locus-tag	class	description
FY154_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY154_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY154_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY154_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY154_00025	COG1420	regulation of RNA biosynthetic process
FY154_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY154_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY154_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY154_00050	COG1137	ATPase activity
FY154_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY154_00065	COG0616	signal peptide processing
FY154_00070	COG0776	regulation of translation
FY154_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY154_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY154_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY154_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY154_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY154_00115	COG0728	peptidoglycan biosynthetic process
FY154_00125	COG0180	Tryptophanyl-tRNA synthetase
FY154_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY154_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY154_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY154_00165	COG1702	phosphate starvation-inducible protein PhoH
FY154_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY154_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY154_00185	COG1396	sequence-specific DNA binding
FY154_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY154_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY154_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_00210	COG0242	peptide deformylase activity
FY154_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY154_00220	COG0101	tRNA pseudouridine synthase activity
FY154_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY154_00235	COG2171	N-acyltransferase activity
FY154_00245	COG0840	transmembrane signaling receptor activity
FY154_00250	COG1957	nucleoside hydrolase
FY154_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY154_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY154_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY154_00295	COG0706	membrane insertase activity
FY154_00300	COG0594	ribonuclease P activity
FY154_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY154_00310	COG0840	transmembrane signaling receptor activity
FY154_00325	COG2226	methyltransferase
FY154_00330	COG3842	ATPase activity
FY154_00335	COG1175	transmembrane transport
FY154_00340	COG0395	ABC-type sugar transport system, permease component
FY154_00355	COG0427	acetyl-CoA hydrolase
FY154_00365	COG3938	Belongs to the proline racemase family
FY154_00370	COG0418	dihydroorotase activity
FY154_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY154_00400	COG0166	Belongs to the GPI family
FY154_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY154_00410	COG3842	ATPase activity
FY154_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY154_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY154_00425	COG4774	siderophore transport
FY154_00470	COG2326	polyphosphate kinase activity
FY154_00475	COG5002	protein histidine kinase activity
FY154_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY154_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY154_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY154_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY154_00505	COG0745	RESPONSE REGULATOR receiver
FY154_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY154_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY154_00530	COG2967	ApaG domain
FY154_00545	COG0717	Belongs to the dCTP deaminase family
FY154_00555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY154_00605	COG0167	dihydroorotate dehydrogenase activity
FY154_00620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY154_00640	COG1959	2 iron, 2 sulfur cluster binding
FY154_00645	COG1201	RNA secondary structure unwinding
FY154_00675	COG1960	acyl-CoA dehydrogenase activity
FY154_00680	COG0183	Belongs to the thiolase family
FY154_00685	COG1024	Enoyl-CoA hydratase
FY154_00685	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY154_00785	COG0582	viral genome integration into host DNA
FY154_00810	COG1320	monovalent cation:proton antiporter activity
FY154_00815	COG2212	antiporter activity
FY154_00820	COG1863	multisubunit Na H antiporter MnhE subunit
FY154_00825	COG0651	ATP synthesis coupled electron transport
FY154_00830	COG1006	Multisubunit Na H antiporter MnhC subunit
FY154_00835	COG2111	Na H antiporter
FY154_00835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY154_00845	COG0840	transmembrane signaling receptor activity
FY154_00855	COG0745	RESPONSE REGULATOR receiver
FY154_00860	COG2198	Histidine kinase
FY154_00860	COG0643	Histidine kinase
FY154_00865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY154_00870	COG2201	protein-glutamate methylesterase activity
FY154_00875	COG0745	RESPONSE REGULATOR receiver
FY154_00880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY154_00890	COG1766	The M ring may be actively involved in energy transduction
FY154_00895	COG2771	luxR family
FY154_00905	COG2972	Histidine kinase
FY154_00905	COG0840	transmembrane signaling receptor activity
FY154_00910	COG2205	protein histidine kinase activity
FY154_00910	COG2198	Histidine kinase
FY154_00910	COG0784	Response regulator, receiver
FY154_00915	COG1970	mechanosensitive ion channel activity
FY154_00920	COG0436	Aminotransferase
FY154_00935	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY154_00940	COG0424	maF-like protein
FY154_00945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY154_00955	COG5328	Belongs to the UPF0262 family
FY154_00960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY154_00970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY154_00990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY154_01000	COG1338	Plays a role in the flagellum-specific transport system
FY154_01010	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY154_01020	COG1706	bacterial-type flagellum-dependent cell motility
FY154_01025	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY154_01030	COG4786	Flagellar basal body rod
FY154_01035	COG1677	Flagellar hook-basal body complex protein FliE
FY154_01040	COG1558	bacterial-type flagellum-dependent cell motility
FY154_01045	COG1815	bacterial-type flagellum-dependent cell motility
FY154_01055	COG1157	protein secretion by the type III secretion system
FY154_01060	COG4786	Flagellar basal body rod
FY154_01070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY154_01075	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY154_01080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY154_01085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY154_01090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY154_01110	COG1360	Flagellar Motor Protein
FY154_01135	COG1749	Flagellar hook protein flgE
FY154_01155	COG5443	negative regulation of bacterial-type flagellum assembly
FY154_01160	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY154_01170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY154_01210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY154_01215	COG1609	Transcriptional regulator
FY154_01220	COG1653	transport
FY154_01225	COG1175	transmembrane transport
FY154_01230	COG0395	ABC-type sugar transport system, permease component
FY154_01235	COG0366	Alpha amylase catalytic
FY154_01240	COG3842	ATPase activity
FY154_01255	COG0129	dihydroxy-acid dehydratase activity
FY154_01260	COG0363	glucosamine-6-phosphate deaminase activity
FY154_01265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY154_01270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_01280	COG2081	HI0933 family
FY154_01300	COG2224	Isocitrate lyase
FY154_01315	COG3842	ATPase activity
FY154_01320	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY154_01325	COG1177	transmembrane transport
FY154_01335	COG2205	protein histidine kinase activity
FY154_01345	COG0248	Ppx GppA phosphatase
FY154_01350	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY154_01355	COG0477	Major facilitator Superfamily
FY154_01385	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY154_01390	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY154_01400	COG0142	geranyltranstransferase activity
FY154_01425	COG0752	glycyl-tRNA synthetase alpha subunit
FY154_01435	COG1704	LemA family
FY154_01440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY154_01450	COG0751	glycine-tRNA ligase activity
FY154_01455	COG1683	Conserved Protein
FY154_01460	COG0840	transmembrane signaling receptor activity
FY154_01470	COG0151	Belongs to the GarS family
FY154_01475	COG2183	response to ionizing radiation
FY154_01480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY154_01505	COG0583	DNA-binding transcription factor activity
FY154_01525	COG0306	phosphate transporter
FY154_01535	COG0561	phosphatase activity
FY154_01540	COG0438	transferase activity, transferring glycosyl groups
FY154_01545	COG2186	Transcriptional regulator
FY154_01560	COG0583	DNA-binding transcription factor activity
FY154_01565	COG0277	FAD linked oxidase domain protein
FY154_01570	COG0277	FAD linked oxidase domain protein
FY154_01575	COG0247	lactate metabolic process
FY154_01585	COG1376	ErfK ybiS ycfS ynhG family protein
FY154_01590	COG2818	Glycosylase
FY154_01600	COG2855	membrane
FY154_01605	COG0583	DNA-binding transcription factor activity
FY154_01635	COG0124	histidyl-tRNA synthetase
FY154_01645	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY154_01650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY154_01655	COG2259	Doxx family
FY154_01665	COG0459	protein refolding
FY154_01670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY154_01680	COG0196	riboflavin kinase activity
FY154_01685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY154_01695	COG0590	tRNA wobble adenosine to inosine editing
FY154_01700	COG1187	pseudouridine synthase activity
FY154_01705	COG0742	ribosomal rna small subunit methyltransferase
FY154_01710	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY154_01720	COG0312	modulator of DNA gyrase
FY154_01725	COG0483	inositol monophosphate 1-phosphatase activity
FY154_01735	COG1519	Transferase
FY154_01745	COG1663	tetraacyldisaccharide 4'-kinase activity
FY154_01755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY154_01760	COG0745	RESPONSE REGULATOR receiver
FY154_01765	COG5001	Diguanylate cyclase
FY154_01765	COG3300	MHYT domain
FY154_01770	COG3386	PFAM SMP-30 Gluconolaconase
FY154_01775	COG0800	Aldolase
FY154_01780	COG3734	2-keto-3-deoxy-galactonokinase
FY154_01785	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_01790	COG1414	Transcriptional regulator
FY154_01795	COG2197	response regulator
FY154_01810	COG0598	Magnesium transport protein CorA
FY154_01815	COG3158	transport of potassium into the cell
FY154_01830	COG0356	it plays a direct role in the translocation of protons across the membrane
FY154_01840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY154_01845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY154_01860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY154_01880	COG0009	L-threonylcarbamoyladenylate synthase
FY154_01890	COG4638	Rieske (2fe-2S)
FY154_01915	COG1960	acyl-CoA dehydrogenase activity
FY154_01930	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY154_01935	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY154_01940	COG0840	transmembrane signaling receptor activity
FY154_01950	COG1522	sequence-specific DNA binding
FY154_01975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY154_01980	COG1741	Belongs to the pirin family
FY154_01985	COG1722	exodeoxyribonuclease VII activity
FY154_01990	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY154_01995	COG1268	BioY protein
FY154_02000	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY154_02005	COG1122	ATPase activity
FY154_02010	COG3214	Protein conserved in bacteria
FY154_02015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY154_02015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY154_02020	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY154_02035	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY154_02050	COG0259	pyridoxamine-phosphate oxidase activity
FY154_02080	COG0312	modulator of DNA gyrase
FY154_02095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY154_02100	COG0109	protoheme IX farnesyltransferase activity
FY154_02105	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY154_02120	COG3346	SURF1 family
FY154_02125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY154_02130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY154_02135	COG0328	RNA-DNA hybrid ribonuclease activity
FY154_02145	COG0678	peroxiredoxin activity
FY154_02145	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY154_02155	COG1678	Uncharacterized ACR, COG1678
FY154_02160	COG3237	CsbD-like
FY154_02170	COG3300	MHYT domain
FY154_02170	COG5001	Diguanylate cyclase
FY154_02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY154_02180	COG0612	Peptidase, M16
FY154_02205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY154_02210	COG1802	Transcriptional regulator
FY154_02230	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY154_02235	COG3609	addiction module antidote protein, CC2985 family
FY154_02240	COG3668	Plasmid stabilization system
FY154_02250	COG1194	a g-specific adenine glycosylase
FY154_02265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY154_02270	COG1196	nuclear chromosome segregation
FY154_02275	COG2514	catechol 2,3-dioxygenase activity
FY154_02280	COG0574	Belongs to the PEP-utilizing enzyme family
FY154_02280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY154_02295	COG1823	symporter activity
FY154_02320	COG0579	oxidoreductase
FY154_02335	COG2895	sulfate adenylyltransferase (ATP) activity
FY154_02340	COG0175	sulfate reduction
FY154_02345	COG0175	sulfate reduction
FY154_02350	COG1959	2 iron, 2 sulfur cluster binding
FY154_02355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY154_02360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY154_02365	COG4208	sulfate ABC transporter
FY154_02370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY154_02380	COG2199	diguanylate cyclase activity
FY154_02380	COG2200	EAL domain
FY154_02380	COG2203	Gaf domain
FY154_02390	COG1309	transcriptional regulator
FY154_02395	COG1012	belongs to the aldehyde dehydrogenase family
FY154_02400	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY154_02430	COG0625	glutathione transferase activity
FY154_02440	COG0477	Major facilitator Superfamily
FY154_02450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY154_02450	COG1793	dna ligase
FY154_02470	COG1376	ErfK ybiS ycfS ynhG family protein
FY154_02475	COG1376	ErfK ybiS ycfS ynhG family protein
FY154_02480	COG1846	Transcriptional regulator
FY154_02485	COG1764	response to oxidative stress
FY154_02500	COG0488	(ABC) transporter
FY154_02540	COG4221	oxidoreductase activity
FY154_02555	COG0433	COG0433 Predicted ATPase
FY154_02565	COG1733	regulation of RNA biosynthetic process
FY154_02570	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY154_02585	COG0656	L-ascorbic acid biosynthetic process
FY154_02590	COG3781	membrane
FY154_02595	COG2378	regulation of single-species biofilm formation
FY154_02605	COG4106	trans-aconitate 2-methyltransferase activity
FY154_02610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY154_02615	COG0840	transmembrane signaling receptor activity
FY154_02620	COG0583	DNA-binding transcription factor activity
FY154_02635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY154_02655	COG3909	cytochrome
FY154_02660	COG2010	Cytochrome c
FY154_02690	COG0789	Transcriptional regulator
FY154_02715	COG0517	IMP dehydrogenase activity
FY154_02715	COG4175	Glycine betaine
FY154_02720	COG4176	ABC-type proline glycine betaine transport system permease component
FY154_02740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_02750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY154_02750	COG2169	Transcriptional regulator
FY154_02760	COG2514	catechol 2,3-dioxygenase activity
FY154_02775	COG1272	protein, Hemolysin III
FY154_02785	COG1280	lysine exporter protein (LysE YggA)
FY154_02790	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY154_02795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY154_02795	COG2111	Na H antiporter
FY154_02800	COG2111	Na H antiporter
FY154_02805	COG1006	Multisubunit Na H antiporter MnhC subunit
FY154_02810	COG0651	ATP synthesis coupled electron transport
FY154_02815	COG1863	multisubunit Na H antiporter MnhE subunit
FY154_02820	COG2212	antiporter activity
FY154_02825	COG1320	monovalent cation:proton antiporter activity
FY154_02830	COG4957	zinc ion binding
