965	COG0747	negative chemotaxis
FY150_15970	COG0583	DNA-binding transcription factor activity
FY150_15980	COG0444	Belongs to the ABC transporter superfamily
FY150_15985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_15990	COG0601	transmembrane transport
FY150_15995	COG0747	negative chemotaxis
FY150_16010	COG1473	amidohydrolase
FY150_16015	COG2814	Major facilitator Superfamily
FY150_16020	COG0583	DNA-binding transcription factor activity
FY150_16025	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY150_16035	COG3842	ATPase activity
FY150_16055	COG1609	Transcriptional regulator
FY150_16060	COG0583	DNA-binding transcription factor activity
FY150_16065	COG1960	acyl-CoA dehydrogenase activity
FY150_16070	COG1629	transport
FY150_16070	COG4774	siderophore transport
FY150_16080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_16085	COG1120	ATPase activity
FY150_16090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_16095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_16105	COG2375	cellular response to nickel ion
FY150_16115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY150_16120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY150_16120	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY150_16130	COG1169	isochorismate synthase
FY150_16135	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY150_16140	COG1535	isochorismatase
FY150_16140	COG3433	isochorismatase activity
FY150_16145	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_16160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_16165	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY150_16175	COG0583	DNA-binding transcription factor activity
FY150_16180	COG3005	denitrification pathway
FY150_16190	COG0243	molybdopterin cofactor binding
FY150_16205	COG4459	periplasmic nitrate reductase
FY150_16215	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY150_16240	COG0826	peptidase U32
FY150_16250	COG3189	MarR family transcriptional regulator
FY150_16255	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY150_16285	COG3256	nitric oxide reductase
FY150_16290	COG0714	Associated with various cellular activities
FY150_16350	COG0673	inositol 2-dehydrogenase activity
FY150_16360	COG1609	Transcriptional regulator
FY150_16365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_16370	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_16375	COG1129	ABC transporter
FY150_16380	COG1879	ABC-type sugar transport system periplasmic component
FY150_16390	COG0583	DNA-binding transcription factor activity
FY150_16405	COG1609	Transcriptional regulator
FY150_16410	COG0673	inositol 2-dehydrogenase activity
FY150_16425	COG1175	transmembrane transport
FY150_16430	COG0395	ABC-type sugar transport system, permease component
FY150_16435	COG3842	ATPase activity
FY150_16470	COG3842	ATPase activity
FY150_16475	COG1178	ABC-type Fe3 transport system permease component
FY150_16500	COG0483	inositol monophosphate 1-phosphatase activity
FY150_16505	COG5001	Diguanylate cyclase
FY150_16505	COG3300	MHYT domain
FY150_16645	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_16655	COG1879	ABC-type sugar transport system periplasmic component
FY150_16665	COG1063	alcohol dehydrogenase
FY150_16675	COG1309	transcriptional regulator
FY150_16700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY150_16705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_16720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY150_16730	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY150_16730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY150_16740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_16760	COG1845	cytochrome c oxidase, subunit III
FY150_16765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY150_16770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY150_16780	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY150_16790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY150_16795	COG1177	transmembrane transport
FY150_16800	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY150_16805	COG3842	ATPase activity
FY150_16830	COG1335	isochorismatase
FY150_16845	COG0583	DNA-binding transcription factor activity
FY150_16850	COG2318	DinB family
FY150_16875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY150_16890	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY150_16895	COG1177	transmembrane transport
FY150_16905	COG3842	ATPase activity
FY150_16935	COG1177	transmembrane transport
FY150_16940	COG3842	ATPase activity
FY150_16965	COG0583	DNA-binding transcription factor activity
FY150_16985	COG0778	Nitroreductase
FY150_17005	COG0277	FAD linked oxidase domain protein
FY150_17015	COG0747	negative chemotaxis
FY150_17025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_17030	COG4172	Belongs to the ABC transporter superfamily
FY150_17040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_17060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_17065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY150_17085	COG1522	sequence-specific DNA binding
FY150_17090	COG2376	Dihydroxyacetone kinase
FY150_17110	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FY150_17125	COG0395	ABC-type sugar transport system, permease component
FY150_17160	COG1609	Transcriptional regulator
FY150_17165	COG1053	succinate dehydrogenase
FY150_17165	COG3976	FMN-binding domain protein
FY150_17175	COG1175	transmembrane transport
FY150_17180	COG0395	ABC-type sugar transport system, permease component
FY150_17185	COG3842	ATPase activity
FY150_17190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY150_17205	COG0300	oxidoreductase activity
FY150_17210	COG0500	methyltransferase
