locus-tag	class	description
AVCG412_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVCG412_00010	COG0697	spore germination
AVCG412_00020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVCG412_00025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVCG412_00035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVCG412_00040	COG1420	regulation of RNA biosynthetic process
AVCG412_00045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVCG412_00050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVCG412_00055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AVCG412_00065	COG1137	ATPase activity
AVCG412_00070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AVCG412_00080	COG0776	regulation of translation
AVCG412_00090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVCG412_00090	COG0116	Belongs to the methyltransferase superfamily
AVCG412_00095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVCG412_00100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVCG412_00115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVCG412_00120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVCG412_00130	COG0346	lactoylglutathione lyase activity
AVCG412_00135	COG0180	Tryptophanyl-tRNA synthetase
AVCG412_00145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AVCG412_00150	COG1214	PFAM Peptidase M22, glycoprotease
AVCG412_00170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVCG412_00175	COG1702	phosphate starvation-inducible protein PhoH
AVCG412_00180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVCG412_00185	COG4535	Mg2 and Co2 transporter CorC
AVCG412_00190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVCG412_00195	COG1396	sequence-specific DNA binding
AVCG412_00200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVCG412_00205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVCG412_00215	COG0071	Belongs to the small heat shock protein (HSP20) family
AVCG412_00235	COG0840	transmembrane signaling receptor activity
AVCG412_00245	COG2205	protein histidine kinase activity
AVCG412_00250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVCG412_00255	COG0594	ribonuclease P activity
AVCG412_00260	COG0706	membrane insertase activity
AVCG412_00265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVCG412_00270	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AVCG412_00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVCG412_00290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG412_00310	COG2171	N-acyltransferase activity
AVCG412_00315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG412_00340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVCG412_00345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVCG412_00355	COG0745	RESPONSE REGULATOR receiver
AVCG412_00360	COG0704	Plays a role in the regulation of phosphate uptake
AVCG412_00365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVCG412_00375	COG0573	inorganic phosphate transmembrane transporter activity
AVCG412_00385	COG5002	protein histidine kinase activity
AVCG412_00390	COG2326	polyphosphate kinase activity
AVCG412_00415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVCG412_00420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVCG412_00420	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVCG412_00430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVCG412_00450	COG0427	acetyl-CoA hydrolase
AVCG412_00460	COG3938	Belongs to the proline racemase family
AVCG412_00465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG412_00470	COG0745	RESPONSE REGULATOR receiver
AVCG412_00490	COG0418	dihydroorotase activity
AVCG412_00495	COG3706	GGDEF domain
AVCG412_00500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVCG412_00515	COG0166	Belongs to the GPI family
AVCG412_00520	COG0318	PFAM AMP-dependent synthetase and ligase
AVCG412_00535	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_00545	COG0101	tRNA pseudouridine synthase activity
AVCG412_00550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVCG412_00555	COG0242	peptide deformylase activity
AVCG412_00560	COG2967	ApaG domain
AVCG412_00570	COG0717	Belongs to the dCTP deaminase family
AVCG412_00630	COG0250	Participates in transcription elongation, termination and antitermination
AVCG412_00690	COG1450	Type ii and iii secretion system protein
AVCG412_00700	COG5489	Protein of unknown function (DUF736)
AVCG412_00705	COG4974	Belongs to the 'phage' integrase family
AVCG412_00710	COG0582	viral genome integration into host DNA
AVCG412_00715	COG4974	Belongs to the 'phage' integrase family
AVCG412_00720	COG5489	Protein of unknown function (DUF736)
AVCG412_00735	COG2165	general secretion pathway protein
AVCG412_00760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AVCG412_00795	COG4372	Transposase
AVCG412_00820	COG1216	Glycosyl transferase, family 2
AVCG412_00820	COG0438	transferase activity, transferring glycosyl groups
AVCG412_00825	COG1216	Glycosyl transferase, family 2
AVCG412_00825	COG0438	transferase activity, transferring glycosyl groups
AVCG412_00860	COG2963	transposase activity
AVCG412_00870	COG4372	Transposase
AVCG412_00905	COG2801	Transposase and inactivated derivatives
AVCG412_00935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_00965	COG0167	dihydroorotate dehydrogenase activity
AVCG412_00995	COG0697	spore germination
AVCG412_01015	COG1024	Enoyl-CoA hydratase
AVCG412_01015	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVCG412_01020	COG0183	Belongs to the thiolase family
AVCG412_01025	COG1960	acyl-CoA dehydrogenase activity
AVCG412_01045	COG1785	Belongs to the alkaline phosphatase family
AVCG412_01055	COG1136	(ABC) transporter
AVCG412_01070	COG4251	negative regulation of phosphorylation
AVCG412_01070	COG5001	Diguanylate cyclase
AVCG412_01070	COG3706	GGDEF domain
AVCG412_01070	COG2203	Gaf domain
AVCG412_01075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVCG412_01085	COG1201	RNA secondary structure unwinding
AVCG412_01105	COG1047	Peptidyl-prolyl cis-trans
AVCG412_01110	COG2198	Histidine kinase
AVCG412_01110	COG0784	Response regulator, receiver
AVCG412_01110	COG2205	protein histidine kinase activity
AVCG412_01115	COG1970	mechanosensitive ion channel activity
AVCG412_01120	COG0436	Aminotransferase
AVCG412_01130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVCG412_01150	COG1216	Glycosyl transferase, family 2
AVCG412_01160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG412_01175	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVCG412_01180	COG0424	maF-like protein
AVCG412_01185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVCG412_01195	COG5328	Belongs to the UPF0262 family
AVCG412_01200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVCG412_01210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVCG412_01250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AVCG412_01250	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AVCG412_01260	COG2942	2-epimerase
AVCG412_01265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AVCG412_01270	COG2963	transposase activity
AVCG412_01280	COG4372	Transposase
AVCG412_01285	COG0488	(ABC) transporter
AVCG412_01310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVCG412_01315	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVCG412_01320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVCG412_01325	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVCG412_01330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVCG412_01335	COG4786	Flagellar basal body rod
AVCG412_01340	COG1157	protein secretion by the type III secretion system
AVCG412_01350	COG1815	bacterial-type flagellum-dependent cell motility
AVCG412_01355	COG1558	bacterial-type flagellum-dependent cell motility
AVCG412_01360	COG1677	Flagellar hook-basal body complex protein FliE
AVCG412_01365	COG4786	Flagellar basal body rod
AVCG412_01370	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AVCG412_01375	COG1706	bacterial-type flagellum-dependent cell motility
AVCG412_01385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVCG412_01395	COG1338	Plays a role in the flagellum-specific transport system
AVCG412_01400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_01405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_01410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_01415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_01420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_01430	COG1360	Flagellar Motor Protein
AVCG412_01455	COG1749	Flagellar hook protein flgE
AVCG412_01475	COG5443	negative regulation of bacterial-type flagellum assembly
AVCG412_01480	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVCG412_01485	COG4794	Type iii secretion
AVCG412_01490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVCG412_01525	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVCG412_01530	COG1609	Transcriptional regulator
AVCG412_01535	COG1653	transport
AVCG412_01540	COG1175	transmembrane transport
AVCG412_01545	COG0395	ABC-type sugar transport system, permease component
AVCG412_01550	COG0366	Alpha amylase catalytic
AVCG412_01555	COG3842	ATPase activity
AVCG412_01570	COG3493	citrate carrier protein
AVCG412_01590	COG0129	dihydroxy-acid dehydratase activity
AVCG412_01595	COG0363	glucosamine-6-phosphate deaminase activity
AVCG412_01600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVCG412_01610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_01620	COG2081	HI0933 family
AVCG412_01635	COG0840	transmembrane signaling receptor activity
AVCG412_01635	COG2972	Histidine kinase
AVCG412_01660	COG2224	Isocitrate lyase
AVCG412_01680	COG3842	ATPase activity
AVCG412_01685	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_01690	COG1177	transmembrane transport
AVCG412_01700	COG2205	protein histidine kinase activity
AVCG412_01750	COG1959	2 iron, 2 sulfur cluster binding
AVCG412_01755	COG3265	gluconokinase activity
AVCG412_01760	COG2134	cdp-diacylglycerol pyrophosphatase
AVCG412_01770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_01775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVCG412_01795	COG0579	oxidoreductase
AVCG412_01815	COG2186	Transcriptional regulator
AVCG412_01825	COG0765	amino acid transport
AVCG412_01835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVCG412_01845	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_01850	COG1177	transmembrane transport
AVCG412_01860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG412_01865	COG0514	ATP-dependent DNA helicase (RecQ)
AVCG412_01935	COG0582	viral genome integration into host DNA
AVCG412_01945	COG0248	Ppx GppA phosphatase
AVCG412_01950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVCG412_01960	COG5001	Diguanylate cyclase
AVCG412_01960	COG3300	MHYT domain
AVCG412_01965	COG0784	Response regulator, receiver
AVCG412_01965	COG2198	Histidine kinase
AVCG412_01965	COG5002	protein histidine kinase activity
AVCG412_01970	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVCG412_01980	COG1663	tetraacyldisaccharide 4'-kinase activity
AVCG412_01990	COG1519	Transferase
AVCG412_02005	COG0312	modulator of DNA gyrase
AVCG412_02010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVCG412_02010	COG0475	glutathione-regulated potassium exporter activity
AVCG412_02020	COG0742	ribosomal rna small subunit methyltransferase
AVCG412_02025	COG1187	pseudouridine synthase activity
AVCG412_02030	COG0590	tRNA wobble adenosine to inosine editing
AVCG412_02040	COG0477	Major facilitator Superfamily
AVCG412_02050	COG3386	PFAM SMP-30 Gluconolaconase
AVCG412_02055	COG2771	luxR family
AVCG412_02080	COG3158	transport of potassium into the cell
AVCG412_02090	COG0356	it plays a direct role in the translocation of protons across the membrane
AVCG412_02100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVCG412_02105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVCG412_02110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVCG412_02125	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVCG412_02130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVCG412_02140	COG0142	geranyltranstransferase activity
AVCG412_02150	COG4106	trans-aconitate 2-methyltransferase activity
AVCG412_02170	COG0752	glycyl-tRNA synthetase alpha subunit
AVCG412_02180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVCG412_02190	COG0751	glycine-tRNA ligase activity
AVCG412_02195	COG1683	Conserved Protein
AVCG412_02200	COG0840	transmembrane signaling receptor activity
AVCG412_02200	COG0840	transmembrane signaling receptor activity
AVCG412_02210	COG0151	Belongs to the GarS family
AVCG412_02220	COG2183	response to ionizing radiation
AVCG412_02225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG412_02230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVCG412_02255	COG0725	ABC transporter, periplasmic molybdate-binding protein
AVCG412_02260	COG4149	molybdate abc transporter
AVCG412_02265	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVCG412_02270	COG3585	molybdate ion transport
AVCG412_02270	COG2005	Transcriptional regulator
AVCG412_02280	COG0009	L-threonylcarbamoyladenylate synthase
AVCG412_02290	COG0840	transmembrane signaling receptor activity
AVCG412_02290	COG2972	Histidine kinase
AVCG412_02310	COG4638	Rieske (2fe-2S)
AVCG412_02335	COG1960	acyl-CoA dehydrogenase activity
AVCG412_02340	COG1024	Enoyl-CoA hydratase
AVCG412_02355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVCG412_02360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AVCG412_02365	COG0840	transmembrane signaling receptor activity
AVCG412_02370	COG0840	transmembrane signaling receptor activity
AVCG412_02375	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVCG412_02380	COG1722	exodeoxyribonuclease VII activity
AVCG412_02385	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVCG412_02400	COG1268	BioY protein
AVCG412_02405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVCG412_02410	COG1122	ATPase activity
AVCG412_02420	COG3214	Protein conserved in bacteria
AVCG412_02430	COG1522	sequence-specific DNA binding
AVCG412_02460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVCG412_02460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVCG412_02465	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVCG412_02470	COG3300	MHYT domain
AVCG412_02470	COG5001	Diguanylate cyclase
AVCG412_02485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVCG412_02490	COG0484	heat shock protein binding
AVCG412_02500	COG0259	pyridoxamine-phosphate oxidase activity
AVCG412_02510	COG2814	Major facilitator Superfamily
AVCG412_02520	COG1686	Belongs to the peptidase S11 family
AVCG412_02535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG412_02545	COG0312	modulator of DNA gyrase
AVCG412_02560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVCG412_02565	COG0109	protoheme IX farnesyltransferase activity
AVCG412_02575	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVCG412_02590	COG3346	SURF1 family
AVCG412_02600	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVCG412_02610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVCG412_02615	COG0328	RNA-DNA hybrid ribonuclease activity
AVCG412_02625	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVCG412_02640	COG0678	peroxiredoxin activity
AVCG412_02640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVCG412_02650	COG1678	Uncharacterized ACR, COG1678
AVCG412_02660	COG0640	Transcriptional regulator
AVCG412_02665	COG5001	Diguanylate cyclase
AVCG412_02670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVCG412_02675	COG0612	Peptidase, M16
AVCG412_02690	COG1597	lipid kinase activity
AVCG412_02695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG412_02710	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AVCG412_02740	COG1194	a g-specific adenine glycosylase
