locus-tag	class	description
K4831_00005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K4831_00010	COG0424	maF-like protein
K4831_00015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K4831_00020	COG0237	dephospho-CoA kinase activity
K4831_00030	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K4831_00045	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
K4831_00085	COG0135	phosphoribosylanthranilate isomerase activity
K4831_00090	COG0133	tryptophan synthase activity
K4831_00095	COG0159	tryptophan synthase activity
K4831_00100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K4831_00105	COG0285	dihydrofolate synthase activity
K4831_00115	COG2226	methyltransferase
K4831_00130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K4831_00135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K4831_00140	COG0131	Imidazoleglycerol-phosphate dehydratase
K4831_00145	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K4831_00150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K4831_00155	COG0107	imidazoleglycerol-phosphate synthase activity
K4831_00160	COG0140	phosphoribosyl-ATP diphosphatase activity
K4831_00165	COG1072	(Pantothenic acid kinase))
K4831_00180	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K4831_00185	COG0745	RESPONSE REGULATOR receiver
K4831_00190	COG0642	Histidine kinase
K4831_00200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
K4831_00200	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K4831_00205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K4831_00210	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K4831_00215	COG2205	protein histidine kinase activity
K4831_00220	COG3178	'Phosphotransferase
K4831_00225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K4831_00235	COG1074	ATP-dependent DNA helicase activity
K4831_00240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K4831_00255	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
K4831_00265	COG1643	Atp-dependent helicase
K4831_00270	COG2423	ornithine cyclodeaminase activity
K4831_00310	COG2963	transposase activity
K4831_00335	COG2814	Major facilitator Superfamily
K4831_00340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K4831_00345	COG1609	Transcriptional regulator
K4831_00355	COG0673	inositol 2-dehydrogenase activity
K4831_00365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K4831_00370	COG3962	Belongs to the TPP enzyme family
K4831_00385	COG3718	enzyme involved in inositol metabolism
K4831_00410	COG4221	oxidoreductase activity
K4831_00415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K4831_00430	COG1595	DNA-templated transcription, initiation
K4831_00435	COG3806	Anti-sigma factor
K4831_00455	COG3842	ATPase activity
K4831_00460	COG3842	ATPase activity
K4831_00470	COG0395	ABC-type sugar transport system, permease component
K4831_00485	COG3474	cytochrome
K4831_00490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K4831_00495	COG0077	Prephenate dehydratase
K4831_00495	COG1605	Chorismate mutase
K4831_00505	COG2816	NAD+ diphosphatase activity
K4831_00520	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K4831_00525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K4831_00545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K4831_00550	COG0481	GTPase activity
K4831_00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K4831_00570	COG1607	acyl-coa hydrolase
K4831_00595	COG1393	Belongs to the ArsC family
K4831_00600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K4831_00605	COG2309	aminopeptidase activity
K4831_00620	COG1278	Cold shock
K4831_00625	COG1570	exodeoxyribonuclease VII activity
K4831_00665	COG0667	Aldo Keto reductase
K4831_00675	COG2814	Major facilitator Superfamily
K4831_00680	COG0583	DNA-binding transcription factor activity
K4831_00690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K4831_00695	COG2951	lytic endotransglycosylase activity
K4831_00715	COG2814	Major facilitator Superfamily
K4831_00725	COG0779	Required for maturation of 30S ribosomal subunits
K4831_00730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K4831_00730	COG0195	Participates in both transcription termination and antitermination
K4831_00740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K4831_00745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K4831_00750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K4831_00755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K4831_00760	COG1185	polyribonucleotide nucleotidyltransferase activity
K4831_00770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K4831_00780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K4831_00790	COG2860	membrane
K4831_00800	COG0477	Major facilitator Superfamily
K4831_00815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K4831_00820	COG0539	negative regulation of cytoplasmic translation
K4831_00840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K4831_00855	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K4831_00860	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K4831_00865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K4831_00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K4831_00880	COG0072	phenylalanine-tRNA ligase activity
K4831_00925	COG4964	Belongs to the GSP D family
K4831_00965	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K4831_00970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K4831_00975	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K4831_00985	COG0588	phosphoglycerate mutase activity
K4831_00990	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K4831_00995	COG1132	(ABC) transporter
K4831_01000	COG0837	glucose binding
K4831_01005	COG1803	Methylglyoxal synthase
K4831_01010	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
K4831_01015	COG4166	transmembrane transport
K4831_01020	COG4174	ABC transporter (Permease)
K4831_01025	COG4239	(ABC) transporter, permease
K4831_01030	COG4172	Belongs to the ABC transporter superfamily
K4831_01045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K4831_01070	COG1802	Transcriptional regulator
K4831_01070	COG4626	Terminase
K4831_01140	COG1744	ABC transporter substrate-binding protein PnrA-like
K4831_01145	COG3845	ABC transporter
K4831_01150	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_01155	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_01170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K4831_01175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K4831_01180	COG2188	Transcriptional regulator
K4831_01185	COG3624	Phosphonate C-P lyase system protein PhnG
K4831_01190	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
K4831_01195	COG3626	phosphonate metabolism
K4831_01200	COG3627	carbon phosphorus lyase activity
K4831_01205	COG4107	phosphonate C-P lyase system protein PhnK
K4831_01210	COG4778	phosphonate C-P lyase system protein PhnL
K4831_01220	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
K4831_01225	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
K4831_01235	COG3639	organic phosphonate transmembrane transporter activity
K4831_01240	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
K4831_01245	COG3454	Phosphonate metabolism
K4831_01250	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
K4831_01265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K4831_01270	COG2353	YceI-like domain
K4831_01275	COG2353	YceI-like domain
K4831_01285	COG0791	NLP P60 protein
K4831_01290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K4831_01290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K4831_01300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K4831_01305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K4831_01320	COG0443	Heat shock 70 kDa protein
K4831_01330	COG0484	heat shock protein binding
K4831_01335	COG2900	Belongs to the SlyX family
K4831_01340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K4831_01355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K4831_01365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K4831_01370	COG5001	Diguanylate cyclase
K4831_01370	COG3300	MHYT domain
K4831_01375	COG3002	Belongs to the UPF0753 family
K4831_01400	COG0519	Catalyzes the synthesis of GMP from XMP
K4831_01400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K4831_01445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K4831_01455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K4831_01465	COG1968	undecaprenyl-diphosphatase activity
K4831_01490	COG0284	orotidine-5'-phosphate decarboxylase activity
K4831_01500	COG3963	phosphatidate phosphatase activity
K4831_01510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K4831_01515	COG0792	nuclease activity
K4831_01525	COG1175	transmembrane transport
K4831_01530	COG0395	ABC-type sugar transport system, permease component
K4831_01535	COG3842	ATPase activity
K4831_01545	COG0189	ligase activity
K4831_01550	COG0606	chelatase, subunit chli
K4831_01565	COG1280	lysine exporter protein (LysE YggA)
K4831_01570	COG0756	dUTP diphosphatase activity
K4831_01575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K4831_01580	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K4831_01585	COG1877	trehalose-phosphatase activity
K4831_01605	COG1741	Belongs to the pirin family
K4831_01615	COG0583	DNA-binding transcription factor activity
K4831_01630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K4831_01635	COG3920	Histidine kinase
K4831_01640	COG0784	Response regulator, receiver
K4831_01645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K4831_01645	COG2205	protein histidine kinase activity
K4831_01645	COG0784	Response regulator, receiver
K4831_01645	COG2198	Histidine kinase
K4831_01650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K4831_01655	COG2226	methyltransferase
K4831_01660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K4831_01665	COG0268	Binds directly to 16S ribosomal RNA
K4831_01670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K4831_01675	COG0697	spore germination
K4831_01680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K4831_01685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K4831_01690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K4831_01700	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K4831_01705	COG1420	regulation of RNA biosynthetic process
K4831_01710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K4831_01715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K4831_01720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K4831_01730	COG1137	ATPase activity
K4831_01735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K4831_01745	COG0776	regulation of translation
K4831_01760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K4831_01765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K4831_01785	COG0583	DNA-binding transcription factor activity
K4831_01790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K4831_01795	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K4831_01805	COG0346	lactoylglutathione lyase activity
K4831_01810	COG0180	Tryptophanyl-tRNA synthetase
K4831_01820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K4831_01825	COG1214	PFAM Peptidase M22, glycoprotease
K4831_01845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K4831_01850	COG1702	phosphate starvation-inducible protein PhoH
K4831_01855	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K4831_01860	COG4535	Mg2 and Co2 transporter CorC
K4831_01865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K4831_01870	COG1396	sequence-specific DNA binding
K4831_01875	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K4831_01880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K4831_01890	COG0071	Belongs to the small heat shock protein (HSP20) family
K4831_01910	COG0840	transmembrane signaling receptor activity
K4831_01920	COG2205	protein histidine kinase activity
K4831_01925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K4831_01930	COG0594	ribonuclease P activity
K4831_01935	COG0706	membrane insertase activity
K4831_01940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K4831_01945	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K4831_01960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K4831_01965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K4831_01990	COG2171	N-acyltransferase activity
K4831_01995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K4831_02020	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K4831_02025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K4831_02035	COG0745	RESPONSE REGULATOR receiver
K4831_02040	COG0704	Plays a role in the regulation of phosphate uptake
K4831_02045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K4831_02055	COG0573	inorganic phosphate transmembrane transporter activity
K4831_02065	COG5002	protein histidine kinase activity
K4831_02070	COG2326	polyphosphate kinase activity
K4831_02090	COG1125	glycine betaine transport
K4831_02090	COG0517	IMP dehydrogenase activity
