locus-tag	class	description
AVCG678_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AVCG678_00010	COG0697	spore germination
AVCG678_00015	COG2226	methyltransferase
AVCG678_00020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVCG678_00025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AVCG678_00035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AVCG678_00040	COG1420	regulation of RNA biosynthetic process
AVCG678_00045	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AVCG678_00050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVCG678_00055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AVCG678_00065	COG1137	ATPase activity
AVCG678_00070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AVCG678_00080	COG0776	regulation of translation
AVCG678_00090	COG0116	Belongs to the methyltransferase superfamily
AVCG678_00090	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AVCG678_00095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVCG678_00100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AVCG678_00115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AVCG678_00120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AVCG678_00130	COG0346	lactoylglutathione lyase activity
AVCG678_00135	COG0180	Tryptophanyl-tRNA synthetase
AVCG678_00145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AVCG678_00150	COG1214	PFAM Peptidase M22, glycoprotease
AVCG678_00170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVCG678_00175	COG1702	phosphate starvation-inducible protein PhoH
AVCG678_00180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AVCG678_00185	COG4535	Mg2 and Co2 transporter CorC
AVCG678_00190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AVCG678_00195	COG1396	sequence-specific DNA binding
AVCG678_00200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AVCG678_00205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AVCG678_00215	COG0071	Belongs to the small heat shock protein (HSP20) family
AVCG678_00235	COG0840	transmembrane signaling receptor activity
AVCG678_00245	COG2205	protein histidine kinase activity
AVCG678_00250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AVCG678_00255	COG0594	ribonuclease P activity
AVCG678_00260	COG0706	membrane insertase activity
AVCG678_00265	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AVCG678_00270	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AVCG678_00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AVCG678_00290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG678_00305	COG1749	Flagellar hook protein flgE
AVCG678_00315	COG2171	N-acyltransferase activity
AVCG678_00320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG678_00345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AVCG678_00350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AVCG678_00360	COG0745	RESPONSE REGULATOR receiver
AVCG678_00365	COG0704	Plays a role in the regulation of phosphate uptake
AVCG678_00370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVCG678_00380	COG0573	inorganic phosphate transmembrane transporter activity
AVCG678_00390	COG5002	protein histidine kinase activity
AVCG678_00395	COG2326	polyphosphate kinase activity
AVCG678_00415	COG1125	glycine betaine transport
AVCG678_00415	COG0517	IMP dehydrogenase activity
AVCG678_00435	COG2188	Transcriptional regulator
AVCG678_00440	COG2986	histidine ammonia-lyase
AVCG678_00450	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AVCG678_00455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AVCG678_00455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AVCG678_00465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AVCG678_00485	COG0427	acetyl-CoA hydrolase
AVCG678_00495	COG3938	Belongs to the proline racemase family
AVCG678_00500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG678_00505	COG0745	RESPONSE REGULATOR receiver
AVCG678_00525	COG0418	dihydroorotase activity
AVCG678_00530	COG3706	GGDEF domain
AVCG678_00535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVCG678_00545	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_00550	COG0166	Belongs to the GPI family
AVCG678_00555	COG0318	PFAM AMP-dependent synthetase and ligase
AVCG678_00580	COG0101	tRNA pseudouridine synthase activity
AVCG678_00585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AVCG678_00590	COG0242	peptide deformylase activity
AVCG678_00595	COG2967	ApaG domain
AVCG678_00605	COG0717	Belongs to the dCTP deaminase family
AVCG678_00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_00655	COG0167	dihydroorotate dehydrogenase activity
AVCG678_00695	COG1024	Enoyl-CoA hydratase
AVCG678_00695	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVCG678_00700	COG0183	Belongs to the thiolase family
AVCG678_00705	COG1960	acyl-CoA dehydrogenase activity
AVCG678_00725	COG1785	Belongs to the alkaline phosphatase family
AVCG678_00735	COG1136	(ABC) transporter
AVCG678_00750	COG2203	Gaf domain
AVCG678_00750	COG3706	GGDEF domain
AVCG678_00750	COG4251	negative regulation of phosphorylation
AVCG678_00750	COG5001	Diguanylate cyclase
AVCG678_00755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AVCG678_00765	COG1201	RNA secondary structure unwinding
AVCG678_00785	COG1047	Peptidyl-prolyl cis-trans
AVCG678_00790	COG2205	protein histidine kinase activity
AVCG678_00790	COG2198	Histidine kinase
AVCG678_00790	COG0784	Response regulator, receiver
AVCG678_00795	COG1970	mechanosensitive ion channel activity
AVCG678_00800	COG0436	Aminotransferase
AVCG678_00805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVCG678_00825	COG1216	Glycosyl transferase, family 2
AVCG678_00850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AVCG678_00855	COG0424	maF-like protein
AVCG678_00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AVCG678_00870	COG5328	Belongs to the UPF0262 family
AVCG678_00875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AVCG678_00885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AVCG678_00920	COG1215	transferase activity, transferring glycosyl groups
AVCG678_00930	COG0488	(ABC) transporter
AVCG678_00955	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVCG678_00960	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVCG678_00965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVCG678_00970	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AVCG678_00975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AVCG678_00980	COG4786	Flagellar basal body rod
AVCG678_00985	COG1157	protein secretion by the type III secretion system
AVCG678_00995	COG1815	bacterial-type flagellum-dependent cell motility
AVCG678_01000	COG1558	bacterial-type flagellum-dependent cell motility
AVCG678_01005	COG1677	Flagellar hook-basal body complex protein FliE
AVCG678_01010	COG4786	Flagellar basal body rod
AVCG678_01015	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AVCG678_01020	COG1706	bacterial-type flagellum-dependent cell motility
AVCG678_01030	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AVCG678_01040	COG1338	Plays a role in the flagellum-specific transport system
AVCG678_01045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_01050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_01060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_01065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_01070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_01080	COG1360	Flagellar Motor Protein
AVCG678_01105	COG1749	Flagellar hook protein flgE
AVCG678_01125	COG5443	negative regulation of bacterial-type flagellum assembly
AVCG678_01130	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AVCG678_01135	COG4794	Type iii secretion
AVCG678_01140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AVCG678_01175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AVCG678_01180	COG1609	Transcriptional regulator
AVCG678_01185	COG1653	transport
AVCG678_01190	COG1175	transmembrane transport
AVCG678_01195	COG0395	ABC-type sugar transport system, permease component
AVCG678_01200	COG0366	Alpha amylase catalytic
AVCG678_01205	COG3842	ATPase activity
AVCG678_01225	COG3493	citrate carrier protein
AVCG678_01235	COG0129	dihydroxy-acid dehydratase activity
AVCG678_01240	COG0363	glucosamine-6-phosphate deaminase activity
AVCG678_01245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AVCG678_01250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_01260	COG2081	HI0933 family
AVCG678_01275	COG0840	transmembrane signaling receptor activity
AVCG678_01275	COG2972	Histidine kinase
AVCG678_01280	COG0583	DNA-binding transcription factor activity
AVCG678_01305	COG2224	Isocitrate lyase
AVCG678_01320	COG3842	ATPase activity
AVCG678_01325	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_01330	COG1177	transmembrane transport
AVCG678_01340	COG2205	protein histidine kinase activity
AVCG678_01390	COG1959	2 iron, 2 sulfur cluster binding
AVCG678_01395	COG3265	gluconokinase activity
AVCG678_01400	COG2134	cdp-diacylglycerol pyrophosphatase
AVCG678_01405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_01410	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVCG678_01430	COG0579	oxidoreductase
AVCG678_01460	COG0248	Ppx GppA phosphatase
AVCG678_01465	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AVCG678_01475	COG5001	Diguanylate cyclase
AVCG678_01475	COG3300	MHYT domain
AVCG678_01480	COG5002	protein histidine kinase activity
AVCG678_01480	COG2198	Histidine kinase
AVCG678_01480	COG0784	Response regulator, receiver
AVCG678_01485	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AVCG678_01495	COG1663	tetraacyldisaccharide 4'-kinase activity
AVCG678_01505	COG1519	Transferase
AVCG678_01520	COG0312	modulator of DNA gyrase
AVCG678_01525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AVCG678_01525	COG0475	glutathione-regulated potassium exporter activity
AVCG678_01535	COG0742	ribosomal rna small subunit methyltransferase
AVCG678_01540	COG1187	pseudouridine synthase activity
AVCG678_01545	COG0590	tRNA wobble adenosine to inosine editing
AVCG678_01555	COG0477	Major facilitator Superfamily
AVCG678_01565	COG3386	PFAM SMP-30 Gluconolaconase
AVCG678_01570	COG2771	luxR family
AVCG678_01590	COG3158	transport of potassium into the cell
AVCG678_01600	COG0356	it plays a direct role in the translocation of protons across the membrane
AVCG678_01610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVCG678_01615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AVCG678_01620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AVCG678_01635	COG0521	Mo-molybdopterin cofactor biosynthetic process
AVCG678_01640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AVCG678_01650	COG0142	geranyltranstransferase activity
AVCG678_01660	COG4106	trans-aconitate 2-methyltransferase activity
AVCG678_01680	COG0752	glycyl-tRNA synthetase alpha subunit
AVCG678_01690	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AVCG678_01695	COG0751	glycine-tRNA ligase activity
AVCG678_01700	COG1683	Conserved Protein
AVCG678_01705	COG0840	transmembrane signaling receptor activity
AVCG678_01705	COG0840	transmembrane signaling receptor activity
AVCG678_01715	COG0151	Belongs to the GarS family
AVCG678_01725	COG2183	response to ionizing radiation
AVCG678_01730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG678_01735	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AVCG678_01760	COG0725	ABC transporter, periplasmic molybdate-binding protein
AVCG678_01765	COG4149	molybdate abc transporter
AVCG678_01770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AVCG678_01790	COG0009	L-threonylcarbamoyladenylate synthase
AVCG678_01800	COG0840	transmembrane signaling receptor activity
AVCG678_01805	COG4638	Rieske (2fe-2S)
AVCG678_01830	COG1960	acyl-CoA dehydrogenase activity
AVCG678_01835	COG1024	Enoyl-CoA hydratase
AVCG678_01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AVCG678_01855	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AVCG678_01860	COG0840	transmembrane signaling receptor activity
AVCG678_01865	COG0840	transmembrane signaling receptor activity
AVCG678_01870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AVCG678_01875	COG1722	exodeoxyribonuclease VII activity
AVCG678_01880	COG0123	including yeast histone deacetylase and acetoin utilization protein
AVCG678_01890	COG1268	BioY protein
AVCG678_01895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AVCG678_01900	COG1122	ATPase activity
AVCG678_01910	COG3214	Protein conserved in bacteria
AVCG678_01930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVCG678_01930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AVCG678_01935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AVCG678_01940	COG3300	MHYT domain
AVCG678_01940	COG5001	Diguanylate cyclase
AVCG678_01955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVCG678_01960	COG0484	heat shock protein binding
AVCG678_01970	COG0259	pyridoxamine-phosphate oxidase activity
AVCG678_01980	COG2814	Major facilitator Superfamily
AVCG678_01985	COG0789	Transcriptional regulator
AVCG678_01990	COG1686	Belongs to the peptidase S11 family
AVCG678_02005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG678_02015	COG0312	modulator of DNA gyrase
AVCG678_02030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVCG678_02035	COG0109	protoheme IX farnesyltransferase activity
AVCG678_02045	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AVCG678_02060	COG3346	SURF1 family
AVCG678_02070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AVCG678_02085	COG1280	lysine exporter protein (LysE YggA)
AVCG678_02090	COG0436	Aminotransferase
AVCG678_02100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AVCG678_02105	COG0328	RNA-DNA hybrid ribonuclease activity
AVCG678_02115	COG0803	Belongs to the bacterial solute-binding protein 9 family
AVCG678_02130	COG0678	peroxiredoxin activity
AVCG678_02130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVCG678_02140	COG1678	Uncharacterized ACR, COG1678
AVCG678_02150	COG0640	Transcriptional regulator
AVCG678_02155	COG5001	Diguanylate cyclase
AVCG678_02160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVCG678_02165	COG0612	Peptidase, M16
AVCG678_02180	COG1597	lipid kinase activity
AVCG678_02185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG678_02200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AVCG678_02230	COG1194	a g-specific adenine glycosylase
AVCG678_02245	COG1196	nuclear chromosome segregation
AVCG678_02255	COG2814	Major facilitator Superfamily
AVCG678_02270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AVCG678_02270	COG0574	Belongs to the PEP-utilizing enzyme family
AVCG678_02305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG678_02325	COG0840	transmembrane signaling receptor activity
AVCG678_02330	COG0175	sulfate reduction
AVCG678_02335	COG0175	sulfate reduction
AVCG678_02340	COG2895	sulfate adenylyltransferase (ATP) activity
AVCG678_02360	COG1609	Transcriptional regulator
AVCG678_02370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG678_02380	COG0693	protein deglycase activity
AVCG678_02400	COG0038	chloride channel
AVCG678_02405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_02430	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AVCG678_02435	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_02440	COG0625	glutathione transferase activity
AVCG678_02445	COG3119	arylsulfatase activity
AVCG678_02450	COG1309	transcriptional regulator
AVCG678_02455	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AVCG678_02470	COG0840	transmembrane signaling receptor activity
AVCG678_02475	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
AVCG678_02495	COG1349	DNA-binding transcription factor activity
AVCG678_02560	COG1280	lysine exporter protein (LysE YggA)
AVCG678_02565	COG0778	Nitroreductase
AVCG678_02590	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG678_02590	COG1388	LysM domain
AVCG678_02595	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG678_02600	COG1846	Transcriptional regulator
AVCG678_02605	COG1764	response to oxidative stress
AVCG678_02620	COG4191	Histidine kinase
AVCG678_02620	COG0784	Response regulator, receiver
AVCG678_02625	COG3265	gluconokinase activity
AVCG678_02630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AVCG678_02640	COG0840	transmembrane signaling receptor activity
AVCG678_02645	COG0840	transmembrane signaling receptor activity
AVCG678_02655	COG0433	COG0433 Predicted ATPase
AVCG678_02660	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVCG678_02670	COG0840	transmembrane signaling receptor activity
AVCG678_02675	COG1968	undecaprenyl-diphosphatase activity
AVCG678_02685	COG4214	carbohydrate transport
AVCG678_02690	COG4213	ABC transporter substrate-binding protein
AVCG678_02695	COG1940	carbohydrate kinase activity
AVCG678_02695	COG1846	Transcriptional regulator
AVCG678_02715	COG1120	ATPase activity
AVCG678_02720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG678_02735	COG2226	methyltransferase
AVCG678_02760	COG2010	Cytochrome c
AVCG678_02780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVCG678_02790	COG1733	regulation of RNA biosynthetic process