AVCG412_02755	COG1196	nuclear chromosome segregation
AVCG412_02775	COG2814	Major facilitator Superfamily
AVCG412_02790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVCG412_02790	COG0574	Belongs to the PEP-utilizing enzyme family
AVCG412_02825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_02845	COG0840	transmembrane signaling receptor activity
AVCG412_02850	COG0175	sulfate reduction
AVCG412_02855	COG0175	sulfate reduction
AVCG412_02860	COG2895	sulfate adenylyltransferase (ATP) activity
AVCG412_02870	COG1609	Transcriptional regulator
AVCG412_02880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG412_02890	COG0693	protein deglycase activity
AVCG412_02905	COG0038	chloride channel
AVCG412_02915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_02930	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AVCG412_02935	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AVCG412_02945	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_02950	COG0625	glutathione transferase activity
AVCG412_02955	COG3119	arylsulfatase activity
AVCG412_02960	COG1309	transcriptional regulator
AVCG412_02965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVCG412_02970	COG0604	alcohol dehydrogenase
AVCG412_02970	COG3321	synthase
AVCG412_02970	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_02995	COG1349	DNA-binding transcription factor activity
AVCG412_03045	COG0477	Major facilitator Superfamily
AVCG412_03055	COG0778	Nitroreductase
AVCG412_03070	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG412_03070	COG1388	LysM domain
AVCG412_03075	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG412_03080	COG1846	Transcriptional regulator
AVCG412_03085	COG1764	response to oxidative stress
AVCG412_03105	COG0784	Response regulator, receiver
AVCG412_03105	COG4191	Histidine kinase
AVCG412_03110	COG3265	gluconokinase activity
AVCG412_03120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVCG412_03125	COG0840	transmembrane signaling receptor activity
AVCG412_03130	COG0840	transmembrane signaling receptor activity
AVCG412_03140	COG0433	COG0433 Predicted ATPase
AVCG412_03155	COG0840	transmembrane signaling receptor activity
AVCG412_03160	COG1968	undecaprenyl-diphosphatase activity
AVCG412_03170	COG4214	carbohydrate transport
AVCG412_03175	COG4213	ABC transporter substrate-binding protein
AVCG412_03180	COG1940	carbohydrate kinase activity
AVCG412_03180	COG1846	Transcriptional regulator
AVCG412_03200	COG1120	ATPase activity
AVCG412_03205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG412_03220	COG2226	methyltransferase
AVCG412_03230	COG2814	Major facilitator Superfamily
AVCG412_03235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG412_03235	COG3320	Male sterility
AVCG412_03250	COG2010	Cytochrome c
AVCG412_03270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVCG412_03275	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AVCG412_03280	COG1733	regulation of RNA biosynthetic process
AVCG412_03290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVCG412_03300	COG3447	MASE1 domain protein
AVCG412_03300	COG5001	Diguanylate cyclase
AVCG412_03300	COG5002	protein histidine kinase activity
AVCG412_03305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG412_03320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVCG412_03350	COG2514	catechol 2,3-dioxygenase activity
AVCG412_03365	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AVCG412_03370	COG1272	protein, Hemolysin III
AVCG412_03375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG412_03395	COG4957	zinc ion binding
AVCG412_03400	COG1320	monovalent cation:proton antiporter activity
AVCG412_03405	COG2212	antiporter activity
AVCG412_03410	COG1863	multisubunit Na H antiporter MnhE subunit
AVCG412_03415	COG0651	ATP synthesis coupled electron transport
AVCG412_03420	COG1006	Multisubunit Na H antiporter MnhC subunit
AVCG412_03425	COG2111	Na H antiporter
AVCG412_03430	COG2111	Na H antiporter
AVCG412_03430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVCG412_03435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVCG412_03455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_03460	COG1136	(ABC) transporter
AVCG412_03460	COG0577	efflux transmembrane transporter activity
AVCG412_03470	COG1309	transcriptional regulator
AVCG412_03475	COG2166	iron-sulfur cluster assembly
AVCG412_03485	COG2205	protein histidine kinase activity
AVCG412_03500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG412_03510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_03565	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVCG412_03570	COG2983	Belongs to the UPF0260 family
AVCG412_03595	COG0789	Transcriptional regulator
AVCG412_03620	COG4695	Portal protein
AVCG412_03720	COG4520	surface antigen
AVCG412_03725	COG4235	cytochrome complex assembly
AVCG412_03730	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AVCG412_03735	COG1138	Cytochrome C-type biogenesis protein
AVCG412_03740	COG3088	subunit of a heme lyase
AVCG412_03750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVCG412_03755	COG0745	RESPONSE REGULATOR receiver
AVCG412_03760	COG2205	protein histidine kinase activity
AVCG412_03765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVCG412_03770	COG2202	Pas domain
AVCG412_03770	COG2205	protein histidine kinase activity
AVCG412_03775	COG0308	aminopeptidase N
AVCG412_03780	COG0840	transmembrane signaling receptor activity
AVCG412_03780	COG3290	protein histidine kinase activity
AVCG412_03815	COG0443	Heat shock 70 kDa protein
AVCG412_03830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_03845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG412_03850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG412_03855	COG2239	Acts as a magnesium transporter
AVCG412_03860	COG2814	Major facilitator Superfamily
AVCG412_03870	COG4172	Belongs to the ABC transporter superfamily
AVCG412_03875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_03880	COG0601	transmembrane transport
AVCG412_03885	COG4166	transmembrane transport
AVCG412_03890	COG0174	glutamine synthetase
AVCG412_03905	COG1695	Transcriptional regulator
AVCG412_03910	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVCG412_03915	COG0463	Glycosyl transferase, family 2
AVCG412_03925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVCG412_03935	COG0625	glutathione transferase activity
AVCG412_03950	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVCG412_03990	COG0741	lytic transglycosylase activity
AVCG412_03995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG412_04000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVCG412_04010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVCG412_04010	COG2169	Transcriptional regulator
AVCG412_04015	COG0840	transmembrane signaling receptor activity
AVCG412_04025	COG1758	RNA polymerase activity
AVCG412_04040	COG0681	Belongs to the peptidase S26 family
AVCG412_04045	COG0571	ribonuclease III activity
AVCG412_04050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVCG412_04055	COG3180	Ammonia monooxygenase
AVCG412_04060	COG1381	Involved in DNA repair and RecF pathway recombination
AVCG412_04075	COG1418	mRNA catabolic process
AVCG412_04090	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVCG412_04115	COG1051	belongs to the nudix hydrolase family
AVCG412_04130	COG1183	phosphatidylcholine synthase activity
AVCG412_04135	COG0688	phosphatidylethanolamine metabolic process
AVCG412_04140	COG5265	(ABC) transporter
AVCG412_04145	COG1652	LysM domain
AVCG412_04145	COG2823	Periplasmic or secreted lipoprotein
AVCG412_04160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVCG412_04200	COG0215	cysteine-tRNA ligase activity
AVCG412_04210	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AVCG412_04215	COG1088	dTDP-glucose 4,6-dehydratase activity
AVCG412_04220	COG1091	dTDP-4-dehydrorhamnose reductase activity
AVCG412_04225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVCG412_04240	COG4221	oxidoreductase activity
AVCG412_04245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVCG412_04250	COG1286	toxin biosynthetic process
AVCG412_04255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AVCG412_04260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVCG412_04275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVCG412_04285	COG0765	amino acid transport
AVCG412_04290	COG0765	amino acid transport
AVCG412_04300	COG0305	Participates in initiation and elongation during chromosome replication
AVCG412_04305	COG0359	binds to the 23S rRNA
AVCG412_04315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVCG412_04320	COG0360	Binds together with S18 to 16S ribosomal RNA
AVCG412_04340	COG0667	Aldo Keto reductase
AVCG412_04345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVCG412_04355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG412_04360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVCG412_04365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVCG412_04370	COG1561	YicC-like family, N-terminal region
AVCG412_04375	COG0194	GDP metabolic process
AVCG412_04380	COG0500	methyltransferase
AVCG412_04385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVCG412_04390	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVCG412_04400	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVCG412_04415	COG0671	phosphoesterase, PA-phosphatase related
AVCG412_04420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVCG412_04430	COG0840	transmembrane signaling receptor activity
AVCG412_04430	COG2972	Histidine kinase
AVCG412_04435	COG0488	(ABC) transporter
AVCG412_04445	COG0105	UTP biosynthetic process
AVCG412_04450	COG0314	molybdopterin synthase activity
AVCG412_04460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVCG412_04465	COG0322	excinuclease ABC activity
AVCG412_04470	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_04480	COG0625	glutathione transferase activity
AVCG412_04485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVCG412_04490	COG0243	molybdopterin cofactor binding
AVCG412_04500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG412_04500	COG3453	Protein conserved in bacteria
AVCG412_04505	COG0640	Transcriptional regulator
AVCG412_04515	COG2391	methyltransferase activity
AVCG412_04525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVCG412_04530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVCG412_04535	COG0628	permease
AVCG412_04545	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVCG412_04550	COG0248	Ppx GppA phosphatase
AVCG412_04555	COG1321	iron dependent repressor
AVCG412_04560	COG1914	H( )-stimulated, divalent metal cation uptake system
AVCG412_04580	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AVCG412_04585	COG2132	Multicopper oxidase
AVCG412_04595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVCG412_04610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AVCG412_04615	COG3300	MHYT domain
AVCG412_04615	COG5001	Diguanylate cyclase
AVCG412_04625	COG2203	Gaf domain
AVCG412_04625	COG2199	diguanylate cyclase activity
AVCG412_04625	COG2200	EAL domain
AVCG412_04630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVCG412_04640	COG0113	porphobilinogen synthase activity
AVCG412_04660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVCG412_04665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVCG412_04670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVCG412_04670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVCG412_04690	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVCG412_04695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVCG412_04700	COG2814	Major facilitator Superfamily
AVCG412_04705	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AVCG412_04725	COG0416	fatty acid biosynthetic process
AVCG412_04730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVCG412_04735	COG0776	regulation of translation
AVCG412_04815	COG1612	heme a metabolic process
AVCG412_04820	COG3384	dioxygenase
AVCG412_04830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVCG412_04835	COG0010	Belongs to the arginase family
AVCG412_04850	COG2329	Antibiotic biosynthesis monooxygenase
AVCG412_04855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVCG412_04860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVCG412_04865	COG1832	CoA-binding protein
AVCG412_04875	COG1832	CoA-binding protein
AVCG412_04885	COG1408	metallophosphoesterase
AVCG412_04910	COG0740	serine-type endopeptidase activity
AVCG412_04915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVCG412_04920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVCG412_04950	COG1024	Enoyl-CoA hydratase
AVCG412_04970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG412_04975	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG412_04980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG412_04985	COG0649	NAD binding
AVCG412_04995	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AVCG412_05000	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AVCG412_05015	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVCG412_05020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG412_05030	COG0713	ATP synthesis coupled electron transport
AVCG412_05045	COG1007	ATP synthesis coupled electron transport
AVCG412_05060	COG0346	lactoylglutathione lyase activity
AVCG412_05065	COG0251	oxidation-reduction process
AVCG412_05080	COG0442	prolyl-tRNA aminoacylation
AVCG412_05090	COG1136	(ABC) transporter
AVCG412_05105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVCG412_05120	COG0784	Response regulator, receiver
AVCG412_05130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVCG412_05135	COG0477	Major facilitator Superfamily
AVCG412_05145	COG0557	exoribonuclease II activity
AVCG412_05150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVCG412_05160	COG0758	DNA mediated transformation
AVCG412_05165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVCG412_05175	COG0540	Belongs to the ATCase OTCase family
AVCG412_05180	COG1960	acyl-CoA dehydrogenase activity
AVCG412_05200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVCG412_05205	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVCG412_05210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVCG412_05215	COG0154	amidase activity
AVCG412_05230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVCG412_05235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG412_05235	COG3952	Lipid A Biosynthesis
AVCG412_05240	COG0463	Glycosyl transferase, family 2
AVCG412_05250	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVCG412_05270	COG4765	Protein conserved in bacteria
AVCG412_05275	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVCG412_05285	COG0511	ligase activity, forming carbon-carbon bonds
AVCG412_05290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVCG412_05295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVCG412_05300	COG0436	Aminotransferase
AVCG412_05310	COG1530	ribonuclease E activity
AVCG412_05320	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVCG412_05325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVCG412_05335	COG0284	orotidine-5'-phosphate decarboxylase activity
AVCG412_05345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVCG412_05365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVCG412_05380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVCG412_05405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVCG412_05415	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVCG412_05420	COG0081	regulation of translation
AVCG412_05425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVCG412_05430	COG0222	ribosome binding
AVCG412_05435	COG0085	RNA polymerase activity
AVCG412_05440	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVCG412_05455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVCG412_05460	COG0049	tRNA binding
