locus-tag	class	description
FY153_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY153_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY153_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY153_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY153_00025	COG1420	regulation of RNA biosynthetic process
FY153_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY153_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY153_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY153_00050	COG1137	ATPase activity
FY153_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY153_00065	COG0616	signal peptide processing
FY153_00070	COG0776	regulation of translation
FY153_00080	COG0116	Belongs to the methyltransferase superfamily
FY153_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY153_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY153_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY153_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY153_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY153_00115	COG0728	peptidoglycan biosynthetic process
FY153_00125	COG0180	Tryptophanyl-tRNA synthetase
FY153_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY153_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY153_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY153_00165	COG1702	phosphate starvation-inducible protein PhoH
FY153_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY153_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY153_00185	COG1396	sequence-specific DNA binding
FY153_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY153_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY153_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_00210	COG0242	peptide deformylase activity
FY153_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY153_00220	COG0101	tRNA pseudouridine synthase activity
FY153_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY153_00235	COG2171	N-acyltransferase activity
FY153_00245	COG0840	transmembrane signaling receptor activity
FY153_00250	COG1957	nucleoside hydrolase
FY153_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY153_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY153_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY153_00295	COG0706	membrane insertase activity
FY153_00300	COG0594	ribonuclease P activity
FY153_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY153_00310	COG0840	transmembrane signaling receptor activity
FY153_00325	COG2226	methyltransferase
FY153_00330	COG3842	ATPase activity
FY153_00335	COG1175	transmembrane transport
FY153_00340	COG0395	ABC-type sugar transport system, permease component
FY153_00355	COG0427	acetyl-CoA hydrolase
FY153_00365	COG3938	Belongs to the proline racemase family
FY153_00370	COG0418	dihydroorotase activity
FY153_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY153_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY153_00400	COG0166	Belongs to the GPI family
FY153_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY153_00410	COG3842	ATPase activity
FY153_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY153_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY153_00425	COG4774	siderophore transport
FY153_00470	COG2326	polyphosphate kinase activity
FY153_00475	COG5002	protein histidine kinase activity
FY153_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY153_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY153_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY153_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY153_00505	COG0745	RESPONSE REGULATOR receiver
FY153_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY153_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY153_00530	COG2967	ApaG domain
FY153_00545	COG0717	Belongs to the dCTP deaminase family
FY153_00555	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY153_00560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY153_00610	COG0167	dihydroorotate dehydrogenase activity
FY153_00625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY153_00645	COG1959	2 iron, 2 sulfur cluster binding
FY153_00650	COG1201	RNA secondary structure unwinding
FY153_00680	COG1960	acyl-CoA dehydrogenase activity
FY153_00685	COG0183	Belongs to the thiolase family
FY153_00690	COG1024	Enoyl-CoA hydratase
FY153_00690	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY153_00710	COG1320	monovalent cation:proton antiporter activity
FY153_00715	COG2212	antiporter activity
FY153_00720	COG1863	multisubunit Na H antiporter MnhE subunit
FY153_00725	COG0651	ATP synthesis coupled electron transport
FY153_00730	COG1006	Multisubunit Na H antiporter MnhC subunit
FY153_00735	COG2111	Na H antiporter
FY153_00735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY153_00745	COG0840	transmembrane signaling receptor activity
FY153_00755	COG0745	RESPONSE REGULATOR receiver
FY153_00760	COG2198	Histidine kinase
FY153_00760	COG0643	Histidine kinase
FY153_00765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY153_00770	COG2201	protein-glutamate methylesterase activity
FY153_00775	COG0745	RESPONSE REGULATOR receiver
FY153_00780	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY153_00790	COG1766	The M ring may be actively involved in energy transduction
FY153_00795	COG2771	luxR family
FY153_00805	COG2972	Histidine kinase
FY153_00805	COG0840	transmembrane signaling receptor activity
FY153_00810	COG0784	Response regulator, receiver
FY153_00810	COG2198	Histidine kinase
FY153_00810	COG2205	protein histidine kinase activity
FY153_00815	COG1970	mechanosensitive ion channel activity
FY153_00820	COG0436	Aminotransferase
FY153_00835	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY153_00840	COG0424	maF-like protein
FY153_00845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY153_00855	COG5328	Belongs to the UPF0262 family
FY153_00860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY153_00870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY153_01135	COG3750	Belongs to the UPF0335 family
FY153_01170	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FY153_01190	COG0582	viral genome integration into host DNA
FY153_01205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY153_01215	COG1338	Plays a role in the flagellum-specific transport system
FY153_01225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY153_01235	COG1706	bacterial-type flagellum-dependent cell motility
FY153_01240	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY153_01245	COG4786	Flagellar basal body rod
FY153_01250	COG1677	Flagellar hook-basal body complex protein FliE
FY153_01255	COG1558	bacterial-type flagellum-dependent cell motility
FY153_01260	COG1815	bacterial-type flagellum-dependent cell motility
FY153_01270	COG1157	protein secretion by the type III secretion system
FY153_01275	COG4786	Flagellar basal body rod
FY153_01285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY153_01290	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY153_01295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY153_01300	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY153_01305	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY153_01330	COG1360	Flagellar Motor Protein
FY153_01355	COG1749	Flagellar hook protein flgE
FY153_01375	COG5443	negative regulation of bacterial-type flagellum assembly
FY153_01380	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY153_01390	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY153_01430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY153_01435	COG1609	Transcriptional regulator
FY153_01440	COG1653	transport
FY153_01445	COG1175	transmembrane transport
FY153_01450	COG0395	ABC-type sugar transport system, permease component
FY153_01455	COG0366	Alpha amylase catalytic
FY153_01460	COG3842	ATPase activity
FY153_01475	COG0129	dihydroxy-acid dehydratase activity
FY153_01480	COG0363	glucosamine-6-phosphate deaminase activity
FY153_01485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY153_01495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_01505	COG2081	HI0933 family
FY153_01525	COG2224	Isocitrate lyase
FY153_01540	COG3842	ATPase activity
FY153_01545	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_01550	COG1177	transmembrane transport
FY153_01560	COG2205	protein histidine kinase activity
FY153_01570	COG0248	Ppx GppA phosphatase
FY153_01575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY153_01580	COG0477	Major facilitator Superfamily
FY153_01610	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY153_01615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY153_01625	COG0142	geranyltranstransferase activity
FY153_01650	COG0752	glycyl-tRNA synthetase alpha subunit
FY153_01660	COG1704	LemA family
FY153_01665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY153_01675	COG0751	glycine-tRNA ligase activity
FY153_01680	COG1683	Conserved Protein
FY153_01685	COG0840	transmembrane signaling receptor activity
FY153_01695	COG0151	Belongs to the GarS family
FY153_01700	COG2183	response to ionizing radiation
FY153_01705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY153_01715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY153_01730	COG0583	DNA-binding transcription factor activity
FY153_01750	COG0306	phosphate transporter
FY153_01760	COG0561	phosphatase activity
FY153_01765	COG0438	transferase activity, transferring glycosyl groups
FY153_01770	COG2186	Transcriptional regulator
FY153_01785	COG0583	DNA-binding transcription factor activity
FY153_01790	COG0277	FAD linked oxidase domain protein
FY153_01795	COG0277	FAD linked oxidase domain protein
FY153_01800	COG0247	lactate metabolic process
FY153_01810	COG1376	ErfK ybiS ycfS ynhG family protein
FY153_01815	COG2818	Glycosylase
FY153_01825	COG2855	membrane
FY153_01830	COG0583	DNA-binding transcription factor activity
FY153_01860	COG0124	histidyl-tRNA synthetase
FY153_01870	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY153_01875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY153_01880	COG2259	Doxx family
FY153_01890	COG0459	protein refolding
FY153_01895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY153_01905	COG0196	riboflavin kinase activity
FY153_01910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY153_01920	COG0590	tRNA wobble adenosine to inosine editing
FY153_01925	COG1187	pseudouridine synthase activity
FY153_01930	COG0742	ribosomal rna small subunit methyltransferase
FY153_01935	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY153_01945	COG0312	modulator of DNA gyrase
FY153_01950	COG0483	inositol monophosphate 1-phosphatase activity
FY153_01960	COG1519	Transferase
FY153_01970	COG1663	tetraacyldisaccharide 4'-kinase activity
FY153_01980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY153_01985	COG0745	RESPONSE REGULATOR receiver
FY153_01990	COG5001	Diguanylate cyclase
FY153_01990	COG3300	MHYT domain
FY153_01995	COG3386	PFAM SMP-30 Gluconolaconase
FY153_02000	COG0800	Aldolase
FY153_02005	COG3734	2-keto-3-deoxy-galactonokinase
FY153_02010	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_02015	COG1414	Transcriptional regulator
FY153_02020	COG2197	response regulator
FY153_02035	COG0598	Magnesium transport protein CorA
FY153_02040	COG3158	transport of potassium into the cell
FY153_02055	COG0356	it plays a direct role in the translocation of protons across the membrane
FY153_02065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY153_02070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY153_02085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY153_02105	COG0009	L-threonylcarbamoyladenylate synthase
FY153_02115	COG4638	Rieske (2fe-2S)
FY153_02140	COG1960	acyl-CoA dehydrogenase activity
FY153_02155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY153_02160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY153_02165	COG0840	transmembrane signaling receptor activity
FY153_02175	COG1522	sequence-specific DNA binding
FY153_02200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY153_02205	COG1741	Belongs to the pirin family
FY153_02210	COG1722	exodeoxyribonuclease VII activity
FY153_02215	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY153_02220	COG1268	BioY protein
FY153_02225	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY153_02230	COG1122	ATPase activity
FY153_02235	COG3214	Protein conserved in bacteria
FY153_02240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY153_02240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY153_02245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY153_02260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY153_02275	COG0259	pyridoxamine-phosphate oxidase activity
FY153_02305	COG0312	modulator of DNA gyrase
FY153_02320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY153_02325	COG0109	protoheme IX farnesyltransferase activity
FY153_02330	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY153_02345	COG3346	SURF1 family
FY153_02350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY153_02355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY153_02360	COG0328	RNA-DNA hybrid ribonuclease activity
FY153_02370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY153_02370	COG0678	peroxiredoxin activity
FY153_02380	COG1678	Uncharacterized ACR, COG1678
FY153_02385	COG3237	CsbD-like
FY153_02395	COG3300	MHYT domain
FY153_02395	COG5001	Diguanylate cyclase
FY153_02400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY153_02405	COG0612	Peptidase, M16
FY153_02430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY153_02435	COG1802	Transcriptional regulator
FY153_02450	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY153_02455	COG3609	addiction module antidote protein, CC2985 family
FY153_02460	COG3668	Plasmid stabilization system
FY153_02470	COG1194	a g-specific adenine glycosylase
FY153_02485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY153_02490	COG1196	nuclear chromosome segregation
FY153_02495	COG2514	catechol 2,3-dioxygenase activity
FY153_02500	COG0574	Belongs to the PEP-utilizing enzyme family
FY153_02500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY153_02515	COG1823	symporter activity
FY153_02545	COG0579	oxidoreductase
FY153_02565	COG2895	sulfate adenylyltransferase (ATP) activity
FY153_02570	COG0175	sulfate reduction
FY153_02575	COG0175	sulfate reduction
FY153_02580	COG1959	2 iron, 2 sulfur cluster binding
FY153_02585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY153_02590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY153_02595	COG4208	sulfate ABC transporter
FY153_02600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY153_02610	COG2203	Gaf domain
FY153_02610	COG2200	EAL domain
FY153_02610	COG2199	diguanylate cyclase activity
FY153_02620	COG1309	transcriptional regulator
FY153_02625	COG1012	belongs to the aldehyde dehydrogenase family
FY153_02630	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY153_02660	COG0625	glutathione transferase activity
FY153_02670	COG0477	Major facilitator Superfamily
FY153_02680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY153_02680	COG1793	dna ligase
FY153_02700	COG1376	ErfK ybiS ycfS ynhG family protein
FY153_02705	COG1376	ErfK ybiS ycfS ynhG family protein
FY153_02710	COG1846	Transcriptional regulator
FY153_02715	COG1764	response to oxidative stress
FY153_02730	COG0488	(ABC) transporter
FY153_02765	COG4221	oxidoreductase activity
FY153_02780	COG0433	COG0433 Predicted ATPase
FY153_02790	COG1733	regulation of RNA biosynthetic process
FY153_02795	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY153_02810	COG0656	L-ascorbic acid biosynthetic process
FY153_02815	COG3781	membrane
FY153_02820	COG2378	regulation of single-species biofilm formation
FY153_02830	COG4106	trans-aconitate 2-methyltransferase activity
FY153_02835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY153_02840	COG0840	transmembrane signaling receptor activity
FY153_02845	COG0583	DNA-binding transcription factor activity
FY153_02860	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY153_02880	COG3909	cytochrome
FY153_02885	COG2010	Cytochrome c
FY153_02915	COG0789	Transcriptional regulator
FY153_02940	COG0517	IMP dehydrogenase activity
FY153_02940	COG4175	Glycine betaine
FY153_02945	COG4176	ABC-type proline glycine betaine transport system permease component
FY153_02970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_02980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY153_02980	COG2169	Transcriptional regulator
FY153_02990	COG2514	catechol 2,3-dioxygenase activity
FY153_03010	COG1272	protein, Hemolysin III
FY153_03020	COG1280	lysine exporter protein (LysE YggA)
FY153_03025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY153_03030	COG2111	Na H antiporter
FY153_03030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY153_03035	COG2111	Na H antiporter
FY153_03040	COG1006	Multisubunit Na H antiporter MnhC subunit
FY153_03045	COG0651	ATP synthesis coupled electron transport
FY153_03050	COG1863	multisubunit Na H antiporter MnhE subunit
FY153_03055	COG2212	antiporter activity
FY153_03060	COG1320	monovalent cation:proton antiporter activity
FY153_03065	COG4957	zinc ion binding
FY153_03080	COG2166	iron-sulfur cluster assembly
FY153_03090	COG2205	protein histidine kinase activity