FY150_17245	COG0584	glycerophosphoryl diester phosphodiesterase
FY150_17250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_17320	COG0583	DNA-binding transcription factor activity
FY150_17385	COG2948	multi-organism process
FY150_17395	COG3701	Conjugal transfer protein
FY150_17400	COG3846	protein secretion by the type IV secretion system
FY150_17415	COG3451	type IV secretory pathway VirB4
FY150_17430	COG4962	Type ii secretion system protein e
FY150_17450	COG0741	lytic transglycosylase activity
FY150_17475	COG1192	Involved in chromosome partitioning
FY150_17505	COG1476	TRANSCRIPTIONal
FY150_17530	COG0629	single-stranded DNA binding
FY150_17655	COG0739	heme binding
FY150_17655	COG0741	lytic transglycosylase activity
FY150_17655	COG1196	nuclear chromosome segregation
FY150_17660	COG0542	response to heat
FY150_17670	COG2890	protein-(glutamine-N5) methyltransferase activity
FY150_17675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY150_17685	COG0527	aspartate kinase activity
FY150_17700	COG0019	diaminopimelate decarboxylase activity
FY150_17715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY150_17725	COG3920	Histidine kinase
FY150_17735	COG0784	Response regulator, receiver
FY150_17750	COG1522	sequence-specific DNA binding
FY150_17760	COG1116	anion transmembrane transporter activity
FY150_17765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_17770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY150_17775	COG1012	belongs to the aldehyde dehydrogenase family
FY150_17780	COG0583	DNA-binding transcription factor activity
FY150_17785	COG0435	Glutathione S-transferase
FY150_17795	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY150_17800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY150_17805	COG0189	ligase activity
FY150_17825	COG0693	protein deglycase activity
FY150_17845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_17850	COG1285	pathogenesis
FY150_17855	COG3685	Protein conserved in bacteria
FY150_17860	COG4993	Dehydrogenase
FY150_17875	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_17880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY150_17925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_17940	COG0246	Mannitol dehydrogenase
FY150_17945	COG4608	Belongs to the ABC transporter superfamily
FY150_17950	COG0444	Belongs to the ABC transporter superfamily
FY150_17955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_17960	COG0601	transmembrane transport
FY150_17965	COG0747	negative chemotaxis
FY150_17970	COG0006	proline dipeptidase activity
FY150_17975	COG4221	oxidoreductase activity
FY150_18005	COG0539	negative regulation of cytoplasmic translation
FY150_18010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY150_18040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY150_18045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY150_18075	COG1294	oxidase, subunit
FY150_18085	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY150_18090	COG4988	ABC transporter
FY150_18100	COG1063	alcohol dehydrogenase
FY150_18105	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_18110	COG2084	Dehydrogenase
FY150_18120	COG1522	sequence-specific DNA binding
FY150_18125	COG1794	racemase activity, acting on amino acids and derivatives
FY150_18135	COG0058	SHG alpha-glucan phosphorylase activity
FY150_18140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY150_18145	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY150_18150	COG0297	glycogen (starch) synthase activity
FY150_18155	COG0033	Phosphoglucomutase
FY150_18180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY150_18180	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY150_18195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_18200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY150_18220	COG1215	transferase activity, transferring glycosyl groups
FY150_18225	COG2327	Polysaccharide pyruvyl transferase
FY150_18230	COG0463	Glycosyl transferase, family 2
FY150_18235	COG2244	polysaccharide biosynthetic process
FY150_18240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY150_18245	COG2273	Hydrolase Family 16
FY150_18250	COG0438	transferase activity, transferring glycosyl groups
FY150_18255	COG1215	transferase activity, transferring glycosyl groups
FY150_18260	COG1215	transferase activity, transferring glycosyl groups
FY150_18265	COG1215	transferase activity, transferring glycosyl groups
FY150_18270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY150_18275	COG3206	protein involved in exopolysaccharide biosynthesis
FY150_18275	COG0489	protein tyrosine kinase activity
FY150_18285	COG4191	Histidine kinase
FY150_18285	COG0784	Response regulator, receiver
FY150_18295	COG4176	ABC-type proline glycine betaine transport system permease component
FY150_18300	COG4175	Glycine betaine
FY150_18300	COG3448	diguanylate cyclase activity
FY150_18305	COG2081	HI0933 family
FY150_18315	COG0564	pseudouridine synthase activity
FY150_18320	COG0500	methyltransferase
FY150_18330	COG2133	pyrroloquinoline quinone binding
FY150_18340	COG2197	response regulator
FY150_18345	COG4585	Histidine kinase
FY150_18350	COG1879	ABC-type sugar transport system periplasmic component
FY150_18355	COG1129	ABC transporter
FY150_18360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_18370	COG3386	PFAM SMP-30 Gluconolaconase
FY150_18375	COG2137	regulation of response to DNA damage stimulus
FY150_18380	COG3474	cytochrome
FY150_18390	COG1120	ATPase activity
FY150_18405	COG4774	siderophore transport
FY150_18410	COG0583	DNA-binding transcription factor activity
FY150_18420	COG2194	sulfuric ester hydrolase activity
FY150_18435	COG0477	Major facilitator Superfamily