AVCG412_05465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVCG412_05470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVCG412_05475	COG0051	transcription antitermination factor activity, RNA binding
AVCG412_05480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVCG412_05485	COG0088	Forms part of the polypeptide exit tunnel
AVCG412_05490	COG0089	rRNA binding
AVCG412_05495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVCG412_05500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVCG412_05505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVCG412_05510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVCG412_05515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVCG412_05520	COG0255	Belongs to the universal ribosomal protein uL29 family
AVCG412_05525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVCG412_05530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVCG412_05535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVCG412_05540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVCG412_05545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVCG412_05550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVCG412_05555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVCG412_05560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVCG412_05565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVCG412_05570	COG1841	ribosomal large subunit assembly
AVCG412_05575	COG0200	Binds to the 23S rRNA
AVCG412_05580	COG0201	protein transport
AVCG412_05585	COG0563	adenylate kinase activity
AVCG412_05590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVCG412_05595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVCG412_05600	COG0202	RNA polymerase activity
AVCG412_05605	COG0203	ribosomal protein L17
AVCG412_05615	COG3739	integral membrane protein
AVCG412_05625	COG2897	thiosulfate sulfurtransferase activity
AVCG412_05630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVCG412_05635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVCG412_05640	COG0415	Belongs to the DNA photolyase family
AVCG412_05650	COG0739	heme binding
AVCG412_05655	COG2833	Protein of unknown function (DUF455)
AVCG412_05660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVCG412_05685	COG0280	phosphate acetyltransferase
AVCG412_05685	COG0281	malic enzyme
AVCG412_05695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVCG412_05700	COG1127	ABC transporter
AVCG412_05710	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVCG412_05710	COG3218	ABC-type transport auxiliary lipoprotein component
AVCG412_05715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVCG412_05735	COG0047	phosphoribosylformylglycinamidine synthase activity
AVCG412_05740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVCG412_05745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVCG412_05760	COG3706	GGDEF domain
AVCG412_05770	COG0538	isocitrate dehydrogenase activity
AVCG412_05775	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVCG412_05780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVCG412_05790	COG1253	flavin adenine dinucleotide binding
AVCG412_05800	COG0657	acetylesterase activity
AVCG412_05800	COG2755	lipolytic protein G-D-S-L family
AVCG412_05805	COG2195	Cleaves the N-terminal amino acid of tripeptides
AVCG412_05820	COG0861	Integral membrane protein TerC family
AVCG412_05825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVCG412_05830	COG2066	Belongs to the glutaminase family
AVCG412_05840	COG0037	tRNA processing
AVCG412_05845	COG0483	inositol monophosphate 1-phosphatase activity
AVCG412_05850	COG0483	inositol monophosphate 1-phosphatase activity
AVCG412_05855	COG2814	Major facilitator Superfamily
AVCG412_05860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVCG412_05875	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVCG412_05880	COG0484	heat shock protein binding
AVCG412_05895	COG0321	lipoyl(octanoyl) transferase activity
AVCG412_05925	COG0592	DNA-directed DNA polymerase activity
AVCG412_05995	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AVCG412_06000	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AVCG412_06030	COG0242	peptide deformylase activity
AVCG412_06040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVCG412_06045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG412_06050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVCG412_06055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVCG412_06060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVCG412_06085	COG0823	Involved in the tonB-independent uptake of proteins
AVCG412_06090	COG0778	Nitroreductase
AVCG412_06100	COG2267	carboxylic ester hydrolase activity
AVCG412_06105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVCG412_06110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVCG412_06130	COG2202	Pas domain
AVCG412_06130	COG2205	protein histidine kinase activity
AVCG412_06140	COG1573	uracil-dna glycosylase
AVCG412_06145	COG1522	sequence-specific DNA binding
AVCG412_06150	COG2084	Dehydrogenase
AVCG412_06155	COG2267	carboxylic ester hydrolase activity
AVCG412_06165	COG5425	PFAM Usg family protein
AVCG412_06190	COG1763	Mo-molybdopterin cofactor biosynthetic process
AVCG412_06195	COG0746	molybdenum cofactor guanylyltransferase activity
AVCG412_06205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVCG412_06215	COG3706	GGDEF domain
AVCG412_06230	COG0114	fumarate hydratase activity
AVCG412_06235	COG2989	Protein conserved in bacteria
AVCG412_06240	COG0546	phosphoglycolate phosphatase activity
AVCG412_06245	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVCG412_06260	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVCG412_06300	COG3706	GGDEF domain
AVCG412_06300	COG2203	Gaf domain
AVCG412_06300	COG5001	Diguanylate cyclase
AVCG412_06300	COG4251	negative regulation of phosphorylation
AVCG412_06305	COG0556	nucleotide-excision repair
AVCG412_06325	COG3161	chorismate lyase activity
AVCG412_06335	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVCG412_06340	COG0148	phosphopyruvate hydratase activity
AVCG412_06350	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVCG412_06355	COG0022	dehydrogenase e1 component
AVCG412_06355	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVCG412_06360	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVCG412_06375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVCG412_06385	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVCG412_06390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVCG412_06400	COG0477	Major facilitator Superfamily
AVCG412_06405	COG2867	negative regulation of translational initiation
AVCG412_06410	COG1546	Belongs to the CinA family
AVCG412_06410	COG1058	Belongs to the CinA family
AVCG412_06415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVCG412_06415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVCG412_06425	COG3852	Histidine kinase
AVCG412_06430	COG2204	response regulator
AVCG412_06435	COG5000	phosphorelay sensor kinase activity
AVCG412_06440	COG2204	response regulator
AVCG412_06445	COG1923	regulation of RNA biosynthetic process
AVCG412_06450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVCG412_06460	COG3956	TIGRFAM MazG family protein
AVCG412_06470	COG1648	precorrin-2 dehydrogenase activity
AVCG412_06470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVCG412_06495	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_06505	COG1686	Belongs to the peptidase S11 family
AVCG412_06510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVCG412_06520	COG0730	response to heat
AVCG412_06525	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVCG412_06530	COG0084	hydrolase, TatD family'
AVCG412_06535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVCG412_06535	COG0321	lipoyl(octanoyl) transferase activity
AVCG412_06550	COG0785	Cytochrome C biogenesis protein
AVCG412_06555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG412_06560	COG1183	phosphatidylcholine synthase activity
AVCG412_06565	COG3845	ABC transporter
AVCG412_06570	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVCG412_06575	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG412_06585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVCG412_06590	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVCG412_06610	COG1177	transmembrane transport
AVCG412_06615	COG4149	molybdate abc transporter
AVCG412_06620	COG3842	ATPase activity
AVCG412_06635	COG0523	cobalamin synthesis protein
AVCG412_06645	COG1121	(ABC) transporter
AVCG412_06650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVCG412_06655	COG0735	belongs to the Fur family
AVCG412_06675	COG1686	Belongs to the peptidase S11 family
AVCG412_06710	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVCG412_06715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVCG412_06720	COG0302	gtp cyclohydrolase
AVCG412_06730	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVCG412_06740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVCG412_06755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVCG412_06760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVCG412_06805	COG0187	DNA topoisomerase II activity
AVCG412_06820	COG0149	triose-phosphate isomerase activity
AVCG412_06830	COG0504	CTP synthase activity
AVCG412_06850	COG0633	Ferredoxin
AVCG412_06860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVCG412_06880	COG3768	UPF0283 membrane protein
AVCG412_06885	COG3106	COG3106 Predicted ATPase
AVCG412_06920	COG2080	2 iron, 2 sulfur cluster binding
AVCG412_06925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVCG412_06930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG412_06935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AVCG412_06945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVCG412_06955	COG0343	queuine tRNA-ribosyltransferase activity
AVCG412_06960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVCG412_06975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVCG412_06990	COG2151	metal-sulfur cluster biosynthetic enzyme
AVCG412_06995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVCG412_07000	COG0719	Fe-S assembly protein
AVCG412_07005	COG0396	ATPase activity
AVCG412_07015	COG0719	Fe-S assembly protein
AVCG412_07020	COG1104	cysteine desulfurase activity
AVCG412_07025	COG2945	thiolester hydrolase activity
AVCG412_07030	COG1280	lysine exporter protein (LysE YggA)
AVCG412_07035	COG0513	Belongs to the DEAD box helicase family
AVCG412_07060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG412_07085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVCG412_07090	COG3385	transposase activity
AVCG412_07105	COG0129	dihydroxy-acid dehydratase activity
AVCG412_07110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVCG412_07115	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AVCG412_07130	COG3507	Belongs to the glycosyl hydrolase 43 family
AVCG412_07135	COG0667	Aldo Keto reductase
AVCG412_07155	COG3842	ATPase activity
AVCG412_07160	COG0395	ABC-type sugar transport system, permease component
AVCG412_07165	COG1175	transmembrane transport
AVCG412_07170	COG1653	transport
AVCG412_07185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVCG412_07220	COG2095	MarC family integral membrane protein
AVCG412_07230	COG0629	single-stranded DNA binding
AVCG412_07235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVCG412_07250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVCG412_07250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVCG412_07255	COG0347	Belongs to the P(II) protein family
AVCG412_07260	COG0174	glutamine synthetase
AVCG412_07285	COG0697	spore germination
AVCG412_07295	COG1280	lysine exporter protein (LysE YggA)
AVCG412_07300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVCG412_07310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVCG412_07340	COG1278	Cold shock
AVCG412_07345	COG0346	lactoylglutathione lyase activity
AVCG412_07370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVCG412_07380	COG0436	Aminotransferase
AVCG412_07390	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVCG412_07395	COG1489	DNA binding
AVCG412_07400	COG2855	membrane
AVCG412_07405	COG0583	DNA-binding transcription factor activity
AVCG412_07410	COG0024	Methionine aminopeptidase
AVCG412_07415	COG2003	Belongs to the UPF0758 family
AVCG412_07430	COG0477	Major facilitator Superfamily
AVCG412_07445	COG0546	phosphoglycolate phosphatase activity
AVCG412_07450	COG0564	pseudouridine synthase activity
AVCG412_07455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVCG412_07475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG412_07480	COG0509	glycine decarboxylation via glycine cleavage system
AVCG412_07485	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVCG412_07485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVCG412_07500	COG0436	Aminotransferase
AVCG412_07510	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVCG412_07515	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVCG412_07545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVCG412_07550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVCG412_07565	COG0252	asparaginase activity
AVCG412_07575	COG0737	Belongs to the 5'-nucleotidase family
AVCG412_07585	COG0463	Glycosyl transferase, family 2
AVCG412_07590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVCG412_07605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVCG412_07610	COG3665	Urea carboxylase-associated protein
AVCG412_07620	COG4770	biotin carboxylase activity
AVCG412_07640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVCG412_07645	COG2153	protein acetylation
AVCG412_07650	COG1671	Belongs to the UPF0178 family
AVCG412_07660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVCG412_07665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG412_07675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG412_07680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVCG412_07685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG412_07690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVCG412_07695	COG0750	zinc metalloprotease
AVCG412_07705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVCG412_07710	COG0233	cytoplasmic translational termination
AVCG412_07715	COG0528	UMP kinase activity
AVCG412_07720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVCG412_07725	COG0052	Belongs to the universal ribosomal protein uS2 family
AVCG412_07750	COG0537	adenosine 5'-monophosphoramidase activity
AVCG412_07770	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVCG412_07795	COG2267	carboxylic ester hydrolase activity
AVCG412_07815	COG0626	cystathionine gamma-synthase activity
AVCG412_07820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_07825	COG4597	amino acid ABC transporter
AVCG412_07830	COG0765	amino acid transport
AVCG412_07835	COG1126	abc transporter atp-binding protein
AVCG412_07840	COG0154	amidase activity
AVCG412_07845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVCG412_07850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVCG412_07860	COG2313	pseudouridylate synthase activity
AVCG412_07865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVCG412_07870	COG2333	competence protein COMEC
AVCG412_07870	COG0658	competence protein
AVCG412_07875	COG0372	Belongs to the citrate synthase family
AVCG412_07885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVCG412_07890	COG0134	indole-3-glycerol-phosphate synthase activity
AVCG412_07895	COG0315	cyclic pyranopterin monophosphate synthase activity
AVCG412_07900	COG0303	'Molybdopterin
AVCG412_07905	COG0671	phosphoesterase, PA-phosphatase related
AVCG412_07910	COG1492	cobalamin metabolic process