FY153_03135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY153_03140	COG2983	Belongs to the UPF0260 family
FY153_03150	COG3041	Addiction module toxin RelE StbE family
FY153_03155	COG3077	Addiction module antitoxin, RelB DinJ family
FY153_03195	COG2814	Major facilitator Superfamily
FY153_03200	COG1621	beta-fructofuranosidase activity
FY153_03205	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY153_03255	COG4695	Portal protein
FY153_03360	COG4235	cytochrome complex assembly
FY153_03365	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY153_03370	COG1138	Cytochrome C-type biogenesis protein
FY153_03375	COG3088	subunit of a heme lyase
FY153_03380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY153_03385	COG0745	RESPONSE REGULATOR receiver
FY153_03395	COG3011	Protein conserved in bacteria
FY153_03400	COG3713	MltA-interacting MipA family protein
FY153_03405	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY153_03410	COG2205	protein histidine kinase activity
FY153_03410	COG2202	Pas domain
FY153_03420	COG0308	aminopeptidase N
FY153_03425	COG0697	spore germination
FY153_03440	COG0443	Heat shock 70 kDa protein
FY153_03475	COG0604	alcohol dehydrogenase
FY153_03480	COG1733	regulation of RNA biosynthetic process
FY153_03485	COG1968	undecaprenyl-diphosphatase activity
FY153_03490	COG2239	Acts as a magnesium transporter
FY153_03495	COG2814	Major facilitator Superfamily
FY153_03520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY153_03545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY153_03585	COG0741	lytic transglycosylase activity
FY153_03590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_03595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY153_03600	COG0840	transmembrane signaling receptor activity
FY153_03610	COG1758	RNA polymerase activity
FY153_03630	COG0736	holo-[acyl-carrier-protein] synthase activity
FY153_03635	COG0681	Belongs to the peptidase S26 family
FY153_03640	COG0571	ribonuclease III activity
FY153_03645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY153_03655	COG0784	Response regulator, receiver
FY153_03660	COG1381	Involved in DNA repair and RecF pathway recombination
FY153_03670	COG2226	methyltransferase
FY153_03680	COG1418	mRNA catabolic process
FY153_03690	COG0346	lactoylglutathione lyase activity
FY153_03705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_03710	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY153_03715	COG0668	transmembrane transport
FY153_03725	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY153_03755	COG1742	UPF0060 membrane protein
FY153_03770	COG1183	phosphatidylcholine synthase activity
FY153_03775	COG0688	phosphatidylethanolamine metabolic process
FY153_03780	COG5265	(ABC) transporter
FY153_03820	COG2852	Protein conserved in bacteria
FY153_03825	COG0215	cysteine-tRNA ligase activity
FY153_03830	COG4221	oxidoreductase activity
FY153_03835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY153_03840	COG1286	toxin biosynthetic process
FY153_03860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY153_03870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY153_03880	COG0305	Participates in initiation and elongation during chromosome replication
FY153_03900	COG0359	binds to the 23S rRNA
FY153_03910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY153_03915	COG0360	Binds together with S18 to 16S ribosomal RNA
FY153_03925	COG0667	Aldo Keto reductase
FY153_03930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY153_03940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY153_03945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY153_03955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY153_03960	COG1561	YicC-like family, N-terminal region
FY153_03965	COG0194	GDP metabolic process
FY153_03980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY153_03985	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY153_03995	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY153_04010	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY153_04030	COG4251	negative regulation of phosphorylation
FY153_04030	COG5001	Diguanylate cyclase
FY153_04030	COG2203	Gaf domain
FY153_04030	COG3706	GGDEF domain
FY153_04035	COG5001	Diguanylate cyclase
FY153_04035	COG3300	MHYT domain
FY153_04040	COG4191	Histidine kinase
FY153_04045	COG4566	intracellular signal transduction
FY153_04055	COG0488	(ABC) transporter
FY153_04060	COG3706	GGDEF domain
FY153_04070	COG0105	UTP biosynthetic process
FY153_04090	COG0314	molybdopterin synthase activity
FY153_04100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY153_04105	COG0322	excinuclease ABC activity
FY153_04110	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_04135	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY153_04140	COG0243	molybdopterin cofactor binding
FY153_04165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY153_04170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY153_04175	COG2226	methyltransferase
FY153_04180	COG0628	permease
FY153_04190	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY153_04195	COG0248	Ppx GppA phosphatase
FY153_04220	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY153_04230	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY153_04235	COG0477	Major facilitator Superfamily
FY153_04240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY153_04250	COG0840	transmembrane signaling receptor activity
FY153_04255	COG0659	secondary active sulfate transmembrane transporter activity
FY153_04265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY153_04270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY153_04280	COG0113	porphobilinogen synthase activity
FY153_04300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY153_04305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY153_04310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY153_04310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY153_04320	COG1280	lysine exporter protein (LysE YggA)
FY153_04325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY153_04330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY153_04335	COG2814	Major facilitator Superfamily
FY153_04340	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY153_04360	COG0416	fatty acid biosynthetic process
FY153_04365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY153_04370	COG0776	regulation of translation
FY153_04405	COG0601	transmembrane transport
FY153_04410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_04415	COG0444	Belongs to the ABC transporter superfamily
FY153_04425	COG0747	negative chemotaxis
FY153_04435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY153_04440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY153_04455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY153_04460	COG0583	DNA-binding transcription factor activity
FY153_04465	COG0737	Belongs to the 5'-nucleotidase family
FY153_04485	COG2897	thiosulfate sulfurtransferase activity
FY153_04500	COG0415	Belongs to the DNA photolyase family
FY153_04510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY153_04540	COG3932	Exopolysaccharide synthesis, ExoD
FY153_04545	COG1238	metal cluster binding
FY153_04620	COG1612	heme a metabolic process
FY153_04630	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY153_04635	COG0010	Belongs to the arginase family
FY153_04640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY153_04645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY153_04655	COG1832	CoA-binding protein
FY153_04680	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_04685	COG2124	cytochrome p450
FY153_04690	COG2199	diguanylate cyclase activity
FY153_04695	COG0740	serine-type endopeptidase activity
FY153_04700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY153_04705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY153_04715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY153_04740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY153_04745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY153_04750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY153_04760	COG0649	NAD binding
FY153_04770	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY153_04775	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY153_04785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY153_04790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY153_04800	COG0713	ATP synthesis coupled electron transport
FY153_04815	COG1007	ATP synthesis coupled electron transport
FY153_04820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY153_04820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY153_04835	COG0442	prolyl-tRNA aminoacylation
FY153_04845	COG1136	(ABC) transporter
FY153_04860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY153_04880	COG0784	Response regulator, receiver
FY153_04890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY153_04895	COG0477	Major facilitator Superfamily
FY153_04910	COG0557	exoribonuclease II activity
FY153_04915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY153_04925	COG0758	DNA mediated transformation
FY153_04930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY153_04940	COG0540	Belongs to the ATCase OTCase family
FY153_04955	COG1960	acyl-CoA dehydrogenase activity
FY153_04960	COG0456	acetyltransferase
FY153_04980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY153_04985	COG2824	Alkylphosphonate utilization operon protein PhnA
FY153_04990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY153_04995	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY153_05000	COG0154	amidase activity
FY153_05005	COG0456	acetyltransferase
FY153_05010	COG3811	Belongs to the UPF0386 family
FY153_05025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY153_05035	COG0456	acetyltransferase
FY153_05055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY153_05060	COG0439	Biotin carboxylase
FY153_05065	COG0511	ligase activity, forming carbon-carbon bonds
FY153_05070	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY153_05080	COG0436	Aminotransferase
FY153_05100	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_05105	COG1530	ribonuclease E activity
FY153_05115	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY153_05135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY153_05140	COG0384	phenazine biosynthesis protein PhzF
FY153_05160	COG0633	Ferredoxin
FY153_05175	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY153_05180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY153_05190	COG3768	UPF0283 membrane protein
FY153_05195	COG3106	COG3106 Predicted ATPase
FY153_05225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY153_05260	COG0537	adenosine 5'-monophosphoramidase activity
FY153_05285	COG0052	Belongs to the universal ribosomal protein uS2 family
FY153_05290	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY153_05295	COG0528	UMP kinase activity
FY153_05300	COG0233	cytoplasmic translational termination
FY153_05305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY153_05315	COG0750	zinc metalloprotease
FY153_05320	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY153_05325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY153_05330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY153_05335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY153_05340	COG3494	Protein of unknown function (DUF1009)
FY153_05345	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY153_05350	COG2186	Transcriptional regulator
FY153_05360	COG0765	amino acid transport
FY153_05365	COG0765	amino acid transport
FY153_05375	COG0372	Belongs to the citrate synthase family
FY153_05390	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY153_05400	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY153_05405	COG0148	phosphopyruvate hydratase activity
FY153_05415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY153_05420	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY153_05420	COG0022	dehydrogenase e1 component
FY153_05425	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY153_05435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY153_05445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY153_05450	COG0697	spore germination
FY153_05465	COG2867	negative regulation of translational initiation
FY153_05470	COG1058	Belongs to the CinA family
FY153_05470	COG1546	Belongs to the CinA family
FY153_05475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY153_05475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY153_05485	COG3852	Histidine kinase
FY153_05490	COG2204	response regulator
FY153_05495	COG5000	phosphorelay sensor kinase activity
FY153_05500	COG2204	response regulator
FY153_05505	COG0569	domain protein
FY153_05510	COG1923	regulation of RNA biosynthetic process
FY153_05515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY153_05520	COG3956	TIGRFAM MazG family protein
FY153_05530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY153_05530	COG1648	precorrin-2 dehydrogenase activity
FY153_05570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY153_05570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY153_05575	COG0509	glycine decarboxylation via glycine cleavage system
FY153_05580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY153_05605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY153_05610	COG0564	pseudouridine synthase activity
FY153_05630	COG0251	oxidation-reduction process
FY153_05635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY153_05645	COG1671	Belongs to the UPF0178 family
FY153_05660	COG0450	alkyl hydroperoxide reductase
FY153_05665	COG0625	glutathione transferase activity
FY153_05675	COG2801	Transposase and inactivated derivatives
FY153_05680	COG0431	NADPH-dependent FMN reductase
FY153_05690	COG0798	PFAM Bile acid sodium symporter
FY153_05695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY153_05710	COG0321	lipoyl(octanoyl) transferase activity
FY153_05710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY153_05715	COG0084	hydrolase, TatD family'
FY153_05720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY153_05730	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY153_05785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY153_05790	COG2095	MarC family integral membrane protein
FY153_05795	COG0617	tRNA 3'-terminal CCA addition
FY153_05795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY153_05795	COG0517	IMP dehydrogenase activity
FY153_05805	COG0629	single-stranded DNA binding
FY153_05810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY153_05820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY153_05825	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY153_05840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY153_05845	COG1121	(ABC) transporter
FY153_05865	COG0667	Aldo Keto reductase
FY153_05875	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY153_05960	COG2239	Acts as a magnesium transporter
FY153_05965	COG0243	molybdopterin cofactor binding
FY153_05975	COG0242	peptide deformylase activity
FY153_05985	COG2205	protein histidine kinase activity
FY153_05985	COG2202	Pas domain
FY153_05995	COG0321	lipoyl(octanoyl) transferase activity
FY153_06000	COG1064	alcohol dehydrogenase
FY153_06030	COG1862	Preprotein translocase
FY153_06050	COG2124	cytochrome p450
FY153_06065	COG0596	Alpha beta hydrolase
FY153_06080	COG0626	cystathionine gamma-synthase activity
FY153_06085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_06090	COG4597	amino acid ABC transporter
FY153_06095	COG0765	amino acid transport
FY153_06100	COG1126	abc transporter atp-binding protein
FY153_06115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY153_06130	COG0436	Aminotransferase
FY153_06160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY153_06170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY153_06175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY153_06180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY153_06195	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY153_06200	COG1489	DNA binding
FY153_06205	COG0024	Methionine aminopeptidase
FY153_06210	COG2003	Belongs to the UPF0758 family
FY153_06225	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY153_06250	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY153_06255	COG0546	phosphoglycolate phosphatase activity
FY153_06265	COG0114	fumarate hydratase activity
FY153_06275	COG0504	CTP synthase activity
FY153_06285	COG0149	triose-phosphate isomerase activity
FY153_06295	COG0187	DNA topoisomerase II activity
FY153_06305	COG0740	serine-type endopeptidase activity
FY153_06315	COG0640	Transcriptional regulator
FY153_06320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY153_06325	COG0745	RESPONSE REGULATOR receiver
FY153_06340	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY153_06340	COG3264	Mechanosensitive ion channel
FY153_06400	COG1127	ABC transporter
FY153_06405	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY153_06410	COG4948	Mandelate Racemase Muconate Lactonizing
FY153_06420	COG0280	phosphate acetyltransferase
FY153_06420	COG0281	malic enzyme
FY153_06430	COG0778	Nitroreductase
FY153_06435	COG0823	Involved in the tonB-independent uptake of proteins
FY153_06450	COG1368	sulfuric ester hydrolase activity
FY153_06470	COG3265	gluconokinase activity