AVCG678_02800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AVCG678_02810	COG3447	MASE1 domain protein
AVCG678_02810	COG5001	Diguanylate cyclase
AVCG678_02810	COG5002	protein histidine kinase activity
AVCG678_02815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG678_02855	COG2514	catechol 2,3-dioxygenase activity
AVCG678_02870	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AVCG678_02875	COG1272	protein, Hemolysin III
AVCG678_02880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG678_02900	COG4957	zinc ion binding
AVCG678_02905	COG1320	monovalent cation:proton antiporter activity
AVCG678_02910	COG2212	antiporter activity
AVCG678_02915	COG1863	multisubunit Na H antiporter MnhE subunit
AVCG678_02920	COG0651	ATP synthesis coupled electron transport
AVCG678_02925	COG1006	Multisubunit Na H antiporter MnhC subunit
AVCG678_02930	COG2111	Na H antiporter
AVCG678_02935	COG2111	Na H antiporter
AVCG678_02935	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVCG678_02940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVCG678_02965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG678_02970	COG1136	(ABC) transporter
AVCG678_02970	COG0577	efflux transmembrane transporter activity
AVCG678_02990	COG2166	iron-sulfur cluster assembly
AVCG678_03000	COG2205	protein histidine kinase activity
AVCG678_03015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG678_03085	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVCG678_03090	COG2983	Belongs to the UPF0260 family
AVCG678_03105	COG0789	Transcriptional regulator
AVCG678_03130	COG4695	Portal protein
AVCG678_03235	COG4520	surface antigen
AVCG678_03240	COG4235	cytochrome complex assembly
AVCG678_03245	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AVCG678_03250	COG1138	Cytochrome C-type biogenesis protein
AVCG678_03255	COG3088	subunit of a heme lyase
AVCG678_03265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVCG678_03270	COG0745	RESPONSE REGULATOR receiver
AVCG678_03275	COG2205	protein histidine kinase activity
AVCG678_03280	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AVCG678_03285	COG2202	Pas domain
AVCG678_03285	COG2205	protein histidine kinase activity
AVCG678_03290	COG0308	aminopeptidase N
AVCG678_03295	COG0840	transmembrane signaling receptor activity
AVCG678_03295	COG3290	protein histidine kinase activity
AVCG678_03330	COG0443	Heat shock 70 kDa protein
AVCG678_03345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG678_03360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG678_03365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG678_03380	COG2239	Acts as a magnesium transporter
AVCG678_03385	COG2814	Major facilitator Superfamily
AVCG678_03400	COG4172	Belongs to the ABC transporter superfamily
AVCG678_03405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_03410	COG0601	transmembrane transport
AVCG678_03415	COG4166	transmembrane transport
AVCG678_03420	COG0174	glutamine synthetase
AVCG678_03435	COG1695	Transcriptional regulator
AVCG678_03440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVCG678_03445	COG0463	Glycosyl transferase, family 2
AVCG678_03455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AVCG678_03465	COG0625	glutathione transferase activity
AVCG678_03480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVCG678_03520	COG0741	lytic transglycosylase activity
AVCG678_03525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_03530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AVCG678_03540	COG2169	Transcriptional regulator
AVCG678_03540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVCG678_03545	COG0840	transmembrane signaling receptor activity
AVCG678_03555	COG1758	RNA polymerase activity
AVCG678_03570	COG0681	Belongs to the peptidase S26 family
AVCG678_03575	COG0571	ribonuclease III activity
AVCG678_03580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AVCG678_03585	COG3180	Ammonia monooxygenase
AVCG678_03590	COG1381	Involved in DNA repair and RecF pathway recombination
AVCG678_03605	COG1418	mRNA catabolic process
AVCG678_03620	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AVCG678_03645	COG1051	belongs to the nudix hydrolase family
AVCG678_03660	COG1183	phosphatidylcholine synthase activity
AVCG678_03665	COG0688	phosphatidylethanolamine metabolic process
AVCG678_03670	COG5265	(ABC) transporter
AVCG678_03675	COG1652	LysM domain
AVCG678_03675	COG2823	Periplasmic or secreted lipoprotein
AVCG678_03685	COG2962	Rard protein
AVCG678_03690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVCG678_03725	COG0215	cysteine-tRNA ligase activity
AVCG678_03730	COG5434	Belongs to the glycosyl hydrolase 28 family
AVCG678_03735	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AVCG678_03740	COG1088	dTDP-glucose 4,6-dehydratase activity
AVCG678_03745	COG1091	dTDP-4-dehydrorhamnose reductase activity
AVCG678_03750	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AVCG678_03765	COG4221	oxidoreductase activity
AVCG678_03770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVCG678_03775	COG1286	toxin biosynthetic process
AVCG678_03780	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AVCG678_03785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AVCG678_03800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVCG678_03805	COG1917	Cupin 2, conserved barrel domain protein
AVCG678_03805	COG2207	Transcriptional regulator
AVCG678_03810	COG0765	amino acid transport
AVCG678_03815	COG0765	amino acid transport
AVCG678_03825	COG0305	Participates in initiation and elongation during chromosome replication
AVCG678_03830	COG0359	binds to the 23S rRNA
AVCG678_03840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AVCG678_03845	COG0360	Binds together with S18 to 16S ribosomal RNA
AVCG678_03865	COG0667	Aldo Keto reductase
AVCG678_03870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVCG678_03880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG678_03885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVCG678_03890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AVCG678_03895	COG1561	YicC-like family, N-terminal region
AVCG678_03900	COG0194	GDP metabolic process
AVCG678_03905	COG0500	methyltransferase
AVCG678_03910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AVCG678_03915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AVCG678_03930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AVCG678_03945	COG0671	phosphoesterase, PA-phosphatase related
AVCG678_03950	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVCG678_03960	COG0840	transmembrane signaling receptor activity
AVCG678_03965	COG0488	(ABC) transporter
AVCG678_03975	COG0105	UTP biosynthetic process
AVCG678_03980	COG0314	molybdopterin synthase activity
AVCG678_03990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AVCG678_03995	COG0322	excinuclease ABC activity
AVCG678_04000	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_04010	COG0625	glutathione transferase activity
AVCG678_04015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AVCG678_04020	COG0243	molybdopterin cofactor binding
AVCG678_04030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG678_04030	COG3453	Protein conserved in bacteria
AVCG678_04035	COG0640	Transcriptional regulator
AVCG678_04050	COG0730	response to heat
AVCG678_04055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AVCG678_04060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AVCG678_04065	COG0628	permease
AVCG678_04075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AVCG678_04080	COG0248	Ppx GppA phosphatase
AVCG678_04085	COG1321	iron dependent repressor
AVCG678_04090	COG1914	H( )-stimulated, divalent metal cation uptake system
AVCG678_04110	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AVCG678_04125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AVCG678_04140	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AVCG678_04145	COG3300	MHYT domain
AVCG678_04145	COG5001	Diguanylate cyclase
AVCG678_04155	COG2200	EAL domain
AVCG678_04155	COG2203	Gaf domain
AVCG678_04155	COG2199	diguanylate cyclase activity
AVCG678_04160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AVCG678_04170	COG0113	porphobilinogen synthase activity
AVCG678_04190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AVCG678_04195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AVCG678_04200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVCG678_04200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AVCG678_04215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVCG678_04220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVCG678_04225	COG2814	Major facilitator Superfamily
AVCG678_04230	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AVCG678_04250	COG0416	fatty acid biosynthetic process
AVCG678_04255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AVCG678_04260	COG0776	regulation of translation
AVCG678_04315	COG1982	Orn Lys Arg decarboxylase major
AVCG678_04330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVCG678_04405	COG1612	heme a metabolic process
AVCG678_04410	COG3384	dioxygenase
AVCG678_04420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AVCG678_04425	COG0010	Belongs to the arginase family
AVCG678_04440	COG2329	Antibiotic biosynthesis monooxygenase
AVCG678_04445	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AVCG678_04450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AVCG678_04455	COG1832	CoA-binding protein
AVCG678_04465	COG1832	CoA-binding protein
AVCG678_04475	COG1408	metallophosphoesterase
AVCG678_04485	COG2124	cytochrome p450
AVCG678_04495	COG0740	serine-type endopeptidase activity
AVCG678_04500	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AVCG678_04505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVCG678_04535	COG1024	Enoyl-CoA hydratase
AVCG678_04555	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG678_04560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG678_04565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG678_04570	COG0649	NAD binding
AVCG678_04580	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AVCG678_04585	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AVCG678_04590	COG0052	Belongs to the universal ribosomal protein uS2 family
AVCG678_04600	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AVCG678_04605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AVCG678_04615	COG0713	ATP synthesis coupled electron transport
AVCG678_04630	COG1007	ATP synthesis coupled electron transport
AVCG678_04645	COG0346	lactoylglutathione lyase activity
AVCG678_04650	COG0251	oxidation-reduction process
AVCG678_04665	COG0442	prolyl-tRNA aminoacylation
AVCG678_04675	COG1136	(ABC) transporter
AVCG678_04690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AVCG678_04705	COG0784	Response regulator, receiver
AVCG678_04715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AVCG678_04720	COG0477	Major facilitator Superfamily
AVCG678_04730	COG0557	exoribonuclease II activity
AVCG678_04735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AVCG678_04735	COG1754	DNA topoisomerase type I activity
AVCG678_04745	COG0758	DNA mediated transformation
AVCG678_04750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AVCG678_04760	COG0540	Belongs to the ATCase OTCase family
AVCG678_04765	COG1960	acyl-CoA dehydrogenase activity
AVCG678_04785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AVCG678_04790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVCG678_04795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVCG678_04800	COG0154	amidase activity
AVCG678_04815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AVCG678_04820	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG678_04820	COG3952	Lipid A Biosynthesis
AVCG678_04825	COG0463	Glycosyl transferase, family 2
AVCG678_04830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AVCG678_04850	COG4765	Protein conserved in bacteria
AVCG678_04855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AVCG678_04865	COG0511	ligase activity, forming carbon-carbon bonds
AVCG678_04870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVCG678_04875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AVCG678_04880	COG0436	Aminotransferase
AVCG678_04890	COG1530	ribonuclease E activity
AVCG678_04895	COG0860	N-Acetylmuramoyl-L-alanine amidase
AVCG678_04900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AVCG678_04910	COG0284	orotidine-5'-phosphate decarboxylase activity
AVCG678_04920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AVCG678_04940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVCG678_04960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVCG678_04985	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AVCG678_04995	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AVCG678_05000	COG0081	regulation of translation
AVCG678_05005	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AVCG678_05010	COG0222	ribosome binding
AVCG678_05015	COG0085	RNA polymerase activity
AVCG678_05020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AVCG678_05035	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AVCG678_05040	COG0049	tRNA binding
AVCG678_05045	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AVCG678_05050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AVCG678_05055	COG0051	transcription antitermination factor activity, RNA binding
AVCG678_05060	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AVCG678_05065	COG0088	Forms part of the polypeptide exit tunnel
AVCG678_05070	COG0089	rRNA binding
AVCG678_05075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AVCG678_05080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AVCG678_05085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AVCG678_05090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AVCG678_05095	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AVCG678_05100	COG0255	Belongs to the universal ribosomal protein uL29 family
AVCG678_05105	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AVCG678_05110	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AVCG678_05115	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AVCG678_05120	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AVCG678_05125	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AVCG678_05130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AVCG678_05135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AVCG678_05140	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AVCG678_05145	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AVCG678_05150	COG1841	ribosomal large subunit assembly
AVCG678_05155	COG0200	Binds to the 23S rRNA
AVCG678_05160	COG0201	protein transport
AVCG678_05165	COG0563	adenylate kinase activity
AVCG678_05170	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AVCG678_05175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AVCG678_05180	COG0202	RNA polymerase activity
AVCG678_05185	COG0203	ribosomal protein L17
AVCG678_05200	COG2897	thiosulfate sulfurtransferase activity
AVCG678_05210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AVCG678_05215	COG0415	Belongs to the DNA photolyase family
AVCG678_05225	COG0739	heme binding
AVCG678_05230	COG2833	Protein of unknown function (DUF455)
AVCG678_05235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AVCG678_05260	COG0281	malic enzyme
AVCG678_05260	COG0280	phosphate acetyltransferase
AVCG678_05270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AVCG678_05275	COG1127	ABC transporter
AVCG678_05285	COG3218	ABC-type transport auxiliary lipoprotein component
AVCG678_05285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AVCG678_05290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVCG678_05310	COG0047	phosphoribosylformylglycinamidine synthase activity
AVCG678_05315	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVCG678_05320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVCG678_05335	COG3706	GGDEF domain
AVCG678_05345	COG0538	isocitrate dehydrogenase activity
AVCG678_05350	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AVCG678_05355	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AVCG678_05365	COG1253	flavin adenine dinucleotide binding
AVCG678_05375	COG0657	acetylesterase activity
AVCG678_05375	COG2755	lipolytic protein G-D-S-L family
AVCG678_05380	COG2195	Cleaves the N-terminal amino acid of tripeptides
AVCG678_05395	COG0861	Integral membrane protein TerC family
AVCG678_05400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AVCG678_05405	COG2066	Belongs to the glutaminase family
AVCG678_05415	COG0037	tRNA processing
AVCG678_05420	COG0483	inositol monophosphate 1-phosphatase activity
AVCG678_05425	COG0483	inositol monophosphate 1-phosphatase activity
AVCG678_05430	COG2814	Major facilitator Superfamily
AVCG678_05435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AVCG678_05450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AVCG678_05455	COG0484	heat shock protein binding
AVCG678_05470	COG0321	lipoyl(octanoyl) transferase activity
AVCG678_05500	COG1396	sequence-specific DNA binding
AVCG678_05535	COG0250	Participates in transcription elongation, termination and antitermination
