locus-tag	class	description
FY131_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY131_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY131_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY131_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY131_00025	COG1420	regulation of RNA biosynthetic process
FY131_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY131_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY131_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY131_00050	COG1137	ATPase activity
FY131_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY131_00065	COG0616	signal peptide processing
FY131_00070	COG0776	regulation of translation
FY131_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY131_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY131_00095	COG5002	protein histidine kinase activity
FY131_00095	COG2205	protein histidine kinase activity
FY131_00095	COG0784	Response regulator, receiver
FY131_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY131_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY131_00115	COG0728	peptidoglycan biosynthetic process
FY131_00125	COG0180	Tryptophanyl-tRNA synthetase
FY131_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY131_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY131_00145	COG0456	acetyltransferase
FY131_00145	COG1214	PFAM Peptidase M22, glycoprotease
FY131_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY131_00165	COG1702	phosphate starvation-inducible protein PhoH
FY131_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY131_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY131_00185	COG1396	sequence-specific DNA binding
FY131_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY131_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY131_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_00210	COG0242	peptide deformylase activity
FY131_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY131_00220	COG0101	tRNA pseudouridine synthase activity
FY131_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY131_00235	COG2171	N-acyltransferase activity
FY131_00245	COG0840	transmembrane signaling receptor activity
FY131_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY131_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY131_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY131_00295	COG0706	membrane insertase activity
FY131_00300	COG0594	ribonuclease P activity
FY131_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY131_00310	COG0840	transmembrane signaling receptor activity
FY131_00325	COG2226	methyltransferase
FY131_00330	COG3842	ATPase activity
FY131_00335	COG1175	transmembrane transport
FY131_00340	COG0395	ABC-type sugar transport system, permease component
FY131_00355	COG0427	acetyl-CoA hydrolase
FY131_00365	COG3938	Belongs to the proline racemase family
FY131_00370	COG0418	dihydroorotase activity
FY131_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY131_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY131_00400	COG0166	Belongs to the GPI family
FY131_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY131_00410	COG3842	ATPase activity
FY131_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY131_00425	COG4774	siderophore transport
FY131_00465	COG2326	polyphosphate kinase activity
FY131_00470	COG5002	protein histidine kinase activity
FY131_00475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY131_00480	COG0573	inorganic phosphate transmembrane transporter activity
FY131_00490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY131_00495	COG0704	Plays a role in the regulation of phosphate uptake
FY131_00500	COG0745	RESPONSE REGULATOR receiver
FY131_00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY131_00515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY131_00525	COG2967	ApaG domain
FY131_00540	COG0717	Belongs to the dCTP deaminase family
FY131_00550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY131_00600	COG0167	dihydroorotate dehydrogenase activity
FY131_00615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY131_00635	COG1959	2 iron, 2 sulfur cluster binding
FY131_00640	COG1201	RNA secondary structure unwinding
FY131_00670	COG1960	acyl-CoA dehydrogenase activity
FY131_00675	COG0183	Belongs to the thiolase family
FY131_00680	COG1024	Enoyl-CoA hydratase
FY131_00680	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY131_00720	COG1320	monovalent cation:proton antiporter activity
FY131_00725	COG2212	antiporter activity
FY131_00730	COG1863	multisubunit Na H antiporter MnhE subunit
FY131_00735	COG0651	ATP synthesis coupled electron transport
FY131_00740	COG1006	Multisubunit Na H antiporter MnhC subunit
FY131_00745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY131_00745	COG2111	Na H antiporter
FY131_00755	COG0840	transmembrane signaling receptor activity
FY131_00765	COG0745	RESPONSE REGULATOR receiver
FY131_00770	COG2198	Histidine kinase
FY131_00770	COG0643	Histidine kinase
FY131_00775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY131_00780	COG2201	protein-glutamate methylesterase activity
FY131_00785	COG0745	RESPONSE REGULATOR receiver
FY131_00790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY131_00800	COG1766	The M ring may be actively involved in energy transduction
FY131_00805	COG2771	luxR family
FY131_00815	COG0840	transmembrane signaling receptor activity
FY131_00815	COG2972	Histidine kinase
FY131_00820	COG0784	Response regulator, receiver
FY131_00820	COG2198	Histidine kinase
FY131_00820	COG2205	protein histidine kinase activity
FY131_00825	COG1970	mechanosensitive ion channel activity
FY131_00830	COG0436	Aminotransferase
FY131_00845	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY131_00850	COG0424	maF-like protein
FY131_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY131_00865	COG5328	Belongs to the UPF0262 family
FY131_00870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY131_00880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY131_00895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY131_00910	COG1338	Plays a role in the flagellum-specific transport system
FY131_00920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY131_00930	COG1706	bacterial-type flagellum-dependent cell motility
FY131_00935	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY131_00940	COG4786	Flagellar basal body rod
FY131_00945	COG1677	Flagellar hook-basal body complex protein FliE
FY131_00950	COG1558	bacterial-type flagellum-dependent cell motility
FY131_00955	COG1815	bacterial-type flagellum-dependent cell motility
FY131_00965	COG1157	protein secretion by the type III secretion system
FY131_00970	COG4786	Flagellar basal body rod
FY131_00980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY131_00985	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY131_00990	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY131_00995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY131_01000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY131_01020	COG1360	Flagellar Motor Protein
FY131_01045	COG1749	Flagellar hook protein flgE
FY131_01065	COG5443	negative regulation of bacterial-type flagellum assembly
FY131_01070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY131_01080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY131_01120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY131_01125	COG1609	Transcriptional regulator
FY131_01130	COG1653	transport
FY131_01135	COG1175	transmembrane transport
FY131_01140	COG0395	ABC-type sugar transport system, permease component
FY131_01145	COG0366	Alpha amylase catalytic
FY131_01150	COG3842	ATPase activity
FY131_01165	COG0129	dihydroxy-acid dehydratase activity
FY131_01170	COG0363	glucosamine-6-phosphate deaminase activity
FY131_01175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY131_01185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_01195	COG2081	HI0933 family
FY131_01215	COG2224	Isocitrate lyase
FY131_01230	COG3842	ATPase activity
FY131_01235	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY131_01240	COG1177	transmembrane transport
FY131_01250	COG2205	protein histidine kinase activity
FY131_01260	COG0248	Ppx GppA phosphatase
FY131_01265	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY131_01270	COG0477	Major facilitator Superfamily
FY131_01300	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY131_01305	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY131_01315	COG0142	geranyltranstransferase activity
FY131_01340	COG0752	glycyl-tRNA synthetase alpha subunit
FY131_01350	COG1704	LemA family
FY131_01355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY131_01365	COG0751	glycine-tRNA ligase activity
FY131_01385	COG0840	transmembrane signaling receptor activity
FY131_01395	COG0151	Belongs to the GarS family
FY131_01400	COG2183	response to ionizing radiation
FY131_01405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY131_01430	COG0583	DNA-binding transcription factor activity
FY131_01450	COG0306	phosphate transporter
FY131_01460	COG0561	phosphatase activity
FY131_01465	COG0438	transferase activity, transferring glycosyl groups
FY131_01470	COG2186	Transcriptional regulator
FY131_01480	COG0583	DNA-binding transcription factor activity
FY131_01485	COG0277	FAD linked oxidase domain protein
FY131_01490	COG0277	FAD linked oxidase domain protein
FY131_01495	COG0247	lactate metabolic process
FY131_01505	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_01510	COG2818	Glycosylase
FY131_01520	COG2855	membrane
FY131_01525	COG0583	DNA-binding transcription factor activity
FY131_01545	COG0124	histidyl-tRNA synthetase
FY131_01555	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY131_01560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY131_01565	COG2259	Doxx family
FY131_01575	COG0459	protein refolding
FY131_01580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY131_01590	COG0196	riboflavin kinase activity
FY131_01595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY131_01605	COG0590	tRNA wobble adenosine to inosine editing
FY131_01610	COG1187	pseudouridine synthase activity
FY131_01615	COG0742	ribosomal rna small subunit methyltransferase
FY131_01620	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY131_01630	COG0312	modulator of DNA gyrase
FY131_01645	COG1519	Transferase
FY131_01655	COG1663	tetraacyldisaccharide 4'-kinase activity
FY131_01665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY131_01670	COG2205	protein histidine kinase activity
FY131_01670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_01675	COG3300	MHYT domain
FY131_01675	COG5001	Diguanylate cyclase
FY131_01680	COG3386	PFAM SMP-30 Gluconolaconase
FY131_01685	COG0800	Aldolase
FY131_01690	COG3734	2-keto-3-deoxy-galactonokinase
FY131_01695	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_01705	COG2197	response regulator
FY131_01720	COG0598	Magnesium transport protein CorA
FY131_01725	COG3158	transport of potassium into the cell
FY131_01740	COG0356	it plays a direct role in the translocation of protons across the membrane
FY131_01750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY131_01755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY131_01765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY131_01785	COG0009	L-threonylcarbamoyladenylate synthase
FY131_01795	COG4638	Rieske (2fe-2S)
FY131_01820	COG1960	acyl-CoA dehydrogenase activity
FY131_01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY131_01840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY131_01845	COG0840	transmembrane signaling receptor activity
FY131_01870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY131_01875	COG1741	Belongs to the pirin family
FY131_01880	COG1722	exodeoxyribonuclease VII activity
FY131_01885	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY131_01890	COG1268	BioY protein
FY131_01895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY131_01900	COG1122	ATPase activity
FY131_01905	COG3214	Protein conserved in bacteria
FY131_01910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY131_01910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY131_01915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY131_01935	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY131_01940	COG0484	heat shock protein binding
FY131_01950	COG0259	pyridoxamine-phosphate oxidase activity
FY131_01965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY131_01975	COG0312	modulator of DNA gyrase
FY131_01990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY131_01995	COG0109	protoheme IX farnesyltransferase activity
FY131_02000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY131_02015	COG3346	SURF1 family
FY131_02020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY131_02025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY131_02030	COG0328	RNA-DNA hybrid ribonuclease activity
FY131_02040	COG0678	peroxiredoxin activity
FY131_02040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY131_02050	COG1678	Uncharacterized ACR, COG1678
FY131_02070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY131_02075	COG0612	Peptidase, M16
FY131_02090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY131_02110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY131_02120	COG1194	a g-specific adenine glycosylase
FY131_02130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY131_02135	COG1196	nuclear chromosome segregation
FY131_02140	COG2514	catechol 2,3-dioxygenase activity
FY131_02145	COG0574	Belongs to the PEP-utilizing enzyme family
FY131_02145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY131_02160	COG1823	symporter activity
FY131_02180	COG0579	oxidoreductase
FY131_02205	COG2895	sulfate adenylyltransferase (ATP) activity
FY131_02210	COG0175	sulfate reduction
FY131_02215	COG0175	sulfate reduction
FY131_02220	COG1959	2 iron, 2 sulfur cluster binding
FY131_02225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY131_02230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY131_02235	COG4208	sulfate ABC transporter
FY131_02240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY131_02250	COG2199	diguanylate cyclase activity
FY131_02250	COG2203	Gaf domain
FY131_02250	COG2200	EAL domain
FY131_02260	COG1309	transcriptional regulator
FY131_02265	COG1012	belongs to the aldehyde dehydrogenase family
FY131_02270	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY131_02315	COG0477	Major facilitator Superfamily
FY131_02325	COG1793	dna ligase
FY131_02325	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY131_02340	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_02345	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_02360	COG1846	Transcriptional regulator
FY131_02365	COG1764	response to oxidative stress
FY131_02380	COG0488	(ABC) transporter
FY131_02415	COG0583	DNA-binding transcription factor activity
FY131_02420	COG4221	oxidoreductase activity
FY131_02430	COG0433	COG0433 Predicted ATPase
FY131_02440	COG1733	regulation of RNA biosynthetic process
FY131_02445	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY131_02455	COG1280	lysine exporter protein (LysE YggA)
FY131_02460	COG0656	L-ascorbic acid biosynthetic process
FY131_02465	COG2378	regulation of single-species biofilm formation
FY131_02475	COG4106	trans-aconitate 2-methyltransferase activity
FY131_02480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY131_02485	COG0840	transmembrane signaling receptor activity
FY131_02490	COG0583	DNA-binding transcription factor activity
FY131_02505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY131_02525	COG3909	cytochrome
FY131_02530	COG2010	Cytochrome c
FY131_02560	COG0789	Transcriptional regulator
FY131_02590	COG4176	ABC-type proline glycine betaine transport system permease component
FY131_02615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_02625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY131_02625	COG2169	Transcriptional regulator
FY131_02635	COG2514	catechol 2,3-dioxygenase activity
FY131_02655	COG1272	protein, Hemolysin III
FY131_02665	COG1280	lysine exporter protein (LysE YggA)
FY131_02670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY131_02675	COG2111	Na H antiporter
FY131_02675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY131_02680	COG2111	Na H antiporter
FY131_02685	COG1006	Multisubunit Na H antiporter MnhC subunit
FY131_02690	COG0651	ATP synthesis coupled electron transport
FY131_02695	COG1863	multisubunit Na H antiporter MnhE subunit
FY131_02700	COG2212	antiporter activity
FY131_02705	COG1320	monovalent cation:proton antiporter activity
FY131_02710	COG4957	zinc ion binding
FY131_02725	COG2166	iron-sulfur cluster assembly
FY131_02735	COG2205	protein histidine kinase activity
FY131_02790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY131_02795	COG2983	Belongs to the UPF0260 family
FY131_02825	COG1621	beta-fructofuranosidase activity
FY131_02830	COG2202	Pas domain
FY131_02830	COG3920	Histidine kinase
FY131_02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY131_02885	COG4695	Portal protein
FY131_02990	COG4235	cytochrome complex assembly
FY131_02995	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY131_03000	COG1138	Cytochrome C-type biogenesis protein
FY131_03005	COG3088	subunit of a heme lyase
FY131_03010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY131_03015	COG0745	RESPONSE REGULATOR receiver
FY131_03025	COG3011	Protein conserved in bacteria
FY131_03035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY131_03040	COG2202	Pas domain
FY131_03040	COG2205	protein histidine kinase activity
FY131_03050	COG0308	aminopeptidase N
FY131_03070	COG0443	Heat shock 70 kDa protein
FY131_03080	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_03105	COG0604	alcohol dehydrogenase
FY131_03110	COG1733	regulation of RNA biosynthetic process
FY131_03115	COG1968	undecaprenyl-diphosphatase activity
FY131_03120	COG2239	Acts as a magnesium transporter
FY131_03125	COG2814	Major facilitator Superfamily
FY131_03145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY131_03170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY131_03210	COG0741	lytic transglycosylase activity
FY131_03215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_03220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY131_03225	COG0840	transmembrane signaling receptor activity
FY131_03235	COG1758	RNA polymerase activity
FY131_03255	COG0736	holo-[acyl-carrier-protein] synthase activity
FY131_03260	COG0681	Belongs to the peptidase S26 family
FY131_03265	COG0571	ribonuclease III activity
FY131_03270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY131_03275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY131_03280	COG0784	Response regulator, receiver
