locus-tag	class	description
FY152_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY152_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY152_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY152_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY152_00025	COG1420	regulation of RNA biosynthetic process
FY152_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY152_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY152_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY152_00050	COG1137	ATPase activity
FY152_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY152_00065	COG0616	signal peptide processing
FY152_00070	COG0776	regulation of translation
FY152_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY152_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY152_00095	COG4999	Histidine kinase
FY152_00095	COG3850	Histidine kinase
FY152_00095	COG2205	protein histidine kinase activity
FY152_00095	COG3437	response regulator, receiver
FY152_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY152_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY152_00115	COG0728	peptidoglycan biosynthetic process
FY152_00125	COG0180	Tryptophanyl-tRNA synthetase
FY152_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY152_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY152_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY152_00165	COG1702	phosphate starvation-inducible protein PhoH
FY152_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY152_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY152_00185	COG1396	sequence-specific DNA binding
FY152_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY152_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY152_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_00210	COG0242	peptide deformylase activity
FY152_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY152_00220	COG0101	tRNA pseudouridine synthase activity
FY152_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY152_00235	COG2171	N-acyltransferase activity
FY152_00245	COG0840	transmembrane signaling receptor activity
FY152_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY152_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY152_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY152_00295	COG0706	membrane insertase activity
FY152_00300	COG0594	ribonuclease P activity
FY152_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY152_00310	COG0840	transmembrane signaling receptor activity
FY152_00325	COG2226	methyltransferase
FY152_00330	COG3842	ATPase activity
FY152_00335	COG1175	transmembrane transport
FY152_00340	COG0395	ABC-type sugar transport system, permease component
FY152_00355	COG0427	acetyl-CoA hydrolase
FY152_00365	COG3938	Belongs to the proline racemase family
FY152_00370	COG0418	dihydroorotase activity
FY152_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY152_00395	COG0166	Belongs to the GPI family
FY152_00400	COG0318	PFAM AMP-dependent synthetase and ligase
FY152_00405	COG3842	ATPase activity
FY152_00410	COG1840	ABC-type Fe3 transport system, periplasmic component
FY152_00415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY152_00420	COG4774	siderophore transport
FY152_00460	COG2326	polyphosphate kinase activity
FY152_00465	COG5002	protein histidine kinase activity
FY152_00470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY152_00475	COG0573	inorganic phosphate transmembrane transporter activity
FY152_00485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY152_00490	COG0704	Plays a role in the regulation of phosphate uptake
FY152_00495	COG0745	RESPONSE REGULATOR receiver
FY152_00505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY152_00510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY152_00520	COG2967	ApaG domain
FY152_00535	COG0717	Belongs to the dCTP deaminase family
FY152_00545	COG0582	viral genome integration into host DNA
FY152_00555	COG0270	DNA (cytosine-5-)-methyltransferase activity
FY152_00560	COG0270	DNA (cytosine-5-)-methyltransferase activity
FY152_00675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY152_00725	COG0167	dihydroorotate dehydrogenase activity
FY152_00760	COG1959	2 iron, 2 sulfur cluster binding
FY152_00765	COG1201	RNA secondary structure unwinding
FY152_00795	COG1960	acyl-CoA dehydrogenase activity
FY152_00800	COG0183	Belongs to the thiolase family
FY152_00805	COG1024	Enoyl-CoA hydratase
FY152_00805	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY152_00830	COG1320	monovalent cation:proton antiporter activity
FY152_00835	COG2212	antiporter activity
FY152_00840	COG1863	multisubunit Na H antiporter MnhE subunit
FY152_00845	COG0651	ATP synthesis coupled electron transport
FY152_00850	COG1006	Multisubunit Na H antiporter MnhC subunit
FY152_00855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY152_00855	COG2111	Na H antiporter
FY152_00865	COG0840	transmembrane signaling receptor activity
FY152_00875	COG0745	RESPONSE REGULATOR receiver
FY152_00880	COG0643	Histidine kinase
FY152_00880	COG2198	Histidine kinase
FY152_00885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY152_00890	COG2201	protein-glutamate methylesterase activity
FY152_00895	COG0745	RESPONSE REGULATOR receiver
FY152_00900	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY152_00910	COG1766	The M ring may be actively involved in energy transduction
FY152_00915	COG2771	luxR family
FY152_00925	COG0840	transmembrane signaling receptor activity
FY152_00925	COG2972	Histidine kinase
FY152_00930	COG0784	Response regulator, receiver
FY152_00930	COG2198	Histidine kinase
FY152_00930	COG2205	protein histidine kinase activity
FY152_00935	COG1970	mechanosensitive ion channel activity
FY152_00940	COG0436	Aminotransferase
FY152_00955	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY152_00960	COG0424	maF-like protein
FY152_00965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY152_00975	COG5328	Belongs to the UPF0262 family
FY152_00980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY152_00990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY152_01010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY152_01025	COG1338	Plays a role in the flagellum-specific transport system
FY152_01035	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY152_01045	COG1706	bacterial-type flagellum-dependent cell motility
FY152_01050	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY152_01055	COG4786	Flagellar basal body rod
FY152_01060	COG1677	Flagellar hook-basal body complex protein FliE
FY152_01065	COG1558	bacterial-type flagellum-dependent cell motility
FY152_01070	COG1815	bacterial-type flagellum-dependent cell motility
FY152_01080	COG1157	protein secretion by the type III secretion system
FY152_01085	COG4786	Flagellar basal body rod
FY152_01095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY152_01100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY152_01105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY152_01110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY152_01115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY152_01135	COG1360	Flagellar Motor Protein
FY152_01160	COG1749	Flagellar hook protein flgE
FY152_01180	COG5443	negative regulation of bacterial-type flagellum assembly
FY152_01185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY152_01195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY152_01235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY152_01240	COG1609	Transcriptional regulator
FY152_01245	COG1653	transport
FY152_01250	COG1175	transmembrane transport
FY152_01255	COG0395	ABC-type sugar transport system, permease component
FY152_01260	COG0366	Alpha amylase catalytic
FY152_01265	COG3842	ATPase activity
FY152_01280	COG0129	dihydroxy-acid dehydratase activity
FY152_01285	COG0363	glucosamine-6-phosphate deaminase activity
FY152_01290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY152_01295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_01305	COG2081	HI0933 family
FY152_01325	COG2224	Isocitrate lyase
FY152_01340	COG3842	ATPase activity
FY152_01345	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_01350	COG1177	transmembrane transport
FY152_01360	COG2205	protein histidine kinase activity
FY152_01370	COG0248	Ppx GppA phosphatase
FY152_01375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY152_01380	COG0477	Major facilitator Superfamily
FY152_01410	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY152_01415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY152_01425	COG0142	geranyltranstransferase activity
FY152_01460	COG0752	glycyl-tRNA synthetase alpha subunit
FY152_01470	COG1704	LemA family
FY152_01475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY152_01485	COG0751	glycine-tRNA ligase activity
FY152_01490	COG1683	Conserved Protein
FY152_01495	COG0840	transmembrane signaling receptor activity
FY152_01505	COG0151	Belongs to the GarS family
FY152_01510	COG2183	response to ionizing radiation
FY152_01515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY152_01540	COG0583	DNA-binding transcription factor activity
FY152_01570	COG0306	phosphate transporter
FY152_01580	COG0561	phosphatase activity
FY152_01585	COG0438	transferase activity, transferring glycosyl groups
FY152_01590	COG2186	Transcriptional regulator
FY152_01600	COG0583	DNA-binding transcription factor activity
FY152_01605	COG0277	FAD linked oxidase domain protein
FY152_01610	COG0277	FAD linked oxidase domain protein
FY152_01615	COG0247	lactate metabolic process
FY152_01625	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_01630	COG2818	Glycosylase
FY152_01640	COG2855	membrane
FY152_01645	COG0583	DNA-binding transcription factor activity
FY152_01675	COG0124	histidyl-tRNA synthetase
FY152_01685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY152_01690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY152_01695	COG2259	Doxx family
FY152_01705	COG0459	protein refolding
FY152_01710	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY152_01720	COG0196	riboflavin kinase activity
FY152_01725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY152_01735	COG0590	tRNA wobble adenosine to inosine editing
FY152_01740	COG1187	pseudouridine synthase activity
FY152_01745	COG0742	ribosomal rna small subunit methyltransferase
FY152_01750	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY152_01755	COG0475	glutathione-regulated potassium exporter activity
FY152_01755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY152_01760	COG0312	modulator of DNA gyrase
FY152_01765	COG0483	inositol monophosphate 1-phosphatase activity
FY152_01775	COG1519	Transferase
FY152_01785	COG1663	tetraacyldisaccharide 4'-kinase activity
FY152_01795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY152_01805	COG3300	MHYT domain
FY152_01805	COG5001	Diguanylate cyclase
FY152_01810	COG3386	PFAM SMP-30 Gluconolaconase
FY152_01815	COG0800	Aldolase
FY152_01820	COG3734	2-keto-3-deoxy-galactonokinase
FY152_01825	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_01830	COG1414	Transcriptional regulator
FY152_01835	COG2197	response regulator
FY152_01840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY152_01850	COG0598	Magnesium transport protein CorA
FY152_01855	COG3158	transport of potassium into the cell
FY152_01870	COG0356	it plays a direct role in the translocation of protons across the membrane
FY152_01880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY152_01885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY152_01890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY152_01895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY152_01920	COG0009	L-threonylcarbamoyladenylate synthase
FY152_01930	COG4638	Rieske (2fe-2S)
FY152_01955	COG1960	acyl-CoA dehydrogenase activity
FY152_01970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY152_01975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY152_01980	COG0840	transmembrane signaling receptor activity
FY152_02010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY152_02015	COG1741	Belongs to the pirin family
FY152_02020	COG1722	exodeoxyribonuclease VII activity
FY152_02025	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY152_02030	COG1268	BioY protein
FY152_02035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY152_02040	COG1122	ATPase activity
FY152_02045	COG3214	Protein conserved in bacteria
FY152_02050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY152_02050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY152_02055	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY152_02070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY152_02075	COG0484	heat shock protein binding
FY152_02085	COG0259	pyridoxamine-phosphate oxidase activity
FY152_02105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY152_02115	COG0312	modulator of DNA gyrase
FY152_02130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY152_02135	COG0109	protoheme IX farnesyltransferase activity
FY152_02140	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY152_02155	COG3346	SURF1 family
FY152_02160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY152_02165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY152_02170	COG0328	RNA-DNA hybrid ribonuclease activity
FY152_02180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY152_02180	COG0678	peroxiredoxin activity
FY152_02190	COG1678	Uncharacterized ACR, COG1678
FY152_02195	COG3237	CsbD-like
FY152_02205	COG5001	Diguanylate cyclase
FY152_02205	COG3300	MHYT domain
FY152_02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY152_02215	COG0612	Peptidase, M16
FY152_02230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY152_02235	COG1802	Transcriptional regulator
FY152_02250	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY152_02260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY152_02270	COG1194	a g-specific adenine glycosylase
FY152_02285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY152_02290	COG1196	nuclear chromosome segregation
FY152_02295	COG2514	catechol 2,3-dioxygenase activity
FY152_02300	COG0574	Belongs to the PEP-utilizing enzyme family
FY152_02300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY152_02310	COG1823	symporter activity
FY152_02340	COG0579	oxidoreductase
FY152_02365	COG2895	sulfate adenylyltransferase (ATP) activity
FY152_02370	COG0175	sulfate reduction
FY152_02375	COG0175	sulfate reduction
FY152_02380	COG1959	2 iron, 2 sulfur cluster binding
FY152_02385	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY152_02390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY152_02395	COG4208	sulfate ABC transporter
FY152_02400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY152_02410	COG2199	diguanylate cyclase activity
FY152_02410	COG2200	EAL domain
FY152_02410	COG2203	Gaf domain
FY152_02425	COG1309	transcriptional regulator
FY152_02430	COG1012	belongs to the aldehyde dehydrogenase family
FY152_02435	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY152_02480	COG0477	Major facilitator Superfamily
FY152_02490	COG1793	dna ligase
FY152_02505	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_02510	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_02515	COG1846	Transcriptional regulator
FY152_02520	COG1764	response to oxidative stress
FY152_02565	COG0488	(ABC) transporter
FY152_02575	COG0433	COG0433 Predicted ATPase
FY152_02585	COG1733	regulation of RNA biosynthetic process
FY152_02590	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY152_02600	COG1280	lysine exporter protein (LysE YggA)
FY152_02605	COG0656	L-ascorbic acid biosynthetic process
FY152_02610	COG3781	membrane
FY152_02615	COG2378	regulation of single-species biofilm formation
FY152_02625	COG4106	trans-aconitate 2-methyltransferase activity
FY152_02630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY152_02635	COG0840	transmembrane signaling receptor activity
FY152_02640	COG0583	DNA-binding transcription factor activity
FY152_02655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY152_02675	COG3909	cytochrome
FY152_02680	COG2010	Cytochrome c
FY152_02715	COG0789	Transcriptional regulator
FY152_02740	COG0517	IMP dehydrogenase activity
FY152_02740	COG4175	Glycine betaine
FY152_02745	COG4176	ABC-type proline glycine betaine transport system permease component
FY152_02770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_02780	COG2169	Transcriptional regulator
FY152_02780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY152_02790	COG2514	catechol 2,3-dioxygenase activity
FY152_02800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FY152_02805	COG1272	protein, Hemolysin III
FY152_02815	COG1280	lysine exporter protein (LysE YggA)
FY152_02820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY152_02825	COG2111	Na H antiporter
FY152_02825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY152_02830	COG2111	Na H antiporter
FY152_02835	COG1006	Multisubunit Na H antiporter MnhC subunit
FY152_02840	COG0651	ATP synthesis coupled electron transport
FY152_02845	COG1863	multisubunit Na H antiporter MnhE subunit
FY152_02850	COG2212	antiporter activity
FY152_02855	COG1320	monovalent cation:proton antiporter activity
FY152_02860	COG4957	zinc ion binding
FY152_02875	COG2166	iron-sulfur cluster assembly
FY152_02885	COG2205	protein histidine kinase activity