K4831_02095	COG1174	glycine betaine transport
K4831_02110	COG2188	Transcriptional regulator
K4831_02115	COG2986	histidine ammonia-lyase
K4831_02125	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K4831_02130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K4831_02130	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K4831_02140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K4831_02160	COG0427	acetyl-CoA hydrolase
K4831_02170	COG3938	Belongs to the proline racemase family
K4831_02175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K4831_02180	COG0745	RESPONSE REGULATOR receiver
K4831_02200	COG0418	dihydroorotase activity
K4831_02205	COG3706	GGDEF domain
K4831_02210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K4831_02220	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_02225	COG0166	Belongs to the GPI family
K4831_02230	COG0318	PFAM AMP-dependent synthetase and ligase
K4831_02245	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_02255	COG0101	tRNA pseudouridine synthase activity
K4831_02260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K4831_02265	COG0242	peptide deformylase activity
K4831_02270	COG2967	ApaG domain
K4831_02280	COG0717	Belongs to the dCTP deaminase family
K4831_02325	COG0250	Participates in transcription elongation, termination and antitermination
K4831_02350	COG1450	Type ii and iii secretion system protein
K4831_02360	COG2165	general secretion pathway protein
K4831_02385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K4831_02440	COG0587	DNA-directed DNA polymerase activity
K4831_02460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K4831_02485	COG0167	dihydroorotate dehydrogenase activity
K4831_02505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K4831_02525	COG1024	Enoyl-CoA hydratase
K4831_02525	COG1250	3-hydroxyacyl-CoA dehydrogenase
K4831_02530	COG0183	Belongs to the thiolase family
K4831_02535	COG1960	acyl-CoA dehydrogenase activity
K4831_02555	COG1785	Belongs to the alkaline phosphatase family
K4831_02565	COG1136	(ABC) transporter
K4831_02580	COG2203	Gaf domain
K4831_02580	COG3706	GGDEF domain
K4831_02580	COG4251	negative regulation of phosphorylation
K4831_02580	COG5001	Diguanylate cyclase
K4831_02585	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K4831_02595	COG1201	RNA secondary structure unwinding
K4831_02615	COG1047	Peptidyl-prolyl cis-trans
K4831_02620	COG0784	Response regulator, receiver
K4831_02620	COG2198	Histidine kinase
K4831_02620	COG2205	protein histidine kinase activity
K4831_02625	COG1970	mechanosensitive ion channel activity
K4831_02630	COG0436	Aminotransferase
K4831_02635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K4831_02655	COG1216	Glycosyl transferase, family 2
K4831_02680	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K4831_02685	COG0424	maF-like protein
K4831_02690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K4831_02700	COG5328	Belongs to the UPF0262 family
K4831_02705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K4831_02715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K4831_02750	COG1215	transferase activity, transferring glycosyl groups
K4831_02760	COG0488	(ABC) transporter
K4831_02785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K4831_02790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K4831_02795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K4831_02800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K4831_02805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K4831_02810	COG4786	Flagellar basal body rod
K4831_02815	COG1157	protein secretion by the type III secretion system
K4831_02825	COG1815	bacterial-type flagellum-dependent cell motility
K4831_02830	COG1558	bacterial-type flagellum-dependent cell motility
K4831_02835	COG1677	Flagellar hook-basal body complex protein FliE
K4831_02840	COG4786	Flagellar basal body rod
K4831_02845	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
K4831_02850	COG1706	bacterial-type flagellum-dependent cell motility
K4831_02860	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K4831_02870	COG1338	Plays a role in the flagellum-specific transport system
K4831_02875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_02880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_02885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_02890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_02895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_02905	COG1360	Flagellar Motor Protein
K4831_02930	COG1749	Flagellar hook protein flgE
K4831_02950	COG5443	negative regulation of bacterial-type flagellum assembly
K4831_02955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K4831_02960	COG4794	Type iii secretion
K4831_02965	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K4831_03000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K4831_03005	COG1609	Transcriptional regulator
K4831_03010	COG1653	transport
K4831_03015	COG1175	transmembrane transport
K4831_03020	COG0395	ABC-type sugar transport system, permease component
K4831_03025	COG0366	Alpha amylase catalytic
K4831_03030	COG3842	ATPase activity
K4831_03045	COG3493	citrate carrier protein
K4831_03055	COG0129	dihydroxy-acid dehydratase activity
K4831_03060	COG0363	glucosamine-6-phosphate deaminase activity
K4831_03065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K4831_03070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_03080	COG2081	HI0933 family
K4831_03095	COG0840	transmembrane signaling receptor activity
K4831_03095	COG2972	Histidine kinase
K4831_03100	COG0583	DNA-binding transcription factor activity
K4831_03125	COG2224	Isocitrate lyase
K4831_03140	COG3842	ATPase activity
K4831_03145	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_03150	COG1177	transmembrane transport
K4831_03160	COG2205	protein histidine kinase activity
K4831_03210	COG1959	2 iron, 2 sulfur cluster binding
K4831_03215	COG3265	gluconokinase activity
K4831_03220	COG2134	cdp-diacylglycerol pyrophosphatase
K4831_03225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_03230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K4831_03250	COG0579	oxidoreductase
K4831_03255	COG0446	pyridine nucleotide-disulphide oxidoreductase
K4831_03270	COG0248	Ppx GppA phosphatase
K4831_03275	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K4831_03285	COG3300	MHYT domain
K4831_03285	COG5001	Diguanylate cyclase
K4831_03290	COG0784	Response regulator, receiver
K4831_03290	COG2198	Histidine kinase
K4831_03290	COG5002	protein histidine kinase activity
K4831_03295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K4831_03305	COG1663	tetraacyldisaccharide 4'-kinase activity
K4831_03315	COG1519	Transferase
K4831_03325	COG1218	3'(2'),5'-bisphosphate nucleotidase
K4831_03330	COG0312	modulator of DNA gyrase
K4831_03335	COG0475	glutathione-regulated potassium exporter activity
K4831_03335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K4831_03345	COG0742	ribosomal rna small subunit methyltransferase
K4831_03350	COG1187	pseudouridine synthase activity
K4831_03355	COG0590	tRNA wobble adenosine to inosine editing
K4831_03365	COG0477	Major facilitator Superfamily
K4831_03375	COG3386	PFAM SMP-30 Gluconolaconase
K4831_03385	COG2771	luxR family
K4831_03405	COG3158	transport of potassium into the cell
K4831_03415	COG0356	it plays a direct role in the translocation of protons across the membrane
K4831_03425	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K4831_03430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K4831_03435	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K4831_03450	COG0521	Mo-molybdopterin cofactor biosynthetic process
K4831_03455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K4831_03465	COG0142	geranyltranstransferase activity
K4831_03475	COG4106	trans-aconitate 2-methyltransferase activity
K4831_03495	COG0752	glycyl-tRNA synthetase alpha subunit
K4831_03505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K4831_03510	COG0751	glycine-tRNA ligase activity
K4831_03515	COG1683	Conserved Protein
K4831_03520	COG0840	transmembrane signaling receptor activity
K4831_03520	COG0840	transmembrane signaling receptor activity
K4831_03530	COG0151	Belongs to the GarS family
K4831_03540	COG2183	response to ionizing radiation
K4831_03545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K4831_03575	COG0725	ABC transporter, periplasmic molybdate-binding protein
K4831_03580	COG4149	molybdate abc transporter
K4831_03585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K4831_03590	COG2005	Transcriptional regulator
K4831_03590	COG3585	molybdate ion transport
K4831_03600	COG0009	L-threonylcarbamoyladenylate synthase
K4831_03610	COG0840	transmembrane signaling receptor activity
K4831_03615	COG4638	Rieske (2fe-2S)
K4831_03640	COG1960	acyl-CoA dehydrogenase activity
K4831_03645	COG1024	Enoyl-CoA hydratase
K4831_03655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K4831_03665	COG0840	transmembrane signaling receptor activity
K4831_03670	COG0840	transmembrane signaling receptor activity
K4831_03675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K4831_03680	COG1722	exodeoxyribonuclease VII activity
K4831_03685	COG0123	including yeast histone deacetylase and acetoin utilization protein
K4831_03700	COG1268	BioY protein
K4831_03705	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K4831_03710	COG1122	ATPase activity
K4831_03720	COG3214	Protein conserved in bacteria
K4831_03745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K4831_03745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K4831_03750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K4831_03755	COG5001	Diguanylate cyclase
K4831_03755	COG3300	MHYT domain
K4831_03770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K4831_03775	COG0484	heat shock protein binding
K4831_03785	COG0259	pyridoxamine-phosphate oxidase activity
K4831_03795	COG2814	Major facilitator Superfamily
K4831_03800	COG0789	Transcriptional regulator
K4831_03805	COG1686	Belongs to the peptidase S11 family
K4831_03820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K4831_03830	COG0312	modulator of DNA gyrase
K4831_03845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K4831_03850	COG0109	protoheme IX farnesyltransferase activity
K4831_03860	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K4831_03875	COG3346	SURF1 family
K4831_03885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K4831_03895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K4831_03900	COG0328	RNA-DNA hybrid ribonuclease activity
K4831_03910	COG0803	Belongs to the bacterial solute-binding protein 9 family
K4831_03925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K4831_03925	COG0678	peroxiredoxin activity
K4831_03935	COG1678	Uncharacterized ACR, COG1678
K4831_03945	COG0640	Transcriptional regulator
K4831_03950	COG5001	Diguanylate cyclase
K4831_03955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K4831_03960	COG0612	Peptidase, M16
K4831_03975	COG1597	lipid kinase activity
K4831_03980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K4831_03990	COG2189	Belongs to the N(4) N(6)-methyltransferase family
K4831_04020	COG1194	a g-specific adenine glycosylase
K4831_04035	COG1196	nuclear chromosome segregation
K4831_04050	COG2814	Major facilitator Superfamily
K4831_04065	COG0574	Belongs to the PEP-utilizing enzyme family
K4831_04065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K4831_04100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K4831_04120	COG0840	transmembrane signaling receptor activity
K4831_04125	COG0175	sulfate reduction
K4831_04130	COG0175	sulfate reduction
K4831_04135	COG2895	sulfate adenylyltransferase (ATP) activity
K4831_04155	COG1609	Transcriptional regulator
K4831_04165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K4831_04175	COG0693	protein deglycase activity
K4831_04190	COG0038	chloride channel
K4831_04195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_04220	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K4831_04230	COG1012	belongs to the aldehyde dehydrogenase family
K4831_04235	COG0625	glutathione transferase activity
K4831_04245	COG1309	transcriptional regulator
K4831_04250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
K4831_04260	COG0840	transmembrane signaling receptor activity
K4831_04265	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
K4831_04285	COG1349	DNA-binding transcription factor activity
K4831_04330	COG0477	Major facilitator Superfamily
K4831_04340	COG0778	Nitroreductase
K4831_04365	COG1376	ErfK ybiS ycfS ynhG family protein
K4831_04365	COG1388	LysM domain
K4831_04370	COG1376	ErfK ybiS ycfS ynhG family protein
K4831_04375	COG1846	Transcriptional regulator
K4831_04380	COG1764	response to oxidative stress
K4831_04405	COG3265	gluconokinase activity
K4831_04415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K4831_04420	COG0840	transmembrane signaling receptor activity
K4831_04425	COG0840	transmembrane signaling receptor activity