FY131_03285	COG1381	Involved in DNA repair and RecF pathway recombination
FY131_03295	COG2226	methyltransferase
FY131_03305	COG1418	mRNA catabolic process
FY131_03315	COG0346	lactoylglutathione lyase activity
FY131_03330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_03335	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY131_03340	COG0668	transmembrane transport
FY131_03350	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY131_03355	COG0354	folic acid binding
FY131_03380	COG1742	UPF0060 membrane protein
FY131_03395	COG1183	phosphatidylcholine synthase activity
FY131_03400	COG0688	phosphatidylethanolamine metabolic process
FY131_03405	COG5265	(ABC) transporter
FY131_03450	COG2852	Protein conserved in bacteria
FY131_03455	COG0215	cysteine-tRNA ligase activity
FY131_03460	COG4221	oxidoreductase activity
FY131_03465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY131_03470	COG1286	toxin biosynthetic process
FY131_03485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY131_03495	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY131_03505	COG0305	Participates in initiation and elongation during chromosome replication
FY131_03530	COG0359	binds to the 23S rRNA
FY131_03540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY131_03545	COG0360	Binds together with S18 to 16S ribosomal RNA
FY131_03550	COG0667	Aldo Keto reductase
FY131_03555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY131_03565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY131_03570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY131_03575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY131_03580	COG1561	YicC-like family, N-terminal region
FY131_03585	COG0194	GDP metabolic process
FY131_03595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY131_03600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY131_03610	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY131_03625	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY131_03650	COG0488	(ABC) transporter
FY131_03655	COG3706	GGDEF domain
FY131_03665	COG0105	UTP biosynthetic process
FY131_03685	COG0314	molybdopterin synthase activity
FY131_03695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY131_03700	COG0322	excinuclease ABC activity
FY131_03705	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_03715	COG0625	glutathione transferase activity
FY131_03730	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY131_03735	COG0243	molybdopterin cofactor binding
FY131_03750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY131_03755	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY131_03760	COG0628	permease
FY131_03770	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY131_03775	COG0248	Ppx GppA phosphatase
FY131_03800	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY131_03810	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY131_03815	COG0477	Major facilitator Superfamily
FY131_03820	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY131_03825	COG4452	Inner membrane protein CreD
FY131_03830	COG0659	secondary active sulfate transmembrane transporter activity
FY131_03840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY131_03850	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY131_03860	COG0113	porphobilinogen synthase activity
FY131_03880	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY131_03885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY131_03890	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY131_03890	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY131_03900	COG1280	lysine exporter protein (LysE YggA)
FY131_03905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY131_03910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY131_03915	COG2814	Major facilitator Superfamily
FY131_03920	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY131_03940	COG0416	fatty acid biosynthetic process
FY131_03945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY131_03950	COG0776	regulation of translation
FY131_03980	COG0789	Transcriptional regulator
FY131_03985	COG0601	transmembrane transport
FY131_03990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_03995	COG0444	Belongs to the ABC transporter superfamily
FY131_04005	COG0747	negative chemotaxis
FY131_04015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY131_04020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY131_04035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY131_04040	COG0583	DNA-binding transcription factor activity
FY131_04050	COG0737	Belongs to the 5'-nucleotidase family
FY131_04075	COG2897	thiosulfate sulfurtransferase activity
FY131_04090	COG0415	Belongs to the DNA photolyase family
FY131_04100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY131_04130	COG3932	Exopolysaccharide synthesis, ExoD
FY131_04135	COG1238	metal cluster binding
FY131_04150	COG4139	cobalamin transport
FY131_04155	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY131_04165	COG1528	Iron-storage protein
FY131_04230	COG1612	heme a metabolic process
FY131_04240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY131_04245	COG0010	Belongs to the arginase family
FY131_04250	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY131_04255	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY131_04270	COG1832	CoA-binding protein
FY131_04290	COG2199	diguanylate cyclase activity
FY131_04295	COG0740	serine-type endopeptidase activity
FY131_04300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY131_04305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY131_04340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY131_04345	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY131_04350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY131_04360	COG0649	NAD binding
FY131_04370	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY131_04375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY131_04385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY131_04390	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY131_04400	COG0713	ATP synthesis coupled electron transport
FY131_04415	COG1007	ATP synthesis coupled electron transport
FY131_04420	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY131_04420	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY131_04435	COG0442	prolyl-tRNA aminoacylation
FY131_04445	COG1136	(ABC) transporter
FY131_04460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY131_04470	COG0784	Response regulator, receiver
FY131_04480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY131_04485	COG0477	Major facilitator Superfamily
FY131_04500	COG0557	exoribonuclease II activity
FY131_04505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY131_04520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY131_04530	COG0540	Belongs to the ATCase OTCase family
FY131_04535	COG1960	acyl-CoA dehydrogenase activity
FY131_04540	COG0456	acetyltransferase
FY131_04560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY131_04565	COG2824	Alkylphosphonate utilization operon protein PhnA
FY131_04570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY131_04575	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY131_04580	COG0154	amidase activity
FY131_04585	COG3811	Belongs to the UPF0386 family
FY131_04600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY131_04610	COG0456	acetyltransferase
FY131_04625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY131_04635	COG0511	ligase activity, forming carbon-carbon bonds
FY131_04640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY131_04650	COG0436	Aminotransferase
FY131_04670	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_04675	COG1530	ribonuclease E activity
FY131_04685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY131_04705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY131_04710	COG0384	phenazine biosynthesis protein PhzF
FY131_04725	COG0633	Ferredoxin
FY131_04740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY131_04745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY131_04755	COG3768	UPF0283 membrane protein
FY131_04760	COG3106	COG3106 Predicted ATPase
FY131_04790	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY131_04825	COG0537	adenosine 5'-monophosphoramidase activity
FY131_04850	COG0052	Belongs to the universal ribosomal protein uS2 family
FY131_04855	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY131_04860	COG0528	UMP kinase activity
FY131_04865	COG0233	cytoplasmic translational termination
FY131_04870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY131_04880	COG0750	zinc metalloprotease
FY131_04885	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY131_04890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY131_04895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY131_04900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY131_04905	COG3494	Protein of unknown function (DUF1009)
FY131_04910	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY131_04915	COG0372	Belongs to the citrate synthase family
FY131_04930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY131_04940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY131_04945	COG0148	phosphopyruvate hydratase activity
FY131_04955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY131_04960	COG0022	dehydrogenase e1 component
FY131_04960	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY131_04965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY131_04975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY131_04985	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY131_04990	COG0697	spore germination
FY131_05005	COG2867	negative regulation of translational initiation
FY131_05010	COG1546	Belongs to the CinA family
FY131_05015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY131_05015	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY131_05025	COG3852	Histidine kinase
FY131_05030	COG2204	response regulator
FY131_05035	COG5000	phosphorelay sensor kinase activity
FY131_05040	COG2204	response regulator
FY131_05045	COG0569	domain protein
FY131_05050	COG1923	regulation of RNA biosynthetic process
FY131_05055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY131_05060	COG3956	TIGRFAM MazG family protein
FY131_05070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY131_05070	COG1648	precorrin-2 dehydrogenase activity
FY131_05110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY131_05110	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY131_05115	COG0509	glycine decarboxylation via glycine cleavage system
FY131_05120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY131_05150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY131_05155	COG0564	pseudouridine synthase activity
FY131_05160	COG0546	phosphoglycolate phosphatase activity
FY131_05190	COG1671	Belongs to the UPF0178 family
FY131_05200	COG0450	alkyl hydroperoxide reductase
FY131_05205	COG0625	glutathione transferase activity
FY131_05245	COG2801	Transposase and inactivated derivatives
FY131_05255	COG0583	DNA-binding transcription factor activity
FY131_05260	COG2828	Protein conserved in bacteria
FY131_05275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_05280	COG0784	Response regulator, receiver
FY131_05280	COG4191	Histidine kinase
FY131_05285	COG0784	Response regulator, receiver
FY131_05290	COG2202	Pas domain
FY131_05290	COG3920	Histidine kinase
FY131_05295	COG0784	Response regulator, receiver
FY131_05295	COG4191	Histidine kinase
FY131_05325	COG0673	inositol 2-dehydrogenase activity
FY131_05335	COG1609	Transcriptional regulator
FY131_05340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_05345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_05350	COG1129	ABC transporter
FY131_05355	COG1879	ABC-type sugar transport system periplasmic component
FY131_05360	COG0328	RNA-DNA hybrid ribonuclease activity
FY131_05370	COG2226	methyltransferase
FY131_05380	COG0321	lipoyl(octanoyl) transferase activity
FY131_05380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY131_05385	COG0084	hydrolase, TatD family'
FY131_05390	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY131_05400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY131_05425	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY131_05435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY131_05485	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY131_05490	COG2095	MarC family integral membrane protein
FY131_05495	COG0517	IMP dehydrogenase activity
FY131_05495	COG0617	tRNA 3'-terminal CCA addition
FY131_05495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY131_05500	COG0629	single-stranded DNA binding
FY131_05505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY131_05515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY131_05525	COG3685	Protein conserved in bacteria
FY131_05530	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY131_05545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY131_05550	COG1121	(ABC) transporter
FY131_05570	COG0667	Aldo Keto reductase
FY131_05580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY131_05655	COG2239	Acts as a magnesium transporter
FY131_05660	COG0243	molybdopterin cofactor binding
FY131_05670	COG0242	peptide deformylase activity
FY131_05690	COG0321	lipoyl(octanoyl) transferase activity
FY131_05695	COG1064	alcohol dehydrogenase
FY131_05725	COG1862	Preprotein translocase
FY131_05745	COG2124	cytochrome p450
FY131_05760	COG0596	Alpha beta hydrolase
FY131_05770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY131_05775	COG0626	cystathionine gamma-synthase activity
FY131_05780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_05785	COG4597	amino acid ABC transporter
FY131_05790	COG0765	amino acid transport
FY131_05795	COG1126	abc transporter atp-binding protein
FY131_05810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY131_05825	COG0436	Aminotransferase
FY131_05855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY131_05870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY131_05875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY131_05880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY131_05895	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY131_05900	COG1489	DNA binding
FY131_05905	COG0024	Methionine aminopeptidase
FY131_05910	COG2003	Belongs to the UPF0758 family
FY131_05925	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY131_05940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY131_05945	COG0546	phosphoglycolate phosphatase activity
FY131_05960	COG0114	fumarate hydratase activity
FY131_05970	COG0504	CTP synthase activity
FY131_05980	COG0149	triose-phosphate isomerase activity
FY131_05990	COG0187	DNA topoisomerase II activity
FY131_05995	COG0740	serine-type endopeptidase activity
FY131_06005	COG0640	Transcriptional regulator
FY131_06010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY131_06015	COG0745	RESPONSE REGULATOR receiver
FY131_06030	COG3264	Mechanosensitive ion channel
FY131_06030	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY131_06095	COG1127	ABC transporter
FY131_06100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY131_06105	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_06115	COG0280	phosphate acetyltransferase
FY131_06115	COG0281	malic enzyme
FY131_06125	COG0778	Nitroreductase
FY131_06130	COG0823	Involved in the tonB-independent uptake of proteins
FY131_06145	COG1368	sulfuric ester hydrolase activity
FY131_06175	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY131_06195	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY131_06215	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY131_06240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY131_06240	COG0512	Glutamine amidotransferase of anthranilate synthase
FY131_06245	COG0343	queuine tRNA-ribosyltransferase activity
FY131_06250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY131_06265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY131_06280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY131_06285	COG0134	indole-3-glycerol-phosphate synthase activity
FY131_06290	COG0315	cyclic pyranopterin monophosphate synthase activity
FY131_06295	COG0303	'Molybdopterin
FY131_06300	COG3706	GGDEF domain
FY131_06310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY131_06310	COG0475	glutathione-regulated potassium exporter activity
FY131_06320	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY131_06325	COG0697	spore germination
FY131_06330	COG2814	Major facilitator Superfamily
FY131_06335	COG0746	molybdenum cofactor guanylyltransferase activity
FY131_06340	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY131_06345	COG0739	heme binding
FY131_06350	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY131_06355	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY131_06360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY131_06365	COG0805	protein transport
FY131_06370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY131_06375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY131_06380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY131_06385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY131_06390	COG1472	Belongs to the glycosyl hydrolase 3 family
FY131_06400	COG0018	arginyl-trna synthetase
FY131_06405	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY131_06410	COG0316	Belongs to the HesB IscA family
FY131_06435	COG0525	valine-tRNA ligase activity
FY131_06445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY131_06470	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY131_06475	COG1058	Belongs to the CinA family
FY131_06475	COG1546	Belongs to the CinA family
FY131_06480	COG0589	response to stress
FY131_06485	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY131_06495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY131_06510	COG1914	H( )-stimulated, divalent metal cation uptake system
FY131_06520	COG1132	(ABC) transporter
FY131_06525	COG0628	permease
FY131_06560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY131_06570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY131_06580	COG0302	gtp cyclohydrolase
FY131_06585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY131_06590	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY131_06595	COG0516	GMP reductase activity
FY131_06595	COG0517	IMP dehydrogenase activity
FY131_06625	COG1760	l-serine dehydratase
FY131_06660	COG0583	DNA-binding transcription factor activity
FY131_06675	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY131_06675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY131_06680	COG0347	Belongs to the P(II) protein family
FY131_06685	COG0174	glutamine synthetase
FY131_06715	COG0697	spore germination