FY152_02930	COG0583	DNA-binding transcription factor activity
FY152_02940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY152_02945	COG2983	Belongs to the UPF0260 family
FY152_02965	COG2217	Heavy metal translocating P-type atpase
FY152_02995	COG0477	Major facilitator Superfamily
FY152_03000	COG1621	beta-fructofuranosidase activity
FY152_03005	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY152_03050	COG4695	Portal protein
FY152_03155	COG4235	cytochrome complex assembly
FY152_03160	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY152_03165	COG1138	Cytochrome C-type biogenesis protein
FY152_03170	COG3088	subunit of a heme lyase
FY152_03175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY152_03190	COG3011	Protein conserved in bacteria
FY152_03200	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY152_03205	COG2202	Pas domain
FY152_03205	COG2205	protein histidine kinase activity
FY152_03215	COG0308	aminopeptidase N
FY152_03235	COG0443	Heat shock 70 kDa protein
FY152_03245	COG0300	oxidoreductase activity
FY152_03255	COG3920	Histidine kinase
FY152_03255	COG2202	Pas domain
FY152_03270	COG0604	alcohol dehydrogenase
FY152_03275	COG1733	regulation of RNA biosynthetic process
FY152_03280	COG1968	undecaprenyl-diphosphatase activity
FY152_03285	COG2239	Acts as a magnesium transporter
FY152_03290	COG2814	Major facilitator Superfamily
FY152_03320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY152_03345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY152_03380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FY152_03385	COG0741	lytic transglycosylase activity
FY152_03390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_03395	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY152_03400	COG0840	transmembrane signaling receptor activity
FY152_03410	COG1758	RNA polymerase activity
FY152_03430	COG0736	holo-[acyl-carrier-protein] synthase activity
FY152_03435	COG0681	Belongs to the peptidase S26 family
FY152_03440	COG0571	ribonuclease III activity
FY152_03445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY152_03450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY152_03455	COG0784	Response regulator, receiver
FY152_03460	COG1381	Involved in DNA repair and RecF pathway recombination
FY152_03470	COG2226	methyltransferase
FY152_03480	COG1418	mRNA catabolic process
FY152_03490	COG0346	lactoylglutathione lyase activity
FY152_03505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_03510	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY152_03515	COG0668	transmembrane transport
FY152_03525	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY152_03555	COG1742	UPF0060 membrane protein
FY152_03570	COG1183	phosphatidylcholine synthase activity
FY152_03575	COG0688	phosphatidylethanolamine metabolic process
FY152_03580	COG5265	(ABC) transporter
FY152_03625	COG2852	Protein conserved in bacteria
FY152_03630	COG0215	cysteine-tRNA ligase activity
FY152_03635	COG4221	oxidoreductase activity
FY152_03640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY152_03645	COG1286	toxin biosynthetic process
FY152_03665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY152_03675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY152_03685	COG0305	Participates in initiation and elongation during chromosome replication
FY152_03705	COG0359	binds to the 23S rRNA
FY152_03715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY152_03720	COG0360	Binds together with S18 to 16S ribosomal RNA
FY152_03725	COG0667	Aldo Keto reductase
FY152_03730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY152_03740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY152_03745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY152_03750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY152_03755	COG1561	YicC-like family, N-terminal region
FY152_03760	COG0194	GDP metabolic process
FY152_03765	COG0400	carboxylic ester hydrolase activity
FY152_03770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY152_03775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY152_03785	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY152_03800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY152_03825	COG3300	MHYT domain
FY152_03825	COG5001	Diguanylate cyclase
FY152_03830	COG4191	Histidine kinase
FY152_03845	COG0488	(ABC) transporter
FY152_03850	COG3706	GGDEF domain
FY152_03860	COG0105	UTP biosynthetic process
FY152_03880	COG0314	molybdopterin synthase activity
FY152_03890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY152_03895	COG0322	excinuclease ABC activity
FY152_03900	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_03910	COG0625	glutathione transferase activity
FY152_03925	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY152_03930	COG0243	molybdopterin cofactor binding
FY152_03945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY152_03950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY152_03955	COG0628	permease
FY152_03965	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY152_03970	COG0248	Ppx GppA phosphatase
FY152_04000	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY152_04010	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY152_04015	COG0477	Major facilitator Superfamily
FY152_04020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY152_04030	COG0840	transmembrane signaling receptor activity
FY152_04035	COG0659	secondary active sulfate transmembrane transporter activity
FY152_04045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY152_04050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY152_04060	COG0113	porphobilinogen synthase activity
FY152_04080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY152_04085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY152_04090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY152_04090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY152_04100	COG1280	lysine exporter protein (LysE YggA)
FY152_04105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY152_04110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY152_04115	COG2814	Major facilitator Superfamily
FY152_04120	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY152_04140	COG0416	fatty acid biosynthetic process
FY152_04145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY152_04150	COG0776	regulation of translation
FY152_04190	COG3237	CsbD-like
FY152_04195	COG3916	Acyl-homoserine-lactone synthase
FY152_04275	COG3685	Protein conserved in bacteria
FY152_04365	COG0582	viral genome integration into host DNA
FY152_04385	COG0601	transmembrane transport
FY152_04390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_04395	COG0444	Belongs to the ABC transporter superfamily
FY152_04400	COG4608	Belongs to the ABC transporter superfamily
FY152_04405	COG0747	negative chemotaxis
FY152_04415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY152_04420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY152_04435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY152_04440	COG0583	DNA-binding transcription factor activity
FY152_04450	COG0737	Belongs to the 5'-nucleotidase family
FY152_04475	COG2897	thiosulfate sulfurtransferase activity
FY152_04490	COG0415	Belongs to the DNA photolyase family
FY152_04500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY152_04520	COG0583	DNA-binding transcription factor activity
FY152_04540	COG3932	Exopolysaccharide synthesis, ExoD
FY152_04545	COG1238	metal cluster binding
FY152_04615	COG1612	heme a metabolic process
FY152_04625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY152_04630	COG0010	Belongs to the arginase family
FY152_04635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY152_04640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY152_04650	COG1832	CoA-binding protein
FY152_04670	COG2124	cytochrome p450
FY152_04680	COG0740	serine-type endopeptidase activity
FY152_04685	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY152_04690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY152_04700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY152_04725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY152_04730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY152_04735	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY152_04745	COG0649	NAD binding
FY152_04755	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY152_04760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY152_04770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY152_04775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY152_04785	COG0713	ATP synthesis coupled electron transport
FY152_04800	COG1007	ATP synthesis coupled electron transport
FY152_04805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY152_04805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY152_04820	COG0442	prolyl-tRNA aminoacylation
FY152_04830	COG1136	(ABC) transporter
FY152_04845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY152_04855	COG0784	Response regulator, receiver
FY152_04870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY152_04875	COG0477	Major facilitator Superfamily
FY152_04890	COG0557	exoribonuclease II activity
FY152_04895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY152_04905	COG0758	DNA mediated transformation
FY152_04910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY152_04920	COG0540	Belongs to the ATCase OTCase family
FY152_04930	COG1960	acyl-CoA dehydrogenase activity
FY152_04935	COG0456	acetyltransferase
FY152_04955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY152_04960	COG2824	Alkylphosphonate utilization operon protein PhnA
FY152_04965	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY152_04970	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY152_04975	COG0154	amidase activity
FY152_04980	COG3811	Belongs to the UPF0386 family
FY152_04995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY152_05005	COG0456	acetyltransferase
FY152_05020	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY152_05025	COG0439	Biotin carboxylase
FY152_05030	COG0511	ligase activity, forming carbon-carbon bonds
FY152_05035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY152_05045	COG0436	Aminotransferase
FY152_05065	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_05070	COG1530	ribonuclease E activity
FY152_05080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY152_05100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY152_05105	COG0384	phenazine biosynthesis protein PhzF
FY152_05120	COG0633	Ferredoxin
FY152_05130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY152_05135	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY152_05140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY152_05150	COG3768	UPF0283 membrane protein
FY152_05155	COG3106	COG3106 Predicted ATPase
FY152_05180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY152_05215	COG0537	adenosine 5'-monophosphoramidase activity
FY152_05240	COG0052	Belongs to the universal ribosomal protein uS2 family
FY152_05245	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY152_05250	COG0528	UMP kinase activity
FY152_05255	COG0233	cytoplasmic translational termination
FY152_05260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY152_05270	COG0750	zinc metalloprotease
FY152_05275	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY152_05280	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY152_05285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY152_05290	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY152_05295	COG3494	Protein of unknown function (DUF1009)
FY152_05300	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY152_05305	COG2186	Transcriptional regulator
FY152_05315	COG0765	amino acid transport
FY152_05320	COG0765	amino acid transport
FY152_05330	COG0372	Belongs to the citrate synthase family
FY152_05345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY152_05355	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY152_05360	COG0148	phosphopyruvate hydratase activity
FY152_05370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY152_05375	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY152_05375	COG0022	dehydrogenase e1 component
FY152_05380	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY152_05390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY152_05400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY152_05405	COG0697	spore germination
FY152_05420	COG2867	negative regulation of translational initiation
FY152_05425	COG1546	Belongs to the CinA family
FY152_05430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY152_05430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY152_05440	COG3852	Histidine kinase
FY152_05445	COG2204	response regulator
FY152_05450	COG5000	phosphorelay sensor kinase activity
FY152_05455	COG2204	response regulator
FY152_05460	COG0569	domain protein
FY152_05465	COG1923	regulation of RNA biosynthetic process
FY152_05470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY152_05475	COG3956	TIGRFAM MazG family protein
FY152_05485	COG1648	precorrin-2 dehydrogenase activity
FY152_05485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY152_05525	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY152_05525	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY152_05530	COG0509	glycine decarboxylation via glycine cleavage system
FY152_05535	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY152_05560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY152_05565	COG0564	pseudouridine synthase activity
FY152_05585	COG0251	oxidation-reduction process
FY152_05590	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY152_05600	COG1671	Belongs to the UPF0178 family
FY152_05615	COG0450	alkyl hydroperoxide reductase
FY152_05625	COG0625	glutathione transferase activity
FY152_05670	COG1595	DNA-templated transcription, initiation
FY152_05680	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FY152_05685	COG0431	NADPH-dependent FMN reductase
FY152_05695	COG0798	PFAM Bile acid sodium symporter
FY152_05705	COG2226	methyltransferase
FY152_05710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_05715	COG0601	transmembrane transport
FY152_05740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY152_05740	COG0321	lipoyl(octanoyl) transferase activity
FY152_05745	COG0084	hydrolase, TatD family'
FY152_05750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY152_05760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY152_05810	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY152_05815	COG2095	MarC family integral membrane protein
FY152_05820	COG0517	IMP dehydrogenase activity
FY152_05820	COG0617	tRNA 3'-terminal CCA addition
FY152_05820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY152_05825	COG0629	single-stranded DNA binding
FY152_05830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY152_05845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY152_05865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY152_05870	COG1121	(ABC) transporter
FY152_05880	COG1609	Transcriptional regulator
FY152_05890	COG0667	Aldo Keto reductase
FY152_05905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY152_05985	COG2239	Acts as a magnesium transporter
FY152_05990	COG0243	molybdopterin cofactor binding
FY152_06000	COG0242	peptide deformylase activity
FY152_06010	COG2202	Pas domain
FY152_06010	COG2205	protein histidine kinase activity
FY152_06020	COG0321	lipoyl(octanoyl) transferase activity
FY152_06025	COG1064	alcohol dehydrogenase
FY152_06055	COG1862	Preprotein translocase
FY152_06065	COG1045	serine acetyltransferase
FY152_06080	COG2124	cytochrome p450
FY152_06095	COG0596	Alpha beta hydrolase
FY152_06110	COG0626	cystathionine gamma-synthase activity
FY152_06115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_06120	COG4597	amino acid ABC transporter
FY152_06125	COG0765	amino acid transport
FY152_06130	COG1126	abc transporter atp-binding protein
FY152_06145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY152_06160	COG0436	Aminotransferase
FY152_06190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY152_06200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY152_06205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY152_06210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY152_06230	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY152_06235	COG1489	DNA binding
FY152_06240	COG0024	Methionine aminopeptidase
FY152_06245	COG2003	Belongs to the UPF0758 family
FY152_06260	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY152_06275	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY152_06280	COG0546	phosphoglycolate phosphatase activity
FY152_06290	COG0114	fumarate hydratase activity
FY152_06295	COG2755	lipolytic protein G-D-S-L family
FY152_06295	COG0657	acetylesterase activity
FY152_06300	COG0504	CTP synthase activity
FY152_06310	COG0149	triose-phosphate isomerase activity
FY152_06320	COG0187	DNA topoisomerase II activity
FY152_06330	COG0740	serine-type endopeptidase activity
FY152_06340	COG0640	Transcriptional regulator
FY152_06345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY152_06350	COG0745	RESPONSE REGULATOR receiver
FY152_06360	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY152_06360	COG3264	Mechanosensitive ion channel
FY152_06430	COG1127	ABC transporter