K4831_04435	COG0433	COG0433 Predicted ATPase
K4831_04440	COG1473	amidohydrolase
K4831_04445	COG0840	transmembrane signaling receptor activity
K4831_04450	COG1968	undecaprenyl-diphosphatase activity
K4831_04460	COG4214	carbohydrate transport
K4831_04470	COG4213	ABC transporter substrate-binding protein
K4831_04475	COG1940	carbohydrate kinase activity
K4831_04475	COG1846	Transcriptional regulator
K4831_04495	COG1120	ATPase activity
K4831_04500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K4831_04515	COG2226	methyltransferase
K4831_04535	COG2010	Cytochrome c
K4831_04555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K4831_04560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K4831_04565	COG1733	regulation of RNA biosynthetic process
K4831_04570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K4831_04580	COG5001	Diguanylate cyclase
K4831_04580	COG5002	protein histidine kinase activity
K4831_04580	COG3447	MASE1 domain protein
K4831_04585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K4831_04630	COG2514	catechol 2,3-dioxygenase activity
K4831_04645	COG3788	relative of glutathione S-transferase, MAPEG superfamily
K4831_04650	COG1272	protein, Hemolysin III
K4831_04655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K4831_04675	COG4957	zinc ion binding
K4831_04680	COG1320	monovalent cation:proton antiporter activity
K4831_04685	COG2212	antiporter activity
K4831_04690	COG1863	multisubunit Na H antiporter MnhE subunit
K4831_04695	COG0651	ATP synthesis coupled electron transport
K4831_04700	COG1006	Multisubunit Na H antiporter MnhC subunit
K4831_04705	COG2111	Na H antiporter
K4831_04710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K4831_04710	COG2111	Na H antiporter
K4831_04715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K4831_04735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K4831_04740	COG0577	efflux transmembrane transporter activity
K4831_04740	COG1136	(ABC) transporter
K4831_04760	COG2166	iron-sulfur cluster assembly
K4831_04770	COG2205	protein histidine kinase activity
K4831_04785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K4831_04850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K4831_04855	COG2983	Belongs to the UPF0260 family
K4831_04870	COG0789	Transcriptional regulator
K4831_04900	COG4695	Portal protein
K4831_05010	COG4520	surface antigen
K4831_05015	COG4235	cytochrome complex assembly
K4831_05020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K4831_05025	COG1138	Cytochrome C-type biogenesis protein
K4831_05030	COG3088	subunit of a heme lyase
K4831_05040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K4831_05045	COG0745	RESPONSE REGULATOR receiver
K4831_05050	COG2205	protein histidine kinase activity
K4831_05055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K4831_05060	COG2202	Pas domain
K4831_05060	COG2205	protein histidine kinase activity
K4831_05065	COG0308	aminopeptidase N
K4831_05070	COG0840	transmembrane signaling receptor activity
K4831_05070	COG3290	protein histidine kinase activity
K4831_05105	COG0443	Heat shock 70 kDa protein
K4831_05120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K4831_05135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K4831_05140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K4831_05145	COG2239	Acts as a magnesium transporter
K4831_05150	COG2814	Major facilitator Superfamily
K4831_05165	COG4172	Belongs to the ABC transporter superfamily
K4831_05170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_05175	COG0601	transmembrane transport
K4831_05180	COG4166	transmembrane transport
K4831_05185	COG0174	glutamine synthetase
K4831_05200	COG1695	Transcriptional regulator
K4831_05205	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K4831_05210	COG0463	Glycosyl transferase, family 2
K4831_05220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K4831_05230	COG0625	glutathione transferase activity
K4831_05290	COG0741	lytic transglycosylase activity
K4831_05295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K4831_05300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K4831_05310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K4831_05310	COG2169	Transcriptional regulator
K4831_05315	COG0840	transmembrane signaling receptor activity
K4831_05325	COG1758	RNA polymerase activity
K4831_05340	COG0681	Belongs to the peptidase S26 family
K4831_05345	COG0571	ribonuclease III activity
K4831_05350	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K4831_05355	COG3180	Ammonia monooxygenase
K4831_05360	COG1381	Involved in DNA repair and RecF pathway recombination
K4831_05375	COG1418	mRNA catabolic process
K4831_05390	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
K4831_05415	COG1051	belongs to the nudix hydrolase family
K4831_05430	COG1183	phosphatidylcholine synthase activity
K4831_05435	COG0688	phosphatidylethanolamine metabolic process
K4831_05440	COG5265	(ABC) transporter
K4831_05445	COG2823	Periplasmic or secreted lipoprotein
K4831_05445	COG1652	LysM domain
K4831_05460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K4831_05500	COG0215	cysteine-tRNA ligase activity
K4831_05505	COG5434	Belongs to the glycosyl hydrolase 28 family
K4831_05510	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
K4831_05515	COG1088	dTDP-glucose 4,6-dehydratase activity
K4831_05520	COG1091	dTDP-4-dehydrorhamnose reductase activity
K4831_05525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K4831_05540	COG4221	oxidoreductase activity
K4831_05545	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K4831_05550	COG1286	toxin biosynthetic process
K4831_05555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K4831_05560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K4831_05575	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K4831_05580	COG0765	amino acid transport
K4831_05585	COG0765	amino acid transport
K4831_05595	COG0305	Participates in initiation and elongation during chromosome replication
K4831_05600	COG0359	binds to the 23S rRNA
K4831_05610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K4831_05615	COG0360	Binds together with S18 to 16S ribosomal RNA
K4831_05635	COG0667	Aldo Keto reductase
K4831_05640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K4831_05650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K4831_05655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K4831_05660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K4831_05665	COG1561	YicC-like family, N-terminal region
K4831_05670	COG0194	GDP metabolic process
K4831_05675	COG0500	methyltransferase
K4831_05680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K4831_05685	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K4831_05695	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K4831_05710	COG0671	phosphoesterase, PA-phosphatase related
K4831_05715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K4831_05730	COG1505	serine-type exopeptidase activity
K4831_05735	COG0488	(ABC) transporter
K4831_05750	COG0105	UTP biosynthetic process
K4831_05755	COG0314	molybdopterin synthase activity
K4831_05765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K4831_05770	COG0322	excinuclease ABC activity
K4831_05775	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_05785	COG0625	glutathione transferase activity
K4831_05790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K4831_05795	COG0243	molybdopterin cofactor binding
K4831_05805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K4831_05805	COG3453	Protein conserved in bacteria
K4831_05810	COG0640	Transcriptional regulator
K4831_05820	COG2391	methyltransferase activity
K4831_05825	COG0730	response to heat
K4831_05830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K4831_05835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K4831_05840	COG0628	permease
K4831_05850	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K4831_05855	COG0248	Ppx GppA phosphatase
K4831_05860	COG1321	iron dependent repressor
K4831_05865	COG1914	H( )-stimulated, divalent metal cation uptake system
K4831_05885	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K4831_05900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K4831_05915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K4831_05920	COG3300	MHYT domain
K4831_05920	COG5001	Diguanylate cyclase
K4831_05930	COG2199	diguanylate cyclase activity
K4831_05930	COG2200	EAL domain
K4831_05930	COG2203	Gaf domain
K4831_05935	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K4831_05945	COG0113	porphobilinogen synthase activity
K4831_05965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K4831_05970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K4831_05975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K4831_05975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K4831_05990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K4831_05995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K4831_06000	COG2814	Major facilitator Superfamily
K4831_06005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K4831_06025	COG0416	fatty acid biosynthetic process
K4831_06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K4831_06035	COG0776	regulation of translation
K4831_06060	COG0582	viral genome integration into host DNA
K4831_06090	COG3436	PFAM IS66 Orf2 family protein
K4831_06175	COG2963	transposase activity
K4831_06185	COG4372	Transposase
K4831_06195	COG3209	COG3209 Rhs family protein
K4831_06210	COG3209	COG3209 Rhs family protein
K4831_06250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K4831_06290	COG1484	DNA-dependent DNA replication
K4831_06295	COG4584	PFAM Integrase catalytic
K4831_06365	COG1612	heme a metabolic process
K4831_06370	COG3384	dioxygenase
K4831_06380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K4831_06385	COG0010	Belongs to the arginase family
K4831_06400	COG2329	Antibiotic biosynthesis monooxygenase
K4831_06405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K4831_06410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K4831_06415	COG1832	CoA-binding protein
K4831_06425	COG1832	CoA-binding protein
K4831_06435	COG1408	metallophosphoesterase
K4831_06445	COG2124	cytochrome p450
K4831_06455	COG0740	serine-type endopeptidase activity
K4831_06460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K4831_06465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K4831_06495	COG1024	Enoyl-CoA hydratase
K4831_06515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K4831_06520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K4831_06525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K4831_06530	COG0649	NAD binding
K4831_06540	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
K4831_06545	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K4831_06550	COG0052	Belongs to the universal ribosomal protein uS2 family
K4831_06560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K4831_06565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K4831_06575	COG0713	ATP synthesis coupled electron transport
K4831_06590	COG1007	ATP synthesis coupled electron transport
K4831_06605	COG0346	lactoylglutathione lyase activity
K4831_06620	COG0442	prolyl-tRNA aminoacylation
K4831_06630	COG1136	(ABC) transporter
K4831_06645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K4831_06660	COG0784	Response regulator, receiver
K4831_06670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K4831_06675	COG0477	Major facilitator Superfamily
K4831_06685	COG0557	exoribonuclease II activity
K4831_06690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K4831_06700	COG0758	DNA mediated transformation
K4831_06705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K4831_06715	COG0540	Belongs to the ATCase OTCase family
K4831_06720	COG1960	acyl-CoA dehydrogenase activity
K4831_06755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K4831_06760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K4831_06765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K4831_06770	COG0154	amidase activity
K4831_06785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K4831_06790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K4831_06790	COG3952	Lipid A Biosynthesis
K4831_06800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K4831_06820	COG4765	Protein conserved in bacteria
K4831_06825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K4831_06835	COG0511	ligase activity, forming carbon-carbon bonds
K4831_06840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K4831_06845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K4831_06850	COG0436	Aminotransferase
K4831_06860	COG1530	ribonuclease E activity
K4831_06865	COG0860	N-Acetylmuramoyl-L-alanine amidase
K4831_06870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K4831_06880	COG0284	orotidine-5'-phosphate decarboxylase activity