FY150_18460	COG0673	inositol 2-dehydrogenase activity
FY150_18465	COG0697	spore germination
FY150_18475	COG0010	Belongs to the arginase family
FY150_18490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY150_18495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY150_18500	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY150_18510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY150_18560	COG0671	phosphoesterase, PA-phosphatase related
FY150_18565	COG0745	RESPONSE REGULATOR receiver
FY150_18570	COG5002	protein histidine kinase activity
FY150_18570	COG3850	Histidine kinase
FY150_18590	COG4774	siderophore transport
FY150_18610	COG0477	Major facilitator Superfamily
FY150_18615	COG0583	DNA-binding transcription factor activity
FY150_18625	COG1309	transcriptional regulator
FY150_18650	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY150_18665	COG0346	lactoylglutathione lyase activity
FY150_18670	COG0583	DNA-binding transcription factor activity
FY150_18700	COG1215	transferase activity, transferring glycosyl groups
FY150_18730	COG0431	NADPH-dependent FMN reductase
FY150_18735	COG0840	transmembrane signaling receptor activity
FY150_18755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_18770	COG2828	Protein conserved in bacteria
FY150_18775	COG0583	DNA-binding transcription factor activity
FY150_18780	COG1846	Transcriptional regulator
FY150_18810	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_18815	COG1309	transcriptional regulator
FY150_18820	COG1737	Transcriptional regulator
FY150_18840	COG4211	Belongs to the binding-protein-dependent transport system permease family
FY150_18850	COG1609	Transcriptional regulator
FY150_18870	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_18875	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_18880	COG1129	ABC transporter
FY150_18890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_18900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_18910	COG0747	negative chemotaxis
FY150_18915	COG0747	negative chemotaxis
FY150_18920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_18930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_18950	COG4191	Histidine kinase
FY150_18955	COG4566	intracellular signal transduction
FY150_19005	COG0402	S-adenosylhomocysteine deaminase activity
FY150_19010	COG1228	amidohydrolase
FY150_19015	COG2986	histidine ammonia-lyase
FY150_19025	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY150_19055	COG1192	Involved in chromosome partitioning
FY150_19060	COG1475	DNA binding
FY150_19065	COG1414	Transcriptional regulator
FY150_19085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY150_19090	COG4771	TonB-dependent receptor
FY150_19100	COG0366	Alpha amylase catalytic
FY150_19105	COG4770	biotin carboxylase activity
FY150_19110	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY150_19115	COG4336	lyase activity
FY150_19120	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY150_19125	COG1914	H( )-stimulated, divalent metal cation uptake system
FY150_19130	COG1802	Transcriptional regulator
FY150_19135	COG3707	response regulator
FY150_19140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY150_19145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY150_19150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_19155	COG1116	anion transmembrane transporter activity
FY150_19160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY150_19170	COG0243	molybdopterin cofactor binding
FY150_19175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY150_19175	COG1648	precorrin-2 dehydrogenase activity
FY150_19190	COG3842	ATPase activity
FY150_19205	COG0395	ABC-type sugar transport system, permease component
FY150_19220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY150_19235	COG0071	Belongs to the small heat shock protein (HSP20) family
FY150_19265	COG4166	transmembrane transport
FY150_19270	COG0601	transmembrane transport
FY150_19275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_19280	COG4172	Belongs to the ABC transporter superfamily
FY150_19295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_19300	COG0601	transmembrane transport
FY150_19315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_19330	COG1879	ABC-type sugar transport system periplasmic component
FY150_19335	COG1129	ABC transporter
FY150_19340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_19350	COG0667	Aldo Keto reductase
FY150_19355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY150_19360	COG1830	Aldolase
FY150_19365	COG1070	Carbohydrate kinase
FY150_19370	COG0840	transmembrane signaling receptor activity
FY150_19380	COG4221	oxidoreductase activity
FY150_19385	COG0436	Aminotransferase
FY150_19395	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY150_19405	COG3842	ATPase activity
FY150_19410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY150_19415	COG1984	allophanate hydrolase subunit 2
FY150_19420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY150_19430	COG0439	Biotin carboxylase
FY150_19435	COG0511	ligase activity, forming carbon-carbon bonds
FY150_19440	COG0697	spore germination
FY150_19445	COG0697	spore germination
FY150_19460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY150_19475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY150_19480	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_19485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY150_19490	COG4221	oxidoreductase activity
FY150_19495	COG0765	amino acid transport
FY150_19500	COG0765	amino acid transport
FY150_19510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_19515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY150_19520	COG1063	alcohol dehydrogenase