FY152_06435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY152_06440	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_06450	COG0280	phosphate acetyltransferase
FY152_06450	COG0281	malic enzyme
FY152_06470	COG0778	Nitroreductase
FY152_06475	COG0823	Involved in the tonB-independent uptake of proteins
FY152_06490	COG1368	sulfuric ester hydrolase activity
FY152_06515	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY152_06535	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY152_06555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY152_06585	COG0343	queuine tRNA-ribosyltransferase activity
FY152_06590	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY152_06605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY152_06620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY152_06625	COG0134	indole-3-glycerol-phosphate synthase activity
FY152_06630	COG0315	cyclic pyranopterin monophosphate synthase activity
FY152_06635	COG0303	'Molybdopterin
FY152_06640	COG3706	GGDEF domain
FY152_06650	COG0475	glutathione-regulated potassium exporter activity
FY152_06650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY152_06660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY152_06670	COG2814	Major facilitator Superfamily
FY152_06675	COG0746	molybdenum cofactor guanylyltransferase activity
FY152_06680	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY152_06685	COG0739	heme binding
FY152_06690	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY152_06695	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY152_06700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY152_06705	COG0805	protein transport
FY152_06710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY152_06715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY152_06720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY152_06725	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY152_06730	COG1472	Belongs to the glycosyl hydrolase 3 family
FY152_06740	COG0018	arginyl-trna synthetase
FY152_06745	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY152_06750	COG0316	Belongs to the HesB IscA family
FY152_06775	COG0525	valine-tRNA ligase activity
FY152_06785	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY152_06815	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY152_06820	COG1546	Belongs to the CinA family
FY152_06820	COG1058	Belongs to the CinA family
FY152_06825	COG0589	response to stress
FY152_06830	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY152_06835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY152_06845	COG1914	H( )-stimulated, divalent metal cation uptake system
FY152_06860	COG1132	(ABC) transporter
FY152_06865	COG0628	permease
FY152_06900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY152_06910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY152_06920	COG0302	gtp cyclohydrolase
FY152_06925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY152_06930	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY152_06935	COG0516	GMP reductase activity
FY152_06935	COG0517	IMP dehydrogenase activity
FY152_06965	COG1760	l-serine dehydratase
FY152_06995	COG0583	DNA-binding transcription factor activity
FY152_07005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY152_07005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY152_07015	COG0347	Belongs to the P(II) protein family
FY152_07020	COG0174	glutamine synthetase
FY152_07050	COG0697	spore germination
FY152_07060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY152_07070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY152_07100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY152_07105	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY152_07110	COG2186	Transcriptional regulator
FY152_07120	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY152_07125	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY152_07130	COG3845	ABC transporter
FY152_07135	COG1183	phosphatidylcholine synthase activity
FY152_07140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY152_07145	COG0679	Auxin Efflux Carrier
FY152_07150	COG0785	Cytochrome C biogenesis protein
FY152_07180	COG0501	Belongs to the peptidase M48B family
FY152_07215	COG1609	Transcriptional regulator
FY152_07215	COG2207	Transcriptional regulator
FY152_07315	COG0346	lactoylglutathione lyase activity
FY152_07320	COG1278	Cold shock
FY152_07370	COG0577	efflux transmembrane transporter activity
FY152_07370	COG1136	(ABC) transporter
FY152_07375	COG0577	efflux transmembrane transporter activity
FY152_07375	COG1136	(ABC) transporter
FY152_07390	COG2151	metal-sulfur cluster biosynthetic enzyme
FY152_07395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY152_07400	COG0719	Fe-S assembly protein
FY152_07405	COG0396	ATPase activity
FY152_07410	COG0719	Fe-S assembly protein
FY152_07415	COG1104	cysteine desulfurase activity
FY152_07420	COG2945	thiolester hydrolase activity
FY152_07425	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY152_07430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY152_07440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY152_07445	COG2833	Protein of unknown function (DUF455)
FY152_07450	COG0739	heme binding
FY152_07455	COG0513	Belongs to the DEAD box helicase family
FY152_07480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY152_07490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY152_07495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY152_07500	COG0047	phosphoribosylformylglycinamidine synthase activity
FY152_07515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY152_07525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY152_07550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY152_07555	COG2814	Major facilitator Superfamily
FY152_07560	COG0483	inositol monophosphate 1-phosphatase activity
FY152_07565	COG0483	inositol monophosphate 1-phosphatase activity
FY152_07570	COG0037	tRNA processing
FY152_07575	COG2066	Belongs to the glutaminase family
FY152_07580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY152_07585	COG0861	Integral membrane protein TerC family
FY152_07600	COG1280	lysine exporter protein (LysE YggA)
FY152_07610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY152_07615	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY152_07625	COG0538	isocitrate dehydrogenase activity
FY152_07650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY152_07655	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY152_07665	COG2313	pseudouridylate synthase activity
FY152_07675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_07680	COG4215	(ABC) transporter
FY152_07690	COG5425	PFAM Usg family protein
FY152_07700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY152_07705	COG1522	sequence-specific DNA binding
FY152_07710	COG1573	uracil-dna glycosylase
FY152_07720	COG2202	Pas domain
FY152_07720	COG2205	protein histidine kinase activity
FY152_07730	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY152_07735	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY152_07750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY152_07755	COG0842	Transport permease protein
FY152_07760	COG1131	(ABC) transporter
FY152_07765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY152_07765	COG0730	response to heat
FY152_07775	COG0840	transmembrane signaling receptor activity
FY152_07775	COG0840	transmembrane signaling receptor activity
FY152_07785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY152_07810	COG0129	dihydroxy-acid dehydratase activity
FY152_07815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY152_07820	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY152_07830	COG3739	integral membrane protein
FY152_07840	COG0203	ribosomal protein L17
FY152_07845	COG0202	RNA polymerase activity
FY152_07850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY152_07855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY152_07860	COG0563	adenylate kinase activity
FY152_07865	COG0201	protein transport
FY152_07870	COG0200	Binds to the 23S rRNA
FY152_07875	COG1841	ribosomal large subunit assembly
FY152_07880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY152_07885	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY152_07890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY152_07895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY152_07900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY152_07905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY152_07910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY152_07915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY152_07920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY152_07925	COG0255	Belongs to the universal ribosomal protein uL29 family
FY152_07930	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY152_07935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY152_07940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY152_07945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY152_07950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY152_07955	COG0089	rRNA binding
FY152_07960	COG0088	Forms part of the polypeptide exit tunnel
FY152_07965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY152_07970	COG0051	transcription antitermination factor activity, RNA binding
FY152_07975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY152_07980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY152_07985	COG0049	tRNA binding
FY152_07990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY152_08010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY152_08015	COG0085	RNA polymerase activity
FY152_08020	COG0222	ribosome binding
FY152_08025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY152_08030	COG0081	regulation of translation
FY152_08035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY152_08045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY152_08060	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY152_08065	COG0861	Integral membrane protein TerC family
FY152_08085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY152_08105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY152_08145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_08175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY152_08180	COG1607	acyl-coa hydrolase
FY152_08205	COG2910	NAD(P)H-binding
FY152_08210	COG1733	regulation of RNA biosynthetic process
FY152_08225	COG0556	nucleotide-excision repair
FY152_08235	COG2382	esterase
FY152_08255	COG0484	heat shock protein binding
FY152_08290	COG1840	ABC-type Fe3 transport system, periplasmic component
FY152_08295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY152_08310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY152_08320	COG2207	Transcriptional regulator
FY152_08325	COG1064	alcohol dehydrogenase
FY152_08330	COG1252	NADH dehydrogenase
FY152_08335	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY152_08340	COG2197	response regulator
FY152_08345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY152_08350	COG1090	epimerase
FY152_08390	COG0656	L-ascorbic acid biosynthetic process
FY152_08405	COG0440	acetolactate synthase activity
FY152_08410	COG0028	Belongs to the TPP enzyme family
FY152_08420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY152_08445	COG0330	HflC and HflK could
FY152_08450	COG0330	HflC and HflK could
FY152_08460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY152_08500	COG0277	FAD linked oxidase domain protein
FY152_08505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY152_08560	COG1335	isochorismatase
FY152_08585	COG2264	protein methyltransferase activity
FY152_08590	COG1999	signal sequence binding
FY152_08600	COG0835	chemotaxis
FY152_08610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY152_08615	COG0583	DNA-binding transcription factor activity
FY152_08625	COG0456	acetyltransferase
FY152_08635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY152_08640	COG1280	lysine exporter protein (LysE YggA)
FY152_08645	COG0497	DNA recombination
FY152_08650	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY152_08660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY152_08665	COG0849	cell division
FY152_08670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY152_08675	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY152_08680	COG0477	Major facilitator Superfamily
FY152_08690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY152_08695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY152_08700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY152_08710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY152_08715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY152_08725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY152_08740	COG0275	rRNA processing
FY152_08745	COG2001	Belongs to the MraZ family
FY152_08760	COG0754	glutathionylspermidine amidase activity
FY152_08785	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY152_08820	COG4106	trans-aconitate 2-methyltransferase activity
FY152_08840	COG2226	methyltransferase
FY152_08850	COG2267	carboxylic ester hydrolase activity
FY152_08855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY152_08885	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_08890	COG2814	Major facilitator Superfamily
FY152_08915	COG1012	belongs to the aldehyde dehydrogenase family
FY152_08920	COG0174	glutamine synthetase
FY152_08925	COG0531	amino acid
FY152_08935	COG1737	Transcriptional regulator
FY152_08955	COG3842	ATPase activity
FY152_09015	COG2968	Membrane
FY152_09025	COG0432	Pfam Uncharacterised protein family UPF0047
FY152_09040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY152_09045	COG0358	DNA primase activity
FY152_09070	COG0505	Belongs to the CarA family
FY152_09075	COG0534	Mate efflux family protein
FY152_09090	COG2321	neutral zinc metallopeptidase
FY152_09105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY152_09110	COG3706	GGDEF domain
FY152_09115	COG1573	uracil-dna glycosylase
FY152_09125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY152_09135	COG1522	sequence-specific DNA binding
FY152_09140	COG0492	ferredoxin-NADP+ reductase activity
FY152_09145	COG0583	DNA-binding transcription factor activity
FY152_09155	COG1902	pentaerythritol trinitrate reductase activity
FY152_09180	COG0387	Pfam Sodium calcium exchanger
FY152_09190	COG0436	Aminotransferase
FY152_09195	COG2200	EAL domain
FY152_09195	COG2199	diguanylate cyclase activity
FY152_09210	COG1278	Cold shock
FY152_09215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY152_09225	COG1846	Transcriptional regulator
FY152_09230	COG0745	RESPONSE REGULATOR receiver
FY152_09235	COG2205	protein histidine kinase activity
FY152_09240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY152_09265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY152_09275	COG1496	oxidoreductase activity
FY152_09280	COG0006	proline dipeptidase activity
FY152_09290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY152_09315	COG0840	transmembrane signaling receptor activity
FY152_09320	COG1012	belongs to the aldehyde dehydrogenase family
FY152_09330	COG5001	Diguanylate cyclase
FY152_09330	COG3300	MHYT domain
FY152_09335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY152_09340	COG5001	Diguanylate cyclase
FY152_09350	COG0193	aminoacyl-tRNA hydrolase activity
FY152_09360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY152_09385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY152_09390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY152_09390	COG2857	Cytochrome c1
FY152_09410	COG1132	(ABC) transporter
FY152_09415	COG1132	(ABC) transporter
FY152_09420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY152_09425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY152_09440	COG0408	coproporphyrinogen oxidase activity
FY152_09455	COG0617	tRNA 3'-terminal CCA addition
FY152_09470	COG0714	Associated with various cellular activities
FY152_09490	COG0454	-acetyltransferase
FY152_09510	COG0477	Major facilitator Superfamily
FY152_09520	COG0435	Glutathione S-transferase
FY152_09525	COG0494	nUDIX hydrolase
FY152_09535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY152_09550	COG3135	benzoate transporter
FY152_09560	COG4944	Protein of unknown function (DUF1109)
FY152_09575	COG0740	serine-type endopeptidase activity
FY152_09590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY152_09595	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY152_09620	COG4175	Glycine betaine
FY152_09635	COG1435	thymidine kinase activity
FY152_09650	COG2197	response regulator
FY152_09655	COG2862	Uncharacterized protein family, UPF0114
FY152_09660	COG4771	TonB-dependent receptor
FY152_09660	COG1629	transport
FY152_09670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY152_09670	COG0512	Glutamine amidotransferase of anthranilate synthase
FY152_09680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY152_09690	COG0366	Alpha amylase catalytic
FY152_09695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_09715	COG1160	GTP binding
FY152_09735	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY152_09745	COG0024	Methionine aminopeptidase
FY152_09755	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_09765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY152_09775	COG0583	DNA-binding transcription factor activity