K4831_06890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K4831_06915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K4831_06930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K4831_06955	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K4831_06965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K4831_06970	COG0081	regulation of translation
K4831_06975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K4831_06980	COG0222	ribosome binding
K4831_06985	COG0085	RNA polymerase activity
K4831_06990	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K4831_07005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K4831_07010	COG0049	tRNA binding
K4831_07015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K4831_07020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K4831_07025	COG0051	transcription antitermination factor activity, RNA binding
K4831_07030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K4831_07035	COG0088	Forms part of the polypeptide exit tunnel
K4831_07040	COG0089	rRNA binding
K4831_07045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K4831_07050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K4831_07055	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K4831_07060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K4831_07065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K4831_07070	COG0255	Belongs to the universal ribosomal protein uL29 family
K4831_07075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K4831_07080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K4831_07085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K4831_07090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K4831_07095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K4831_07100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K4831_07105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K4831_07110	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K4831_07115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K4831_07120	COG1841	ribosomal large subunit assembly
K4831_07125	COG0200	Binds to the 23S rRNA
K4831_07130	COG0201	protein transport
K4831_07135	COG0563	adenylate kinase activity
K4831_07140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K4831_07145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K4831_07150	COG0202	RNA polymerase activity
K4831_07155	COG0203	ribosomal protein L17
K4831_07170	COG2897	thiosulfate sulfurtransferase activity
K4831_07180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K4831_07185	COG0415	Belongs to the DNA photolyase family
K4831_07195	COG0739	heme binding
K4831_07200	COG2833	Protein of unknown function (DUF455)
K4831_07210	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K4831_07235	COG0281	malic enzyme
K4831_07235	COG0280	phosphate acetyltransferase
K4831_07245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K4831_07250	COG1127	ABC transporter
K4831_07260	COG3218	ABC-type transport auxiliary lipoprotein component
K4831_07260	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K4831_07265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K4831_07285	COG0047	phosphoribosylformylglycinamidine synthase activity
K4831_07290	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K4831_07295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K4831_07310	COG3706	GGDEF domain
K4831_07320	COG0538	isocitrate dehydrogenase activity
K4831_07325	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
K4831_07330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K4831_07340	COG1253	flavin adenine dinucleotide binding
K4831_07350	COG0657	acetylesterase activity
K4831_07350	COG2755	lipolytic protein G-D-S-L family
K4831_07355	COG2195	Cleaves the N-terminal amino acid of tripeptides
K4831_07370	COG0861	Integral membrane protein TerC family
K4831_07375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K4831_07380	COG2066	Belongs to the glutaminase family
K4831_07390	COG0037	tRNA processing
K4831_07395	COG0483	inositol monophosphate 1-phosphatase activity
K4831_07400	COG0483	inositol monophosphate 1-phosphatase activity
K4831_07405	COG2814	Major facilitator Superfamily
K4831_07410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K4831_07425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K4831_07430	COG0484	heat shock protein binding
K4831_07440	COG0321	lipoyl(octanoyl) transferase activity
K4831_07580	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K4831_07690	COG0463	Glycosyl transferase, family 2
K4831_07690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K4831_07705	COG4372	Transposase
K4831_07715	COG2963	transposase activity
K4831_07735	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K4831_07740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K4831_07770	COG0242	peptide deformylase activity
K4831_07780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K4831_07785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K4831_07790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K4831_07795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K4831_07800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K4831_07825	COG0823	Involved in the tonB-independent uptake of proteins
K4831_07830	COG0778	Nitroreductase
K4831_07840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K4831_07845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K4831_07865	COG2205	protein histidine kinase activity
K4831_07865	COG2202	Pas domain
K4831_07875	COG1573	uracil-dna glycosylase
K4831_07880	COG1522	sequence-specific DNA binding
K4831_07885	COG2084	Dehydrogenase
K4831_07900	COG5425	PFAM Usg family protein
K4831_07925	COG1763	Mo-molybdopterin cofactor biosynthetic process
K4831_07930	COG0746	molybdenum cofactor guanylyltransferase activity
K4831_07940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K4831_07950	COG3706	GGDEF domain
K4831_07965	COG0114	fumarate hydratase activity
K4831_07970	COG2989	Protein conserved in bacteria
K4831_07975	COG0546	phosphoglycolate phosphatase activity
K4831_07980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K4831_07995	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K4831_08030	COG4251	negative regulation of phosphorylation
K4831_08030	COG5001	Diguanylate cyclase
K4831_08030	COG3706	GGDEF domain
K4831_08030	COG2203	Gaf domain
K4831_08035	COG0556	nucleotide-excision repair
K4831_08055	COG3161	chorismate lyase activity
K4831_08065	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K4831_08070	COG0148	phosphopyruvate hydratase activity
K4831_08080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K4831_08085	COG0022	dehydrogenase e1 component
K4831_08085	COG0508	dehydrogenase complex catalyzes the overall conversion of
K4831_08090	COG0508	dehydrogenase complex catalyzes the overall conversion of
K4831_08105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K4831_08115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K4831_08135	COG0477	Major facilitator Superfamily
K4831_08140	COG2867	negative regulation of translational initiation
K4831_08145	COG1546	Belongs to the CinA family
K4831_08145	COG1058	Belongs to the CinA family
K4831_08150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K4831_08150	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K4831_08165	COG2204	response regulator
K4831_08170	COG5000	phosphorelay sensor kinase activity
K4831_08175	COG2204	response regulator
K4831_08180	COG1923	regulation of RNA biosynthetic process
K4831_08185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K4831_08195	COG3956	TIGRFAM MazG family protein
K4831_08205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K4831_08205	COG1648	precorrin-2 dehydrogenase activity
K4831_08230	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_08240	COG1686	Belongs to the peptidase S11 family
K4831_08245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K4831_08255	COG0730	response to heat
K4831_08260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K4831_08265	COG0084	hydrolase, TatD family'
K4831_08270	COG0321	lipoyl(octanoyl) transferase activity
K4831_08270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K4831_08285	COG0785	Cytochrome C biogenesis protein
K4831_08290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K4831_08295	COG1183	phosphatidylcholine synthase activity
K4831_08300	COG3845	ABC transporter
K4831_08305	COG4603	Belongs to the binding-protein-dependent transport system permease family
K4831_08310	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_08320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K4831_08325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K4831_08365	COG0523	cobalamin synthesis protein
K4831_08375	COG1121	(ABC) transporter
K4831_08380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K4831_08385	COG0735	belongs to the Fur family
K4831_08405	COG1686	Belongs to the peptidase S11 family
K4831_08440	COG1752	Esterase of the alpha-beta hydrolase superfamily
K4831_08445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K4831_08450	COG0302	gtp cyclohydrolase
K4831_08460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K4831_08470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K4831_08485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K4831_08490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K4831_08535	COG0187	DNA topoisomerase II activity
K4831_08550	COG0149	triose-phosphate isomerase activity
K4831_08560	COG0504	CTP synthase activity
K4831_08585	COG0633	Ferredoxin
K4831_08595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K4831_08630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K4831_08630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K4831_08635	COG0509	glycine decarboxylation via glycine cleavage system
K4831_08640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K4831_08660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K4831_08665	COG0564	pseudouridine synthase activity
K4831_08670	COG0546	phosphoglycolate phosphatase activity
K4831_08685	COG0477	Major facilitator Superfamily
K4831_08700	COG2003	Belongs to the UPF0758 family
K4831_08705	COG0024	Methionine aminopeptidase
K4831_08715	COG2855	membrane
K4831_08720	COG1489	DNA binding
K4831_08725	COG3243	poly(R)-hydroxyalkanoic acid synthase
K4831_08735	COG0436	Aminotransferase
K4831_08745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K4831_08770	COG0346	lactoylglutathione lyase activity
K4831_08775	COG1278	Cold shock
K4831_08805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K4831_08815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K4831_08825	COG0697	spore germination
K4831_08850	COG0174	glutamine synthetase
K4831_08855	COG0347	Belongs to the P(II) protein family
K4831_08860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K4831_08860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K4831_08875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K4831_08880	COG0629	single-stranded DNA binding
K4831_08890	COG2095	MarC family integral membrane protein
K4831_08895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K4831_08925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K4831_08940	COG1653	transport
K4831_08945	COG1175	transmembrane transport
K4831_08950	COG0395	ABC-type sugar transport system, permease component
K4831_08955	COG3842	ATPase activity
K4831_08975	COG0667	Aldo Keto reductase
K4831_08980	COG3507	Belongs to the glycosyl hydrolase 43 family
K4831_08995	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
K4831_09000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K4831_09005	COG0129	dihydroxy-acid dehydratase activity
K4831_09025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K4831_09050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K4831_09075	COG0513	Belongs to the DEAD box helicase family
K4831_09080	COG1280	lysine exporter protein (LysE YggA)
K4831_09085	COG2945	thiolester hydrolase activity
K4831_09090	COG1104	cysteine desulfurase activity
K4831_09095	COG0719	Fe-S assembly protein
K4831_09105	COG0396	ATPase activity
K4831_09110	COG0719	Fe-S assembly protein
K4831_09120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K4831_09125	COG2151	metal-sulfur cluster biosynthetic enzyme
K4831_09140	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K4831_09155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K4831_09160	COG0343	queuine tRNA-ribosyltransferase activity
K4831_09170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K4831_09180	COG2826	transposase and inactivated derivatives, IS30 family
K4831_09185	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
K4831_09190	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K4831_09195	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K4831_09200	COG2080	2 iron, 2 sulfur cluster binding
K4831_09230	COG2062	phosphohistidine phosphatase, SixA
K4831_09235	COG3106	COG3106 Predicted ATPase
K4831_09240	COG3768	UPF0283 membrane protein
K4831_09255	COG0436	Aminotransferase
K4831_09265	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K4831_09270	COG0544	peptidyl-prolyl cis-trans isomerase activity