FY131_06725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY131_06735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY131_06765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY131_06770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY131_06775	COG2186	Transcriptional regulator
FY131_06785	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY131_06790	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY131_06795	COG3845	ABC transporter
FY131_06800	COG1183	phosphatidylcholine synthase activity
FY131_06805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY131_06810	COG0679	Auxin Efflux Carrier
FY131_06815	COG0785	Cytochrome C biogenesis protein
FY131_06845	COG0346	lactoylglutathione lyase activity
FY131_06850	COG1278	Cold shock
FY131_06900	COG0577	efflux transmembrane transporter activity
FY131_06900	COG1136	(ABC) transporter
FY131_06905	COG0577	efflux transmembrane transporter activity
FY131_06905	COG1136	(ABC) transporter
FY131_06920	COG2151	metal-sulfur cluster biosynthetic enzyme
FY131_06925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY131_06930	COG0719	Fe-S assembly protein
FY131_06935	COG0396	ATPase activity
FY131_06940	COG0719	Fe-S assembly protein
FY131_06945	COG1104	cysteine desulfurase activity
FY131_06950	COG2945	thiolester hydrolase activity
FY131_06955	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY131_06960	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY131_06970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY131_06975	COG2833	Protein of unknown function (DUF455)
FY131_06980	COG0739	heme binding
FY131_06985	COG0513	Belongs to the DEAD box helicase family
FY131_07010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY131_07020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY131_07025	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY131_07030	COG0047	phosphoribosylformylglycinamidine synthase activity
FY131_07045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY131_07055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY131_07075	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY131_07080	COG2814	Major facilitator Superfamily
FY131_07085	COG0483	inositol monophosphate 1-phosphatase activity
FY131_07090	COG0483	inositol monophosphate 1-phosphatase activity
FY131_07095	COG0037	tRNA processing
FY131_07100	COG2066	Belongs to the glutaminase family
FY131_07105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY131_07110	COG0861	Integral membrane protein TerC family
FY131_07130	COG1280	lysine exporter protein (LysE YggA)
FY131_07140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY131_07145	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY131_07155	COG0538	isocitrate dehydrogenase activity
FY131_07170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY131_07175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY131_07180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_07185	COG2313	pseudouridylate synthase activity
FY131_07195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_07200	COG4215	(ABC) transporter
FY131_07210	COG5425	PFAM Usg family protein
FY131_07220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY131_07225	COG1522	sequence-specific DNA binding
FY131_07230	COG1573	uracil-dna glycosylase
FY131_07240	COG2202	Pas domain
FY131_07240	COG2205	protein histidine kinase activity
FY131_07250	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY131_07255	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY131_07270	COG0842	Transport permease protein
FY131_07275	COG1131	(ABC) transporter
FY131_07280	COG0730	response to heat
FY131_07290	COG0840	transmembrane signaling receptor activity
FY131_07290	COG0840	transmembrane signaling receptor activity
FY131_07300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY131_07305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY131_07320	COG0129	dihydroxy-acid dehydratase activity
FY131_07325	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY131_07330	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY131_07340	COG3739	integral membrane protein
FY131_07350	COG0203	ribosomal protein L17
FY131_07355	COG0202	RNA polymerase activity
FY131_07360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY131_07365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY131_07370	COG0563	adenylate kinase activity
FY131_07375	COG0201	protein transport
FY131_07380	COG0200	Binds to the 23S rRNA
FY131_07385	COG1841	ribosomal large subunit assembly
FY131_07390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY131_07395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY131_07400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY131_07405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY131_07410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY131_07415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY131_07420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY131_07425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY131_07430	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY131_07435	COG0255	Belongs to the universal ribosomal protein uL29 family
FY131_07440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY131_07445	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY131_07450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY131_07455	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY131_07460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY131_07465	COG0089	rRNA binding
FY131_07470	COG0088	Forms part of the polypeptide exit tunnel
FY131_07475	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY131_07480	COG0051	transcription antitermination factor activity, RNA binding
FY131_07485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY131_07490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY131_07495	COG0049	tRNA binding
FY131_07500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY131_07515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY131_07520	COG0085	RNA polymerase activity
FY131_07530	COG0222	ribosome binding
FY131_07535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY131_07540	COG0081	regulation of translation
FY131_07545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY131_07555	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY131_07570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY131_07575	COG0861	Integral membrane protein TerC family
FY131_07605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY131_07610	COG1607	acyl-coa hydrolase
FY131_07635	COG2910	NAD(P)H-binding
FY131_07640	COG1733	regulation of RNA biosynthetic process
FY131_07650	COG0556	nucleotide-excision repair
FY131_07655	COG2382	esterase
FY131_07675	COG0484	heat shock protein binding
FY131_07685	COG0582	viral genome integration into host DNA
FY131_07800	COG3842	ATPase activity
FY131_07810	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY131_07830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY131_07840	COG2207	Transcriptional regulator
FY131_07845	COG1064	alcohol dehydrogenase
FY131_07850	COG1252	NADH dehydrogenase
FY131_07855	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY131_07860	COG2197	response regulator
FY131_07865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY131_07870	COG1090	epimerase
FY131_07910	COG0656	L-ascorbic acid biosynthetic process
FY131_07925	COG0440	acetolactate synthase activity
FY131_07930	COG0028	Belongs to the TPP enzyme family
FY131_07940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY131_07945	COG0560	Phosphoserine phosphatase
FY131_07945	COG3830	Belongs to the UPF0237 family
FY131_07965	COG0330	HflC and HflK could
FY131_07970	COG0330	HflC and HflK could
FY131_07980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY131_08020	COG0277	FAD linked oxidase domain protein
FY131_08025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY131_08080	COG1335	isochorismatase
FY131_08100	COG0006	proline dipeptidase activity
FY131_08105	COG2264	protein methyltransferase activity
FY131_08110	COG1999	signal sequence binding
FY131_08120	COG0835	chemotaxis
FY131_08130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY131_08135	COG0583	DNA-binding transcription factor activity
FY131_08145	COG1247	-acetyltransferase
FY131_08155	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY131_08170	COG0497	DNA recombination
FY131_08175	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY131_08185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY131_08190	COG0849	cell division
FY131_08195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY131_08200	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY131_08205	COG0477	Major facilitator Superfamily
FY131_08215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY131_08220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY131_08225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY131_08235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY131_08240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY131_08250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY131_08265	COG0275	rRNA processing
FY131_08270	COG2001	Belongs to the MraZ family
FY131_08295	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY131_08325	COG4106	trans-aconitate 2-methyltransferase activity
FY131_08345	COG2226	methyltransferase
FY131_08355	COG2267	carboxylic ester hydrolase activity
FY131_08360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY131_08375	COG0251	oxidation-reduction process
FY131_08390	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_08395	COG2814	Major facilitator Superfamily
FY131_08420	COG1012	belongs to the aldehyde dehydrogenase family
FY131_08425	COG0174	glutamine synthetase
FY131_08430	COG0531	amino acid
FY131_08440	COG1737	Transcriptional regulator
FY131_08445	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_08460	COG3842	ATPase activity
FY131_08520	COG2968	Membrane
FY131_08530	COG0432	Pfam Uncharacterised protein family UPF0047
FY131_08545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY131_08550	COG0358	DNA primase activity
FY131_08560	COG0505	Belongs to the CarA family
FY131_08565	COG0534	Mate efflux family protein
FY131_08580	COG2321	neutral zinc metallopeptidase
FY131_08595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY131_08600	COG3706	GGDEF domain
FY131_08605	COG1573	uracil-dna glycosylase
FY131_08615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY131_08625	COG1522	sequence-specific DNA binding
FY131_08630	COG0492	ferredoxin-NADP+ reductase activity
FY131_08635	COG0583	DNA-binding transcription factor activity
FY131_08645	COG1902	pentaerythritol trinitrate reductase activity
FY131_08670	COG0387	Pfam Sodium calcium exchanger
FY131_08675	COG0436	Aminotransferase
FY131_08680	COG2199	diguanylate cyclase activity
FY131_08680	COG2200	EAL domain
FY131_08695	COG1278	Cold shock
FY131_08700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY131_08710	COG1846	Transcriptional regulator
FY131_08715	COG0745	RESPONSE REGULATOR receiver
FY131_08720	COG2205	protein histidine kinase activity
FY131_08725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY131_08745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY131_08755	COG1496	oxidoreductase activity
FY131_08770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY131_08780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY131_08795	COG0840	transmembrane signaling receptor activity
FY131_08800	COG1012	belongs to the aldehyde dehydrogenase family
FY131_08810	COG3300	MHYT domain
FY131_08810	COG5001	Diguanylate cyclase
FY131_08815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY131_08820	COG5001	Diguanylate cyclase
FY131_08830	COG0193	aminoacyl-tRNA hydrolase activity
FY131_08840	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY131_08860	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY131_08865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY131_08875	COG2857	Cytochrome c1
FY131_08875	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY131_08895	COG1132	(ABC) transporter
FY131_08900	COG1132	(ABC) transporter
FY131_08905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY131_08920	COG0408	coproporphyrinogen oxidase activity
FY131_08935	COG0617	tRNA 3'-terminal CCA addition
FY131_08950	COG0714	Associated with various cellular activities
FY131_08970	COG0454	-acetyltransferase
FY131_08975	COG0477	Major facilitator Superfamily
FY131_08985	COG0435	Glutathione S-transferase
FY131_09000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY131_09005	COG3135	benzoate transporter
FY131_09010	COG4944	Protein of unknown function (DUF1109)
FY131_09025	COG0740	serine-type endopeptidase activity
FY131_09040	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY131_09045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY131_09075	COG4175	Glycine betaine
FY131_09090	COG1435	thymidine kinase activity
FY131_09110	COG2862	Uncharacterized protein family, UPF0114
FY131_09125	COG0512	Glutamine amidotransferase of anthranilate synthase
FY131_09125	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY131_09135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY131_09145	COG0366	Alpha amylase catalytic
FY131_09150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_09165	COG1160	GTP binding
FY131_09185	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY131_09195	COG0024	Methionine aminopeptidase
FY131_09210	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_09220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY131_09230	COG0583	DNA-binding transcription factor activity
FY131_09245	COG0402	S-adenosylhomocysteine deaminase activity
FY131_09270	COG1309	transcriptional regulator
FY131_09275	COG1686	Belongs to the peptidase S11 family
FY131_09285	COG2351	hydroxyisourate hydrolase activity
FY131_09290	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY131_09315	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY131_09325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_09325	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY131_09330	COG5002	protein histidine kinase activity
FY131_09330	COG2205	protein histidine kinase activity
FY131_09330	COG0784	Response regulator, receiver
FY131_09335	COG0513	Belongs to the DEAD box helicase family
FY131_09345	COG2259	Doxx family
FY131_09350	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_09360	COG2308	Evidence 4 Homologs of previously reported genes of
FY131_09370	COG1305	Transglutaminase-like
FY131_09400	COG4214	carbohydrate transport
FY131_09405	COG1129	ABC transporter
FY131_09410	COG4213	ABC transporter substrate-binding protein
FY131_09445	COG0840	transmembrane signaling receptor activity
FY131_09465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_09495	COG1215	transferase activity, transferring glycosyl groups
FY131_09510	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FY131_09525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY131_09530	COG2346	COG2346, Truncated hemoglobins
FY131_09550	COG1309	transcriptional regulator
FY131_09565	COG0494	nUDIX hydrolase
FY131_09575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_09580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_09610	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY131_09615	COG0830	nickel cation binding
FY131_09620	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY131_09635	COG0804	urea catabolic process
FY131_09640	COG1442	glycosyl transferase family 8
FY131_09645	COG3755	Protein conserved in bacteria
FY131_09655	COG0832	Belongs to the urease beta subunit family
FY131_09660	COG3813	Protein conserved in bacteria
FY131_09665	COG0831	urea catabolic process
FY131_09670	COG0829	nickel cation binding
FY131_09695	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY131_09710	COG0174	glutamine synthetase
FY131_09715	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_09720	COG2198	Histidine kinase
FY131_09720	COG5002	protein histidine kinase activity
FY131_09720	COG0784	Response regulator, receiver
FY131_09765	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY131_09840	COG0564	pseudouridine synthase activity
FY131_09855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY131_09865	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY131_09890	COG0346	lactoylglutathione lyase activity
FY131_09900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY131_09910	COG2832	Protein of unknown function (DUF454)
FY131_09915	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY131_09920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_09925	COG4558	Periplasmic binding protein
FY131_09935	COG3721	Heme iron utilization protein
FY131_09955	COG2205	protein histidine kinase activity
FY131_09995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_10000	COG4605	iron ion homeostasis
FY131_10005	COG4604	ABC transporter, ATP-binding protein
FY131_10010	COG0783	Belongs to the Dps family
FY131_10025	COG0840	transmembrane signaling receptor activity
FY131_10025	COG2972	Histidine kinase
FY131_10035	COG2814	Major facilitator Superfamily
FY131_10045	COG0583	DNA-binding transcription factor activity
FY131_10050	COG0657	acetylesterase activity
FY131_10055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_10075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY131_10080	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY131_10085	COG0288	reversible hydration of carbon dioxide
FY131_10095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY131_10115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY131_10120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY131_10125	COG0778	Nitroreductase
FY131_10130	COG2267	carboxylic ester hydrolase activity
FY131_10135	COG0251	oxidation-reduction process
FY131_10140	COG1335	isochorismatase
FY131_10145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_10155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_10170	COG1175	transmembrane transport
FY131_10175	COG0395	ABC-type sugar transport system, permease component
FY131_10180	COG3842	ATPase activity
FY131_10185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_10195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY131_10210	COG4608	Belongs to the ABC transporter superfamily
FY131_10215	COG0444	Belongs to the ABC transporter superfamily
FY131_10220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_10225	COG0601	transmembrane transport
FY131_10245	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FY131_10245	COG0392	lysyltransferase activity
FY131_10285	COG2159	amidohydrolase
FY131_10290	COG1960	acyl-CoA dehydrogenase activity
FY131_10315	COG0745	RESPONSE REGULATOR receiver
FY131_10325	COG1902	pentaerythritol trinitrate reductase activity