AVCG678_05725	COG0463	Glycosyl transferase, family 2
AVCG678_05725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AVCG678_05750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AVCG678_05755	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AVCG678_05785	COG0242	peptide deformylase activity
AVCG678_05800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AVCG678_05805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG678_05810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVCG678_05815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVCG678_05820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AVCG678_05845	COG0823	Involved in the tonB-independent uptake of proteins
AVCG678_05850	COG0778	Nitroreductase
AVCG678_05860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AVCG678_05865	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AVCG678_05885	COG2205	protein histidine kinase activity
AVCG678_05885	COG2202	Pas domain
AVCG678_05895	COG1573	uracil-dna glycosylase
AVCG678_05900	COG1522	sequence-specific DNA binding
AVCG678_05905	COG2084	Dehydrogenase
AVCG678_05910	COG2267	carboxylic ester hydrolase activity
AVCG678_05920	COG5425	PFAM Usg family protein
AVCG678_05945	COG1763	Mo-molybdopterin cofactor biosynthetic process
AVCG678_05950	COG0746	molybdenum cofactor guanylyltransferase activity
AVCG678_05960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVCG678_05970	COG3706	GGDEF domain
AVCG678_05985	COG0114	fumarate hydratase activity
AVCG678_05990	COG2989	Protein conserved in bacteria
AVCG678_05995	COG0546	phosphoglycolate phosphatase activity
AVCG678_06000	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AVCG678_06015	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AVCG678_06055	COG3706	GGDEF domain
AVCG678_06055	COG2203	Gaf domain
AVCG678_06055	COG5001	Diguanylate cyclase
AVCG678_06055	COG4251	negative regulation of phosphorylation
AVCG678_06060	COG0556	nucleotide-excision repair
AVCG678_06080	COG3161	chorismate lyase activity
AVCG678_06090	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AVCG678_06095	COG0148	phosphopyruvate hydratase activity
AVCG678_06105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AVCG678_06110	COG0022	dehydrogenase e1 component
AVCG678_06110	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVCG678_06115	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVCG678_06130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AVCG678_06140	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AVCG678_06160	COG0477	Major facilitator Superfamily
AVCG678_06165	COG2867	negative regulation of translational initiation
AVCG678_06175	COG1058	Belongs to the CinA family
AVCG678_06175	COG1546	Belongs to the CinA family
AVCG678_06180	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AVCG678_06180	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AVCG678_06190	COG3852	Histidine kinase
AVCG678_06195	COG2204	response regulator
AVCG678_06200	COG5000	phosphorelay sensor kinase activity
AVCG678_06205	COG2204	response regulator
AVCG678_06210	COG1923	regulation of RNA biosynthetic process
AVCG678_06215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AVCG678_06225	COG3956	TIGRFAM MazG family protein
AVCG678_06235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AVCG678_06235	COG1648	precorrin-2 dehydrogenase activity
AVCG678_06260	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_06270	COG1686	Belongs to the peptidase S11 family
AVCG678_06275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVCG678_06285	COG0730	response to heat
AVCG678_06290	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVCG678_06295	COG0084	hydrolase, TatD family'
AVCG678_06300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AVCG678_06300	COG0321	lipoyl(octanoyl) transferase activity
AVCG678_06315	COG0785	Cytochrome C biogenesis protein
AVCG678_06320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG678_06325	COG1183	phosphatidylcholine synthase activity
AVCG678_06330	COG3845	ABC transporter
AVCG678_06340	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_06355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVCG678_06360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVCG678_06380	COG1177	transmembrane transport
AVCG678_06385	COG4149	molybdate abc transporter
AVCG678_06390	COG3842	ATPase activity
AVCG678_06400	COG1940	carbohydrate kinase activity
AVCG678_06405	COG0523	cobalamin synthesis protein
AVCG678_06415	COG1121	(ABC) transporter
AVCG678_06420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AVCG678_06425	COG0735	belongs to the Fur family
AVCG678_06445	COG1686	Belongs to the peptidase S11 family
AVCG678_06480	COG1752	Esterase of the alpha-beta hydrolase superfamily
AVCG678_06485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AVCG678_06490	COG0302	gtp cyclohydrolase
AVCG678_06500	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AVCG678_06505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AVCG678_06520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AVCG678_06525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVCG678_06570	COG0187	DNA topoisomerase II activity
AVCG678_06585	COG0149	triose-phosphate isomerase activity
AVCG678_06595	COG0504	CTP synthase activity
AVCG678_06620	COG0633	Ferredoxin
AVCG678_06630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AVCG678_06660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVCG678_06660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AVCG678_06665	COG0509	glycine decarboxylation via glycine cleavage system
AVCG678_06670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG678_06690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AVCG678_06695	COG0564	pseudouridine synthase activity
AVCG678_06700	COG0546	phosphoglycolate phosphatase activity
AVCG678_06715	COG0477	Major facilitator Superfamily
AVCG678_06730	COG2003	Belongs to the UPF0758 family
AVCG678_06735	COG0024	Methionine aminopeptidase
AVCG678_06740	COG0583	DNA-binding transcription factor activity
AVCG678_06745	COG2855	membrane
AVCG678_06750	COG1489	DNA binding
AVCG678_06755	COG3243	poly(R)-hydroxyalkanoic acid synthase
AVCG678_06765	COG0436	Aminotransferase
AVCG678_06775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AVCG678_06800	COG0346	lactoylglutathione lyase activity
AVCG678_06805	COG1278	Cold shock
AVCG678_06895	COG0629	single-stranded DNA binding
AVCG678_07220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AVCG678_07230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AVCG678_07235	COG1280	lysine exporter protein (LysE YggA)
AVCG678_07245	COG0697	spore germination
AVCG678_07275	COG0174	glutamine synthetase
AVCG678_07280	COG0347	Belongs to the P(II) protein family
AVCG678_07285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AVCG678_07285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AVCG678_07300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AVCG678_07305	COG0629	single-stranded DNA binding
AVCG678_07315	COG2095	MarC family integral membrane protein
AVCG678_07325	COG2217	Heavy metal translocating P-type atpase
AVCG678_07350	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AVCG678_07365	COG1653	transport
AVCG678_07370	COG1175	transmembrane transport
AVCG678_07375	COG0395	ABC-type sugar transport system, permease component
AVCG678_07380	COG3842	ATPase activity
AVCG678_07400	COG0667	Aldo Keto reductase
AVCG678_07405	COG3507	Belongs to the glycosyl hydrolase 43 family
AVCG678_07420	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AVCG678_07425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AVCG678_07430	COG0129	dihydroxy-acid dehydratase activity
AVCG678_07450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AVCG678_07475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG678_07500	COG0513	Belongs to the DEAD box helicase family
AVCG678_07505	COG1280	lysine exporter protein (LysE YggA)
AVCG678_07510	COG2945	thiolester hydrolase activity
AVCG678_07515	COG1104	cysteine desulfurase activity
AVCG678_07520	COG0719	Fe-S assembly protein
AVCG678_07525	COG0396	ATPase activity
AVCG678_07530	COG0719	Fe-S assembly protein
AVCG678_07540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AVCG678_07545	COG2151	metal-sulfur cluster biosynthetic enzyme
AVCG678_07560	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AVCG678_07575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AVCG678_07580	COG0343	queuine tRNA-ribosyltransferase activity
AVCG678_07590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AVCG678_07600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AVCG678_07605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG678_07610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVCG678_07615	COG2080	2 iron, 2 sulfur cluster binding
AVCG678_07645	COG2062	phosphohistidine phosphatase, SixA
AVCG678_07650	COG3106	COG3106 Predicted ATPase
AVCG678_07655	COG3768	UPF0283 membrane protein
AVCG678_07670	COG0436	Aminotransferase
AVCG678_07680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AVCG678_07685	COG0544	peptidyl-prolyl cis-trans isomerase activity
AVCG678_07715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AVCG678_07720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AVCG678_07735	COG0252	asparaginase activity
AVCG678_07745	COG0737	Belongs to the 5'-nucleotidase family
AVCG678_07755	COG0463	Glycosyl transferase, family 2
AVCG678_07760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AVCG678_07775	COG1116	anion transmembrane transporter activity
AVCG678_07780	COG3665	Urea carboxylase-associated protein
AVCG678_07790	COG4770	biotin carboxylase activity
AVCG678_07810	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AVCG678_07815	COG2153	protein acetylation
AVCG678_07820	COG1671	Belongs to the UPF0178 family
AVCG678_07830	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AVCG678_07835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG678_07845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG678_07850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVCG678_07855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AVCG678_07860	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVCG678_07865	COG0750	zinc metalloprotease
AVCG678_07875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AVCG678_07880	COG0233	cytoplasmic translational termination
AVCG678_07885	COG0528	UMP kinase activity
AVCG678_07890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AVCG678_07895	COG0052	Belongs to the universal ribosomal protein uS2 family
AVCG678_07920	COG0537	adenosine 5'-monophosphoramidase activity
AVCG678_07940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVCG678_07965	COG2267	carboxylic ester hydrolase activity
AVCG678_07985	COG0626	cystathionine gamma-synthase activity
AVCG678_07990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_07995	COG4597	amino acid ABC transporter
AVCG678_08000	COG0765	amino acid transport
AVCG678_08005	COG1126	abc transporter atp-binding protein
AVCG678_08010	COG0154	amidase activity
AVCG678_08015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AVCG678_08020	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AVCG678_08030	COG2313	pseudouridylate synthase activity
AVCG678_08035	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AVCG678_08040	COG0658	competence protein
AVCG678_08040	COG2333	competence protein COMEC
AVCG678_08045	COG0372	Belongs to the citrate synthase family
AVCG678_08055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AVCG678_08060	COG0134	indole-3-glycerol-phosphate synthase activity
AVCG678_08065	COG0315	cyclic pyranopterin monophosphate synthase activity
AVCG678_08070	COG0303	'Molybdopterin
AVCG678_08075	COG0671	phosphoesterase, PA-phosphatase related
AVCG678_08080	COG1492	cobalamin metabolic process
AVCG678_08090	COG4176	ABC-type proline glycine betaine transport system permease component
AVCG678_08095	COG0517	IMP dehydrogenase activity
AVCG678_08095	COG4175	Glycine betaine
AVCG678_08115	COG3698	Phosphodiester glycosidase
AVCG678_08140	COG0583	DNA-binding transcription factor activity
AVCG678_08175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG678_08195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVCG678_08205	COG0840	transmembrane signaling receptor activity
AVCG678_08215	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AVCG678_08225	COG1058	Belongs to the CinA family
AVCG678_08225	COG1546	Belongs to the CinA family
AVCG678_08230	COG2972	Histidine kinase
AVCG678_08230	COG0840	transmembrane signaling receptor activity
AVCG678_08240	COG0835	chemotaxis
AVCG678_08250	COG1760	l-serine dehydratase
AVCG678_08275	COG2239	Acts as a magnesium transporter
AVCG678_08305	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
AVCG678_08310	COG2099	Precorrin-6x reductase
AVCG678_08315	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVCG678_08330	COG2875	Belongs to the precorrin methyltransferase family
AVCG678_08355	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
AVCG678_08410	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AVCG678_08435	COG1862	Preprotein translocase
AVCG678_08450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVCG678_08455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AVCG678_08460	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVCG678_08465	COG0805	protein transport
AVCG678_08470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVCG678_08475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AVCG678_08480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVCG678_08485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AVCG678_08490	COG1472	Belongs to the glycosyl hydrolase 3 family
AVCG678_08500	COG0018	arginyl-trna synthetase
AVCG678_08505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AVCG678_08510	COG0316	Belongs to the HesB IscA family
AVCG678_08530	COG0525	valine-tRNA ligase activity
AVCG678_08545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AVCG678_08565	COG0584	glycerophosphoryl diester phosphodiesterase
AVCG678_08570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_08645	COG1403	HNH endonuclease
AVCG678_08750	COG0305	Participates in initiation and elongation during chromosome replication
AVCG678_08750	COG1372	Participates in initiation and elongation during chromosome replication
AVCG678_08830	COG0842	Transport permease protein
AVCG678_08835	COG1131	(ABC) transporter
AVCG678_08840	COG0745	RESPONSE REGULATOR receiver
AVCG678_08855	COG2226	methyltransferase
AVCG678_08860	COG3264	Mechanosensitive ion channel
AVCG678_08860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AVCG678_08880	COG4558	Periplasmic binding protein
AVCG678_08885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG678_08890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVCG678_08915	COG1201	RNA secondary structure unwinding
AVCG678_08950	COG0019	diaminopimelate decarboxylase activity
AVCG678_08960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVCG678_08975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AVCG678_08990	COG0483	inositol monophosphate 1-phosphatase activity
AVCG678_09040	COG0384	phenazine biosynthesis protein PhzF
AVCG678_09060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AVCG678_09105	COG0583	DNA-binding transcription factor activity
AVCG678_09175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AVCG678_09190	COG1522	sequence-specific DNA binding
AVCG678_09195	COG1794	racemase activity, acting on amino acids and derivatives
AVCG678_09200	COG1309	transcriptional regulator
AVCG678_09205	COG2814	Major facilitator Superfamily
AVCG678_09215	COG1733	regulation of RNA biosynthetic process
AVCG678_09225	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AVCG678_09235	COG0789	Transcriptional regulator
AVCG678_09240	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVCG678_09255	COG0656	L-ascorbic acid biosynthetic process
AVCG678_09270	COG0028	Belongs to the TPP enzyme family
AVCG678_09290	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AVCG678_09295	COG0560	Phosphoserine phosphatase
AVCG678_09295	COG3830	Belongs to the UPF0237 family
AVCG678_09310	COG0330	HflC and HflK could
AVCG678_09325	COG2259	Doxx family
AVCG678_09330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AVCG678_09365	COG0277	FAD linked oxidase domain protein
AVCG678_09370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AVCG678_09375	COG0581	inorganic phosphate transmembrane transporter activity
AVCG678_09380	COG0573	inorganic phosphate transmembrane transporter activity
AVCG678_09385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AVCG678_09405	COG4993	Dehydrogenase
AVCG678_09410	COG1335	isochorismatase
AVCG678_09415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AVCG678_09420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AVCG678_09430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AVCG678_09465	COG2264	protein methyltransferase activity
AVCG678_09470	COG1999	signal sequence binding
AVCG678_09475	COG0840	transmembrane signaling receptor activity
AVCG678_09480	COG0835	chemotaxis