FY152_09790	COG0402	S-adenosylhomocysteine deaminase activity
FY152_09800	COG1304	FMN binding
FY152_09810	COG1309	transcriptional regulator
FY152_09815	COG1686	Belongs to the peptidase S11 family
FY152_09825	COG2351	hydroxyisourate hydrolase activity
FY152_09830	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY152_09855	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY152_09865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_09865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY152_09870	COG5002	protein histidine kinase activity
FY152_09870	COG0784	Response regulator, receiver
FY152_09870	COG2205	protein histidine kinase activity
FY152_09875	COG0513	Belongs to the DEAD box helicase family
FY152_09885	COG2259	Doxx family
FY152_09890	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_09900	COG2308	Evidence 4 Homologs of previously reported genes of
FY152_09910	COG1305	Transglutaminase-like
FY152_09935	COG4214	carbohydrate transport
FY152_09945	COG4213	ABC transporter substrate-binding protein
FY152_09985	COG0300	oxidoreductase activity
FY152_09990	COG0483	inositol monophosphate 1-phosphatase activity
FY152_10005	COG1175	transmembrane transport
FY152_10030	COG1063	alcohol dehydrogenase
FY152_10040	COG1070	Carbohydrate kinase
FY152_10045	COG1309	transcriptional regulator
FY152_10060	COG0840	transmembrane signaling receptor activity
FY152_10085	COG1215	transferase activity, transferring glycosyl groups
FY152_10100	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FY152_10115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY152_10120	COG2346	COG2346, Truncated hemoglobins
FY152_10140	COG1309	transcriptional regulator
FY152_10160	COG0494	nUDIX hydrolase
FY152_10170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_10175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_10205	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY152_10210	COG0830	nickel cation binding
FY152_10215	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY152_10230	COG0804	urea catabolic process
FY152_10235	COG1442	glycosyl transferase family 8
FY152_10240	COG3755	Protein conserved in bacteria
FY152_10250	COG0832	Belongs to the urease beta subunit family
FY152_10255	COG3813	Protein conserved in bacteria
FY152_10260	COG0831	urea catabolic process
FY152_10265	COG0829	nickel cation binding
FY152_10280	COG0411	ABC transporter
FY152_10290	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY152_10305	COG0174	glutamine synthetase
FY152_10310	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_10315	COG0784	Response regulator, receiver
FY152_10315	COG5002	protein histidine kinase activity
FY152_10315	COG2198	Histidine kinase
FY152_10360	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY152_10435	COG0564	pseudouridine synthase activity
FY152_10445	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY152_10455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY152_10480	COG0346	lactoylglutathione lyase activity
FY152_10490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY152_10500	COG2832	Protein of unknown function (DUF454)
FY152_10505	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY152_10510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_10515	COG4558	Periplasmic binding protein
FY152_10525	COG3721	Heme iron utilization protein
FY152_10540	COG3657	addiction module killer protein
FY152_10550	COG2205	protein histidine kinase activity
FY152_10590	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_10595	COG4605	iron ion homeostasis
FY152_10600	COG4604	ABC transporter, ATP-binding protein
FY152_10605	COG0783	Belongs to the Dps family
FY152_10620	COG0583	DNA-binding transcription factor activity
FY152_10625	COG0657	acetylesterase activity
FY152_10650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY152_10655	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY152_10660	COG0288	reversible hydration of carbon dioxide
FY152_10670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY152_10690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY152_10695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY152_10700	COG0778	Nitroreductase
FY152_10705	COG2267	carboxylic ester hydrolase activity
FY152_10710	COG0251	oxidation-reduction process
FY152_10715	COG1335	isochorismatase
FY152_10720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_10730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_10745	COG1175	transmembrane transport
FY152_10750	COG0395	ABC-type sugar transport system, permease component
FY152_10755	COG3842	ATPase activity
FY152_10760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_10770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY152_10785	COG4608	Belongs to the ABC transporter superfamily
FY152_10790	COG0444	Belongs to the ABC transporter superfamily
FY152_10795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_10800	COG0601	transmembrane transport
FY152_10835	COG2814	Major facilitator Superfamily
FY152_10855	COG2159	amidohydrolase
FY152_10890	COG0745	RESPONSE REGULATOR receiver
FY152_10900	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY152_10900	COG1902	pentaerythritol trinitrate reductase activity
FY152_10910	COG0745	RESPONSE REGULATOR receiver
FY152_10915	COG4232	protein-disulfide reductase activity
FY152_10920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY152_10920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY152_10930	COG1388	LysM domain
FY152_10930	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_10935	COG3842	ATPase activity
FY152_10945	COG1840	ABC-type Fe3 transport system, periplasmic component
FY152_10950	COG1840	ABC-type Fe3 transport system, periplasmic component
FY152_10955	COG0745	RESPONSE REGULATOR receiver
FY152_10960	COG4191	Histidine kinase
FY152_10960	COG0784	Response regulator, receiver
FY152_10965	COG0662	Cupin 2, conserved barrel domain protein
FY152_10965	COG2207	Transcriptional regulator
FY152_10970	COG0667	Aldo Keto reductase
FY152_10975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY152_10980	COG0583	DNA-binding transcription factor activity
FY152_10995	COG1845	cytochrome c oxidase, subunit III
FY152_11000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY152_11005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY152_11070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY152_11080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_11085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY152_11095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY152_11105	COG1509	lysine 2,3-aminomutase activity
FY152_11125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_11130	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY152_11135	COG4149	molybdate abc transporter
FY152_11140	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY152_11155	COG2022	thiamine diphosphate biosynthetic process
FY152_11170	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY152_11175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY152_11185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY152_11205	COG1132	(ABC) transporter
FY152_11210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY152_11255	COG4166	transmembrane transport
FY152_11260	COG0601	transmembrane transport
FY152_11265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_11275	COG0438	transferase activity, transferring glycosyl groups
FY152_11280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY152_11285	COG3142	Participates in the control of copper homeostasis
FY152_11305	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_11310	COG1737	Transcriptional regulator
FY152_11320	COG3842	ATPase activity
FY152_11330	COG0395	ABC-type sugar transport system, permease component
FY152_11345	COG2188	Transcriptional regulator
FY152_11350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY152_11355	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY152_11360	COG1940	carbohydrate kinase activity
FY152_11370	COG0671	phosphoesterase, PA-phosphatase related
FY152_11375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY152_11380	COG0156	8-amino-7-oxononanoate synthase activity
FY152_11390	COG0729	surface antigen
FY152_11400	COG0835	chemotaxis
FY152_11410	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY152_11415	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY152_11420	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY152_11425	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY152_11430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY152_11435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY152_11450	COG4974	Belongs to the 'phage' integrase family
FY152_11475	COG1280	lysine exporter protein (LysE YggA)
FY152_11485	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY152_11490	COG0567	Dehydrogenase, E1 component
FY152_11495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY152_11500	COG0045	succinate-CoA ligase (ADP-forming) activity
FY152_11505	COG0039	L-malate dehydrogenase activity
FY152_11510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY152_11545	COG2264	protein methyltransferase activity
FY152_11560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY152_11565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY152_11570	COG0181	hydroxymethylbilane synthase activity
FY152_11610	COG1872	DUF167
FY152_11615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY152_11625	COG1217	gtp-binding protein TYPA
FY152_11630	COG0339	signal peptide processing
FY152_11640	COG1846	Transcriptional regulator
FY152_11650	COG0137	argininosuccinate synthase activity
FY152_11665	COG1280	lysine exporter protein (LysE YggA)
FY152_11670	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY152_11675	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY152_11685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY152_11700	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY152_11705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY152_11710	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY152_11720	COG4181	ATPase activity
FY152_11730	COG0670	Belongs to the BI1 family
FY152_11745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY152_11750	COG4133	protoheme IX ABC transporter activity
FY152_11755	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY152_11760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY152_11785	COG2917	probably involved in intracellular septation
FY152_11790	COG0552	protein localization to endoplasmic reticulum
FY152_11795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY152_11800	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY152_11810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY152_11815	COG0287	Prephenate dehydrogenase
FY152_11815	COG1605	Chorismate mutase
FY152_11820	COG0228	four-way junction DNA binding
FY152_11825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY152_11830	COG0336	Belongs to the RNA methyltransferase TrmD family
FY152_11840	COG0335	large ribosomal subunit rRNA binding
FY152_11845	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY152_11850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_11865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY152_11885	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY152_11905	COG0488	(ABC) transporter
FY152_11915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY152_11925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY152_11930	COG0142	geranyltranstransferase activity
FY152_11935	COG2885	chlorophyll binding
FY152_11940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY152_11945	COG2223	nitrite transmembrane transporter activity
FY152_11950	COG1349	DNA-binding transcription factor activity
FY152_11955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY152_11960	COG2197	response regulator
FY152_11965	COG1132	(ABC) transporter
FY152_11970	COG3459	Glycosyltransferase 36 associated
FY152_11975	COG1473	amidohydrolase
FY152_11980	COG0579	oxidoreductase
FY152_11990	COG0129	dihydroxy-acid dehydratase activity
FY152_11995	COG2084	Dehydrogenase
FY152_12000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY152_12005	COG0277	FAD linked oxidase domain protein
FY152_12010	COG2186	Transcriptional regulator
FY152_12020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY152_12025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY152_12030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY152_12035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY152_12045	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY152_12050	COG0495	leucyl-tRNA aminoacylation
FY152_12065	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY152_12080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY152_12085	COG1946	Acyl-CoA thioesterase
FY152_12090	COG0347	Belongs to the P(II) protein family
FY152_12095	COG0004	ammonium transporteR
FY152_12100	COG1674	ftsk spoiiie
FY152_12105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY152_12120	COG0745	RESPONSE REGULATOR receiver
FY152_12130	COG1329	Transcriptional regulator
FY152_12135	COG2902	Dehydrogenase
FY152_12140	COG2270	Major facilitator Superfamily
FY152_12155	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_12170	COG0494	nUDIX hydrolase
FY152_12180	COG0793	Belongs to the peptidase S41A family
FY152_12190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY152_12195	COG0799	negative regulation of ribosome biogenesis
FY152_12200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY152_12205	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY152_12210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY152_12215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY152_12230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY152_12235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY152_12260	COG0066	3-isopropylmalate dehydratase activity
FY152_12265	COG0473	3-isopropylmalate dehydrogenase activity
FY152_12270	COG1858	cytochrome C peroxidase
FY152_12275	COG1797	cobyrinic acid a,c-diamide synthase activity
FY152_12285	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY152_12350	COG1492	cobalamin metabolic process
FY152_12365	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_12370	COG3254	rhamnose metabolic process
FY152_12375	COG0246	Mannitol dehydrogenase
FY152_12380	COG1063	alcohol dehydrogenase
FY152_12400	COG4214	carbohydrate transport
FY152_12405	COG1129	ABC transporter
FY152_12410	COG2186	Transcriptional regulator
FY152_12415	COG2721	sulfolactate sulfo-lyase activity
FY152_12420	COG0138	bifunctional purine biosynthesis protein purh
FY152_12430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY152_12430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY152_12435	COG0501	Belongs to the peptidase M48B family
FY152_12455	COG0357	Ribosomal RNA small subunit methyltransferase G
FY152_12460	COG0445	tRNA wobble uridine modification
FY152_12465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY152_12470	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY152_12475	COG1981	membrane
FY152_12480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY152_12485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY152_12490	COG0424	maF-like protein
FY152_12495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY152_12500	COG0237	dephospho-CoA kinase activity
FY152_12510	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY152_12515	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY152_12525	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY152_12550	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY152_12565	COG0135	phosphoribosylanthranilate isomerase activity
FY152_12570	COG0133	tryptophan synthase activity
FY152_12575	COG0159	tryptophan synthase activity
FY152_12580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY152_12585	COG0285	dihydrofolate synthase activity
FY152_12595	COG1074	ATP-dependent DNA helicase activity
FY152_12605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY152_12615	COG2205	protein histidine kinase activity
FY152_12625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY152_12630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY152_12635	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY152_12635	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY152_12640	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY152_12645	COG0642	Histidine kinase
FY152_12650	COG0745	RESPONSE REGULATOR receiver
FY152_12655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY152_12665	COG1652	LysM domain
FY152_12670	COG1072	(Pantothenic acid kinase))
FY152_12675	COG0140	phosphoribosyl-ATP diphosphatase activity
FY152_12680	COG0107	imidazoleglycerol-phosphate synthase activity
FY152_12685	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY152_12690	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY152_12700	COG0131	Imidazoleglycerol-phosphate dehydratase
FY152_12705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY152_12710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY152_12720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY152_12735	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY152_12745	COG1643	Atp-dependent helicase
FY152_12780	COG0514	ATP-dependent DNA helicase (RecQ)
FY152_12805	COG1072	(Pantothenic acid kinase))