FY131_10325	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY131_10330	COG3842	ATPase activity
FY131_10340	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_10345	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_10350	COG0745	RESPONSE REGULATOR receiver
FY131_10365	COG1192	Involved in chromosome partitioning
FY131_10370	COG2201	protein-glutamate methylesterase activity
FY131_10375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY131_10380	COG0835	chemotaxis
FY131_10385	COG0840	transmembrane signaling receptor activity
FY131_10390	COG0835	chemotaxis
FY131_10395	COG0643	Histidine kinase
FY131_10395	COG2198	Histidine kinase
FY131_10460	COG0277	FAD linked oxidase domain protein
FY131_10470	COG1017	nitric oxide dioxygenase activity
FY131_10470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY131_10505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY131_10515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_10520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY131_10530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY131_10555	COG0583	DNA-binding transcription factor activity
FY131_10560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_10565	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY131_10570	COG4149	molybdate abc transporter
FY131_10575	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY131_10590	COG2022	thiamine diphosphate biosynthetic process
FY131_10605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY131_10610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY131_10620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY131_10640	COG1132	(ABC) transporter
FY131_10645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY131_10670	COG0438	transferase activity, transferring glycosyl groups
FY131_10690	COG4166	transmembrane transport
FY131_10695	COG0601	transmembrane transport
FY131_10700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_10710	COG0438	transferase activity, transferring glycosyl groups
FY131_10715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY131_10720	COG3142	Participates in the control of copper homeostasis
FY131_10725	COG2814	Major facilitator Superfamily
FY131_10740	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_10745	COG1737	Transcriptional regulator
FY131_10755	COG3842	ATPase activity
FY131_10765	COG0395	ABC-type sugar transport system, permease component
FY131_10780	COG2188	Transcriptional regulator
FY131_10785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY131_10790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY131_10795	COG1940	carbohydrate kinase activity
FY131_10805	COG0671	phosphoesterase, PA-phosphatase related
FY131_10810	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY131_10815	COG0156	8-amino-7-oxononanoate synthase activity
FY131_10825	COG0729	surface antigen
FY131_10835	COG0835	chemotaxis
FY131_10845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY131_10850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY131_10855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY131_10860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY131_10865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY131_10870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY131_10885	COG4974	Belongs to the 'phage' integrase family
FY131_10910	COG1280	lysine exporter protein (LysE YggA)
FY131_10920	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY131_10925	COG0567	Dehydrogenase, E1 component
FY131_10930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY131_10935	COG0045	succinate-CoA ligase (ADP-forming) activity
FY131_10940	COG0039	L-malate dehydrogenase activity
FY131_10945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY131_10980	COG2264	protein methyltransferase activity
FY131_10995	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY131_11000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY131_11005	COG0181	hydroxymethylbilane synthase activity
FY131_11045	COG1872	DUF167
FY131_11050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY131_11060	COG1217	gtp-binding protein TYPA
FY131_11065	COG0339	signal peptide processing
FY131_11075	COG1846	Transcriptional regulator
FY131_11085	COG0137	argininosuccinate synthase activity
FY131_11095	COG1280	lysine exporter protein (LysE YggA)
FY131_11100	COG1122	ATPase activity
FY131_11105	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY131_11115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY131_11130	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY131_11135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY131_11140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY131_11150	COG4181	ATPase activity
FY131_11160	COG0670	Belongs to the BI1 family
FY131_11175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY131_11180	COG4133	protoheme IX ABC transporter activity
FY131_11185	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY131_11190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY131_11215	COG2917	probably involved in intracellular septation
FY131_11220	COG0552	protein localization to endoplasmic reticulum
FY131_11225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY131_11230	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY131_11240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY131_11245	COG1605	Chorismate mutase
FY131_11245	COG0287	Prephenate dehydrogenase
FY131_11250	COG0228	four-way junction DNA binding
FY131_11255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY131_11260	COG0336	Belongs to the RNA methyltransferase TrmD family
FY131_11270	COG0335	large ribosomal subunit rRNA binding
FY131_11275	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY131_11280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_11295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY131_11305	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY131_11325	COG0488	(ABC) transporter
FY131_11335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY131_11345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY131_11350	COG0142	geranyltranstransferase activity
FY131_11355	COG2885	chlorophyll binding
FY131_11360	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY131_11365	COG2223	nitrite transmembrane transporter activity
FY131_11370	COG1349	DNA-binding transcription factor activity
FY131_11375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY131_11380	COG2197	response regulator
FY131_11385	COG1132	(ABC) transporter
FY131_11390	COG3459	Glycosyltransferase 36 associated
FY131_11395	COG1473	amidohydrolase
FY131_11400	COG0579	oxidoreductase
FY131_11410	COG0129	dihydroxy-acid dehydratase activity
FY131_11415	COG2084	Dehydrogenase
FY131_11420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_11425	COG0277	FAD linked oxidase domain protein
FY131_11430	COG2186	Transcriptional regulator
FY131_11440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY131_11445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY131_11450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY131_11455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY131_11470	COG0495	leucyl-tRNA aminoacylation
FY131_11485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY131_11490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY131_11500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY131_11505	COG1946	Acyl-CoA thioesterase
FY131_11510	COG0347	Belongs to the P(II) protein family
FY131_11515	COG0004	ammonium transporteR
FY131_11520	COG1674	ftsk spoiiie
FY131_11525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY131_11540	COG0745	RESPONSE REGULATOR receiver
FY131_11550	COG1329	Transcriptional regulator
FY131_11555	COG2902	Dehydrogenase
FY131_11560	COG2270	Major facilitator Superfamily
FY131_11575	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_11590	COG0494	nUDIX hydrolase
FY131_11600	COG0793	Belongs to the peptidase S41A family
FY131_11610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY131_11615	COG0799	negative regulation of ribosome biogenesis
FY131_11620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY131_11625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY131_11630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY131_11635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY131_11650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY131_11655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY131_11680	COG0066	3-isopropylmalate dehydratase activity
FY131_11685	COG0473	3-isopropylmalate dehydrogenase activity
FY131_11690	COG1858	cytochrome C peroxidase
FY131_11695	COG1797	cobyrinic acid a,c-diamide synthase activity
FY131_11700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY131_11700	COG1648	precorrin-2 dehydrogenase activity
FY131_11705	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY131_11770	COG1492	cobalamin metabolic process
FY131_11785	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_11790	COG3254	rhamnose metabolic process
FY131_11795	COG0246	Mannitol dehydrogenase
FY131_11800	COG1063	alcohol dehydrogenase
FY131_11820	COG4214	carbohydrate transport
FY131_11825	COG1129	ABC transporter
FY131_11830	COG2186	Transcriptional regulator
FY131_11835	COG2721	sulfolactate sulfo-lyase activity
FY131_11840	COG0138	bifunctional purine biosynthesis protein purh
FY131_11850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY131_11850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY131_11855	COG0501	Belongs to the peptidase M48B family
FY131_11875	COG0357	Ribosomal RNA small subunit methyltransferase G
FY131_11880	COG0445	tRNA wobble uridine modification
FY131_11885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY131_11890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY131_11895	COG1981	membrane
FY131_11900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY131_11905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY131_11910	COG0424	maF-like protein
FY131_11915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY131_11920	COG0237	dephospho-CoA kinase activity
FY131_11930	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY131_11945	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY131_11970	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY131_11985	COG0135	phosphoribosylanthranilate isomerase activity
FY131_11990	COG0133	tryptophan synthase activity
FY131_11995	COG0159	tryptophan synthase activity
FY131_12000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY131_12015	COG1074	ATP-dependent DNA helicase activity
FY131_12025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY131_12030	COG0802	atpase or kinase
FY131_12035	COG2205	protein histidine kinase activity
FY131_12040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY131_12045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY131_12050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY131_12050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY131_12055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY131_12060	COG0642	Histidine kinase
FY131_12065	COG0745	RESPONSE REGULATOR receiver
FY131_12070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY131_12080	COG1652	LysM domain
FY131_12085	COG1072	(Pantothenic acid kinase))
FY131_12090	COG0140	phosphoribosyl-ATP diphosphatase activity
FY131_12095	COG0107	imidazoleglycerol-phosphate synthase activity
FY131_12100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY131_12105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY131_12115	COG0131	Imidazoleglycerol-phosphate dehydratase
FY131_12120	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY131_12125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY131_12135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY131_12150	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY131_12160	COG1643	Atp-dependent helicase
FY131_12220	COG1072	(Pantothenic acid kinase))
FY131_12230	COG1780	Probably involved in ribonucleotide reductase function
FY131_12250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY131_12275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_12290	COG1185	polyribonucleotide nucleotidyltransferase activity
FY131_12295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY131_12300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY131_12305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY131_12310	COG3064	Membrane
FY131_12310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY131_12325	COG0779	Required for maturation of 30S ribosomal subunits
FY131_12330	COG2814	Major facilitator Superfamily
FY131_12335	COG2951	lytic endotransglycosylase activity
FY131_12340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY131_12350	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY131_12355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY131_12370	COG2816	NAD+ diphosphatase activity
FY131_12375	COG1605	Chorismate mutase
FY131_12375	COG0077	Prephenate dehydratase
FY131_12380	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY131_12385	COG3474	cytochrome
FY131_12395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY131_12400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY131_12405	COG1278	Cold shock
FY131_12410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY131_12420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY131_12420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY131_12430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY131_12460	COG2900	Belongs to the SlyX family
FY131_12470	COG0484	heat shock protein binding
FY131_12475	COG0443	Heat shock 70 kDa protein
FY131_12490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY131_12495	COG1744	ABC transporter substrate-binding protein PnrA-like
FY131_12500	COG3845	ABC transporter
FY131_12505	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY131_12510	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY131_12515	COG0295	cytidine deaminase activity
FY131_12525	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY131_12530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY131_12540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY131_12545	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY131_12550	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY131_12565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY131_12570	COG1845	cytochrome c oxidase, subunit III
FY131_12575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY131_12580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY131_12585	COG0477	Major facilitator Superfamily
FY131_12595	COG0067	glutamate synthase
FY131_12595	COG0069	glutamate synthase activity
FY131_12595	COG0070	glutamate synthase
FY131_12600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY131_12615	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY131_12625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY131_12665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_12685	COG0848	biopolymer transport protein
FY131_12695	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY131_12710	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY131_12715	COG3454	Phosphonate metabolism
FY131_12720	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY131_12725	COG3639	organic phosphonate transmembrane transporter activity
FY131_12730	COG3639	organic phosphonate transmembrane transporter activity
FY131_12740	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY131_12750	COG4778	phosphonate C-P lyase system protein PhnL
FY131_12755	COG4107	phosphonate C-P lyase system protein PhnK
FY131_12760	COG3627	carbon phosphorus lyase activity
FY131_12765	COG3626	phosphonate metabolism
FY131_12770	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY131_12775	COG3624	Phosphonate C-P lyase system protein PhnG
FY131_12780	COG2188	Transcriptional regulator
FY131_12785	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY131_12790	COG0837	glucose binding
FY131_12795	COG1803	Methylglyoxal synthase
FY131_12800	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY131_12805	COG4166	transmembrane transport
FY131_12810	COG4174	ABC transporter (Permease)
FY131_12815	COG4239	(ABC) transporter, permease
FY131_12820	COG4172	Belongs to the ABC transporter superfamily
FY131_12825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_12830	COG0174	glutamine synthetase
FY131_12835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_12840	COG3265	gluconokinase activity
FY131_12845	COG1174	glycine betaine transport
FY131_12850	COG1125	glycine betaine transport
FY131_12855	COG1174	glycine betaine transport
FY131_12860	COG1732	Glycine betaine
FY131_12870	COG1959	2 iron, 2 sulfur cluster binding
FY131_12875	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_12895	COG0697	spore germination
FY131_12910	COG0791	NLP P60 protein
FY131_12920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY131_12925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY131_12960	COG4964	Belongs to the GSP D family
FY131_13000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY131_13005	COG3422	double-strand break repair
FY131_13010	COG3757	hydrolase, family 25
FY131_13015	COG0697	spore germination
FY131_13020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY131_13050	COG0481	GTPase activity
FY131_13055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY131_13085	COG1917	Cupin 2, conserved barrel domain protein
FY131_13085	COG2169	Transcriptional regulator
FY131_13090	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY131_13115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY131_13120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY131_13125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY131_13135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY131_13140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY131_13140	COG0072	phenylalanine-tRNA ligase activity
FY131_13145	COG0667	Aldo Keto reductase
FY131_13165	COG4977	sequence-specific DNA binding
FY131_13190	COG1570	exodeoxyribonuclease VII activity
FY131_13195	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_13205	COG1846	Transcriptional regulator
FY131_13210	COG0697	spore germination
FY131_13215	COG2309	aminopeptidase activity
FY131_13225	COG1393	Belongs to the ArsC family
FY131_13235	COG0519	Catalyzes the synthesis of GMP from XMP
FY131_13235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY131_13250	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY131_13280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY131_13290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY131_13300	COG1968	undecaprenyl-diphosphatase activity
FY131_13315	COG0284	orotidine-5'-phosphate decarboxylase activity