AVCG678_09495	COG2176	DNA-directed DNA polymerase activity
AVCG678_09505	COG0840	transmembrane signaling receptor activity
AVCG678_09510	COG0456	acetyltransferase
AVCG678_09540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVCG678_09550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVCG678_09560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AVCG678_09570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVCG678_09575	COG0849	cell division
AVCG678_09580	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AVCG678_09585	COG1181	Belongs to the D-alanine--D-alanine ligase family
AVCG678_09590	COG0477	Major facilitator Superfamily
AVCG678_09595	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AVCG678_09600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AVCG678_09605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVCG678_09625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AVCG678_09635	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AVCG678_09650	COG0275	rRNA processing
AVCG678_09655	COG2001	Belongs to the MraZ family
AVCG678_09675	COG3023	N-Acetylmuramoyl-L-alanine amidase
AVCG678_09740	COG2226	methyltransferase
AVCG678_09745	COG0840	transmembrane signaling receptor activity
AVCG678_09750	COG0840	transmembrane signaling receptor activity
AVCG678_09765	COG2267	carboxylic ester hydrolase activity
AVCG678_09775	COG0028	Belongs to the TPP enzyme family
AVCG678_09790	COG0251	oxidation-reduction process
AVCG678_09805	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG678_09830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVCG678_09835	COG4149	molybdate abc transporter
AVCG678_09840	COG3842	ATPase activity
AVCG678_09855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVCG678_09860	COG2197	response regulator
AVCG678_09865	COG1396	sequence-specific DNA binding
AVCG678_09925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVCG678_09930	COG0697	spore germination
AVCG678_09940	COG2968	Membrane
AVCG678_09965	COG1278	Cold shock
AVCG678_10000	COG0432	Pfam Uncharacterised protein family UPF0047
AVCG678_10015	COG0583	DNA-binding transcription factor activity
AVCG678_10050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVCG678_10060	COG1268	BioY protein
AVCG678_10065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AVCG678_10075	COG0505	Belongs to the CarA family
AVCG678_10080	COG0534	Mate efflux family protein
AVCG678_10085	COG0583	DNA-binding transcription factor activity
AVCG678_10090	COG0667	Aldo Keto reductase
AVCG678_10095	COG2321	neutral zinc metallopeptidase
AVCG678_10110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AVCG678_10120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVCG678_10150	COG4641	Protein conserved in bacteria
AVCG678_10150	COG0438	transferase activity, transferring glycosyl groups
AVCG678_10155	COG1522	sequence-specific DNA binding
AVCG678_10160	COG0492	ferredoxin-NADP+ reductase activity
AVCG678_10165	COG0583	DNA-binding transcription factor activity
AVCG678_10170	COG0640	Transcriptional regulator
AVCG678_10175	COG1902	pentaerythritol trinitrate reductase activity
AVCG678_10195	COG0387	Pfam Sodium calcium exchanger
AVCG678_10205	COG0436	Aminotransferase
AVCG678_10225	COG1278	Cold shock
AVCG678_10230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG678_10240	COG1846	Transcriptional regulator
AVCG678_10245	COG0745	RESPONSE REGULATOR receiver
AVCG678_10250	COG2205	protein histidine kinase activity
AVCG678_10255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVCG678_10275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AVCG678_10290	COG0006	proline dipeptidase activity
AVCG678_10305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AVCG678_10320	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_10330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AVCG678_10345	COG0193	aminoacyl-tRNA hydrolase activity
AVCG678_10360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AVCG678_10365	COG0012	GTP binding
AVCG678_10385	COG0386	Belongs to the glutathione peroxidase family
AVCG678_10400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AVCG678_10405	COG2857	Cytochrome c1
AVCG678_10405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AVCG678_10435	COG3811	Belongs to the UPF0386 family
AVCG678_10440	COG1132	(ABC) transporter
AVCG678_10445	COG1132	(ABC) transporter
AVCG678_10450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AVCG678_10460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AVCG678_10470	COG0408	coproporphyrinogen oxidase activity
AVCG678_10485	COG0617	tRNA 3'-terminal CCA addition
AVCG678_10500	COG0714	Associated with various cellular activities
AVCG678_10525	COG0454	-acetyltransferase
AVCG678_10550	COG0435	Glutathione S-transferase
AVCG678_10565	COG0740	serine-type endopeptidase activity
AVCG678_10570	COG3135	benzoate transporter
AVCG678_10575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AVCG678_10630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVCG678_10630	COG0512	Glutamine amidotransferase of anthranilate synthase
AVCG678_10640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AVCG678_10645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AVCG678_10660	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AVCG678_10675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AVCG678_10685	COG2197	response regulator
AVCG678_10700	COG1435	thymidine kinase activity
AVCG678_10715	COG4175	Glycine betaine
AVCG678_10735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVCG678_10760	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVCG678_10770	COG4115	mRNA cleavage
AVCG678_10775	COG0366	Alpha amylase catalytic
AVCG678_10785	COG1160	GTP binding
AVCG678_10805	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AVCG678_10820	COG0024	Methionine aminopeptidase
AVCG678_10825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_10830	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AVCG678_10835	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_10845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG678_10855	COG0457	Tetratricopeptide repeat
AVCG678_10860	COG0583	DNA-binding transcription factor activity
AVCG678_10870	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_10875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG678_10885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG678_10890	COG0137	argininosuccinate synthase activity
AVCG678_10925	COG2351	hydroxyisourate hydrolase activity
AVCG678_10930	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AVCG678_10935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG678_10940	COG0174	glutamine synthetase
AVCG678_10950	COG3648	Uricase
AVCG678_10950	COG3195	allantoin biosynthetic process
AVCG678_10955	COG1064	alcohol dehydrogenase
AVCG678_10970	COG3706	GGDEF domain
AVCG678_10985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_10990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_10990	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVCG678_10995	COG5002	protein histidine kinase activity
AVCG678_10995	COG2205	protein histidine kinase activity
AVCG678_10995	COG0784	Response regulator, receiver
AVCG678_11005	COG0513	Belongs to the DEAD box helicase family
AVCG678_11020	COG1733	regulation of RNA biosynthetic process
AVCG678_11150	COG5005	Phage virion morphogenesis
AVCG678_11285	COG4133	protoheme IX ABC transporter activity
AVCG678_11315	COG0583	DNA-binding transcription factor activity
AVCG678_11330	COG2308	Evidence 4 Homologs of previously reported genes of
AVCG678_11360	COG2346	COG2346, Truncated hemoglobins
AVCG678_11380	COG0493	'glutamate synthase
AVCG678_11400	COG1309	transcriptional regulator
AVCG678_11425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG678_11430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG678_11435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG678_11460	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AVCG678_11465	COG0830	nickel cation binding
AVCG678_11470	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AVCG678_11475	COG5001	Diguanylate cyclase
AVCG678_11475	COG5002	protein histidine kinase activity
AVCG678_11495	COG0804	urea catabolic process
AVCG678_11500	COG1442	glycosyl transferase family 8
AVCG678_11505	COG3755	Protein conserved in bacteria
AVCG678_11510	COG0832	Belongs to the urease beta subunit family
AVCG678_11515	COG3813	Protein conserved in bacteria
AVCG678_11520	COG0831	urea catabolic process
AVCG678_11525	COG0829	nickel cation binding
AVCG678_11570	COG4251	negative regulation of phosphorylation
AVCG678_11580	COG2205	protein histidine kinase activity
AVCG678_11580	COG0784	Response regulator, receiver
AVCG678_11605	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AVCG678_11610	COG2894	cell division
AVCG678_11615	COG0850	regulation of cytokinetic process
AVCG678_11660	COG2814	Major facilitator Superfamily
AVCG678_11670	COG1218	3'(2'),5'-bisphosphate nucleotidase
AVCG678_11725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AVCG678_11735	COG0564	pseudouridine synthase activity
AVCG678_11740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_11740	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AVCG678_11745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AVCG678_11755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AVCG678_11770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVCG678_11780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AVCG678_11800	COG1116	anion transmembrane transporter activity
AVCG678_11810	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_11820	COG2249	NAD(P)H dehydrogenase (quinone) activity
AVCG678_11845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AVCG678_11880	COG1175	transmembrane transport
AVCG678_11905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AVCG678_11915	COG0482	sulfurtransferase activity
AVCG678_11925	COG4774	siderophore transport
AVCG678_11935	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AVCG678_11955	COG1120	ATPase activity
AVCG678_11965	COG4774	siderophore transport
AVCG678_11990	COG1294	oxidase, subunit
AVCG678_11995	COG1271	oxidase subunit
AVCG678_12000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AVCG678_12025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_12030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AVCG678_12035	COG0632	four-way junction helicase activity
AVCG678_12040	COG2002	toxin-antitoxin pair type II binding
AVCG678_12050	COG2255	four-way junction helicase activity
AVCG678_12055	COG1408	metallophosphoesterase
AVCG678_12060	COG0494	nUDIX hydrolase
AVCG678_12075	COG0824	Thioesterase
AVCG678_12095	COG0823	Involved in the tonB-independent uptake of proteins
AVCG678_12100	COG2885	chlorophyll binding
AVCG678_12110	COG0037	tRNA processing
AVCG678_12115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVCG678_12120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVCG678_12125	COG0217	transcriptional regulatory protein
AVCG678_12190	COG0840	transmembrane signaling receptor activity
AVCG678_12195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AVCG678_12200	COG1692	metallophosphoesterase
AVCG678_12205	COG0126	phosphoglycerate kinase activity
AVCG678_12210	COG3588	fructose-bisphosphate aldolase
AVCG678_12215	COG0384	phenazine biosynthesis protein PhzF
AVCG678_12250	COG0254	rRNA binding
AVCG678_12255	COG1132	(ABC) transporter
AVCG678_12275	COG0483	inositol monophosphate 1-phosphatase activity
AVCG678_12285	COG0352	thiamine-phosphate diphosphorylase activity
AVCG678_12295	COG0640	Transcriptional regulator
AVCG678_12310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AVCG678_12315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AVCG678_12320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AVCG678_12325	COG0457	Tetratricopeptide repeat
AVCG678_12330	COG0596	Alpha beta hydrolase
AVCG678_12335	COG0469	pyruvate kinase activity
AVCG678_12355	COG3750	Belongs to the UPF0335 family
AVCG678_12360	COG0583	DNA-binding transcription factor activity
AVCG678_12365	COG0679	Auxin Efflux Carrier
AVCG678_12385	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AVCG678_12385	COG0512	Glutamine amidotransferase of anthranilate synthase
AVCG678_12390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG678_12400	COG5310	Homospermidine synthase
AVCG678_12410	COG0737	Belongs to the 5'-nucleotidase family
AVCG678_12415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AVCG678_12425	COG0840	transmembrane signaling receptor activity
AVCG678_12435	COG0602	queuosine metabolic process
AVCG678_12440	COG0720	synthase
AVCG678_12445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AVCG678_12450	COG0330	HflC and HflK could
AVCG678_12460	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AVCG678_12460	COG0517	IMP dehydrogenase activity
AVCG678_12470	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AVCG678_12475	COG2951	lytic endotransglycosylase activity
AVCG678_12485	COG0840	transmembrane signaling receptor activity
AVCG678_12500	COG1487	ribonuclease activity
AVCG678_12510	COG0067	glutamate synthase
AVCG678_12510	COG0069	glutamate synthase activity
AVCG678_12510	COG0070	glutamate synthase
AVCG678_12520	COG0071	Belongs to the small heat shock protein (HSP20) family
AVCG678_12555	COG0668	transmembrane transport
AVCG678_12560	COG0662	Cupin 2, conserved barrel domain protein
AVCG678_12560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AVCG678_12570	COG2307	Protein conserved in bacteria
AVCG678_12570	COG2308	Evidence 4 Homologs of previously reported genes of
AVCG678_12590	COG0058	SHG alpha-glucan phosphorylase activity
AVCG678_12595	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVCG678_12600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AVCG678_12605	COG0297	glycogen (starch) synthase activity
AVCG678_12610	COG0033	Phosphoglucomutase
AVCG678_12650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVCG678_12655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_12665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG678_12665	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVCG678_12680	COG1733	regulation of RNA biosynthetic process
AVCG678_12685	COG3041	Addiction module toxin RelE StbE family
AVCG678_12690	COG3077	Addiction module antitoxin, RelB DinJ family
AVCG678_12720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AVCG678_12725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AVCG678_12730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG678_12735	COG1609	Transcriptional regulator
AVCG678_12740	COG1846	Transcriptional regulator
AVCG678_12750	COG0523	cobalamin synthesis protein
AVCG678_12765	COG3047	cAMP biosynthetic process
AVCG678_12790	COG0583	DNA-binding transcription factor activity
AVCG678_12820	COG0800	Aldolase
AVCG678_12825	COG2954	triphosphatase activity
AVCG678_12835	COG2378	regulation of single-species biofilm formation
AVCG678_12845	COG1054	Belongs to the UPF0176 family
AVCG678_12850	COG2202	Pas domain
AVCG678_12850	COG2199	diguanylate cyclase activity
AVCG678_12850	COG2200	EAL domain
AVCG678_12870	COG0673	inositol 2-dehydrogenase activity
AVCG678_12880	COG2115	Belongs to the xylose isomerase family
AVCG678_12885	COG1070	Carbohydrate kinase
AVCG678_12890	COG1609	Transcriptional regulator
AVCG678_12905	COG1309	transcriptional regulator
AVCG678_12910	COG1253	flavin adenine dinucleotide binding
AVCG678_12930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AVCG678_12945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AVCG678_12965	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AVCG678_12970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVCG678_12975	COG3273	potassium ion transport
AVCG678_12975	COG0471	metal ion transport
AVCG678_12990	COG2274	protein secretion by the type I secretion system
AVCG678_13025	COG4172	Belongs to the ABC transporter superfamily
AVCG678_13030	COG1473	amidohydrolase
AVCG678_13045	COG0601	transmembrane transport
AVCG678_13050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_13055	COG0842	Transport permease protein
AVCG678_13060	COG1129	ABC transporter
AVCG678_13060	COG0842	Transport permease protein
AVCG678_13065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG678_13070	COG3191	aminopeptidase activity
AVCG678_13075	COG3454	Phosphonate metabolism
AVCG678_13085	COG0444	Belongs to the ABC transporter superfamily
AVCG678_13090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_13095	COG0601	transmembrane transport
AVCG678_13100	COG0747	negative chemotaxis
AVCG678_13110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG678_13115	COG1802	Transcriptional regulator
AVCG678_13120	COG1904	glucuronate isomerase
AVCG678_13125	COG1917	Cupin 2, conserved barrel domain protein
AVCG678_13135	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_13140	COG0246	Mannitol dehydrogenase
AVCG678_13145	COG1312	Catalyzes the dehydration of D-mannonate
AVCG678_13150	COG2721	sulfolactate sulfo-lyase activity
AVCG678_13160	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AVCG678_13175	COG4213	ABC transporter substrate-binding protein
AVCG678_13185	COG4214	carbohydrate transport