FY150_19530	COG0765	amino acid transport
FY150_19535	COG0765	amino acid transport
FY150_19575	COG1304	FMN binding
FY150_19600	COG3842	ATPase activity
FY150_19610	COG0395	ABC-type sugar transport system, permease component
FY150_19615	COG1175	transmembrane transport
FY150_19630	COG2186	Transcriptional regulator
FY150_19635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY150_19640	COG0488	(ABC) transporter
FY150_19655	COG2307	Protein conserved in bacteria
FY150_19655	COG2308	Evidence 4 Homologs of previously reported genes of
FY150_19695	COG1454	alcohol dehydrogenase
FY150_19700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY150_19710	COG0747	negative chemotaxis
FY150_19715	COG0601	transmembrane transport
FY150_19720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_19725	COG4172	Belongs to the ABC transporter superfamily
FY150_19730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_19770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY150_19775	COG1476	TRANSCRIPTIONal
FY150_19795	COG0732	type I restriction modification DNA specificity domain
FY150_19805	COG0582	viral genome integration into host DNA
FY150_19810	COG1082	Xylose isomerase domain protein TIM barrel
FY150_19815	COG1082	Xylose isomerase domain protein TIM barrel
FY150_19820	COG0673	inositol 2-dehydrogenase activity
FY150_19825	COG1082	Xylose isomerase domain protein TIM barrel
FY150_19845	COG1609	Transcriptional regulator
FY150_19855	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY150_19855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY150_19860	COG4311	Sarcosine oxidase, delta subunit
FY150_19865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_19870	COG4977	sequence-specific DNA binding
FY150_19880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY150_19885	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY150_19890	COG0069	glutamate synthase activity
FY150_19895	COG0174	glutamine synthetase
FY150_19910	COG2986	histidine ammonia-lyase
FY150_19915	COG4175	Glycine betaine
FY150_19915	COG0517	IMP dehydrogenase activity
FY150_19920	COG4176	ABC-type proline glycine betaine transport system permease component
FY150_19945	COG2267	carboxylic ester hydrolase activity
FY150_19955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_19960	COG1012	belongs to the aldehyde dehydrogenase family
FY150_19980	COG1177	transmembrane transport
FY150_20015	COG2186	Transcriptional regulator
FY150_20020	COG1027	Aspartate ammonia-lyase
FY150_20030	COG0252	asparaginase activity
FY150_20040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY150_20045	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY150_20050	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY150_20055	COG2205	protein histidine kinase activity
FY150_20070	COG0070	glutamate synthase
FY150_20070	COG0069	glutamate synthase activity
FY150_20070	COG0067	glutamate synthase
FY150_20085	COG2205	protein histidine kinase activity
FY150_20100	COG2951	lytic endotransglycosylase activity
FY150_20105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY150_20130	COG0330	HflC and HflK could
FY150_20135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY150_20140	COG0737	Belongs to the 5'-nucleotidase family
FY150_20150	COG5310	Homospermidine synthase
FY150_20160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY150_20165	COG1164	Oligoendopeptidase f
FY150_20170	COG2204	response regulator
FY150_20175	COG3108	Peptidase M15
FY150_20180	COG0469	pyruvate kinase activity
FY150_20200	COG3750	Belongs to the UPF0335 family
FY150_20205	COG0457	Tetratricopeptide repeat
FY150_20210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY150_20215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY150_20220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY150_20250	COG0483	inositol monophosphate 1-phosphatase activity
FY150_20270	COG1132	(ABC) transporter
FY150_20275	COG0254	rRNA binding
FY150_20315	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_20330	COG1414	Transcriptional regulator
FY150_20340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_20345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY150_20345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_20350	COG3588	fructose-bisphosphate aldolase
FY150_20355	COG0126	phosphoglycerate kinase activity
FY150_20395	COG1253	flavin adenine dinucleotide binding
FY150_20405	COG1692	metallophosphoesterase
FY150_20420	COG0217	transcriptional regulatory protein
FY150_20425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_20430	COG0840	transmembrane signaling receptor activity
FY150_20435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY150_20440	COG0632	four-way junction helicase activity
FY150_20455	COG2255	four-way junction helicase activity
FY150_20470	COG0494	nUDIX hydrolase
FY150_20480	COG0824	Thioesterase
FY150_20500	COG0823	Involved in the tonB-independent uptake of proteins
FY150_20505	COG2885	chlorophyll binding
FY150_20515	COG0037	tRNA processing
FY150_20520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY150_20525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY150_20540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY150_20555	COG0482	sulfurtransferase activity
FY150_20585	COG2835	tetraacyldisaccharide 4'-kinase activity
FY150_20590	COG2373	Large extracellular alpha-helical protein
FY150_20595	COG4953	penicillin-binding protein 1C
FY150_20605	COG1473	amidohydrolase
FY150_20610	COG1686	Belongs to the peptidase S11 family
FY150_20615	COG0523	cobalamin synthesis protein
FY150_20620	COG0425	Belongs to the sulfur carrier protein TusA family
FY150_20620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY150_20625	COG3034	peptidoglycan biosynthetic process