FY153_06475	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY153_06495	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY153_06515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY153_06530	COG0318	PFAM AMP-dependent synthetase and ligase
FY153_06540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY153_06540	COG0512	Glutamine amidotransferase of anthranilate synthase
FY153_06545	COG0343	queuine tRNA-ribosyltransferase activity
FY153_06550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY153_06565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY153_06580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY153_06585	COG0134	indole-3-glycerol-phosphate synthase activity
FY153_06590	COG0315	cyclic pyranopterin monophosphate synthase activity
FY153_06595	COG0303	'Molybdopterin
FY153_06600	COG3706	GGDEF domain
FY153_06610	COG0475	glutathione-regulated potassium exporter activity
FY153_06610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY153_06620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY153_06630	COG2814	Major facilitator Superfamily
FY153_06635	COG0746	molybdenum cofactor guanylyltransferase activity
FY153_06640	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY153_06645	COG0739	heme binding
FY153_06650	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY153_06655	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY153_06660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY153_06665	COG0805	protein transport
FY153_06670	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY153_06675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY153_06680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY153_06685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY153_06690	COG1472	Belongs to the glycosyl hydrolase 3 family
FY153_06700	COG0018	arginyl-trna synthetase
FY153_06705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY153_06730	COG0525	valine-tRNA ligase activity
FY153_06740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY153_06985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY153_06995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FY153_07200	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY153_07205	COG1058	Belongs to the CinA family
FY153_07205	COG1546	Belongs to the CinA family
FY153_07210	COG0589	response to stress
FY153_07215	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY153_07225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY153_07285	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY153_07305	COG0515	serine threonine protein kinase
FY153_07305	COG2815	serine threonine protein kinase
FY153_07325	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_07330	COG0583	DNA-binding transcription factor activity
FY153_07335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY153_07400	COG0640	Transcriptional regulator
FY153_07405	COG1914	H( )-stimulated, divalent metal cation uptake system
FY153_07415	COG1132	(ABC) transporter
FY153_07420	COG0628	permease
FY153_07455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY153_07465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY153_07475	COG0302	gtp cyclohydrolase
FY153_07480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY153_07485	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY153_07495	COG0517	IMP dehydrogenase activity
FY153_07495	COG0516	GMP reductase activity
FY153_07530	COG1760	l-serine dehydratase
FY153_07570	COG0583	DNA-binding transcription factor activity
FY153_07585	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY153_07585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY153_07595	COG0347	Belongs to the P(II) protein family
FY153_07600	COG0174	glutamine synthetase
FY153_07630	COG0697	spore germination
FY153_07640	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY153_07650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY153_07680	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY153_07685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY153_07690	COG2186	Transcriptional regulator
FY153_07700	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY153_07705	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY153_07710	COG3845	ABC transporter
FY153_07715	COG1183	phosphatidylcholine synthase activity
FY153_07720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY153_07725	COG0679	Auxin Efflux Carrier
FY153_07730	COG0785	Cytochrome C biogenesis protein
FY153_07750	COG1278	Cold shock
FY153_07800	COG1136	(ABC) transporter
FY153_07800	COG0577	efflux transmembrane transporter activity
FY153_07805	COG0577	efflux transmembrane transporter activity
FY153_07805	COG1136	(ABC) transporter
FY153_07830	COG2151	metal-sulfur cluster biosynthetic enzyme
FY153_07835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY153_07840	COG0719	Fe-S assembly protein
FY153_07845	COG0396	ATPase activity
FY153_07850	COG0719	Fe-S assembly protein
FY153_07855	COG1104	cysteine desulfurase activity
FY153_07860	COG2945	thiolester hydrolase activity
FY153_07865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY153_07870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY153_07880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY153_07885	COG2833	Protein of unknown function (DUF455)
FY153_07890	COG0739	heme binding
FY153_07895	COG0513	Belongs to the DEAD box helicase family
FY153_07920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY153_07930	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY153_07935	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY153_07940	COG0047	phosphoribosylformylglycinamidine synthase activity
FY153_07955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY153_07960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY153_07980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY153_07985	COG2814	Major facilitator Superfamily
FY153_07990	COG0483	inositol monophosphate 1-phosphatase activity
FY153_07995	COG0483	inositol monophosphate 1-phosphatase activity
FY153_08000	COG0037	tRNA processing
FY153_08005	COG2066	Belongs to the glutaminase family
FY153_08010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY153_08015	COG0861	Integral membrane protein TerC family
FY153_08030	COG1280	lysine exporter protein (LysE YggA)
FY153_08040	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY153_08045	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY153_08055	COG0538	isocitrate dehydrogenase activity
FY153_08065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY153_08070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY153_08075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_08080	COG2313	pseudouridylate synthase activity
FY153_08090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_08095	COG4215	(ABC) transporter
FY153_08105	COG5425	PFAM Usg family protein
FY153_08115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY153_08120	COG1522	sequence-specific DNA binding
FY153_08125	COG1573	uracil-dna glycosylase
FY153_08135	COG2205	protein histidine kinase activity
FY153_08135	COG2202	Pas domain
FY153_08145	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY153_08150	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY153_08165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY153_08170	COG0842	Transport permease protein
FY153_08175	COG1131	(ABC) transporter
FY153_08180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY153_08180	COG0730	response to heat
FY153_08200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY153_08205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY153_08225	COG0129	dihydroxy-acid dehydratase activity
FY153_08230	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY153_08235	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY153_08245	COG3739	integral membrane protein
FY153_08255	COG0203	ribosomal protein L17
FY153_08260	COG0202	RNA polymerase activity
FY153_08265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY153_08270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY153_08275	COG0563	adenylate kinase activity
FY153_08280	COG0201	protein transport
FY153_08285	COG0200	Binds to the 23S rRNA
FY153_08290	COG1841	ribosomal large subunit assembly
FY153_08295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY153_08300	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY153_08305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY153_08310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY153_08315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY153_08320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY153_08325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY153_08330	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY153_08335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY153_08340	COG0255	Belongs to the universal ribosomal protein uL29 family
FY153_08345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY153_08350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY153_08355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY153_08360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY153_08365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY153_08370	COG0089	rRNA binding
FY153_08375	COG0088	Forms part of the polypeptide exit tunnel
FY153_08380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY153_08385	COG0051	transcription antitermination factor activity, RNA binding
FY153_08390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY153_08395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY153_08400	COG0049	tRNA binding
FY153_08405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY153_08425	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY153_08430	COG0085	RNA polymerase activity
FY153_08435	COG0222	ribosome binding
FY153_08440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY153_08445	COG0081	regulation of translation
FY153_08450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY153_08460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY153_08470	COG1086	Polysaccharide biosynthesis protein
FY153_08475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY153_08480	COG0861	Integral membrane protein TerC family
FY153_08485	COG3895	Periplasmic Protein
FY153_08505	COG1132	(ABC) transporter
FY153_08510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY153_08530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY153_08565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_08565	COG0784	Response regulator, receiver
FY153_08565	COG2205	protein histidine kinase activity
FY153_08565	COG2198	Histidine kinase
FY153_08570	COG0784	Response regulator, receiver
FY153_08575	COG2202	Pas domain
FY153_08575	COG3920	Histidine kinase
FY153_08580	COG0784	Response regulator, receiver
FY153_08585	COG4251	negative regulation of phosphorylation
FY153_08600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY153_08605	COG1607	acyl-coa hydrolase
FY153_08625	COG2910	NAD(P)H-binding
FY153_08630	COG1733	regulation of RNA biosynthetic process
FY153_08645	COG0556	nucleotide-excision repair
FY153_08655	COG2382	esterase
FY153_08675	COG0484	heat shock protein binding
FY153_08695	COG3706	GGDEF domain
FY153_08715	COG1840	ABC-type Fe3 transport system, periplasmic component
FY153_08720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY153_08735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY153_08745	COG2207	Transcriptional regulator
FY153_08750	COG1064	alcohol dehydrogenase
FY153_08755	COG1252	NADH dehydrogenase
FY153_08760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY153_08770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY153_08805	COG0656	L-ascorbic acid biosynthetic process
FY153_08820	COG0440	acetolactate synthase activity
FY153_08825	COG0028	Belongs to the TPP enzyme family
FY153_08840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY153_08845	COG0560	Phosphoserine phosphatase
FY153_08845	COG3830	Belongs to the UPF0237 family
FY153_08865	COG0330	HflC and HflK could
FY153_08870	COG0330	HflC and HflK could
FY153_08880	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY153_08915	COG0277	FAD linked oxidase domain protein
FY153_08920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY153_08960	COG1335	isochorismatase
FY153_08985	COG2264	protein methyltransferase activity
FY153_08990	COG1999	signal sequence binding
FY153_09000	COG0835	chemotaxis
FY153_09010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY153_09015	COG0583	DNA-binding transcription factor activity
FY153_09025	COG1247	-acetyltransferase
FY153_09035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY153_09040	COG0497	DNA recombination
FY153_09045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY153_09055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY153_09060	COG0849	cell division
FY153_09065	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY153_09070	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY153_09075	COG0477	Major facilitator Superfamily
FY153_09080	COG5001	Diguanylate cyclase
FY153_09085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY153_09090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY153_09095	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY153_09105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY153_09110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY153_09120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY153_09135	COG0275	rRNA processing
FY153_09140	COG2001	Belongs to the MraZ family
FY153_09165	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY153_09195	COG4106	trans-aconitate 2-methyltransferase activity
FY153_09215	COG2226	methyltransferase
FY153_09225	COG2267	carboxylic ester hydrolase activity
FY153_09230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY153_09245	COG0251	oxidation-reduction process
FY153_09260	COG1376	ErfK ybiS ycfS ynhG family protein
FY153_09265	COG2814	Major facilitator Superfamily
FY153_09295	COG1012	belongs to the aldehyde dehydrogenase family
FY153_09300	COG0174	glutamine synthetase
FY153_09305	COG0531	amino acid
FY153_09315	COG1737	Transcriptional regulator
FY153_09320	COG2182	Extracellular solute-binding protein
FY153_09335	COG3842	ATPase activity
FY153_09400	COG2968	Membrane
FY153_09410	COG0432	Pfam Uncharacterised protein family UPF0047
FY153_09425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY153_09430	COG0358	DNA primase activity
FY153_09450	COG0505	Belongs to the CarA family
FY153_09455	COG0534	Mate efflux family protein
FY153_09470	COG2321	neutral zinc metallopeptidase
FY153_09485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY153_09495	COG3706	GGDEF domain
FY153_09510	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY153_09520	COG1522	sequence-specific DNA binding
FY153_09525	COG0492	ferredoxin-NADP+ reductase activity
FY153_09530	COG0583	DNA-binding transcription factor activity
FY153_09540	COG1902	pentaerythritol trinitrate reductase activity
FY153_09565	COG0387	Pfam Sodium calcium exchanger
FY153_09570	COG0436	Aminotransferase
FY153_09575	COG2199	diguanylate cyclase activity
FY153_09575	COG2200	EAL domain
FY153_09590	COG1278	Cold shock
FY153_09595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY153_09605	COG1846	Transcriptional regulator
FY153_09610	COG0745	RESPONSE REGULATOR receiver
FY153_09620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY153_09640	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY153_09650	COG1496	oxidoreductase activity
FY153_09665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY153_09675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY153_09690	COG0840	transmembrane signaling receptor activity
FY153_09695	COG1012	belongs to the aldehyde dehydrogenase family
FY153_09700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY153_09705	COG3300	MHYT domain
FY153_09705	COG5001	Diguanylate cyclase
FY153_09710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY153_09715	COG5001	Diguanylate cyclase
FY153_09725	COG0193	aminoacyl-tRNA hydrolase activity
FY153_09735	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY153_09760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY153_09770	COG2857	Cytochrome c1
FY153_09770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY153_09790	COG1132	(ABC) transporter
FY153_09795	COG1132	(ABC) transporter
FY153_09805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY153_09820	COG0408	coproporphyrinogen oxidase activity
FY153_09835	COG0617	tRNA 3'-terminal CCA addition
FY153_09850	COG0714	Associated with various cellular activities
FY153_09870	COG0454	-acetyltransferase
FY153_09885	COG0477	Major facilitator Superfamily
FY153_09895	COG0435	Glutathione S-transferase
FY153_09900	COG0494	nUDIX hydrolase
FY153_09910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY153_09915	COG3135	benzoate transporter
FY153_09940	COG0740	serine-type endopeptidase activity
FY153_09955	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY153_09960	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY153_09985	COG4175	Glycine betaine
FY153_10005	COG1435	thymidine kinase activity
FY153_10030	COG1629	transport
FY153_10030	COG4771	TonB-dependent receptor
FY153_10040	COG0512	Glutamine amidotransferase of anthranilate synthase
FY153_10040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY153_10055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY153_10065	COG0366	Alpha amylase catalytic