AVCG678_13195	COG0129	dihydroxy-acid dehydratase activity
AVCG678_13210	COG3734	2-keto-3-deoxy-galactonokinase
AVCG678_13215	COG0800	Aldolase
AVCG678_13220	COG2832	Protein of unknown function (DUF454)
AVCG678_13225	COG0697	spore germination
AVCG678_13230	COG2186	Transcriptional regulator
AVCG678_13235	COG2807	transmembrane transport
AVCG678_13245	COG4953	penicillin-binding protein 1C
AVCG678_13250	COG0840	transmembrane signaling receptor activity
AVCG678_13250	COG2972	Histidine kinase
AVCG678_13255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG678_13260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AVCG678_13265	COG0438	transferase activity, transferring glycosyl groups
AVCG678_13275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_13280	COG0601	transmembrane transport
AVCG678_13285	COG0747	negative chemotaxis
AVCG678_13325	COG1132	(ABC) transporter
AVCG678_13335	COG0419	ATPase involved in DNA repair
AVCG678_13340	COG0840	transmembrane signaling receptor activity
AVCG678_13380	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AVCG678_13390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG678_13395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG678_13405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AVCG678_13420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AVCG678_13430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AVCG678_13460	COG0438	transferase activity, transferring glycosyl groups
AVCG678_13485	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVCG678_13505	COG1793	dna ligase
AVCG678_13525	COG0783	Belongs to the Dps family
AVCG678_13535	COG0784	Response regulator, receiver
AVCG678_13575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG678_13590	COG0848	biopolymer transport protein
AVCG678_13600	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVCG678_13615	COG0010	Belongs to the arginase family
AVCG678_13635	COG1940	carbohydrate kinase activity
AVCG678_13655	COG1072	(Pantothenic acid kinase))
AVCG678_13660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_13665	COG0765	amino acid transport
AVCG678_13670	COG0765	amino acid transport
AVCG678_13675	COG4598	ABC transporter
AVCG678_13690	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_13695	COG1228	amidohydrolase
AVCG678_13700	COG2986	histidine ammonia-lyase
AVCG678_13710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AVCG678_13730	COG1289	transmembrane transporter activity
AVCG678_13750	COG0583	DNA-binding transcription factor activity
AVCG678_13755	COG0346	lactoylglutathione lyase activity
AVCG678_13760	COG0400	carboxylic ester hydrolase activity
AVCG678_13780	COG3307	-O-antigen
AVCG678_13785	COG1596	polysaccharide export
AVCG678_13790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AVCG678_13800	COG1215	transferase activity, transferring glycosyl groups
AVCG678_13805	COG2327	Polysaccharide pyruvyl transferase
AVCG678_13810	COG0463	Glycosyl transferase, family 2
AVCG678_13815	COG2244	polysaccharide biosynthetic process
AVCG678_13825	COG2273	Hydrolase Family 16
AVCG678_13830	COG0438	transferase activity, transferring glycosyl groups
AVCG678_13835	COG1215	transferase activity, transferring glycosyl groups
AVCG678_13840	COG1215	transferase activity, transferring glycosyl groups
AVCG678_13845	COG1215	transferase activity, transferring glycosyl groups
AVCG678_13850	COG3206	protein involved in exopolysaccharide biosynthesis
AVCG678_13850	COG0489	protein tyrosine kinase activity
AVCG678_13905	COG0542	response to heat
AVCG678_13915	COG2890	protein-(glutamine-N5) methyltransferase activity
AVCG678_13920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AVCG678_13930	COG0527	aspartate kinase activity
AVCG678_13950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AVCG678_13965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVCG678_13970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVCG678_13980	COG2226	methyltransferase
AVCG678_13995	COG0494	nUDIX hydrolase
AVCG678_14005	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AVCG678_14010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AVCG678_14015	COG0653	protein targeting
AVCG678_14030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVCG678_14080	COG0667	Aldo Keto reductase
AVCG678_14125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AVCG678_14135	COG0300	oxidoreductase activity
AVCG678_14150	COG2086	electron transfer activity
AVCG678_14160	COG2972	Histidine kinase
AVCG678_14160	COG0840	transmembrane signaling receptor activity
AVCG678_14165	COG1250	3-hydroxyacyl-CoA dehydrogenase
AVCG678_14175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AVCG678_14180	COG0165	Argininosuccinate lyase
AVCG678_14190	COG0019	diaminopimelate decarboxylase activity
AVCG678_14205	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AVCG678_14215	COG2884	Cell division ATP-binding protein ftsE
AVCG678_14235	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AVCG678_14245	COG0287	Prephenate dehydrogenase
AVCG678_14250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AVCG678_14255	COG2226	methyltransferase
AVCG678_14260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AVCG678_14285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AVCG678_14290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AVCG678_14320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AVCG678_14325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AVCG678_14335	COG4974	Belongs to the 'phage' integrase family
AVCG678_14340	COG0825	malonyl-CoA metabolic process
AVCG678_14345	COG3034	peptidoglycan biosynthetic process
AVCG678_14355	COG0523	cobalamin synthesis protein
AVCG678_14360	COG1686	Belongs to the peptidase S11 family
AVCG678_14365	COG1473	amidohydrolase
AVCG678_14375	COG0628	permease
AVCG678_14385	COG2771	luxR family
AVCG678_14390	COG1766	The M ring may be actively involved in energy transduction
AVCG678_14400	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AVCG678_14405	COG0745	RESPONSE REGULATOR receiver
AVCG678_14410	COG2201	protein-glutamate methylesterase activity
AVCG678_14415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG678_14420	COG0835	chemotaxis
AVCG678_14425	COG0643	Histidine kinase
AVCG678_14425	COG2198	Histidine kinase
AVCG678_14430	COG0745	RESPONSE REGULATOR receiver
AVCG678_14440	COG0840	transmembrane signaling receptor activity
AVCG678_14445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AVCG678_14455	COG0156	8-amino-7-oxononanoate synthase activity
AVCG678_14465	COG0729	surface antigen
AVCG678_14480	COG0835	chemotaxis
AVCG678_14485	COG2223	nitrite transmembrane transporter activity
AVCG678_14495	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AVCG678_14500	COG3383	formate dehydrogenase (NAD+) activity
AVCG678_14515	COG0583	DNA-binding transcription factor activity
AVCG678_14520	COG0640	Transcriptional regulator
AVCG678_14525	COG0039	L-malate dehydrogenase activity
AVCG678_14530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AVCG678_14535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AVCG678_14540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AVCG678_14545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AVCG678_14550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AVCG678_14565	COG0840	transmembrane signaling receptor activity
AVCG678_14565	COG2972	Histidine kinase
AVCG678_14575	COG4974	Belongs to the 'phage' integrase family
AVCG678_14600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AVCG678_14610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AVCG678_14620	COG0045	succinate-CoA ligase (ADP-forming) activity
AVCG678_14625	COG0039	L-malate dehydrogenase activity
AVCG678_14630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AVCG678_14680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AVCG678_14685	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AVCG678_14690	COG0181	hydroxymethylbilane synthase activity
AVCG678_14730	COG1872	DUF167
AVCG678_14735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AVCG678_14745	COG1217	gtp-binding protein TYPA
AVCG678_14755	COG0339	signal peptide processing
AVCG678_14765	COG0137	argininosuccinate synthase activity
AVCG678_14780	COG1280	lysine exporter protein (LysE YggA)
AVCG678_14790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AVCG678_14805	COG2154	pterin-4-alpha-carbinolamine dehydratase
AVCG678_14810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AVCG678_14820	COG1136	(ABC) transporter
AVCG678_14825	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AVCG678_14830	COG0670	Belongs to the BI1 family
AVCG678_14850	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AVCG678_14855	COG4133	protoheme IX ABC transporter activity
AVCG678_14860	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVCG678_14865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AVCG678_14885	COG2917	probably involved in intracellular septation
AVCG678_14890	COG0552	protein localization to endoplasmic reticulum
AVCG678_14895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AVCG678_14900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AVCG678_14915	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AVCG678_14920	COG0287	Prephenate dehydrogenase
AVCG678_14920	COG1605	Chorismate mutase
AVCG678_14925	COG0228	four-way junction DNA binding
AVCG678_14930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AVCG678_14935	COG0336	Belongs to the RNA methyltransferase TrmD family
AVCG678_14945	COG0335	large ribosomal subunit rRNA binding
AVCG678_14960	COG2372	response to copper ion
AVCG678_14965	COG2372	response to copper ion
AVCG678_14965	COG1276	copper resistance
AVCG678_14975	COG0765	amino acid transport
AVCG678_14995	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AVCG678_15010	COG0745	RESPONSE REGULATOR receiver
AVCG678_15030	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AVCG678_15035	COG1674	ftsk spoiiie
AVCG678_15040	COG0004	ammonium transporteR
AVCG678_15045	COG0347	Belongs to the P(II) protein family
AVCG678_15050	COG1946	Acyl-CoA thioesterase
AVCG678_15055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG678_15060	COG2835	tetraacyldisaccharide 4'-kinase activity
AVCG678_15065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AVCG678_15070	COG3118	belongs to the thioredoxin family
AVCG678_15090	COG2017	converts alpha-aldose to the beta-anomer
AVCG678_15105	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AVCG678_15110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AVCG678_15125	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AVCG678_15135	COG0488	(ABC) transporter
AVCG678_15165	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AVCG678_15195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AVCG678_15200	COG0799	negative regulation of ribosome biogenesis
AVCG678_15205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AVCG678_15210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AVCG678_15215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AVCG678_15220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AVCG678_15240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AVCG678_15245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AVCG678_15265	COG0138	bifunctional purine biosynthesis protein purh
AVCG678_15275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVCG678_15275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVCG678_15280	COG0501	Belongs to the peptidase M48B family
AVCG678_15300	COG0793	Belongs to the peptidase S41A family
AVCG678_15310	COG0494	nUDIX hydrolase
AVCG678_15315	COG1192	Involved in chromosome partitioning
AVCG678_15340	COG2201	protein-glutamate methylesterase activity
AVCG678_15345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG678_15350	COG0835	chemotaxis
AVCG678_15355	COG0840	transmembrane signaling receptor activity
AVCG678_15360	COG0840	transmembrane signaling receptor activity
AVCG678_15360	COG3290	protein histidine kinase activity
AVCG678_15365	COG0840	transmembrane signaling receptor activity
AVCG678_15370	COG0835	chemotaxis
AVCG678_15375	COG0643	Histidine kinase
AVCG678_15375	COG2198	Histidine kinase
AVCG678_15380	COG0745	RESPONSE REGULATOR receiver
AVCG678_15405	COG1522	sequence-specific DNA binding
AVCG678_15420	COG4221	oxidoreductase activity
AVCG678_15425	COG0156	8-amino-7-oxononanoate synthase activity
AVCG678_15435	COG0738	Major facilitator superfamily
AVCG678_15440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AVCG678_15445	COG2885	chlorophyll binding
AVCG678_15455	COG0142	geranyltranstransferase activity
AVCG678_15460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AVCG678_15470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AVCG678_15475	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AVCG678_15480	COG0183	Belongs to the thiolase family
AVCG678_15510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVCG678_15530	COG2301	Belongs to the HpcH HpaI aldolase family
AVCG678_15540	COG0066	3-isopropylmalate dehydratase activity
AVCG678_15545	COG0473	3-isopropylmalate dehydrogenase activity
AVCG678_15550	COG0671	phosphoesterase, PA-phosphatase related
AVCG678_15560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AVCG678_15570	COG2010	Cytochrome c
AVCG678_15575	COG0288	reversible hydration of carbon dioxide
AVCG678_15580	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AVCG678_15585	COG2902	Dehydrogenase
AVCG678_15595	COG3459	Glycosyltransferase 36 associated
AVCG678_15600	COG1473	amidohydrolase
AVCG678_15615	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AVCG678_15625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AVCG678_15635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AVCG678_15640	COG0495	leucyl-tRNA aminoacylation
AVCG678_15665	COG0357	Ribosomal RNA small subunit methyltransferase G
AVCG678_15670	COG0445	tRNA wobble uridine modification
AVCG678_15675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AVCG678_15680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AVCG678_15685	COG1981	membrane
AVCG678_15690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AVCG678_15695	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AVCG678_15700	COG0424	maF-like protein
AVCG678_15705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVCG678_15710	COG0237	dephospho-CoA kinase activity
AVCG678_15720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AVCG678_15735	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AVCG678_15775	COG0135	phosphoribosylanthranilate isomerase activity
AVCG678_15780	COG0133	tryptophan synthase activity
AVCG678_15785	COG0159	tryptophan synthase activity
AVCG678_15790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AVCG678_15795	COG0285	dihydrofolate synthase activity
AVCG678_15830	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AVCG678_15835	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AVCG678_15840	COG0131	Imidazoleglycerol-phosphate dehydratase
AVCG678_15845	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AVCG678_15850	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AVCG678_15855	COG0107	imidazoleglycerol-phosphate synthase activity
AVCG678_15860	COG0140	phosphoribosyl-ATP diphosphatase activity
AVCG678_15865	COG1072	(Pantothenic acid kinase))
AVCG678_15880	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AVCG678_15885	COG0745	RESPONSE REGULATOR receiver
AVCG678_15890	COG0642	Histidine kinase
AVCG678_15900	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AVCG678_15900	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVCG678_15905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AVCG678_15910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AVCG678_15915	COG2205	protein histidine kinase activity
AVCG678_15920	COG3178	'Phosphotransferase
AVCG678_15925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AVCG678_15930	COG2887	Belongs to the helicase family. UvrD subfamily
AVCG678_15935	COG1074	ATP-dependent DNA helicase activity
AVCG678_15940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AVCG678_15955	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AVCG678_15965	COG1643	Atp-dependent helicase
AVCG678_15970	COG2423	ornithine cyclodeaminase activity
AVCG678_16015	COG2814	Major facilitator Superfamily
AVCG678_16020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_16035	COG0673	inositol 2-dehydrogenase activity
AVCG678_16045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG678_16050	COG3962	Belongs to the TPP enzyme family
AVCG678_16065	COG3718	enzyme involved in inositol metabolism
AVCG678_16090	COG4221	oxidoreductase activity
AVCG678_16095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG678_16110	COG1595	DNA-templated transcription, initiation
AVCG678_16115	COG3806	Anti-sigma factor
AVCG678_16135	COG3842	ATPase activity
AVCG678_16140	COG3842	ATPase activity
AVCG678_16150	COG0395	ABC-type sugar transport system, permease component
AVCG678_16165	COG3474	cytochrome
AVCG678_16170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AVCG678_16175	COG0077	Prephenate dehydratase