K4831_09300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K4831_09305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K4831_09325	COG0252	asparaginase activity
K4831_09335	COG0737	Belongs to the 5'-nucleotidase family
K4831_09345	COG0463	Glycosyl transferase, family 2
K4831_09350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K4831_09365	COG1116	anion transmembrane transporter activity
K4831_09370	COG3665	Urea carboxylase-associated protein
K4831_09380	COG4770	biotin carboxylase activity
K4831_09400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K4831_09405	COG2153	protein acetylation
K4831_09410	COG1671	Belongs to the UPF0178 family
K4831_09420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K4831_09425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K4831_09435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K4831_09440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K4831_09445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K4831_09450	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K4831_09455	COG0750	zinc metalloprotease
K4831_09465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K4831_09470	COG0233	cytoplasmic translational termination
K4831_09475	COG0528	UMP kinase activity
K4831_09480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K4831_09485	COG0052	Belongs to the universal ribosomal protein uS2 family
K4831_09510	COG0537	adenosine 5'-monophosphoramidase activity
K4831_09530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K4831_09555	COG2267	carboxylic ester hydrolase activity
K4831_09575	COG0626	cystathionine gamma-synthase activity
K4831_09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K4831_09585	COG4597	amino acid ABC transporter
K4831_09590	COG0765	amino acid transport
K4831_09595	COG1126	abc transporter atp-binding protein
K4831_09605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K4831_09610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K4831_09620	COG2313	pseudouridylate synthase activity
K4831_09625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K4831_09630	COG0658	competence protein
K4831_09630	COG2333	competence protein COMEC
K4831_09635	COG0372	Belongs to the citrate synthase family
K4831_09645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K4831_09650	COG0134	indole-3-glycerol-phosphate synthase activity
K4831_09655	COG0315	cyclic pyranopterin monophosphate synthase activity
K4831_09660	COG0303	'Molybdopterin
K4831_09665	COG0671	phosphoesterase, PA-phosphatase related
K4831_09670	COG1492	cobalamin metabolic process
K4831_09680	COG4176	ABC-type proline glycine betaine transport system permease component
K4831_09685	COG0517	IMP dehydrogenase activity
K4831_09685	COG4175	Glycine betaine
K4831_09705	COG3698	Phosphodiester glycosidase
K4831_09730	COG0583	DNA-binding transcription factor activity
K4831_09760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K4831_09780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K4831_09790	COG0840	transmembrane signaling receptor activity
K4831_09800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K4831_09810	COG1546	Belongs to the CinA family
K4831_09810	COG1058	Belongs to the CinA family
K4831_09815	COG2972	Histidine kinase
K4831_09815	COG0840	transmembrane signaling receptor activity
K4831_09825	COG0835	chemotaxis
K4831_09835	COG1760	l-serine dehydratase
K4831_09860	COG2239	Acts as a magnesium transporter
K4831_09885	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
K4831_09890	COG2099	Precorrin-6x reductase
K4831_09895	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
K4831_09905	COG2875	Belongs to the precorrin methyltransferase family
K4831_09985	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K4831_10010	COG1862	Preprotein translocase
K4831_10025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K4831_10030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K4831_10035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K4831_10040	COG0805	protein transport
K4831_10050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K4831_10055	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K4831_10060	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K4831_10065	COG1472	Belongs to the glycosyl hydrolase 3 family
K4831_10075	COG0018	arginyl-trna synthetase
K4831_10080	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K4831_10085	COG0316	Belongs to the HesB IscA family
K4831_10105	COG0525	valine-tRNA ligase activity
K4831_10120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K4831_10160	COG4608	Belongs to the ABC transporter superfamily
K4831_10220	COG0842	Transport permease protein
K4831_10225	COG1131	(ABC) transporter
K4831_10235	COG0745	RESPONSE REGULATOR receiver
K4831_10250	COG2226	methyltransferase
K4831_10255	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K4831_10255	COG3264	Mechanosensitive ion channel
K4831_10275	COG4558	Periplasmic binding protein
K4831_10280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K4831_10285	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K4831_10325	COG2963	transposase activity
K4831_10415	COG1082	Xylose isomerase domain protein TIM barrel
K4831_10420	COG0438	transferase activity, transferring glycosyl groups
K4831_10425	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_10430	COG1063	alcohol dehydrogenase
K4831_10435	COG1940	carbohydrate kinase activity
K4831_10450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K4831_10460	COG3328	transposase activity
K4831_10505	COG0384	phenazine biosynthesis protein PhzF
K4831_10520	COG0789	Transcriptional regulator
K4831_10525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K4831_10535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K4831_10550	COG1522	sequence-specific DNA binding
K4831_10555	COG1794	racemase activity, acting on amino acids and derivatives
K4831_10560	COG1309	transcriptional regulator
K4831_10565	COG2814	Major facilitator Superfamily
K4831_10575	COG1733	regulation of RNA biosynthetic process
K4831_10585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K4831_10590	COG0789	Transcriptional regulator
K4831_10595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K4831_10605	COG0656	L-ascorbic acid biosynthetic process
K4831_10620	COG0028	Belongs to the TPP enzyme family
K4831_10640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K4831_10645	COG0560	Phosphoserine phosphatase
K4831_10645	COG3830	Belongs to the UPF0237 family
K4831_10660	COG0330	HflC and HflK could
K4831_10675	COG2259	Doxx family
K4831_10680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K4831_10715	COG0277	FAD linked oxidase domain protein
K4831_10720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K4831_10725	COG0581	inorganic phosphate transmembrane transporter activity
K4831_10730	COG0573	inorganic phosphate transmembrane transporter activity
K4831_10735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K4831_10755	COG4993	Dehydrogenase
K4831_10760	COG1335	isochorismatase
K4831_10765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K4831_10770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K4831_10780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K4831_10815	COG2264	protein methyltransferase activity
K4831_10820	COG1999	signal sequence binding
K4831_10825	COG0840	transmembrane signaling receptor activity
K4831_10830	COG0835	chemotaxis
K4831_10845	COG2176	DNA-directed DNA polymerase activity
K4831_10855	COG0840	transmembrane signaling receptor activity
K4831_10860	COG0456	acetyltransferase
K4831_10895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K4831_10905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K4831_10915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K4831_10925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K4831_10930	COG0849	cell division
K4831_10935	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K4831_10940	COG1181	Belongs to the D-alanine--D-alanine ligase family
K4831_10945	COG0477	Major facilitator Superfamily
K4831_10950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K4831_10955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K4831_10960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K4831_10970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K4831_10975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K4831_10985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K4831_11000	COG0275	rRNA processing
K4831_11005	COG2001	Belongs to the MraZ family
K4831_11025	COG3023	N-Acetylmuramoyl-L-alanine amidase
K4831_11090	COG2226	methyltransferase
K4831_11100	COG0840	transmembrane signaling receptor activity
K4831_11105	COG0840	transmembrane signaling receptor activity
K4831_11105	COG2972	Histidine kinase
K4831_11120	COG2267	carboxylic ester hydrolase activity
K4831_11125	COG0697	spore germination
K4831_11130	COG0028	Belongs to the TPP enzyme family
K4831_11140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K4831_11145	COG0251	oxidation-reduction process
K4831_11160	COG1376	ErfK ybiS ycfS ynhG family protein
K4831_11185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K4831_11190	COG4149	molybdate abc transporter
K4831_11195	COG3842	ATPase activity
K4831_11210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K4831_11215	COG2197	response regulator
K4831_11220	COG1396	sequence-specific DNA binding
K4831_11285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K4831_11290	COG0697	spore germination
K4831_11300	COG2968	Membrane
K4831_11310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K4831_11380	COG1278	Cold shock
K4831_11415	COG0432	Pfam Uncharacterised protein family UPF0047
K4831_11420	COG5001	Diguanylate cyclase
K4831_11420	COG4251	negative regulation of phosphorylation
K4831_11420	COG3706	GGDEF domain
K4831_11420	COG2203	Gaf domain
K4831_11430	COG0583	DNA-binding transcription factor activity
K4831_11445	COG1473	amidohydrolase
K4831_11465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K4831_11490	COG0505	Belongs to the CarA family
K4831_11495	COG0534	Mate efflux family protein
K4831_11500	COG0583	DNA-binding transcription factor activity
K4831_11505	COG0667	Aldo Keto reductase
K4831_11510	COG2321	neutral zinc metallopeptidase
K4831_11525	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K4831_11535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K4831_11570	COG1522	sequence-specific DNA binding
K4831_11575	COG0492	ferredoxin-NADP+ reductase activity
K4831_11580	COG0583	DNA-binding transcription factor activity
K4831_11585	COG0640	Transcriptional regulator
K4831_11590	COG1902	pentaerythritol trinitrate reductase activity
K4831_11610	COG0387	Pfam Sodium calcium exchanger
K4831_11620	COG0436	Aminotransferase
K4831_11635	COG1278	Cold shock
K4831_11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K4831_11650	COG1846	Transcriptional regulator
K4831_11655	COG0745	RESPONSE REGULATOR receiver
K4831_11660	COG2205	protein histidine kinase activity
K4831_11665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K4831_11685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K4831_11700	COG0006	proline dipeptidase activity
K4831_11720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K4831_11735	COG1012	belongs to the aldehyde dehydrogenase family
K4831_11745	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K4831_11760	COG0193	aminoacyl-tRNA hydrolase activity
K4831_11770	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K4831_11775	COG0012	GTP binding
K4831_11795	COG0386	Belongs to the glutathione peroxidase family
K4831_11810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K4831_11815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K4831_11815	COG2857	Cytochrome c1
K4831_11840	COG1132	(ABC) transporter
K4831_11845	COG1132	(ABC) transporter
K4831_11850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K4831_11860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K4831_11870	COG0408	coproporphyrinogen oxidase activity
K4831_11885	COG0617	tRNA 3'-terminal CCA addition
K4831_11900	COG0714	Associated with various cellular activities
K4831_11925	COG0454	-acetyltransferase
K4831_11945	COG0435	Glutathione S-transferase
K4831_11960	COG0740	serine-type endopeptidase activity
K4831_11965	COG3135	benzoate transporter
K4831_11970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K4831_11980	COG4115	mRNA cleavage
K4831_12035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K4831_12035	COG0512	Glutamine amidotransferase of anthranilate synthase
K4831_12045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K4831_12050	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K4831_12070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K4831_12085	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K4831_12095	COG2197	response regulator
K4831_12110	COG1435	thymidine kinase activity
K4831_12125	COG4175	Glycine betaine
K4831_12140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K4831_12175	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K4831_12185	COG4115	mRNA cleavage