FY153_10070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_10090	COG1160	GTP binding
FY153_10110	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY153_10120	COG0024	Methionine aminopeptidase
FY153_10130	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_10150	COG0583	DNA-binding transcription factor activity
FY153_10165	COG0402	S-adenosylhomocysteine deaminase activity
FY153_10185	COG1309	transcriptional regulator
FY153_10190	COG1686	Belongs to the peptidase S11 family
FY153_10200	COG2351	hydroxyisourate hydrolase activity
FY153_10205	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY153_10220	COG3648	Uricase
FY153_10220	COG3195	allantoin biosynthetic process
FY153_10230	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY153_10240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_10240	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY153_10250	COG0513	Belongs to the DEAD box helicase family
FY153_10260	COG2259	Doxx family
FY153_10265	COG1376	ErfK ybiS ycfS ynhG family protein
FY153_10275	COG2308	Evidence 4 Homologs of previously reported genes of
FY153_10285	COG1305	Transglutaminase-like
FY153_10310	COG4214	carbohydrate transport
FY153_10320	COG4213	ABC transporter substrate-binding protein
FY153_10355	COG0840	transmembrane signaling receptor activity
FY153_10355	COG2972	Histidine kinase
FY153_10370	COG1410	methionine synthase
FY153_10370	COG0646	methionine synthase
FY153_10415	COG1215	transferase activity, transferring glycosyl groups
FY153_10445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY153_10460	COG2346	COG2346, Truncated hemoglobins
FY153_10480	COG1309	transcriptional regulator
FY153_10495	COG0494	nUDIX hydrolase
FY153_10505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_10510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_10540	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY153_10545	COG0830	nickel cation binding
FY153_10550	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY153_10565	COG0804	urea catabolic process
FY153_10570	COG1442	glycosyl transferase family 8
FY153_10575	COG3755	Protein conserved in bacteria
FY153_10585	COG0832	Belongs to the urease beta subunit family
FY153_10590	COG3813	Protein conserved in bacteria
FY153_10595	COG0831	urea catabolic process
FY153_10600	COG0829	nickel cation binding
FY153_10625	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY153_10640	COG0174	glutamine synthetase
FY153_10645	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_10650	COG2198	Histidine kinase
FY153_10650	COG0784	Response regulator, receiver
FY153_10650	COG5002	protein histidine kinase activity
FY153_10665	COG0726	polysaccharide deacetylase
FY153_10700	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY153_10775	COG0564	pseudouridine synthase activity
FY153_10785	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY153_10795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY153_10820	COG0346	lactoylglutathione lyase activity
FY153_10830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY153_10840	COG2832	Protein of unknown function (DUF454)
FY153_10845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY153_10850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_10855	COG4558	Periplasmic binding protein
FY153_10865	COG3721	Heme iron utilization protein
FY153_10880	COG3655	Transcriptional regulator
FY153_10905	COG2205	protein histidine kinase activity
FY153_10950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_10955	COG4605	iron ion homeostasis
FY153_10960	COG4604	ABC transporter, ATP-binding protein
FY153_10965	COG0783	Belongs to the Dps family
FY153_10980	COG2972	Histidine kinase
FY153_10980	COG0840	transmembrane signaling receptor activity
FY153_10985	COG0656	L-ascorbic acid biosynthetic process
FY153_10990	COG2814	Major facilitator Superfamily
FY153_11000	COG0583	DNA-binding transcription factor activity
FY153_11005	COG0657	acetylesterase activity
FY153_11010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_11030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY153_11035	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY153_11040	COG0288	reversible hydration of carbon dioxide
FY153_11050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY153_11070	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY153_11075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY153_11080	COG0778	Nitroreductase
FY153_11085	COG2267	carboxylic ester hydrolase activity
FY153_11090	COG0251	oxidation-reduction process
FY153_11095	COG1335	isochorismatase
FY153_11100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_11110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_11125	COG1175	transmembrane transport
FY153_11130	COG0395	ABC-type sugar transport system, permease component
FY153_11135	COG3842	ATPase activity
FY153_11140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_11150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY153_11165	COG4608	Belongs to the ABC transporter superfamily
FY153_11170	COG0444	Belongs to the ABC transporter superfamily
FY153_11175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_11180	COG0601	transmembrane transport
FY153_11235	COG2159	amidohydrolase
FY153_11240	COG1960	acyl-CoA dehydrogenase activity
FY153_11270	COG0745	RESPONSE REGULATOR receiver
FY153_11280	COG1902	pentaerythritol trinitrate reductase activity
FY153_11280	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY153_11285	COG3842	ATPase activity
FY153_11295	COG1840	ABC-type Fe3 transport system, periplasmic component
FY153_11300	COG1840	ABC-type Fe3 transport system, periplasmic component
FY153_11305	COG0745	RESPONSE REGULATOR receiver
FY153_11315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY153_11320	COG0583	DNA-binding transcription factor activity
FY153_11325	COG1278	Cold shock
FY153_11360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY153_11365	COG1309	transcriptional regulator
FY153_11370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_11375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY153_11385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY153_11390	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY153_11410	COG0583	DNA-binding transcription factor activity
FY153_11415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_11420	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY153_11425	COG4149	molybdate abc transporter
FY153_11430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY153_11445	COG2022	thiamine diphosphate biosynthetic process
FY153_11460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY153_11470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY153_11480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY153_11500	COG1132	(ABC) transporter
FY153_11505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY153_11550	COG4166	transmembrane transport
FY153_11555	COG0601	transmembrane transport
FY153_11560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_11575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY153_11580	COG3142	Participates in the control of copper homeostasis
FY153_11585	COG2814	Major facilitator Superfamily
FY153_11600	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_11605	COG1737	Transcriptional regulator
FY153_11615	COG3842	ATPase activity
FY153_11625	COG0395	ABC-type sugar transport system, permease component
FY153_11640	COG2188	Transcriptional regulator
FY153_11645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY153_11650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY153_11655	COG1940	carbohydrate kinase activity
FY153_11665	COG0671	phosphoesterase, PA-phosphatase related
FY153_11670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY153_11675	COG0156	8-amino-7-oxononanoate synthase activity
FY153_11685	COG0729	surface antigen
FY153_11695	COG0835	chemotaxis
FY153_11705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY153_11710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY153_11715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY153_11720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY153_11725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY153_11730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY153_11745	COG4974	Belongs to the 'phage' integrase family
FY153_11770	COG1280	lysine exporter protein (LysE YggA)
FY153_11780	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY153_11785	COG0567	Dehydrogenase, E1 component
FY153_11790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY153_11795	COG0045	succinate-CoA ligase (ADP-forming) activity
FY153_11800	COG0039	L-malate dehydrogenase activity
FY153_11805	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY153_11840	COG2264	protein methyltransferase activity
FY153_11855	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY153_11860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY153_11865	COG0181	hydroxymethylbilane synthase activity
FY153_11905	COG1872	DUF167
FY153_11910	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY153_11920	COG1217	gtp-binding protein TYPA
FY153_11925	COG0339	signal peptide processing
FY153_11930	COG1846	Transcriptional regulator
FY153_11940	COG0137	argininosuccinate synthase activity
FY153_11950	COG1280	lysine exporter protein (LysE YggA)
FY153_11955	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY153_11960	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY153_11970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY153_11985	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY153_11990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY153_11995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY153_12005	COG4181	ATPase activity
FY153_12015	COG0670	Belongs to the BI1 family
FY153_12030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY153_12035	COG4133	protoheme IX ABC transporter activity
FY153_12040	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY153_12045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY153_12070	COG2917	probably involved in intracellular septation
FY153_12075	COG0552	protein localization to endoplasmic reticulum
FY153_12080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY153_12085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY153_12095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY153_12100	COG0287	Prephenate dehydrogenase
FY153_12100	COG1605	Chorismate mutase
FY153_12105	COG0228	four-way junction DNA binding
FY153_12110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY153_12115	COG0336	Belongs to the RNA methyltransferase TrmD family
FY153_12125	COG0335	large ribosomal subunit rRNA binding
FY153_12130	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY153_12135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_12150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY153_12170	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY153_12190	COG0488	(ABC) transporter
FY153_12200	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY153_12210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY153_12215	COG0142	geranyltranstransferase activity
FY153_12220	COG2885	chlorophyll binding
FY153_12225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY153_12230	COG2223	nitrite transmembrane transporter activity
FY153_12235	COG1349	DNA-binding transcription factor activity
FY153_12240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY153_12245	COG2197	response regulator
FY153_12250	COG1132	(ABC) transporter
FY153_12260	COG3459	Glycosyltransferase 36 associated
FY153_12265	COG1473	amidohydrolase
FY153_12270	COG0579	oxidoreductase
FY153_12280	COG0129	dihydroxy-acid dehydratase activity
FY153_12285	COG2084	Dehydrogenase
FY153_12290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY153_12295	COG0277	FAD linked oxidase domain protein
FY153_12300	COG2186	Transcriptional regulator
FY153_12310	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY153_12315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY153_12320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY153_12325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY153_12335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY153_12340	COG0495	leucyl-tRNA aminoacylation
FY153_12355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY153_12360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY153_12375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY153_12380	COG1946	Acyl-CoA thioesterase
FY153_12385	COG0347	Belongs to the P(II) protein family
FY153_12390	COG0004	ammonium transporteR
FY153_12395	COG1674	ftsk spoiiie
FY153_12400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY153_12415	COG0745	RESPONSE REGULATOR receiver
FY153_12425	COG1329	Transcriptional regulator
FY153_12435	COG2270	Major facilitator Superfamily
FY153_12450	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_12465	COG0494	nUDIX hydrolase
FY153_12470	COG2861	carbohydrate metabolic process
FY153_12475	COG0793	Belongs to the peptidase S41A family
FY153_12485	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY153_12490	COG0799	negative regulation of ribosome biogenesis
FY153_12495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY153_12500	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY153_12505	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY153_12510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY153_12525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY153_12530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY153_12555	COG0066	3-isopropylmalate dehydratase activity
FY153_12560	COG0473	3-isopropylmalate dehydrogenase activity
FY153_12565	COG1858	cytochrome C peroxidase
FY153_12570	COG1797	cobyrinic acid a,c-diamide synthase activity
FY153_12580	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY153_12645	COG1492	cobalamin metabolic process
FY153_12660	COG4948	Mandelate Racemase Muconate Lactonizing
FY153_12665	COG3254	rhamnose metabolic process
FY153_12675	COG1063	alcohol dehydrogenase
FY153_12700	COG1129	ABC transporter
FY153_12705	COG2186	Transcriptional regulator
FY153_12710	COG2721	sulfolactate sulfo-lyase activity
FY153_12715	COG0138	bifunctional purine biosynthesis protein purh
FY153_12725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY153_12725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY153_12730	COG0501	Belongs to the peptidase M48B family
FY153_12750	COG0357	Ribosomal RNA small subunit methyltransferase G
FY153_12755	COG0445	tRNA wobble uridine modification
FY153_12760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY153_12765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY153_12770	COG1981	membrane
FY153_12775	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY153_12780	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY153_12785	COG0424	maF-like protein
FY153_12790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY153_12795	COG0237	dephospho-CoA kinase activity
FY153_12805	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY153_12810	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY153_12820	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY153_12845	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY153_12860	COG0135	phosphoribosylanthranilate isomerase activity
FY153_12865	COG0133	tryptophan synthase activity
FY153_12870	COG0159	tryptophan synthase activity
FY153_12875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY153_12890	COG1074	ATP-dependent DNA helicase activity
FY153_12900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY153_12905	COG0802	atpase or kinase
FY153_12910	COG2205	protein histidine kinase activity
FY153_12915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY153_12920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY153_12925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY153_12925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY153_12930	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY153_12935	COG0642	Histidine kinase
FY153_12940	COG0745	RESPONSE REGULATOR receiver
FY153_12945	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY153_12955	COG1652	LysM domain
FY153_12960	COG1072	(Pantothenic acid kinase))
FY153_12965	COG0140	phosphoribosyl-ATP diphosphatase activity
FY153_12970	COG0107	imidazoleglycerol-phosphate synthase activity
FY153_12975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY153_12980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY153_12990	COG0131	Imidazoleglycerol-phosphate dehydratase
FY153_12995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY153_13000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY153_13010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY153_13025	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY153_13035	COG1643	Atp-dependent helicase
FY153_13080	COG1940	carbohydrate kinase activity
FY153_13100	COG1072	(Pantothenic acid kinase))
FY153_13110	COG1780	Probably involved in ribonucleotide reductase function
FY153_13130	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY153_13160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_13170	COG2813	Specifically methylates the guanine in position
FY153_13175	COG1185	polyribonucleotide nucleotidyltransferase activity