FY131_13325	COG3963	phosphatidate phosphatase activity
FY131_13335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY131_13340	COG0792	nuclease activity
FY131_13355	COG1175	transmembrane transport
FY131_13360	COG0395	ABC-type sugar transport system, permease component
FY131_13365	COG3842	ATPase activity
FY131_13375	COG0189	ligase activity
FY131_13385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY131_13390	COG1280	lysine exporter protein (LysE YggA)
FY131_13395	COG0756	dUTP diphosphatase activity
FY131_13400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY131_13405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY131_13420	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY131_13425	COG2226	methyltransferase
FY131_13430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY131_13435	COG1024	Enoyl-CoA hydratase
FY131_13440	COG0268	Binds directly to 16S ribosomal RNA
FY131_13480	COG0406	alpha-ribazole phosphatase activity
FY131_13555	COG0297	glycogen (starch) synthase activity
FY131_13560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY131_13595	COG3685	Protein conserved in bacteria
FY131_13600	COG0753	catalase activity
FY131_13630	COG2433	Pfam Transposase IS66
FY131_13650	COG2197	response regulator
FY131_13665	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY131_13675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_13700	COG3436	PFAM IS66 Orf2 family protein
FY131_13955	COG1522	sequence-specific DNA binding
FY131_13965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY131_13970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY131_13975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY131_13980	COG2423	ornithine cyclodeaminase activity
FY131_13985	COG0006	proline dipeptidase activity
FY131_13990	COG3608	succinylglutamate desuccinylase aspartoacylase
FY131_13995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_14000	COG0765	amino acid transport
FY131_14005	COG0765	amino acid transport
FY131_14010	COG1126	abc transporter atp-binding protein
FY131_14030	COG1309	transcriptional regulator
FY131_14035	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_14045	COG1595	DNA-templated transcription, initiation
FY131_14055	COG3012	SEC-C Motif Domain Protein
FY131_14060	COG4372	Transposase
FY131_14065	COG3436	PFAM IS66 Orf2 family protein
FY131_14085	COG0529	Catalyzes the synthesis of activated sulfate
FY131_14085	COG2895	sulfate adenylyltransferase (ATP) activity
FY131_14090	COG0175	sulfate reduction
FY131_14110	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY131_14130	COG2433	Pfam Transposase IS66
FY131_14175	COG1216	Glycosyl transferase, family 2
FY131_14175	COG0438	transferase activity, transferring glycosyl groups
FY131_14185	COG1368	sulfuric ester hydrolase activity
FY131_14190	COG0300	oxidoreductase activity
FY131_14195	COG0156	8-amino-7-oxononanoate synthase activity
FY131_14200	COG0604	alcohol dehydrogenase
FY131_14200	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_14200	COG3321	synthase
FY131_14215	COG0372	Belongs to the citrate synthase family
FY131_14220	COG0372	Belongs to the citrate synthase family
FY131_14255	COG3046	protein related to deoxyribodipyrimidine photolyase
FY131_14260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY131_14275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY131_14295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY131_14340	COG0753	catalase activity
FY131_14350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FY131_14360	COG0640	Transcriptional regulator
FY131_14365	COG5265	(ABC) transporter
FY131_14375	COG3181	Tripartite tricarboxylate transporter family receptor
FY131_14380	COG2197	response regulator
FY131_14385	COG3237	CsbD-like
FY131_14415	COG0456	acetyltransferase
FY131_14420	COG2223	nitrite transmembrane transporter activity
FY131_14430	COG3383	formate dehydrogenase (NAD+) activity
FY131_14455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY131_14460	COG1802	Transcriptional regulator
FY131_14465	COG4608	Belongs to the ABC transporter superfamily
FY131_14470	COG0444	Belongs to the ABC transporter superfamily
FY131_14475	COG0402	S-adenosylhomocysteine deaminase activity
FY131_14485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_14490	COG0601	transmembrane transport
FY131_14500	COG0402	S-adenosylhomocysteine deaminase activity
FY131_14515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY131_14525	COG0765	amino acid transport
FY131_14530	COG0765	amino acid transport
FY131_14535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_14550	COG3938	Belongs to the proline racemase family
FY131_14560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_14570	COG0765	amino acid transport
FY131_14585	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY131_14590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_14600	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY131_14605	COG0784	Response regulator, receiver
FY131_14620	COG0842	Transport permease protein
FY131_14625	COG1129	ABC transporter
FY131_14625	COG0842	Transport permease protein
FY131_14630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_14635	COG1486	melibiose metabolic process
FY131_14640	COG4172	Belongs to the ABC transporter superfamily
FY131_14645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_14650	COG0601	transmembrane transport
FY131_14655	COG0747	negative chemotaxis
FY131_14660	COG1486	melibiose metabolic process
FY131_14685	COG1940	carbohydrate kinase activity
FY131_14690	COG2182	Extracellular solute-binding protein
FY131_14695	COG1175	transmembrane transport
FY131_14700	COG0395	ABC-type sugar transport system, permease component
FY131_14705	COG0165	Argininosuccinate lyase
FY131_14710	COG3842	ATPase activity
FY131_14715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_14720	COG3119	arylsulfatase activity
FY131_14730	COG0583	DNA-binding transcription factor activity
FY131_14735	COG1012	belongs to the aldehyde dehydrogenase family
FY131_14760	COG1733	regulation of RNA biosynthetic process
FY131_14765	COG1120	ATPase activity
FY131_14770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_14775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_14785	COG4774	siderophore transport
FY131_14795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY131_14810	COG5002	protein histidine kinase activity
FY131_14815	COG0745	RESPONSE REGULATOR receiver
FY131_14845	COG1392	Phosphate transport regulator
FY131_14850	COG0306	phosphate transporter
FY131_14855	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY131_14865	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY131_14875	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_14880	COG5001	Diguanylate cyclase
FY131_14880	COG3300	MHYT domain
FY131_14890	COG0747	negative chemotaxis
FY131_14900	COG2186	Transcriptional regulator
FY131_14905	COG0601	transmembrane transport
FY131_14910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_14915	COG0444	Belongs to the ABC transporter superfamily
FY131_14920	COG4608	Belongs to the ABC transporter superfamily
FY131_14925	COG3842	ATPase activity
FY131_14930	COG0395	ABC-type sugar transport system, permease component
FY131_14945	COG1233	COG1233 Phytoene dehydrogenase and related
FY131_14950	COG1609	Transcriptional regulator
FY131_14965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY131_14970	COG4774	siderophore transport
FY131_14975	COG1120	ATPase activity
FY131_14980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_14985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_14990	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY131_15000	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY131_15005	COG1088	dTDP-glucose 4,6-dehydratase activity
FY131_15010	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY131_15015	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY131_15030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY131_15035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY131_15045	COG1132	(ABC) transporter
FY131_15050	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY131_15060	COG0385	Bile acid
FY131_15080	COG1177	transmembrane transport
FY131_15085	COG3842	ATPase activity
FY131_15100	COG0483	inositol monophosphate 1-phosphatase activity
FY131_15105	COG0584	glycerophosphoryl diester phosphodiesterase
FY131_15115	COG4149	molybdate abc transporter
FY131_15120	COG3842	ATPase activity
FY131_15150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY131_15160	COG3842	ATPase activity
FY131_15165	COG1175	transmembrane transport
FY131_15170	COG0395	ABC-type sugar transport system, permease component
FY131_15175	COG1609	Transcriptional regulator
FY131_15185	COG0673	inositol 2-dehydrogenase activity
FY131_15190	COG1082	Xylose isomerase domain protein TIM barrel
FY131_15200	COG1609	Transcriptional regulator
FY131_15205	COG0183	Belongs to the thiolase family
FY131_15210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY131_15220	COG1414	Transcriptional regulator
FY131_15235	COG0583	DNA-binding transcription factor activity
FY131_15245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY131_15250	COG3485	protocatechuate 3,4-dioxygenase
FY131_15255	COG3485	protocatechuate 3,4-dioxygenase
FY131_15265	COG0765	amino acid transport
FY131_15270	COG0765	amino acid transport
FY131_15275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_15280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_15285	COG1126	abc transporter atp-binding protein
FY131_15290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY131_15295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY131_15305	COG1082	Xylose isomerase domain protein TIM barrel
FY131_15305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FY131_15320	COG0747	negative chemotaxis
FY131_15330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_15345	COG0683	leucine binding
FY131_15365	COG3842	ATPase activity
FY131_15375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_15380	COG3962	Belongs to the TPP enzyme family
FY131_15390	COG3718	enzyme involved in inositol metabolism
FY131_15395	COG0673	inositol 2-dehydrogenase activity
FY131_15400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY131_15405	COG1609	Transcriptional regulator
FY131_15410	COG1846	Transcriptional regulator
FY131_15420	COG0523	cobalamin synthesis protein
FY131_15455	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY131_15475	COG0800	Aldolase
FY131_15480	COG2954	triphosphatase activity
FY131_15490	COG1054	Belongs to the UPF0176 family
FY131_15495	COG3300	MHYT domain
FY131_15495	COG5001	Diguanylate cyclase
FY131_15505	COG2011	ABC-type metal ion transport system permease component
FY131_15510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY131_15515	COG0778	Nitroreductase
FY131_15525	COG2115	Belongs to the xylose isomerase family
FY131_15530	COG1070	Carbohydrate kinase
FY131_15535	COG1609	Transcriptional regulator
FY131_15550	COG1309	transcriptional regulator
FY131_15555	COG1253	flavin adenine dinucleotide binding
FY131_15560	COG3273	potassium ion transport
FY131_15560	COG0471	metal ion transport
FY131_15565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY131_15570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY131_15580	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY131_15585	COG1121	(ABC) transporter
FY131_15590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY131_15595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY131_15600	COG5487	UPF0391 membrane protein
FY131_15605	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_15610	COG1414	Transcriptional regulator
FY131_15615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY131_15625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY131_15650	COG1069	ribulokinase activity
FY131_15670	COG0395	ABC-type sugar transport system, permease component
FY131_15675	COG1175	transmembrane transport
FY131_15685	COG2390	Transcriptional regulator
FY131_15690	COG4172	Belongs to the ABC transporter superfamily
FY131_15695	COG1473	amidohydrolase
FY131_15705	COG0601	transmembrane transport
FY131_15710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_15720	COG0693	protein deglycase activity
FY131_15725	COG0154	amidase activity
FY131_15730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_15740	COG0747	negative chemotaxis
FY131_15745	COG0583	DNA-binding transcription factor activity
FY131_15750	COG4608	Belongs to the ABC transporter superfamily
FY131_15755	COG0444	Belongs to the ABC transporter superfamily
FY131_15760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_15765	COG0601	transmembrane transport
FY131_15770	COG0747	negative chemotaxis
FY131_15780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY131_15785	COG1473	amidohydrolase
FY131_15795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY131_15815	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY131_15825	COG1609	Transcriptional regulator
FY131_15830	COG0583	DNA-binding transcription factor activity
FY131_15835	COG1960	acyl-CoA dehydrogenase activity
FY131_15840	COG4774	siderophore transport
FY131_15840	COG1629	transport
FY131_15850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_15855	COG1120	ATPase activity
FY131_15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_15865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_15875	COG2375	cellular response to nickel ion
FY131_15885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY131_15890	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY131_15890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY131_15900	COG1169	isochorismate synthase
FY131_15905	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY131_15910	COG3433	isochorismatase activity
FY131_15910	COG1535	isochorismatase
FY131_15915	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_15945	COG0668	transmembrane transport
FY131_15955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY131_15965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY131_15965	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY131_15975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_15990	COG1609	Transcriptional regulator
FY131_15995	COG0673	inositol 2-dehydrogenase activity
FY131_16005	COG1653	transport
FY131_16010	COG1175	transmembrane transport
FY131_16015	COG0395	ABC-type sugar transport system, permease component
FY131_16020	COG3842	ATPase activity
FY131_16035	COG1253	flavin adenine dinucleotide binding
FY131_16065	COG3842	ATPase activity
FY131_16070	COG1178	ABC-type Fe3 transport system permease component
FY131_16095	COG0483	inositol monophosphate 1-phosphatase activity
FY131_16105	COG0477	Major facilitator Superfamily
FY131_16125	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_16135	COG1879	ABC-type sugar transport system periplasmic component
FY131_16145	COG1063	alcohol dehydrogenase
FY131_16150	COG1309	transcriptional regulator
FY131_16170	COG1312	Catalyzes the dehydration of D-mannonate
FY131_16175	COG0246	Mannitol dehydrogenase
FY131_16180	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_16195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_16205	COG1129	ABC transporter
FY131_16210	COG4977	sequence-specific DNA binding
FY131_16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_16220	COG4311	Sarcosine oxidase, delta subunit
FY131_16225	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY131_16225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY131_16245	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY131_16250	COG0318	PFAM AMP-dependent synthetase and ligase
FY131_16260	COG0367	asparagine synthase
FY131_16270	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY131_16275	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FY131_16300	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FY131_16305	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_16320	COG1609	Transcriptional regulator
FY131_16335	COG3300	MHYT domain
FY131_16335	COG5001	Diguanylate cyclase
FY131_16345	COG0840	transmembrane signaling receptor activity
FY131_16350	COG4166	transmembrane transport
FY131_16355	COG0601	transmembrane transport
FY131_16360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_16365	COG4172	Belongs to the ABC transporter superfamily
FY131_16385	COG2986	histidine ammonia-lyase
FY131_16415	COG1278	Cold shock
FY131_16435	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY131_16440	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY131_16445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY131_16450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY131_16455	COG2080	2 iron, 2 sulfur cluster binding
FY131_16470	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY131_16490	COG0346	lactoylglutathione lyase activity
FY131_16495	COG0583	DNA-binding transcription factor activity
FY131_16500	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY131_16515	COG1846	Transcriptional regulator
FY131_16520	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_16530	COG0583	DNA-binding transcription factor activity
FY131_16540	COG0783	Belongs to the Dps family
FY131_16545	COG2140	Oxalate decarboxylase
FY131_16555	COG4566	intracellular signal transduction
FY131_16570	COG0492	ferredoxin-NADP+ reductase activity
FY131_16580	COG2814	Major facilitator Superfamily
FY131_16585	COG0243	molybdopterin cofactor binding
FY131_16595	COG0604	alcohol dehydrogenase
FY131_16600	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_16605	COG1902	pentaerythritol trinitrate reductase activity
FY131_16610	COG4221	oxidoreductase activity
FY131_16615	COG1309	transcriptional regulator
FY131_16625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY131_16640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY131_16645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY131_16685	COG0741	lytic transglycosylase activity
FY131_16685	COG1196	nuclear chromosome segregation
FY131_16685	COG0739	heme binding
FY131_16690	COG0542	response to heat
FY131_16700	COG2890	protein-(glutamine-N5) methyltransferase activity
FY131_16705	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY131_16715	COG0527	aspartate kinase activity
FY131_16730	COG0019	diaminopimelate decarboxylase activity
FY131_16745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY131_16765	COG0784	Response regulator, receiver
FY131_16780	COG1522	sequence-specific DNA binding
FY131_16790	COG1116	anion transmembrane transporter activity
FY131_16795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_16800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY131_16805	COG1012	belongs to the aldehyde dehydrogenase family
FY131_16810	COG0583	DNA-binding transcription factor activity
FY131_16815	COG0435	Glutathione S-transferase