FY154_02845	COG2166	iron-sulfur cluster assembly
FY154_02855	COG2205	protein histidine kinase activity
FY154_02900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY154_02905	COG2983	Belongs to the UPF0260 family
FY154_02915	COG3041	Addiction module toxin RelE StbE family
FY154_02920	COG3077	Addiction module antitoxin, RelB DinJ family
FY154_02925	COG2217	Heavy metal translocating P-type atpase
FY154_02960	COG1621	beta-fructofuranosidase activity
FY154_02965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY154_03015	COG4695	Portal protein
FY154_03120	COG4235	cytochrome complex assembly
FY154_03125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY154_03130	COG1138	Cytochrome C-type biogenesis protein
FY154_03135	COG3088	subunit of a heme lyase
FY154_03140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY154_03145	COG0745	RESPONSE REGULATOR receiver
FY154_03150	COG2205	protein histidine kinase activity
FY154_03155	COG3011	Protein conserved in bacteria
FY154_03160	COG3713	MltA-interacting MipA family protein
FY154_03165	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY154_03170	COG2202	Pas domain
FY154_03170	COG2205	protein histidine kinase activity
FY154_03180	COG0308	aminopeptidase N
FY154_03185	COG0697	spore germination
FY154_03200	COG0443	Heat shock 70 kDa protein
FY154_03235	COG0604	alcohol dehydrogenase
FY154_03240	COG1733	regulation of RNA biosynthetic process
FY154_03245	COG1968	undecaprenyl-diphosphatase activity
FY154_03250	COG2239	Acts as a magnesium transporter
FY154_03255	COG2814	Major facilitator Superfamily
FY154_03280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY154_03305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY154_03465	COG0741	lytic transglycosylase activity
FY154_03470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_03475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY154_03480	COG0840	transmembrane signaling receptor activity
FY154_03490	COG1758	RNA polymerase activity
FY154_03510	COG0736	holo-[acyl-carrier-protein] synthase activity
FY154_03515	COG0681	Belongs to the peptidase S26 family
FY154_03520	COG0571	ribonuclease III activity
FY154_03525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY154_03535	COG0784	Response regulator, receiver
FY154_03540	COG1381	Involved in DNA repair and RecF pathway recombination
FY154_03550	COG2226	methyltransferase
FY154_03560	COG1418	mRNA catabolic process
FY154_03570	COG0346	lactoylglutathione lyase activity
FY154_03585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_03590	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY154_03595	COG0668	transmembrane transport
FY154_03605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY154_03635	COG1742	UPF0060 membrane protein
FY154_03650	COG1183	phosphatidylcholine synthase activity
FY154_03655	COG0688	phosphatidylethanolamine metabolic process
FY154_03660	COG5265	(ABC) transporter
FY154_03700	COG2852	Protein conserved in bacteria
FY154_03705	COG0215	cysteine-tRNA ligase activity
FY154_03710	COG4221	oxidoreductase activity
FY154_03715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY154_03720	COG1286	toxin biosynthetic process
FY154_03740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY154_03750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY154_03760	COG5265	(ABC) transporter
FY154_03765	COG0305	Participates in initiation and elongation during chromosome replication
FY154_03785	COG0359	binds to the 23S rRNA
FY154_03795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY154_03800	COG0360	Binds together with S18 to 16S ribosomal RNA
FY154_03810	COG0667	Aldo Keto reductase
FY154_03815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY154_03825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY154_03830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY154_03840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY154_03845	COG1561	YicC-like family, N-terminal region
FY154_03850	COG0194	GDP metabolic process
FY154_03865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY154_03870	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY154_03880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY154_03895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY154_03920	COG3300	MHYT domain
FY154_03920	COG5001	Diguanylate cyclase
FY154_03925	COG4191	Histidine kinase
FY154_03930	COG4566	intracellular signal transduction
FY154_03940	COG0488	(ABC) transporter
FY154_03945	COG3706	GGDEF domain
FY154_03955	COG0105	UTP biosynthetic process
FY154_03975	COG0314	molybdopterin synthase activity
FY154_03985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY154_03990	COG0322	excinuclease ABC activity
FY154_03995	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_04010	COG3719	Belongs to the RNase T2 family
FY154_04020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY154_04025	COG0243	molybdopterin cofactor binding
FY154_04050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY154_04055	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY154_04065	COG0628	permease
FY154_04075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY154_04080	COG0248	Ppx GppA phosphatase
FY154_04105	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY154_04115	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY154_04120	COG0477	Major facilitator Superfamily
FY154_04125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY154_04135	COG0840	transmembrane signaling receptor activity
FY154_04140	COG0659	secondary active sulfate transmembrane transporter activity
FY154_04150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY154_04155	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY154_04165	COG0113	porphobilinogen synthase activity
FY154_04185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY154_04190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY154_04195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY154_04195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY154_04205	COG1280	lysine exporter protein (LysE YggA)
FY154_04210	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY154_04215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY154_04220	COG2814	Major facilitator Superfamily
FY154_04225	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY154_04245	COG0416	fatty acid biosynthetic process
FY154_04250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY154_04255	COG0776	regulation of translation
FY154_04290	COG0601	transmembrane transport
FY154_04295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_04300	COG0444	Belongs to the ABC transporter superfamily
FY154_04310	COG0747	negative chemotaxis
FY154_04320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY154_04325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY154_04340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY154_04345	COG0583	DNA-binding transcription factor activity
FY154_04350	COG0737	Belongs to the 5'-nucleotidase family
FY154_04370	COG2897	thiosulfate sulfurtransferase activity
FY154_04385	COG0415	Belongs to the DNA photolyase family
FY154_04395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY154_04425	COG3932	Exopolysaccharide synthesis, ExoD
FY154_04430	COG1238	metal cluster binding
FY154_04505	COG1612	heme a metabolic process
FY154_04515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY154_04520	COG0010	Belongs to the arginase family
FY154_04525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY154_04530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY154_04540	COG1832	CoA-binding protein
FY154_04565	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_04570	COG2124	cytochrome p450
FY154_04575	COG2199	diguanylate cyclase activity
FY154_04580	COG0740	serine-type endopeptidase activity
FY154_04585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY154_04590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY154_04600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY154_04625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY154_04630	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY154_04635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY154_04645	COG0649	NAD binding
FY154_04655	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY154_04660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY154_04670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY154_04675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY154_04685	COG0713	ATP synthesis coupled electron transport
FY154_04700	COG1007	ATP synthesis coupled electron transport
FY154_04705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY154_04705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY154_04720	COG0442	prolyl-tRNA aminoacylation
FY154_04730	COG1136	(ABC) transporter
FY154_04745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY154_04765	COG0784	Response regulator, receiver
FY154_04775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY154_04780	COG0477	Major facilitator Superfamily
FY154_04795	COG0557	exoribonuclease II activity
FY154_04800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY154_04810	COG0758	DNA mediated transformation
FY154_04815	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY154_04825	COG0540	Belongs to the ATCase OTCase family
FY154_04840	COG1960	acyl-CoA dehydrogenase activity
FY154_04845	COG0456	acetyltransferase
FY154_04865	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY154_04870	COG2824	Alkylphosphonate utilization operon protein PhnA
FY154_04875	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY154_04880	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY154_04885	COG0154	amidase activity
FY154_04890	COG0456	acetyltransferase
FY154_04895	COG3811	Belongs to the UPF0386 family
FY154_04910	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY154_04920	COG0456	acetyltransferase
FY154_04940	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY154_04945	COG0439	Biotin carboxylase
FY154_04950	COG0511	ligase activity, forming carbon-carbon bonds
FY154_04955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY154_04965	COG0436	Aminotransferase
FY154_04985	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_04990	COG1530	ribonuclease E activity
FY154_05000	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY154_05020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY154_05025	COG0384	phenazine biosynthesis protein PhzF
FY154_05045	COG0633	Ferredoxin
FY154_05060	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY154_05065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY154_05075	COG3768	UPF0283 membrane protein
FY154_05080	COG3106	COG3106 Predicted ATPase
FY154_05110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY154_05145	COG0537	adenosine 5'-monophosphoramidase activity
FY154_05170	COG0052	Belongs to the universal ribosomal protein uS2 family
FY154_05175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY154_05180	COG0528	UMP kinase activity
FY154_05185	COG0233	cytoplasmic translational termination
FY154_05190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY154_05200	COG0750	zinc metalloprotease
FY154_05205	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY154_05210	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY154_05215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY154_05220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY154_05225	COG3494	Protein of unknown function (DUF1009)
FY154_05230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY154_05235	COG2186	Transcriptional regulator
FY154_05245	COG0765	amino acid transport
FY154_05250	COG0765	amino acid transport
FY154_05260	COG0372	Belongs to the citrate synthase family
FY154_05275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY154_05285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY154_05290	COG0148	phosphopyruvate hydratase activity
FY154_05300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY154_05305	COG0022	dehydrogenase e1 component
FY154_05305	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY154_05310	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY154_05320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY154_05330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY154_05335	COG0697	spore germination
FY154_05350	COG2867	negative regulation of translational initiation
FY154_05355	COG1546	Belongs to the CinA family
FY154_05360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY154_05360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY154_05370	COG3852	Histidine kinase
FY154_05375	COG2204	response regulator
FY154_05380	COG5000	phosphorelay sensor kinase activity
FY154_05385	COG2204	response regulator
FY154_05390	COG0569	domain protein
FY154_05395	COG1923	regulation of RNA biosynthetic process
FY154_05400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY154_05405	COG3956	TIGRFAM MazG family protein
FY154_05415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY154_05415	COG1648	precorrin-2 dehydrogenase activity
FY154_05455	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY154_05455	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY154_05460	COG0509	glycine decarboxylation via glycine cleavage system
FY154_05465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY154_05490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY154_05495	COG0564	pseudouridine synthase activity
FY154_05515	COG0251	oxidation-reduction process
FY154_05520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY154_05530	COG1671	Belongs to the UPF0178 family
FY154_05545	COG0450	alkyl hydroperoxide reductase
FY154_05555	COG0625	glutathione transferase activity
FY154_05565	COG2801	Transposase and inactivated derivatives
FY154_05570	COG0431	NADPH-dependent FMN reductase
FY154_05580	COG0798	PFAM Bile acid sodium symporter
FY154_05585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY154_05600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY154_05600	COG0321	lipoyl(octanoyl) transferase activity
FY154_05605	COG0084	hydrolase, TatD family'
FY154_05610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY154_05620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY154_05670	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY154_05675	COG2095	MarC family integral membrane protein
FY154_05680	COG0617	tRNA 3'-terminal CCA addition
FY154_05680	COG0517	IMP dehydrogenase activity
FY154_05680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY154_05690	COG0629	single-stranded DNA binding
FY154_05695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY154_05705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY154_05725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY154_05730	COG1121	(ABC) transporter
FY154_05750	COG0667	Aldo Keto reductase
FY154_05760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY154_05845	COG2239	Acts as a magnesium transporter
FY154_05850	COG0243	molybdopterin cofactor binding
FY154_05860	COG0242	peptide deformylase activity
FY154_05870	COG2202	Pas domain
FY154_05870	COG2205	protein histidine kinase activity
FY154_05880	COG0321	lipoyl(octanoyl) transferase activity
FY154_05885	COG1064	alcohol dehydrogenase
FY154_05915	COG1862	Preprotein translocase
FY154_05935	COG2124	cytochrome p450
FY154_05950	COG0596	Alpha beta hydrolase
FY154_05960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY154_05965	COG0626	cystathionine gamma-synthase activity
FY154_05970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_05975	COG4597	amino acid ABC transporter
FY154_05980	COG0765	amino acid transport
FY154_05985	COG1126	abc transporter atp-binding protein
FY154_06230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY154_06245	COG0436	Aminotransferase
FY154_06275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY154_06285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY154_06290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY154_06295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY154_06310	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY154_06315	COG1489	DNA binding
FY154_06320	COG0024	Methionine aminopeptidase
FY154_06325	COG2003	Belongs to the UPF0758 family
FY154_06340	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY154_06365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY154_06370	COG0546	phosphoglycolate phosphatase activity
FY154_06380	COG0114	fumarate hydratase activity
FY154_06390	COG0504	CTP synthase activity
FY154_06400	COG0149	triose-phosphate isomerase activity
FY154_06410	COG0187	DNA topoisomerase II activity
FY154_06420	COG0740	serine-type endopeptidase activity
FY154_06430	COG0640	Transcriptional regulator
FY154_06435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY154_06440	COG0745	RESPONSE REGULATOR receiver