FY153_13180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY153_13185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY153_13190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY153_13195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY153_13195	COG3064	Membrane
FY153_13210	COG0779	Required for maturation of 30S ribosomal subunits
FY153_13215	COG2814	Major facilitator Superfamily
FY153_13225	COG2951	lytic endotransglycosylase activity
FY153_13230	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY153_13240	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY153_13245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY153_13260	COG2816	NAD+ diphosphatase activity
FY153_13265	COG0077	Prephenate dehydratase
FY153_13265	COG1605	Chorismate mutase
FY153_13270	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY153_13275	COG3474	cytochrome
FY153_13285	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY153_13290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY153_13295	COG1278	Cold shock
FY153_13300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY153_13310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY153_13310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY153_13315	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY153_13345	COG2900	Belongs to the SlyX family
FY153_13355	COG0484	heat shock protein binding
FY153_13360	COG0443	Heat shock 70 kDa protein
FY153_13375	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY153_13380	COG1744	ABC transporter substrate-binding protein PnrA-like
FY153_13385	COG3845	ABC transporter
FY153_13390	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY153_13395	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY153_13400	COG0295	cytidine deaminase activity
FY153_13410	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY153_13415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY153_13425	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY153_13430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY153_13435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY153_13445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY153_13450	COG1845	cytochrome c oxidase, subunit III
FY153_13455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY153_13460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY153_13465	COG0477	Major facilitator Superfamily
FY153_13470	COG0067	glutamate synthase
FY153_13470	COG0069	glutamate synthase activity
FY153_13470	COG0070	glutamate synthase
FY153_13475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY153_13490	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY153_13500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY153_13530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_13550	COG0848	biopolymer transport protein
FY153_13560	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY153_13575	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY153_13580	COG3454	Phosphonate metabolism
FY153_13585	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY153_13590	COG3639	organic phosphonate transmembrane transporter activity
FY153_13595	COG3639	organic phosphonate transmembrane transporter activity
FY153_13605	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY153_13615	COG4778	phosphonate C-P lyase system protein PhnL
FY153_13620	COG4107	phosphonate C-P lyase system protein PhnK
FY153_13625	COG3627	carbon phosphorus lyase activity
FY153_13630	COG3626	phosphonate metabolism
FY153_13635	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY153_13640	COG3624	Phosphonate C-P lyase system protein PhnG
FY153_13645	COG2188	Transcriptional regulator
FY153_13650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY153_13655	COG0837	glucose binding
FY153_13660	COG1803	Methylglyoxal synthase
FY153_13665	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY153_13670	COG4166	transmembrane transport
FY153_13675	COG4174	ABC transporter (Permease)
FY153_13680	COG4239	(ABC) transporter, permease
FY153_13685	COG4172	Belongs to the ABC transporter superfamily
FY153_13690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_13695	COG0174	glutamine synthetase
FY153_13700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_13705	COG3265	gluconokinase activity
FY153_13710	COG1174	glycine betaine transport
FY153_13715	COG1125	glycine betaine transport
FY153_13720	COG1174	glycine betaine transport
FY153_13725	COG1732	Glycine betaine
FY153_13735	COG1959	2 iron, 2 sulfur cluster binding
FY153_13740	COG1840	ABC-type Fe3 transport system, periplasmic component
FY153_13750	COG4269	membrane
FY153_13765	COG0697	spore germination
FY153_13780	COG0791	NLP P60 protein
FY153_13790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY153_13795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY153_13830	COG4964	Belongs to the GSP D family
FY153_13875	COG3422	double-strand break repair
FY153_13880	COG3757	hydrolase, family 25
FY153_13885	COG0697	spore germination
FY153_13890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY153_13905	COG0492	ferredoxin-NADP+ reductase activity
FY153_13920	COG0481	GTPase activity
FY153_13925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY153_13940	COG1396	sequence-specific DNA binding
FY153_13955	COG1917	Cupin 2, conserved barrel domain protein
FY153_13955	COG2169	Transcriptional regulator
FY153_13960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY153_13985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY153_13990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY153_13995	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY153_14005	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY153_14010	COG0072	phenylalanine-tRNA ligase activity
FY153_14010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY153_14015	COG0667	Aldo Keto reductase
FY153_14035	COG4977	sequence-specific DNA binding
FY153_14060	COG1570	exodeoxyribonuclease VII activity
FY153_14065	COG4948	Mandelate Racemase Muconate Lactonizing
FY153_14075	COG1846	Transcriptional regulator
FY153_14080	COG0697	spore germination
FY153_14085	COG2309	aminopeptidase activity
FY153_14095	COG1393	Belongs to the ArsC family
FY153_14110	COG1309	transcriptional regulator
FY153_14120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY153_14120	COG0519	Catalyzes the synthesis of GMP from XMP
FY153_14135	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY153_14165	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY153_14175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY153_14185	COG1968	undecaprenyl-diphosphatase activity
FY153_14200	COG0284	orotidine-5'-phosphate decarboxylase activity
FY153_14210	COG3963	phosphatidate phosphatase activity
FY153_14220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY153_14225	COG0792	nuclease activity
FY153_14240	COG1175	transmembrane transport
FY153_14245	COG0395	ABC-type sugar transport system, permease component
FY153_14250	COG3842	ATPase activity
FY153_14260	COG0189	ligase activity
FY153_14265	COG0606	chelatase, subunit chli
FY153_14270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY153_14275	COG1280	lysine exporter protein (LysE YggA)
FY153_14280	COG0756	dUTP diphosphatase activity
FY153_14285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY153_14290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY153_14305	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY153_14310	COG2226	methyltransferase
FY153_14315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY153_14320	COG1024	Enoyl-CoA hydratase
FY153_14325	COG0268	Binds directly to 16S ribosomal RNA
FY153_14360	COG0411	ABC transporter
FY153_14365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY153_14370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY153_14375	COG1454	alcohol dehydrogenase
FY153_14380	COG0747	negative chemotaxis
FY153_14385	COG0601	transmembrane transport
FY153_14395	COG4608	Belongs to the ABC transporter superfamily
FY153_14400	COG1349	DNA-binding transcription factor activity
FY153_14405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY153_14430	COG4302	ethanolamine ammonia-lyase activity
FY153_14435	COG0025	NhaP-type Na H and K H
FY153_14440	COG4106	trans-aconitate 2-methyltransferase activity
FY153_14450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_14455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_14460	COG0601	transmembrane transport
FY153_14465	COG0747	negative chemotaxis
FY153_14485	COG4172	Belongs to the ABC transporter superfamily
FY153_14510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY153_14510	COG0785	Cytochrome C biogenesis protein
FY153_14520	COG0596	Alpha beta hydrolase
FY153_14535	COG1764	response to oxidative stress
FY153_14545	COG0596	Alpha beta hydrolase
FY153_14560	COG0783	Belongs to the Dps family
FY153_14565	COG0243	molybdopterin cofactor binding
FY153_14575	COG4566	intracellular signal transduction
FY153_14580	COG4566	intracellular signal transduction
FY153_14590	COG2140	Oxalate decarboxylase
FY153_14605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY153_14605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY153_14610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY153_14620	COG1414	Transcriptional regulator
FY153_14635	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_14655	COG1522	sequence-specific DNA binding
FY153_14680	COG0628	permease
FY153_14690	COG2235	arginine
FY153_14725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY153_14735	COG0702	epimerase
FY153_14740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY153_14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_14750	COG0745	RESPONSE REGULATOR receiver
FY153_14755	COG5002	protein histidine kinase activity
FY153_14770	COG2233	PERMEase
FY153_14830	COG0395	ABC-type sugar transport system, permease component
FY153_14835	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_14845	COG3842	ATPase activity
FY153_14880	COG1653	transport
FY153_14890	COG0395	ABC-type sugar transport system, permease component
FY153_14895	COG3842	ATPase activity
FY153_14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY153_14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_14920	COG1116	anion transmembrane transporter activity
FY153_14925	COG0395	ABC-type sugar transport system, permease component
FY153_14930	COG1175	transmembrane transport
FY153_14960	COG1609	Transcriptional regulator
FY153_14975	COG1082	Xylose isomerase domain protein TIM barrel
FY153_14980	COG3842	ATPase activity
FY153_14985	COG0395	ABC-type sugar transport system, permease component
FY153_14990	COG1175	transmembrane transport
FY153_14995	COG1653	transport
FY153_15000	COG1309	transcriptional regulator
FY153_15005	COG0673	inositol 2-dehydrogenase activity
FY153_15020	COG0673	inositol 2-dehydrogenase activity
FY153_15025	COG1278	Cold shock
FY153_15035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY153_15055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY153_15060	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY153_15075	COG3842	ATPase activity
FY153_15080	COG0395	ABC-type sugar transport system, permease component
FY153_15085	COG1175	transmembrane transport
FY153_15095	COG3618	amidohydrolase
FY153_15100	COG4948	Mandelate Racemase Muconate Lactonizing
FY153_15105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_15110	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_15115	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY153_15120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY153_15125	COG2186	Transcriptional regulator
FY153_15140	COG0667	Aldo Keto reductase
FY153_15170	COG4977	sequence-specific DNA binding
FY153_15175	COG2223	nitrite transmembrane transporter activity
FY153_15180	COG1609	Transcriptional regulator
FY153_15185	COG1063	alcohol dehydrogenase
FY153_15190	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_15200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_15205	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY153_15210	COG1175	transmembrane transport
FY153_15215	COG0395	ABC-type sugar transport system, permease component
FY153_15230	COG0395	ABC-type sugar transport system, permease component
FY153_15240	COG2182	Extracellular solute-binding protein
FY153_15245	COG0626	cystathionine gamma-synthase activity
FY153_15260	COG0454	-acetyltransferase
FY153_15265	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY153_15275	COG1121	(ABC) transporter
FY153_15280	COG0523	cobalamin synthesis protein
FY153_15295	COG0523	cobalamin synthesis protein
FY153_15300	COG1653	transport
FY153_15305	COG1175	transmembrane transport
FY153_15310	COG0395	ABC-type sugar transport system, permease component
FY153_15315	COG3842	ATPase activity
FY153_15325	COG3047	cAMP biosynthetic process
FY153_15350	COG0583	DNA-binding transcription factor activity
FY153_15355	COG1879	ABC-type sugar transport system periplasmic component
FY153_15360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_15365	COG1129	ABC transporter
FY153_15375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY153_15380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_15390	COG3257	ureidoglycine aminohydrolase activity
FY153_15400	COG5001	Diguanylate cyclase
FY153_15405	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY153_15415	COG0747	negative chemotaxis
FY153_15420	COG0601	transmembrane transport
FY153_15425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_15435	COG4608	Belongs to the ABC transporter superfamily
FY153_15440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY153_15455	COG0346	lactoylglutathione lyase activity
FY153_15465	COG0129	dihydroxy-acid dehydratase activity
FY153_15470	COG1879	ABC-type sugar transport system periplasmic component
FY153_15475	COG1129	ABC transporter
FY153_15480	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_15485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_15490	COG2186	Transcriptional regulator
FY153_15505	COG2226	methyltransferase
FY153_15510	COG0587	DNA-directed DNA polymerase activity
FY153_15540	COG0673	inositol 2-dehydrogenase activity
FY153_15550	COG3842	ATPase activity
FY153_15555	COG0395	ABC-type sugar transport system, permease component
FY153_15560	COG1175	transmembrane transport
FY153_15565	COG1653	transport
FY153_15575	COG0673	inositol 2-dehydrogenase activity
FY153_15590	COG5001	Diguanylate cyclase
FY153_15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_15605	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY153_15610	COG2894	cell division
FY153_15615	COG0850	regulation of cytokinetic process
FY153_15620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY153_15625	COG2186	Transcriptional regulator
FY153_15630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY153_15640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY153_15645	COG1063	alcohol dehydrogenase
FY153_15650	COG1312	Catalyzes the dehydration of D-mannonate
FY153_15670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY153_15675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY153_15675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY153_15680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_15695	COG0625	glutathione transferase activity
FY153_15700	COG4172	Belongs to the ABC transporter superfamily
FY153_15705	COG1921	L-seryl-tRNASec selenium transferase activity
FY153_15720	COG3964	amidohydrolase
FY153_15730	COG0601	transmembrane transport
FY153_15735	COG0747	negative chemotaxis
FY153_15740	COG0438	transferase activity, transferring glycosyl groups
FY153_15775	COG4989	oxidoreductase activity
FY153_15785	COG2188	Transcriptional regulator
FY153_15790	COG3842	ATPase activity
FY153_15795	COG1653	transport
FY153_15800	COG1175	transmembrane transport
FY153_15805	COG0395	ABC-type sugar transport system, permease component
FY153_15810	COG1501	Belongs to the glycosyl hydrolase 31 family
FY153_15820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_15825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY153_15830	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY153_15835	COG0352	thiamine-phosphate diphosphorylase activity
FY153_15840	COG0351	phosphomethylpyrimidine kinase
FY153_15845	COG1522	sequence-specific DNA binding
FY153_15850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY153_15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_15870	COG2204	response regulator
FY153_15875	COG4191	Histidine kinase
FY153_15880	COG1301	dicarboxylic acid transport
FY153_15885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY153_15890	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_15900	COG1473	amidohydrolase
FY153_15920	COG1215	transferase activity, transferring glycosyl groups
FY153_15930	COG2942	2-epimerase
FY153_15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY153_15965	COG2197	response regulator
FY153_15995	COG3307	-O-antigen
FY153_16000	COG1596	polysaccharide export
FY153_16005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY153_16015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY153_16020	COG0840	transmembrane signaling receptor activity
FY153_16020	COG2972	Histidine kinase
FY153_16025	COG1376	ErfK ybiS ycfS ynhG family protein
FY153_16035	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_16045	COG2094	Belongs to the DNA glycosylase MPG family