FY150_20630	COG0825	malonyl-CoA metabolic process
FY150_20635	COG4974	Belongs to the 'phage' integrase family
FY150_20645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY150_20650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY150_20685	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY150_20690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY150_20705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY150_20710	COG2226	methyltransferase
FY150_20715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY150_20720	COG0287	Prephenate dehydrogenase
FY150_20730	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY150_20750	COG2884	Cell division ATP-binding protein ftsE
FY150_20785	COG0165	Argininosuccinate lyase
FY150_20790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY150_20795	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY150_20805	COG2086	electron transfer activity
FY150_20815	COG2096	Adenosyltransferase
FY150_20825	COG0300	oxidoreductase activity
FY150_20835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY150_20845	COG1396	sequence-specific DNA binding
FY150_20845	COG3800	Transcriptional regulator
FY150_20850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY150_20855	COG0625	glutathione transferase activity
FY150_20865	COG4770	biotin carboxylase activity
FY150_20870	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY150_20870	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY150_20875	COG0346	lactoylglutathione lyase activity
FY150_20890	COG4213	ABC transporter substrate-binding protein
FY150_20895	COG4214	carbohydrate transport
FY150_20900	COG1129	ABC transporter
FY150_20905	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY150_20915	COG1396	sequence-specific DNA binding
FY150_20960	COG2273	Hydrolase Family 16
FY150_20960	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY150_20965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY150_20980	COG0438	transferase activity, transferring glycosyl groups
FY150_20985	COG0438	transferase activity, transferring glycosyl groups
FY150_20990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY150_21010	COG3206	protein involved in exopolysaccharide biosynthesis
FY150_21010	COG0489	protein tyrosine kinase activity
FY150_21020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY150_21035	COG2244	polysaccharide biosynthetic process
FY150_21080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY150_21100	COG0840	transmembrane signaling receptor activity
FY150_21100	COG2972	Histidine kinase
FY150_21110	COG0483	inositol monophosphate 1-phosphatase activity
FY150_21120	COG3842	ATPase activity
FY150_21130	COG1175	transmembrane transport
FY150_21140	COG1940	carbohydrate kinase activity
FY150_21140	COG1846	Transcriptional regulator
FY150_21165	COG1289	transmembrane transporter activity
FY150_21185	COG2272	Belongs to the type-B carboxylesterase lipase family
FY150_21195	COG2272	Belongs to the type-B carboxylesterase lipase family
FY150_21240	COG1629	transport
FY150_21240	COG4774	siderophore transport
FY150_21255	COG3181	Tripartite tricarboxylate transporter family receptor
FY150_21270	COG0583	DNA-binding transcription factor activity
FY150_21280	COG2159	amidohydrolase
FY150_21285	COG0583	DNA-binding transcription factor activity
FY150_21290	COG1301	dicarboxylic acid transport
FY150_21295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY150_21310	COG0583	DNA-binding transcription factor activity
FY150_21345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY150_21360	COG2843	Capsule synthesis protein
FY150_21365	COG0444	Belongs to the ABC transporter superfamily
FY150_21380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_21390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY150_21425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY150_21450	COG0745	RESPONSE REGULATOR receiver
FY150_21460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_21505	COG0625	glutathione transferase activity
FY150_21515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY150_21525	COG4689	acetoacetate decarboxylase
FY150_21535	COG1012	belongs to the aldehyde dehydrogenase family
FY150_21540	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FY150_21560	COG0840	transmembrane signaling receptor activity
FY150_21625	COG1175	transmembrane transport
FY150_21630	COG0395	ABC-type sugar transport system, permease component
FY150_21670	COG0697	spore germination
FY150_21675	COG0653	protein targeting
FY150_21680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY150_21685	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY150_21695	COG0494	nUDIX hydrolase
FY150_21710	COG2226	methyltransferase
FY150_21715	COG1040	competence protein
FY150_21725	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY150_21735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY150_21750	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY150_21765	COG4208	sulfate ABC transporter
FY150_21770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY150_21775	COG4335	DNA alkylation repair
FY150_21790	COG5001	Diguanylate cyclase
FY150_21795	COG2264	protein methyltransferase activity
FY150_21810	COG3254	rhamnose metabolic process
FY150_21815	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_21820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_21825	COG1129	ABC transporter
FY150_21835	COG1349	DNA-binding transcription factor activity
FY150_21840	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_21840	COG3347	Dehydrogenase
FY150_21845	COG4952	isomerase
FY150_21850	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY150_21855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY150_21860	COG1024	Enoyl-CoA hydratase