FY154_06460	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY154_06460	COG3264	Mechanosensitive ion channel
FY154_06525	COG1127	ABC transporter
FY154_06530	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY154_06535	COG4948	Mandelate Racemase Muconate Lactonizing
FY154_06545	COG0281	malic enzyme
FY154_06545	COG0280	phosphate acetyltransferase
FY154_06555	COG0778	Nitroreductase
FY154_06560	COG0823	Involved in the tonB-independent uptake of proteins
FY154_06575	COG1368	sulfuric ester hydrolase activity
FY154_06595	COG3265	gluconokinase activity
FY154_06600	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY154_06625	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY154_06645	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY154_06660	COG0318	PFAM AMP-dependent synthetase and ligase
FY154_06670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY154_06670	COG0512	Glutamine amidotransferase of anthranilate synthase
FY154_06675	COG0343	queuine tRNA-ribosyltransferase activity
FY154_06680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY154_06695	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY154_06710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY154_06715	COG0134	indole-3-glycerol-phosphate synthase activity
FY154_06720	COG0315	cyclic pyranopterin monophosphate synthase activity
FY154_06725	COG0303	'Molybdopterin
FY154_06730	COG3706	GGDEF domain
FY154_06740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY154_06740	COG0475	glutathione-regulated potassium exporter activity
FY154_06750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY154_06760	COG2814	Major facilitator Superfamily
FY154_06765	COG0746	molybdenum cofactor guanylyltransferase activity
FY154_06770	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY154_06775	COG0739	heme binding
FY154_06780	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY154_06785	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY154_06790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY154_06795	COG0805	protein transport
FY154_06800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY154_06805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY154_06810	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY154_06815	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY154_06820	COG1472	Belongs to the glycosyl hydrolase 3 family
FY154_06830	COG0018	arginyl-trna synthetase
FY154_06835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY154_06860	COG0525	valine-tRNA ligase activity
FY154_06870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY154_06900	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY154_06905	COG1058	Belongs to the CinA family
FY154_06905	COG1546	Belongs to the CinA family
FY154_06910	COG0589	response to stress
FY154_06915	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY154_06925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY154_06935	COG0640	Transcriptional regulator
FY154_06940	COG1914	H( )-stimulated, divalent metal cation uptake system
FY154_06950	COG1132	(ABC) transporter
FY154_06955	COG0628	permease
FY154_06990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY154_07000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY154_07010	COG0302	gtp cyclohydrolase
FY154_07015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY154_07020	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY154_07030	COG0516	GMP reductase activity
FY154_07030	COG0517	IMP dehydrogenase activity
FY154_07060	COG1760	l-serine dehydratase
FY154_07100	COG0583	DNA-binding transcription factor activity
FY154_07115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY154_07115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY154_07125	COG0347	Belongs to the P(II) protein family
FY154_07130	COG0174	glutamine synthetase
FY154_07160	COG0697	spore germination
FY154_07170	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY154_07180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY154_07210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY154_07215	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY154_07220	COG2186	Transcriptional regulator
FY154_07230	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY154_07235	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY154_07240	COG3845	ABC transporter
FY154_07245	COG1183	phosphatidylcholine synthase activity
FY154_07250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY154_07255	COG0679	Auxin Efflux Carrier
FY154_07260	COG0785	Cytochrome C biogenesis protein
FY154_07280	COG1278	Cold shock
FY154_07330	COG0577	efflux transmembrane transporter activity
FY154_07330	COG1136	(ABC) transporter
FY154_07335	COG0577	efflux transmembrane transporter activity
FY154_07335	COG1136	(ABC) transporter
FY154_07360	COG2151	metal-sulfur cluster biosynthetic enzyme
FY154_07365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY154_07370	COG0719	Fe-S assembly protein
FY154_07375	COG0396	ATPase activity
FY154_07380	COG0719	Fe-S assembly protein
FY154_07385	COG1104	cysteine desulfurase activity
FY154_07390	COG2945	thiolester hydrolase activity
FY154_07395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY154_07400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY154_07410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY154_07415	COG2833	Protein of unknown function (DUF455)
FY154_07420	COG0739	heme binding
FY154_07425	COG0513	Belongs to the DEAD box helicase family
FY154_07450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY154_07460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY154_07465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY154_07470	COG0047	phosphoribosylformylglycinamidine synthase activity
FY154_07485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY154_07490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY154_07515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY154_07520	COG2814	Major facilitator Superfamily
FY154_07525	COG0483	inositol monophosphate 1-phosphatase activity
FY154_07530	COG0483	inositol monophosphate 1-phosphatase activity
FY154_07535	COG0037	tRNA processing
FY154_07540	COG2066	Belongs to the glutaminase family
FY154_07545	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY154_07550	COG0861	Integral membrane protein TerC family
FY154_07565	COG1280	lysine exporter protein (LysE YggA)
FY154_07575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY154_07580	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY154_07590	COG0538	isocitrate dehydrogenase activity
FY154_07600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY154_07605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY154_07610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_07615	COG2313	pseudouridylate synthase activity
FY154_07625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_07630	COG4215	(ABC) transporter
FY154_07640	COG5425	PFAM Usg family protein
FY154_07650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY154_07655	COG1522	sequence-specific DNA binding
FY154_07660	COG1573	uracil-dna glycosylase
FY154_07670	COG2205	protein histidine kinase activity
FY154_07670	COG2202	Pas domain
FY154_07675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY154_07680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY154_07685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY154_07700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY154_07705	COG0842	Transport permease protein
FY154_07710	COG1131	(ABC) transporter
FY154_07715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY154_07715	COG0730	response to heat
FY154_07735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY154_07740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY154_07760	COG0129	dihydroxy-acid dehydratase activity
FY154_07765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY154_07770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY154_07780	COG3739	integral membrane protein
FY154_07785	COG0203	ribosomal protein L17
FY154_07790	COG0202	RNA polymerase activity
FY154_07795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY154_07800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY154_07805	COG0563	adenylate kinase activity
FY154_07810	COG0201	protein transport
FY154_07815	COG0200	Binds to the 23S rRNA
FY154_07820	COG1841	ribosomal large subunit assembly
FY154_07825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY154_07830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY154_07835	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY154_07840	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY154_07845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY154_07850	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY154_07855	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY154_07860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY154_07865	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY154_07870	COG0255	Belongs to the universal ribosomal protein uL29 family
FY154_07875	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY154_07880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY154_07885	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY154_07890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY154_07895	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY154_07900	COG0089	rRNA binding
FY154_07905	COG0088	Forms part of the polypeptide exit tunnel
FY154_07910	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY154_07915	COG0051	transcription antitermination factor activity, RNA binding
FY154_07920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY154_07925	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY154_07930	COG0049	tRNA binding
FY154_07935	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY154_07955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY154_07960	COG0085	RNA polymerase activity
FY154_07965	COG0222	ribosome binding
FY154_07970	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY154_07975	COG0081	regulation of translation
FY154_07980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY154_07990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY154_08000	COG1086	Polysaccharide biosynthesis protein
FY154_08005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY154_08010	COG0861	Integral membrane protein TerC family
FY154_08015	COG3895	Periplasmic Protein
FY154_08035	COG1132	(ABC) transporter
FY154_08040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY154_08060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY154_08095	COG2198	Histidine kinase
FY154_08095	COG0784	Response regulator, receiver
FY154_08095	COG2205	protein histidine kinase activity
FY154_08095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_08100	COG0784	Response regulator, receiver
FY154_08105	COG2202	Pas domain
FY154_08105	COG3920	Histidine kinase
FY154_08110	COG0784	Response regulator, receiver
FY154_08115	COG4251	negative regulation of phosphorylation
FY154_08130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY154_08135	COG1607	acyl-coa hydrolase
FY154_08155	COG2910	NAD(P)H-binding
FY154_08160	COG1733	regulation of RNA biosynthetic process
FY154_08175	COG0556	nucleotide-excision repair
FY154_08185	COG2382	esterase
FY154_08205	COG0484	heat shock protein binding
FY154_08225	COG3706	GGDEF domain
FY154_08245	COG1840	ABC-type Fe3 transport system, periplasmic component
FY154_08250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY154_08265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY154_08275	COG2207	Transcriptional regulator
FY154_08280	COG1064	alcohol dehydrogenase
FY154_08285	COG1252	NADH dehydrogenase
FY154_08290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY154_08295	COG2197	response regulator
FY154_08300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY154_08335	COG0656	L-ascorbic acid biosynthetic process
FY154_08350	COG0440	acetolactate synthase activity
FY154_08355	COG0028	Belongs to the TPP enzyme family
FY154_08365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY154_08370	COG0560	Phosphoserine phosphatase
FY154_08370	COG3830	Belongs to the UPF0237 family
FY154_08390	COG0330	HflC and HflK could
FY154_08395	COG0330	HflC and HflK could
FY154_08405	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY154_08440	COG0277	FAD linked oxidase domain protein
FY154_08445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY154_08485	COG1335	isochorismatase
FY154_08510	COG2264	protein methyltransferase activity
FY154_08515	COG1999	signal sequence binding
FY154_08525	COG0835	chemotaxis
FY154_08535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY154_08540	COG0583	DNA-binding transcription factor activity
FY154_08550	COG1247	-acetyltransferase
FY154_08560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY154_08565	COG0497	DNA recombination
FY154_08570	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY154_08580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY154_08585	COG0849	cell division
FY154_08590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY154_08595	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY154_08600	COG0477	Major facilitator Superfamily
FY154_08605	COG5001	Diguanylate cyclase
FY154_08610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY154_08615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY154_08620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY154_08630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY154_08635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY154_08645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY154_08660	COG0275	rRNA processing
FY154_08665	COG2001	Belongs to the MraZ family
FY154_08670	COG3766	membrane
FY154_08680	COG0754	glutathionylspermidine amidase activity
FY154_08705	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY154_08735	COG4106	trans-aconitate 2-methyltransferase activity
FY154_08755	COG2226	methyltransferase
FY154_08765	COG2267	carboxylic ester hydrolase activity
FY154_08770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY154_08800	COG1376	ErfK ybiS ycfS ynhG family protein
FY154_08805	COG2814	Major facilitator Superfamily
FY154_08835	COG1012	belongs to the aldehyde dehydrogenase family
FY154_08840	COG0174	glutamine synthetase
FY154_08845	COG0531	amino acid
FY154_08855	COG1737	Transcriptional regulator
FY154_08860	COG2182	Extracellular solute-binding protein
FY154_08875	COG3842	ATPase activity
FY154_08935	COG2968	Membrane
FY154_08945	COG0432	Pfam Uncharacterised protein family UPF0047
FY154_08960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY154_08965	COG0358	DNA primase activity
FY154_08990	COG0505	Belongs to the CarA family
FY154_08995	COG0534	Mate efflux family protein
FY154_09010	COG2321	neutral zinc metallopeptidase
FY154_09025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY154_09035	COG3706	GGDEF domain
FY154_09050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY154_09060	COG1522	sequence-specific DNA binding
FY154_09065	COG0492	ferredoxin-NADP+ reductase activity
FY154_09070	COG0583	DNA-binding transcription factor activity
FY154_09080	COG1902	pentaerythritol trinitrate reductase activity
FY154_09105	COG0387	Pfam Sodium calcium exchanger
FY154_09110	COG0436	Aminotransferase
FY154_09115	COG2199	diguanylate cyclase activity
FY154_09115	COG2200	EAL domain
FY154_09130	COG1278	Cold shock
FY154_09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY154_09145	COG1846	Transcriptional regulator
FY154_09150	COG0745	RESPONSE REGULATOR receiver
FY154_09160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY154_09180	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY154_09190	COG1496	oxidoreductase activity
FY154_09205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY154_09215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY154_09230	COG0840	transmembrane signaling receptor activity
FY154_09235	COG1012	belongs to the aldehyde dehydrogenase family
FY154_09240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY154_09245	COG5001	Diguanylate cyclase
FY154_09245	COG3300	MHYT domain
FY154_09250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY154_09255	COG5001	Diguanylate cyclase
FY154_09265	COG0193	aminoacyl-tRNA hydrolase activity
FY154_09275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY154_09300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY154_09310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY154_09310	COG2857	Cytochrome c1
FY154_09330	COG1132	(ABC) transporter
FY154_09335	COG1132	(ABC) transporter
FY154_09340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY154_09345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY154_09360	COG0408	coproporphyrinogen oxidase activity
FY154_09375	COG0617	tRNA 3'-terminal CCA addition
FY154_09390	COG0714	Associated with various cellular activities
FY154_09410	COG0454	-acetyltransferase