AVCG412_07920	COG4176	ABC-type proline glycine betaine transport system permease component
AVCG412_07925	COG4175	Glycine betaine
AVCG412_07925	COG0517	IMP dehydrogenase activity
AVCG412_07970	COG0583	DNA-binding transcription factor activity
AVCG412_08000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG412_08015	COG0681	Belongs to the peptidase S26 family
AVCG412_08020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVCG412_08030	COG0840	transmembrane signaling receptor activity
AVCG412_08040	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AVCG412_08050	COG1546	Belongs to the CinA family
AVCG412_08050	COG1058	Belongs to the CinA family
AVCG412_08055	COG0840	transmembrane signaling receptor activity
AVCG412_08065	COG0835	chemotaxis
AVCG412_08075	COG1760	l-serine dehydratase
AVCG412_08100	COG2239	Acts as a magnesium transporter
AVCG412_08130	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AVCG412_08135	COG2099	Precorrin-6x reductase
AVCG412_08140	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVCG412_08150	COG2875	Belongs to the precorrin methyltransferase family
AVCG412_08175	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AVCG412_08225	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AVCG412_08250	COG1862	Preprotein translocase
AVCG412_08265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVCG412_08270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVCG412_08275	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVCG412_08280	COG0805	protein transport
AVCG412_08285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVCG412_08290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVCG412_08295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVCG412_08300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVCG412_08305	COG1472	Belongs to the glycosyl hydrolase 3 family
AVCG412_08315	COG0018	arginyl-trna synthetase
AVCG412_08320	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVCG412_08325	COG0316	Belongs to the HesB IscA family
AVCG412_08345	COG0525	valine-tRNA ligase activity
AVCG412_08360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVCG412_08425	COG0250	Participates in transcription elongation, termination and antitermination
AVCG412_08460	COG0842	Transport permease protein
AVCG412_08465	COG1131	(ABC) transporter
AVCG412_08475	COG0745	RESPONSE REGULATOR receiver
AVCG412_08490	COG2226	methyltransferase
AVCG412_08495	COG3264	Mechanosensitive ion channel
AVCG412_08495	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVCG412_08515	COG4558	Periplasmic binding protein
AVCG412_08520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG412_08525	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVCG412_08700	COG0629	single-stranded DNA binding
AVCG412_08735	COG0592	DNA-directed DNA polymerase activity
AVCG412_08760	COG0384	phenazine biosynthesis protein PhzF
AVCG412_08780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVCG412_08790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVCG412_08805	COG1522	sequence-specific DNA binding
AVCG412_08810	COG1794	racemase activity, acting on amino acids and derivatives
AVCG412_08815	COG1309	transcriptional regulator
AVCG412_08820	COG2814	Major facilitator Superfamily
AVCG412_08830	COG1733	regulation of RNA biosynthetic process
AVCG412_08840	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVCG412_08845	COG0789	Transcriptional regulator
AVCG412_08850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVCG412_08855	COG0656	L-ascorbic acid biosynthetic process
AVCG412_08870	COG0028	Belongs to the TPP enzyme family
AVCG412_08885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVCG412_08890	COG0560	Phosphoserine phosphatase
AVCG412_08905	COG0330	HflC and HflK could
AVCG412_08920	COG2259	Doxx family
AVCG412_08925	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVCG412_08960	COG0277	FAD linked oxidase domain protein
AVCG412_08965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVCG412_08970	COG0581	inorganic phosphate transmembrane transporter activity
AVCG412_08975	COG0573	inorganic phosphate transmembrane transporter activity
AVCG412_08980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVCG412_09000	COG4993	Dehydrogenase
AVCG412_09005	COG1335	isochorismatase
AVCG412_09010	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVCG412_09015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AVCG412_09055	COG2264	protein methyltransferase activity
AVCG412_09060	COG1999	signal sequence binding
AVCG412_09065	COG0840	transmembrane signaling receptor activity
AVCG412_09070	COG0835	chemotaxis
AVCG412_09085	COG2176	DNA-directed DNA polymerase activity
AVCG412_09095	COG0456	acetyltransferase
AVCG412_09100	COG0513	Belongs to the DEAD box helicase family
AVCG412_09135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVCG412_09145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVCG412_09155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVCG412_09165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVCG412_09170	COG0849	cell division
AVCG412_09175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVCG412_09180	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVCG412_09190	COG0477	Major facilitator Superfamily
AVCG412_09195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVCG412_09200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVCG412_09205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVCG412_09215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AVCG412_09220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVCG412_09230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVCG412_09245	COG0275	rRNA processing
AVCG412_09250	COG2001	Belongs to the MraZ family
AVCG412_09270	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVCG412_09335	COG2226	methyltransferase
AVCG412_09340	COG0840	transmembrane signaling receptor activity
AVCG412_09345	COG0840	transmembrane signaling receptor activity
AVCG412_09360	COG2267	carboxylic ester hydrolase activity
AVCG412_09365	COG0697	spore germination
AVCG412_09370	COG0028	Belongs to the TPP enzyme family
AVCG412_09375	COG0251	oxidation-reduction process
AVCG412_09390	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG412_09415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVCG412_09420	COG4149	molybdate abc transporter
AVCG412_09425	COG3842	ATPase activity
AVCG412_09440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVCG412_09450	COG1396	sequence-specific DNA binding
AVCG412_09495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVCG412_09500	COG0697	spore germination
AVCG412_09510	COG2968	Membrane
AVCG412_09605	COG4387	Mu-like prophage protein GP36
AVCG412_09615	COG4397	Mu-like prophage major head subunit gpT
AVCG412_09775	COG1475	DNA binding
AVCG412_09825	COG2226	methyltransferase
AVCG412_09860	COG2963	transposase activity
AVCG412_09870	COG4372	Transposase
AVCG412_09875	COG1192	Involved in chromosome partitioning
AVCG412_09895	COG2963	transposase activity
AVCG412_09905	COG4372	Transposase
AVCG412_09910	COG2199	diguanylate cyclase activity
AVCG412_09915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AVCG412_09925	COG1278	Cold shock
AVCG412_09960	COG0432	Pfam Uncharacterised protein family UPF0047
AVCG412_09965	COG5001	Diguanylate cyclase
AVCG412_09965	COG4251	negative regulation of phosphorylation
AVCG412_09965	COG3706	GGDEF domain
AVCG412_09965	COG2203	Gaf domain
AVCG412_09975	COG0583	DNA-binding transcription factor activity
AVCG412_09990	COG1473	amidohydrolase
AVCG412_10010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVCG412_10020	COG1268	BioY protein
AVCG412_10025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVCG412_10035	COG0505	Belongs to the CarA family
AVCG412_10040	COG0534	Mate efflux family protein
AVCG412_10045	COG0583	DNA-binding transcription factor activity
AVCG412_10050	COG0667	Aldo Keto reductase
AVCG412_10055	COG2321	neutral zinc metallopeptidase
AVCG412_10070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVCG412_10080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVCG412_10120	COG1522	sequence-specific DNA binding
AVCG412_10125	COG0492	ferredoxin-NADP+ reductase activity
AVCG412_10130	COG0583	DNA-binding transcription factor activity
AVCG412_10140	COG0640	Transcriptional regulator
AVCG412_10145	COG1902	pentaerythritol trinitrate reductase activity
AVCG412_10165	COG0387	Pfam Sodium calcium exchanger
AVCG412_10175	COG0436	Aminotransferase
AVCG412_10195	COG1278	Cold shock
AVCG412_10200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG412_10210	COG1846	Transcriptional regulator
AVCG412_10215	COG0745	RESPONSE REGULATOR receiver
AVCG412_10220	COG2205	protein histidine kinase activity
AVCG412_10225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVCG412_10245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVCG412_10260	COG0006	proline dipeptidase activity
AVCG412_10270	COG3321	synthase
AVCG412_10270	COG0604	alcohol dehydrogenase
AVCG412_10280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVCG412_10295	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_10305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVCG412_10320	COG0193	aminoacyl-tRNA hydrolase activity
AVCG412_10335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVCG412_10340	COG0012	GTP binding
AVCG412_10360	COG0386	Belongs to the glutathione peroxidase family
AVCG412_10380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVCG412_10385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVCG412_10385	COG2857	Cytochrome c1
AVCG412_10410	COG1132	(ABC) transporter
AVCG412_10420	COG1132	(ABC) transporter
AVCG412_10425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVCG412_10435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG412_10445	COG0408	coproporphyrinogen oxidase activity
AVCG412_10460	COG0617	tRNA 3'-terminal CCA addition
AVCG412_10475	COG0714	Associated with various cellular activities
AVCG412_10515	COG0435	Glutathione S-transferase
AVCG412_10530	COG0740	serine-type endopeptidase activity
AVCG412_10535	COG3135	benzoate transporter
AVCG412_10540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVCG412_10550	COG4115	mRNA cleavage
AVCG412_10590	COG0512	Glutamine amidotransferase of anthranilate synthase
AVCG412_10590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVCG412_10605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVCG412_10610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVCG412_10615	COG3416	Protein conserved in bacteria
AVCG412_10625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVCG412_10640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AVCG412_10645	COG2197	response regulator
AVCG412_10660	COG1435	thymidine kinase activity
AVCG412_10680	COG4175	Glycine betaine
AVCG412_10695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVCG412_10730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVCG412_10740	COG4115	mRNA cleavage
AVCG412_10745	COG0366	Alpha amylase catalytic
AVCG412_10755	COG1160	GTP binding
AVCG412_10775	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AVCG412_10780	COG0477	Major facilitator Superfamily
AVCG412_10790	COG0024	Methionine aminopeptidase
AVCG412_10795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_10800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVCG412_10805	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_10815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG412_10825	COG0457	Tetratricopeptide repeat
AVCG412_10830	COG0583	DNA-binding transcription factor activity
AVCG412_10840	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_10855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG412_10865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG412_10900	COG3385	transposase activity
AVCG412_10905	COG0137	argininosuccinate synthase activity
AVCG412_10930	COG2351	hydroxyisourate hydrolase activity
AVCG412_10935	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AVCG412_10940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG412_10945	COG0174	glutamine synthetase
AVCG412_10955	COG3648	Uricase
AVCG412_10955	COG3195	allantoin biosynthetic process
AVCG412_10960	COG1064	alcohol dehydrogenase
AVCG412_10975	COG3706	GGDEF domain
AVCG412_10990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_10990	COG2022	thiamine diphosphate biosynthetic process
AVCG412_10995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_10995	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVCG412_11010	COG0513	Belongs to the DEAD box helicase family
AVCG412_11025	COG1733	regulation of RNA biosynthetic process
AVCG412_11040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVCG412_11055	COG1982	Orn Lys Arg decarboxylase major
AVCG412_11170	COG2308	Evidence 4 Homologs of previously reported genes of
AVCG412_11195	COG2346	COG2346, Truncated hemoglobins
AVCG412_11215	COG0493	'glutamate synthase
AVCG412_11235	COG1309	transcriptional regulator
AVCG412_11260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG412_11265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG412_11270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG412_11290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG412_11295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVCG412_11300	COG0830	nickel cation binding
AVCG412_11305	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AVCG412_11310	COG5001	Diguanylate cyclase
AVCG412_11310	COG5002	protein histidine kinase activity
AVCG412_11335	COG0804	urea catabolic process
AVCG412_11340	COG1442	glycosyl transferase family 8
AVCG412_11345	COG3755	Protein conserved in bacteria
AVCG412_11350	COG0832	Belongs to the urease beta subunit family
AVCG412_11355	COG3813	Protein conserved in bacteria
AVCG412_11360	COG0831	urea catabolic process
AVCG412_11365	COG0829	nickel cation binding
AVCG412_11410	COG4251	negative regulation of phosphorylation
AVCG412_11420	COG0784	Response regulator, receiver
AVCG412_11420	COG2198	Histidine kinase
AVCG412_11420	COG2205	protein histidine kinase activity
AVCG412_11450	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVCG412_11455	COG2894	cell division
AVCG412_11460	COG0850	regulation of cytokinetic process
AVCG412_11510	COG2814	Major facilitator Superfamily
AVCG412_11520	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVCG412_11585	COG0564	pseudouridine synthase activity
AVCG412_11590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_11590	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVCG412_11595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVCG412_11605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVCG412_11620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVCG412_11630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVCG412_11650	COG1116	anion transmembrane transporter activity
AVCG412_11660	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_11670	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVCG412_11695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVCG412_11730	COG1175	transmembrane transport
AVCG412_11755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG412_11765	COG0482	sulfurtransferase activity
AVCG412_11775	COG4774	siderophore transport
AVCG412_11795	COG1120	ATPase activity
AVCG412_11805	COG4774	siderophore transport
AVCG412_11835	COG1294	oxidase, subunit
AVCG412_11840	COG1271	oxidase subunit
AVCG412_11845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVCG412_11870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_11875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVCG412_11880	COG0632	four-way junction helicase activity
AVCG412_11885	COG2002	toxin-antitoxin pair type II binding
AVCG412_11895	COG2255	four-way junction helicase activity