FY150_21875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY150_21880	COG1960	acyl-CoA dehydrogenase activity
FY150_21890	COG0183	Belongs to the thiolase family
FY150_21895	COG1960	acyl-CoA dehydrogenase activity
FY150_21905	COG0022	dehydrogenase e1 component
FY150_21915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY150_21920	COG2391	methyltransferase activity
FY150_21930	COG0640	Transcriptional regulator
FY150_21935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY150_21935	COG3453	Protein conserved in bacteria
FY150_21960	COG2186	Transcriptional regulator
FY150_21970	COG0601	transmembrane transport
FY150_21980	COG0444	Belongs to the ABC transporter superfamily
FY150_21985	COG4608	Belongs to the ABC transporter superfamily
FY150_22005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22030	COG1473	amidohydrolase
FY150_22035	COG0747	negative chemotaxis
FY150_22045	COG4166	transmembrane transport
FY150_22050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22055	COG0583	DNA-binding transcription factor activity
FY150_22065	COG0667	Aldo Keto reductase
FY150_22075	COG0444	Belongs to the ABC transporter superfamily
FY150_22100	COG1960	acyl-CoA dehydrogenase activity
FY150_22130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY150_22145	COG1959	2 iron, 2 sulfur cluster binding
FY150_22150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22160	COG1473	amidohydrolase
FY150_22170	COG1126	abc transporter atp-binding protein
FY150_22175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_22185	COG0583	DNA-binding transcription factor activity
FY150_22200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_22210	COG1522	sequence-specific DNA binding
FY150_22215	COG4172	Belongs to the ABC transporter superfamily
FY150_22220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_22260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_22265	COG1012	belongs to the aldehyde dehydrogenase family
FY150_22270	COG0473	3-isopropylmalate dehydrogenase activity
FY150_22275	COG1012	belongs to the aldehyde dehydrogenase family
FY150_22300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY150_22320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_22325	COG1120	ATPase activity
FY150_22335	COG2226	methyltransferase
FY150_22350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY150_22355	COG1120	ATPase activity
FY150_22360	COG1595	DNA-templated transcription, initiation
FY150_22380	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY150_22385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_22405	COG0673	inositol 2-dehydrogenase activity
FY150_22410	COG0673	inositol 2-dehydrogenase activity
FY150_22420	COG1175	transmembrane transport
FY150_22425	COG0395	ABC-type sugar transport system, permease component
FY150_22440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY150_22445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY150_22450	COG2197	response regulator
FY150_22455	COG0601	transmembrane transport
FY150_22460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_22480	COG0747	negative chemotaxis
FY150_22495	COG1446	asparaginase
FY150_22500	COG0583	DNA-binding transcription factor activity
FY150_22505	COG0601	transmembrane transport
FY150_22510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_22530	COG1473	amidohydrolase
FY150_22545	COG1129	ABC transporter
FY150_22550	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_22555	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY150_22560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY150_22570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY150_22585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_22595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_22600	COG2079	MmgE PrpD family protein
FY150_22605	COG1126	abc transporter atp-binding protein
FY150_22610	COG0765	amino acid transport
FY150_22625	COG0281	malic enzyme
FY150_22625	COG0280	phosphate acetyltransferase
FY150_22645	COG1175	transmembrane transport
FY150_22650	COG0395	ABC-type sugar transport system, permease component
FY150_22665	COG0673	inositol 2-dehydrogenase activity
FY150_22670	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY150_22675	COG0720	synthase
FY150_22680	COG0602	queuosine metabolic process
FY150_22685	COG0673	inositol 2-dehydrogenase activity
FY150_22710	COG1653	transport
FY150_22715	COG1609	Transcriptional regulator
FY150_22730	COG2094	Belongs to the DNA glycosylase MPG family
FY150_22740	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_22750	COG1376	ErfK ybiS ycfS ynhG family protein
FY150_22755	COG0840	transmembrane signaling receptor activity
FY150_22760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY150_22770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY150_22775	COG1596	polysaccharide export
FY150_22780	COG3307	-O-antigen
FY150_22810	COG2197	response regulator
FY150_22820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY150_22845	COG2942	2-epimerase
FY150_22855	COG1215	transferase activity, transferring glycosyl groups
FY150_22875	COG1473	amidohydrolase
FY150_22885	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_22890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY150_22900	COG1301	dicarboxylic acid transport
FY150_22905	COG4191	Histidine kinase
FY150_22910	COG2204	response regulator
FY150_22925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY150_22930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY150_22935	COG1522	sequence-specific DNA binding
FY150_22940	COG0351	phosphomethylpyrimidine kinase
FY150_22945	COG0352	thiamine-phosphate diphosphorylase activity