FY154_09425	COG0477	Major facilitator Superfamily
FY154_09435	COG0435	Glutathione S-transferase
FY154_09440	COG0494	nUDIX hydrolase
FY154_09455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY154_09460	COG3135	benzoate transporter
FY154_09485	COG0740	serine-type endopeptidase activity
FY154_09500	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY154_09505	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY154_09530	COG4175	Glycine betaine
FY154_09550	COG1435	thymidine kinase activity
FY154_09575	COG1629	transport
FY154_09575	COG4771	TonB-dependent receptor
FY154_09585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY154_09585	COG0512	Glutamine amidotransferase of anthranilate synthase
FY154_09600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY154_09610	COG0366	Alpha amylase catalytic
FY154_09615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_09635	COG1160	GTP binding
FY154_09655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY154_09665	COG0024	Methionine aminopeptidase
FY154_09675	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_09695	COG0583	DNA-binding transcription factor activity
FY154_09710	COG0402	S-adenosylhomocysteine deaminase activity
FY154_09720	COG1304	FMN binding
FY154_09730	COG1309	transcriptional regulator
FY154_09735	COG1686	Belongs to the peptidase S11 family
FY154_09745	COG2351	hydroxyisourate hydrolase activity
FY154_09750	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY154_09775	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY154_09785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY154_09785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_09795	COG0513	Belongs to the DEAD box helicase family
FY154_09805	COG2259	Doxx family
FY154_09810	COG1376	ErfK ybiS ycfS ynhG family protein
FY154_09820	COG2308	Evidence 4 Homologs of previously reported genes of
FY154_09830	COG1305	Transglutaminase-like
FY154_09855	COG4214	carbohydrate transport
FY154_09865	COG4213	ABC transporter substrate-binding protein
FY154_09900	COG0840	transmembrane signaling receptor activity
FY154_09915	COG0646	methionine synthase
FY154_09915	COG1410	methionine synthase
FY154_09960	COG1215	transferase activity, transferring glycosyl groups
FY154_09990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY154_09995	COG2346	COG2346, Truncated hemoglobins
FY154_10015	COG1309	transcriptional regulator
FY154_10030	COG0494	nUDIX hydrolase
FY154_10040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_10045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_10075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY154_10080	COG0830	nickel cation binding
FY154_10085	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY154_10100	COG0804	urea catabolic process
FY154_10105	COG1442	glycosyl transferase family 8
FY154_10110	COG3755	Protein conserved in bacteria
FY154_10120	COG0832	Belongs to the urease beta subunit family
FY154_10125	COG3813	Protein conserved in bacteria
FY154_10130	COG0831	urea catabolic process
FY154_10135	COG0829	nickel cation binding
FY154_10155	COG0411	ABC transporter
FY154_10165	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY154_10180	COG0174	glutamine synthetase
FY154_10185	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_10190	COG2198	Histidine kinase
FY154_10190	COG5002	protein histidine kinase activity
FY154_10190	COG0784	Response regulator, receiver
FY154_10205	COG0726	polysaccharide deacetylase
FY154_10240	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY154_10315	COG0564	pseudouridine synthase activity
FY154_10325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY154_10335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY154_10360	COG0346	lactoylglutathione lyase activity
FY154_10370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY154_10380	COG2832	Protein of unknown function (DUF454)
FY154_10385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY154_10390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_10395	COG4558	Periplasmic binding protein
FY154_10405	COG3721	Heme iron utilization protein
FY154_10420	COG3655	Transcriptional regulator
FY154_10435	COG3657	addiction module killer protein
FY154_10445	COG2205	protein histidine kinase activity
FY154_10485	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_10490	COG4605	iron ion homeostasis
FY154_10495	COG4604	ABC transporter, ATP-binding protein
FY154_10500	COG0783	Belongs to the Dps family
FY154_10515	COG2972	Histidine kinase
FY154_10515	COG0840	transmembrane signaling receptor activity
FY154_10520	COG0656	L-ascorbic acid biosynthetic process
FY154_10525	COG2814	Major facilitator Superfamily
FY154_10535	COG0583	DNA-binding transcription factor activity
FY154_10540	COG0657	acetylesterase activity
FY154_10545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_10565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY154_10570	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY154_10575	COG0288	reversible hydration of carbon dioxide
FY154_10585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY154_10605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY154_10610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY154_10615	COG0778	Nitroreductase
FY154_10620	COG2267	carboxylic ester hydrolase activity
FY154_10625	COG0251	oxidation-reduction process
FY154_10630	COG1335	isochorismatase
FY154_10635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_10645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_10660	COG1175	transmembrane transport
FY154_10665	COG0395	ABC-type sugar transport system, permease component
FY154_10670	COG3842	ATPase activity
FY154_10675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_10685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY154_10700	COG4608	Belongs to the ABC transporter superfamily
FY154_10705	COG0444	Belongs to the ABC transporter superfamily
FY154_10710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_10715	COG0601	transmembrane transport
FY154_10770	COG2159	amidohydrolase
FY154_10775	COG1960	acyl-CoA dehydrogenase activity
FY154_10805	COG0745	RESPONSE REGULATOR receiver
FY154_10815	COG1902	pentaerythritol trinitrate reductase activity
FY154_10815	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY154_10820	COG3842	ATPase activity
FY154_10830	COG1840	ABC-type Fe3 transport system, periplasmic component
FY154_10835	COG1840	ABC-type Fe3 transport system, periplasmic component
FY154_10840	COG0745	RESPONSE REGULATOR receiver
FY154_10850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY154_10855	COG0583	DNA-binding transcription factor activity
FY154_10860	COG1278	Cold shock
FY154_10870	COG4221	oxidoreductase activity
FY154_10875	COG0625	glutathione transferase activity
FY154_10895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY154_10900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY154_10915	COG3077	Addiction module antitoxin, RelB DinJ family
FY154_10950	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_10960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_10965	COG4597	amino acid ABC transporter
FY154_10970	COG0765	amino acid transport
FY154_10995	COG0747	negative chemotaxis
FY154_11000	COG0601	transmembrane transport
FY154_11005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_11010	COG0444	Belongs to the ABC transporter superfamily
FY154_11035	COG4213	ABC transporter substrate-binding protein
FY154_11040	COG1129	ABC transporter
FY154_11045	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_11060	COG0667	Aldo Keto reductase
FY154_11085	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_11090	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_11095	COG1129	ABC transporter
FY154_11115	COG3920	Histidine kinase
FY154_11140	COG0753	catalase activity
FY154_11160	COG1278	Cold shock
FY154_11175	COG0604	alcohol dehydrogenase
FY154_11185	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_11190	COG1902	pentaerythritol trinitrate reductase activity
FY154_11195	COG4221	oxidoreductase activity
FY154_11200	COG1309	transcriptional regulator
FY154_11215	COG1280	lysine exporter protein (LysE YggA)
FY154_11225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY154_11270	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY154_11275	COG1309	transcriptional regulator
FY154_11280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_11285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY154_11295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY154_11300	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY154_11320	COG0583	DNA-binding transcription factor activity
FY154_11325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_11330	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY154_11335	COG4149	molybdate abc transporter
FY154_11340	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY154_11355	COG2022	thiamine diphosphate biosynthetic process
FY154_11370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY154_11380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY154_11390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY154_11410	COG1132	(ABC) transporter
FY154_11415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY154_11460	COG4166	transmembrane transport
FY154_11465	COG0601	transmembrane transport
FY154_11470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_11485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY154_11490	COG3142	Participates in the control of copper homeostasis
FY154_11495	COG2814	Major facilitator Superfamily
FY154_11510	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_11515	COG1737	Transcriptional regulator
FY154_11525	COG3842	ATPase activity
FY154_11535	COG0395	ABC-type sugar transport system, permease component
FY154_11555	COG2188	Transcriptional regulator
FY154_11560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY154_11565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY154_11570	COG1940	carbohydrate kinase activity
FY154_11580	COG0671	phosphoesterase, PA-phosphatase related
FY154_11585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY154_11590	COG0156	8-amino-7-oxononanoate synthase activity
FY154_11600	COG0729	surface antigen
FY154_11610	COG0835	chemotaxis
FY154_11620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY154_11625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY154_11630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY154_11635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY154_11640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY154_11645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY154_11660	COG4974	Belongs to the 'phage' integrase family
FY154_11685	COG1280	lysine exporter protein (LysE YggA)
FY154_11695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY154_11700	COG0567	Dehydrogenase, E1 component
FY154_11705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY154_11710	COG0045	succinate-CoA ligase (ADP-forming) activity
FY154_11715	COG0039	L-malate dehydrogenase activity
FY154_11720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY154_11755	COG2264	protein methyltransferase activity
FY154_11770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY154_11775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY154_11780	COG0181	hydroxymethylbilane synthase activity
FY154_11820	COG1872	DUF167
FY154_11825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY154_11835	COG1217	gtp-binding protein TYPA
FY154_11840	COG0339	signal peptide processing
FY154_11845	COG1846	Transcriptional regulator
FY154_11855	COG0137	argininosuccinate synthase activity
FY154_11865	COG1280	lysine exporter protein (LysE YggA)
FY154_11870	COG1122	ATPase activity
FY154_11875	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY154_11885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY154_11900	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY154_11905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY154_11910	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY154_11920	COG4181	ATPase activity
FY154_11930	COG0670	Belongs to the BI1 family
FY154_11945	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY154_11950	COG4133	protoheme IX ABC transporter activity
FY154_11955	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY154_11960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY154_11985	COG2917	probably involved in intracellular septation
FY154_11990	COG0552	protein localization to endoplasmic reticulum
FY154_11995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY154_12000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY154_12015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY154_12020	COG1605	Chorismate mutase
FY154_12020	COG0287	Prephenate dehydrogenase
FY154_12025	COG0228	four-way junction DNA binding
FY154_12030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY154_12035	COG0336	Belongs to the RNA methyltransferase TrmD family
FY154_12045	COG0335	large ribosomal subunit rRNA binding
FY154_12050	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY154_12055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_12070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY154_12090	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY154_12110	COG0488	(ABC) transporter
FY154_12120	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY154_12130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY154_12135	COG0142	geranyltranstransferase activity
FY154_12140	COG2885	chlorophyll binding
FY154_12145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY154_12150	COG2223	nitrite transmembrane transporter activity
FY154_12155	COG1349	DNA-binding transcription factor activity
FY154_12160	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY154_12165	COG2197	response regulator
FY154_12170	COG1132	(ABC) transporter
FY154_12180	COG3459	Glycosyltransferase 36 associated
FY154_12185	COG1473	amidohydrolase
FY154_12190	COG0579	oxidoreductase
FY154_12200	COG0129	dihydroxy-acid dehydratase activity
FY154_12205	COG2084	Dehydrogenase
FY154_12210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY154_12215	COG0277	FAD linked oxidase domain protein
FY154_12220	COG2186	Transcriptional regulator
FY154_12230	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY154_12235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY154_12240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY154_12245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY154_12255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY154_12260	COG0495	leucyl-tRNA aminoacylation
FY154_12275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY154_12280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY154_12295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY154_12300	COG1946	Acyl-CoA thioesterase
FY154_12305	COG0347	Belongs to the P(II) protein family
FY154_12310	COG0004	ammonium transporteR
FY154_12315	COG1674	ftsk spoiiie
FY154_12320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY154_12335	COG0745	RESPONSE REGULATOR receiver
FY154_12345	COG1329	Transcriptional regulator
FY154_12350	COG2902	Dehydrogenase
FY154_12355	COG2270	Major facilitator Superfamily
FY154_12370	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_12385	COG0494	nUDIX hydrolase
FY154_12390	COG2861	carbohydrate metabolic process
FY154_12395	COG0793	Belongs to the peptidase S41A family
FY154_12405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY154_12410	COG0799	negative regulation of ribosome biogenesis
FY154_12415	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY154_12420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY154_12425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY154_12430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY154_12445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY154_12450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY154_12475	COG0066	3-isopropylmalate dehydratase activity
FY154_12480	COG0473	3-isopropylmalate dehydrogenase activity
FY154_12485	COG1858	cytochrome C peroxidase
FY154_12490	COG1797	cobyrinic acid a,c-diamide synthase activity
FY154_12500	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY154_12565	COG1492	cobalamin metabolic process
FY154_12580	COG4948	Mandelate Racemase Muconate Lactonizing
FY154_12585	COG3254	rhamnose metabolic process
FY154_12595	COG1063	alcohol dehydrogenase
FY154_12620	COG1129	ABC transporter
FY154_12625	COG2186	Transcriptional regulator
FY154_12630	COG2721	sulfolactate sulfo-lyase activity
FY154_12635	COG0138	bifunctional purine biosynthesis protein purh
FY154_12645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY154_12645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY154_12650	COG0501	Belongs to the peptidase M48B family
FY154_12670	COG0357	Ribosomal RNA small subunit methyltransferase G