FY152_12815	COG1780	Probably involved in ribonucleotide reductase function
FY152_12835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY152_12865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_12875	COG2813	Specifically methylates the guanine in position
FY152_12880	COG1185	polyribonucleotide nucleotidyltransferase activity
FY152_12885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY152_12890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY152_12895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY152_12900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY152_12900	COG3064	Membrane
FY152_12915	COG0779	Required for maturation of 30S ribosomal subunits
FY152_12920	COG2814	Major facilitator Superfamily
FY152_12925	COG2951	lytic endotransglycosylase activity
FY152_12930	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY152_12940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY152_12945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY152_12960	COG2816	NAD+ diphosphatase activity
FY152_12965	COG1605	Chorismate mutase
FY152_12965	COG0077	Prephenate dehydratase
FY152_12970	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY152_12975	COG3474	cytochrome
FY152_12985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY152_12990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY152_12995	COG1278	Cold shock
FY152_13000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY152_13010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY152_13010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY152_13020	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY152_13050	COG2900	Belongs to the SlyX family
FY152_13060	COG0484	heat shock protein binding
FY152_13065	COG0443	Heat shock 70 kDa protein
FY152_13090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY152_13095	COG1744	ABC transporter substrate-binding protein PnrA-like
FY152_13100	COG3845	ABC transporter
FY152_13105	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY152_13110	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY152_13120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY152_13125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY152_13130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY152_13140	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY152_13145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY152_13150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY152_13160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY152_13165	COG1845	cytochrome c oxidase, subunit III
FY152_13170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY152_13180	COG0477	Major facilitator Superfamily
FY152_13185	COG0067	glutamate synthase
FY152_13185	COG0069	glutamate synthase activity
FY152_13185	COG0070	glutamate synthase
FY152_13190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY152_13205	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY152_13215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY152_13245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_13265	COG0848	biopolymer transport protein
FY152_13275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY152_13290	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY152_13295	COG3454	Phosphonate metabolism
FY152_13300	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY152_13305	COG3639	organic phosphonate transmembrane transporter activity
FY152_13310	COG3639	organic phosphonate transmembrane transporter activity
FY152_13315	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY152_13320	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY152_13330	COG4778	phosphonate C-P lyase system protein PhnL
FY152_13335	COG4107	phosphonate C-P lyase system protein PhnK
FY152_13340	COG3627	carbon phosphorus lyase activity
FY152_13345	COG3626	phosphonate metabolism
FY152_13350	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY152_13355	COG3624	Phosphonate C-P lyase system protein PhnG
FY152_13360	COG2188	Transcriptional regulator
FY152_13365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY152_13370	COG0837	glucose binding
FY152_13375	COG1803	Methylglyoxal synthase
FY152_13380	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY152_13385	COG4166	transmembrane transport
FY152_13390	COG4174	ABC transporter (Permease)
FY152_13395	COG4239	(ABC) transporter, permease
FY152_13400	COG4172	Belongs to the ABC transporter superfamily
FY152_13405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_13410	COG0174	glutamine synthetase
FY152_13415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_13420	COG3265	gluconokinase activity
FY152_13425	COG1174	glycine betaine transport
FY152_13430	COG1125	glycine betaine transport
FY152_13435	COG1174	glycine betaine transport
FY152_13440	COG1732	Glycine betaine
FY152_13450	COG1959	2 iron, 2 sulfur cluster binding
FY152_13455	COG1840	ABC-type Fe3 transport system, periplasmic component
FY152_13465	COG4269	membrane
FY152_13475	COG0583	DNA-binding transcription factor activity
FY152_13480	COG0697	spore germination
FY152_13495	COG0791	NLP P60 protein
FY152_13505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY152_13545	COG4964	Belongs to the GSP D family
FY152_13590	COG3422	double-strand break repair
FY152_13595	COG3757	hydrolase, family 25
FY152_13600	COG0697	spore germination
FY152_13605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY152_13635	COG0481	GTPase activity
FY152_13640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY152_13655	COG1396	sequence-specific DNA binding
FY152_13670	COG2169	Transcriptional regulator
FY152_13670	COG1917	Cupin 2, conserved barrel domain protein
FY152_13675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY152_13700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY152_13705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY152_13710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY152_13720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY152_13730	COG0072	phenylalanine-tRNA ligase activity
FY152_13730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY152_13735	COG0667	Aldo Keto reductase
FY152_13755	COG4977	sequence-specific DNA binding
FY152_13780	COG1570	exodeoxyribonuclease VII activity
FY152_13785	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_13795	COG1846	Transcriptional regulator
FY152_13800	COG0697	spore germination
FY152_13805	COG2309	aminopeptidase activity
FY152_13815	COG1393	Belongs to the ArsC family
FY152_13825	COG0300	oxidoreductase activity
FY152_13830	COG0500	methyltransferase
FY152_13840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY152_13840	COG0519	Catalyzes the synthesis of GMP from XMP
FY152_13855	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY152_13885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY152_13895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY152_13905	COG1968	undecaprenyl-diphosphatase activity
FY152_13920	COG0284	orotidine-5'-phosphate decarboxylase activity
FY152_13930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY152_13940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY152_13945	COG0792	nuclease activity
FY152_13960	COG1175	transmembrane transport
FY152_13970	COG3842	ATPase activity
FY152_13980	COG0189	ligase activity
FY152_13990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY152_13995	COG1280	lysine exporter protein (LysE YggA)
FY152_14000	COG0756	dUTP diphosphatase activity
FY152_14005	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY152_14010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY152_14025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY152_14030	COG2226	methyltransferase
FY152_14035	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY152_14040	COG1024	Enoyl-CoA hydratase
FY152_14045	COG0268	Binds directly to 16S ribosomal RNA
FY152_14070	COG1335	isochorismatase
FY152_14080	COG0110	maltose O-acetyltransferase activity
FY152_14085	COG5265	(ABC) transporter
FY152_14090	COG3181	Tripartite tricarboxylate transporter family receptor
FY152_14095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY152_14105	COG2204	response regulator
FY152_14110	COG0784	Response regulator, receiver
FY152_14115	COG2198	Histidine kinase
FY152_14115	COG5002	protein histidine kinase activity
FY152_14115	COG0784	Response regulator, receiver
FY152_14125	COG0405	Gamma-glutamyltransferase
FY152_14130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_14135	COG0601	transmembrane transport
FY152_14140	COG0747	negative chemotaxis
FY152_14145	COG2186	Transcriptional regulator
FY152_14150	COG2197	response regulator
FY152_14155	COG3237	CsbD-like
FY152_14175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY152_14180	COG1802	Transcriptional regulator
FY152_14185	COG4608	Belongs to the ABC transporter superfamily
FY152_14190	COG0444	Belongs to the ABC transporter superfamily
FY152_14195	COG0402	S-adenosylhomocysteine deaminase activity
FY152_14205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_14210	COG0601	transmembrane transport
FY152_14215	COG4166	transmembrane transport
FY152_14220	COG0402	S-adenosylhomocysteine deaminase activity
FY152_14235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY152_14245	COG0765	amino acid transport
FY152_14250	COG0765	amino acid transport
FY152_14255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_14270	COG3938	Belongs to the proline racemase family
FY152_14280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_14290	COG0765	amino acid transport
FY152_14305	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY152_14310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_14320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY152_14325	COG0784	Response regulator, receiver
FY152_14340	COG0842	Transport permease protein
FY152_14345	COG0842	Transport permease protein
FY152_14345	COG1129	ABC transporter
FY152_14350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_14355	COG1486	melibiose metabolic process
FY152_14360	COG4172	Belongs to the ABC transporter superfamily
FY152_14365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_14370	COG0601	transmembrane transport
FY152_14375	COG0747	negative chemotaxis
FY152_14380	COG1486	melibiose metabolic process
FY152_14405	COG1940	carbohydrate kinase activity
FY152_14410	COG2182	Extracellular solute-binding protein
FY152_14415	COG1175	transmembrane transport
FY152_14420	COG0395	ABC-type sugar transport system, permease component
FY152_14425	COG0165	Argininosuccinate lyase
FY152_14430	COG3842	ATPase activity
FY152_14435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_14440	COG3119	arylsulfatase activity
FY152_14450	COG0583	DNA-binding transcription factor activity
FY152_14455	COG1012	belongs to the aldehyde dehydrogenase family
FY152_14495	COG0583	DNA-binding transcription factor activity
FY152_14500	COG1120	ATPase activity
FY152_14505	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_14510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_14525	COG4774	siderophore transport
FY152_14530	COG2207	Transcriptional regulator
FY152_14540	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY152_14555	COG5002	protein histidine kinase activity
FY152_14560	COG0745	RESPONSE REGULATOR receiver
FY152_14580	COG1392	Phosphate transport regulator
FY152_14585	COG0306	phosphate transporter
FY152_14590	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY152_14600	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY152_14610	COG5001	Diguanylate cyclase
FY152_14610	COG3300	MHYT domain
FY152_14625	COG2186	Transcriptional regulator
FY152_14630	COG0601	transmembrane transport
FY152_14635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_14640	COG0444	Belongs to the ABC transporter superfamily
FY152_14645	COG4608	Belongs to the ABC transporter superfamily
FY152_14650	COG0210	DNA helicase
FY152_14655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY152_14660	COG4774	siderophore transport
FY152_14665	COG1120	ATPase activity
FY152_14670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_14675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_14690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY152_14715	COG3959	Transketolase, thiamine diphosphate binding domain
FY152_14720	COG3958	Transketolase
FY152_14730	COG0463	Glycosyl transferase, family 2
FY152_14740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FY152_14740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FY152_14750	COG2942	2-epimerase
FY152_14760	COG0859	PFAM glycosyl transferase family 9
FY152_14770	COG0438	transferase activity, transferring glycosyl groups
FY152_14775	COG1132	(ABC) transporter
FY152_14790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_14800	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_14810	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY152_14820	COG0583	DNA-binding transcription factor activity
FY152_14825	COG0667	Aldo Keto reductase
FY152_14830	COG0385	Bile acid
FY152_14860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY152_14880	COG3842	ATPase activity
FY152_14900	COG0300	oxidoreductase activity
FY152_14905	COG0483	inositol monophosphate 1-phosphatase activity
FY152_14910	COG0584	glycerophosphoryl diester phosphodiesterase
FY152_14920	COG4149	molybdate abc transporter
FY152_14925	COG3842	ATPase activity
FY152_14955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY152_14965	COG3842	ATPase activity
FY152_14970	COG1175	transmembrane transport
FY152_14975	COG0395	ABC-type sugar transport system, permease component
FY152_14980	COG1609	Transcriptional regulator
FY152_14990	COG0673	inositol 2-dehydrogenase activity
FY152_14995	COG1082	Xylose isomerase domain protein TIM barrel
FY152_15005	COG1609	Transcriptional regulator
FY152_15010	COG0183	Belongs to the thiolase family
FY152_15015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY152_15025	COG1414	Transcriptional regulator
FY152_15040	COG0583	DNA-binding transcription factor activity
FY152_15045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FY152_15050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY152_15055	COG3485	protocatechuate 3,4-dioxygenase
FY152_15060	COG3485	protocatechuate 3,4-dioxygenase
FY152_15070	COG0765	amino acid transport
FY152_15075	COG0765	amino acid transport
FY152_15080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_15085	COG1126	abc transporter atp-binding protein
FY152_15090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY152_15095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY152_15120	COG4172	Belongs to the ABC transporter superfamily
FY152_15125	COG0747	negative chemotaxis
FY152_15135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_15150	COG0683	leucine binding
FY152_15165	COG0411	ABC transporter
FY152_15180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_15185	COG3962	Belongs to the TPP enzyme family
FY152_15195	COG3718	enzyme involved in inositol metabolism
FY152_15205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY152_15210	COG1609	Transcriptional regulator
FY152_15215	COG1846	Transcriptional regulator
FY152_15225	COG0523	cobalamin synthesis protein
FY152_15255	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY152_15275	COG0800	Aldolase
FY152_15280	COG2954	triphosphatase activity
FY152_15300	COG5001	Diguanylate cyclase
FY152_15300	COG3300	MHYT domain
FY152_15310	COG2011	ABC-type metal ion transport system permease component
FY152_15315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY152_15320	COG0778	Nitroreductase
FY152_15335	COG1879	ABC-type sugar transport system periplasmic component
FY152_15340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_15345	COG1129	ABC transporter
FY152_15355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY152_15360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_15365	COG5002	protein histidine kinase activity
FY152_15365	COG5001	Diguanylate cyclase
FY152_15365	COG3447	MASE1 domain protein
FY152_15370	COG3257	ureidoglycine aminohydrolase activity
FY152_15380	COG5001	Diguanylate cyclase
FY152_15385	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY152_15395	COG0747	negative chemotaxis
FY152_15400	COG0601	transmembrane transport
FY152_15405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_15410	COG0444	Belongs to the ABC transporter superfamily
FY152_15415	COG4608	Belongs to the ABC transporter superfamily
FY152_15420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY152_15430	COG0129	dihydroxy-acid dehydratase activity
FY152_15435	COG1879	ABC-type sugar transport system periplasmic component
FY152_15440	COG1129	ABC transporter
FY152_15445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_15450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_15455	COG2186	Transcriptional regulator
FY152_15480	COG0587	DNA-directed DNA polymerase activity
FY152_15500	COG0673	inositol 2-dehydrogenase activity
FY152_15510	COG3842	ATPase activity
FY152_15515	COG0395	ABC-type sugar transport system, permease component
FY152_15520	COG1175	transmembrane transport
FY152_15525	COG1653	transport
FY152_15535	COG0673	inositol 2-dehydrogenase activity
FY152_15550	COG5001	Diguanylate cyclase
FY152_15555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_15565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY152_15570	COG2894	cell division