FY131_16825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY131_16830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_16835	COG0189	ligase activity
FY131_16860	COG0693	protein deglycase activity
FY131_16870	COG3685	Protein conserved in bacteria
FY131_16875	COG4993	Dehydrogenase
FY131_16895	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_16900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY131_16920	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY131_16930	COG0411	ABC transporter
FY131_16945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_16960	COG4608	Belongs to the ABC transporter superfamily
FY131_16965	COG0444	Belongs to the ABC transporter superfamily
FY131_16970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_16975	COG0601	transmembrane transport
FY131_16980	COG0747	negative chemotaxis
FY131_16985	COG0006	proline dipeptidase activity
FY131_16990	COG4221	oxidoreductase activity
FY131_17020	COG0539	negative regulation of cytoplasmic translation
FY131_17025	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY131_17055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY131_17060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY131_17090	COG1294	oxidase, subunit
FY131_17100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY131_17105	COG4988	ABC transporter
FY131_17115	COG1063	alcohol dehydrogenase
FY131_17120	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_17125	COG2084	Dehydrogenase
FY131_17135	COG1522	sequence-specific DNA binding
FY131_17140	COG1794	racemase activity, acting on amino acids and derivatives
FY131_17155	COG0058	SHG alpha-glucan phosphorylase activity
FY131_17160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY131_17165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY131_17170	COG0297	glycogen (starch) synthase activity
FY131_17175	COG0033	Phosphoglucomutase
FY131_17180	COG1523	belongs to the glycosyl hydrolase 13 family
FY131_17205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY131_17205	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY131_17220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_17225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY131_17245	COG1215	transferase activity, transferring glycosyl groups
FY131_17250	COG2327	Polysaccharide pyruvyl transferase
FY131_17255	COG0463	Glycosyl transferase, family 2
FY131_17260	COG2244	polysaccharide biosynthetic process
FY131_17265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY131_17270	COG2273	Hydrolase Family 16
FY131_17275	COG0438	transferase activity, transferring glycosyl groups
FY131_17280	COG1215	transferase activity, transferring glycosyl groups
FY131_17285	COG1215	transferase activity, transferring glycosyl groups
FY131_17290	COG1215	transferase activity, transferring glycosyl groups
FY131_17295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY131_17300	COG0489	protein tyrosine kinase activity
FY131_17300	COG3206	protein involved in exopolysaccharide biosynthesis
FY131_17310	COG0784	Response regulator, receiver
FY131_17310	COG4191	Histidine kinase
FY131_17320	COG4176	ABC-type proline glycine betaine transport system permease component
FY131_17325	COG0517	IMP dehydrogenase activity
FY131_17325	COG4175	Glycine betaine
FY131_17340	COG0564	pseudouridine synthase activity
FY131_17345	COG0500	methyltransferase
FY131_17355	COG2133	pyrroloquinoline quinone binding
FY131_17365	COG2197	response regulator
FY131_17370	COG4585	Histidine kinase
FY131_17375	COG1879	ABC-type sugar transport system periplasmic component
FY131_17380	COG1129	ABC transporter
FY131_17385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_17395	COG3386	PFAM SMP-30 Gluconolaconase
FY131_17400	COG2137	regulation of response to DNA damage stimulus
FY131_17415	COG1120	ATPase activity
FY131_17430	COG4774	siderophore transport
FY131_17435	COG0583	DNA-binding transcription factor activity
FY131_17445	COG2194	sulfuric ester hydrolase activity
FY131_17455	COG0642	Histidine kinase
FY131_17460	COG0477	Major facilitator Superfamily
FY131_17485	COG0673	inositol 2-dehydrogenase activity
FY131_17490	COG0697	spore germination
FY131_17500	COG0010	Belongs to the arginase family
FY131_17515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY131_17520	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY131_17525	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY131_17535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY131_17585	COG0671	phosphoesterase, PA-phosphatase related
FY131_17590	COG0745	RESPONSE REGULATOR receiver
FY131_17595	COG2205	protein histidine kinase activity
FY131_17615	COG0277	FAD linked oxidase domain protein
FY131_17630	COG0601	transmembrane transport
FY131_17635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_17640	COG4172	Belongs to the ABC transporter superfamily
FY131_17650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_17660	COG0477	Major facilitator Superfamily
FY131_17665	COG0583	DNA-binding transcription factor activity
FY131_17670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY131_17705	COG0673	inositol 2-dehydrogenase activity
FY131_17710	COG0673	inositol 2-dehydrogenase activity
FY131_17720	COG1175	transmembrane transport
FY131_17725	COG0395	ABC-type sugar transport system, permease component
FY131_17730	COG3842	ATPase activity
FY131_17740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_17745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY131_17755	COG0798	PFAM Bile acid sodium symporter
FY131_17765	COG0431	NADPH-dependent FMN reductase
FY131_17775	COG0640	Transcriptional regulator
FY131_17790	COG0765	amino acid transport
FY131_17800	COG1126	abc transporter atp-binding protein
FY131_17805	COG0010	Belongs to the arginase family
FY131_17810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY131_17815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_17820	COG1126	abc transporter atp-binding protein
FY131_17825	COG0765	amino acid transport
FY131_17830	COG0765	amino acid transport
FY131_17835	COG4221	oxidoreductase activity
FY131_17845	COG0436	Aminotransferase
FY131_17850	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY131_17855	COG1984	allophanate hydrolase subunit 2
FY131_17870	COG0439	Biotin carboxylase
FY131_17875	COG0511	ligase activity, forming carbon-carbon bonds
FY131_17915	COG0402	S-adenosylhomocysteine deaminase activity
FY131_17920	COG1228	amidohydrolase
FY131_17925	COG2986	histidine ammonia-lyase
FY131_17935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY131_17940	COG0596	Alpha beta hydrolase
FY131_17970	COG1192	Involved in chromosome partitioning
FY131_17975	COG1475	DNA binding
FY131_17980	COG1414	Transcriptional regulator
FY131_18000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY131_18005	COG4771	TonB-dependent receptor
FY131_18015	COG0366	Alpha amylase catalytic
FY131_18020	COG4770	biotin carboxylase activity
FY131_18025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY131_18030	COG4336	lyase activity
FY131_18035	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY131_18040	COG1914	H( )-stimulated, divalent metal cation uptake system
FY131_18045	COG1802	Transcriptional regulator
FY131_18050	COG3707	response regulator
FY131_18060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY131_18065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_18070	COG1116	anion transmembrane transporter activity
FY131_18075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY131_18085	COG0243	molybdopterin cofactor binding
FY131_18090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY131_18090	COG1648	precorrin-2 dehydrogenase activity
FY131_18105	COG3842	ATPase activity
FY131_18110	COG3842	ATPase activity
FY131_18120	COG0395	ABC-type sugar transport system, permease component
FY131_18135	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY131_18150	COG0071	Belongs to the small heat shock protein (HSP20) family
FY131_18180	COG1879	ABC-type sugar transport system periplasmic component
FY131_18185	COG1129	ABC transporter
FY131_18190	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_18200	COG0667	Aldo Keto reductase
FY131_18205	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY131_18210	COG1830	Aldolase
FY131_18215	COG1070	Carbohydrate kinase
FY131_18220	COG0840	transmembrane signaling receptor activity
FY131_18225	COG1846	Transcriptional regulator
FY131_18230	COG1304	FMN binding
FY131_18235	COG0488	(ABC) transporter
FY131_18250	COG2308	Evidence 4 Homologs of previously reported genes of
FY131_18250	COG2307	Protein conserved in bacteria
FY131_18300	COG1454	alcohol dehydrogenase
FY131_18305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY131_18315	COG0747	negative chemotaxis
FY131_18320	COG0601	transmembrane transport
FY131_18325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_18335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_18355	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY131_18360	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY131_18365	COG0069	glutamate synthase activity
FY131_18370	COG0174	glutamine synthetase
FY131_18390	COG0765	amino acid transport
FY131_18395	COG1126	abc transporter atp-binding protein
FY131_18410	COG2267	carboxylic ester hydrolase activity
FY131_18420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_18425	COG1012	belongs to the aldehyde dehydrogenase family
FY131_18445	COG1177	transmembrane transport
FY131_18450	COG3842	ATPase activity
FY131_18470	COG0583	DNA-binding transcription factor activity
FY131_18490	COG3239	Fatty acid desaturase
FY131_18515	COG2186	Transcriptional regulator
FY131_18520	COG1027	Aspartate ammonia-lyase
FY131_18530	COG0252	asparaginase activity
FY131_18545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY131_18550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY131_18555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY131_18560	COG2205	protein histidine kinase activity
FY131_18575	COG0067	glutamate synthase
FY131_18575	COG0069	glutamate synthase activity
FY131_18575	COG0070	glutamate synthase
FY131_18590	COG2205	protein histidine kinase activity
FY131_18605	COG2951	lytic endotransglycosylase activity
FY131_18610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY131_18635	COG0330	HflC and HflK could
FY131_18640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY131_18645	COG0737	Belongs to the 5'-nucleotidase family
FY131_18655	COG5310	Homospermidine synthase
FY131_18665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY131_18670	COG1164	Oligoendopeptidase f
FY131_18675	COG2204	response regulator
FY131_18680	COG3108	Peptidase M15
FY131_18685	COG0469	pyruvate kinase activity
FY131_18705	COG3750	Belongs to the UPF0335 family
FY131_18710	COG0457	Tetratricopeptide repeat
FY131_18715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY131_18720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY131_18725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY131_18755	COG0483	inositol monophosphate 1-phosphatase activity
FY131_18775	COG1132	(ABC) transporter
FY131_18780	COG0254	rRNA binding
FY131_18800	COG3588	fructose-bisphosphate aldolase
FY131_18805	COG0126	phosphoglycerate kinase activity
FY131_18845	COG1253	flavin adenine dinucleotide binding
FY131_18855	COG1692	metallophosphoesterase
FY131_18870	COG0217	transcriptional regulatory protein
FY131_18875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_18880	COG0840	transmembrane signaling receptor activity
FY131_18880	COG2972	Histidine kinase
FY131_18885	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY131_18890	COG0632	four-way junction helicase activity
FY131_18895	COG2255	four-way junction helicase activity
FY131_18910	COG0494	nUDIX hydrolase
FY131_18920	COG0824	Thioesterase
FY131_18940	COG0823	Involved in the tonB-independent uptake of proteins
FY131_18945	COG2885	chlorophyll binding
FY131_18955	COG0037	tRNA processing
FY131_18960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY131_18965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY131_18980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY131_18995	COG0482	sulfurtransferase activity
FY131_19015	COG3118	belongs to the thioredoxin family
FY131_19025	COG2835	tetraacyldisaccharide 4'-kinase activity
FY131_19030	COG2373	Large extracellular alpha-helical protein
FY131_19035	COG4953	penicillin-binding protein 1C
FY131_19045	COG1473	amidohydrolase
FY131_19145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_19180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_19185	COG1686	Belongs to the peptidase S11 family
FY131_19190	COG0523	cobalamin synthesis protein
FY131_19195	COG0425	Belongs to the sulfur carrier protein TusA family
FY131_19200	COG3034	peptidoglycan biosynthetic process
FY131_19205	COG0825	malonyl-CoA metabolic process
FY131_19210	COG4974	Belongs to the 'phage' integrase family
FY131_19220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY131_19225	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY131_19260	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY131_19265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY131_19280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY131_19285	COG2226	methyltransferase
FY131_19290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY131_19295	COG0287	Prephenate dehydrogenase
FY131_19310	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY131_19330	COG2884	Cell division ATP-binding protein ftsE
FY131_19365	COG0165	Argininosuccinate lyase
FY131_19370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY131_19375	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY131_19385	COG2086	electron transfer activity
FY131_19395	COG2096	Adenosyltransferase
FY131_19405	COG0300	oxidoreductase activity
FY131_19415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY131_19425	COG1396	sequence-specific DNA binding
FY131_19425	COG3800	Transcriptional regulator
FY131_19430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY131_19435	COG0625	glutathione transferase activity
FY131_19445	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY131_19450	COG4770	biotin carboxylase activity
FY131_19455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY131_19455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY131_19460	COG0346	lactoylglutathione lyase activity
FY131_19470	COG0640	Transcriptional regulator
FY131_19485	COG4213	ABC transporter substrate-binding protein
FY131_19490	COG4214	carbohydrate transport
FY131_19495	COG1129	ABC transporter
FY131_19505	COG1396	sequence-specific DNA binding
FY131_19560	COG3833	ABC-type maltose transport systems, permease component
FY131_19565	COG3842	ATPase activity
FY131_19580	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY131_19580	COG2273	Hydrolase Family 16
FY131_19585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY131_19600	COG0438	transferase activity, transferring glycosyl groups
FY131_19605	COG0438	transferase activity, transferring glycosyl groups
FY131_19645	COG2244	polysaccharide biosynthetic process
FY131_19710	COG0653	protein targeting
FY131_19715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY131_19720	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY131_19730	COG0494	nUDIX hydrolase
FY131_19745	COG2226	methyltransferase
FY131_19750	COG1040	competence protein
FY131_19760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY131_19770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY131_19790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY131_19795	COG4150	thiosulfate binding
FY131_19805	COG4208	sulfate ABC transporter
FY131_19810	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY131_19815	COG4335	DNA alkylation repair
FY131_19830	COG5001	Diguanylate cyclase
FY131_19835	COG2264	protein methyltransferase activity
FY131_19850	COG3254	rhamnose metabolic process
FY131_19855	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_19860	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_19865	COG1129	ABC transporter
FY131_19875	COG1349	DNA-binding transcription factor activity
FY131_19880	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_19880	COG3347	Dehydrogenase
FY131_19885	COG4952	isomerase
FY131_19890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY131_19895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY131_19900	COG1024	Enoyl-CoA hydratase
FY131_19915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY131_19920	COG1960	acyl-CoA dehydrogenase activity
FY131_19930	COG0183	Belongs to the thiolase family
FY131_19935	COG1960	acyl-CoA dehydrogenase activity
FY131_19945	COG0022	dehydrogenase e1 component
FY131_19955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY131_19960	COG2391	methyltransferase activity
FY131_19970	COG0640	Transcriptional regulator
FY131_19975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY131_19975	COG3453	Protein conserved in bacteria
FY131_19985	COG0300	oxidoreductase activity
FY131_20000	COG2186	Transcriptional regulator
FY131_20010	COG0601	transmembrane transport
FY131_20020	COG0444	Belongs to the ABC transporter superfamily
FY131_20025	COG4608	Belongs to the ABC transporter superfamily
FY131_20045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20070	COG1473	amidohydrolase
FY131_20075	COG0747	negative chemotaxis
FY131_20095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20100	COG0583	DNA-binding transcription factor activity
FY131_20110	COG0667	Aldo Keto reductase
FY131_20120	COG0444	Belongs to the ABC transporter superfamily
FY131_20145	COG1960	acyl-CoA dehydrogenase activity
FY131_20165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY131_20180	COG1959	2 iron, 2 sulfur cluster binding
FY131_20185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20195	COG1473	amidohydrolase
FY131_20205	COG1126	abc transporter atp-binding protein
FY131_20210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_20225	COG1522	sequence-specific DNA binding
FY131_20230	COG4172	Belongs to the ABC transporter superfamily
FY131_20235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_20240	COG0601	transmembrane transport
FY131_20270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_20275	COG1012	belongs to the aldehyde dehydrogenase family
FY131_20280	COG0473	3-isopropylmalate dehydrogenase activity
FY131_20285	COG1012	belongs to the aldehyde dehydrogenase family
FY131_20300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY131_20320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_20325	COG1120	ATPase activity
FY131_20335	COG2226	methyltransferase
FY131_20350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_20355	COG1120	ATPase activity
FY131_20360	COG1595	DNA-templated transcription, initiation
FY131_20370	COG4771	TonB-dependent receptor