K4831_12190	COG0366	Alpha amylase catalytic
K4831_12200	COG1160	GTP binding
K4831_12220	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
K4831_12235	COG0024	Methionine aminopeptidase
K4831_12240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_12245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K4831_12250	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_12260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K4831_12270	COG0457	Tetratricopeptide repeat
K4831_12275	COG0583	DNA-binding transcription factor activity
K4831_12285	COG0402	S-adenosylhomocysteine deaminase activity
K4831_12290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K4831_12300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_12305	COG0137	argininosuccinate synthase activity
K4831_12340	COG2351	hydroxyisourate hydrolase activity
K4831_12345	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
K4831_12350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K4831_12355	COG0174	glutamine synthetase
K4831_12365	COG3195	allantoin biosynthetic process
K4831_12365	COG3648	Uricase
K4831_12370	COG1064	alcohol dehydrogenase
K4831_12385	COG3706	GGDEF domain
K4831_12400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_12405	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K4831_12405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_12420	COG0513	Belongs to the DEAD box helicase family
K4831_12435	COG1733	regulation of RNA biosynthetic process
K4831_12545	COG2308	Evidence 4 Homologs of previously reported genes of
K4831_12560	COG2346	COG2346, Truncated hemoglobins
K4831_12580	COG0493	'glutamate synthase
K4831_12600	COG1309	transcriptional regulator
K4831_12610	COG2852	Protein conserved in bacteria
K4831_12630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_12635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_12640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K4831_12665	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K4831_12670	COG0830	nickel cation binding
K4831_12675	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
K4831_12680	COG5001	Diguanylate cyclase
K4831_12680	COG5002	protein histidine kinase activity
K4831_12700	COG0804	urea catabolic process
K4831_12705	COG1442	glycosyl transferase family 8
K4831_12710	COG3755	Protein conserved in bacteria
K4831_12715	COG0832	Belongs to the urease beta subunit family
K4831_12720	COG3813	Protein conserved in bacteria
K4831_12725	COG0831	urea catabolic process
K4831_12730	COG0829	nickel cation binding
K4831_12775	COG4251	negative regulation of phosphorylation
K4831_12785	COG0784	Response regulator, receiver
K4831_12785	COG2205	protein histidine kinase activity
K4831_12830	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
K4831_12835	COG2894	cell division
K4831_12840	COG0850	regulation of cytokinetic process
K4831_12885	COG2814	Major facilitator Superfamily
K4831_12895	COG1218	3'(2'),5'-bisphosphate nucleotidase
K4831_12950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K4831_12960	COG0564	pseudouridine synthase activity
K4831_12965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K4831_12965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_12970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K4831_12985	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K4831_13000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K4831_13010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K4831_13030	COG1116	anion transmembrane transporter activity
K4831_13040	COG0402	S-adenosylhomocysteine deaminase activity
K4831_13075	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K4831_13110	COG1175	transmembrane transport
K4831_13135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K4831_13145	COG0482	sulfurtransferase activity
K4831_13155	COG4774	siderophore transport
K4831_13175	COG1120	ATPase activity
K4831_13185	COG4774	siderophore transport
K4831_13215	COG1294	oxidase, subunit
K4831_13220	COG1271	oxidase subunit
K4831_13225	COG0840	transmembrane signaling receptor activity
K4831_13230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K4831_13255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_13260	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K4831_13265	COG0632	four-way junction helicase activity
K4831_13270	COG2002	toxin-antitoxin pair type II binding
K4831_13280	COG2255	four-way junction helicase activity
K4831_13285	COG1408	metallophosphoesterase
K4831_13290	COG0494	nUDIX hydrolase
K4831_13305	COG0824	Thioesterase
K4831_13325	COG0823	Involved in the tonB-independent uptake of proteins
K4831_13330	COG2885	chlorophyll binding
K4831_13340	COG0037	tRNA processing
K4831_13345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K4831_13350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K4831_13355	COG0217	transcriptional regulatory protein
K4831_13425	COG0840	transmembrane signaling receptor activity
K4831_13430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K4831_13435	COG1692	metallophosphoesterase
K4831_13440	COG0126	phosphoglycerate kinase activity
K4831_13445	COG3588	fructose-bisphosphate aldolase
K4831_13450	COG0384	phenazine biosynthesis protein PhzF
K4831_13480	COG0254	rRNA binding
K4831_13485	COG1132	(ABC) transporter
K4831_13510	COG0483	inositol monophosphate 1-phosphatase activity
K4831_13520	COG0352	thiamine-phosphate diphosphorylase activity
K4831_13530	COG0640	Transcriptional regulator
K4831_13545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K4831_13550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K4831_13555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K4831_13560	COG0457	Tetratricopeptide repeat
K4831_13565	COG0596	Alpha beta hydrolase
K4831_13570	COG0469	pyruvate kinase activity
K4831_13590	COG3750	Belongs to the UPF0335 family
K4831_13595	COG0583	DNA-binding transcription factor activity
K4831_13600	COG0679	Auxin Efflux Carrier
K4831_13620	COG0512	Glutamine amidotransferase of anthranilate synthase
K4831_13620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K4831_13625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K4831_13635	COG5310	Homospermidine synthase
K4831_13645	COG0737	Belongs to the 5'-nucleotidase family
K4831_13650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K4831_13660	COG0840	transmembrane signaling receptor activity
K4831_13665	COG0602	queuosine metabolic process
K4831_13670	COG0720	synthase
K4831_13675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K4831_13680	COG0330	HflC and HflK could
K4831_13690	COG0517	IMP dehydrogenase activity
K4831_13690	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K4831_13700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K4831_13705	COG2951	lytic endotransglycosylase activity
K4831_13715	COG0840	transmembrane signaling receptor activity
K4831_13725	COG0070	glutamate synthase
K4831_13725	COG0067	glutamate synthase
K4831_13725	COG0069	glutamate synthase activity
K4831_13735	COG0071	Belongs to the small heat shock protein (HSP20) family
K4831_13770	COG0668	transmembrane transport
K4831_13775	COG0662	Cupin 2, conserved barrel domain protein
K4831_13775	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
K4831_13785	COG2308	Evidence 4 Homologs of previously reported genes of
K4831_13785	COG2307	Protein conserved in bacteria
K4831_13805	COG0058	SHG alpha-glucan phosphorylase activity
K4831_13810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K4831_13815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K4831_13820	COG0297	glycogen (starch) synthase activity
K4831_13825	COG0033	Phosphoglucomutase
K4831_13830	COG1523	belongs to the glycosyl hydrolase 13 family
K4831_13865	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K4831_13870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_13880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K4831_13880	COG0446	pyridine nucleotide-disulphide oxidoreductase
K4831_13895	COG1733	regulation of RNA biosynthetic process
K4831_13915	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K4831_13920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K4831_13925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K4831_13930	COG1609	Transcriptional regulator
K4831_13935	COG1846	Transcriptional regulator
K4831_13945	COG0523	cobalamin synthesis protein
K4831_13955	COG0840	transmembrane signaling receptor activity
K4831_13960	COG3047	cAMP biosynthetic process
K4831_13985	COG0583	DNA-binding transcription factor activity
K4831_14015	COG0800	Aldolase
K4831_14020	COG2954	triphosphatase activity
K4831_14030	COG2378	regulation of single-species biofilm formation
K4831_14040	COG1054	Belongs to the UPF0176 family
K4831_14045	COG2202	Pas domain
K4831_14045	COG2200	EAL domain
K4831_14045	COG2199	diguanylate cyclase activity
K4831_14065	COG0673	inositol 2-dehydrogenase activity
K4831_14075	COG2115	Belongs to the xylose isomerase family
K4831_14080	COG1070	Carbohydrate kinase
K4831_14085	COG1609	Transcriptional regulator
K4831_14100	COG1309	transcriptional regulator
K4831_14105	COG1253	flavin adenine dinucleotide binding
K4831_14125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K4831_14145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K4831_14165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K4831_14170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K4831_14175	COG0471	metal ion transport
K4831_14175	COG3273	potassium ion transport
K4831_14190	COG2274	protein secretion by the type I secretion system
K4831_14225	COG4172	Belongs to the ABC transporter superfamily
K4831_14230	COG1473	amidohydrolase
K4831_14245	COG0601	transmembrane transport
K4831_14250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_14255	COG0842	Transport permease protein
K4831_14260	COG0842	Transport permease protein
K4831_14260	COG1129	ABC transporter
K4831_14265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K4831_14275	COG3454	Phosphonate metabolism
K4831_14290	COG0444	Belongs to the ABC transporter superfamily
K4831_14295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_14300	COG0601	transmembrane transport
K4831_14305	COG0747	negative chemotaxis
K4831_14315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K4831_14320	COG1802	Transcriptional regulator
K4831_14325	COG1904	glucuronate isomerase
K4831_14330	COG1917	Cupin 2, conserved barrel domain protein
K4831_14340	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_14345	COG0246	Mannitol dehydrogenase
K4831_14350	COG1312	Catalyzes the dehydration of D-mannonate
K4831_14355	COG2721	sulfolactate sulfo-lyase activity
K4831_14365	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K4831_14380	COG4213	ABC transporter substrate-binding protein
K4831_14390	COG4214	carbohydrate transport
K4831_14400	COG0129	dihydroxy-acid dehydratase activity
K4831_14415	COG3734	2-keto-3-deoxy-galactonokinase
K4831_14420	COG0800	Aldolase
K4831_14425	COG2832	Protein of unknown function (DUF454)
K4831_14430	COG0697	spore germination
K4831_14435	COG2186	Transcriptional regulator
K4831_14440	COG2807	transmembrane transport
K4831_14445	COG2373	Large extracellular alpha-helical protein
K4831_14450	COG4953	penicillin-binding protein 1C
K4831_14455	COG0840	transmembrane signaling receptor activity
K4831_14455	COG2972	Histidine kinase
K4831_14460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K4831_14465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K4831_14470	COG0438	transferase activity, transferring glycosyl groups
K4831_14480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_14485	COG0601	transmembrane transport
K4831_14490	COG0747	negative chemotaxis
K4831_14510	COG0438	transferase activity, transferring glycosyl groups
K4831_14530	COG1132	(ABC) transporter
K4831_14540	COG0419	ATPase involved in DNA repair
K4831_14545	COG0840	transmembrane signaling receptor activity
K4831_14555	COG4372	Transposase
K4831_14565	COG2963	transposase activity
K4831_14610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K4831_14620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K4831_14625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K4831_14635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K4831_14650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K4831_14660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K4831_14690	COG0438	transferase activity, transferring glycosyl groups
K4831_14705	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K4831_14715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K4831_14730	COG1793	dna ligase
K4831_14750	COG0783	Belongs to the Dps family
K4831_14760	COG0784	Response regulator, receiver
K4831_14800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K4831_14815	COG0848	biopolymer transport protein
K4831_14825	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K4831_14840	COG0010	Belongs to the arginase family
K4831_14860	COG1940	carbohydrate kinase activity