FY150_22950	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY150_22955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY150_22960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_22970	COG1501	Belongs to the glycosyl hydrolase 31 family
FY150_22975	COG0395	ABC-type sugar transport system, permease component
FY150_22980	COG1175	transmembrane transport
FY150_22985	COG1653	transport
FY150_22990	COG3842	ATPase activity
FY150_23005	COG4989	oxidoreductase activity
FY150_23030	COG0438	transferase activity, transferring glycosyl groups
FY150_23035	COG0747	negative chemotaxis
FY150_23040	COG0601	transmembrane transport
FY150_23050	COG3964	amidohydrolase
FY150_23065	COG1921	L-seryl-tRNASec selenium transferase activity
FY150_23075	COG0625	glutathione transferase activity
FY150_23090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY150_23095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_23095	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY150_23100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_23120	COG1312	Catalyzes the dehydration of D-mannonate
FY150_23125	COG1063	alcohol dehydrogenase
FY150_23130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_23140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_23145	COG2186	Transcriptional regulator
FY150_23150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY150_23155	COG0850	regulation of cytokinetic process
FY150_23160	COG2894	cell division
FY150_23165	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY150_23180	COG5001	Diguanylate cyclase
FY150_23195	COG3718	enzyme involved in inositol metabolism
FY150_23205	COG3962	Belongs to the TPP enzyme family
FY150_23210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_23225	COG0411	ABC transporter
FY150_23230	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY150_23240	COG0683	leucine binding
FY150_23255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_23265	COG0747	negative chemotaxis
FY150_23270	COG4172	Belongs to the ABC transporter superfamily
FY150_23290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY150_23295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY150_23300	COG1126	abc transporter atp-binding protein
FY150_23305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_23310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY150_23315	COG0765	amino acid transport
FY150_23320	COG0765	amino acid transport
FY150_23325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY150_23330	COG3485	protocatechuate 3,4-dioxygenase
FY150_23335	COG3485	protocatechuate 3,4-dioxygenase
FY150_23340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY150_23350	COG0583	DNA-binding transcription factor activity
FY150_23365	COG1414	Transcriptional regulator
FY150_23375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY150_23380	COG0183	Belongs to the thiolase family
FY150_23385	COG1609	Transcriptional regulator
FY150_23400	COG1082	Xylose isomerase domain protein TIM barrel
FY150_23405	COG0673	inositol 2-dehydrogenase activity
FY150_23415	COG1609	Transcriptional regulator
FY150_23430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY150_23440	COG0673	inositol 2-dehydrogenase activity
FY150_23450	COG1653	transport
FY150_23455	COG1175	transmembrane transport
FY150_23460	COG0395	ABC-type sugar transport system, permease component
FY150_23465	COG3842	ATPase activity
FY150_23475	COG0673	inositol 2-dehydrogenase activity
FY150_23500	COG0587	DNA-directed DNA polymerase activity
FY150_23515	COG2186	Transcriptional regulator
FY150_23520	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_23525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_23530	COG1129	ABC transporter
FY150_23535	COG1879	ABC-type sugar transport system periplasmic component
FY150_23540	COG0129	dihydroxy-acid dehydratase activity
FY150_23550	COG0346	lactoylglutathione lyase activity
FY150_23565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY150_23570	COG4608	Belongs to the ABC transporter superfamily
FY150_23580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_23585	COG0601	transmembrane transport
FY150_23590	COG0747	negative chemotaxis
FY150_23600	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY150_23615	COG3257	ureidoglycine aminohydrolase activity
FY150_23625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_23630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY150_23640	COG1129	ABC transporter
FY150_23645	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_23650	COG1879	ABC-type sugar transport system periplasmic component
FY150_23655	COG0583	DNA-binding transcription factor activity
FY150_23680	COG3047	cAMP biosynthetic process
FY150_23690	COG3842	ATPase activity
FY150_23695	COG0395	ABC-type sugar transport system, permease component
FY150_23700	COG1175	transmembrane transport
FY150_23705	COG1653	transport
FY150_23710	COG0523	cobalamin synthesis protein
FY150_23725	COG0523	cobalamin synthesis protein
FY150_23730	COG1121	(ABC) transporter
FY150_23740	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY150_23755	COG0626	cystathionine gamma-synthase activity
FY150_23760	COG2182	Extracellular solute-binding protein
FY150_23765	COG1175	transmembrane transport
FY150_23770	COG0395	ABC-type sugar transport system, permease component
FY150_23785	COG0395	ABC-type sugar transport system, permease component
FY150_23790	COG1175	transmembrane transport
FY150_23795	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY150_23800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY150_23810	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_23815	COG1063	alcohol dehydrogenase
FY150_23820	COG1609	Transcriptional regulator