AVCG412_11900	COG1408	metallophosphoesterase
AVCG412_11905	COG0494	nUDIX hydrolase
AVCG412_11920	COG0824	Thioesterase
AVCG412_11940	COG0823	Involved in the tonB-independent uptake of proteins
AVCG412_11945	COG2885	chlorophyll binding
AVCG412_11955	COG0037	tRNA processing
AVCG412_11960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVCG412_11965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVCG412_11970	COG0217	transcriptional regulatory protein
AVCG412_12050	COG2972	Histidine kinase
AVCG412_12050	COG0840	transmembrane signaling receptor activity
AVCG412_12055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVCG412_12060	COG1692	metallophosphoesterase
AVCG412_12065	COG0126	phosphoglycerate kinase activity
AVCG412_12070	COG3588	fructose-bisphosphate aldolase
AVCG412_12075	COG0384	phenazine biosynthesis protein PhzF
AVCG412_12110	COG0254	rRNA binding
AVCG412_12115	COG1132	(ABC) transporter
AVCG412_12135	COG0483	inositol monophosphate 1-phosphatase activity
AVCG412_12145	COG0352	thiamine-phosphate diphosphorylase activity
AVCG412_12155	COG0640	Transcriptional regulator
AVCG412_12170	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVCG412_12175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVCG412_12180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVCG412_12185	COG0457	Tetratricopeptide repeat
AVCG412_12190	COG0596	Alpha beta hydrolase
AVCG412_12195	COG0469	pyruvate kinase activity
AVCG412_12215	COG3750	Belongs to the UPF0335 family
AVCG412_12235	COG0512	Glutamine amidotransferase of anthranilate synthase
AVCG412_12235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVCG412_12240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG412_12245	COG5310	Homospermidine synthase
AVCG412_12255	COG0737	Belongs to the 5'-nucleotidase family
AVCG412_12260	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVCG412_12270	COG0840	transmembrane signaling receptor activity
AVCG412_12280	COG0602	queuosine metabolic process
AVCG412_12285	COG0720	synthase
AVCG412_12290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVCG412_12295	COG0330	HflC and HflK could
AVCG412_12305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVCG412_12305	COG0517	IMP dehydrogenase activity
AVCG412_12315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVCG412_12320	COG2951	lytic endotransglycosylase activity
AVCG412_12330	COG0840	transmembrane signaling receptor activity
AVCG412_12340	COG0067	glutamate synthase
AVCG412_12340	COG0069	glutamate synthase activity
AVCG412_12340	COG0070	glutamate synthase
AVCG412_12350	COG0071	Belongs to the small heat shock protein (HSP20) family
AVCG412_12385	COG0668	transmembrane transport
AVCG412_12390	COG0662	Cupin 2, conserved barrel domain protein
AVCG412_12390	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AVCG412_12400	COG2308	Evidence 4 Homologs of previously reported genes of
AVCG412_12400	COG2307	Protein conserved in bacteria
AVCG412_12420	COG0058	SHG alpha-glucan phosphorylase activity
AVCG412_12425	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVCG412_12430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVCG412_12435	COG0297	glycogen (starch) synthase activity
AVCG412_12440	COG0033	Phosphoglucomutase
AVCG412_12465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVCG412_12480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVCG412_12485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_12495	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVCG412_12495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG412_12510	COG1733	regulation of RNA biosynthetic process
AVCG412_12525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVCG412_12530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVCG412_12535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG412_12540	COG1609	Transcriptional regulator
AVCG412_12545	COG1846	Transcriptional regulator
AVCG412_12555	COG0523	cobalamin synthesis protein
AVCG412_12570	COG3047	cAMP biosynthetic process
AVCG412_12595	COG0583	DNA-binding transcription factor activity
AVCG412_12625	COG0800	Aldolase
AVCG412_12630	COG2954	triphosphatase activity
AVCG412_12640	COG1309	transcriptional regulator
AVCG412_12650	COG1054	Belongs to the UPF0176 family
AVCG412_12655	COG2200	EAL domain
AVCG412_12655	COG2771	luxR family
AVCG412_12675	COG0673	inositol 2-dehydrogenase activity
AVCG412_12685	COG2115	Belongs to the xylose isomerase family
AVCG412_12690	COG1070	Carbohydrate kinase
AVCG412_12695	COG1609	Transcriptional regulator
AVCG412_12710	COG1309	transcriptional regulator
AVCG412_12715	COG1253	flavin adenine dinucleotide binding
AVCG412_12735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVCG412_12740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AVCG412_12790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVCG412_12810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVCG412_12815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVCG412_12820	COG3273	potassium ion transport
AVCG412_12820	COG0471	metal ion transport
AVCG412_12835	COG2274	protein secretion by the type I secretion system
AVCG412_12870	COG4172	Belongs to the ABC transporter superfamily
AVCG412_12875	COG1473	amidohydrolase
AVCG412_12890	COG0601	transmembrane transport
AVCG412_12895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_12900	COG0842	Transport permease protein
AVCG412_12905	COG1129	ABC transporter
AVCG412_12905	COG0842	Transport permease protein
AVCG412_12910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_12915	COG3191	aminopeptidase activity
AVCG412_12920	COG3454	Phosphonate metabolism
AVCG412_12935	COG0444	Belongs to the ABC transporter superfamily
AVCG412_12940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_12945	COG0601	transmembrane transport
AVCG412_12950	COG0747	negative chemotaxis
AVCG412_12960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG412_12965	COG1802	Transcriptional regulator
AVCG412_12970	COG1904	glucuronate isomerase
AVCG412_12975	COG1917	Cupin 2, conserved barrel domain protein
AVCG412_12985	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_12990	COG0246	Mannitol dehydrogenase
AVCG412_12995	COG1312	Catalyzes the dehydration of D-mannonate
AVCG412_13000	COG2721	sulfolactate sulfo-lyase activity
AVCG412_13015	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AVCG412_13030	COG4213	ABC transporter substrate-binding protein
AVCG412_13035	COG1129	ABC transporter
AVCG412_13040	COG4214	carbohydrate transport
AVCG412_13050	COG0129	dihydroxy-acid dehydratase activity
AVCG412_13065	COG3734	2-keto-3-deoxy-galactonokinase
AVCG412_13070	COG0800	Aldolase
AVCG412_13075	COG2832	Protein of unknown function (DUF454)
AVCG412_13080	COG0697	spore germination
AVCG412_13085	COG2186	Transcriptional regulator
AVCG412_13090	COG2807	transmembrane transport
AVCG412_13095	COG2373	Large extracellular alpha-helical protein
AVCG412_13100	COG4953	penicillin-binding protein 1C
AVCG412_13105	COG0840	transmembrane signaling receptor activity
AVCG412_13105	COG2972	Histidine kinase
AVCG412_13110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG412_13115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVCG412_13120	COG0438	transferase activity, transferring glycosyl groups
AVCG412_13130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_13135	COG0601	transmembrane transport
AVCG412_13140	COG0747	negative chemotaxis
AVCG412_13160	COG0438	transferase activity, transferring glycosyl groups
AVCG412_13190	COG0419	ATPase involved in DNA repair
AVCG412_13195	COG0840	transmembrane signaling receptor activity
AVCG412_13235	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVCG412_13245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_13250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG412_13260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVCG412_13275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG412_13285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVCG412_13315	COG0438	transferase activity, transferring glycosyl groups
AVCG412_13330	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AVCG412_13340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVCG412_13350	COG0789	Transcriptional regulator
AVCG412_13360	COG1793	dna ligase
AVCG412_13380	COG0783	Belongs to the Dps family
AVCG412_13390	COG0784	Response regulator, receiver
AVCG412_13430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG412_13445	COG0848	biopolymer transport protein
AVCG412_13455	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVCG412_13470	COG0010	Belongs to the arginase family
AVCG412_13490	COG1940	carbohydrate kinase activity
AVCG412_13510	COG1072	(Pantothenic acid kinase))
AVCG412_13515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_13520	COG0765	amino acid transport
AVCG412_13525	COG0765	amino acid transport
AVCG412_13530	COG4598	ABC transporter
AVCG412_13545	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_13550	COG1228	amidohydrolase
AVCG412_13555	COG2986	histidine ammonia-lyase
AVCG412_13565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AVCG412_13605	COG0583	DNA-binding transcription factor activity
AVCG412_13610	COG0346	lactoylglutathione lyase activity
AVCG412_13615	COG0400	carboxylic ester hydrolase activity
AVCG412_13635	COG3307	-O-antigen
AVCG412_13640	COG1596	polysaccharide export
AVCG412_13645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVCG412_13655	COG1215	transferase activity, transferring glycosyl groups
AVCG412_13660	COG2327	Polysaccharide pyruvyl transferase
AVCG412_13665	COG0463	Glycosyl transferase, family 2
AVCG412_13670	COG2244	polysaccharide biosynthetic process
AVCG412_13675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AVCG412_13680	COG2273	Hydrolase Family 16
AVCG412_13685	COG0438	transferase activity, transferring glycosyl groups
AVCG412_13690	COG1215	transferase activity, transferring glycosyl groups
AVCG412_13695	COG1215	transferase activity, transferring glycosyl groups
AVCG412_13700	COG1215	transferase activity, transferring glycosyl groups
AVCG412_13705	COG0489	protein tyrosine kinase activity
AVCG412_13705	COG3206	protein involved in exopolysaccharide biosynthesis
AVCG412_13710	COG0469	pyruvate kinase activity
AVCG412_13750	COG0542	response to heat
AVCG412_13760	COG2890	protein-(glutamine-N5) methyltransferase activity
AVCG412_13765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVCG412_13775	COG0527	aspartate kinase activity
AVCG412_13795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVCG412_13810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVCG412_13815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVCG412_13820	COG1040	competence protein
AVCG412_13825	COG2226	methyltransferase
AVCG412_13840	COG0494	nUDIX hydrolase
AVCG412_13850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AVCG412_13855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVCG412_13860	COG0653	protein targeting
AVCG412_13875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVCG412_13900	COG2963	transposase activity
AVCG412_13910	COG4372	Transposase
AVCG412_13955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVCG412_14065	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AVCG412_14070	COG1396	sequence-specific DNA binding
AVCG412_14085	COG2176	DNA-directed DNA polymerase activity
AVCG412_14090	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVCG412_14095	COG1061	Type III restriction enzyme res subunit
AVCG412_14105	COG1002	Type II restriction enzyme, methylase subunits
AVCG412_14140	COG5489	Protein of unknown function (DUF736)
AVCG412_14150	COG5489	Protein of unknown function (DUF736)
AVCG412_14155	COG4974	Belongs to the 'phage' integrase family
AVCG412_14160	COG0582	viral genome integration into host DNA
AVCG412_14165	COG4974	Belongs to the 'phage' integrase family
AVCG412_14170	COG5489	Protein of unknown function (DUF736)
AVCG412_14175	COG5489	Protein of unknown function (DUF736)
AVCG412_14245	COG0741	lytic transglycosylase activity
AVCG412_14270	COG4962	Type ii secretion system protein e
AVCG412_14285	COG3451	type IV secretory pathway VirB4
AVCG412_14300	COG3846	protein secretion by the type IV secretion system
AVCG412_14315	COG2948	multi-organism process
AVCG412_14330	COG0165	Argininosuccinate lyase
AVCG412_14340	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_14345	COG3842	ATPase activity
AVCG412_14370	COG0583	DNA-binding transcription factor activity
AVCG412_14380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVCG412_14390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_14400	COG0483	inositol monophosphate 1-phosphatase activity
AVCG412_14410	COG3842	ATPase activity
AVCG412_14420	COG1175	transmembrane transport
AVCG412_14430	COG1846	Transcriptional regulator
AVCG412_14430	COG1940	carbohydrate kinase activity
AVCG412_14435	COG3842	ATPase activity
AVCG412_14450	COG1175	transmembrane transport
AVCG412_14455	COG0395	ABC-type sugar transport system, permease component
AVCG412_14460	COG0584	glycerophosphoryl diester phosphodiesterase
AVCG412_14465	COG0483	inositol monophosphate 1-phosphatase activity
AVCG412_14510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVCG412_14520	COG0300	oxidoreductase activity
AVCG412_14535	COG2086	electron transfer activity
AVCG412_14545	COG2972	Histidine kinase
AVCG412_14545	COG0840	transmembrane signaling receptor activity
AVCG412_14550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVCG412_14555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVCG412_14560	COG0165	Argininosuccinate lyase
AVCG412_14570	COG0019	diaminopimelate decarboxylase activity
AVCG412_14585	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVCG412_14600	COG2884	Cell division ATP-binding protein ftsE
AVCG412_14620	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AVCG412_14630	COG0287	Prephenate dehydrogenase
AVCG412_14635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVCG412_14640	COG2226	methyltransferase
AVCG412_14645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG412_14670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVCG412_14675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AVCG412_14705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVCG412_14710	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVCG412_14720	COG4974	Belongs to the 'phage' integrase family
AVCG412_14725	COG0825	malonyl-CoA metabolic process
AVCG412_14730	COG3034	peptidoglycan biosynthetic process
AVCG412_14740	COG0523	cobalamin synthesis protein
AVCG412_14745	COG1686	Belongs to the peptidase S11 family
AVCG412_14750	COG1473	amidohydrolase
AVCG412_14760	COG0628	permease
AVCG412_14770	COG2771	luxR family
AVCG412_14775	COG1766	The M ring may be actively involved in energy transduction
AVCG412_14785	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVCG412_14790	COG0745	RESPONSE REGULATOR receiver
AVCG412_14795	COG2201	protein-glutamate methylesterase activity
AVCG412_14800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG412_14805	COG0835	chemotaxis
AVCG412_14810	COG0643	Histidine kinase
AVCG412_14810	COG2198	Histidine kinase
AVCG412_14815	COG0745	RESPONSE REGULATOR receiver
AVCG412_14825	COG0840	transmembrane signaling receptor activity
AVCG412_14830	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVCG412_14840	COG0156	8-amino-7-oxononanoate synthase activity
AVCG412_14850	COG0729	surface antigen
AVCG412_14865	COG0835	chemotaxis
AVCG412_14870	COG2223	nitrite transmembrane transporter activity
AVCG412_14880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AVCG412_14885	COG3383	formate dehydrogenase (NAD+) activity
AVCG412_14905	COG0640	Transcriptional regulator
AVCG412_14910	COG0039	L-malate dehydrogenase activity