FY154_12675	COG0445	tRNA wobble uridine modification
FY154_12680	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY154_12685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY154_12690	COG1981	membrane
FY154_12695	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY154_12700	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY154_12705	COG0424	maF-like protein
FY154_12710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY154_12715	COG0237	dephospho-CoA kinase activity
FY154_12725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY154_12730	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY154_12740	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY154_12765	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY154_12780	COG0135	phosphoribosylanthranilate isomerase activity
FY154_12785	COG0133	tryptophan synthase activity
FY154_12790	COG0159	tryptophan synthase activity
FY154_12795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY154_12810	COG1074	ATP-dependent DNA helicase activity
FY154_12820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY154_12825	COG0802	atpase or kinase
FY154_12830	COG2205	protein histidine kinase activity
FY154_12835	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY154_12840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY154_12845	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY154_12845	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY154_12850	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY154_12855	COG0642	Histidine kinase
FY154_12860	COG0745	RESPONSE REGULATOR receiver
FY154_12865	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY154_12875	COG1652	LysM domain
FY154_12880	COG1072	(Pantothenic acid kinase))
FY154_12885	COG0140	phosphoribosyl-ATP diphosphatase activity
FY154_12890	COG0107	imidazoleglycerol-phosphate synthase activity
FY154_12895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY154_12900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY154_12910	COG0131	Imidazoleglycerol-phosphate dehydratase
FY154_12915	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY154_12920	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY154_12930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY154_12945	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY154_12955	COG1643	Atp-dependent helicase
FY154_13015	COG1072	(Pantothenic acid kinase))
FY154_13025	COG1780	Probably involved in ribonucleotide reductase function
FY154_13045	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY154_13075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_13085	COG2813	Specifically methylates the guanine in position
FY154_13090	COG1185	polyribonucleotide nucleotidyltransferase activity
FY154_13095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY154_13100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY154_13105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY154_13110	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY154_13110	COG3064	Membrane
FY154_13125	COG0779	Required for maturation of 30S ribosomal subunits
FY154_13130	COG2814	Major facilitator Superfamily
FY154_13140	COG2951	lytic endotransglycosylase activity
FY154_13145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY154_13155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY154_13160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY154_13175	COG2816	NAD+ diphosphatase activity
FY154_13180	COG0077	Prephenate dehydratase
FY154_13180	COG1605	Chorismate mutase
FY154_13185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY154_13190	COG3474	cytochrome
FY154_13200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY154_13205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY154_13210	COG1278	Cold shock
FY154_13215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY154_13225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY154_13225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY154_13235	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY154_13265	COG2900	Belongs to the SlyX family
FY154_13275	COG0484	heat shock protein binding
FY154_13280	COG0443	Heat shock 70 kDa protein
FY154_13295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY154_13300	COG1744	ABC transporter substrate-binding protein PnrA-like
FY154_13305	COG3845	ABC transporter
FY154_13310	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY154_13315	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY154_13320	COG0295	cytidine deaminase activity
FY154_13330	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY154_13335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY154_13345	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY154_13350	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY154_13355	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY154_13365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY154_13370	COG1845	cytochrome c oxidase, subunit III
FY154_13375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY154_13380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY154_13385	COG0477	Major facilitator Superfamily
FY154_13390	COG0070	glutamate synthase
FY154_13390	COG0069	glutamate synthase activity
FY154_13390	COG0067	glutamate synthase
FY154_13395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY154_13410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY154_13420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY154_13450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_13470	COG0848	biopolymer transport protein
FY154_13480	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY154_13495	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY154_13500	COG3454	Phosphonate metabolism
FY154_13505	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY154_13510	COG3639	organic phosphonate transmembrane transporter activity
FY154_13515	COG3639	organic phosphonate transmembrane transporter activity
FY154_13520	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY154_13525	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY154_13535	COG4778	phosphonate C-P lyase system protein PhnL
FY154_13540	COG4107	phosphonate C-P lyase system protein PhnK
FY154_13545	COG3627	carbon phosphorus lyase activity
FY154_13550	COG3626	phosphonate metabolism
FY154_13555	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY154_13560	COG3624	Phosphonate C-P lyase system protein PhnG
FY154_13565	COG2188	Transcriptional regulator
FY154_13570	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY154_13575	COG0837	glucose binding
FY154_13580	COG1803	Methylglyoxal synthase
FY154_13585	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY154_13590	COG4166	transmembrane transport
FY154_13595	COG4174	ABC transporter (Permease)
FY154_13600	COG4239	(ABC) transporter, permease
FY154_13605	COG4172	Belongs to the ABC transporter superfamily
FY154_13610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_13615	COG0174	glutamine synthetase
FY154_13620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_13625	COG3265	gluconokinase activity
FY154_13630	COG1174	glycine betaine transport
FY154_13635	COG1125	glycine betaine transport
FY154_13640	COG1174	glycine betaine transport
FY154_13645	COG1732	Glycine betaine
FY154_13655	COG1959	2 iron, 2 sulfur cluster binding
FY154_13660	COG1840	ABC-type Fe3 transport system, periplasmic component
FY154_13670	COG4269	membrane
FY154_13685	COG0697	spore germination
FY154_13700	COG0791	NLP P60 protein
FY154_13710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY154_13715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY154_13750	COG4964	Belongs to the GSP D family
FY154_13795	COG3422	double-strand break repair
FY154_13800	COG3757	hydrolase, family 25
FY154_13805	COG0697	spore germination
FY154_13810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY154_13825	COG0492	ferredoxin-NADP+ reductase activity
FY154_13840	COG0481	GTPase activity
FY154_13845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY154_13860	COG1396	sequence-specific DNA binding
FY154_13875	COG2169	Transcriptional regulator
FY154_13875	COG1917	Cupin 2, conserved barrel domain protein
FY154_13880	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY154_13905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY154_13910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY154_13915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY154_13925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY154_13930	COG0072	phenylalanine-tRNA ligase activity
FY154_13930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY154_13935	COG0667	Aldo Keto reductase
FY154_13955	COG4977	sequence-specific DNA binding
FY154_13980	COG1570	exodeoxyribonuclease VII activity
FY154_13985	COG4948	Mandelate Racemase Muconate Lactonizing
FY154_13995	COG1846	Transcriptional regulator
FY154_14000	COG0697	spore germination
FY154_14005	COG2309	aminopeptidase activity
FY154_14010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY154_14015	COG1393	Belongs to the ArsC family
FY154_14030	COG1309	transcriptional regulator
FY154_14040	COG0519	Catalyzes the synthesis of GMP from XMP
FY154_14040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY154_14055	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY154_14085	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY154_14095	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY154_14105	COG1968	undecaprenyl-diphosphatase activity
FY154_14120	COG0284	orotidine-5'-phosphate decarboxylase activity
FY154_14130	COG3963	phosphatidate phosphatase activity
FY154_14140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY154_14145	COG0792	nuclease activity
FY154_14160	COG1175	transmembrane transport
FY154_14165	COG0395	ABC-type sugar transport system, permease component
FY154_14170	COG3842	ATPase activity
FY154_14180	COG0189	ligase activity
FY154_14190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY154_14195	COG1280	lysine exporter protein (LysE YggA)
FY154_14200	COG0756	dUTP diphosphatase activity
FY154_14205	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY154_14210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY154_14225	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY154_14230	COG2226	methyltransferase
FY154_14235	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY154_14240	COG1024	Enoyl-CoA hydratase
FY154_14245	COG0268	Binds directly to 16S ribosomal RNA
FY154_14275	COG1278	Cold shock
FY154_14310	COG0411	ABC transporter
FY154_14315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY154_14320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY154_14325	COG1454	alcohol dehydrogenase
FY154_14330	COG0747	negative chemotaxis
FY154_14335	COG0601	transmembrane transport
FY154_14345	COG4608	Belongs to the ABC transporter superfamily
FY154_14350	COG1349	DNA-binding transcription factor activity
FY154_14355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY154_14380	COG4302	ethanolamine ammonia-lyase activity
FY154_14385	COG0025	NhaP-type Na H and K H
FY154_14390	COG4106	trans-aconitate 2-methyltransferase activity
FY154_14405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_14410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_14415	COG0601	transmembrane transport
FY154_14440	COG4172	Belongs to the ABC transporter superfamily
FY154_14445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY154_14475	COG0596	Alpha beta hydrolase
FY154_14490	COG1764	response to oxidative stress
FY154_14500	COG0596	Alpha beta hydrolase
FY154_14515	COG0783	Belongs to the Dps family
FY154_14520	COG0243	molybdopterin cofactor binding
FY154_14530	COG4566	intracellular signal transduction
FY154_14535	COG4566	intracellular signal transduction
FY154_14545	COG2140	Oxalate decarboxylase
FY154_14565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY154_14575	COG1414	Transcriptional regulator
FY154_14590	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_14610	COG1522	sequence-specific DNA binding
FY154_14635	COG0628	permease
FY154_14645	COG2235	arginine
FY154_14680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY154_14690	COG0702	epimerase
FY154_14695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY154_14700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_14705	COG0745	RESPONSE REGULATOR receiver
FY154_14710	COG5002	protein histidine kinase activity
FY154_14725	COG2233	PERMEase
FY154_14785	COG0395	ABC-type sugar transport system, permease component
FY154_14790	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY154_14800	COG3842	ATPase activity
FY154_14835	COG1653	transport
FY154_14845	COG0395	ABC-type sugar transport system, permease component
FY154_14850	COG3842	ATPase activity
FY154_14865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY154_14870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_14875	COG1116	anion transmembrane transporter activity
FY154_14880	COG0395	ABC-type sugar transport system, permease component
FY154_14885	COG1175	transmembrane transport
FY154_14915	COG1609	Transcriptional regulator
FY154_14930	COG1082	Xylose isomerase domain protein TIM barrel
FY154_14945	COG3842	ATPase activity
FY154_14950	COG0395	ABC-type sugar transport system, permease component
FY154_14955	COG1175	transmembrane transport
FY154_14960	COG1653	transport
FY154_14965	COG1309	transcriptional regulator
FY154_14970	COG0673	inositol 2-dehydrogenase activity
FY154_14985	COG0673	inositol 2-dehydrogenase activity
FY154_14990	COG1278	Cold shock
FY154_15000	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY154_15020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY154_15025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY154_15040	COG3842	ATPase activity
FY154_15045	COG0395	ABC-type sugar transport system, permease component
FY154_15050	COG1175	transmembrane transport
FY154_15060	COG3618	amidohydrolase
FY154_15065	COG4948	Mandelate Racemase Muconate Lactonizing
FY154_15070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_15075	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_15080	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY154_15085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY154_15090	COG2186	Transcriptional regulator
FY154_15105	COG0667	Aldo Keto reductase
FY154_15135	COG4977	sequence-specific DNA binding
FY154_15140	COG2223	nitrite transmembrane transporter activity
FY154_15145	COG1609	Transcriptional regulator
FY154_15150	COG1063	alcohol dehydrogenase
FY154_15155	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_15165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_15170	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY154_15175	COG1175	transmembrane transport
FY154_15180	COG0395	ABC-type sugar transport system, permease component
FY154_15195	COG0395	ABC-type sugar transport system, permease component
FY154_15205	COG2182	Extracellular solute-binding protein
FY154_15210	COG0626	cystathionine gamma-synthase activity
FY154_15225	COG0454	-acetyltransferase
FY154_15230	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY154_15240	COG1121	(ABC) transporter
FY154_15245	COG0523	cobalamin synthesis protein
FY154_15260	COG0523	cobalamin synthesis protein
FY154_15265	COG1653	transport
FY154_15270	COG1175	transmembrane transport
FY154_15275	COG0395	ABC-type sugar transport system, permease component
FY154_15280	COG3842	ATPase activity
FY154_15290	COG3047	cAMP biosynthetic process
FY154_15315	COG0583	DNA-binding transcription factor activity
FY154_15320	COG1879	ABC-type sugar transport system periplasmic component
FY154_15325	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_15330	COG1129	ABC transporter
FY154_15340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY154_15345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_15355	COG3257	ureidoglycine aminohydrolase activity
FY154_15365	COG5001	Diguanylate cyclase
FY154_15370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY154_15380	COG0747	negative chemotaxis
FY154_15385	COG0601	transmembrane transport
FY154_15390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_15400	COG4608	Belongs to the ABC transporter superfamily
FY154_15405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY154_15420	COG0346	lactoylglutathione lyase activity
FY154_15430	COG0129	dihydroxy-acid dehydratase activity
FY154_15435	COG1879	ABC-type sugar transport system periplasmic component
FY154_15440	COG1129	ABC transporter
FY154_15445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_15450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_15455	COG2186	Transcriptional regulator
FY154_15470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY154_15475	COG0587	DNA-directed DNA polymerase activity
FY154_15505	COG0673	inositol 2-dehydrogenase activity
FY154_15515	COG3842	ATPase activity