FY152_15575	COG0850	regulation of cytokinetic process
FY152_15580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY152_15585	COG2186	Transcriptional regulator
FY152_15590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY152_15600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY152_15605	COG1063	alcohol dehydrogenase
FY152_15610	COG1312	Catalyzes the dehydration of D-mannonate
FY152_15615	COG1054	Belongs to the UPF0176 family
FY152_15625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY152_15630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY152_15630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY152_15635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_15650	COG0625	glutathione transferase activity
FY152_15655	COG4172	Belongs to the ABC transporter superfamily
FY152_15660	COG1921	L-seryl-tRNASec selenium transferase activity
FY152_15675	COG3964	amidohydrolase
FY152_15685	COG0601	transmembrane transport
FY152_15690	COG0747	negative chemotaxis
FY152_15695	COG0438	transferase activity, transferring glycosyl groups
FY152_15730	COG4989	oxidoreductase activity
FY152_15745	COG3842	ATPase activity
FY152_15750	COG1653	transport
FY152_15755	COG1175	transmembrane transport
FY152_15760	COG0395	ABC-type sugar transport system, permease component
FY152_15765	COG1501	Belongs to the glycosyl hydrolase 31 family
FY152_15770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_15775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY152_15780	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY152_15785	COG0352	thiamine-phosphate diphosphorylase activity
FY152_15790	COG0351	phosphomethylpyrimidine kinase
FY152_15795	COG1522	sequence-specific DNA binding
FY152_15800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY152_15805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_15820	COG2204	response regulator
FY152_15825	COG4191	Histidine kinase
FY152_15830	COG1301	dicarboxylic acid transport
FY152_15840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY152_15845	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_15855	COG1473	amidohydrolase
FY152_15875	COG1215	transferase activity, transferring glycosyl groups
FY152_15885	COG2942	2-epimerase
FY152_15910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY152_15920	COG2197	response regulator
FY152_15950	COG3307	-O-antigen
FY152_15955	COG1596	polysaccharide export
FY152_15960	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY152_15970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY152_15975	COG0840	transmembrane signaling receptor activity
FY152_15980	COG1376	ErfK ybiS ycfS ynhG family protein
FY152_15990	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_16000	COG2094	Belongs to the DNA glycosylase MPG family
FY152_16010	COG1609	Transcriptional regulator
FY152_16015	COG1653	transport
FY152_16040	COG0673	inositol 2-dehydrogenase activity
FY152_16045	COG0602	queuosine metabolic process
FY152_16050	COG0720	synthase
FY152_16055	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY152_16060	COG0673	inositol 2-dehydrogenase activity
FY152_16075	COG0395	ABC-type sugar transport system, permease component
FY152_16080	COG1175	transmembrane transport
FY152_16100	COG0280	phosphate acetyltransferase
FY152_16100	COG0281	malic enzyme
FY152_16115	COG0765	amino acid transport
FY152_16120	COG1126	abc transporter atp-binding protein
FY152_16125	COG2079	MmgE PrpD family protein
FY152_16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_16155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY152_16165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY152_16170	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY152_16175	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_16180	COG1129	ABC transporter
FY152_16190	COG1473	amidohydrolase
FY152_16195	COG0747	negative chemotaxis
FY152_16215	COG0601	transmembrane transport
FY152_16220	COG0583	DNA-binding transcription factor activity
FY152_16225	COG1446	asparaginase
FY152_16240	COG0747	negative chemotaxis
FY152_16260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_16265	COG0601	transmembrane transport
FY152_16270	COG2197	response regulator
FY152_16275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY152_16285	COG0673	inositol 2-dehydrogenase activity
FY152_16290	COG0673	inositol 2-dehydrogenase activity
FY152_16310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_16315	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY152_16335	COG1595	DNA-templated transcription, initiation
FY152_16340	COG1120	ATPase activity
FY152_16345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_16360	COG2226	methyltransferase
FY152_16370	COG1120	ATPase activity
FY152_16375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_16390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY152_16395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY152_16405	COG1012	belongs to the aldehyde dehydrogenase family
FY152_16410	COG0473	3-isopropylmalate dehydrogenase activity
FY152_16415	COG1012	belongs to the aldehyde dehydrogenase family
FY152_16420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_16455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_16460	COG4172	Belongs to the ABC transporter superfamily
FY152_16465	COG1522	sequence-specific DNA binding
FY152_16470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_16480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_16485	COG1126	abc transporter atp-binding protein
FY152_16495	COG1473	amidohydrolase
FY152_16500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16510	COG1959	2 iron, 2 sulfur cluster binding
FY152_16520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY152_16525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16555	COG1960	acyl-CoA dehydrogenase activity
FY152_16580	COG0444	Belongs to the ABC transporter superfamily
FY152_16590	COG0667	Aldo Keto reductase
FY152_16600	COG0583	DNA-binding transcription factor activity
FY152_16605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16625	COG0747	negative chemotaxis
FY152_16630	COG1473	amidohydrolase
FY152_16635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16640	COG0702	epimerase
FY152_16650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_16675	COG4608	Belongs to the ABC transporter superfamily
FY152_16680	COG0444	Belongs to the ABC transporter superfamily
FY152_16690	COG0601	transmembrane transport
FY152_16700	COG2186	Transcriptional regulator
FY152_16715	COG0300	oxidoreductase activity
FY152_16725	COG3453	Protein conserved in bacteria
FY152_16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY152_16730	COG0640	Transcriptional regulator
FY152_16740	COG2391	methyltransferase activity
FY152_16745	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY152_16755	COG0022	dehydrogenase e1 component
FY152_16765	COG1960	acyl-CoA dehydrogenase activity
FY152_16770	COG0183	Belongs to the thiolase family
FY152_16780	COG1960	acyl-CoA dehydrogenase activity
FY152_16785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY152_16800	COG1024	Enoyl-CoA hydratase
FY152_16805	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY152_16810	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY152_16815	COG4952	isomerase
FY152_16820	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_16820	COG3347	Dehydrogenase
FY152_16825	COG1349	DNA-binding transcription factor activity
FY152_16835	COG1129	ABC transporter
FY152_16840	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_16850	COG3254	rhamnose metabolic process
FY152_16865	COG2264	protein methyltransferase activity
FY152_16870	COG5001	Diguanylate cyclase
FY152_16890	COG4335	DNA alkylation repair
FY152_16895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY152_16900	COG4208	sulfate ABC transporter
FY152_16910	COG4150	thiosulfate binding
FY152_16915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY152_16930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY152_16940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY152_16950	COG1040	competence protein
FY152_16955	COG2226	methyltransferase
FY152_16970	COG0494	nUDIX hydrolase
FY152_16980	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY152_16985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY152_16990	COG0653	protein targeting
FY152_16995	COG0697	spore germination
FY152_17065	COG2244	polysaccharide biosynthetic process
FY152_17085	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY152_17115	COG0438	transferase activity, transferring glycosyl groups
FY152_17120	COG0438	transferase activity, transferring glycosyl groups
FY152_17135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY152_17140	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY152_17140	COG2273	Hydrolase Family 16
FY152_17155	COG3842	ATPase activity
FY152_17160	COG3833	ABC-type maltose transport systems, permease component
FY152_17215	COG1396	sequence-specific DNA binding
FY152_17225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY152_17230	COG1129	ABC transporter
FY152_17235	COG4214	carbohydrate transport
FY152_17240	COG4213	ABC transporter substrate-binding protein
FY152_17255	COG0346	lactoylglutathione lyase activity
FY152_17260	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY152_17260	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY152_17265	COG4770	biotin carboxylase activity
FY152_17280	COG0625	glutathione transferase activity
FY152_17285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY152_17290	COG1396	sequence-specific DNA binding
FY152_17290	COG3800	Transcriptional regulator
FY152_17300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY152_17310	COG0300	oxidoreductase activity
FY152_17320	COG2096	Adenosyltransferase
FY152_17330	COG2086	electron transfer activity
FY152_17340	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY152_17345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY152_17350	COG0165	Argininosuccinate lyase
FY152_17385	COG2884	Cell division ATP-binding protein ftsE
FY152_17405	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY152_17415	COG0287	Prephenate dehydrogenase
FY152_17420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY152_17425	COG2226	methyltransferase
FY152_17430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY152_17445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY152_17450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY152_17485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY152_17490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY152_17500	COG4974	Belongs to the 'phage' integrase family
FY152_17505	COG0825	malonyl-CoA metabolic process
FY152_17510	COG3034	peptidoglycan biosynthetic process
FY152_17515	COG0425	Belongs to the sulfur carrier protein TusA family
FY152_17515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY152_17520	COG0523	cobalamin synthesis protein
FY152_17525	COG1686	Belongs to the peptidase S11 family
FY152_17530	COG1473	amidohydrolase
FY152_17560	COG0758	DNA mediated transformation
FY152_17565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY152_17605	COG2755	lipolytic protein G-D-S-L family
FY152_17605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY152_17765	COG0175	sulfate reduction
FY152_17915	COG4953	penicillin-binding protein 1C
FY152_17920	COG2373	Large extracellular alpha-helical protein
FY152_17925	COG2835	tetraacyldisaccharide 4'-kinase activity
FY152_17935	COG3118	belongs to the thioredoxin family
FY152_17955	COG0482	sulfurtransferase activity
FY152_17970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY152_17985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY152_17990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY152_17995	COG0037	tRNA processing
FY152_18005	COG2885	chlorophyll binding
FY152_18010	COG0823	Involved in the tonB-independent uptake of proteins
FY152_18030	COG0824	Thioesterase
FY152_18040	COG0494	nUDIX hydrolase
FY152_18055	COG2255	four-way junction helicase activity
FY152_18060	COG0632	four-way junction helicase activity
FY152_18065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY152_18070	COG0840	transmembrane signaling receptor activity
FY152_18075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_18080	COG0217	transcriptional regulatory protein
FY152_18095	COG1692	metallophosphoesterase
FY152_18105	COG1253	flavin adenine dinucleotide binding
FY152_18145	COG0126	phosphoglycerate kinase activity
FY152_18150	COG3588	fructose-bisphosphate aldolase
FY152_18170	COG0254	rRNA binding
FY152_18175	COG1132	(ABC) transporter
FY152_18195	COG0483	inositol monophosphate 1-phosphatase activity
FY152_18225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY152_18230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY152_18235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY152_18240	COG0457	Tetratricopeptide repeat
FY152_18245	COG3750	Belongs to the UPF0335 family
FY152_18265	COG0469	pyruvate kinase activity
FY152_18270	COG3108	Peptidase M15
FY152_18275	COG2204	response regulator
FY152_18280	COG1164	Oligoendopeptidase f
FY152_18285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY152_18295	COG5310	Homospermidine synthase
FY152_18305	COG0737	Belongs to the 5'-nucleotidase family
FY152_18310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY152_18315	COG0330	HflC and HflK could
FY152_18340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY152_18345	COG2951	lytic endotransglycosylase activity
FY152_18375	COG0067	glutamate synthase
FY152_18375	COG0070	glutamate synthase
FY152_18375	COG0069	glutamate synthase activity
FY152_18390	COG2205	protein histidine kinase activity
FY152_18395	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY152_18400	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY152_18405	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY152_18415	COG0252	asparaginase activity
FY152_18425	COG1027	Aspartate ammonia-lyase
FY152_18430	COG2186	Transcriptional regulator
FY152_18455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_18465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_18475	COG0747	negative chemotaxis
FY152_18480	COG0747	negative chemotaxis
FY152_18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_18505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY152_18525	COG0778	Nitroreductase
FY152_18530	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_18535	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_18545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_18550	COG0601	transmembrane transport
FY152_18555	COG0747	negative chemotaxis
FY152_18560	COG1802	Transcriptional regulator
FY152_18580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_18585	COG4172	Belongs to the ABC transporter superfamily
FY152_18590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_18595	COG0601	transmembrane transport
FY152_18600	COG0747	negative chemotaxis
FY152_18610	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY152_18615	COG1454	alcohol dehydrogenase
FY152_18660	COG2307	Protein conserved in bacteria
FY152_18660	COG2308	Evidence 4 Homologs of previously reported genes of
FY152_18675	COG0488	(ABC) transporter
FY152_18680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY152_18715	COG1063	alcohol dehydrogenase
FY152_18720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY152_18725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_18735	COG0765	amino acid transport
FY152_18740	COG0765	amino acid transport
FY152_18745	COG4221	oxidoreductase activity
FY152_18750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY152_18755	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_18760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY152_18775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY152_18790	COG0697	spore germination
FY152_18795	COG0697	spore germination
FY152_18800	COG0511	ligase activity, forming carbon-carbon bonds
FY152_18805	COG0439	Biotin carboxylase
FY152_18815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY152_18820	COG1984	allophanate hydrolase subunit 2
FY152_18825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY152_18830	COG3842	ATPase activity
FY152_18840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY152_18850	COG0436	Aminotransferase
FY152_18855	COG4221	oxidoreductase activity
FY152_18865	COG1070	Carbohydrate kinase
FY152_18875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY152_18880	COG0667	Aldo Keto reductase
FY152_18890	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_18895	COG1129	ABC transporter
FY152_18900	COG1879	ABC-type sugar transport system periplasmic component
FY152_18930	COG0071	Belongs to the small heat shock protein (HSP20) family
FY152_18945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY152_18960	COG0395	ABC-type sugar transport system, permease component
FY152_18975	COG3842	ATPase activity
FY152_18990	COG1648	precorrin-2 dehydrogenase activity
FY152_18990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY152_18995	COG0243	molybdopterin cofactor binding
FY152_19005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY152_19010	COG1116	anion transmembrane transporter activity
FY152_19015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_19020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY152_19030	COG3707	response regulator