FY131_20380	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY131_20385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_20390	COG2197	response regulator
FY131_20395	COG0601	transmembrane transport
FY131_20400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_20420	COG0747	negative chemotaxis
FY131_20435	COG1446	asparaginase
FY131_20440	COG0583	DNA-binding transcription factor activity
FY131_20445	COG0601	transmembrane transport
FY131_20450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_20465	COG0747	negative chemotaxis
FY131_20470	COG1473	amidohydrolase
FY131_20480	COG1129	ABC transporter
FY131_20485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_20490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY131_20495	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY131_20505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY131_20525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_20535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_20540	COG2079	MmgE PrpD family protein
FY131_20545	COG1126	abc transporter atp-binding protein
FY131_20550	COG0765	amino acid transport
FY131_20565	COG0280	phosphate acetyltransferase
FY131_20565	COG0281	malic enzyme
FY131_20570	COG0583	DNA-binding transcription factor activity
FY131_20595	COG1175	transmembrane transport
FY131_20600	COG0395	ABC-type sugar transport system, permease component
FY131_20615	COG0673	inositol 2-dehydrogenase activity
FY131_20620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY131_20625	COG0720	synthase
FY131_20630	COG0602	queuosine metabolic process
FY131_20635	COG0673	inositol 2-dehydrogenase activity
FY131_20645	COG3842	ATPase activity
FY131_20660	COG1653	transport
FY131_20665	COG1609	Transcriptional regulator
FY131_20675	COG2094	Belongs to the DNA glycosylase MPG family
FY131_20685	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_20695	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_20700	COG0840	transmembrane signaling receptor activity
FY131_20705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY131_20720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY131_20725	COG1596	polysaccharide export
FY131_20730	COG3307	-O-antigen
FY131_20770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_20795	COG2942	2-epimerase
FY131_20805	COG1215	transferase activity, transferring glycosyl groups
FY131_20825	COG1473	amidohydrolase
FY131_20835	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_20840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY131_20850	COG1301	dicarboxylic acid transport
FY131_20855	COG4191	Histidine kinase
FY131_20860	COG2204	response regulator
FY131_20875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_20880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY131_20885	COG1522	sequence-specific DNA binding
FY131_20890	COG0351	phosphomethylpyrimidine kinase
FY131_20895	COG0352	thiamine-phosphate diphosphorylase activity
FY131_20900	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY131_20905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY131_20910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_20920	COG1501	Belongs to the glycosyl hydrolase 31 family
FY131_20925	COG0395	ABC-type sugar transport system, permease component
FY131_20930	COG1175	transmembrane transport
FY131_20935	COG1653	transport
FY131_20940	COG3842	ATPase activity
FY131_20945	COG2188	Transcriptional regulator
FY131_20955	COG4989	oxidoreductase activity
FY131_20995	COG0438	transferase activity, transferring glycosyl groups
FY131_21005	COG0747	negative chemotaxis
FY131_21010	COG0601	transmembrane transport
FY131_21020	COG3964	amidohydrolase
FY131_21035	COG1921	L-seryl-tRNASec selenium transferase activity
FY131_21045	COG0625	glutathione transferase activity
FY131_21060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_21065	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY131_21065	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY131_21070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY131_21085	COG1312	Catalyzes the dehydration of D-mannonate
FY131_21090	COG1063	alcohol dehydrogenase
FY131_21095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY131_21105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY131_21110	COG2186	Transcriptional regulator
FY131_21115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY131_21120	COG0850	regulation of cytokinetic process
FY131_21125	COG2894	cell division
FY131_21130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY131_21145	COG5001	Diguanylate cyclase
FY131_21160	COG0673	inositol 2-dehydrogenase activity
FY131_21165	COG1846	Transcriptional regulator
FY131_21165	COG1940	carbohydrate kinase activity
FY131_21170	COG1653	transport
FY131_21175	COG1175	transmembrane transport
FY131_21180	COG0395	ABC-type sugar transport system, permease component
FY131_21185	COG3842	ATPase activity
FY131_21195	COG0673	inositol 2-dehydrogenase activity
FY131_21230	COG0587	DNA-directed DNA polymerase activity
FY131_21245	COG2186	Transcriptional regulator
FY131_21250	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_21255	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_21260	COG1129	ABC transporter
FY131_21265	COG1879	ABC-type sugar transport system periplasmic component
FY131_21270	COG0129	dihydroxy-acid dehydratase activity
FY131_21280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY131_21285	COG4608	Belongs to the ABC transporter superfamily
FY131_21290	COG0444	Belongs to the ABC transporter superfamily
FY131_21295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_21300	COG0601	transmembrane transport
FY131_21305	COG0747	negative chemotaxis
FY131_21315	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY131_21320	COG5001	Diguanylate cyclase
FY131_21330	COG3257	ureidoglycine aminohydrolase activity
FY131_21335	COG3447	MASE1 domain protein
FY131_21335	COG5001	Diguanylate cyclase
FY131_21335	COG5002	protein histidine kinase activity
FY131_21340	COG1129	ABC transporter
FY131_21345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_21350	COG1879	ABC-type sugar transport system periplasmic component
FY131_21355	COG0583	DNA-binding transcription factor activity
FY131_21380	COG3047	cAMP biosynthetic process
FY131_21390	COG3842	ATPase activity
FY131_21395	COG0395	ABC-type sugar transport system, permease component
FY131_21400	COG1175	transmembrane transport
FY131_21405	COG1653	transport
FY131_21410	COG0523	cobalamin synthesis protein
FY131_21425	COG0523	cobalamin synthesis protein
FY131_21430	COG1121	(ABC) transporter
FY131_21440	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY131_21450	COG0626	cystathionine gamma-synthase activity
FY131_21455	COG2182	Extracellular solute-binding protein
FY131_21465	COG0395	ABC-type sugar transport system, permease component
FY131_21480	COG0395	ABC-type sugar transport system, permease component
FY131_21485	COG1175	transmembrane transport
FY131_21490	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY131_21495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY131_21505	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_21510	COG1063	alcohol dehydrogenase
FY131_21515	COG1609	Transcriptional regulator
FY131_21530	COG2084	Dehydrogenase
FY131_21535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY131_21545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY131_21550	COG0583	DNA-binding transcription factor activity
FY131_21555	COG2223	nitrite transmembrane transporter activity
FY131_21590	COG0667	Aldo Keto reductase
FY131_21605	COG2186	Transcriptional regulator
FY131_21610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_21615	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY131_21620	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_21625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_21630	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_21635	COG3618	amidohydrolase
FY131_21640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY131_21660	COG1175	transmembrane transport
FY131_21665	COG0395	ABC-type sugar transport system, permease component
FY131_21670	COG3842	ATPase activity
FY131_21685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY131_21690	COG2205	protein histidine kinase activity
FY131_21710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_21715	COG0577	efflux transmembrane transporter activity
FY131_21715	COG1136	(ABC) transporter
FY131_21720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY131_21750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY131_21760	COG1278	Cold shock
FY131_21765	COG0673	inositol 2-dehydrogenase activity
FY131_21780	COG0673	inositol 2-dehydrogenase activity
FY131_21785	COG1309	transcriptional regulator
FY131_21790	COG1653	transport
FY131_21795	COG1175	transmembrane transport
FY131_21800	COG0395	ABC-type sugar transport system, permease component
FY131_21805	COG3842	ATPase activity
FY131_21810	COG1082	Xylose isomerase domain protein TIM barrel
FY131_21825	COG1609	Transcriptional regulator
FY131_21855	COG1175	transmembrane transport
FY131_21860	COG0395	ABC-type sugar transport system, permease component
FY131_21865	COG1116	anion transmembrane transporter activity
FY131_21870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_21875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY131_21885	COG3842	ATPase activity
FY131_21890	COG0395	ABC-type sugar transport system, permease component
FY131_21895	COG1175	transmembrane transport
FY131_21900	COG1653	transport
FY131_21930	COG3284	Transcriptional regulator
FY131_21935	COG1063	alcohol dehydrogenase
FY131_21950	COG2186	Transcriptional regulator
FY131_21955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_21960	COG0765	amino acid transport
FY131_21965	COG0765	amino acid transport
FY131_21975	COG3842	ATPase activity
FY131_21985	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY131_21990	COG0395	ABC-type sugar transport system, permease component
FY131_22000	COG1595	DNA-templated transcription, initiation
FY131_22040	COG2186	Transcriptional regulator
FY131_22045	COG0747	negative chemotaxis
FY131_22050	COG0601	transmembrane transport
FY131_22055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_22060	COG0405	Gamma-glutamyltransferase
FY131_22070	COG0784	Response regulator, receiver
FY131_22070	COG2198	Histidine kinase
FY131_22070	COG5002	protein histidine kinase activity
FY131_22090	COG1278	Cold shock
FY131_22110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_22115	COG0601	transmembrane transport
FY131_22120	COG0747	negative chemotaxis
FY131_22130	COG0583	DNA-binding transcription factor activity
FY131_22150	COG0583	DNA-binding transcription factor activity
FY131_22155	COG0477	Major facilitator Superfamily
FY131_22170	COG1522	sequence-specific DNA binding
FY131_22200	COG0747	negative chemotaxis
FY131_22205	COG0601	transmembrane transport
FY131_22210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_22215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_22245	COG3842	ATPase activity
FY131_22250	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY131_22255	COG1177	transmembrane transport
FY131_22260	COG4303	Ethanolamine ammonia lyase large subunit
FY131_22270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY131_22280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY131_22290	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY131_22310	COG4178	(ABC) transporter
FY131_22350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_22375	COG2197	response regulator
FY131_22380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY131_22385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY131_22395	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY131_22400	COG4310	Domain of unknown function (DUF2172)
FY131_22405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY131_22410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY131_22415	COG2197	response regulator
FY131_22450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY131_22470	COG0438	transferase activity, transferring glycosyl groups
FY131_22485	COG0071	Belongs to the small heat shock protein (HSP20) family
FY131_22495	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_22505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY131_22515	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_22525	COG1653	transport
FY131_22530	COG0395	ABC-type sugar transport system, permease component
FY131_22535	COG4209	transmembrane transport
FY131_22540	COG3842	ATPase activity
FY131_22545	COG1802	Transcriptional regulator
FY131_22550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_22565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_22570	COG0765	amino acid transport
FY131_22580	COG1126	abc transporter atp-binding protein
FY131_22585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY131_22590	COG1027	Aspartate ammonia-lyase
FY131_22600	COG4172	Belongs to the ABC transporter superfamily
FY131_22605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_22610	COG0601	transmembrane transport
FY131_22615	COG0747	negative chemotaxis
FY131_22650	COG1522	sequence-specific DNA binding
FY131_22670	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_22675	COG0318	PFAM AMP-dependent synthetase and ligase
FY131_22685	COG1414	Transcriptional regulator
FY131_22695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY131_22705	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FY131_22715	COG1764	response to oxidative stress
FY131_22740	COG0596	Alpha beta hydrolase
FY131_22770	COG2814	Major facilitator Superfamily
FY131_22775	COG1162	GTPase activity
FY131_22815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FY131_22840	COG3547	Transposase (IS116 IS110 IS902 family)
FY131_22930	COG1484	DNA-dependent DNA replication
FY131_22935	COG4584	PFAM Integrase catalytic
FY131_22965	COG1051	belongs to the nudix hydrolase family
FY131_22990	COG1192	Involved in chromosome partitioning
FY131_22995	COG1475	DNA binding
FY131_23000	COG0640	Transcriptional regulator
FY131_23025	COG0583	DNA-binding transcription factor activity
FY131_23075	COG3971	2-oxopent-4-enoate hydratase activity
FY131_23080	COG3485	protocatechuate 3,4-dioxygenase
FY131_23115	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_23145	COG4566	intracellular signal transduction
FY131_23210	COG2068	MobA-Related Protein
FY131_23215	COG4566	intracellular signal transduction
FY131_23220	COG0477	Major facilitator Superfamily
FY131_23225	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY131_23250	COG2814	Major facilitator Superfamily
FY131_23255	COG3474	cytochrome
FY131_23275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY131_23295	COG1733	regulation of RNA biosynthetic process
FY131_23300	COG3920	Histidine kinase
FY131_23345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY131_23375	COG2249	NAD(P)H dehydrogenase (quinone) activity
FY131_23385	COG2010	Cytochrome c
FY131_23385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY131_23400	COG0667	Aldo Keto reductase
FY131_23405	COG2814	Major facilitator Superfamily
FY131_23410	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY131_23415	COG0596	Alpha beta hydrolase
FY131_23425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_23460	COG0583	DNA-binding transcription factor activity
FY131_23470	COG1116	anion transmembrane transporter activity
FY131_23475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_23485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY131_23500	COG0583	DNA-binding transcription factor activity
FY131_23525	COG0210	DNA helicase
FY131_23555	COG0784	Response regulator, receiver
FY131_23555	COG4191	Histidine kinase
FY131_23575	COG2814	Major facilitator Superfamily
FY131_23595	COG1104	cysteine desulfurase activity
FY131_23605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY131_23610	COG0494	nUDIX hydrolase
FY131_23615	COG0284	orotidine-5'-phosphate decarboxylase activity
FY131_23625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY131_23630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY131_23655	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FY131_23660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_23675	COG0167	dihydroorotate dehydrogenase activity
FY131_23710	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_23715	COG1733	regulation of RNA biosynthetic process
FY131_23725	COG0477	Major facilitator Superfamily
FY131_23730	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_23735	COG1794	racemase activity, acting on amino acids and derivatives
FY131_23745	COG0300	oxidoreductase activity
FY131_23760	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
FY131_23765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY131_23780	COG1605	Chorismate mutase
FY131_23780	COG0287	Prephenate dehydrogenase
FY131_23785	COG0583	DNA-binding transcription factor activity
FY131_23790	COG0300	oxidoreductase activity
FY131_23805	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_23815	COG0251	oxidation-reduction process
FY131_23840	COG3547	Transposase (IS116 IS110 IS902 family)
FY131_23855	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_23860	COG0668	transmembrane transport
FY131_23890	COG3609	addiction module antidote protein, CC2985 family
FY131_23905	COG2072	flavoprotein involved in K transport
FY131_23915	COG2144	transferase activity, transferring acyl groups
FY131_23925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY131_23940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY131_23955	COG3177	Filamentation induced by cAMP protein fic
FY131_23960	COG1120	ATPase activity
FY131_23965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_23970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY131_23975	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY131_23980	COG4772	TonB-dependent receptor
FY131_24010	COG0747	negative chemotaxis
FY131_24015	COG0601	transmembrane transport
FY131_24020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_24030	COG4608	Belongs to the ABC transporter superfamily
FY131_24050	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY131_24065	COG2249	NAD(P)H dehydrogenase (quinone) activity
FY131_24070	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY131_24075	COG0402	S-adenosylhomocysteine deaminase activity
FY131_24080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY131_24115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY131_24120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY131_24130	COG3608	succinylglutamate desuccinylase aspartoacylase
FY131_24130	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY131_24135	COG2068	MobA-Related Protein