AVCG412_14915	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVCG412_14920	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVCG412_14925	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVCG412_14930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVCG412_14935	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVCG412_14950	COG2972	Histidine kinase
AVCG412_14950	COG0840	transmembrane signaling receptor activity
AVCG412_14960	COG4974	Belongs to the 'phage' integrase family
AVCG412_14975	COG1280	lysine exporter protein (LysE YggA)
AVCG412_14985	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVCG412_14995	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AVCG412_15005	COG0045	succinate-CoA ligase (ADP-forming) activity
AVCG412_15010	COG0039	L-malate dehydrogenase activity
AVCG412_15015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVCG412_15065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVCG412_15070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVCG412_15075	COG0181	hydroxymethylbilane synthase activity
AVCG412_15115	COG1872	DUF167
AVCG412_15120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVCG412_15130	COG1217	gtp-binding protein TYPA
AVCG412_15140	COG0339	signal peptide processing
AVCG412_15150	COG0137	argininosuccinate synthase activity
AVCG412_15165	COG1280	lysine exporter protein (LysE YggA)
AVCG412_15175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVCG412_15190	COG2154	pterin-4-alpha-carbinolamine dehydratase
AVCG412_15195	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AVCG412_15205	COG1136	(ABC) transporter
AVCG412_15210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVCG412_15215	COG0670	Belongs to the BI1 family
AVCG412_15235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVCG412_15240	COG4133	protoheme IX ABC transporter activity
AVCG412_15245	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVCG412_15250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVCG412_15270	COG2917	probably involved in intracellular septation
AVCG412_15275	COG0552	protein localization to endoplasmic reticulum
AVCG412_15280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVCG412_15285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVCG412_15300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVCG412_15305	COG1605	Chorismate mutase
AVCG412_15305	COG0287	Prephenate dehydrogenase
AVCG412_15310	COG0228	four-way junction DNA binding
AVCG412_15315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVCG412_15320	COG0336	Belongs to the RNA methyltransferase TrmD family
AVCG412_15330	COG0335	large ribosomal subunit rRNA binding
AVCG412_15345	COG2372	response to copper ion
AVCG412_15350	COG1276	copper resistance
AVCG412_15355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_15360	COG0765	amino acid transport
AVCG412_15375	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVCG412_15390	COG0745	RESPONSE REGULATOR receiver
AVCG412_15405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVCG412_15410	COG1674	ftsk spoiiie
AVCG412_15415	COG0004	ammonium transporteR
AVCG412_15420	COG0347	Belongs to the P(II) protein family
AVCG412_15425	COG1946	Acyl-CoA thioesterase
AVCG412_15430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG412_15435	COG2835	tetraacyldisaccharide 4'-kinase activity
AVCG412_15440	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVCG412_15445	COG3118	belongs to the thioredoxin family
AVCG412_15465	COG2017	converts alpha-aldose to the beta-anomer
AVCG412_15480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AVCG412_15500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVCG412_15510	COG0488	(ABC) transporter
AVCG412_15540	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AVCG412_15570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVCG412_15575	COG0799	negative regulation of ribosome biogenesis
AVCG412_15580	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVCG412_15585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVCG412_15590	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVCG412_15595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVCG412_15615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVCG412_15620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVCG412_15640	COG0138	bifunctional purine biosynthesis protein purh
AVCG412_15650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVCG412_15650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVCG412_15655	COG0501	Belongs to the peptidase M48B family
AVCG412_15675	COG0793	Belongs to the peptidase S41A family
AVCG412_15685	COG0494	nUDIX hydrolase
AVCG412_15715	COG2201	protein-glutamate methylesterase activity
AVCG412_15720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG412_15725	COG0835	chemotaxis
AVCG412_15730	COG0840	transmembrane signaling receptor activity
AVCG412_15735	COG0840	transmembrane signaling receptor activity
AVCG412_15735	COG3290	protein histidine kinase activity
AVCG412_15740	COG0840	transmembrane signaling receptor activity
AVCG412_15745	COG0835	chemotaxis
AVCG412_15750	COG0643	Histidine kinase
AVCG412_15750	COG2198	Histidine kinase
AVCG412_15755	COG0745	RESPONSE REGULATOR receiver
AVCG412_15780	COG1522	sequence-specific DNA binding
AVCG412_15795	COG4221	oxidoreductase activity
AVCG412_15800	COG0156	8-amino-7-oxononanoate synthase activity
AVCG412_15810	COG0738	Major facilitator superfamily
AVCG412_15815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AVCG412_15820	COG2885	chlorophyll binding
AVCG412_15830	COG0142	geranyltranstransferase activity
AVCG412_15835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVCG412_15845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVCG412_15850	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AVCG412_15885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVCG412_15915	COG0066	3-isopropylmalate dehydratase activity
AVCG412_15920	COG0473	3-isopropylmalate dehydrogenase activity
AVCG412_15925	COG0671	phosphoesterase, PA-phosphatase related
AVCG412_15940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVCG412_15950	COG2010	Cytochrome c
AVCG412_15955	COG0288	reversible hydration of carbon dioxide
AVCG412_15960	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AVCG412_15965	COG2902	Dehydrogenase
AVCG412_15975	COG3459	Glycosyltransferase 36 associated
AVCG412_15980	COG1473	amidohydrolase
AVCG412_15995	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AVCG412_16005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVCG412_16015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVCG412_16020	COG0495	leucyl-tRNA aminoacylation
AVCG412_16045	COG0357	Ribosomal RNA small subunit methyltransferase G
AVCG412_16050	COG0445	tRNA wobble uridine modification
AVCG412_16055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVCG412_16060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVCG412_16065	COG1981	membrane
AVCG412_16070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVCG412_16075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVCG412_16080	COG0424	maF-like protein
AVCG412_16085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVCG412_16090	COG0237	dephospho-CoA kinase activity
AVCG412_16100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVCG412_16115	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AVCG412_16155	COG0135	phosphoribosylanthranilate isomerase activity
AVCG412_16160	COG0133	tryptophan synthase activity
AVCG412_16165	COG0159	tryptophan synthase activity
AVCG412_16170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVCG412_16175	COG0285	dihydrofolate synthase activity
AVCG412_16200	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVCG412_16205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVCG412_16210	COG0131	Imidazoleglycerol-phosphate dehydratase
AVCG412_16215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVCG412_16220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVCG412_16225	COG0107	imidazoleglycerol-phosphate synthase activity
AVCG412_16230	COG0140	phosphoribosyl-ATP diphosphatase activity
AVCG412_16235	COG1072	(Pantothenic acid kinase))
AVCG412_16250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AVCG412_16255	COG0745	RESPONSE REGULATOR receiver
AVCG412_16260	COG0642	Histidine kinase
AVCG412_16270	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVCG412_16270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVCG412_16275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVCG412_16280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVCG412_16285	COG2205	protein histidine kinase activity
AVCG412_16290	COG3178	'Phosphotransferase
AVCG412_16295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVCG412_16310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVCG412_16325	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AVCG412_16335	COG1643	Atp-dependent helicase
AVCG412_16340	COG2423	ornithine cyclodeaminase activity
AVCG412_16380	COG2814	Major facilitator Superfamily
AVCG412_16385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG412_16390	COG1609	Transcriptional regulator
AVCG412_16400	COG0673	inositol 2-dehydrogenase activity
AVCG412_16410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG412_16415	COG3962	Belongs to the TPP enzyme family
AVCG412_16430	COG3718	enzyme involved in inositol metabolism
AVCG412_16455	COG4221	oxidoreductase activity
AVCG412_16460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG412_16475	COG1595	DNA-templated transcription, initiation
AVCG412_16480	COG3806	Anti-sigma factor
AVCG412_16500	COG3842	ATPase activity
AVCG412_16505	COG3842	ATPase activity
AVCG412_16515	COG0395	ABC-type sugar transport system, permease component
AVCG412_16530	COG3474	cytochrome
AVCG412_16535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVCG412_16540	COG0077	Prephenate dehydratase
AVCG412_16540	COG1605	Chorismate mutase
AVCG412_16550	COG2816	NAD+ diphosphatase activity
AVCG412_16565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVCG412_16570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVCG412_16580	COG3422	double-strand break repair
AVCG412_16595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVCG412_16600	COG0481	GTPase activity
AVCG412_16615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVCG412_16620	COG1607	acyl-coa hydrolase
AVCG412_16645	COG1393	Belongs to the ArsC family
AVCG412_16650	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVCG412_16655	COG2309	aminopeptidase activity
AVCG412_16670	COG1278	Cold shock
AVCG412_16675	COG1570	exodeoxyribonuclease VII activity
AVCG412_16720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AVCG412_16725	COG4644	lycopene metabolic process
AVCG412_16775	COG0625	glutathione transferase activity
AVCG412_16785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG412_16795	COG4689	acetoacetate decarboxylase
AVCG412_16805	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_16820	COG0840	transmembrane signaling receptor activity
AVCG412_16835	COG4584	PFAM Integrase catalytic
AVCG412_16845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AVCG412_16855	COG1280	lysine exporter protein (LysE YggA)
AVCG412_16880	COG4191	Histidine kinase
AVCG412_16880	COG0784	Response regulator, receiver
AVCG412_16940	COG3300	MHYT domain
AVCG412_16940	COG5001	Diguanylate cyclase
AVCG412_16965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG412_16975	COG3920	Histidine kinase
AVCG412_16980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG412_16990	COG0698	ribose 5-phosphate isomerase
AVCG412_17000	COG0765	amino acid transport
AVCG412_17005	COG0765	amino acid transport
AVCG412_17045	COG1396	sequence-specific DNA binding
AVCG412_17050	COG3706	GGDEF domain
AVCG412_17050	COG4251	negative regulation of phosphorylation
AVCG412_17050	COG5001	Diguanylate cyclase
AVCG412_17050	COG2203	Gaf domain
AVCG412_17070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AVCG412_17075	COG4644	lycopene metabolic process
AVCG412_17090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVCG412_17095	COG2951	lytic endotransglycosylase activity
AVCG412_17125	COG2814	Major facilitator Superfamily
AVCG412_17130	COG0779	Required for maturation of 30S ribosomal subunits
AVCG412_17135	COG0195	Participates in both transcription termination and antitermination
AVCG412_17135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVCG412_17145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVCG412_17150	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVCG412_17155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVCG412_17160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVCG412_17165	COG1185	polyribonucleotide nucleotidyltransferase activity
AVCG412_17170	COG2813	Specifically methylates the guanine in position
AVCG412_17175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVCG412_17185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVCG412_17195	COG2860	membrane
AVCG412_17205	COG0477	Major facilitator Superfamily
AVCG412_17230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVCG412_17235	COG0539	negative regulation of cytoplasmic translation
AVCG412_17260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVCG412_17275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVCG412_17280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVCG412_17285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVCG412_17295	COG0072	phenylalanine-tRNA ligase activity
AVCG412_17295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVCG412_17340	COG4964	Belongs to the GSP D family
AVCG412_17375	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVCG412_17380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVCG412_17385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVCG412_17395	COG0588	phosphoglycerate mutase activity
AVCG412_17400	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVCG412_17405	COG1132	(ABC) transporter
AVCG412_17410	COG0837	glucose binding
AVCG412_17415	COG1803	Methylglyoxal synthase
AVCG412_17420	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AVCG412_17425	COG4166	transmembrane transport
AVCG412_17430	COG4174	ABC transporter (Permease)
AVCG412_17435	COG4239	(ABC) transporter, permease
AVCG412_17440	COG4172	Belongs to the ABC transporter superfamily
AVCG412_17445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVCG412_17455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVCG412_17465	COG0604	alcohol dehydrogenase
AVCG412_17485	COG1802	Transcriptional regulator
AVCG412_17485	COG4626	Terminase
AVCG412_17560	COG1744	ABC transporter substrate-binding protein PnrA-like
AVCG412_17565	COG3845	ABC transporter
AVCG412_17570	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG412_17575	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG412_17590	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AVCG412_17595	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AVCG412_17600	COG2188	Transcriptional regulator
AVCG412_17605	COG3624	Phosphonate C-P lyase system protein PhnG
AVCG412_17610	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AVCG412_17615	COG3626	phosphonate metabolism
AVCG412_17620	COG3627	carbon phosphorus lyase activity
AVCG412_17625	COG4107	phosphonate C-P lyase system protein PhnK
AVCG412_17630	COG4778	phosphonate C-P lyase system protein PhnL
AVCG412_17640	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVCG412_17645	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AVCG412_17655	COG3639	organic phosphonate transmembrane transporter activity
AVCG412_17660	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVCG412_17665	COG3454	Phosphonate metabolism
AVCG412_17670	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVCG412_17685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVCG412_17690	COG2353	YceI-like domain