FY152_19035	COG1802	Transcriptional regulator
FY152_19040	COG1914	H( )-stimulated, divalent metal cation uptake system
FY152_19045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY152_19050	COG4336	lyase activity
FY152_19055	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY152_19060	COG4770	biotin carboxylase activity
FY152_19070	COG0789	Transcriptional regulator
FY152_19075	COG4771	TonB-dependent receptor
FY152_19080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY152_19100	COG1414	Transcriptional regulator
FY152_19105	COG1475	DNA binding
FY152_19110	COG1192	Involved in chromosome partitioning
FY152_19140	COG0596	Alpha beta hydrolase
FY152_19145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY152_19155	COG2986	histidine ammonia-lyase
FY152_19160	COG1228	amidohydrolase
FY152_19165	COG0402	S-adenosylhomocysteine deaminase activity
FY152_19225	COG3842	ATPase activity
FY152_19230	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_19235	COG1177	transmembrane transport
FY152_19250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY152_19260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY152_19275	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_19280	COG0583	DNA-binding transcription factor activity
FY152_19285	COG4178	(ABC) transporter
FY152_19295	COG0583	DNA-binding transcription factor activity
FY152_19300	COG3585	molybdate ion transport
FY152_19305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY152_19315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY152_19320	COG1956	GAF domain-containing protein
FY152_19330	COG0604	alcohol dehydrogenase
FY152_19335	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_19345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY152_19355	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_19365	COG1653	transport
FY152_19370	COG0395	ABC-type sugar transport system, permease component
FY152_19375	COG4209	transmembrane transport
FY152_19380	COG3842	ATPase activity
FY152_19385	COG1802	Transcriptional regulator
FY152_19395	COG0583	DNA-binding transcription factor activity
FY152_19400	COG0583	DNA-binding transcription factor activity
FY152_19405	COG0346	lactoylglutathione lyase activity
FY152_19420	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY152_19450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY152_19465	COG0356	it plays a direct role in the translocation of protons across the membrane
FY152_19470	COG0387	Pfam Sodium calcium exchanger
FY152_19480	COG2212	antiporter activity
FY152_19485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY152_19490	COG0583	DNA-binding transcription factor activity
FY152_19495	COG0477	Major facilitator Superfamily
FY152_19505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_19515	COG4172	Belongs to the ABC transporter superfamily
FY152_19520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_19525	COG0601	transmembrane transport
FY152_19540	COG0277	FAD linked oxidase domain protein
FY152_19605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY152_19615	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY152_19620	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY152_19625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY152_19645	COG0010	Belongs to the arginase family
FY152_19655	COG0697	spore germination
FY152_19660	COG0673	inositol 2-dehydrogenase activity
FY152_19690	COG0477	Major facilitator Superfamily
FY152_19705	COG2194	sulfuric ester hydrolase activity
FY152_19715	COG0583	DNA-binding transcription factor activity
FY152_19720	COG4774	siderophore transport
FY152_19735	COG1120	ATPase activity
FY152_19745	COG3474	cytochrome
FY152_19750	COG2137	regulation of response to DNA damage stimulus
FY152_19755	COG3386	PFAM SMP-30 Gluconolaconase
FY152_19765	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_19770	COG1129	ABC transporter
FY152_19775	COG1879	ABC-type sugar transport system periplasmic component
FY152_19780	COG4585	Histidine kinase
FY152_19785	COG2197	response regulator
FY152_19795	COG2133	pyrroloquinoline quinone binding
FY152_19805	COG0500	methyltransferase
FY152_19810	COG0564	pseudouridine synthase activity
FY152_19830	COG4176	ABC-type proline glycine betaine transport system permease component
FY152_19845	COG4191	Histidine kinase
FY152_19845	COG0784	Response regulator, receiver
FY152_19855	COG0489	protein tyrosine kinase activity
FY152_19855	COG3206	protein involved in exopolysaccharide biosynthesis
FY152_19860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY152_19865	COG1215	transferase activity, transferring glycosyl groups
FY152_19870	COG1215	transferase activity, transferring glycosyl groups
FY152_19875	COG1215	transferase activity, transferring glycosyl groups
FY152_19880	COG0438	transferase activity, transferring glycosyl groups
FY152_19885	COG2273	Hydrolase Family 16
FY152_19890	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY152_19895	COG2244	polysaccharide biosynthetic process
FY152_19900	COG0463	Glycosyl transferase, family 2
FY152_19905	COG2327	Polysaccharide pyruvyl transferase
FY152_19910	COG1215	transferase activity, transferring glycosyl groups
FY152_19930	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY152_19935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_19950	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY152_19950	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY152_19975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_19985	COG1523	belongs to the glycosyl hydrolase 13 family
FY152_19990	COG0033	Phosphoglucomutase
FY152_19995	COG0297	glycogen (starch) synthase activity
FY152_20000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY152_20005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY152_20010	COG0058	SHG alpha-glucan phosphorylase activity
FY152_20020	COG1794	racemase activity, acting on amino acids and derivatives
FY152_20025	COG1522	sequence-specific DNA binding
FY152_20035	COG2084	Dehydrogenase
FY152_20040	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_20045	COG1063	alcohol dehydrogenase
FY152_20055	COG4988	ABC transporter
FY152_20060	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY152_20070	COG1294	oxidase, subunit
FY152_20100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY152_20105	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY152_20140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY152_20145	COG0539	negative regulation of cytoplasmic translation
FY152_20175	COG4221	oxidoreductase activity
FY152_20180	COG0006	proline dipeptidase activity
FY152_20185	COG0747	negative chemotaxis
FY152_20190	COG0601	transmembrane transport
FY152_20195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_20200	COG0444	Belongs to the ABC transporter superfamily
FY152_20205	COG4608	Belongs to the ABC transporter superfamily
FY152_20210	COG0246	Mannitol dehydrogenase
FY152_20225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_20270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY152_20275	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_20290	COG4993	Dehydrogenase
FY152_20295	COG3685	Protein conserved in bacteria
FY152_20300	COG1285	pathogenesis
FY152_20305	COG0562	UDP-galactopyranose mutase
FY152_20325	COG0693	protein deglycase activity
FY152_20345	COG0189	ligase activity
FY152_20350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY152_20355	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY152_20365	COG0435	Glutathione S-transferase
FY152_20370	COG0583	DNA-binding transcription factor activity
FY152_20375	COG1012	belongs to the aldehyde dehydrogenase family
FY152_20380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY152_20385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_20390	COG1116	anion transmembrane transporter activity
FY152_20400	COG1522	sequence-specific DNA binding
FY152_20415	COG0784	Response regulator, receiver
FY152_20425	COG3920	Histidine kinase
FY152_20435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY152_20455	COG0019	diaminopimelate decarboxylase activity
FY152_20470	COG0527	aspartate kinase activity
FY152_20480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY152_20485	COG2890	protein-(glutamine-N5) methyltransferase activity
FY152_20495	COG0542	response to heat
FY152_20500	COG0739	heme binding
FY152_20500	COG0741	lytic transglycosylase activity
FY152_20500	COG1196	nuclear chromosome segregation
FY152_20540	COG2860	membrane
FY152_20560	COG2200	EAL domain
FY152_20570	COG2271	Major facilitator Superfamily
FY152_20625	COG1278	Cold shock
FY152_20695	COG2207	Transcriptional regulator
FY152_20725	COG0583	DNA-binding transcription factor activity
FY152_20735	COG1733	regulation of RNA biosynthetic process
FY152_20750	COG0745	RESPONSE REGULATOR receiver
FY152_20760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_20765	COG1136	(ABC) transporter
FY152_20765	COG0577	efflux transmembrane transporter activity
FY152_20775	COG1733	regulation of RNA biosynthetic process
FY152_20815	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_20820	COG3842	ATPase activity
FY152_20825	COG0483	inositol monophosphate 1-phosphatase activity
FY152_20835	COG1473	amidohydrolase
FY152_20845	COG4172	Belongs to the ABC transporter superfamily
FY152_20860	COG4166	transmembrane transport
FY152_20875	COG1733	regulation of RNA biosynthetic process
FY152_20895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY152_20910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY152_20920	COG2986	histidine ammonia-lyase
FY152_20925	COG4172	Belongs to the ABC transporter superfamily
FY152_20930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_20935	COG0601	transmembrane transport
FY152_20940	COG4166	transmembrane transport
FY152_20960	COG0584	glycerophosphoryl diester phosphodiesterase
FY152_20965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_20975	COG4608	Belongs to the ABC transporter superfamily
FY152_20980	COG0444	Belongs to the ABC transporter superfamily
FY152_20995	COG1846	Transcriptional regulator
FY152_20995	COG1940	carbohydrate kinase activity
FY152_21015	COG1069	ribulokinase activity
FY152_21020	COG1349	DNA-binding transcription factor activity
FY152_21025	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_21050	COG0395	ABC-type sugar transport system, permease component
FY152_21060	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_21090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY152_21095	COG1349	DNA-binding transcription factor activity
FY152_21100	COG4608	Belongs to the ABC transporter superfamily
FY152_21110	COG0601	transmembrane transport
FY152_21115	COG0747	negative chemotaxis
FY152_21125	COG1063	alcohol dehydrogenase
FY152_21130	COG3284	Transcriptional regulator
FY152_21150	COG1129	ABC transporter
FY152_21155	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_21160	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_21175	COG1082	Xylose isomerase domain protein TIM barrel
FY152_21185	COG1126	abc transporter atp-binding protein
FY152_21190	COG0765	amino acid transport
FY152_21195	COG0765	amino acid transport
FY152_21200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_21205	COG3608	succinylglutamate desuccinylase aspartoacylase
FY152_21210	COG0006	proline dipeptidase activity
FY152_21215	COG2423	ornithine cyclodeaminase activity
FY152_21220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY152_21225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY152_21230	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY152_21235	COG1012	belongs to the aldehyde dehydrogenase family
FY152_21240	COG1522	sequence-specific DNA binding
FY152_21260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY152_21265	COG2986	histidine ammonia-lyase
FY152_21270	COG4175	Glycine betaine
FY152_21270	COG0517	IMP dehydrogenase activity
FY152_21275	COG4176	ABC-type proline glycine betaine transport system permease component
FY152_21295	COG0583	DNA-binding transcription factor activity
FY152_21300	COG2986	histidine ammonia-lyase
FY152_21310	COG1129	ABC transporter
FY152_21320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_21325	COG1070	Carbohydrate kinase
FY152_21340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY152_21350	COG0183	Belongs to the thiolase family
FY152_21355	COG3396	Phenylacetate-CoA oxygenase
FY152_21360	COG3460	Phenylacetate-CoA oxygenase
FY152_21365	COG3396	Phenylacetate-CoA oxygenase
FY152_21370	COG2151	metal-sulfur cluster biosynthetic enzyme
FY152_21375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY152_21385	COG1012	belongs to the aldehyde dehydrogenase family
FY152_21385	COG2030	dehydratase
FY152_21390	COG1309	transcriptional regulator
FY152_21400	COG2050	protein possibly involved in aromatic compounds catabolism
FY152_21405	COG1024	Enoyl-CoA hydratase
FY152_21410	COG1012	belongs to the aldehyde dehydrogenase family
FY152_21420	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY152_21440	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY152_21440	COG1024	Enoyl-CoA hydratase
FY152_21455	COG1120	ATPase activity
FY152_21460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_21465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_21470	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY152_21475	COG4772	TonB-dependent receptor
FY152_21505	COG0395	ABC-type sugar transport system, permease component
FY152_21510	COG3842	ATPase activity
FY152_21525	COG1175	transmembrane transport
FY152_21545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY152_21550	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_21580	COG0840	transmembrane signaling receptor activity
FY152_21590	COG2267	carboxylic ester hydrolase activity
FY152_21600	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY152_21605	COG0583	DNA-binding transcription factor activity
FY152_21610	COG2814	Major facilitator Superfamily
FY152_21635	COG1802	Transcriptional regulator
FY152_21660	COG3938	Belongs to the proline racemase family
FY152_21675	COG0765	amino acid transport
FY152_21690	COG3938	Belongs to the proline racemase family
FY152_21700	COG3958	Transketolase
FY152_21705	COG3959	Transketolase, thiamine diphosphate binding domain
FY152_21715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY152_21725	COG0583	DNA-binding transcription factor activity
FY152_21735	COG0583	DNA-binding transcription factor activity
FY152_21740	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_21745	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_21750	COG4213	ABC transporter substrate-binding protein
FY152_21755	COG1129	ABC transporter
FY152_21760	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_21765	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_21780	COG1063	alcohol dehydrogenase
FY152_21790	COG0371	Dehydrogenase
FY152_21795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY152_21800	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_21805	COG1129	ABC transporter
FY152_21815	COG3958	Transketolase
FY152_21820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FY152_21825	COG1012	belongs to the aldehyde dehydrogenase family
FY152_21830	COG1802	Transcriptional regulator
FY152_21845	COG1120	ATPase activity
FY152_21855	COG4774	siderophore transport
FY152_21870	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY152_21880	COG0367	asparagine synthase
FY152_21890	COG0318	PFAM AMP-dependent synthetase and ligase
FY152_21895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY152_21950	COG4702	Belongs to the UPF0303 family
FY152_21960	COG0673	inositol 2-dehydrogenase activity
FY152_21970	COG1024	Enoyl-CoA hydratase
FY152_21975	COG1012	belongs to the aldehyde dehydrogenase family
FY152_21980	COG1653	transport
FY152_21985	COG1175	transmembrane transport
FY152_21990	COG0395	ABC-type sugar transport system, permease component
FY152_21995	COG3842	ATPase activity
FY152_22010	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY152_22015	COG2376	Dihydroxyacetone kinase
FY152_22020	COG2271	Major facilitator Superfamily
FY152_22025	COG1309	transcriptional regulator
FY152_22045	COG4608	Belongs to the ABC transporter superfamily
FY152_22050	COG0444	Belongs to the ABC transporter superfamily
FY152_22055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_22060	COG0601	transmembrane transport
FY152_22065	COG0747	negative chemotaxis
FY152_22085	COG0765	amino acid transport
FY152_22090	COG4597	amino acid ABC transporter
FY152_22095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_22105	COG0747	negative chemotaxis
FY152_22110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_22115	COG1957	nucleoside hydrolase
FY152_22125	COG0601	transmembrane transport
FY152_22130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_22145	COG1063	alcohol dehydrogenase
FY152_22155	COG1879	ABC-type sugar transport system periplasmic component
FY152_22165	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_22215	COG1178	ABC-type Fe3 transport system permease component
FY152_22220	COG3842	ATPase activity
FY152_22250	COG1253	flavin adenine dinucleotide binding
FY152_22275	COG2423	ornithine cyclodeaminase activity
FY152_22280	COG0251	oxidation-reduction process
FY152_22285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY152_22290	COG0477	Major facilitator Superfamily
FY152_22300	COG0583	DNA-binding transcription factor activity