AVCG678_16175	COG1605	Chorismate mutase
AVCG678_16185	COG2816	NAD+ diphosphatase activity
AVCG678_16200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AVCG678_16205	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AVCG678_16215	COG3422	double-strand break repair
AVCG678_16230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AVCG678_16235	COG0481	GTPase activity
AVCG678_16250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AVCG678_16255	COG1607	acyl-coa hydrolase
AVCG678_16280	COG1393	Belongs to the ArsC family
AVCG678_16285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVCG678_16290	COG2309	aminopeptidase activity
AVCG678_16305	COG1278	Cold shock
AVCG678_16310	COG1570	exodeoxyribonuclease VII activity
AVCG678_16350	COG0667	Aldo Keto reductase
AVCG678_16365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AVCG678_16370	COG2951	lytic endotransglycosylase activity
AVCG678_16400	COG2814	Major facilitator Superfamily
AVCG678_16410	COG0779	Required for maturation of 30S ribosomal subunits
AVCG678_16415	COG0195	Participates in both transcription termination and antitermination
AVCG678_16415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AVCG678_16425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AVCG678_16430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AVCG678_16435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AVCG678_16440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AVCG678_16445	COG1185	polyribonucleotide nucleotidyltransferase activity
AVCG678_16450	COG2813	Specifically methylates the guanine in position
AVCG678_16455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AVCG678_16465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AVCG678_16475	COG2860	membrane
AVCG678_16485	COG0477	Major facilitator Superfamily
AVCG678_16500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AVCG678_16505	COG0539	negative regulation of cytoplasmic translation
AVCG678_16525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AVCG678_16540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AVCG678_16545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AVCG678_16550	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AVCG678_16560	COG0072	phenylalanine-tRNA ligase activity
AVCG678_16560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AVCG678_16605	COG4964	Belongs to the GSP D family
AVCG678_16645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AVCG678_16650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AVCG678_16655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVCG678_16665	COG1280	lysine exporter protein (LysE YggA)
AVCG678_16670	COG0588	phosphoglycerate mutase activity
AVCG678_16675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AVCG678_16680	COG1132	(ABC) transporter
AVCG678_16685	COG0837	glucose binding
AVCG678_16690	COG1803	Methylglyoxal synthase
AVCG678_16695	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AVCG678_16700	COG4166	transmembrane transport
AVCG678_16705	COG4174	ABC transporter (Permease)
AVCG678_16710	COG4239	(ABC) transporter, permease
AVCG678_16715	COG4172	Belongs to the ABC transporter superfamily
AVCG678_16730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AVCG678_16760	COG1744	ABC transporter substrate-binding protein PnrA-like
AVCG678_16765	COG3845	ABC transporter
AVCG678_16770	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_16775	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_16790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AVCG678_16795	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AVCG678_16800	COG2188	Transcriptional regulator
AVCG678_16805	COG3624	Phosphonate C-P lyase system protein PhnG
AVCG678_16810	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AVCG678_16815	COG3626	phosphonate metabolism
AVCG678_16820	COG3627	carbon phosphorus lyase activity
AVCG678_16825	COG4107	phosphonate C-P lyase system protein PhnK
AVCG678_16830	COG4778	phosphonate C-P lyase system protein PhnL
AVCG678_16840	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AVCG678_16845	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AVCG678_16855	COG3639	organic phosphonate transmembrane transporter activity
AVCG678_16860	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVCG678_16865	COG3454	Phosphonate metabolism
AVCG678_16870	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AVCG678_16880	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AVCG678_16885	COG2353	YceI-like domain
AVCG678_16890	COG2353	YceI-like domain
AVCG678_16900	COG0791	NLP P60 protein
AVCG678_16910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVCG678_16910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AVCG678_16920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG678_16925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AVCG678_16940	COG0443	Heat shock 70 kDa protein
AVCG678_16950	COG0484	heat shock protein binding
AVCG678_16955	COG2900	Belongs to the SlyX family
AVCG678_16960	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AVCG678_16975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG678_16985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG678_16990	COG3300	MHYT domain
AVCG678_16990	COG5001	Diguanylate cyclase
AVCG678_16995	COG3002	Belongs to the UPF0753 family
AVCG678_17000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVCG678_17025	COG0519	Catalyzes the synthesis of GMP from XMP
AVCG678_17025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AVCG678_17040	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AVCG678_17065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AVCG678_17065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AVCG678_17070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AVCG678_17080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AVCG678_17090	COG1968	undecaprenyl-diphosphatase activity
AVCG678_17110	COG0284	orotidine-5'-phosphate decarboxylase activity
AVCG678_17120	COG3963	phosphatidate phosphatase activity
AVCG678_17130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AVCG678_17135	COG0792	nuclease activity
AVCG678_17145	COG1175	transmembrane transport
AVCG678_17150	COG0395	ABC-type sugar transport system, permease component
AVCG678_17155	COG3842	ATPase activity
AVCG678_17165	COG0189	ligase activity
AVCG678_17170	COG0606	chelatase, subunit chli
AVCG678_17185	COG1280	lysine exporter protein (LysE YggA)
AVCG678_17190	COG0756	dUTP diphosphatase activity
AVCG678_17195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AVCG678_17200	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AVCG678_17205	COG1877	trehalose-phosphatase activity
AVCG678_17225	COG1741	Belongs to the pirin family
AVCG678_17235	COG0583	DNA-binding transcription factor activity
AVCG678_17250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AVCG678_17255	COG3920	Histidine kinase
AVCG678_17260	COG0784	Response regulator, receiver
AVCG678_17265	COG2205	protein histidine kinase activity
AVCG678_17265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_17265	COG0784	Response regulator, receiver
AVCG678_17265	COG2198	Histidine kinase
AVCG678_17270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AVCG678_17275	COG2226	methyltransferase
AVCG678_17280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AVCG678_17285	COG0268	Binds directly to 16S ribosomal RNA
AVCG678_17290	COG1192	Involved in chromosome partitioning
AVCG678_17295	COG1475	DNA binding
AVCG678_17300	COG1414	Transcriptional regulator
AVCG678_17305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AVCG678_17310	COG0392	lysyltransferase activity
AVCG678_17320	COG3257	ureidoglycine aminohydrolase activity
AVCG678_17340	COG1522	sequence-specific DNA binding
AVCG678_17365	COG2040	homocysteine
AVCG678_17370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG678_17380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVCG678_17385	COG1473	amidohydrolase
AVCG678_17395	COG0297	glycogen (starch) synthase activity
AVCG678_17420	COG1063	alcohol dehydrogenase
AVCG678_17425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG678_17430	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_17435	COG3265	gluconokinase activity
AVCG678_17440	COG2084	Dehydrogenase
AVCG678_17450	COG1609	Transcriptional regulator
AVCG678_17465	COG1129	ABC transporter
AVCG678_17480	COG1879	ABC-type sugar transport system periplasmic component
AVCG678_17485	COG1129	ABC transporter
AVCG678_17490	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_17495	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_17500	COG2186	Transcriptional regulator
AVCG678_17505	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_17510	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_17520	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG678_17530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG678_17535	COG1116	anion transmembrane transporter activity
AVCG678_17555	COG0778	Nitroreductase
AVCG678_17565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AVCG678_17570	COG0659	secondary active sulfate transmembrane transporter activity
AVCG678_17575	COG0589	response to stress
AVCG678_17635	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVCG678_17650	COG1802	Transcriptional regulator
AVCG678_17660	COG2723	6-phospho-beta-galactosidase activity
AVCG678_17665	COG0601	transmembrane transport
AVCG678_17675	COG3964	amidohydrolase
AVCG678_17690	COG1921	L-seryl-tRNASec selenium transferase activity
AVCG678_17695	COG2203	Gaf domain
AVCG678_17695	COG3706	GGDEF domain
AVCG678_17695	COG4251	negative regulation of phosphorylation
AVCG678_17695	COG5001	Diguanylate cyclase
AVCG678_17715	COG2080	2 iron, 2 sulfur cluster binding
AVCG678_17720	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AVCG678_17725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG678_17750	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_17760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AVCG678_17765	COG1486	melibiose metabolic process
AVCG678_17770	COG4172	Belongs to the ABC transporter superfamily
AVCG678_17775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_17780	COG0601	transmembrane transport
AVCG678_17785	COG0747	negative chemotaxis
AVCG678_17790	COG1486	melibiose metabolic process
AVCG678_17795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AVCG678_17795	COG2207	Transcriptional regulator
AVCG678_17825	COG1063	alcohol dehydrogenase
AVCG678_17830	COG4948	Mandelate Racemase Muconate Lactonizing
AVCG678_17850	COG4214	carbohydrate transport
AVCG678_17855	COG1129	ABC transporter
AVCG678_17870	COG1175	transmembrane transport
AVCG678_17875	COG0395	ABC-type sugar transport system, permease component
AVCG678_17895	COG1609	Transcriptional regulator
AVCG678_17910	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_17925	COG0840	transmembrane signaling receptor activity
AVCG678_17925	COG2972	Histidine kinase
AVCG678_17950	COG0667	Aldo Keto reductase
AVCG678_17965	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_17975	COG4213	ABC transporter substrate-binding protein
AVCG678_17990	COG1129	ABC transporter
AVCG678_17995	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_18000	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_18005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_18020	COG0765	amino acid transport
AVCG678_18025	COG1126	abc transporter atp-binding protein
AVCG678_18030	COG2079	MmgE PrpD family protein
AVCG678_18035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_18045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_18055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_18065	COG0747	negative chemotaxis
AVCG678_18080	COG2197	response regulator
AVCG678_18085	COG5002	protein histidine kinase activity
AVCG678_18085	COG3850	Histidine kinase
AVCG678_18090	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AVCG678_18100	COG2731	YhcH YjgK YiaL family protein
AVCG678_18105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_18110	COG2271	Major facilitator Superfamily
AVCG678_18115	COG1609	Transcriptional regulator
AVCG678_18120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_18125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_18130	COG1473	amidohydrolase
AVCG678_18140	COG1126	abc transporter atp-binding protein
AVCG678_18145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_18155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_18175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG678_18195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG678_18205	COG1960	acyl-CoA dehydrogenase activity
AVCG678_18215	COG1309	transcriptional regulator
AVCG678_18245	COG2207	Transcriptional regulator
AVCG678_18255	COG0235	Class ii aldolase
AVCG678_18285	COG4221	oxidoreductase activity
AVCG678_18315	COG1595	DNA-templated transcription, initiation
AVCG678_18325	COG2824	Alkylphosphonate utilization operon protein PhnA
AVCG678_18350	COG3833	ABC-type maltose transport systems, permease component
AVCG678_18355	COG3842	ATPase activity
AVCG678_18360	COG0584	glycerophosphoryl diester phosphodiesterase
AVCG678_18400	COG1320	monovalent cation:proton antiporter activity
AVCG678_18405	COG2212	antiporter activity
AVCG678_18410	COG1863	multisubunit Na H antiporter MnhE subunit
AVCG678_18415	COG0651	ATP synthesis coupled electron transport
AVCG678_18420	COG1006	Multisubunit Na H antiporter MnhC subunit
AVCG678_18425	COG2111	Na H antiporter
AVCG678_18425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AVCG678_18445	COG3845	ABC transporter
AVCG678_18450	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVCG678_18455	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_18460	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_18465	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_18480	COG2072	flavoprotein involved in K transport
AVCG678_18485	COG1177	transmembrane transport
AVCG678_18490	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_18495	COG3842	ATPase activity
AVCG678_18500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AVCG678_18505	COG0583	DNA-binding transcription factor activity
AVCG678_18530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_18535	COG0444	Belongs to the ABC transporter superfamily
AVCG678_18540	COG4608	Belongs to the ABC transporter superfamily
AVCG678_18565	COG0601	transmembrane transport
AVCG678_18570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_18590	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_18595	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_18600	COG1846	Transcriptional regulator
AVCG678_18630	COG0625	glutathione transferase activity
AVCG678_18650	COG2133	pyrroloquinoline quinone binding
AVCG678_18660	COG0438	transferase activity, transferring glycosyl groups
AVCG678_18675	COG0753	catalase activity
AVCG678_18680	COG0306	phosphate transporter
AVCG678_18685	COG3842	ATPase activity
AVCG678_18690	COG1175	transmembrane transport
AVCG678_18695	COG0395	ABC-type sugar transport system, permease component
AVCG678_18720	COG3684	Belongs to the aldolase LacD family
AVCG678_18725	COG2390	Transcriptional regulator
AVCG678_18745	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_18755	COG0626	cystathionine gamma-synthase activity
AVCG678_18760	COG1725	Transcriptional regulator
AVCG678_18765	COG0747	negative chemotaxis
AVCG678_18770	COG0601	transmembrane transport
AVCG678_18775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_18780	COG0444	Belongs to the ABC transporter superfamily
AVCG678_18785	COG4608	Belongs to the ABC transporter superfamily
AVCG678_18790	COG0006	proline dipeptidase activity
AVCG678_18800	COG0747	negative chemotaxis
AVCG678_18810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_18815	COG0405	Gamma-glutamyltransferase
AVCG678_18825	COG0754	glutathionylspermidine amidase activity
AVCG678_18835	COG3766	membrane
AVCG678_18845	COG3789	protein conserved in bacteria
AVCG678_18860	COG0318	PFAM AMP-dependent synthetase and ligase
AVCG678_18870	COG1802	Transcriptional regulator
AVCG678_18880	COG0601	transmembrane transport
AVCG678_18885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_18910	COG0747	negative chemotaxis
AVCG678_18920	COG2205	protein histidine kinase activity
AVCG678_18925	COG2197	response regulator
AVCG678_18930	COG4585	Histidine kinase
AVCG678_18945	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AVCG678_18950	COG4208	sulfate ABC transporter
AVCG678_18955	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AVCG678_18960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AVCG678_18965	COG1609	Transcriptional regulator
AVCG678_18970	COG0673	inositol 2-dehydrogenase activity
AVCG678_18980	COG1653	transport
AVCG678_18985	COG1175	transmembrane transport
AVCG678_18990	COG0395	ABC-type sugar transport system, permease component
AVCG678_18995	COG3842	ATPase activity
AVCG678_19005	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AVCG678_19020	COG0583	DNA-binding transcription factor activity
AVCG678_19025	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_19030	COG3250	beta-galactosidase activity
AVCG678_19035	COG1940	carbohydrate kinase activity