AVCG412_17695	COG2353	YceI-like domain
AVCG412_17705	COG0791	NLP P60 protein
AVCG412_17710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVCG412_17710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVCG412_17720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG412_17725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVCG412_17740	COG0443	Heat shock 70 kDa protein
AVCG412_17750	COG0484	heat shock protein binding
AVCG412_17755	COG2900	Belongs to the SlyX family
AVCG412_17760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVCG412_17775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG412_17785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG412_17790	COG5001	Diguanylate cyclase
AVCG412_17795	COG3002	Belongs to the UPF0753 family
AVCG412_17800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVCG412_17825	COG0519	Catalyzes the synthesis of GMP from XMP
AVCG412_17825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVCG412_17840	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AVCG412_17865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVCG412_17865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVCG412_17870	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVCG412_17880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVCG412_17890	COG1968	undecaprenyl-diphosphatase activity
AVCG412_17910	COG0284	orotidine-5'-phosphate decarboxylase activity
AVCG412_17920	COG3963	phosphatidate phosphatase activity
AVCG412_17930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVCG412_17935	COG0792	nuclease activity
AVCG412_17940	COG1653	transport
AVCG412_17945	COG1175	transmembrane transport
AVCG412_17950	COG0395	ABC-type sugar transport system, permease component
AVCG412_17955	COG3842	ATPase activity
AVCG412_17965	COG0189	ligase activity
AVCG412_17970	COG0606	chelatase, subunit chli
AVCG412_17985	COG1280	lysine exporter protein (LysE YggA)
AVCG412_17995	COG0756	dUTP diphosphatase activity
AVCG412_18000	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AVCG412_18005	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AVCG412_18010	COG1877	trehalose-phosphatase activity
AVCG412_18030	COG1741	Belongs to the pirin family
AVCG412_18040	COG0583	DNA-binding transcription factor activity
AVCG412_18055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVCG412_18060	COG3920	Histidine kinase
AVCG412_18065	COG0784	Response regulator, receiver
AVCG412_18070	COG2205	protein histidine kinase activity
AVCG412_18070	COG2198	Histidine kinase
AVCG412_18070	COG0784	Response regulator, receiver
AVCG412_18070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_18075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVCG412_18080	COG2226	methyltransferase
AVCG412_18085	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVCG412_18090	COG0268	Binds directly to 16S ribosomal RNA
AVCG412_18100	COG1192	Involved in chromosome partitioning
AVCG412_18105	COG1475	DNA binding
AVCG412_18110	COG1414	Transcriptional regulator
AVCG412_18115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVCG412_18120	COG0392	lysyltransferase activity
AVCG412_18135	COG3257	ureidoglycine aminohydrolase activity
AVCG412_18150	COG1522	sequence-specific DNA binding
AVCG412_18175	COG2040	homocysteine
AVCG412_18180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG412_18190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVCG412_18195	COG1473	amidohydrolase
AVCG412_18205	COG0297	glycogen (starch) synthase activity
AVCG412_18230	COG1063	alcohol dehydrogenase
AVCG412_18235	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG412_18240	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_18245	COG3265	gluconokinase activity
AVCG412_18250	COG2084	Dehydrogenase
AVCG412_18260	COG1609	Transcriptional regulator
AVCG412_18275	COG1129	ABC transporter
AVCG412_18290	COG1879	ABC-type sugar transport system periplasmic component
AVCG412_18295	COG1129	ABC transporter
AVCG412_18300	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_18305	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_18310	COG2186	Transcriptional regulator
AVCG412_18315	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_18320	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_18330	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG412_18340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG412_18345	COG1116	anion transmembrane transporter activity
AVCG412_18365	COG0778	Nitroreductase
AVCG412_18375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG412_18380	COG0659	secondary active sulfate transmembrane transporter activity
AVCG412_18385	COG0589	response to stress
AVCG412_18440	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVCG412_18455	COG1802	Transcriptional regulator
AVCG412_18465	COG2723	6-phospho-beta-galactosidase activity
AVCG412_18470	COG0601	transmembrane transport
AVCG412_18480	COG3964	amidohydrolase
AVCG412_18495	COG1921	L-seryl-tRNASec selenium transferase activity
AVCG412_18500	COG2203	Gaf domain
AVCG412_18500	COG3706	GGDEF domain
AVCG412_18500	COG4251	negative regulation of phosphorylation
AVCG412_18500	COG5001	Diguanylate cyclase
AVCG412_18520	COG2080	2 iron, 2 sulfur cluster binding
AVCG412_18525	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVCG412_18530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG412_18555	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_18560	COG0656	L-ascorbic acid biosynthetic process
AVCG412_18565	COG0583	DNA-binding transcription factor activity
AVCG412_18570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVCG412_18575	COG1486	melibiose metabolic process
AVCG412_18580	COG4172	Belongs to the ABC transporter superfamily
AVCG412_18585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_18590	COG0601	transmembrane transport
AVCG412_18595	COG0747	negative chemotaxis
AVCG412_18600	COG1486	melibiose metabolic process
AVCG412_18605	COG2207	Transcriptional regulator
AVCG412_18605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVCG412_18635	COG1063	alcohol dehydrogenase
AVCG412_18640	COG4948	Mandelate Racemase Muconate Lactonizing
AVCG412_18660	COG4214	carbohydrate transport
AVCG412_18665	COG1129	ABC transporter
AVCG412_18680	COG1175	transmembrane transport
AVCG412_18685	COG0395	ABC-type sugar transport system, permease component
AVCG412_18705	COG1609	Transcriptional regulator
AVCG412_18710	COG2972	Histidine kinase
AVCG412_18710	COG0840	transmembrane signaling receptor activity
AVCG412_18735	COG0667	Aldo Keto reductase
AVCG412_18750	COG1129	ABC transporter
AVCG412_18760	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_18775	COG0765	amino acid transport
AVCG412_18780	COG1126	abc transporter atp-binding protein
AVCG412_18785	COG2079	MmgE PrpD family protein
AVCG412_18790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_18810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_18835	COG2197	response regulator
AVCG412_18845	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AVCG412_18870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG412_18890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG412_18900	COG1960	acyl-CoA dehydrogenase activity
AVCG412_18910	COG1309	transcriptional regulator
AVCG412_18940	COG2207	Transcriptional regulator
AVCG412_18950	COG0235	Class ii aldolase
AVCG412_18970	COG0300	oxidoreductase activity
AVCG412_18995	COG1595	DNA-templated transcription, initiation
AVCG412_19005	COG2824	Alkylphosphonate utilization operon protein PhnA
AVCG412_19030	COG0395	ABC-type sugar transport system, permease component
AVCG412_19035	COG3842	ATPase activity
AVCG412_19040	COG0584	glycerophosphoryl diester phosphodiesterase
AVCG412_19085	COG1414	Transcriptional regulator
AVCG412_19125	COG2814	Major facilitator Superfamily
AVCG412_19130	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_19150	COG3485	protocatechuate 3,4-dioxygenase
AVCG412_19170	COG3335	DDE superfamily endonuclease
AVCG412_19185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_19200	COG4957	zinc ion binding
AVCG412_19235	COG1320	monovalent cation:proton antiporter activity
AVCG412_19240	COG2212	antiporter activity
AVCG412_19245	COG1863	multisubunit Na H antiporter MnhE subunit
AVCG412_19250	COG0651	ATP synthesis coupled electron transport
AVCG412_19255	COG1006	Multisubunit Na H antiporter MnhC subunit
AVCG412_19260	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVCG412_19260	COG2111	Na H antiporter
AVCG412_19280	COG3845	ABC transporter
AVCG412_19285	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVCG412_19290	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG412_19295	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_19300	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_19315	COG2072	flavoprotein involved in K transport
AVCG412_19320	COG1177	transmembrane transport
AVCG412_19325	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_19330	COG3842	ATPase activity
AVCG412_19335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AVCG412_19340	COG0583	DNA-binding transcription factor activity
AVCG412_19365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_19370	COG4172	Belongs to the ABC transporter superfamily
AVCG412_19375	COG4608	Belongs to the ABC transporter superfamily
AVCG412_19400	COG0601	transmembrane transport
AVCG412_19405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_19425	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_19430	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_19435	COG1846	Transcriptional regulator
AVCG412_19465	COG0625	glutathione transferase activity
AVCG412_19485	COG2133	pyrroloquinoline quinone binding
AVCG412_19495	COG0438	transferase activity, transferring glycosyl groups
AVCG412_19510	COG0753	catalase activity
AVCG412_19515	COG0306	phosphate transporter
AVCG412_19530	COG3684	Belongs to the aldolase LacD family
AVCG412_19535	COG2390	Transcriptional regulator
AVCG412_19555	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_19560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG412_19565	COG0626	cystathionine gamma-synthase activity
AVCG412_19570	COG1725	Transcriptional regulator
AVCG412_19575	COG0747	negative chemotaxis
AVCG412_19580	COG0601	transmembrane transport
AVCG412_19585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_19590	COG0444	Belongs to the ABC transporter superfamily
AVCG412_19595	COG4608	Belongs to the ABC transporter superfamily
AVCG412_19610	COG0747	negative chemotaxis
AVCG412_19620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_19625	COG0405	Gamma-glutamyltransferase
AVCG412_19635	COG0754	glutathionylspermidine amidase activity
AVCG412_19645	COG3766	membrane
AVCG412_19655	COG3789	protein conserved in bacteria
AVCG412_19670	COG0318	PFAM AMP-dependent synthetase and ligase
AVCG412_19680	COG1802	Transcriptional regulator
AVCG412_19690	COG0601	transmembrane transport
AVCG412_19695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_19720	COG0747	negative chemotaxis
AVCG412_19730	COG2205	protein histidine kinase activity
AVCG412_19735	COG2197	response regulator
AVCG412_19740	COG4585	Histidine kinase
AVCG412_19755	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVCG412_19760	COG4208	sulfate ABC transporter
AVCG412_19765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVCG412_19770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AVCG412_19775	COG1609	Transcriptional regulator
AVCG412_19780	COG0673	inositol 2-dehydrogenase activity
AVCG412_19790	COG1653	transport
AVCG412_19795	COG1175	transmembrane transport
AVCG412_19800	COG0395	ABC-type sugar transport system, permease component
AVCG412_19805	COG3842	ATPase activity
AVCG412_19815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVCG412_19830	COG0583	DNA-binding transcription factor activity
AVCG412_19835	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_19840	COG3250	beta-galactosidase activity
AVCG412_19850	COG1940	carbohydrate kinase activity
AVCG412_19855	COG2116	formate transmembrane transporter activity
AVCG412_19860	COG0402	S-adenosylhomocysteine deaminase activity
AVCG412_19870	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG412_19875	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVCG412_19880	COG3845	ABC transporter
AVCG412_19905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVCG412_19910	COG0583	DNA-binding transcription factor activity
AVCG412_19925	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AVCG412_19940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG412_19945	COG2080	2 iron, 2 sulfur cluster binding
AVCG412_19950	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_19965	COG2186	Transcriptional regulator
AVCG412_19970	COG1304	FMN binding
AVCG412_19980	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVCG412_20025	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVCG412_20030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVCG412_20035	COG1126	abc transporter atp-binding protein
AVCG412_20040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_20045	COG0765	amino acid transport
AVCG412_20050	COG0765	amino acid transport
AVCG412_20060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVCG412_20070	COG1764	response to oxidative stress
AVCG412_20085	COG1116	anion transmembrane transporter activity
AVCG412_20090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG412_20095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG412_20100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG412_20105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_20110	COG1959	2 iron, 2 sulfur cluster binding
AVCG412_20135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_20170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG412_20190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG412_20200	COG1116	anion transmembrane transporter activity
AVCG412_20210	COG4191	Histidine kinase
AVCG412_20215	COG4566	intracellular signal transduction
AVCG412_20225	COG3842	ATPase activity
AVCG412_20230	COG0395	ABC-type sugar transport system, permease component
AVCG412_20235	COG1175	transmembrane transport
AVCG412_20270	COG1940	carbohydrate kinase activity
AVCG412_20275	COG0747	negative chemotaxis
AVCG412_20280	COG0601	transmembrane transport
AVCG412_20285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_20295	COG4608	Belongs to the ABC transporter superfamily
AVCG412_20300	COG0745	RESPONSE REGULATOR receiver
AVCG412_20315	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVCG412_20325	COG2076	Multidrug Resistance protein
AVCG412_20345	COG2076	Multidrug Resistance protein
AVCG412_20365	COG1215	transferase activity, transferring glycosyl groups
AVCG412_20380	COG3920	Histidine kinase
AVCG412_20380	COG2202	Pas domain
AVCG412_20390	COG0784	Response regulator, receiver
AVCG412_20400	COG1162	GTPase activity
AVCG412_20405	COG0784	Response regulator, receiver
AVCG412_20405	COG4191	Histidine kinase
AVCG412_20410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG412_20425	COG1126	abc transporter atp-binding protein
AVCG412_20430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG412_20435	COG1609	Transcriptional regulator
AVCG412_20440	COG0840	transmembrane signaling receptor activity
AVCG412_20440	COG2972	Histidine kinase
AVCG412_20445	COG0835	chemotaxis
AVCG412_20450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG412_20455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG412_20470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG412_20480	COG0789	Transcriptional regulator
AVCG412_20490	COG0366	Alpha amylase catalytic
AVCG412_20495	COG0366	Alpha amylase catalytic
AVCG412_20500	COG1640	4-alpha-glucanotransferase
AVCG412_20505	COG1278	Cold shock
AVCG412_20510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVCG412_20520	COG0673	inositol 2-dehydrogenase activity