FY152_22305	COG0668	transmembrane transport
FY152_22325	COG1879	ABC-type sugar transport system periplasmic component
FY152_22330	COG1129	ABC transporter
FY152_22335	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_22340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_22345	COG1609	Transcriptional regulator
FY152_22355	COG0673	inositol 2-dehydrogenase activity
FY152_22380	COG3189	MarR family transcriptional regulator
FY152_22395	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_22400	COG1535	isochorismatase
FY152_22400	COG3433	isochorismatase activity
FY152_22405	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY152_22410	COG1169	isochorismate synthase
FY152_22420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY152_22420	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY152_22425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY152_22435	COG2375	cellular response to nickel ion
FY152_22445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_22450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_22455	COG1120	ATPase activity
FY152_22460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_22470	COG4774	siderophore transport
FY152_22470	COG1629	transport
FY152_22475	COG1960	acyl-CoA dehydrogenase activity
FY152_22480	COG0583	DNA-binding transcription factor activity
FY152_22485	COG1609	Transcriptional regulator
FY152_22495	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_22505	COG3842	ATPase activity
FY152_22515	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY152_22530	COG1473	amidohydrolase
FY152_22545	COG0747	negative chemotaxis
FY152_22550	COG0601	transmembrane transport
FY152_22555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_22560	COG0444	Belongs to the ABC transporter superfamily
FY152_22565	COG4608	Belongs to the ABC transporter superfamily
FY152_22570	COG0583	DNA-binding transcription factor activity
FY152_22575	COG0747	negative chemotaxis
FY152_22585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_22590	COG0154	amidase activity
FY152_22595	COG0693	protein deglycase activity
FY152_22605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_22610	COG0601	transmembrane transport
FY152_22620	COG1473	amidohydrolase
FY152_22625	COG4172	Belongs to the ABC transporter superfamily
FY152_22630	COG2390	Transcriptional regulator
FY152_22640	COG1175	transmembrane transport
FY152_22645	COG0395	ABC-type sugar transport system, permease component
FY152_22670	COG1069	ribulokinase activity
FY152_22695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY152_22705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY152_22710	COG1414	Transcriptional regulator
FY152_22715	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_22725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY152_22730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY152_22735	COG1121	(ABC) transporter
FY152_22740	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY152_22750	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY152_22755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY152_22760	COG3273	potassium ion transport
FY152_22760	COG0471	metal ion transport
FY152_22765	COG2827	Endonuclease containing a URI domain
FY152_22770	COG1253	flavin adenine dinucleotide binding
FY152_22775	COG1309	transcriptional regulator
FY152_22790	COG1609	Transcriptional regulator
FY152_22795	COG1070	Carbohydrate kinase
FY152_22800	COG2115	Belongs to the xylose isomerase family
FY152_22810	COG0583	DNA-binding transcription factor activity
FY152_22840	COG3047	cAMP biosynthetic process
FY152_22855	COG3842	ATPase activity
FY152_22860	COG0395	ABC-type sugar transport system, permease component
FY152_22865	COG1175	transmembrane transport
FY152_22870	COG1653	transport
FY152_22875	COG0523	cobalamin synthesis protein
FY152_22890	COG0523	cobalamin synthesis protein
FY152_22895	COG1121	(ABC) transporter
FY152_22905	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY152_22920	COG0626	cystathionine gamma-synthase activity
FY152_22925	COG2182	Extracellular solute-binding protein
FY152_22930	COG1175	transmembrane transport
FY152_22935	COG0395	ABC-type sugar transport system, permease component
FY152_22950	COG0395	ABC-type sugar transport system, permease component
FY152_22955	COG1175	transmembrane transport
FY152_22960	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY152_22965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY152_22975	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_22980	COG1063	alcohol dehydrogenase
FY152_22985	COG1609	Transcriptional regulator
FY152_23000	COG2084	Dehydrogenase
FY152_23005	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY152_23015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY152_23020	COG0583	DNA-binding transcription factor activity
FY152_23025	COG2223	nitrite transmembrane transporter activity
FY152_23030	COG4977	sequence-specific DNA binding
FY152_23075	COG2186	Transcriptional regulator
FY152_23080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY152_23085	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY152_23090	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_23095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY152_23100	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_23105	COG3618	amidohydrolase
FY152_23110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY152_23125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY152_23130	COG1629	transport
FY152_23165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY152_23170	COG0577	efflux transmembrane transporter activity
FY152_23170	COG1136	(ABC) transporter
FY152_23175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY152_23205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY152_23215	COG1278	Cold shock
FY152_23220	COG0673	inositol 2-dehydrogenase activity
FY152_23235	COG0673	inositol 2-dehydrogenase activity
FY152_23240	COG1309	transcriptional regulator
FY152_23245	COG1653	transport
FY152_23250	COG1175	transmembrane transport
FY152_23255	COG0395	ABC-type sugar transport system, permease component
FY152_23260	COG3842	ATPase activity
FY152_23275	COG1082	Xylose isomerase domain protein TIM barrel
FY152_23280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY152_23290	COG1609	Transcriptional regulator
FY152_23320	COG3842	ATPase activity
FY152_23330	COG1177	transmembrane transport
FY152_23335	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_23360	COG3842	ATPase activity
FY152_23365	COG0395	ABC-type sugar transport system, permease component
FY152_23370	COG1175	transmembrane transport
FY152_23375	COG1653	transport
FY152_23405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FY152_23430	COG3842	ATPase activity
FY152_23445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY152_23450	COG1472	Belongs to the glycosyl hydrolase 3 family
FY152_23455	COG0583	DNA-binding transcription factor activity
FY152_23460	COG2072	flavoprotein involved in K transport
FY152_23475	COG3842	ATPase activity
FY152_23485	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_23490	COG0395	ABC-type sugar transport system, permease component
FY152_23540	COG2233	PERMEase
FY152_23550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_23555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY152_23580	COG1522	sequence-specific DNA binding
FY152_23585	COG4106	trans-aconitate 2-methyltransferase activity
FY152_23625	COG1192	Involved in chromosome partitioning
FY152_23630	COG1475	DNA binding
FY152_23635	COG0640	Transcriptional regulator
FY152_23650	COG1126	abc transporter atp-binding protein
FY152_23655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY152_23660	COG1609	Transcriptional regulator
FY152_23695	COG3239	Fatty acid desaturase
FY152_23705	COG1278	Cold shock
FY152_23785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY152_23785	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY152_23815	COG4191	Histidine kinase
FY152_23820	COG1132	(ABC) transporter
FY152_23830	COG0640	Transcriptional regulator
FY152_23860	COG4977	sequence-specific DNA binding
FY152_23865	COG2211	Major facilitator Superfamily
FY152_23870	COG2807	transmembrane transport
FY152_23875	COG1846	Transcriptional regulator
FY152_23890	COG2814	Major facilitator Superfamily
FY152_23920	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY152_23935	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY152_23940	COG0583	DNA-binding transcription factor activity
FY152_23955	COG0071	Belongs to the small heat shock protein (HSP20) family
FY152_24000	COG3838	Conjugal transfer protein Trbc
FY152_24005	COG3702	type iv secretory pathway
FY152_24010	COG3451	type IV secretory pathway VirB4
FY152_24025	COG3704	protein secretion by the type IV secretion system
FY152_24035	COG3736	Type IV secretory pathway, component VirB8
FY152_24040	COG3504	Conjugal transfer protein
FY152_24045	COG2948	multi-organism process
FY152_24050	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY152_24150	COG3831	ATPase activity
FY152_24165	COG3505	Type IV secretory pathway VirD4
FY152_24190	COG0583	DNA-binding transcription factor activity
FY152_24230	COG0745	RESPONSE REGULATOR receiver
FY152_24270	COG3842	ATPase activity
FY152_24275	COG4208	sulfate ABC transporter
FY152_24280	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_24300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY152_24305	COG1942	4-Oxalocrotonate Tautomerase
FY152_24315	COG3971	2-oxopent-4-enoate hydratase activity
FY152_24325	COG1414	Transcriptional regulator
FY152_24335	COG1137	ATPase activity
FY152_24350	COG4177	L-phenylalanine transmembrane transporter activity
FY152_24370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY152_24375	COG1175	transmembrane transport
FY152_24380	COG0395	ABC-type sugar transport system, permease component
FY152_24390	COG0366	Alpha amylase catalytic
FY152_24395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY152_24400	COG1082	Xylose isomerase domain protein TIM barrel
FY152_24405	COG3842	ATPase activity
FY152_24415	COG1940	carbohydrate kinase activity
FY152_24420	COG0395	ABC-type sugar transport system, permease component
FY152_24430	COG2182	Extracellular solute-binding protein
FY152_24435	COG0673	inositol 2-dehydrogenase activity
FY152_24465	COG1126	abc transporter atp-binding protein
FY152_24470	COG0765	amino acid transport
FY152_24475	COG0765	amino acid transport
FY152_24485	COG4608	Belongs to the ABC transporter superfamily
FY152_24495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_24510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY152_24515	COG0583	DNA-binding transcription factor activity
FY152_24520	COG2423	ornithine cyclodeaminase activity
FY152_24530	COG1957	nucleoside hydrolase
FY152_24550	COG1335	isochorismatase
FY152_24555	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_24600	COG0583	DNA-binding transcription factor activity
FY152_24605	COG1902	pentaerythritol trinitrate reductase activity
FY152_24610	COG0583	DNA-binding transcription factor activity
FY152_24615	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_24625	COG1335	isochorismatase
FY152_24630	COG0583	DNA-binding transcription factor activity
FY152_24640	COG1695	Transcriptional regulator
FY152_24720	COG2207	Transcriptional regulator
FY152_24765	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_24780	COG1802	Transcriptional regulator
FY152_24785	COG3485	protocatechuate 3,4-dioxygenase
FY152_24790	COG3971	2-oxopent-4-enoate hydratase activity
FY152_24805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY152_24810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY152_24825	COG1063	alcohol dehydrogenase
FY152_24835	COG1960	acyl-CoA dehydrogenase activity
FY152_24840	COG1024	Enoyl-CoA hydratase
FY152_24850	COG1012	belongs to the aldehyde dehydrogenase family
FY152_24855	COG0477	Major facilitator Superfamily
FY152_24870	COG3706	GGDEF domain
FY152_24890	COG1846	Transcriptional regulator
FY152_24930	COG1012	belongs to the aldehyde dehydrogenase family
FY152_24940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY152_24950	COG3386	PFAM SMP-30 Gluconolaconase
FY152_24955	COG3622	Belongs to the hyi family
FY152_24960	COG2084	Dehydrogenase
FY152_24990	COG1940	carbohydrate kinase activity
FY152_24995	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_25005	COG1129	ABC transporter
FY152_25025	COG0583	DNA-binding transcription factor activity
FY152_25030	COG2271	Major facilitator Superfamily
FY152_25040	COG2272	Belongs to the type-B carboxylesterase lipase family
FY152_25060	COG1129	ABC transporter
FY152_25085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY152_25095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY152_25130	COG0583	DNA-binding transcription factor activity
FY152_25135	COG1414	Transcriptional regulator
FY152_25145	COG4948	Mandelate Racemase Muconate Lactonizing
FY152_25155	COG3842	ATPase activity
FY152_25160	COG1175	transmembrane transport
FY152_25165	COG0395	ABC-type sugar transport system, permease component
FY152_25175	COG0477	Major facilitator Superfamily
FY152_25210	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY152_25230	COG0747	negative chemotaxis
FY152_25240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_25255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_25265	COG4215	(ABC) transporter
FY152_25320	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY152_25325	COG0251	oxidation-reduction process
FY152_25330	COG3547	Transposase (IS116 IS110 IS902 family)
FY152_25365	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_25370	COG1335	isochorismatase
FY152_25380	COG1309	transcriptional regulator
FY152_25385	COG4604	ABC transporter, ATP-binding protein
FY152_25390	COG4605	iron ion homeostasis
FY152_25395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY152_25405	COG2132	Multicopper oxidase
FY152_25410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY152_25415	COG4771	TonB-dependent receptor
FY152_25450	COG1695	Transcriptional regulator
FY152_25485	COG2132	Multicopper oxidase
FY152_25520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY152_25540	COG1192	Involved in chromosome partitioning
FY152_25545	COG1475	DNA binding
FY152_25550	COG0640	Transcriptional regulator
FY152_25555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY152_25600	COG0583	DNA-binding transcription factor activity
FY152_25610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY152_25615	COG1116	anion transmembrane transporter activity
FY152_25620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY152_25630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_25635	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_25665	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY152_25670	COG1129	ABC transporter
FY152_25695	COG4172	Belongs to the ABC transporter superfamily
FY152_25700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_25705	COG0601	transmembrane transport
FY152_25715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_25720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY152_25725	COG0583	DNA-binding transcription factor activity
FY152_25735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY152_25750	COG1132	(ABC) transporter
FY152_25755	COG4172	Belongs to the ABC transporter superfamily
FY152_25760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_25780	COG1082	Xylose isomerase domain protein TIM barrel
FY152_25785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY152_25790	COG0019	diaminopimelate decarboxylase activity
FY152_25800	COG1475	DNA binding
FY152_25810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY152_25900	COG1475	DNA binding
FY152_25925	COG2824	Alkylphosphonate utilization operon protein PhnA
FY152_25975	COG5489	Protein of unknown function (DUF736)
FY152_26060	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY152_26075	COG0747	negative chemotaxis
FY152_26080	COG0444	Belongs to the ABC transporter superfamily
FY152_26095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_26100	COG0584	glycerophosphoryl diester phosphodiesterase
FY152_26105	COG0483	inositol monophosphate 1-phosphatase activity
FY152_26170	COG3161	chorismate lyase activity
FY152_26320	COG3436	PFAM IS66 Orf2 family protein
FY152_26400	COG2222	sugar isomerase
FY152_26410	COG0006	proline dipeptidase activity
FY152_26430	COG1177	transmembrane transport
FY152_26435	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY152_26440	COG3842	ATPase activity
FY152_26470	COG3842	ATPase activity
FY152_26475	COG0006	proline dipeptidase activity
FY152_26495	COG0300	oxidoreductase activity
FY152_26500	COG0129	dihydroxy-acid dehydratase activity
FY152_26505	COG0667	Aldo Keto reductase
FY152_26515	COG1028	Short-chain dehydrogenase reductase Sdr
FY152_26525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_26530	COG0601	transmembrane transport
FY152_26535	COG4172	Belongs to the ABC transporter superfamily
FY152_26545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY152_26580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY152_26615	COG3701	Conjugal transfer protein
FY152_26620	COG3846	protein secretion by the type IV secretion system
FY152_26630	COG5314	conjugation
FY152_26635	COG3451	type IV secretory pathway VirB4
FY152_26650	COG4962	Type ii secretion system protein e