K4831_14880	COG1072	(Pantothenic acid kinase))
K4831_14890	COG0765	amino acid transport
K4831_14895	COG0765	amino acid transport
K4831_14900	COG4598	ABC transporter
K4831_14915	COG0402	S-adenosylhomocysteine deaminase activity
K4831_14920	COG1228	amidohydrolase
K4831_14925	COG2986	histidine ammonia-lyase
K4831_14935	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K4831_14955	COG1289	transmembrane transporter activity
K4831_14980	COG0346	lactoylglutathione lyase activity
K4831_15005	COG3307	-O-antigen
K4831_15010	COG1596	polysaccharide export
K4831_15015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K4831_15025	COG1215	transferase activity, transferring glycosyl groups
K4831_15030	COG2327	Polysaccharide pyruvyl transferase
K4831_15035	COG0463	Glycosyl transferase, family 2
K4831_15040	COG2244	polysaccharide biosynthetic process
K4831_15050	COG2273	Hydrolase Family 16
K4831_15055	COG0438	transferase activity, transferring glycosyl groups
K4831_15060	COG1215	transferase activity, transferring glycosyl groups
K4831_15065	COG1215	transferase activity, transferring glycosyl groups
K4831_15070	COG1215	transferase activity, transferring glycosyl groups
K4831_15075	COG0489	protein tyrosine kinase activity
K4831_15075	COG3206	protein involved in exopolysaccharide biosynthesis
K4831_15080	COG0469	pyruvate kinase activity
K4831_15125	COG0542	response to heat
K4831_15135	COG2890	protein-(glutamine-N5) methyltransferase activity
K4831_15140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K4831_15150	COG0527	aspartate kinase activity
K4831_15155	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
K4831_15155	COG0392	lysyltransferase activity
K4831_15170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K4831_15185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K4831_15190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K4831_15200	COG2226	methyltransferase
K4831_15215	COG0494	nUDIX hydrolase
K4831_15225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K4831_15230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K4831_15235	COG0653	protein targeting
K4831_15250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K4831_15300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K4831_15310	COG0300	oxidoreductase activity
K4831_15325	COG2086	electron transfer activity
K4831_15335	COG2972	Histidine kinase
K4831_15335	COG0840	transmembrane signaling receptor activity
K4831_15340	COG1250	3-hydroxyacyl-CoA dehydrogenase
K4831_15345	COG0625	glutathione transferase activity
K4831_15350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K4831_15355	COG0165	Argininosuccinate lyase
K4831_15365	COG0019	diaminopimelate decarboxylase activity
K4831_15380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K4831_15390	COG2884	Cell division ATP-binding protein ftsE
K4831_15410	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
K4831_15420	COG0287	Prephenate dehydrogenase
K4831_15425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K4831_15430	COG2226	methyltransferase
K4831_15435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K4831_15460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K4831_15465	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K4831_15495	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K4831_15500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K4831_15510	COG4974	Belongs to the 'phage' integrase family
K4831_15515	COG0825	malonyl-CoA metabolic process
K4831_15520	COG3034	peptidoglycan biosynthetic process
K4831_15530	COG0523	cobalamin synthesis protein
K4831_15535	COG1686	Belongs to the peptidase S11 family
K4831_15540	COG1473	amidohydrolase
K4831_15550	COG0628	permease
K4831_15560	COG2771	luxR family
K4831_15565	COG1766	The M ring may be actively involved in energy transduction
K4831_15575	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
K4831_15580	COG0745	RESPONSE REGULATOR receiver
K4831_15585	COG2201	protein-glutamate methylesterase activity
K4831_15590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K4831_15595	COG0835	chemotaxis
K4831_15600	COG0643	Histidine kinase
K4831_15600	COG2198	Histidine kinase
K4831_15605	COG0745	RESPONSE REGULATOR receiver
K4831_15615	COG0840	transmembrane signaling receptor activity
K4831_15620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K4831_15630	COG0156	8-amino-7-oxononanoate synthase activity
K4831_15640	COG0729	surface antigen
K4831_15655	COG0835	chemotaxis
K4831_15660	COG2223	nitrite transmembrane transporter activity
K4831_15670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K4831_15675	COG3383	formate dehydrogenase (NAD+) activity
K4831_15690	COG0583	DNA-binding transcription factor activity
K4831_15695	COG0640	Transcriptional regulator
K4831_15700	COG0039	L-malate dehydrogenase activity
K4831_15705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K4831_15710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K4831_15715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K4831_15720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K4831_15725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K4831_15740	COG2972	Histidine kinase
K4831_15740	COG0840	transmembrane signaling receptor activity
K4831_15745	COG4974	Belongs to the 'phage' integrase family
K4831_15770	COG0508	dehydrogenase complex catalyzes the overall conversion of
K4831_15780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K4831_15790	COG0045	succinate-CoA ligase (ADP-forming) activity
K4831_15795	COG0039	L-malate dehydrogenase activity
K4831_15800	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K4831_15845	COG2350	Protein conserved in bacteria
K4831_15850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K4831_15855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K4831_15860	COG0181	hydroxymethylbilane synthase activity
K4831_15900	COG1872	DUF167
K4831_15905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K4831_15915	COG1217	gtp-binding protein TYPA
K4831_15925	COG0339	signal peptide processing
K4831_15945	COG0137	argininosuccinate synthase activity
K4831_15950	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_15960	COG1280	lysine exporter protein (LysE YggA)
K4831_15970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K4831_15985	COG2154	pterin-4-alpha-carbinolamine dehydratase
K4831_15990	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
K4831_16000	COG1136	(ABC) transporter
K4831_16005	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K4831_16010	COG0670	Belongs to the BI1 family
K4831_16030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K4831_16035	COG4133	protoheme IX ABC transporter activity
K4831_16040	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K4831_16045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K4831_16065	COG2917	probably involved in intracellular septation
K4831_16070	COG0552	protein localization to endoplasmic reticulum
K4831_16075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K4831_16080	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K4831_16095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K4831_16100	COG0287	Prephenate dehydrogenase
K4831_16100	COG1605	Chorismate mutase
K4831_16105	COG0228	four-way junction DNA binding
K4831_16110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K4831_16115	COG0336	Belongs to the RNA methyltransferase TrmD family
K4831_16125	COG0335	large ribosomal subunit rRNA binding
K4831_16140	COG2372	response to copper ion
K4831_16145	COG1276	copper resistance
K4831_16155	COG0765	amino acid transport
K4831_16170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K4831_16185	COG0745	RESPONSE REGULATOR receiver
K4831_16205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K4831_16210	COG1674	ftsk spoiiie
K4831_16215	COG0004	ammonium transporteR
K4831_16220	COG0347	Belongs to the P(II) protein family
K4831_16225	COG1946	Acyl-CoA thioesterase
K4831_16230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K4831_16235	COG2835	tetraacyldisaccharide 4'-kinase activity
K4831_16240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K4831_16245	COG3118	belongs to the thioredoxin family
K4831_16265	COG2017	converts alpha-aldose to the beta-anomer
K4831_16280	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K4831_16285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K4831_16295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K4831_16305	COG0488	(ABC) transporter
K4831_16335	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
K4831_16365	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K4831_16370	COG0799	negative regulation of ribosome biogenesis
K4831_16375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K4831_16380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K4831_16385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K4831_16390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K4831_16410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K4831_16415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K4831_16435	COG0138	bifunctional purine biosynthesis protein purh
K4831_16445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K4831_16445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K4831_16450	COG0501	Belongs to the peptidase M48B family
K4831_16465	COG0793	Belongs to the peptidase S41A family
K4831_16475	COG0494	nUDIX hydrolase
K4831_16480	COG1192	Involved in chromosome partitioning
K4831_16505	COG2201	protein-glutamate methylesterase activity
K4831_16510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K4831_16515	COG0835	chemotaxis
K4831_16520	COG0840	transmembrane signaling receptor activity
K4831_16525	COG3290	protein histidine kinase activity
K4831_16525	COG0840	transmembrane signaling receptor activity
K4831_16530	COG0840	transmembrane signaling receptor activity
K4831_16535	COG0835	chemotaxis
K4831_16540	COG0643	Histidine kinase
K4831_16540	COG2198	Histidine kinase
K4831_16545	COG0745	RESPONSE REGULATOR receiver
K4831_16570	COG1522	sequence-specific DNA binding
K4831_16585	COG4221	oxidoreductase activity
K4831_16600	COG0738	Major facilitator superfamily
K4831_16605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K4831_16610	COG2885	chlorophyll binding
K4831_16620	COG0142	geranyltranstransferase activity
K4831_16625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K4831_16635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K4831_16640	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
K4831_16645	COG0183	Belongs to the thiolase family
K4831_16680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K4831_16710	COG0066	3-isopropylmalate dehydratase activity
K4831_16715	COG0473	3-isopropylmalate dehydrogenase activity
K4831_16720	COG0671	phosphoesterase, PA-phosphatase related
K4831_16730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K4831_16740	COG2010	Cytochrome c
K4831_16745	COG0288	reversible hydration of carbon dioxide
K4831_16750	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K4831_16755	COG2902	Dehydrogenase
K4831_16770	COG3459	Glycosyltransferase 36 associated
K4831_16775	COG1473	amidohydrolase
K4831_16790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K4831_16800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K4831_16810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K4831_16815	COG0495	leucyl-tRNA aminoacylation
K4831_16840	COG0357	Ribosomal RNA small subunit methyltransferase G
K4831_16845	COG0445	tRNA wobble uridine modification
K4831_16850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K4831_16855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K4831_16860	COG1981	membrane
K4831_16865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K4831_16870	COG1414	Transcriptional regulator
K4831_16875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K4831_16880	COG0392	lysyltransferase activity
K4831_16905	COG3257	ureidoglycine aminohydrolase activity
K4831_16925	COG1522	sequence-specific DNA binding
K4831_16940	COG4215	(ABC) transporter
K4831_16950	COG2040	homocysteine
K4831_16955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K4831_16965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K4831_16970	COG1473	amidohydrolase
K4831_17005	COG1063	alcohol dehydrogenase
K4831_17010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K4831_17015	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_17020	COG3265	gluconokinase activity
K4831_17025	COG2084	Dehydrogenase
K4831_17035	COG1609	Transcriptional regulator
K4831_17050	COG1129	ABC transporter
K4831_17070	COG1879	ABC-type sugar transport system periplasmic component
K4831_17075	COG1129	ABC transporter
K4831_17080	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_17085	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_17090	COG2186	Transcriptional regulator
K4831_17095	COG1012	belongs to the aldehyde dehydrogenase family
K4831_17100	COG1012	belongs to the aldehyde dehydrogenase family