AVCG412_20530	COG1802	Transcriptional regulator
AVCG412_20535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG412_20545	COG0673	inositol 2-dehydrogenase activity
AVCG412_20555	COG1175	transmembrane transport
AVCG412_20560	COG0395	ABC-type sugar transport system, permease component
AVCG412_20570	COG0673	inositol 2-dehydrogenase activity
AVCG412_20580	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AVCG412_20590	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_20595	COG3920	Histidine kinase
AVCG412_20595	COG2202	Pas domain
AVCG412_20600	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AVCG412_20605	COG3920	Histidine kinase
AVCG412_20620	COG3685	Protein conserved in bacteria
AVCG412_20650	COG5001	Diguanylate cyclase
AVCG412_20670	COG1132	(ABC) transporter
AVCG412_20675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVCG412_20675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG412_20690	COG3842	ATPase activity
AVCG412_20695	COG3833	ABC-type maltose transport systems, permease component
AVCG412_20740	COG0604	alcohol dehydrogenase
AVCG412_20740	COG3321	synthase
AVCG412_20760	COG1960	acyl-CoA dehydrogenase activity
AVCG412_20770	COG4608	Belongs to the ABC transporter superfamily
AVCG412_20785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_20790	COG0747	negative chemotaxis
AVCG412_20810	COG0583	DNA-binding transcription factor activity
AVCG412_20815	COG0747	negative chemotaxis
AVCG412_20820	COG0601	transmembrane transport
AVCG412_20825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_20840	COG0154	amidase activity
AVCG412_20855	COG1335	isochorismatase
AVCG412_20860	COG3845	ABC transporter
AVCG412_20875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVCG412_20880	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG412_20900	COG4172	Belongs to the ABC transporter superfamily
AVCG412_20905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_20910	COG0601	transmembrane transport
AVCG412_20940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_20950	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_20960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG412_20965	COG1309	transcriptional regulator
AVCG412_20980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVCG412_20995	COG4770	biotin carboxylase activity
AVCG412_21010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AVCG412_21010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AVCG412_21040	COG0765	amino acid transport
AVCG412_21045	COG0765	amino acid transport
AVCG412_21055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG412_21070	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_21075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG412_21075	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AVCG412_21080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG412_21090	COG4172	Belongs to the ABC transporter superfamily
AVCG412_21100	COG0601	transmembrane transport
AVCG412_21105	COG0747	negative chemotaxis
AVCG412_21110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG412_21115	COG2186	Transcriptional regulator
AVCG412_21140	COG1175	transmembrane transport
AVCG412_21145	COG0395	ABC-type sugar transport system, permease component
AVCG412_21155	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVCG412_21165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_21170	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_21175	COG2084	Dehydrogenase
AVCG412_21185	COG3386	PFAM SMP-30 Gluconolaconase
AVCG412_21195	COG2771	luxR family
AVCG412_21205	COG0626	cystathionine gamma-synthase activity
AVCG412_21220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG412_21255	COG1175	transmembrane transport
AVCG412_21260	COG0395	ABC-type sugar transport system, permease component
AVCG412_21285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG412_21285	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVCG412_21290	COG4311	Sarcosine oxidase, delta subunit
AVCG412_21295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_21300	COG4977	sequence-specific DNA binding
AVCG412_21310	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVCG412_21315	COG2218	PFAM glutamate synthase alpha subunit domain protein
AVCG412_21320	COG0069	glutamate synthase activity
AVCG412_21335	COG1304	FMN binding
AVCG412_21350	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVCG412_21360	COG3842	ATPase activity
AVCG412_21365	COG1175	transmembrane transport
AVCG412_21370	COG0395	ABC-type sugar transport system, permease component
AVCG412_21390	COG0412	Dienelactone hydrolase
AVCG412_21400	COG0583	DNA-binding transcription factor activity
AVCG412_21410	COG0583	DNA-binding transcription factor activity
AVCG412_21435	COG0306	phosphate transporter
AVCG412_21450	COG0277	FAD linked oxidase domain protein
AVCG412_21455	COG0277	FAD linked oxidase domain protein
AVCG412_21465	COG0247	lactate metabolic process
AVCG412_21475	COG0625	glutathione transferase activity
AVCG412_21485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVCG412_21490	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AVCG412_21505	COG2852	Protein conserved in bacteria
AVCG412_21510	COG0124	histidyl-tRNA synthetase
AVCG412_21540	COG2818	Glycosylase
AVCG412_21545	COG1388	LysM domain
AVCG412_21545	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG412_21550	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG412_21565	COG0459	protein refolding
AVCG412_21570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVCG412_21575	COG2059	Chromate
AVCG412_21585	COG0196	riboflavin kinase activity
AVCG412_21600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AVCG412_21615	COG2130	NADP-dependent
AVCG412_21620	COG2137	regulation of response to DNA damage stimulus
AVCG412_21630	COG2909	trisaccharide binding
AVCG412_21645	COG3842	ATPase activity
AVCG412_21655	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_21660	COG1177	transmembrane transport
AVCG412_21665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVCG412_21670	COG0019	diaminopimelate decarboxylase activity
AVCG412_21680	COG4770	biotin carboxylase activity
AVCG412_21685	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG412_21690	COG4336	lyase activity
AVCG412_21695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG412_21700	COG1914	H( )-stimulated, divalent metal cation uptake system
AVCG412_21705	COG1802	Transcriptional regulator
AVCG412_21710	COG1522	sequence-specific DNA binding
AVCG412_21715	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AVCG412_21740	COG0583	DNA-binding transcription factor activity
AVCG412_21745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG412_21750	COG0511	ligase activity, forming carbon-carbon bonds
AVCG412_21755	COG0439	Biotin carboxylase
AVCG412_21765	COG1984	allophanate hydrolase subunit 2
AVCG412_21775	COG3842	ATPase activity
AVCG412_21780	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_21790	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_21795	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_21805	COG3842	ATPase activity
AVCG412_21810	COG0726	polysaccharide deacetylase
AVCG412_21820	COG0523	cobalamin synthesis protein
AVCG412_21835	COG1522	sequence-specific DNA binding
AVCG412_21840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_21845	COG0659	secondary active sulfate transmembrane transporter activity
AVCG412_21855	COG0243	molybdopterin cofactor binding
AVCG412_21865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVCG412_21870	COG1116	anion transmembrane transporter activity
AVCG412_21875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG412_21880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG412_21885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG412_21890	COG3707	response regulator
AVCG412_21910	COG0583	DNA-binding transcription factor activity
AVCG412_21915	COG1960	acyl-CoA dehydrogenase activity
AVCG412_21920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVCG412_21950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AVCG412_21965	COG2022	thiamine diphosphate biosynthetic process
AVCG412_22005	COG4372	Transposase
AVCG412_22015	COG2963	transposase activity
AVCG412_22050	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVCG412_22190	COG0640	Transcriptional regulator
AVCG412_22200	COG0798	PFAM Bile acid sodium symporter
AVCG412_22210	COG0431	NADPH-dependent FMN reductase
AVCG412_22220	COG0745	RESPONSE REGULATOR receiver
AVCG412_22225	COG2205	protein histidine kinase activity
AVCG412_22230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AVCG412_22240	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AVCG412_22265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG412_22270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVCG412_22275	COG1522	sequence-specific DNA binding
AVCG412_22290	COG2267	carboxylic ester hydrolase activity
AVCG412_22300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_22305	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_22320	COG1177	transmembrane transport
AVCG412_22325	COG3842	ATPase activity
AVCG412_22330	COG1012	belongs to the aldehyde dehydrogenase family
AVCG412_22340	COG4154	Belongs to the RbsD FucU family
AVCG412_22350	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_22360	COG1129	ABC transporter
AVCG412_22380	COG2721	sulfolactate sulfo-lyase activity
AVCG412_22390	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_22405	COG0745	RESPONSE REGULATOR receiver
AVCG412_22440	COG0183	Belongs to the thiolase family
AVCG412_22445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVCG412_22455	COG1414	Transcriptional regulator
AVCG412_22470	COG0583	DNA-binding transcription factor activity
AVCG412_22480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVCG412_22485	COG3485	protocatechuate 3,4-dioxygenase
AVCG412_22490	COG3485	protocatechuate 3,4-dioxygenase
AVCG412_22495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVCG412_22500	COG0604	alcohol dehydrogenase
AVCG412_22510	COG3842	ATPase activity
AVCG412_22525	COG0668	transmembrane transport
AVCG412_22540	COG5265	(ABC) transporter
AVCG412_22545	COG2205	protein histidine kinase activity
AVCG412_22550	COG0745	RESPONSE REGULATOR receiver
AVCG412_22570	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVCG412_22575	COG1845	cytochrome c oxidase, subunit III
AVCG412_22580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVCG412_22590	COG1595	DNA-templated transcription, initiation
AVCG412_22600	COG0670	Belongs to the BI1 family
AVCG412_22615	COG2273	Hydrolase Family 16
AVCG412_22615	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AVCG412_22620	COG1301	dicarboxylic acid transport
AVCG412_22625	COG4191	Histidine kinase
AVCG412_22630	COG2204	response regulator
AVCG412_22635	COG1309	transcriptional regulator
AVCG412_22650	COG1940	carbohydrate kinase activity
AVCG412_22655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AVCG412_22660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVCG412_22665	COG2188	Transcriptional regulator
AVCG412_22680	COG0395	ABC-type sugar transport system, permease component
AVCG412_22690	COG3842	ATPase activity
AVCG412_22715	COG0837	glucose binding
AVCG412_22715	COG1737	Transcriptional regulator
AVCG412_22720	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_22735	COG2814	Major facilitator Superfamily
AVCG412_22740	COG3142	Participates in the control of copper homeostasis
AVCG412_22760	COG0642	Histidine kinase
AVCG412_22780	COG4952	isomerase
AVCG412_22785	COG3347	Dehydrogenase
AVCG412_22785	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG412_22800	COG1129	ABC transporter
AVCG412_22810	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_22815	COG3254	rhamnose metabolic process
AVCG412_22820	COG1070	Carbohydrate kinase
AVCG412_22830	COG5001	Diguanylate cyclase
AVCG412_22845	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_22855	COG3842	ATPase activity
AVCG412_22875	COG2094	Belongs to the DNA glycosylase MPG family
AVCG412_22880	COG4181	ATPase activity
AVCG412_22885	COG0577	efflux transmembrane transporter activity
AVCG412_22895	COG4303	Ethanolamine ammonia lyase large subunit
AVCG412_22900	COG4302	ethanolamine ammonia-lyase activity
AVCG412_22905	COG1192	Involved in chromosome partitioning
AVCG412_22910	COG1475	DNA binding
AVCG412_22915	COG0640	Transcriptional regulator
AVCG412_22920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AVCG412_22925	COG3177	Filamentation induced by cAMP protein fic
AVCG412_22975	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG412_22980	COG1129	ABC transporter
AVCG412_23010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_23015	COG0601	transmembrane transport
AVCG412_23025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_23030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG412_23035	COG0583	DNA-binding transcription factor activity
AVCG412_23050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVCG412_23065	COG1132	(ABC) transporter
AVCG412_23075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_23085	COG0747	negative chemotaxis
AVCG412_23095	COG1082	Xylose isomerase domain protein TIM barrel
AVCG412_23100	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVCG412_23105	COG0019	diaminopimelate decarboxylase activity
AVCG412_23115	COG1475	DNA binding
AVCG412_23125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVCG412_23135	COG0436	Aminotransferase
AVCG412_23180	COG1475	DNA binding
AVCG412_23185	COG4974	Belongs to the 'phage' integrase family
AVCG412_23195	COG0582	viral genome integration into host DNA
AVCG412_23200	COG4974	Belongs to the 'phage' integrase family
AVCG412_23215	COG5489	Protein of unknown function (DUF736)
AVCG412_23335	COG3158	transport of potassium into the cell
AVCG412_23420	COG1192	Involved in chromosome partitioning
AVCG412_23430	COG3843	relaxase mobilization nuclease domain protein
AVCG412_23440	COG3505	Type IV secretory pathway VirD4
AVCG412_23500	COG2963	transposase activity
AVCG412_23510	COG4372	Transposase
AVCG412_23540	COG4372	Transposase
AVCG412_23550	COG2963	transposase activity
AVCG412_23560	COG4172	Belongs to the ABC transporter superfamily
AVCG412_23565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_23570	COG0601	transmembrane transport
AVCG412_23590	COG0010	Belongs to the arginase family
AVCG412_23650	COG1283	sodium-dependent phosphate transmembrane transporter activity
AVCG412_23655	COG0483	inositol monophosphate 1-phosphatase activity
AVCG412_23660	COG0584	glycerophosphoryl diester phosphodiesterase
AVCG412_23670	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG412_23680	COG3842	ATPase activity
AVCG412_23710	COG0154	amidase activity
AVCG412_23715	COG1231	oxidoreductase activity
AVCG412_23745	COG4372	Transposase
AVCG412_23755	COG2963	transposase activity
AVCG412_23785	COG1228	amidohydrolase
AVCG412_23795	COG1177	transmembrane transport
AVCG412_23805	COG3842	ATPase activity
AVCG412_23825	COG2986	histidine ammonia-lyase
AVCG412_23850	COG0765	amino acid transport
AVCG412_23865	COG2079	MmgE PrpD family protein
AVCG412_23870	COG0583	DNA-binding transcription factor activity
AVCG412_23880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AVCG412_23945	COG0584	glycerophosphoryl diester phosphodiesterase
AVCG412_23955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG412_23970	COG0444	Belongs to the ABC transporter superfamily
AVCG412_23990	COG1126	abc transporter atp-binding protein
AVCG412_24010	COG3701	Conjugal transfer protein
AVCG412_24015	COG3846	protein secretion by the type IV secretion system
AVCG412_24025	COG5314	conjugation
AVCG412_24030	COG3451	type IV secretory pathway VirB4
AVCG412_24045	COG4962	Type ii secretion system protein e