FY154_15520	COG0395	ABC-type sugar transport system, permease component
FY154_15525	COG1175	transmembrane transport
FY154_15530	COG1653	transport
FY154_15540	COG0673	inositol 2-dehydrogenase activity
FY154_15555	COG5001	Diguanylate cyclase
FY154_15570	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY154_15575	COG2894	cell division
FY154_15580	COG0850	regulation of cytokinetic process
FY154_15585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY154_15590	COG2186	Transcriptional regulator
FY154_15595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY154_15605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY154_15610	COG1063	alcohol dehydrogenase
FY154_15615	COG1312	Catalyzes the dehydration of D-mannonate
FY154_15635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY154_15640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY154_15640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY154_15645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_15660	COG0625	glutathione transferase activity
FY154_15665	COG4172	Belongs to the ABC transporter superfamily
FY154_15670	COG1921	L-seryl-tRNASec selenium transferase activity
FY154_15685	COG3964	amidohydrolase
FY154_15695	COG0601	transmembrane transport
FY154_15700	COG0747	negative chemotaxis
FY154_15705	COG0438	transferase activity, transferring glycosyl groups
FY154_15740	COG4989	oxidoreductase activity
FY154_15750	COG2188	Transcriptional regulator
FY154_15755	COG3842	ATPase activity
FY154_15760	COG1653	transport
FY154_15765	COG1175	transmembrane transport
FY154_15770	COG0395	ABC-type sugar transport system, permease component
FY154_15775	COG1501	Belongs to the glycosyl hydrolase 31 family
FY154_15785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_15790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY154_15795	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY154_15800	COG0352	thiamine-phosphate diphosphorylase activity
FY154_15805	COG0351	phosphomethylpyrimidine kinase
FY154_15810	COG1522	sequence-specific DNA binding
FY154_15815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY154_15820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_15835	COG2204	response regulator
FY154_15840	COG4191	Histidine kinase
FY154_15845	COG1301	dicarboxylic acid transport
FY154_15850	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY154_15855	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_15865	COG1473	amidohydrolase
FY154_15885	COG1215	transferase activity, transferring glycosyl groups
FY154_15895	COG2942	2-epimerase
FY154_15920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY154_15930	COG2197	response regulator
FY154_15960	COG3307	-O-antigen
FY154_15965	COG1596	polysaccharide export
FY154_15970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY154_15980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY154_15985	COG2972	Histidine kinase
FY154_15985	COG0840	transmembrane signaling receptor activity
FY154_15990	COG1376	ErfK ybiS ycfS ynhG family protein
FY154_16000	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_16010	COG2094	Belongs to the DNA glycosylase MPG family
FY154_16025	COG1609	Transcriptional regulator
FY154_16030	COG1653	transport
FY154_16045	COG3842	ATPase activity
FY154_16055	COG0673	inositol 2-dehydrogenase activity
FY154_16060	COG0602	queuosine metabolic process
FY154_16065	COG0720	synthase
FY154_16070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY154_16075	COG0673	inositol 2-dehydrogenase activity
FY154_16090	COG0395	ABC-type sugar transport system, permease component
FY154_16095	COG1175	transmembrane transport
FY154_16120	COG0583	DNA-binding transcription factor activity
FY154_16125	COG0280	phosphate acetyltransferase
FY154_16125	COG0281	malic enzyme
FY154_16140	COG0765	amino acid transport
FY154_16145	COG1126	abc transporter atp-binding protein
FY154_16150	COG2079	MmgE PrpD family protein
FY154_16155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_16180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY154_16190	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY154_16195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY154_16200	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_16205	COG1129	ABC transporter
FY154_16220	COG1473	amidohydrolase
FY154_16225	COG0747	negative chemotaxis
FY154_16240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_16245	COG0601	transmembrane transport
FY154_16250	COG0583	DNA-binding transcription factor activity
FY154_16255	COG1446	asparaginase
FY154_16270	COG0747	negative chemotaxis
FY154_16290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_16295	COG0601	transmembrane transport
FY154_16300	COG2197	response regulator
FY154_16305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY154_16310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY154_16320	COG3842	ATPase activity
FY154_16325	COG0395	ABC-type sugar transport system, permease component
FY154_16330	COG1175	transmembrane transport
FY154_16340	COG0673	inositol 2-dehydrogenase activity
FY154_16345	COG0673	inositol 2-dehydrogenase activity
FY154_16365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_16370	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY154_16390	COG1595	DNA-templated transcription, initiation
FY154_16395	COG1120	ATPase activity
FY154_16400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_16415	COG2226	methyltransferase
FY154_16425	COG1120	ATPase activity
FY154_16430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_16450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY154_16475	COG1012	belongs to the aldehyde dehydrogenase family
FY154_16480	COG0473	3-isopropylmalate dehydrogenase activity
FY154_16485	COG1012	belongs to the aldehyde dehydrogenase family
FY154_16490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_16525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_16530	COG4172	Belongs to the ABC transporter superfamily
FY154_16535	COG1522	sequence-specific DNA binding
FY154_16545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_16560	COG0583	DNA-binding transcription factor activity
FY154_16570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_16575	COG1126	abc transporter atp-binding protein
FY154_16585	COG1473	amidohydrolase
FY154_16590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16600	COG1959	2 iron, 2 sulfur cluster binding
FY154_16610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY154_16615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16645	COG1960	acyl-CoA dehydrogenase activity
FY154_16655	COG0747	negative chemotaxis
FY154_16670	COG0444	Belongs to the ABC transporter superfamily
FY154_16680	COG0667	Aldo Keto reductase
FY154_16690	COG0583	DNA-binding transcription factor activity
FY154_16695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16700	COG4166	transmembrane transport
FY154_16710	COG0747	negative chemotaxis
FY154_16715	COG1473	amidohydrolase
FY154_16720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_16760	COG4608	Belongs to the ABC transporter superfamily
FY154_16765	COG0444	Belongs to the ABC transporter superfamily
FY154_16775	COG0601	transmembrane transport
FY154_16785	COG2186	Transcriptional regulator
FY154_16800	COG0300	oxidoreductase activity
FY154_16810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY154_16810	COG3453	Protein conserved in bacteria
FY154_16815	COG0640	Transcriptional regulator
FY154_16825	COG2391	methyltransferase activity
FY154_16830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY154_16840	COG0022	dehydrogenase e1 component
FY154_16850	COG1960	acyl-CoA dehydrogenase activity
FY154_16855	COG0183	Belongs to the thiolase family
FY154_16865	COG1960	acyl-CoA dehydrogenase activity
FY154_16870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY154_16890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY154_16895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY154_16900	COG4952	isomerase
FY154_16905	COG3347	Dehydrogenase
FY154_16905	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_16910	COG1349	DNA-binding transcription factor activity
FY154_16920	COG1129	ABC transporter
FY154_16925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_16930	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_16935	COG3254	rhamnose metabolic process
FY154_16950	COG2264	protein methyltransferase activity
FY154_16955	COG5001	Diguanylate cyclase
FY154_16970	COG4335	DNA alkylation repair
FY154_16975	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY154_16980	COG4208	sulfate ABC transporter
FY154_16990	COG4150	thiosulfate binding
FY154_16995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY154_17010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY154_17020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY154_17030	COG1040	competence protein
FY154_17035	COG2226	methyltransferase
FY154_17050	COG0494	nUDIX hydrolase
FY154_17060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY154_17065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY154_17070	COG0653	protein targeting
FY154_17075	COG0697	spore germination
FY154_17140	COG2244	polysaccharide biosynthetic process
FY154_17155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY154_17165	COG3206	protein involved in exopolysaccharide biosynthesis
FY154_17165	COG0489	protein tyrosine kinase activity
FY154_17180	COG0438	transferase activity, transferring glycosyl groups
FY154_17185	COG0438	transferase activity, transferring glycosyl groups
FY154_17190	COG0438	transferase activity, transferring glycosyl groups
FY154_17205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY154_17210	COG2273	Hydrolase Family 16
FY154_17210	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY154_17225	COG3842	ATPase activity
FY154_17230	COG3833	ABC-type maltose transport systems, permease component
FY154_17285	COG1396	sequence-specific DNA binding
FY154_17295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY154_17300	COG1129	ABC transporter
FY154_17305	COG4214	carbohydrate transport
FY154_17310	COG4213	ABC transporter substrate-binding protein
FY154_17325	COG0346	lactoylglutathione lyase activity
FY154_17330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY154_17330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY154_17335	COG4770	biotin carboxylase activity
FY154_17350	COG0625	glutathione transferase activity
FY154_17355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY154_17360	COG1396	sequence-specific DNA binding
FY154_17360	COG3800	Transcriptional regulator
FY154_17370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY154_17380	COG0300	oxidoreductase activity
FY154_17390	COG2096	Adenosyltransferase
FY154_17400	COG2086	electron transfer activity
FY154_17410	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY154_17420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY154_17425	COG0165	Argininosuccinate lyase
FY154_17460	COG2884	Cell division ATP-binding protein ftsE
FY154_17480	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY154_17490	COG0287	Prephenate dehydrogenase
FY154_17495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY154_17500	COG2226	methyltransferase
FY154_17505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY154_17525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY154_17530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY154_17570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY154_17575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY154_17585	COG4974	Belongs to the 'phage' integrase family
FY154_17590	COG0825	malonyl-CoA metabolic process
FY154_17595	COG3034	peptidoglycan biosynthetic process
FY154_17600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY154_17600	COG0425	Belongs to the sulfur carrier protein TusA family
FY154_17605	COG0523	cobalamin synthesis protein
FY154_17610	COG1686	Belongs to the peptidase S11 family
FY154_17615	COG1473	amidohydrolase
FY154_17625	COG4953	penicillin-binding protein 1C
FY154_17630	COG2373	Large extracellular alpha-helical protein
FY154_17635	COG2835	tetraacyldisaccharide 4'-kinase activity
FY154_17665	COG0482	sulfurtransferase activity
FY154_17680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY154_17695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY154_17700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY154_17705	COG0037	tRNA processing
FY154_17715	COG2885	chlorophyll binding
FY154_17720	COG0823	Involved in the tonB-independent uptake of proteins
FY154_17740	COG0824	Thioesterase
FY154_17750	COG0494	nUDIX hydrolase
FY154_17765	COG2255	four-way junction helicase activity
FY154_17770	COG0632	four-way junction helicase activity
FY154_17775	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY154_17780	COG0840	transmembrane signaling receptor activity
FY154_17785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_17790	COG0217	transcriptional regulatory protein
FY154_17805	COG1692	metallophosphoesterase
FY154_17815	COG1253	flavin adenine dinucleotide binding
FY154_17855	COG0126	phosphoglycerate kinase activity
FY154_17860	COG3588	fructose-bisphosphate aldolase
FY154_17880	COG0254	rRNA binding
FY154_17885	COG1132	(ABC) transporter
FY154_17905	COG0483	inositol monophosphate 1-phosphatase activity
FY154_17935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY154_17940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY154_17945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY154_17950	COG0457	Tetratricopeptide repeat
FY154_17955	COG3750	Belongs to the UPF0335 family
FY154_17975	COG0469	pyruvate kinase activity
FY154_17980	COG3108	Peptidase M15
FY154_17985	COG2204	response regulator
FY154_17990	COG1164	Oligoendopeptidase f
FY154_17995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY154_18005	COG5310	Homospermidine synthase
FY154_18015	COG0737	Belongs to the 5'-nucleotidase family
FY154_18020	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY154_18025	COG0330	HflC and HflK could
FY154_18055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY154_18060	COG2951	lytic endotransglycosylase activity
FY154_18075	COG2205	protein histidine kinase activity
FY154_18090	COG0070	glutamate synthase
FY154_18090	COG0067	glutamate synthase
FY154_18090	COG0069	glutamate synthase activity
FY154_18105	COG2205	protein histidine kinase activity
FY154_18110	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY154_18115	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY154_18120	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY154_18130	COG0252	asparaginase activity
FY154_18140	COG1027	Aspartate ammonia-lyase
FY154_18145	COG2186	Transcriptional regulator
FY154_18165	COG1309	transcriptional regulator
FY154_18185	COG4176	ABC-type proline glycine betaine transport system permease component
FY154_18190	COG0517	IMP dehydrogenase activity
FY154_18190	COG4175	Glycine betaine
FY154_18195	COG2986	histidine ammonia-lyase
FY154_18200	COG1609	Transcriptional regulator
FY154_18220	COG1082	Xylose isomerase domain protein TIM barrel
FY154_18225	COG0673	inositol 2-dehydrogenase activity
FY154_18230	COG1082	Xylose isomerase domain protein TIM barrel
FY154_18255	COG3550	peptidyl-serine autophosphorylation
FY154_18305	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FY154_18320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY154_18345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_18355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_18360	COG0601	transmembrane transport
FY154_18365	COG0747	negative chemotaxis
FY154_18375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY154_18380	COG1454	alcohol dehydrogenase
FY154_18420	COG2308	Evidence 4 Homologs of previously reported genes of
FY154_18420	COG2307	Protein conserved in bacteria
FY154_18435	COG0488	(ABC) transporter
FY154_18440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY154_18445	COG2186	Transcriptional regulator
FY154_18460	COG1175	transmembrane transport
FY154_18465	COG0395	ABC-type sugar transport system, permease component
FY154_18475	COG3842	ATPase activity
FY154_18500	COG1304	FMN binding
FY154_18515	COG1063	alcohol dehydrogenase
FY154_18520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY154_18525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_18535	COG0765	amino acid transport
FY154_18540	COG0765	amino acid transport
FY154_18545	COG4221	oxidoreductase activity
FY154_18550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY154_18555	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_18560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY154_18575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY154_18590	COG0697	spore germination
FY154_18595	COG0697	spore germination
FY154_18600	COG0511	ligase activity, forming carbon-carbon bonds
FY154_18605	COG0439	Biotin carboxylase