AVCG678_19040	COG2116	formate transmembrane transporter activity
AVCG678_19045	COG0402	S-adenosylhomocysteine deaminase activity
AVCG678_19055	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_19060	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVCG678_19065	COG3845	ABC transporter
AVCG678_19090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVCG678_19095	COG0583	DNA-binding transcription factor activity
AVCG678_19110	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AVCG678_19125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AVCG678_19130	COG2080	2 iron, 2 sulfur cluster binding
AVCG678_19135	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_19150	COG2186	Transcriptional regulator
AVCG678_19155	COG1304	FMN binding
AVCG678_19165	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVCG678_19210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AVCG678_19215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AVCG678_19220	COG1126	abc transporter atp-binding protein
AVCG678_19225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_19230	COG0765	amino acid transport
AVCG678_19235	COG0765	amino acid transport
AVCG678_19245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVCG678_19255	COG1764	response to oxidative stress
AVCG678_19270	COG1116	anion transmembrane transporter activity
AVCG678_19275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG678_19280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG678_19285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG678_19290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_19295	COG1959	2 iron, 2 sulfur cluster binding
AVCG678_19320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AVCG678_19355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG678_19375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG678_19385	COG1116	anion transmembrane transporter activity
AVCG678_19395	COG4191	Histidine kinase
AVCG678_19400	COG4566	intracellular signal transduction
AVCG678_19410	COG3842	ATPase activity
AVCG678_19415	COG0395	ABC-type sugar transport system, permease component
AVCG678_19420	COG1175	transmembrane transport
AVCG678_19455	COG1940	carbohydrate kinase activity
AVCG678_19460	COG0747	negative chemotaxis
AVCG678_19465	COG0601	transmembrane transport
AVCG678_19470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_19480	COG4608	Belongs to the ABC transporter superfamily
AVCG678_19485	COG0745	RESPONSE REGULATOR receiver
AVCG678_19490	COG2205	protein histidine kinase activity
AVCG678_19500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVCG678_19510	COG2076	Multidrug Resistance protein
AVCG678_19530	COG2076	Multidrug Resistance protein
AVCG678_19545	COG1215	transferase activity, transferring glycosyl groups
AVCG678_19560	COG3920	Histidine kinase
AVCG678_19560	COG2202	Pas domain
AVCG678_19570	COG0784	Response regulator, receiver
AVCG678_19580	COG1162	GTPase activity
AVCG678_19585	COG4191	Histidine kinase
AVCG678_19585	COG0784	Response regulator, receiver
AVCG678_19590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG678_19605	COG1126	abc transporter atp-binding protein
AVCG678_19610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_19625	COG2972	Histidine kinase
AVCG678_19625	COG0840	transmembrane signaling receptor activity
AVCG678_19630	COG0835	chemotaxis
AVCG678_19640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AVCG678_19655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG678_19665	COG0789	Transcriptional regulator
AVCG678_19670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AVCG678_19675	COG0366	Alpha amylase catalytic
AVCG678_19680	COG0366	Alpha amylase catalytic
AVCG678_19685	COG1640	4-alpha-glucanotransferase
AVCG678_19690	COG1278	Cold shock
AVCG678_19695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AVCG678_19705	COG0673	inositol 2-dehydrogenase activity
AVCG678_19715	COG1802	Transcriptional regulator
AVCG678_19720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_19730	COG0673	inositol 2-dehydrogenase activity
AVCG678_19740	COG1175	transmembrane transport
AVCG678_19745	COG0395	ABC-type sugar transport system, permease component
AVCG678_19755	COG0673	inositol 2-dehydrogenase activity
AVCG678_19765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AVCG678_19775	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_19785	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AVCG678_19790	COG3920	Histidine kinase
AVCG678_19805	COG3685	Protein conserved in bacteria
AVCG678_19835	COG5001	Diguanylate cyclase
AVCG678_19855	COG1132	(ABC) transporter
AVCG678_19860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AVCG678_19860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG678_19875	COG3842	ATPase activity
AVCG678_19880	COG3833	ABC-type maltose transport systems, permease component
AVCG678_19895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AVCG678_19925	COG0604	alcohol dehydrogenase
AVCG678_19925	COG3321	synthase
AVCG678_19935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AVCG678_19935	COG2070	2-Nitropropane dioxygenase
AVCG678_19945	COG1960	acyl-CoA dehydrogenase activity
AVCG678_19955	COG4608	Belongs to the ABC transporter superfamily
AVCG678_19970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_19975	COG0747	negative chemotaxis
AVCG678_19995	COG0583	DNA-binding transcription factor activity
AVCG678_20000	COG0747	negative chemotaxis
AVCG678_20010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_20025	COG0154	amidase activity
AVCG678_20040	COG1335	isochorismatase
AVCG678_20045	COG3845	ABC transporter
AVCG678_20060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AVCG678_20065	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_20085	COG4172	Belongs to the ABC transporter superfamily
AVCG678_20090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_20095	COG0601	transmembrane transport
AVCG678_20125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_20135	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_20150	COG1309	transcriptional regulator
AVCG678_20165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVCG678_20180	COG4770	biotin carboxylase activity
AVCG678_20195	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AVCG678_20195	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AVCG678_20225	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_20230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG678_20230	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AVCG678_20235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AVCG678_20245	COG4172	Belongs to the ABC transporter superfamily
AVCG678_20250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_20255	COG0601	transmembrane transport
AVCG678_20260	COG0747	negative chemotaxis
AVCG678_20265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_20270	COG2186	Transcriptional regulator
AVCG678_20280	COG0640	Transcriptional regulator
AVCG678_20290	COG3842	ATPase activity
AVCG678_20295	COG1175	transmembrane transport
AVCG678_20300	COG0395	ABC-type sugar transport system, permease component
AVCG678_20310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AVCG678_20320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_20325	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_20330	COG2084	Dehydrogenase
AVCG678_20340	COG3386	PFAM SMP-30 Gluconolaconase
AVCG678_20350	COG2771	luxR family
AVCG678_20360	COG0626	cystathionine gamma-synthase activity
AVCG678_20375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG678_20410	COG1175	transmembrane transport
AVCG678_20415	COG0395	ABC-type sugar transport system, permease component
AVCG678_20440	COG0446	pyridine nucleotide-disulphide oxidoreductase
AVCG678_20440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AVCG678_20445	COG4311	Sarcosine oxidase, delta subunit
AVCG678_20450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_20455	COG4977	sequence-specific DNA binding
AVCG678_20465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AVCG678_20470	COG2218	PFAM glutamate synthase alpha subunit domain protein
AVCG678_20475	COG0069	glutamate synthase activity
AVCG678_20485	COG0477	Major facilitator Superfamily
AVCG678_20490	COG1304	FMN binding
AVCG678_20505	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AVCG678_20515	COG3842	ATPase activity
AVCG678_20520	COG1175	transmembrane transport
AVCG678_20525	COG0395	ABC-type sugar transport system, permease component
AVCG678_20530	COG1609	Transcriptional regulator
AVCG678_20545	COG0412	Dienelactone hydrolase
AVCG678_20555	COG0583	DNA-binding transcription factor activity
AVCG678_20565	COG0583	DNA-binding transcription factor activity
AVCG678_20590	COG0306	phosphate transporter
AVCG678_20605	COG0277	FAD linked oxidase domain protein
AVCG678_20610	COG0277	FAD linked oxidase domain protein
AVCG678_20620	COG0247	lactate metabolic process
AVCG678_20630	COG0625	glutathione transferase activity
AVCG678_20640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AVCG678_20645	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AVCG678_20660	COG0124	histidyl-tRNA synthetase
AVCG678_20690	COG2818	Glycosylase
AVCG678_20695	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG678_20695	COG1388	LysM domain
AVCG678_20700	COG1376	ErfK ybiS ycfS ynhG family protein
AVCG678_20705	COG2909	trisaccharide binding
AVCG678_20710	COG2977	Belongs to the P-Pant transferase superfamily
AVCG678_20715	COG2137	regulation of response to DNA damage stimulus
AVCG678_20720	COG2130	NADP-dependent
AVCG678_20755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_20770	COG0196	riboflavin kinase activity
AVCG678_20780	COG2059	Chromate
AVCG678_20785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AVCG678_20790	COG0459	protein refolding
AVCG678_20820	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_20825	COG1177	transmembrane transport
AVCG678_20830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AVCG678_20835	COG0019	diaminopimelate decarboxylase activity
AVCG678_20845	COG4770	biotin carboxylase activity
AVCG678_20850	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG678_20855	COG4336	lyase activity
AVCG678_20860	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG678_20865	COG1914	H( )-stimulated, divalent metal cation uptake system
AVCG678_20870	COG1802	Transcriptional regulator
AVCG678_20875	COG1522	sequence-specific DNA binding
AVCG678_20880	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AVCG678_20905	COG0583	DNA-binding transcription factor activity
AVCG678_20910	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG678_20915	COG0511	ligase activity, forming carbon-carbon bonds
AVCG678_20920	COG0439	Biotin carboxylase
AVCG678_20930	COG1984	allophanate hydrolase subunit 2
AVCG678_20940	COG3842	ATPase activity
AVCG678_20945	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_20955	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_20960	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_20970	COG3842	ATPase activity
AVCG678_20975	COG0726	polysaccharide deacetylase
AVCG678_20985	COG0523	cobalamin synthesis protein
AVCG678_21000	COG1522	sequence-specific DNA binding
AVCG678_21010	COG0659	secondary active sulfate transmembrane transporter activity
AVCG678_21020	COG0243	molybdopterin cofactor binding
AVCG678_21030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AVCG678_21035	COG1116	anion transmembrane transporter activity
AVCG678_21040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AVCG678_21045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG678_21050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AVCG678_21055	COG3707	response regulator
AVCG678_21075	COG0583	DNA-binding transcription factor activity
AVCG678_21080	COG1960	acyl-CoA dehydrogenase activity
AVCG678_21085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVCG678_21100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AVCG678_21115	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AVCG678_21130	COG2022	thiamine diphosphate biosynthetic process
AVCG678_21290	COG0640	Transcriptional regulator
AVCG678_21295	COG0798	PFAM Bile acid sodium symporter
AVCG678_21305	COG0431	NADPH-dependent FMN reductase
AVCG678_21315	COG0745	RESPONSE REGULATOR receiver
AVCG678_21320	COG2205	protein histidine kinase activity
AVCG678_21325	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AVCG678_21335	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AVCG678_21350	COG0514	ATP-dependent DNA helicase (RecQ)
AVCG678_21360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_21365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVCG678_21370	COG1522	sequence-specific DNA binding
AVCG678_21385	COG2267	carboxylic ester hydrolase activity
AVCG678_21395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_21400	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_21415	COG1177	transmembrane transport
AVCG678_21420	COG3842	ATPase activity
AVCG678_21425	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_21435	COG4154	Belongs to the RbsD FucU family
AVCG678_21445	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_21450	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_21455	COG1129	ABC transporter
AVCG678_21475	COG2721	sulfolactate sulfo-lyase activity
AVCG678_21485	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_21500	COG0745	RESPONSE REGULATOR receiver
AVCG678_21535	COG0183	Belongs to the thiolase family
AVCG678_21540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVCG678_21550	COG1414	Transcriptional regulator
AVCG678_21565	COG0583	DNA-binding transcription factor activity
AVCG678_21575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AVCG678_21580	COG3485	protocatechuate 3,4-dioxygenase
AVCG678_21585	COG3485	protocatechuate 3,4-dioxygenase
AVCG678_21595	COG0604	alcohol dehydrogenase
AVCG678_21600	COG1674	ftsk spoiiie
AVCG678_21605	COG3842	ATPase activity
AVCG678_21620	COG0668	transmembrane transport
AVCG678_21635	COG5265	(ABC) transporter
AVCG678_21640	COG2205	protein histidine kinase activity
AVCG678_21645	COG0745	RESPONSE REGULATOR receiver
AVCG678_21660	COG3346	SURF1 family
AVCG678_21665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AVCG678_21670	COG1845	cytochrome c oxidase, subunit III
AVCG678_21675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AVCG678_21685	COG1595	DNA-templated transcription, initiation
AVCG678_21695	COG0670	Belongs to the BI1 family
AVCG678_21710	COG2273	Hydrolase Family 16
AVCG678_21710	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
AVCG678_21715	COG1301	dicarboxylic acid transport
AVCG678_21720	COG4191	Histidine kinase
AVCG678_21725	COG2204	response regulator
AVCG678_21730	COG1309	transcriptional regulator
AVCG678_21745	COG1940	carbohydrate kinase activity
AVCG678_21750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AVCG678_21755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AVCG678_21760	COG2188	Transcriptional regulator
AVCG678_21775	COG0395	ABC-type sugar transport system, permease component
AVCG678_21785	COG3842	ATPase activity
AVCG678_21810	COG0837	glucose binding
AVCG678_21810	COG1737	Transcriptional regulator
AVCG678_21815	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_21830	COG2814	Major facilitator Superfamily
AVCG678_21835	COG3142	Participates in the control of copper homeostasis
AVCG678_21855	COG0642	Histidine kinase
AVCG678_21875	COG4952	isomerase
AVCG678_21880	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_21880	COG3347	Dehydrogenase
AVCG678_21895	COG1129	ABC transporter
AVCG678_21900	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_21910	COG3254	rhamnose metabolic process
AVCG678_21920	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVCG678_21935	COG0395	ABC-type sugar transport system, permease component
AVCG678_21940	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_21950	COG3842	ATPase activity
AVCG678_21970	COG2094	Belongs to the DNA glycosylase MPG family
AVCG678_21975	COG1136	(ABC) transporter
AVCG678_21980	COG0577	efflux transmembrane transporter activity
AVCG678_21990	COG4303	Ethanolamine ammonia lyase large subunit
AVCG678_21995	COG4302	ethanolamine ammonia-lyase activity
AVCG678_22000	COG1192	Involved in chromosome partitioning
AVCG678_22005	COG1475	DNA binding
AVCG678_22010	COG0640	Transcriptional regulator
AVCG678_22015	COG2072	flavoprotein involved in K transport
AVCG678_22020	COG3706	GGDEF domain
AVCG678_22050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG678_22055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AVCG678_22065	COG3181	Tripartite tricarboxylate transporter family receptor
AVCG678_22080	COG1304	FMN binding
AVCG678_22105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AVCG678_22110	COG2814	Major facilitator Superfamily
AVCG678_22115	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_22135	COG3485	protocatechuate 3,4-dioxygenase
AVCG678_22155	COG3335	DDE superfamily endonuclease
AVCG678_22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_22245	COG3938	Belongs to the proline racemase family
AVCG678_22250	COG4176	ABC-type proline glycine betaine transport system permease component