FY153_16060	COG1609	Transcriptional regulator
FY153_16065	COG1653	transport
FY153_16080	COG3842	ATPase activity
FY153_16090	COG0673	inositol 2-dehydrogenase activity
FY153_16095	COG0602	queuosine metabolic process
FY153_16100	COG0720	synthase
FY153_16105	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY153_16110	COG0673	inositol 2-dehydrogenase activity
FY153_16125	COG0395	ABC-type sugar transport system, permease component
FY153_16130	COG1175	transmembrane transport
FY153_16155	COG0583	DNA-binding transcription factor activity
FY153_16160	COG0280	phosphate acetyltransferase
FY153_16160	COG0281	malic enzyme
FY153_16175	COG0765	amino acid transport
FY153_16180	COG1126	abc transporter atp-binding protein
FY153_16185	COG2079	MmgE PrpD family protein
FY153_16190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_16215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY153_16225	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY153_16230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY153_16235	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_16240	COG1129	ABC transporter
FY153_16255	COG1473	amidohydrolase
FY153_16260	COG0747	negative chemotaxis
FY153_16275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_16280	COG0601	transmembrane transport
FY153_16285	COG0583	DNA-binding transcription factor activity
FY153_16290	COG1446	asparaginase
FY153_16305	COG0747	negative chemotaxis
FY153_16325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_16330	COG0601	transmembrane transport
FY153_16335	COG2197	response regulator
FY153_16340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY153_16345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY153_16360	COG0395	ABC-type sugar transport system, permease component
FY153_16365	COG1175	transmembrane transport
FY153_16375	COG0673	inositol 2-dehydrogenase activity
FY153_16380	COG0673	inositol 2-dehydrogenase activity
FY153_16400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_16405	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY153_16425	COG1595	DNA-templated transcription, initiation
FY153_16430	COG1120	ATPase activity
FY153_16435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_16450	COG2226	methyltransferase
FY153_16460	COG1120	ATPase activity
FY153_16465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_16510	COG1012	belongs to the aldehyde dehydrogenase family
FY153_16515	COG0473	3-isopropylmalate dehydrogenase activity
FY153_16520	COG1012	belongs to the aldehyde dehydrogenase family
FY153_16525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_16560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_16565	COG4172	Belongs to the ABC transporter superfamily
FY153_16570	COG1522	sequence-specific DNA binding
FY153_16580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_16595	COG0583	DNA-binding transcription factor activity
FY153_16605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_16610	COG1126	abc transporter atp-binding protein
FY153_16620	COG1473	amidohydrolase
FY153_16625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16635	COG1959	2 iron, 2 sulfur cluster binding
FY153_16645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY153_16650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16680	COG1960	acyl-CoA dehydrogenase activity
FY153_16690	COG0747	negative chemotaxis
FY153_16705	COG0444	Belongs to the ABC transporter superfamily
FY153_16715	COG0667	Aldo Keto reductase
FY153_16725	COG0583	DNA-binding transcription factor activity
FY153_16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16735	COG4166	transmembrane transport
FY153_16745	COG0747	negative chemotaxis
FY153_16750	COG1473	amidohydrolase
FY153_16755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_16785	COG1733	regulation of RNA biosynthetic process
FY153_16790	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_16810	COG4608	Belongs to the ABC transporter superfamily
FY153_16815	COG0444	Belongs to the ABC transporter superfamily
FY153_16825	COG0601	transmembrane transport
FY153_16835	COG2186	Transcriptional regulator
FY153_16850	COG0300	oxidoreductase activity
FY153_16860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY153_16860	COG3453	Protein conserved in bacteria
FY153_16865	COG0640	Transcriptional regulator
FY153_16875	COG2391	methyltransferase activity
FY153_16880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY153_16890	COG0022	dehydrogenase e1 component
FY153_16900	COG1960	acyl-CoA dehydrogenase activity
FY153_16905	COG0183	Belongs to the thiolase family
FY153_16915	COG1960	acyl-CoA dehydrogenase activity
FY153_16920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY153_16940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY153_16945	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY153_16950	COG4952	isomerase
FY153_16955	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_16955	COG3347	Dehydrogenase
FY153_16960	COG1349	DNA-binding transcription factor activity
FY153_16975	COG1129	ABC transporter
FY153_16980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_16985	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_16990	COG3254	rhamnose metabolic process
FY153_17005	COG2264	protein methyltransferase activity
FY153_17010	COG5001	Diguanylate cyclase
FY153_17025	COG4335	DNA alkylation repair
FY153_17030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY153_17035	COG4208	sulfate ABC transporter
FY153_17045	COG4150	thiosulfate binding
FY153_17050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY153_17065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY153_17075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY153_17085	COG1040	competence protein
FY153_17090	COG2226	methyltransferase
FY153_17105	COG0494	nUDIX hydrolase
FY153_17115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY153_17120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY153_17125	COG0653	protein targeting
FY153_17130	COG0697	spore germination
FY153_17195	COG2244	polysaccharide biosynthetic process
FY153_17210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY153_17220	COG0489	protein tyrosine kinase activity
FY153_17220	COG3206	protein involved in exopolysaccharide biosynthesis
FY153_17240	COG0438	transferase activity, transferring glycosyl groups
FY153_17245	COG0438	transferase activity, transferring glycosyl groups
FY153_17260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY153_17265	COG2273	Hydrolase Family 16
FY153_17265	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY153_17280	COG3842	ATPase activity
FY153_17285	COG3833	ABC-type maltose transport systems, permease component
FY153_17340	COG1396	sequence-specific DNA binding
FY153_17350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY153_17355	COG1129	ABC transporter
FY153_17360	COG4214	carbohydrate transport
FY153_17365	COG4213	ABC transporter substrate-binding protein
FY153_17380	COG0346	lactoylglutathione lyase activity
FY153_17385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY153_17385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY153_17390	COG4770	biotin carboxylase activity
FY153_17405	COG0625	glutathione transferase activity
FY153_17410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY153_17415	COG1396	sequence-specific DNA binding
FY153_17415	COG3800	Transcriptional regulator
FY153_17425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY153_17435	COG0300	oxidoreductase activity
FY153_17445	COG2096	Adenosyltransferase
FY153_17455	COG2086	electron transfer activity
FY153_17465	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY153_17475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY153_17480	COG0165	Argininosuccinate lyase
FY153_17515	COG2884	Cell division ATP-binding protein ftsE
FY153_17535	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY153_17545	COG0287	Prephenate dehydrogenase
FY153_17550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY153_17555	COG2226	methyltransferase
FY153_17560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY153_17580	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY153_17585	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY153_17625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY153_17630	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY153_17640	COG4974	Belongs to the 'phage' integrase family
FY153_17645	COG0825	malonyl-CoA metabolic process
FY153_17650	COG3034	peptidoglycan biosynthetic process
FY153_17655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY153_17655	COG0425	Belongs to the sulfur carrier protein TusA family
FY153_17660	COG0523	cobalamin synthesis protein
FY153_17665	COG1686	Belongs to the peptidase S11 family
FY153_17670	COG1473	amidohydrolase
FY153_17680	COG4953	penicillin-binding protein 1C
FY153_17685	COG2373	Large extracellular alpha-helical protein
FY153_17690	COG2835	tetraacyldisaccharide 4'-kinase activity
FY153_17725	COG0482	sulfurtransferase activity
FY153_17740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY153_17755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY153_17760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY153_17765	COG0037	tRNA processing
FY153_17775	COG2885	chlorophyll binding
FY153_17780	COG0823	Involved in the tonB-independent uptake of proteins
FY153_17800	COG0824	Thioesterase
FY153_17810	COG0494	nUDIX hydrolase
FY153_17825	COG2255	four-way junction helicase activity
FY153_17830	COG0632	four-way junction helicase activity
FY153_17835	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY153_17840	COG2972	Histidine kinase
FY153_17840	COG0840	transmembrane signaling receptor activity
FY153_17845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_17850	COG0217	transcriptional regulatory protein
FY153_17865	COG1692	metallophosphoesterase
FY153_17875	COG1253	flavin adenine dinucleotide binding
FY153_17915	COG0126	phosphoglycerate kinase activity
FY153_17920	COG3588	fructose-bisphosphate aldolase
FY153_17940	COG0254	rRNA binding
FY153_17945	COG1132	(ABC) transporter
FY153_17965	COG0483	inositol monophosphate 1-phosphatase activity
FY153_17995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY153_18000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY153_18005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY153_18010	COG0457	Tetratricopeptide repeat
FY153_18015	COG3750	Belongs to the UPF0335 family
FY153_18035	COG0469	pyruvate kinase activity
FY153_18040	COG3108	Peptidase M15
FY153_18050	COG1164	Oligoendopeptidase f
FY153_18055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY153_18065	COG5310	Homospermidine synthase
FY153_18075	COG0737	Belongs to the 5'-nucleotidase family
FY153_18080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY153_18085	COG0330	HflC and HflK could
FY153_18115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY153_18120	COG2951	lytic endotransglycosylase activity
FY153_18130	COG0745	RESPONSE REGULATOR receiver
FY153_18135	COG2205	protein histidine kinase activity
FY153_18150	COG0067	glutamate synthase
FY153_18150	COG0069	glutamate synthase activity
FY153_18150	COG0070	glutamate synthase
FY153_18165	COG2205	protein histidine kinase activity
FY153_18170	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY153_18175	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY153_18180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY153_18190	COG0252	asparaginase activity
FY153_18200	COG1027	Aspartate ammonia-lyase
FY153_18205	COG2186	Transcriptional regulator
FY153_18225	COG1309	transcriptional regulator
FY153_18245	COG4176	ABC-type proline glycine betaine transport system permease component
FY153_18250	COG4175	Glycine betaine
FY153_18250	COG3448	diguanylate cyclase activity
FY153_18255	COG2986	histidine ammonia-lyase
FY153_18260	COG1609	Transcriptional regulator
FY153_18280	COG1082	Xylose isomerase domain protein TIM barrel
FY153_18285	COG0673	inositol 2-dehydrogenase activity
FY153_18290	COG1082	Xylose isomerase domain protein TIM barrel
FY153_18295	COG1082	Xylose isomerase domain protein TIM barrel
FY153_18320	COG0732	type I restriction modification DNA specificity domain
FY153_18325	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FY153_18345	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY153_18370	COG1078	dGTPase activity
FY153_18380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_18390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_18395	COG0601	transmembrane transport
FY153_18400	COG0747	negative chemotaxis
FY153_18410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY153_18415	COG1454	alcohol dehydrogenase
FY153_18455	COG2307	Protein conserved in bacteria
FY153_18455	COG2308	Evidence 4 Homologs of previously reported genes of
FY153_18470	COG0488	(ABC) transporter
FY153_18475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY153_18480	COG2186	Transcriptional regulator
FY153_18495	COG1175	transmembrane transport
FY153_18500	COG0395	ABC-type sugar transport system, permease component
FY153_18510	COG3842	ATPase activity
FY153_18535	COG1304	FMN binding
FY153_18550	COG1063	alcohol dehydrogenase
FY153_18555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY153_18560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_18570	COG0765	amino acid transport
FY153_18575	COG0765	amino acid transport
FY153_18580	COG4221	oxidoreductase activity
FY153_18585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY153_18590	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_18595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY153_18610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY153_18625	COG0697	spore germination
FY153_18630	COG0697	spore germination
FY153_18635	COG0511	ligase activity, forming carbon-carbon bonds
FY153_18640	COG0439	Biotin carboxylase
FY153_18650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY153_18655	COG1984	allophanate hydrolase subunit 2
FY153_18660	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY153_18665	COG3842	ATPase activity
FY153_18675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY153_18685	COG0436	Aminotransferase
FY153_18700	COG0840	transmembrane signaling receptor activity
FY153_18700	COG2972	Histidine kinase
FY153_18705	COG1070	Carbohydrate kinase
FY153_18710	COG1830	Aldolase
FY153_18715	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY153_18720	COG0667	Aldo Keto reductase
FY153_18730	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_18735	COG1129	ABC transporter
FY153_18740	COG1879	ABC-type sugar transport system periplasmic component
FY153_18785	COG0071	Belongs to the small heat shock protein (HSP20) family
FY153_18800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY153_18815	COG0395	ABC-type sugar transport system, permease component
FY153_18830	COG3842	ATPase activity
FY153_18845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY153_18845	COG1648	precorrin-2 dehydrogenase activity
FY153_18850	COG0243	molybdopterin cofactor binding
FY153_18860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY153_18865	COG1116	anion transmembrane transporter activity
FY153_18870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_18875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY153_18885	COG3707	response regulator
FY153_18890	COG1802	Transcriptional regulator
FY153_18895	COG1914	H( )-stimulated, divalent metal cation uptake system
FY153_18900	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY153_18905	COG4336	lyase activity
FY153_18910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY153_18915	COG4770	biotin carboxylase activity
FY153_18920	COG0366	Alpha amylase catalytic
FY153_18930	COG4771	TonB-dependent receptor
FY153_18935	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY153_18955	COG1414	Transcriptional regulator
FY153_18960	COG1475	DNA binding
FY153_18965	COG1192	Involved in chromosome partitioning
FY153_18995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY153_19005	COG2986	histidine ammonia-lyase
FY153_19010	COG1228	amidohydrolase
FY153_19015	COG0402	S-adenosylhomocysteine deaminase activity
FY153_19065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY153_19075	COG1280	lysine exporter protein (LysE YggA)
FY153_19090	COG1309	transcriptional regulator
FY153_19095	COG4221	oxidoreductase activity
FY153_19100	COG1902	pentaerythritol trinitrate reductase activity
FY153_19105	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_19110	COG2267	carboxylic ester hydrolase activity
FY153_19140	COG1278	Cold shock
FY153_19160	COG0753	catalase activity
FY153_19185	COG3920	Histidine kinase
FY153_19190	COG1280	lysine exporter protein (LysE YggA)
FY153_19210	COG0583	DNA-binding transcription factor activity
FY153_19245	COG0583	DNA-binding transcription factor activity
FY153_19255	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_19260	COG1846	Transcriptional regulator
FY153_19280	COG2186	Transcriptional regulator
FY153_19290	COG1126	abc transporter atp-binding protein
FY153_19300	COG0765	amino acid transport
FY153_19305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_19320	COG0436	Aminotransferase
FY153_19325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_19355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY153_19360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_19365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_19375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_19380	COG0747	negative chemotaxis