FY154_18615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY154_18620	COG1984	allophanate hydrolase subunit 2
FY154_18625	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY154_18630	COG3842	ATPase activity
FY154_18640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY154_18650	COG0436	Aminotransferase
FY154_18665	COG0840	transmembrane signaling receptor activity
FY154_18665	COG2972	Histidine kinase
FY154_18670	COG1070	Carbohydrate kinase
FY154_18675	COG1830	Aldolase
FY154_18680	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY154_18685	COG0667	Aldo Keto reductase
FY154_18695	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_18700	COG1129	ABC transporter
FY154_18705	COG1879	ABC-type sugar transport system periplasmic component
FY154_18740	COG0071	Belongs to the small heat shock protein (HSP20) family
FY154_18755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY154_18770	COG0395	ABC-type sugar transport system, permease component
FY154_18785	COG3842	ATPase activity
FY154_18800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY154_18800	COG1648	precorrin-2 dehydrogenase activity
FY154_18805	COG0243	molybdopterin cofactor binding
FY154_18815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY154_18820	COG1116	anion transmembrane transporter activity
FY154_18825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_18830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY154_18840	COG3707	response regulator
FY154_18845	COG1802	Transcriptional regulator
FY154_18850	COG1914	H( )-stimulated, divalent metal cation uptake system
FY154_18855	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY154_18860	COG4336	lyase activity
FY154_18865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY154_18870	COG4770	biotin carboxylase activity
FY154_18875	COG0366	Alpha amylase catalytic
FY154_18885	COG4771	TonB-dependent receptor
FY154_18890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY154_18910	COG1414	Transcriptional regulator
FY154_18915	COG1475	DNA binding
FY154_18920	COG1192	Involved in chromosome partitioning
FY154_18950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY154_18960	COG2986	histidine ammonia-lyase
FY154_18965	COG1228	amidohydrolase
FY154_18970	COG0402	S-adenosylhomocysteine deaminase activity
FY154_19010	COG4172	Belongs to the ABC transporter superfamily
FY154_19015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_19020	COG0601	transmembrane transport
FY154_19025	COG4166	transmembrane transport
FY154_19030	COG0395	ABC-type sugar transport system, permease component
FY154_19045	COG1566	PFAM secretion protein HlyD family protein
FY154_19060	COG2207	Transcriptional regulator
FY154_19065	COG1309	transcriptional regulator
FY154_19070	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_19095	COG1846	Transcriptional regulator
FY154_19100	COG0583	DNA-binding transcription factor activity
FY154_19105	COG2828	Protein conserved in bacteria
FY154_19120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_19135	COG0840	transmembrane signaling receptor activity
FY154_19155	COG1215	transferase activity, transferring glycosyl groups
FY154_19185	COG0583	DNA-binding transcription factor activity
FY154_19190	COG0346	lactoylglutathione lyase activity
FY154_19205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY154_19225	COG0583	DNA-binding transcription factor activity
FY154_19230	COG0477	Major facilitator Superfamily
FY154_19240	COG2205	protein histidine kinase activity
FY154_19245	COG0745	RESPONSE REGULATOR receiver
FY154_19250	COG0671	phosphoesterase, PA-phosphatase related
FY154_19300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY154_19305	COG0156	8-amino-7-oxononanoate synthase activity
FY154_19310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY154_19315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY154_19320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY154_19335	COG0010	Belongs to the arginase family
FY154_19345	COG0697	spore germination
FY154_19350	COG0673	inositol 2-dehydrogenase activity
FY154_19375	COG0477	Major facilitator Superfamily
FY154_19390	COG2194	sulfuric ester hydrolase activity
FY154_19400	COG0583	DNA-binding transcription factor activity
FY154_19405	COG4774	siderophore transport
FY154_19420	COG1120	ATPase activity
FY154_19430	COG3474	cytochrome
FY154_19435	COG2137	regulation of response to DNA damage stimulus
FY154_19440	COG3386	PFAM SMP-30 Gluconolaconase
FY154_19450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_19455	COG1129	ABC transporter
FY154_19460	COG1879	ABC-type sugar transport system periplasmic component
FY154_19465	COG4585	Histidine kinase
FY154_19470	COG2197	response regulator
FY154_19480	COG2133	pyrroloquinoline quinone binding
FY154_19490	COG0500	methyltransferase
FY154_19495	COG0564	pseudouridine synthase activity
FY154_19510	COG3448	diguanylate cyclase activity
FY154_19510	COG4175	Glycine betaine
FY154_19515	COG4176	ABC-type proline glycine betaine transport system permease component
FY154_19530	COG4191	Histidine kinase
FY154_19530	COG0784	Response regulator, receiver
FY154_19535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY154_19540	COG0489	protein tyrosine kinase activity
FY154_19540	COG3206	protein involved in exopolysaccharide biosynthesis
FY154_19545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY154_19550	COG1215	transferase activity, transferring glycosyl groups
FY154_19555	COG1215	transferase activity, transferring glycosyl groups
FY154_19560	COG1215	transferase activity, transferring glycosyl groups
FY154_19565	COG0438	transferase activity, transferring glycosyl groups
FY154_19570	COG2273	Hydrolase Family 16
FY154_19575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY154_19580	COG2244	polysaccharide biosynthetic process
FY154_19585	COG0463	Glycosyl transferase, family 2
FY154_19590	COG2327	Polysaccharide pyruvyl transferase
FY154_19595	COG1215	transferase activity, transferring glycosyl groups
FY154_19615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY154_19620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_19635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY154_19635	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY154_19665	COG1523	belongs to the glycosyl hydrolase 13 family
FY154_19670	COG0033	Phosphoglucomutase
FY154_19675	COG0297	glycogen (starch) synthase activity
FY154_19680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY154_19685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY154_19690	COG0058	SHG alpha-glucan phosphorylase activity
FY154_19700	COG1794	racemase activity, acting on amino acids and derivatives
FY154_19705	COG1522	sequence-specific DNA binding
FY154_19715	COG2084	Dehydrogenase
FY154_19720	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_19725	COG1063	alcohol dehydrogenase
FY154_19735	COG4988	ABC transporter
FY154_19740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY154_19750	COG1294	oxidase, subunit
FY154_19780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY154_19785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY154_19815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY154_19820	COG0539	negative regulation of cytoplasmic translation
FY154_19850	COG4221	oxidoreductase activity
FY154_19860	COG0747	negative chemotaxis
FY154_19865	COG0601	transmembrane transport
FY154_19870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_19875	COG0444	Belongs to the ABC transporter superfamily
FY154_19880	COG4608	Belongs to the ABC transporter superfamily
FY154_19885	COG0246	Mannitol dehydrogenase
FY154_19900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_19945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY154_19950	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_19965	COG4993	Dehydrogenase
FY154_19970	COG3685	Protein conserved in bacteria
FY154_20000	COG0693	protein deglycase activity
FY154_20020	COG0189	ligase activity
FY154_20025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY154_20030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY154_20045	COG0435	Glutathione S-transferase
FY154_20050	COG0583	DNA-binding transcription factor activity
FY154_20055	COG1012	belongs to the aldehyde dehydrogenase family
FY154_20060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY154_20065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY154_20070	COG1116	anion transmembrane transporter activity
FY154_20080	COG1522	sequence-specific DNA binding
FY154_20095	COG0784	Response regulator, receiver
FY154_20115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY154_20130	COG0019	diaminopimelate decarboxylase activity
FY154_20145	COG0527	aspartate kinase activity
FY154_20155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY154_20160	COG2890	protein-(glutamine-N5) methyltransferase activity
FY154_20170	COG0542	response to heat
FY154_20175	COG1196	nuclear chromosome segregation
FY154_20175	COG0741	lytic transglycosylase activity
FY154_20175	COG0739	heme binding
FY154_20215	COG2376	Dihydroxyacetone kinase
FY154_20220	COG1522	sequence-specific DNA binding
FY154_20240	COG0431	NADPH-dependent FMN reductase
FY154_20250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_20260	COG4172	Belongs to the ABC transporter superfamily
FY154_20265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_20285	COG0277	FAD linked oxidase domain protein
FY154_20305	COG0778	Nitroreductase
FY154_20335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY154_20360	COG2318	DinB family
FY154_20365	COG0583	DNA-binding transcription factor activity
FY154_20380	COG1335	isochorismatase
FY154_20405	COG3842	ATPase activity
FY154_20410	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY154_20415	COG1177	transmembrane transport
FY154_20420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY154_20430	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY154_20445	COG1120	ATPase activity
FY154_20450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_20455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_20460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY154_20465	COG1629	transport
FY154_20465	COG4774	siderophore transport
FY154_20470	COG4702	Belongs to the UPF0303 family
FY154_20490	COG1024	Enoyl-CoA hydratase
FY154_20495	COG1012	belongs to the aldehyde dehydrogenase family
FY154_20500	COG1653	transport
FY154_20505	COG1175	transmembrane transport
FY154_20510	COG0395	ABC-type sugar transport system, permease component
FY154_20515	COG3842	ATPase activity
FY154_20540	COG3474	cytochrome
FY154_20545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY154_20550	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY154_20555	COG1845	cytochrome c oxidase, subunit III
FY154_20580	COG0577	efflux transmembrane transporter activity
FY154_20580	COG1136	(ABC) transporter
FY154_20635	COG3842	ATPase activity
FY154_20645	COG1177	transmembrane transport
FY154_20650	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY154_20665	COG1940	carbohydrate kinase activity
FY154_20685	COG1069	ribulokinase activity
FY154_20690	COG1349	DNA-binding transcription factor activity
FY154_20695	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_20720	COG0395	ABC-type sugar transport system, permease component
FY154_20730	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_20745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY154_20750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY154_20760	COG0477	Major facilitator Superfamily
FY154_20800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FY154_20810	COG1733	regulation of RNA biosynthetic process
FY154_20845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY154_20850	COG3938	Belongs to the proline racemase family
FY154_20855	COG4176	ABC-type proline glycine betaine transport system permease component
FY154_20860	COG4176	ABC-type proline glycine betaine transport system permease component
FY154_20865	COG4175	Glycine betaine
FY154_20865	COG3448	diguanylate cyclase activity
FY154_20875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_20880	COG1012	belongs to the aldehyde dehydrogenase family
FY154_20885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_20895	COG0047	phosphoribosylformylglycinamidine synthase activity
FY154_20900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_20910	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY154_20910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY154_20920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY154_20940	COG1309	transcriptional regulator
FY154_20955	COG1136	(ABC) transporter
FY154_20970	COG1063	alcohol dehydrogenase
FY154_20980	COG1879	ABC-type sugar transport system periplasmic component
FY154_20990	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_21010	COG0477	Major facilitator Superfamily
FY154_21150	COG5001	Diguanylate cyclase
FY154_21150	COG3300	MHYT domain
FY154_21175	COG1253	flavin adenine dinucleotide binding
FY154_21190	COG3842	ATPase activity
FY154_21195	COG0395	ABC-type sugar transport system, permease component
FY154_21200	COG1175	transmembrane transport
FY154_21205	COG1653	transport
FY154_21215	COG0673	inositol 2-dehydrogenase activity
FY154_21220	COG1609	Transcriptional regulator
FY154_21235	COG0583	DNA-binding transcription factor activity
FY154_21245	COG1879	ABC-type sugar transport system periplasmic component
FY154_21250	COG1129	ABC transporter
FY154_21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_21260	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_21265	COG1609	Transcriptional regulator
FY154_21275	COG0673	inositol 2-dehydrogenase activity
FY154_21335	COG0714	Associated with various cellular activities
FY154_21340	COG3256	nitric oxide reductase
FY154_21370	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY154_21375	COG3189	MarR family transcriptional regulator
FY154_21385	COG0826	peptidase U32
FY154_21410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY154_21420	COG4459	periplasmic nitrate reductase
FY154_21435	COG0243	molybdopterin cofactor binding
FY154_21445	COG3005	denitrification pathway
FY154_21450	COG0583	DNA-binding transcription factor activity
FY154_21460	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY154_21465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_21480	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_21485	COG1535	isochorismatase
FY154_21485	COG3433	isochorismatase activity
FY154_21490	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY154_21495	COG1169	isochorismate synthase
FY154_21505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY154_21505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY154_21510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY154_21520	COG2375	cellular response to nickel ion
FY154_21530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_21535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_21545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_21555	COG1629	transport
FY154_21555	COG4774	siderophore transport
FY154_21560	COG1960	acyl-CoA dehydrogenase activity
FY154_21565	COG0583	DNA-binding transcription factor activity
FY154_21570	COG1609	Transcriptional regulator
FY154_21580	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY154_21590	COG3842	ATPase activity
FY154_21600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY154_21605	COG0583	DNA-binding transcription factor activity
FY154_21610	COG2814	Major facilitator Superfamily
FY154_21615	COG1473	amidohydrolase
FY154_21620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY154_21630	COG0747	negative chemotaxis
FY154_21635	COG0601	transmembrane transport
FY154_21640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_21645	COG0444	Belongs to the ABC transporter superfamily
FY154_21650	COG4608	Belongs to the ABC transporter superfamily
FY154_21655	COG0583	DNA-binding transcription factor activity
FY154_21660	COG0747	negative chemotaxis
FY154_21665	COG0601	transmembrane transport
FY154_21670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_21675	COG0154	amidase activity
FY154_21680	COG0693	protein deglycase activity
FY154_21690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_21695	COG0601	transmembrane transport
FY154_21705	COG1473	amidohydrolase
FY154_21710	COG4172	Belongs to the ABC transporter superfamily
FY154_21715	COG2390	Transcriptional regulator
FY154_21725	COG1175	transmembrane transport
FY154_21730	COG0395	ABC-type sugar transport system, permease component
FY154_21755	COG1069	ribulokinase activity
FY154_21780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY154_21790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY154_21795	COG1414	Transcriptional regulator
FY154_21800	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_21810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY154_21815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY154_21820	COG1121	(ABC) transporter