FY131_24150	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY131_24155	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY131_24160	COG2080	2 iron, 2 sulfur cluster binding
FY131_24165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY131_24180	COG0583	DNA-binding transcription factor activity
FY131_24185	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_24195	COG0583	DNA-binding transcription factor activity
FY131_24200	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY131_24205	COG0667	Aldo Keto reductase
FY131_24215	COG0110	maltose O-acetyltransferase activity
FY131_24220	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_24225	COG1309	transcriptional regulator
FY131_24240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY131_24245	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY131_24250	COG2080	2 iron, 2 sulfur cluster binding
FY131_24290	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_24295	COG0667	Aldo Keto reductase
FY131_24305	COG2814	Major facilitator Superfamily
FY131_24310	COG2207	Transcriptional regulator
FY131_24315	COG2207	Transcriptional regulator
FY131_24320	COG1396	sequence-specific DNA binding
FY131_24335	COG1902	pentaerythritol trinitrate reductase activity
FY131_24340	COG1609	Transcriptional regulator
FY131_24350	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_24365	COG0673	inositol 2-dehydrogenase activity
FY131_24375	COG1802	Transcriptional regulator
FY131_24410	COG2207	Transcriptional regulator
FY131_24425	COG0596	Alpha beta hydrolase
FY131_24455	COG0840	transmembrane signaling receptor activity
FY131_24465	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_24490	COG0587	DNA-directed DNA polymerase activity
FY131_24510	COG5489	Protein of unknown function (DUF736)
FY131_24520	COG1505	serine-type exopeptidase activity
FY131_24530	COG0776	regulation of translation
FY131_24535	COG3831	ATPase activity
FY131_24540	COG3505	Type IV secretory pathway VirD4
FY131_24605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY131_24605	COG0475	glutathione-regulated potassium exporter activity
FY131_24620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY131_24665	COG0156	8-amino-7-oxononanoate synthase activity
FY131_24670	COG0745	RESPONSE REGULATOR receiver
FY131_24675	COG0745	RESPONSE REGULATOR receiver
FY131_24680	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_24685	COG0028	Belongs to the TPP enzyme family
FY131_24690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY131_24700	COG3842	ATPase activity
FY131_24705	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY131_24715	COG1840	ABC-type Fe3 transport system, periplasmic component
FY131_24725	COG0577	efflux transmembrane transporter activity
FY131_24735	COG1414	Transcriptional regulator
FY131_24745	COG1454	alcohol dehydrogenase
FY131_24750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY131_24785	COG1285	pathogenesis
FY131_24805	COG1733	regulation of RNA biosynthetic process
FY131_24830	COG4372	Transposase
FY131_24835	COG3436	PFAM IS66 Orf2 family protein
FY131_24840	COG2963	transposase activity
FY131_24880	COG3838	Conjugal transfer protein Trbc
FY131_24885	COG3702	type iv secretory pathway
FY131_24890	COG3451	type IV secretory pathway VirB4
FY131_24905	COG3704	protein secretion by the type IV secretion system
FY131_24915	COG3736	Type IV secretory pathway, component VirB8
FY131_24920	COG3504	Conjugal transfer protein
FY131_24925	COG2948	multi-organism process
FY131_24930	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY131_24955	COG2433	Pfam Transposase IS66
FY131_24960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY131_24965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY131_24975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY131_24995	COG0784	Response regulator, receiver
FY131_24995	COG4191	Histidine kinase
FY131_25010	COG4691	Plasmid stability protein
FY131_25015	COG1487	ribonuclease activity
FY131_25020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_25030	COG2186	Transcriptional regulator
FY131_25035	COG0747	negative chemotaxis
FY131_25040	COG0601	transmembrane transport
FY131_25045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_25050	COG4172	Belongs to the ABC transporter superfamily
FY131_25055	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_25080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY131_25085	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY131_25100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY131_25130	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY131_25135	COG3842	ATPase activity
FY131_25140	COG0483	inositol monophosphate 1-phosphatase activity
FY131_25145	COG0628	permease
FY131_25160	COG3734	2-keto-3-deoxy-galactonokinase
FY131_25165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY131_25170	COG4948	Mandelate Racemase Muconate Lactonizing
FY131_25180	COG1175	transmembrane transport
FY131_25185	COG0395	ABC-type sugar transport system, permease component
FY131_25190	COG3842	ATPase activity
FY131_25195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY131_25200	COG1414	Transcriptional regulator
FY131_25205	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_25210	COG2207	Transcriptional regulator
FY131_25225	COG0583	DNA-binding transcription factor activity
FY131_25230	COG0667	Aldo Keto reductase
FY131_25235	COG0583	DNA-binding transcription factor activity
FY131_25240	COG0604	alcohol dehydrogenase
FY131_25245	COG1609	Transcriptional regulator
FY131_25250	COG1082	Xylose isomerase domain protein TIM barrel
FY131_25255	COG0673	inositol 2-dehydrogenase activity
FY131_25260	COG1082	Xylose isomerase domain protein TIM barrel
FY131_25270	COG0405	Gamma-glutamyltransferase
FY131_25280	COG1215	transferase activity, transferring glycosyl groups
FY131_25315	COG2390	Transcriptional regulator
FY131_25320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY131_25325	COG3958	Transketolase
FY131_25330	COG3959	Transketolase, thiamine diphosphate binding domain
FY131_25335	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_25345	COG1129	ABC transporter
FY131_25350	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_25355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY131_25385	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_25405	COG0583	DNA-binding transcription factor activity
FY131_25420	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FY131_25425	COG1741	Belongs to the pirin family
FY131_25430	COG1335	isochorismatase
FY131_25435	COG0583	DNA-binding transcription factor activity
FY131_25440	COG1733	regulation of RNA biosynthetic process
FY131_25445	COG3321	synthase
FY131_25445	COG0604	alcohol dehydrogenase
FY131_25445	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_25450	COG0583	DNA-binding transcription factor activity
FY131_25470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY131_25470	COG1017	nitric oxide dioxygenase activity
FY131_25475	COG0625	glutathione transferase activity
FY131_25485	COG0583	DNA-binding transcription factor activity
FY131_25510	COG1349	DNA-binding transcription factor activity
FY131_25515	COG1879	ABC-type sugar transport system periplasmic component
FY131_25520	COG1129	ABC transporter
FY131_25525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_25530	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_25550	COG1012	belongs to the aldehyde dehydrogenase family
FY131_25560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY131_25615	COG0668	transmembrane transport
FY131_25630	COG1566	PFAM secretion protein HlyD family protein
FY131_25655	COG2207	Transcriptional regulator
FY131_25665	COG4302	ethanolamine ammonia-lyase activity
FY131_25670	COG4303	Ethanolamine ammonia lyase large subunit
FY131_25690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY131_25695	COG1349	DNA-binding transcription factor activity
FY131_25700	COG4608	Belongs to the ABC transporter superfamily
FY131_25710	COG0601	transmembrane transport
FY131_25715	COG0747	negative chemotaxis
FY131_25725	COG3842	ATPase activity
FY131_25730	COG1063	alcohol dehydrogenase
FY131_25735	COG0395	ABC-type sugar transport system, permease component
FY131_25740	COG1175	transmembrane transport
FY131_25745	COG1653	transport
FY131_25775	COG0326	Molecular chaperone. Has ATPase activity
FY131_25785	COG1881	PFAM PEBP family protein
FY131_25815	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY131_25840	COG2132	Multicopper oxidase
FY131_25915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_25930	COG2826	transposase and inactivated derivatives, IS30 family
FY131_25950	COG0583	DNA-binding transcription factor activity
FY131_25955	COG0667	Aldo Keto reductase
FY131_25990	COG1278	Cold shock
FY131_26005	COG1126	abc transporter atp-binding protein
FY131_26010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY131_26015	COG1609	Transcriptional regulator
FY131_26020	COG1192	Involved in chromosome partitioning
FY131_26025	COG1475	DNA binding
FY131_26030	COG0640	Transcriptional regulator
FY131_26035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_26100	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY131_26105	COG1129	ABC transporter
FY131_26130	COG4172	Belongs to the ABC transporter superfamily
FY131_26135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_26140	COG0601	transmembrane transport
FY131_26155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY131_26160	COG0583	DNA-binding transcription factor activity
FY131_26170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY131_26185	COG1132	(ABC) transporter
FY131_26190	COG4172	Belongs to the ABC transporter superfamily
FY131_26195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_26215	COG1082	Xylose isomerase domain protein TIM barrel
FY131_26220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY131_26225	COG0019	diaminopimelate decarboxylase activity
FY131_26235	COG1475	DNA binding
FY131_26245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY131_26335	COG1733	regulation of RNA biosynthetic process
FY131_26345	COG1475	DNA binding
FY131_26365	COG2824	Alkylphosphonate utilization operon protein PhnA
FY131_26385	COG5489	Protein of unknown function (DUF736)
FY131_26410	COG0494	nUDIX hydrolase
FY131_26415	COG5489	Protein of unknown function (DUF736)
FY131_26500	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY131_26515	COG0747	negative chemotaxis
FY131_26535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_26540	COG0584	glycerophosphoryl diester phosphodiesterase
FY131_26545	COG0483	inositol monophosphate 1-phosphatase activity
FY131_26605	COG3161	chorismate lyase activity
FY131_26880	COG0145	ligase activity
FY131_26890	COG0583	DNA-binding transcription factor activity
FY131_26940	COG3701	Conjugal transfer protein
FY131_26945	COG3846	protein secretion by the type IV secretion system
FY131_26955	COG5314	conjugation
FY131_26960	COG3451	type IV secretory pathway VirB4
FY131_26975	COG4962	Type ii secretion system protein e
FY131_26985	COG1192	Involved in chromosome partitioning
FY131_26990	COG1475	DNA binding
FY131_26995	COG0640	Transcriptional regulator
FY131_27000	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
FY131_27055	COG4584	PFAM Integrase catalytic
FY131_27130	COG1175	transmembrane transport
FY131_27150	COG1940	carbohydrate kinase activity
FY131_27160	COG3616	Alanine racemase, N-terminal domain
FY131_27175	COG0583	DNA-binding transcription factor activity
FY131_27180	COG1335	isochorismatase
FY131_27195	COG1252	NADH dehydrogenase
FY131_27200	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_27205	COG0583	DNA-binding transcription factor activity
FY131_27210	COG1902	pentaerythritol trinitrate reductase activity
FY131_27215	COG0583	DNA-binding transcription factor activity
FY131_27265	COG0235	Class ii aldolase
FY131_27330	COG0784	Response regulator, receiver
FY131_27330	COG4191	Histidine kinase
FY131_27340	COG2423	ornithine cyclodeaminase activity
FY131_27345	COG0583	DNA-binding transcription factor activity
FY131_27360	COG0765	amino acid transport
FY131_27365	COG0765	amino acid transport
FY131_27370	COG1126	abc transporter atp-binding protein
FY131_27375	COG0251	oxidation-reduction process
FY131_27380	COG3293	Transposase
FY131_27415	COG4702	Belongs to the UPF0303 family
FY131_27425	COG3842	ATPase activity
FY131_27430	COG1940	carbohydrate kinase activity
FY131_27435	COG0395	ABC-type sugar transport system, permease component
FY131_27440	COG1175	transmembrane transport
FY131_27450	COG2222	sugar isomerase
FY131_27455	COG1940	carbohydrate kinase activity
FY131_27460	COG0673	inositol 2-dehydrogenase activity
FY131_27540	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_27545	COG0154	amidase activity
FY131_27555	COG0583	DNA-binding transcription factor activity
FY131_27560	COG0747	negative chemotaxis
FY131_27565	COG0601	transmembrane transport
FY131_27570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY131_27605	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FY131_27615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY131_27625	COG0277	FAD linked oxidase domain protein
FY131_27630	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY131_27650	COG1012	belongs to the aldehyde dehydrogenase family
FY131_27690	COG1846	Transcriptional regulator
FY131_27720	COG1475	DNA binding
FY131_27745	COG5489	Protein of unknown function (DUF736)
FY131_27755	COG3831	ATPase activity
FY131_27765	COG1051	belongs to the nudix hydrolase family
FY131_27775	COG3505	Type IV secretory pathway VirD4
FY131_27790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY131_27795	COG4959	Type IV secretory pathway protease TraF
FY131_27800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY131_27820	COG1476	TRANSCRIPTIONal
FY131_27835	COG2948	multi-organism process
FY131_27850	COG3701	Conjugal transfer protein
FY131_27855	COG3846	protein secretion by the type IV secretion system
FY131_27865	COG5314	conjugation
FY131_27870	COG3451	type IV secretory pathway VirB4
FY131_27875	COG5268	conjugation
FY131_27880	COG3838	Conjugal transfer protein Trbc
FY131_27885	COG4962	Type ii secretion system protein e
FY131_27890	COG3916	Acyl-homoserine-lactone synthase
FY131_27895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY131_27900	COG4232	protein-disulfide reductase activity
FY131_27925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY131_27925	COG3453	Protein conserved in bacteria
FY131_27945	COG0730	response to heat
FY131_27955	COG0071	Belongs to the small heat shock protein (HSP20) family
FY131_27965	COG2132	Multicopper oxidase
FY131_28100	COG0741	lytic transglycosylase activity
FY131_28115	COG3451	type IV secretory pathway VirB4
FY131_28120	COG0741	lytic transglycosylase activity
FY131_28150	COG2948	multi-organism process
FY131_28155	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY131_28200	COG4644	lycopene metabolic process
FY131_28230	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY131_28250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY131_28275	COG0640	Transcriptional regulator
FY131_28280	COG1475	DNA binding
FY131_28285	COG1192	Involved in chromosome partitioning
FY131_28290	COG4227	nucleotidyltransferase activity
FY131_28295	COG2184	nucleotidyltransferase activity
FY131_28325	COG1793	dna ligase
FY131_28325	COG3285	dna ligase
FY131_28390	COG1051	belongs to the nudix hydrolase family
FY131_28405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FY131_28410	COG2801	Transposase and inactivated derivatives
FY131_28415	COG2124	cytochrome p450
FY131_28425	COG0785	Cytochrome C biogenesis protein
FY131_28435	COG1230	cation diffusion facilitator family transporter
FY131_28440	COG0640	Transcriptional regulator
FY131_28445	COG1522	sequence-specific DNA binding
FY131_28455	COG3453	Protein conserved in bacteria
FY131_28455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY131_28470	COG3034	peptidoglycan biosynthetic process
FY131_28485	COG0789	Transcriptional regulator
FY131_28490	COG0789	Transcriptional regulator
FY131_28495	COG2124	cytochrome p450
FY131_28510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY131_28545	COG1484	DNA-dependent DNA replication
FY131_28550	COG4584	PFAM Integrase catalytic
FY131_28555	COG2070	2-Nitropropane dioxygenase
FY131_28565	COG0604	alcohol dehydrogenase
FY131_28565	COG3321	synthase
FY131_28565	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_28570	COG0583	DNA-binding transcription factor activity
FY131_28585	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_28625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_28635	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_28640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY131_28640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY131_28645	COG1376	ErfK ybiS ycfS ynhG family protein
FY131_28650	COG1192	Involved in chromosome partitioning
FY131_28655	COG1475	DNA binding
FY131_28660	COG0640	Transcriptional regulator
FY131_28690	COG4644	lycopene metabolic process
FY131_28695	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_28725	COG5489	Protein of unknown function (DUF736)
FY131_28735	COG3831	ATPase activity
FY131_28745	COG3505	Type IV secretory pathway VirD4
FY131_28760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY131_28765	COG4959	Type IV secretory pathway protease TraF
FY131_28770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY131_28815	COG2948	multi-organism process
FY131_28825	COG3504	Conjugal transfer protein
FY131_28830	COG3701	Conjugal transfer protein
FY131_28835	COG3846	protein secretion by the type IV secretion system
FY131_28845	COG5314	conjugation
FY131_28850	COG3451	type IV secretory pathway VirB4
FY131_28855	COG5268	conjugation
FY131_28860	COG3838	Conjugal transfer protein Trbc
FY131_28865	COG4962	Type ii secretion system protein e
FY131_28920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY131_28935	COG0469	pyruvate kinase activity
FY131_28945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY131_28945	COG0574	Belongs to the PEP-utilizing enzyme family
FY131_28955	COG1028	Short-chain dehydrogenase reductase Sdr
FY131_28970	COG1619	proteins homologs of microcin C7 resistance protein MccF
FY131_28980	COG2226	methyltransferase
FY131_29000	COG0495	leucyl-tRNA aminoacylation
FY131_29015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_29025	COG1132	(ABC) transporter
FY131_29055	COG1475	DNA binding
FY131_29115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY131_29125	COG3093	addiction module antidote protein HigA
FY131_29130	COG4644	lycopene metabolic process
FY131_29135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_29145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_29180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY131_29230	COG1192	Involved in chromosome partitioning