AVCG678_22255	COG4176	ABC-type proline glycine betaine transport system permease component
AVCG678_22260	COG3448	diguanylate cyclase activity
AVCG678_22260	COG4175	Glycine betaine
AVCG678_22270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_22275	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_22280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AVCG678_22285	COG2186	Transcriptional regulator
AVCG678_22290	COG1802	Transcriptional regulator
AVCG678_22310	COG0372	Belongs to the citrate synthase family
AVCG678_22345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AVCG678_22370	COG0135	phosphoribosylanthranilate isomerase activity
AVCG678_22375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AVCG678_22380	COG0697	spore germination
AVCG678_22385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AVCG678_22395	COG2313	pseudouridylate synthase activity
AVCG678_22400	COG1902	pentaerythritol trinitrate reductase activity
AVCG678_22420	COG0583	DNA-binding transcription factor activity
AVCG678_22470	COG2205	protein histidine kinase activity
AVCG678_22475	COG0745	RESPONSE REGULATOR receiver
AVCG678_22515	COG1735	metal-dependent hydrolase with the TIM-barrel fold
AVCG678_22520	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_22535	COG1609	Transcriptional regulator
AVCG678_22550	COG0084	hydrolase, TatD family'
AVCG678_22555	COG1079	Belongs to the binding-protein-dependent transport system permease family
AVCG678_22560	COG4603	Belongs to the binding-protein-dependent transport system permease family
AVCG678_22565	COG3845	ABC transporter
AVCG678_22580	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AVCG678_22595	COG3842	ATPase activity
AVCG678_22600	COG1177	transmembrane transport
AVCG678_22605	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_22625	COG2433	Pfam Transposase IS66
AVCG678_22645	COG2226	methyltransferase
AVCG678_22670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AVCG678_22685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVCG678_22695	COG0601	transmembrane transport
AVCG678_22700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_22705	COG0444	Belongs to the ABC transporter superfamily
AVCG678_22710	COG4608	Belongs to the ABC transporter superfamily
AVCG678_22745	COG0601	transmembrane transport
AVCG678_22750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_22770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AVCG678_22780	COG2986	histidine ammonia-lyase
AVCG678_22795	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AVCG678_22805	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AVCG678_22810	COG0714	Associated with various cellular activities
AVCG678_22815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AVCG678_22890	COG2826	transposase and inactivated derivatives, IS30 family
AVCG678_22910	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AVCG678_22920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AVCG678_22945	COG2144	transferase activity, transferring acyl groups
AVCG678_22950	COG0438	transferase activity, transferring glycosyl groups
AVCG678_22960	COG2072	flavoprotein involved in K transport
AVCG678_22975	COG0243	molybdopterin cofactor binding
AVCG678_23000	COG0395	ABC-type sugar transport system, permease component
AVCG678_23015	COG1309	transcriptional regulator
AVCG678_23025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG678_23035	COG1177	transmembrane transport
AVCG678_23045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AVCG678_23060	COG0765	amino acid transport
AVCG678_23070	COG2186	Transcriptional regulator
AVCG678_23085	COG0747	negative chemotaxis
AVCG678_23090	COG0601	transmembrane transport
AVCG678_23095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_23115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AVCG678_23125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG678_23130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AVCG678_23140	COG1999	signal sequence binding
AVCG678_23150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AVCG678_23160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AVCG678_23165	COG0243	molybdopterin cofactor binding
AVCG678_23170	COG0662	Cupin 2, conserved barrel domain protein
AVCG678_23170	COG2207	Transcriptional regulator
AVCG678_23180	COG1960	acyl-CoA dehydrogenase activity
AVCG678_23215	COG3284	Transcriptional regulator
AVCG678_23220	COG1063	alcohol dehydrogenase
AVCG678_23230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG678_23240	COG0511	ligase activity, forming carbon-carbon bonds
AVCG678_23255	COG1984	allophanate hydrolase subunit 2
AVCG678_23260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AVCG678_23265	COG0436	Aminotransferase
AVCG678_23275	COG4221	oxidoreductase activity
AVCG678_23280	COG0765	amino acid transport
AVCG678_23285	COG0765	amino acid transport
AVCG678_23295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_23315	COG2181	nitrate reductase activity
AVCG678_23315	COG0247	lactate metabolic process
AVCG678_23320	COG0277	FAD linked oxidase domain protein
AVCG678_23345	COG0318	PFAM AMP-dependent synthetase and ligase
AVCG678_23355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AVCG678_23360	COG1024	Enoyl-CoA hydratase
AVCG678_23380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AVCG678_23395	COG1573	uracil-dna glycosylase
AVCG678_23425	COG0673	inositol 2-dehydrogenase activity
AVCG678_23435	COG1940	carbohydrate kinase activity
AVCG678_23440	COG3842	ATPase activity
AVCG678_23445	COG1177	transmembrane transport
AVCG678_23460	COG0383	alpha-mannosidase activity
AVCG678_23465	COG3485	protocatechuate 3,4-dioxygenase
AVCG678_23545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AVCG678_23550	COG0179	Fumarylacetoacetate (FAA) hydrolase
AVCG678_23560	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_23575	COG1960	acyl-CoA dehydrogenase activity
AVCG678_23580	COG2271	Major facilitator Superfamily
AVCG678_23590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AVCG678_23610	COG1414	Transcriptional regulator
AVCG678_23625	COG1960	acyl-CoA dehydrogenase activity
AVCG678_23635	COG1414	Transcriptional regulator
AVCG678_23640	COG0251	oxidation-reduction process
AVCG678_23650	COG2423	ornithine cyclodeaminase activity
AVCG678_23660	COG0583	DNA-binding transcription factor activity
AVCG678_23665	COG0765	amino acid transport
AVCG678_23680	COG0154	amidase activity
AVCG678_23685	COG1902	pentaerythritol trinitrate reductase activity
AVCG678_23690	COG0640	Transcriptional regulator
AVCG678_23695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AVCG678_23705	COG1780	Probably involved in ribonucleotide reductase function
AVCG678_23710	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AVCG678_23725	COG2814	Major facilitator Superfamily
AVCG678_23750	COG4214	carbohydrate transport
AVCG678_23760	COG1069	ribulokinase activity
AVCG678_23765	COG3177	Filamentation induced by cAMP protein fic
AVCG678_23770	COG0604	alcohol dehydrogenase
AVCG678_23770	COG3321	synthase
AVCG678_23785	COG1737	Transcriptional regulator
AVCG678_23790	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_23795	COG1129	ABC transporter
AVCG678_23810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG678_23820	COG0395	ABC-type sugar transport system, permease component
AVCG678_23825	COG1175	transmembrane transport
AVCG678_23835	COG3842	ATPase activity
AVCG678_23850	COG2186	Transcriptional regulator
AVCG678_23865	COG1175	transmembrane transport
AVCG678_23870	COG0395	ABC-type sugar transport system, permease component
AVCG678_23880	COG3842	ATPase activity
AVCG678_23900	COG0110	maltose O-acetyltransferase activity
AVCG678_23915	COG1175	transmembrane transport
AVCG678_23920	COG0395	ABC-type sugar transport system, permease component
AVCG678_23930	COG1940	carbohydrate kinase activity
AVCG678_23945	COG4172	Belongs to the ABC transporter superfamily
AVCG678_23950	COG0747	negative chemotaxis
AVCG678_23960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_23965	COG2362	D-Aminopeptidase
AVCG678_23985	COG0840	transmembrane signaling receptor activity
AVCG678_24010	COG0534	Mate efflux family protein
AVCG678_24030	COG0318	PFAM AMP-dependent synthetase and ligase
AVCG678_24040	COG2226	methyltransferase
AVCG678_24090	COG4774	siderophore transport
AVCG678_24090	COG1629	transport
AVCG678_24095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AVCG678_24100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG678_24105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AVCG678_24110	COG1120	ATPase activity
AVCG678_24185	COG0601	transmembrane transport
AVCG678_24190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_24195	COG4608	Belongs to the ABC transporter superfamily
AVCG678_24200	COG1349	DNA-binding transcription factor activity
AVCG678_24205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG678_24240	COG1475	DNA binding
AVCG678_24245	COG0640	Transcriptional regulator
AVCG678_24410	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_24420	COG1012	belongs to the aldehyde dehydrogenase family
AVCG678_24430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AVCG678_24435	COG3284	Transcriptional regulator
AVCG678_24440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AVCG678_24445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_24455	COG3842	ATPase activity
AVCG678_24460	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_24465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_24475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AVCG678_24485	COG0601	transmembrane transport
AVCG678_24525	COG1609	Transcriptional regulator
AVCG678_24535	COG2826	transposase and inactivated derivatives, IS30 family
AVCG678_24560	COG2814	Major facilitator Superfamily
AVCG678_24565	COG3181	Tripartite tricarboxylate transporter family receptor
AVCG678_24590	COG2159	amidohydrolase
AVCG678_24595	COG0583	DNA-binding transcription factor activity
AVCG678_24600	COG1301	dicarboxylic acid transport
AVCG678_24605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG678_24625	COG1473	amidohydrolase
AVCG678_24660	COG3547	Transposase (IS116 IS110 IS902 family)
AVCG678_24695	COG0601	transmembrane transport
AVCG678_24705	COG2188	Transcriptional regulator
AVCG678_24710	COG2222	sugar isomerase
AVCG678_24715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AVCG678_24725	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
AVCG678_24730	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AVCG678_24740	COG0436	Aminotransferase
AVCG678_24760	COG0187	DNA topoisomerase II activity
AVCG678_24765	COG0187	DNA topoisomerase II activity
AVCG678_24790	COG2188	Transcriptional regulator
AVCG678_24795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AVCG678_24810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_24815	COG4172	Belongs to the ABC transporter superfamily
AVCG678_24825	COG0006	proline dipeptidase activity
AVCG678_24860	COG0655	NAD(P)H dehydrogenase (quinone) activity
AVCG678_24895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AVCG678_24905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AVCG678_24940	COG0583	DNA-binding transcription factor activity
AVCG678_24990	COG0835	chemotaxis
AVCG678_24995	COG2201	protein-glutamate methylesterase activity
AVCG678_25000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG678_25005	COG0643	Histidine kinase
AVCG678_25005	COG0784	Response regulator, receiver
AVCG678_25005	COG2198	Histidine kinase
AVCG678_25015	COG0784	Response regulator, receiver
AVCG678_25015	COG2198	Histidine kinase
AVCG678_25015	COG2205	protein histidine kinase activity
AVCG678_25065	COG0784	Response regulator, receiver
AVCG678_25065	COG4191	Histidine kinase
AVCG678_25090	COG0784	Response regulator, receiver
AVCG678_25090	COG4191	Histidine kinase
AVCG678_25155	COG0840	transmembrane signaling receptor activity
AVCG678_25190	COG0840	transmembrane signaling receptor activity
AVCG678_25205	COG4251	negative regulation of phosphorylation
AVCG678_25215	COG0840	transmembrane signaling receptor activity
AVCG678_25215	COG2972	Histidine kinase
AVCG678_25230	COG5002	protein histidine kinase activity
AVCG678_25240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AVCG678_25245	COG2205	protein histidine kinase activity
AVCG678_25245	COG3437	response regulator, receiver
AVCG678_25245	COG3850	Histidine kinase
AVCG678_25245	COG4999	Histidine kinase
AVCG678_25270	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AVCG678_25330	COG3265	gluconokinase activity
AVCG678_25335	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_25340	COG1129	ABC transporter
AVCG678_25345	COG1172	Belongs to the binding-protein-dependent transport system permease family
AVCG678_25365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AVCG678_25370	COG1609	Transcriptional regulator
AVCG678_25425	COG2826	transposase and inactivated derivatives, IS30 family
AVCG678_25435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVCG678_25445	COG4215	(ABC) transporter
AVCG678_25450	COG4598	ABC transporter
AVCG678_25470	COG2207	Transcriptional regulator
AVCG678_25570	COG3831	ATPase activity
AVCG678_25575	COG0776	regulation of translation
AVCG678_25580	COG5489	Protein of unknown function (DUF736)
AVCG678_25590	COG0300	oxidoreductase activity
AVCG678_25605	COG1475	DNA binding
AVCG678_25650	COG2814	Major facilitator Superfamily
AVCG678_25655	COG0583	DNA-binding transcription factor activity
AVCG678_25675	COG0444	Belongs to the ABC transporter superfamily
AVCG678_25685	COG0747	negative chemotaxis
AVCG678_25705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_25710	COG3938	Belongs to the proline racemase family
AVCG678_25725	COG3938	Belongs to the proline racemase family
AVCG678_25730	COG1802	Transcriptional regulator
AVCG678_25750	COG1473	amidohydrolase
AVCG678_25755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AVCG678_25770	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_25775	COG1028	Short-chain dehydrogenase reductase Sdr
AVCG678_25850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVCG678_25875	COG3701	Conjugal transfer protein
AVCG678_25880	COG3846	protein secretion by the type IV secretion system
AVCG678_25890	COG5314	conjugation
AVCG678_25895	COG3451	type IV secretory pathway VirB4
AVCG678_25910	COG4962	Type ii secretion system protein e
AVCG678_25925	COG1475	DNA binding
AVCG678_25930	COG0640	Transcriptional regulator
AVCG678_25960	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AVCG678_25985	COG4297	protein containing double-stranded beta helix domain
AVCG678_26145	COG1396	sequence-specific DNA binding
AVCG678_26220	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AVCG678_26290	COG4974	Belongs to the 'phage' integrase family
AVCG678_26295	COG0582	viral genome integration into host DNA
AVCG678_26300	COG0582	viral genome integration into host DNA
AVCG678_26315	COG5489	Protein of unknown function (DUF736)
AVCG678_26325	COG0776	regulation of translation
AVCG678_26330	COG3831	ATPase activity
AVCG678_26395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AVCG678_26400	COG1522	sequence-specific DNA binding
AVCG678_26415	COG3842	ATPase activity
AVCG678_26420	COG1177	transmembrane transport
AVCG678_26425	COG1177	transmembrane transport
AVCG678_26435	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_26440	COG1177	transmembrane transport
AVCG678_26445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AVCG678_26450	COG3842	ATPase activity
AVCG678_26460	COG0747	negative chemotaxis
AVCG678_26470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AVCG678_26490	COG1176	ABC-type spermidine putrescine transport system, permease component I
AVCG678_26500	COG1840	ABC-type Fe3 transport system, periplasmic component
AVCG678_26525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_26530	COG4172	Belongs to the ABC transporter superfamily
AVCG678_26540	COG1064	alcohol dehydrogenase
AVCG678_26580	COG1192	Involved in chromosome partitioning
AVCG678_26600	COG3293	Transposase
AVCG678_26615	COG3415	Transposase
AVCG678_26645	COG1192	Involved in chromosome partitioning
AVCG678_26655	COG0745	RESPONSE REGULATOR receiver
AVCG678_26730	COG4372	Transposase
AVCG678_26785	COG3293	Transposase
AVCG678_26805	COG4372	Transposase
AVCG678_26820	COG4974	Belongs to the 'phage' integrase family
AVCG678_26855	COG0582	viral genome integration into host DNA
AVCG678_26935	COG3328	transposase activity
AVCG678_27020	COG4149	molybdate abc transporter
AVCG678_27025	COG1177	transmembrane transport
AVCG678_27030	COG3842	ATPase activity
AVCG678_27035	COG1840	ABC-type Fe3 transport system, periplasmic component
AVCG678_27045	COG4172	Belongs to the ABC transporter superfamily
AVCG678_27050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AVCG678_27055	COG0601	transmembrane transport
AVCG678_27060	COG4166	transmembrane transport
AVCG678_27115	COG3701	Conjugal transfer protein
AVCG678_27120	COG3846	protein secretion by the type IV secretion system
AVCG678_27130	COG5314	conjugation
AVCG678_27135	COG3451	type IV secretory pathway VirB4
AVCG678_27150	COG4962	Type ii secretion system protein e