FY153_19385	COG0747	negative chemotaxis
FY153_19395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_19405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_19415	COG1129	ABC transporter
FY153_19420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_19425	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_19450	COG0667	Aldo Keto reductase
FY153_19465	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_19470	COG1129	ABC transporter
FY153_19475	COG4213	ABC transporter substrate-binding protein
FY153_19495	COG4608	Belongs to the ABC transporter superfamily
FY153_19500	COG0444	Belongs to the ABC transporter superfamily
FY153_19505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_19510	COG0601	transmembrane transport
FY153_19515	COG0747	negative chemotaxis
FY153_19540	COG0765	amino acid transport
FY153_19545	COG4597	amino acid ABC transporter
FY153_19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_19565	COG3177	Filamentation induced by cAMP protein fic
FY153_19590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_19620	COG3209	COG3209 Rhs family protein
FY153_19640	COG0745	RESPONSE REGULATOR receiver
FY153_19650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_19655	COG1136	(ABC) transporter
FY153_19655	COG0577	efflux transmembrane transporter activity
FY153_19665	COG1733	regulation of RNA biosynthetic process
FY153_19700	COG0534	Mate efflux family protein
FY153_19715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY153_19720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY153_19730	COG1566	PFAM secretion protein HlyD family protein
FY153_19740	COG0625	glutathione transferase activity
FY153_19745	COG4221	oxidoreductase activity
FY153_19750	COG4172	Belongs to the ABC transporter superfamily
FY153_19755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_19760	COG0601	transmembrane transport
FY153_19765	COG4166	transmembrane transport
FY153_19770	COG0395	ABC-type sugar transport system, permease component
FY153_19785	COG1566	PFAM secretion protein HlyD family protein
FY153_19800	COG2207	Transcriptional regulator
FY153_19805	COG1309	transcriptional regulator
FY153_19810	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_19835	COG1846	Transcriptional regulator
FY153_19840	COG0583	DNA-binding transcription factor activity
FY153_19845	COG2828	Protein conserved in bacteria
FY153_19860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_19875	COG0840	transmembrane signaling receptor activity
FY153_19895	COG1215	transferase activity, transferring glycosyl groups
FY153_19925	COG0583	DNA-binding transcription factor activity
FY153_19930	COG0346	lactoylglutathione lyase activity
FY153_19945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY153_19965	COG0583	DNA-binding transcription factor activity
FY153_19970	COG0477	Major facilitator Superfamily
FY153_19980	COG2205	protein histidine kinase activity
FY153_19985	COG0745	RESPONSE REGULATOR receiver
FY153_19990	COG0671	phosphoesterase, PA-phosphatase related
FY153_20040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY153_20045	COG0156	8-amino-7-oxononanoate synthase activity
FY153_20050	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY153_20055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY153_20060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY153_20075	COG0010	Belongs to the arginase family
FY153_20085	COG0697	spore germination
FY153_20090	COG0673	inositol 2-dehydrogenase activity
FY153_20115	COG0477	Major facilitator Superfamily
FY153_20130	COG2194	sulfuric ester hydrolase activity
FY153_20140	COG0583	DNA-binding transcription factor activity
FY153_20145	COG4774	siderophore transport
FY153_20160	COG1120	ATPase activity
FY153_20170	COG3474	cytochrome
FY153_20175	COG2137	regulation of response to DNA damage stimulus
FY153_20180	COG3386	PFAM SMP-30 Gluconolaconase
FY153_20190	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_20195	COG1129	ABC transporter
FY153_20200	COG1879	ABC-type sugar transport system periplasmic component
FY153_20205	COG4585	Histidine kinase
FY153_20210	COG2197	response regulator
FY153_20220	COG2133	pyrroloquinoline quinone binding
FY153_20230	COG0500	methyltransferase
FY153_20235	COG0564	pseudouridine synthase activity
FY153_20250	COG3448	diguanylate cyclase activity
FY153_20250	COG4175	Glycine betaine
FY153_20255	COG4176	ABC-type proline glycine betaine transport system permease component
FY153_20270	COG4191	Histidine kinase
FY153_20270	COG0784	Response regulator, receiver
FY153_20275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY153_20280	COG3206	protein involved in exopolysaccharide biosynthesis
FY153_20280	COG0489	protein tyrosine kinase activity
FY153_20285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY153_20290	COG1215	transferase activity, transferring glycosyl groups
FY153_20295	COG1215	transferase activity, transferring glycosyl groups
FY153_20300	COG1215	transferase activity, transferring glycosyl groups
FY153_20305	COG0438	transferase activity, transferring glycosyl groups
FY153_20310	COG2273	Hydrolase Family 16
FY153_20315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY153_20320	COG2244	polysaccharide biosynthetic process
FY153_20325	COG0463	Glycosyl transferase, family 2
FY153_20330	COG2327	Polysaccharide pyruvyl transferase
FY153_20335	COG1215	transferase activity, transferring glycosyl groups
FY153_20355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY153_20360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_20375	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY153_20375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY153_20405	COG1523	belongs to the glycosyl hydrolase 13 family
FY153_20410	COG0033	Phosphoglucomutase
FY153_20415	COG0297	glycogen (starch) synthase activity
FY153_20420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY153_20425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY153_20430	COG0058	SHG alpha-glucan phosphorylase activity
FY153_20445	COG1794	racemase activity, acting on amino acids and derivatives
FY153_20450	COG1522	sequence-specific DNA binding
FY153_20460	COG2084	Dehydrogenase
FY153_20465	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_20470	COG1063	alcohol dehydrogenase
FY153_20480	COG4988	ABC transporter
FY153_20485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY153_20495	COG1294	oxidase, subunit
FY153_20525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY153_20530	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY153_20560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY153_20565	COG0539	negative regulation of cytoplasmic translation
FY153_20595	COG4221	oxidoreductase activity
FY153_20605	COG0747	negative chemotaxis
FY153_20610	COG0601	transmembrane transport
FY153_20615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_20620	COG0444	Belongs to the ABC transporter superfamily
FY153_20625	COG4608	Belongs to the ABC transporter superfamily
FY153_20630	COG0246	Mannitol dehydrogenase
FY153_20645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_20690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY153_20695	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_20710	COG4993	Dehydrogenase
FY153_20715	COG3685	Protein conserved in bacteria
FY153_20745	COG0693	protein deglycase activity
FY153_20765	COG0189	ligase activity
FY153_20770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY153_20775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY153_20790	COG0435	Glutathione S-transferase
FY153_20795	COG0583	DNA-binding transcription factor activity
FY153_20800	COG1012	belongs to the aldehyde dehydrogenase family
FY153_20805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY153_20810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_20815	COG1116	anion transmembrane transporter activity
FY153_20825	COG1522	sequence-specific DNA binding
FY153_20840	COG0784	Response regulator, receiver
FY153_20850	COG3920	Histidine kinase
FY153_20860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY153_20875	COG0019	diaminopimelate decarboxylase activity
FY153_20890	COG0527	aspartate kinase activity
FY153_20900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY153_20905	COG2890	protein-(glutamine-N5) methyltransferase activity
FY153_20915	COG0542	response to heat
FY153_20920	COG1196	nuclear chromosome segregation
FY153_20920	COG0741	lytic transglycosylase activity
FY153_20920	COG0739	heme binding
FY153_20960	COG3609	addiction module antidote protein, CC2985 family
FY153_21065	COG2376	Dihydroxyacetone kinase
FY153_21070	COG1522	sequence-specific DNA binding
FY153_21090	COG0431	NADPH-dependent FMN reductase
FY153_21100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_21110	COG4172	Belongs to the ABC transporter superfamily
FY153_21115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_21135	COG0277	FAD linked oxidase domain protein
FY153_21155	COG0778	Nitroreductase
FY153_21185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY153_21210	COG2318	DinB family
FY153_21215	COG0583	DNA-binding transcription factor activity
FY153_21230	COG1335	isochorismatase
FY153_21255	COG3842	ATPase activity
FY153_21260	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_21265	COG1177	transmembrane transport
FY153_21270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY153_21280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY153_21295	COG1120	ATPase activity
FY153_21300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_21310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY153_21315	COG1629	transport
FY153_21315	COG4774	siderophore transport
FY153_21320	COG4702	Belongs to the UPF0303 family
FY153_21340	COG1024	Enoyl-CoA hydratase
FY153_21345	COG1012	belongs to the aldehyde dehydrogenase family
FY153_21350	COG1653	transport
FY153_21355	COG1175	transmembrane transport
FY153_21360	COG0395	ABC-type sugar transport system, permease component
FY153_21365	COG3842	ATPase activity
FY153_21390	COG3474	cytochrome
FY153_21395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY153_21400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY153_21405	COG1845	cytochrome c oxidase, subunit III
FY153_21430	COG0577	efflux transmembrane transporter activity
FY153_21430	COG1136	(ABC) transporter
FY153_21485	COG3842	ATPase activity
FY153_21495	COG1177	transmembrane transport
FY153_21500	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_21515	COG1940	carbohydrate kinase activity
FY153_21535	COG1069	ribulokinase activity
FY153_21540	COG1349	DNA-binding transcription factor activity
FY153_21545	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_21570	COG0395	ABC-type sugar transport system, permease component
FY153_21580	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_21595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY153_21600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY153_21610	COG0477	Major facilitator Superfamily
FY153_21650	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FY153_21660	COG1733	regulation of RNA biosynthetic process
FY153_21695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY153_21700	COG3938	Belongs to the proline racemase family
FY153_21705	COG4176	ABC-type proline glycine betaine transport system permease component
FY153_21715	COG3448	diguanylate cyclase activity
FY153_21715	COG4175	Glycine betaine
FY153_21725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_21730	COG1012	belongs to the aldehyde dehydrogenase family
FY153_21735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_21745	COG0047	phosphoribosylformylglycinamidine synthase activity
FY153_21750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_21760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY153_21760	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY153_21770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY153_21785	COG1309	transcriptional regulator
FY153_21800	COG1136	(ABC) transporter
FY153_21815	COG1063	alcohol dehydrogenase
FY153_21825	COG1879	ABC-type sugar transport system periplasmic component
FY153_21835	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_21855	COG0477	Major facilitator Superfamily
FY153_21985	COG3300	MHYT domain
FY153_21985	COG5001	Diguanylate cyclase
FY153_22010	COG1253	flavin adenine dinucleotide binding
FY153_22025	COG3842	ATPase activity
FY153_22030	COG0395	ABC-type sugar transport system, permease component
FY153_22035	COG1175	transmembrane transport
FY153_22040	COG1653	transport
FY153_22050	COG0673	inositol 2-dehydrogenase activity
FY153_22055	COG1609	Transcriptional regulator
FY153_22070	COG0583	DNA-binding transcription factor activity
FY153_22080	COG1879	ABC-type sugar transport system periplasmic component
FY153_22085	COG1129	ABC transporter
FY153_22090	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_22095	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_22100	COG1609	Transcriptional regulator
FY153_22110	COG0673	inositol 2-dehydrogenase activity
FY153_22170	COG0714	Associated with various cellular activities
FY153_22175	COG3256	nitric oxide reductase
FY153_22205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY153_22210	COG3189	MarR family transcriptional regulator
FY153_22220	COG0826	peptidase U32
FY153_22245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY153_22255	COG4459	periplasmic nitrate reductase
FY153_22270	COG0243	molybdopterin cofactor binding
FY153_22280	COG3005	denitrification pathway
FY153_22295	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_22300	COG1535	isochorismatase
FY153_22300	COG3433	isochorismatase activity
FY153_22305	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY153_22310	COG1169	isochorismate synthase
FY153_22320	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY153_22320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY153_22325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY153_22335	COG2375	cellular response to nickel ion
FY153_22345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_22350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_22360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_22370	COG1629	transport
FY153_22370	COG4774	siderophore transport
FY153_22375	COG1960	acyl-CoA dehydrogenase activity
FY153_22380	COG0583	DNA-binding transcription factor activity
FY153_22385	COG1609	Transcriptional regulator
FY153_22395	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_22415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY153_22420	COG0583	DNA-binding transcription factor activity
FY153_22425	COG2814	Major facilitator Superfamily
FY153_22430	COG1473	amidohydrolase
FY153_22435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY153_22445	COG0747	negative chemotaxis
FY153_22450	COG0601	transmembrane transport
FY153_22455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_22460	COG0444	Belongs to the ABC transporter superfamily
FY153_22465	COG4608	Belongs to the ABC transporter superfamily
FY153_22470	COG0583	DNA-binding transcription factor activity
FY153_22475	COG0747	negative chemotaxis
FY153_22485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_22490	COG0154	amidase activity
FY153_22495	COG0693	protein deglycase activity
FY153_22505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_22510	COG0601	transmembrane transport
FY153_22520	COG1473	amidohydrolase
FY153_22525	COG4172	Belongs to the ABC transporter superfamily
FY153_22530	COG2390	Transcriptional regulator
FY153_22540	COG1175	transmembrane transport
FY153_22545	COG0395	ABC-type sugar transport system, permease component
FY153_22570	COG1069	ribulokinase activity
FY153_22595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY153_22615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY153_22620	COG1414	Transcriptional regulator
FY153_22625	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_22635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY153_22640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY153_22645	COG1121	(ABC) transporter
FY153_22650	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY153_22660	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY153_22665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY153_22670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY153_22675	COG0471	metal ion transport
FY153_22675	COG3273	potassium ion transport
FY153_22680	COG1253	flavin adenine dinucleotide binding
FY153_22685	COG1309	transcriptional regulator
FY153_22705	COG1609	Transcriptional regulator
FY153_22710	COG1070	Carbohydrate kinase
FY153_22715	COG2115	Belongs to the xylose isomerase family
FY153_22725	COG0778	Nitroreductase
FY153_22730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY153_22735	COG2011	ABC-type metal ion transport system permease component
FY153_22745	COG3300	MHYT domain
FY153_22745	COG5001	Diguanylate cyclase
FY153_22750	COG1054	Belongs to the UPF0176 family
FY153_22760	COG2954	triphosphatase activity
FY153_22765	COG0800	Aldolase
FY153_22785	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY153_22820	COG0523	cobalamin synthesis protein
FY153_22830	COG1846	Transcriptional regulator
FY153_22835	COG1609	Transcriptional regulator