FY154_21825	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY154_21835	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY154_21840	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY154_21845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY154_21850	COG0471	metal ion transport
FY154_21850	COG3273	potassium ion transport
FY154_21855	COG1253	flavin adenine dinucleotide binding
FY154_21860	COG1309	transcriptional regulator
FY154_21880	COG1609	Transcriptional regulator
FY154_21885	COG1070	Carbohydrate kinase
FY154_21890	COG2115	Belongs to the xylose isomerase family
FY154_21900	COG0778	Nitroreductase
FY154_21905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY154_21910	COG2011	ABC-type metal ion transport system permease component
FY154_21920	COG5001	Diguanylate cyclase
FY154_21920	COG3300	MHYT domain
FY154_21925	COG1054	Belongs to the UPF0176 family
FY154_21935	COG2954	triphosphatase activity
FY154_21940	COG0800	Aldolase
FY154_21960	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY154_21995	COG0523	cobalamin synthesis protein
FY154_22005	COG1846	Transcriptional regulator
FY154_22010	COG1609	Transcriptional regulator
FY154_22015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY154_22025	COG3718	enzyme involved in inositol metabolism
FY154_22035	COG3962	Belongs to the TPP enzyme family
FY154_22040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_22055	COG0411	ABC transporter
FY154_22070	COG0683	leucine binding
FY154_22085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_22095	COG0747	negative chemotaxis
FY154_22100	COG4172	Belongs to the ABC transporter superfamily
FY154_22120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY154_22125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY154_22130	COG1126	abc transporter atp-binding protein
FY154_22135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_22140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_22145	COG0765	amino acid transport
FY154_22150	COG0765	amino acid transport
FY154_22155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY154_22160	COG3485	protocatechuate 3,4-dioxygenase
FY154_22165	COG3485	protocatechuate 3,4-dioxygenase
FY154_22170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY154_22180	COG0583	DNA-binding transcription factor activity
FY154_22195	COG1414	Transcriptional regulator
FY154_22205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY154_22210	COG0183	Belongs to the thiolase family
FY154_22215	COG1609	Transcriptional regulator
FY154_22230	COG1082	Xylose isomerase domain protein TIM barrel
FY154_22235	COG0673	inositol 2-dehydrogenase activity
FY154_22245	COG1609	Transcriptional regulator
FY154_22250	COG0395	ABC-type sugar transport system, permease component
FY154_22255	COG1175	transmembrane transport
FY154_22260	COG3842	ATPase activity
FY154_22270	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY154_22290	COG2814	Major facilitator Superfamily
FY154_22295	COG4774	siderophore transport
FY154_22300	COG3712	iron ion homeostasis
FY154_22310	COG1940	carbohydrate kinase activity
FY154_22315	COG0584	glycerophosphoryl diester phosphodiesterase
FY154_22320	COG0300	oxidoreductase activity
FY154_22335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY154_22355	COG0667	Aldo Keto reductase
FY154_22360	COG0583	DNA-binding transcription factor activity
FY154_22370	COG1132	(ABC) transporter
FY154_22375	COG0275	rRNA processing
FY154_22385	COG0673	inositol 2-dehydrogenase activity
FY154_22410	COG3754	Rhamnan synthesis protein F
FY154_22425	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY154_22430	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY154_22435	COG1088	dTDP-glucose 4,6-dehydratase activity
FY154_22440	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY154_22445	COG0210	DNA helicase
FY154_22455	COG1609	Transcriptional regulator
FY154_22460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY154_22460	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY154_22475	COG0395	ABC-type sugar transport system, permease component
FY154_22480	COG3842	ATPase activity
FY154_22490	COG0444	Belongs to the ABC transporter superfamily
FY154_22495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_22500	COG0601	transmembrane transport
FY154_22505	COG2186	Transcriptional regulator
FY154_22525	COG3300	MHYT domain
FY154_22525	COG5001	Diguanylate cyclase
FY154_22530	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_22540	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY154_22550	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY154_22555	COG0306	phosphate transporter
FY154_22560	COG1392	Phosphate transport regulator
FY154_22575	COG1566	PFAM secretion protein HlyD family protein
FY154_22580	COG0745	RESPONSE REGULATOR receiver
FY154_22585	COG2205	protein histidine kinase activity
FY154_22600	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY154_22610	COG4774	siderophore transport
FY154_22620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_22625	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_22630	COG1120	ATPase activity
FY154_22635	COG0583	DNA-binding transcription factor activity
FY154_22645	COG3119	arylsulfatase activity
FY154_22650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY154_22655	COG3842	ATPase activity
FY154_22660	COG0165	Argininosuccinate lyase
FY154_22665	COG0395	ABC-type sugar transport system, permease component
FY154_22670	COG1175	transmembrane transport
FY154_22675	COG2182	Extracellular solute-binding protein
FY154_22680	COG1940	carbohydrate kinase activity
FY154_22705	COG1486	melibiose metabolic process
FY154_22710	COG0747	negative chemotaxis
FY154_22715	COG0601	transmembrane transport
FY154_22720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_22725	COG4172	Belongs to the ABC transporter superfamily
FY154_22730	COG1486	melibiose metabolic process
FY154_22735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY154_22740	COG0842	Transport permease protein
FY154_22740	COG1129	ABC transporter
FY154_22745	COG0842	Transport permease protein
FY154_22760	COG0784	Response regulator, receiver
FY154_22765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY154_22775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_22780	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY154_22795	COG0765	amino acid transport
FY154_22805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY154_22815	COG3938	Belongs to the proline racemase family
FY154_22830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_22835	COG0765	amino acid transport
FY154_22840	COG0765	amino acid transport
FY154_22850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY154_22865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY154_22885	COG3383	formate dehydrogenase (NAD+) activity
FY154_22895	COG2223	nitrite transmembrane transporter activity
FY154_22900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY154_22910	COG2186	Transcriptional regulator
FY154_22915	COG0747	negative chemotaxis
FY154_22920	COG0601	transmembrane transport
FY154_22925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_22930	COG4172	Belongs to the ABC transporter superfamily
FY154_22935	COG4948	Mandelate Racemase Muconate Lactonizing
FY154_22945	COG2186	Transcriptional regulator
FY154_22950	COG0747	negative chemotaxis
FY154_22955	COG0601	transmembrane transport
FY154_22960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_22965	COG0405	Gamma-glutamyltransferase
FY154_22975	COG0483	inositol monophosphate 1-phosphatase activity
FY154_22985	COG3842	ATPase activity
FY154_22990	COG0395	ABC-type sugar transport system, permease component
FY154_23010	COG3237	CsbD-like
FY154_23020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY154_23025	COG3181	Tripartite tricarboxylate transporter family receptor
FY154_23030	COG5265	(ABC) transporter
FY154_23035	COG0488	(ABC) transporter
FY154_23060	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY154_23065	COG0110	maltose O-acetyltransferase activity
FY154_23075	COG1063	alcohol dehydrogenase
FY154_23080	COG3284	Transcriptional regulator
FY154_23100	COG1129	ABC transporter
FY154_23105	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_23110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_23120	COG0572	uridine kinase
FY154_23125	COG1082	Xylose isomerase domain protein TIM barrel
FY154_23150	COG4178	(ABC) transporter
FY154_23185	COG0640	Transcriptional regulator
FY154_23200	COG2274	protein secretion by the type I secretion system
FY154_23215	COG1192	Involved in chromosome partitioning
FY154_23220	COG1475	DNA binding
FY154_23225	COG0640	Transcriptional regulator
FY154_23240	COG1126	abc transporter atp-binding protein
FY154_23245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY154_23250	COG1609	Transcriptional regulator
FY154_23285	COG3239	Fatty acid desaturase
FY154_23295	COG1278	Cold shock
FY154_23370	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY154_23370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY154_23405	COG4191	Histidine kinase
FY154_23410	COG1132	(ABC) transporter
FY154_23420	COG0640	Transcriptional regulator
FY154_23450	COG4977	sequence-specific DNA binding
FY154_23455	COG2211	Major facilitator Superfamily
FY154_23460	COG2807	transmembrane transport
FY154_23465	COG1846	Transcriptional regulator
FY154_23480	COG2814	Major facilitator Superfamily
FY154_23510	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY154_23525	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY154_23530	COG0583	DNA-binding transcription factor activity
FY154_23545	COG0071	Belongs to the small heat shock protein (HSP20) family
FY154_23590	COG3838	Conjugal transfer protein Trbc
FY154_23595	COG3702	type iv secretory pathway
FY154_23600	COG3451	type IV secretory pathway VirB4
FY154_23615	COG3704	protein secretion by the type IV secretion system
FY154_23625	COG3736	Type IV secretory pathway, component VirB8
FY154_23630	COG3504	Conjugal transfer protein
FY154_23635	COG2948	multi-organism process
FY154_23640	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY154_23740	COG3831	ATPase activity
FY154_23755	COG3505	Type IV secretory pathway VirD4
FY154_23780	COG0583	DNA-binding transcription factor activity
FY154_23820	COG0745	RESPONSE REGULATOR receiver
FY154_23860	COG3842	ATPase activity
FY154_23865	COG4208	sulfate ABC transporter
FY154_23870	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY154_23890	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY154_23895	COG1942	4-Oxalocrotonate Tautomerase
FY154_23905	COG3971	2-oxopent-4-enoate hydratase activity
FY154_23915	COG1414	Transcriptional regulator
FY154_23925	COG1137	ATPase activity
FY154_23940	COG4177	L-phenylalanine transmembrane transporter activity
FY154_23960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY154_23965	COG1175	transmembrane transport
FY154_23970	COG0395	ABC-type sugar transport system, permease component
FY154_23980	COG0366	Alpha amylase catalytic
FY154_23985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY154_23990	COG1082	Xylose isomerase domain protein TIM barrel
FY154_23995	COG3842	ATPase activity
FY154_24005	COG1940	carbohydrate kinase activity
FY154_24010	COG0395	ABC-type sugar transport system, permease component
FY154_24020	COG2182	Extracellular solute-binding protein
FY154_24025	COG0673	inositol 2-dehydrogenase activity
FY154_24055	COG1126	abc transporter atp-binding protein
FY154_24060	COG0765	amino acid transport
FY154_24065	COG0765	amino acid transport
FY154_24075	COG4608	Belongs to the ABC transporter superfamily
FY154_24085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_24100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY154_24105	COG0583	DNA-binding transcription factor activity
FY154_24110	COG2423	ornithine cyclodeaminase activity
FY154_24120	COG1957	nucleoside hydrolase
FY154_24140	COG1335	isochorismatase
FY154_24145	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_24190	COG0583	DNA-binding transcription factor activity
FY154_24195	COG1902	pentaerythritol trinitrate reductase activity
FY154_24200	COG0583	DNA-binding transcription factor activity
FY154_24205	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_24215	COG1335	isochorismatase
FY154_24220	COG0583	DNA-binding transcription factor activity
FY154_24230	COG1695	Transcriptional regulator
FY154_24310	COG2207	Transcriptional regulator
FY154_24355	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_24370	COG1802	Transcriptional regulator
FY154_24375	COG3485	protocatechuate 3,4-dioxygenase
FY154_24380	COG3971	2-oxopent-4-enoate hydratase activity
FY154_24395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY154_24400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY154_24415	COG1063	alcohol dehydrogenase
FY154_24425	COG1960	acyl-CoA dehydrogenase activity
FY154_24430	COG1024	Enoyl-CoA hydratase
FY154_24440	COG1012	belongs to the aldehyde dehydrogenase family
FY154_24445	COG0477	Major facilitator Superfamily
FY154_24460	COG3706	GGDEF domain
FY154_24480	COG1846	Transcriptional regulator
FY154_24520	COG1012	belongs to the aldehyde dehydrogenase family
FY154_24530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY154_24540	COG3386	PFAM SMP-30 Gluconolaconase
FY154_24545	COG3622	Belongs to the hyi family
FY154_24550	COG2084	Dehydrogenase
FY154_24580	COG1940	carbohydrate kinase activity
FY154_24585	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY154_24595	COG1129	ABC transporter
FY154_24615	COG0583	DNA-binding transcription factor activity
FY154_24620	COG2271	Major facilitator Superfamily
FY154_24630	COG2272	Belongs to the type-B carboxylesterase lipase family
FY154_24650	COG1129	ABC transporter
FY154_24675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY154_24685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY154_24720	COG0583	DNA-binding transcription factor activity
FY154_24725	COG1414	Transcriptional regulator
FY154_24735	COG4948	Mandelate Racemase Muconate Lactonizing
FY154_24745	COG3842	ATPase activity
FY154_24750	COG1175	transmembrane transport
FY154_24755	COG0395	ABC-type sugar transport system, permease component
FY154_24765	COG0477	Major facilitator Superfamily
FY154_24800	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY154_24820	COG0747	negative chemotaxis
FY154_24830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_24845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY154_24855	COG4215	(ABC) transporter
FY154_24910	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY154_24915	COG0251	oxidation-reduction process
FY154_24920	COG3547	Transposase (IS116 IS110 IS902 family)
FY154_24955	COG1028	Short-chain dehydrogenase reductase Sdr
FY154_24960	COG1335	isochorismatase
FY154_24970	COG1309	transcriptional regulator
FY154_24975	COG4604	ABC transporter, ATP-binding protein
FY154_24980	COG4605	iron ion homeostasis
FY154_24985	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY154_24995	COG2132	Multicopper oxidase
FY154_25000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY154_25005	COG4771	TonB-dependent receptor
FY154_25040	COG1695	Transcriptional regulator
FY154_25075	COG2132	Multicopper oxidase
FY154_25110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY154_25130	COG1192	Involved in chromosome partitioning
FY154_25135	COG1475	DNA binding
FY154_25140	COG0640	Transcriptional regulator
FY154_25145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY154_25175	COG2211	Major facilitator Superfamily
FY154_25220	COG4974	Belongs to the 'phage' integrase family
FY154_25225	COG1051	belongs to the nudix hydrolase family
FY154_25265	COG1475	DNA binding
FY154_25290	COG2824	Alkylphosphonate utilization operon protein PhnA
FY154_25310	COG1280	lysine exporter protein (LysE YggA)
FY154_25375	COG5489	Protein of unknown function (DUF736)
FY154_25460	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY154_25475	COG0747	negative chemotaxis
FY154_25495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_25500	COG0584	glycerophosphoryl diester phosphodiesterase
FY154_25505	COG0483	inositol monophosphate 1-phosphatase activity
FY154_25570	COG3161	chorismate lyase activity
FY154_25720	COG3436	PFAM IS66 Orf2 family protein
FY154_25815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY154_25845	COG0583	DNA-binding transcription factor activity
FY154_25850	COG0747	negative chemotaxis
FY154_25865	COG0252	asparaginase activity
FY154_25870	COG0583	DNA-binding transcription factor activity
FY154_25890	COG3842	ATPase activity
FY154_25915	COG3701	Conjugal transfer protein
FY154_25920	COG3846	protein secretion by the type IV secretion system
FY154_25930	COG5314	conjugation
FY154_25935	COG3451	type IV secretory pathway VirB4
FY154_25950	COG4962	Type ii secretion system protein e