FY150_23835	COG2084	Dehydrogenase
FY150_23840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_23850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_23855	COG0583	DNA-binding transcription factor activity
FY150_23860	COG2223	nitrite transmembrane transporter activity
FY150_23865	COG4977	sequence-specific DNA binding
FY150_23915	COG2186	Transcriptional regulator
FY150_23920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY150_23925	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY150_23930	COG1028	Short-chain dehydrogenase reductase Sdr
FY150_23935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_23940	COG4948	Mandelate Racemase Muconate Lactonizing
FY150_23945	COG3618	amidohydrolase
FY150_23950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_23970	COG1175	transmembrane transport
FY150_23975	COG0395	ABC-type sugar transport system, permease component
FY150_23980	COG3842	ATPase activity
FY150_23995	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY150_24020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_24025	COG0577	efflux transmembrane transporter activity
FY150_24025	COG1136	(ABC) transporter
FY150_24030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY150_24050	COG1278	Cold shock
FY150_24055	COG0673	inositol 2-dehydrogenase activity
FY150_24070	COG0673	inositol 2-dehydrogenase activity
FY150_24075	COG1309	transcriptional regulator
FY150_24080	COG1653	transport
FY150_24085	COG1175	transmembrane transport
FY150_24090	COG0395	ABC-type sugar transport system, permease component
FY150_24095	COG3842	ATPase activity
FY150_24110	COG1082	Xylose isomerase domain protein TIM barrel
FY150_24125	COG1609	Transcriptional regulator
FY150_24155	COG1175	transmembrane transport
FY150_24160	COG0395	ABC-type sugar transport system, permease component
FY150_24165	COG1116	anion transmembrane transporter activity
FY150_24170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY150_24175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY150_24190	COG2072	flavoprotein involved in K transport
FY150_24210	COG3842	ATPase activity
FY150_24215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY150_24235	COG3842	ATPase activity
FY150_24240	COG0395	ABC-type sugar transport system, permease component
FY150_24250	COG1653	transport
FY150_24290	COG3842	ATPase activity
FY150_24300	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY150_24305	COG0395	ABC-type sugar transport system, permease component
FY150_24355	COG2233	PERMEase
FY150_24360	COG0702	epimerase
FY150_24380	COG4172	Belongs to the ABC transporter superfamily
FY150_24400	COG0747	negative chemotaxis
FY150_24405	COG0601	transmembrane transport
FY150_24410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY150_24435	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FY150_24440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY150_24455	COG1609	Transcriptional regulator
FY150_24460	COG1696	Membrane protein involved in D-alanine export
FY150_24520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY150_24530	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY150_24535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY150_24545	COG4106	trans-aconitate 2-methyltransferase activity
FY150_24560	COG0270	DNA (cytosine-5-)-methyltransferase activity
FY150_24565	COG0110	maltose O-acetyltransferase activity
FY150_24585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY150_24590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY150_24595	COG2200	EAL domain
FY150_24600	COG2204	response regulator
FY150_24635	COG4957	zinc ion binding
FY150_24645	COG2860	membrane
FY150_24650	COG3422	double-strand break repair
FY150_24700	COG3706	GGDEF domain
FY150_24710	COG0475	glutathione-regulated potassium exporter activity
FY150_24710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY150_24730	COG0583	DNA-binding transcription factor activity
FY150_24740	COG0494	nUDIX hydrolase
FY150_24780	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY150_24785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY150_24790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY150_24805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY150_24810	COG2186	Transcriptional regulator
FY150_24815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY150_24865	COG3505	Type IV secretory pathway VirD4
FY150_24900	COG5489	Protein of unknown function (DUF736)
FY150_24950	COG2824	Alkylphosphonate utilization operon protein PhnA
FY150_24970	COG1475	DNA binding
FY150_25010	COG4957	zinc ion binding
FY150_25035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY150_25045	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY150_25075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY150_25090	COG0640	Transcriptional regulator
FY150_25095	COG1475	DNA binding
FY150_25100	COG1192	Involved in chromosome partitioning
FY150_25120	COG3838	Conjugal transfer protein Trbc
FY150_25125	COG3702	type iv secretory pathway
FY150_25130	COG3451	type IV secretory pathway VirB4
FY150_25145	COG3704	protein secretion by the type IV secretion system
FY150_25155	COG3736	Type IV secretory pathway, component VirB8
FY150_25160	COG3504	Conjugal transfer protein
FY150_25165	COG2948	multi-organism process
FY150_25170	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY150_25180	COG4977	sequence-specific DNA binding
FY150_25185	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY150_25195	COG2200	EAL domain
FY150_25200	COG2204	response regulator
FY150_25225	COG2274	protein secretion by the type I secretion system
FY150_25235	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY150_25235	COG2918	glutathione biosynthetic process