FY153_22840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY153_22850	COG3718	enzyme involved in inositol metabolism
FY153_22860	COG3962	Belongs to the TPP enzyme family
FY153_22865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_22880	COG0411	ABC transporter
FY153_22895	COG0683	leucine binding
FY153_22910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_22920	COG0747	negative chemotaxis
FY153_22925	COG4172	Belongs to the ABC transporter superfamily
FY153_22950	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY153_22955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY153_22965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_22970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_22975	COG0765	amino acid transport
FY153_22980	COG0765	amino acid transport
FY153_22985	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY153_22990	COG3485	protocatechuate 3,4-dioxygenase
FY153_22995	COG3485	protocatechuate 3,4-dioxygenase
FY153_23000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY153_23010	COG0583	DNA-binding transcription factor activity
FY153_23025	COG1414	Transcriptional regulator
FY153_23035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY153_23040	COG0183	Belongs to the thiolase family
FY153_23045	COG1609	Transcriptional regulator
FY153_23060	COG1082	Xylose isomerase domain protein TIM barrel
FY153_23065	COG0673	inositol 2-dehydrogenase activity
FY153_23075	COG1609	Transcriptional regulator
FY153_23080	COG0395	ABC-type sugar transport system, permease component
FY153_23085	COG1175	transmembrane transport
FY153_23090	COG3842	ATPase activity
FY153_23100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY153_23120	COG2814	Major facilitator Superfamily
FY153_23125	COG4774	siderophore transport
FY153_23130	COG3712	iron ion homeostasis
FY153_23140	COG1940	carbohydrate kinase activity
FY153_23145	COG0584	glycerophosphoryl diester phosphodiesterase
FY153_23150	COG0300	oxidoreductase activity
FY153_23165	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY153_23185	COG0667	Aldo Keto reductase
FY153_23190	COG0583	DNA-binding transcription factor activity
FY153_23200	COG1132	(ABC) transporter
FY153_23215	COG1216	Glycosyl transferase, family 2
FY153_23215	COG1442	glycosyl transferase family 8
FY153_23220	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY153_23230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY153_23245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY153_23250	COG3754	Rhamnan synthesis protein F
FY153_23265	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY153_23270	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY153_23275	COG1088	dTDP-glucose 4,6-dehydratase activity
FY153_23280	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY153_23285	COG0210	DNA helicase
FY153_23295	COG1609	Transcriptional regulator
FY153_23300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY153_23300	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY153_23315	COG0395	ABC-type sugar transport system, permease component
FY153_23320	COG3842	ATPase activity
FY153_23330	COG0444	Belongs to the ABC transporter superfamily
FY153_23335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_23340	COG0601	transmembrane transport
FY153_23365	COG5001	Diguanylate cyclase
FY153_23365	COG3300	MHYT domain
FY153_23370	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_23380	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY153_23390	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY153_23395	COG0306	phosphate transporter
FY153_23400	COG1392	Phosphate transport regulator
FY153_23415	COG1566	PFAM secretion protein HlyD family protein
FY153_23420	COG0745	RESPONSE REGULATOR receiver
FY153_23425	COG2205	protein histidine kinase activity
FY153_23440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY153_23450	COG4774	siderophore transport
FY153_23460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_23465	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_23470	COG1120	ATPase activity
FY153_23475	COG0583	DNA-binding transcription factor activity
FY153_23485	COG3119	arylsulfatase activity
FY153_23490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY153_23495	COG3842	ATPase activity
FY153_23500	COG0165	Argininosuccinate lyase
FY153_23505	COG0395	ABC-type sugar transport system, permease component
FY153_23510	COG1175	transmembrane transport
FY153_23515	COG2182	Extracellular solute-binding protein
FY153_23520	COG1940	carbohydrate kinase activity
FY153_23545	COG1486	melibiose metabolic process
FY153_23550	COG0747	negative chemotaxis
FY153_23555	COG0601	transmembrane transport
FY153_23560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_23565	COG4172	Belongs to the ABC transporter superfamily
FY153_23570	COG1486	melibiose metabolic process
FY153_23575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY153_23580	COG0842	Transport permease protein
FY153_23580	COG1129	ABC transporter
FY153_23585	COG0842	Transport permease protein
FY153_23605	COG0784	Response regulator, receiver
FY153_23610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY153_23620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_23625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY153_23640	COG0765	amino acid transport
FY153_23650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_23660	COG3938	Belongs to the proline racemase family
FY153_23675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_23680	COG0765	amino acid transport
FY153_23685	COG0765	amino acid transport
FY153_23695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY153_23710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY153_23730	COG3383	formate dehydrogenase (NAD+) activity
FY153_23740	COG2223	nitrite transmembrane transporter activity
FY153_23745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY153_23755	COG2186	Transcriptional regulator
FY153_23760	COG0747	negative chemotaxis
FY153_23765	COG0601	transmembrane transport
FY153_23770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_23775	COG4172	Belongs to the ABC transporter superfamily
FY153_23780	COG4948	Mandelate Racemase Muconate Lactonizing
FY153_23790	COG2186	Transcriptional regulator
FY153_23795	COG0747	negative chemotaxis
FY153_23800	COG0601	transmembrane transport
FY153_23805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_23810	COG0405	Gamma-glutamyltransferase
FY153_23820	COG0483	inositol monophosphate 1-phosphatase activity
FY153_23830	COG3842	ATPase activity
FY153_23835	COG0395	ABC-type sugar transport system, permease component
FY153_23855	COG3237	CsbD-like
FY153_23865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY153_23870	COG3181	Tripartite tricarboxylate transporter family receptor
FY153_23875	COG5265	(ABC) transporter
FY153_23880	COG0488	(ABC) transporter
FY153_23905	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY153_23910	COG0110	maltose O-acetyltransferase activity
FY153_23920	COG1063	alcohol dehydrogenase
FY153_23925	COG3284	Transcriptional regulator
FY153_23945	COG1129	ABC transporter
FY153_23950	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_23955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_23965	COG0572	uridine kinase
FY153_23970	COG1082	Xylose isomerase domain protein TIM barrel
FY153_23995	COG4178	(ABC) transporter
FY153_24030	COG0640	Transcriptional regulator
FY153_24045	COG2274	protein secretion by the type I secretion system
FY153_24060	COG1192	Involved in chromosome partitioning
FY153_24065	COG1475	DNA binding
FY153_24070	COG0640	Transcriptional regulator
FY153_24085	COG1126	abc transporter atp-binding protein
FY153_24090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY153_24095	COG1609	Transcriptional regulator
FY153_24130	COG3239	Fatty acid desaturase
FY153_24140	COG1278	Cold shock
FY153_24215	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY153_24215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY153_24250	COG4191	Histidine kinase
FY153_24255	COG1132	(ABC) transporter
FY153_24265	COG0640	Transcriptional regulator
FY153_24295	COG4977	sequence-specific DNA binding
FY153_24300	COG2211	Major facilitator Superfamily
FY153_24305	COG2807	transmembrane transport
FY153_24310	COG1846	Transcriptional regulator
FY153_24325	COG2814	Major facilitator Superfamily
FY153_24355	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY153_24370	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY153_24375	COG0583	DNA-binding transcription factor activity
FY153_24390	COG0071	Belongs to the small heat shock protein (HSP20) family
FY153_24435	COG3838	Conjugal transfer protein Trbc
FY153_24440	COG3702	type iv secretory pathway
FY153_24445	COG3451	type IV secretory pathway VirB4
FY153_24460	COG3704	protein secretion by the type IV secretion system
FY153_24470	COG3736	Type IV secretory pathway, component VirB8
FY153_24475	COG3504	Conjugal transfer protein
FY153_24480	COG2948	multi-organism process
FY153_24485	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY153_24585	COG3831	ATPase activity
FY153_24600	COG3505	Type IV secretory pathway VirD4
FY153_24625	COG0583	DNA-binding transcription factor activity
FY153_24665	COG0745	RESPONSE REGULATOR receiver
FY153_24705	COG3842	ATPase activity
FY153_24710	COG4208	sulfate ABC transporter
FY153_24715	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_24735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY153_24740	COG1942	4-Oxalocrotonate Tautomerase
FY153_24750	COG3971	2-oxopent-4-enoate hydratase activity
FY153_24760	COG1414	Transcriptional regulator
FY153_24770	COG1137	ATPase activity
FY153_24785	COG4177	L-phenylalanine transmembrane transporter activity
FY153_24805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY153_24810	COG1175	transmembrane transport
FY153_24815	COG0395	ABC-type sugar transport system, permease component
FY153_24825	COG0366	Alpha amylase catalytic
FY153_24830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY153_24835	COG1082	Xylose isomerase domain protein TIM barrel
FY153_24840	COG3842	ATPase activity
FY153_24850	COG1940	carbohydrate kinase activity
FY153_24855	COG0395	ABC-type sugar transport system, permease component
FY153_24865	COG2182	Extracellular solute-binding protein
FY153_24870	COG0673	inositol 2-dehydrogenase activity
FY153_24900	COG1126	abc transporter atp-binding protein
FY153_24905	COG0765	amino acid transport
FY153_24910	COG0765	amino acid transport
FY153_24920	COG4608	Belongs to the ABC transporter superfamily
FY153_24930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_24945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY153_24950	COG0583	DNA-binding transcription factor activity
FY153_24955	COG2423	ornithine cyclodeaminase activity
FY153_24965	COG1957	nucleoside hydrolase
FY153_24980	COG1335	isochorismatase
FY153_24985	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_25030	COG0583	DNA-binding transcription factor activity
FY153_25035	COG1902	pentaerythritol trinitrate reductase activity
FY153_25040	COG0583	DNA-binding transcription factor activity
FY153_25045	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_25055	COG1335	isochorismatase
FY153_25060	COG0583	DNA-binding transcription factor activity
FY153_25070	COG1695	Transcriptional regulator
FY153_25150	COG2207	Transcriptional regulator
FY153_25195	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_25210	COG1802	Transcriptional regulator
FY153_25215	COG3485	protocatechuate 3,4-dioxygenase
FY153_25220	COG3971	2-oxopent-4-enoate hydratase activity
FY153_25235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY153_25240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY153_25255	COG1063	alcohol dehydrogenase
FY153_25265	COG1960	acyl-CoA dehydrogenase activity
FY153_25270	COG1024	Enoyl-CoA hydratase
FY153_25280	COG1012	belongs to the aldehyde dehydrogenase family
FY153_25285	COG0477	Major facilitator Superfamily
FY153_25300	COG3706	GGDEF domain
FY153_25320	COG1846	Transcriptional regulator
FY153_25360	COG1012	belongs to the aldehyde dehydrogenase family
FY153_25370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY153_25380	COG3386	PFAM SMP-30 Gluconolaconase
FY153_25385	COG3622	Belongs to the hyi family
FY153_25390	COG2084	Dehydrogenase
FY153_25415	COG1940	carbohydrate kinase activity
FY153_25420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_25430	COG1129	ABC transporter
FY153_25450	COG0583	DNA-binding transcription factor activity
FY153_25455	COG2271	Major facilitator Superfamily
FY153_25465	COG2272	Belongs to the type-B carboxylesterase lipase family
FY153_25485	COG1129	ABC transporter
FY153_25510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY153_25520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY153_25555	COG0583	DNA-binding transcription factor activity
FY153_25560	COG1414	Transcriptional regulator
FY153_25570	COG4948	Mandelate Racemase Muconate Lactonizing
FY153_25580	COG3842	ATPase activity
FY153_25585	COG1175	transmembrane transport
FY153_25590	COG0395	ABC-type sugar transport system, permease component
FY153_25600	COG0477	Major facilitator Superfamily
FY153_25635	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY153_25655	COG0747	negative chemotaxis
FY153_25665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_25680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_25690	COG4215	(ABC) transporter
FY153_25745	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY153_25750	COG0251	oxidation-reduction process
FY153_25755	COG3547	Transposase (IS116 IS110 IS902 family)
FY153_25790	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_25795	COG1335	isochorismatase
FY153_25805	COG1309	transcriptional regulator
FY153_25810	COG4604	ABC transporter, ATP-binding protein
FY153_25815	COG4605	iron ion homeostasis
FY153_25820	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY153_25830	COG2132	Multicopper oxidase
FY153_25835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY153_25840	COG4771	TonB-dependent receptor
FY153_25875	COG1695	Transcriptional regulator
FY153_25910	COG2132	Multicopper oxidase
FY153_25945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY153_25965	COG1192	Involved in chromosome partitioning
FY153_25970	COG1475	DNA binding
FY153_25975	COG0640	Transcriptional regulator
FY153_25980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY153_26025	COG0583	DNA-binding transcription factor activity
FY153_26035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY153_26040	COG1116	anion transmembrane transporter activity
FY153_26045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY153_26055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_26060	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_26090	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY153_26095	COG1129	ABC transporter
FY153_26120	COG4172	Belongs to the ABC transporter superfamily
FY153_26125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_26130	COG0601	transmembrane transport
FY153_26140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_26145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY153_26150	COG0583	DNA-binding transcription factor activity
FY153_26160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY153_26175	COG1132	(ABC) transporter
FY153_26180	COG4172	Belongs to the ABC transporter superfamily
FY153_26185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_26205	COG1082	Xylose isomerase domain protein TIM barrel
FY153_26210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY153_26215	COG0019	diaminopimelate decarboxylase activity
FY153_26225	COG1475	DNA binding
FY153_26235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY153_26330	COG1475	DNA binding
FY153_26355	COG2824	Alkylphosphonate utilization operon protein PhnA
FY153_26405	COG5489	Protein of unknown function (DUF736)
FY153_26490	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY153_26505	COG0747	negative chemotaxis
FY153_26510	COG0444	Belongs to the ABC transporter superfamily
FY153_26525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_26530	COG0584	glycerophosphoryl diester phosphodiesterase
FY153_26535	COG0483	inositol monophosphate 1-phosphatase activity
FY153_26600	COG3161	chorismate lyase activity
FY153_26750	COG3436	PFAM IS66 Orf2 family protein
FY153_26830	COG2222	sugar isomerase
FY153_26840	COG0006	proline dipeptidase activity
FY153_26860	COG1177	transmembrane transport
FY153_26865	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY153_26870	COG3842	ATPase activity
FY153_26900	COG3842	ATPase activity
FY153_26905	COG0006	proline dipeptidase activity
FY153_26925	COG0300	oxidoreductase activity
FY153_26930	COG0129	dihydroxy-acid dehydratase activity
FY153_26935	COG0667	Aldo Keto reductase
FY153_26945	COG1028	Short-chain dehydrogenase reductase Sdr
FY153_26955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_26960	COG0601	transmembrane transport
FY153_26965	COG4172	Belongs to the ABC transporter superfamily
FY153_26975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY153_27010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY153_27045	COG3701	Conjugal transfer protein
FY153_27050	COG3846	protein secretion by the type IV secretion system
FY153_27060	COG5314	conjugation
FY153_27065	COG3451	type IV secretory pathway VirB4
FY153_27080	COG4962	Type ii secretion system protein e