K4831_17110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K4831_17120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_17125	COG1116	anion transmembrane transporter activity
K4831_17145	COG0778	Nitroreductase
K4831_17155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K4831_17160	COG0659	secondary active sulfate transmembrane transporter activity
K4831_17165	COG0589	response to stress
K4831_17225	COG0179	Fumarylacetoacetate (FAA) hydrolase
K4831_17240	COG1802	Transcriptional regulator
K4831_17245	COG0747	negative chemotaxis
K4831_17250	COG2723	6-phospho-beta-galactosidase activity
K4831_17255	COG0601	transmembrane transport
K4831_17265	COG3964	amidohydrolase
K4831_17280	COG1921	L-seryl-tRNASec selenium transferase activity
K4831_17285	COG3706	GGDEF domain
K4831_17285	COG2203	Gaf domain
K4831_17285	COG4251	negative regulation of phosphorylation
K4831_17285	COG5001	Diguanylate cyclase
K4831_17300	COG2080	2 iron, 2 sulfur cluster binding
K4831_17305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
K4831_17310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K4831_17335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K4831_17340	COG1486	melibiose metabolic process
K4831_17345	COG4172	Belongs to the ABC transporter superfamily
K4831_17350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_17355	COG0601	transmembrane transport
K4831_17360	COG0747	negative chemotaxis
K4831_17365	COG1486	melibiose metabolic process
K4831_17370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K4831_17370	COG2207	Transcriptional regulator
K4831_17400	COG1063	alcohol dehydrogenase
K4831_17405	COG4948	Mandelate Racemase Muconate Lactonizing
K4831_17425	COG4214	carbohydrate transport
K4831_17430	COG1129	ABC transporter
K4831_17445	COG1175	transmembrane transport
K4831_17450	COG0395	ABC-type sugar transport system, permease component
K4831_17470	COG1609	Transcriptional regulator
K4831_17485	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_17500	COG0840	transmembrane signaling receptor activity
K4831_17500	COG2972	Histidine kinase
K4831_17525	COG0667	Aldo Keto reductase
K4831_17540	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_17550	COG4213	ABC transporter substrate-binding protein
K4831_17565	COG1129	ABC transporter
K4831_17570	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_17575	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_17580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_17595	COG0765	amino acid transport
K4831_17600	COG1126	abc transporter atp-binding protein
K4831_17605	COG2079	MmgE PrpD family protein
K4831_17610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_17625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_17635	COG4172	Belongs to the ABC transporter superfamily
K4831_17640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_17665	COG2197	response regulator
K4831_17670	COG5002	protein histidine kinase activity
K4831_17670	COG3850	Histidine kinase
K4831_17675	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K4831_17685	COG2731	YhcH YjgK YiaL family protein
K4831_17690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K4831_17695	COG2271	Major facilitator Superfamily
K4831_17700	COG1609	Transcriptional regulator
K4831_17705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_17710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_17715	COG1473	amidohydrolase
K4831_17730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K4831_17740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_17760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K4831_17780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K4831_17790	COG1960	acyl-CoA dehydrogenase activity
K4831_17800	COG1309	transcriptional regulator
K4831_17830	COG2207	Transcriptional regulator
K4831_17840	COG0235	Class ii aldolase
K4831_17860	COG0300	oxidoreductase activity
K4831_17890	COG1595	DNA-templated transcription, initiation
K4831_17900	COG2824	Alkylphosphonate utilization operon protein PhnA
K4831_17925	COG3833	ABC-type maltose transport systems, permease component
K4831_17930	COG3842	ATPase activity
K4831_17935	COG0584	glycerophosphoryl diester phosphodiesterase
K4831_17975	COG1320	monovalent cation:proton antiporter activity
K4831_17980	COG2212	antiporter activity
K4831_17985	COG1863	multisubunit Na H antiporter MnhE subunit
K4831_17990	COG0651	ATP synthesis coupled electron transport
K4831_17995	COG1006	Multisubunit Na H antiporter MnhC subunit
K4831_18000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K4831_18000	COG2111	Na H antiporter
K4831_18020	COG3845	ABC transporter
K4831_18025	COG4603	Belongs to the binding-protein-dependent transport system permease family
K4831_18030	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_18035	COG0402	S-adenosylhomocysteine deaminase activity
K4831_18040	COG0402	S-adenosylhomocysteine deaminase activity
K4831_18055	COG2072	flavoprotein involved in K transport
K4831_18060	COG1177	transmembrane transport
K4831_18065	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_18070	COG3842	ATPase activity
K4831_18075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K4831_18080	COG0583	DNA-binding transcription factor activity
K4831_18105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_18110	COG0444	Belongs to the ABC transporter superfamily
K4831_18140	COG0601	transmembrane transport
K4831_18145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_18165	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_18170	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_18175	COG1846	Transcriptional regulator
K4831_18205	COG0625	glutathione transferase activity
K4831_18225	COG2133	pyrroloquinoline quinone binding
K4831_18235	COG0438	transferase activity, transferring glycosyl groups
K4831_18250	COG0753	catalase activity
K4831_18255	COG0306	phosphate transporter
K4831_18265	COG3842	ATPase activity
K4831_18270	COG1175	transmembrane transport
K4831_18275	COG0395	ABC-type sugar transport system, permease component
K4831_18300	COG3684	Belongs to the aldolase LacD family
K4831_18305	COG2390	Transcriptional regulator
K4831_18325	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_18330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K4831_18335	COG0626	cystathionine gamma-synthase activity
K4831_18340	COG1725	Transcriptional regulator
K4831_18345	COG0747	negative chemotaxis
K4831_18350	COG0601	transmembrane transport
K4831_18355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_18360	COG0444	Belongs to the ABC transporter superfamily
K4831_18365	COG4608	Belongs to the ABC transporter superfamily
K4831_18370	COG0006	proline dipeptidase activity
K4831_18380	COG0747	negative chemotaxis
K4831_18390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_18395	COG0405	Gamma-glutamyltransferase
K4831_18405	COG0754	glutathionylspermidine amidase activity
K4831_18415	COG3766	membrane
K4831_18425	COG3789	protein conserved in bacteria
K4831_18440	COG0318	PFAM AMP-dependent synthetase and ligase
K4831_18450	COG1802	Transcriptional regulator
K4831_18460	COG0601	transmembrane transport
K4831_18465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_18490	COG0747	negative chemotaxis
K4831_18500	COG2205	protein histidine kinase activity
K4831_18505	COG2197	response regulator
K4831_18510	COG4585	Histidine kinase
K4831_18525	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K4831_18530	COG4208	sulfate ABC transporter
K4831_18535	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K4831_18540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K4831_18545	COG1609	Transcriptional regulator
K4831_18550	COG0673	inositol 2-dehydrogenase activity
K4831_18560	COG1653	transport
K4831_18565	COG1175	transmembrane transport
K4831_18570	COG0395	ABC-type sugar transport system, permease component
K4831_18575	COG3842	ATPase activity
K4831_18585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K4831_18600	COG0583	DNA-binding transcription factor activity
K4831_18605	COG0402	S-adenosylhomocysteine deaminase activity
K4831_18610	COG3250	beta-galactosidase activity
K4831_18615	COG1940	carbohydrate kinase activity
K4831_18620	COG2116	formate transmembrane transporter activity
K4831_18625	COG0402	S-adenosylhomocysteine deaminase activity
K4831_18635	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_18640	COG4603	Belongs to the binding-protein-dependent transport system permease family
K4831_18645	COG3845	ABC transporter
K4831_18670	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K4831_18690	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K4831_18695	COG0402	S-adenosylhomocysteine deaminase activity
K4831_18705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K4831_18710	COG2080	2 iron, 2 sulfur cluster binding
K4831_18715	COG1012	belongs to the aldehyde dehydrogenase family
K4831_18730	COG2186	Transcriptional regulator
K4831_18735	COG1304	FMN binding
K4831_18745	COG0179	Fumarylacetoacetate (FAA) hydrolase
K4831_18790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K4831_18795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K4831_18800	COG1126	abc transporter atp-binding protein
K4831_18805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K4831_18810	COG0765	amino acid transport
K4831_18815	COG0765	amino acid transport
K4831_18820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K4831_18830	COG1764	response to oxidative stress
K4831_18845	COG1116	anion transmembrane transporter activity
K4831_18850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_18855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K4831_18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K4831_18865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_18870	COG1959	2 iron, 2 sulfur cluster binding
K4831_18895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K4831_18950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K4831_18960	COG1116	anion transmembrane transporter activity
K4831_18970	COG4191	Histidine kinase
K4831_18975	COG4566	intracellular signal transduction
K4831_18985	COG3842	ATPase activity
K4831_18990	COG0395	ABC-type sugar transport system, permease component
K4831_18995	COG1175	transmembrane transport
K4831_19030	COG1940	carbohydrate kinase activity
K4831_19035	COG0747	negative chemotaxis
K4831_19040	COG0601	transmembrane transport
K4831_19045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_19055	COG4608	Belongs to the ABC transporter superfamily
K4831_19065	COG2205	protein histidine kinase activity
K4831_19075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K4831_19085	COG2076	Multidrug Resistance protein
K4831_19105	COG2076	Multidrug Resistance protein
K4831_19120	COG1215	transferase activity, transferring glycosyl groups
K4831_19135	COG2202	Pas domain
K4831_19135	COG3920	Histidine kinase
K4831_19145	COG0784	Response regulator, receiver
K4831_19155	COG1162	GTPase activity
K4831_19160	COG4191	Histidine kinase
K4831_19160	COG0784	Response regulator, receiver
K4831_19165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K4831_19180	COG1126	abc transporter atp-binding protein
K4831_19185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K4831_19190	COG1609	Transcriptional regulator
K4831_19195	COG2972	Histidine kinase
K4831_19195	COG0840	transmembrane signaling receptor activity
K4831_19200	COG0835	chemotaxis
K4831_19210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K4831_19225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K4831_19235	COG0789	Transcriptional regulator
K4831_19240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K4831_19245	COG0366	Alpha amylase catalytic
K4831_19250	COG0366	Alpha amylase catalytic
K4831_19255	COG1640	4-alpha-glucanotransferase
K4831_19260	COG1278	Cold shock
K4831_19265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K4831_19275	COG0673	inositol 2-dehydrogenase activity
K4831_19285	COG1802	Transcriptional regulator
K4831_19290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K4831_19300	COG0673	inositol 2-dehydrogenase activity
K4831_19310	COG1175	transmembrane transport
K4831_19315	COG0395	ABC-type sugar transport system, permease component
K4831_19325	COG0673	inositol 2-dehydrogenase activity
K4831_19335	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
K4831_19345	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_19355	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
K4831_19360	COG3920	Histidine kinase
K4831_19375	COG3685	Protein conserved in bacteria
K4831_19405	COG5001	Diguanylate cyclase
K4831_19410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K4831_19430	COG1132	(ABC) transporter
K4831_19435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K4831_19435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K4831_19450	COG3842	ATPase activity
K4831_19455	COG3833	ABC-type maltose transport systems, permease component
K4831_19470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K4831_19500	COG0604	alcohol dehydrogenase
K4831_19500	COG3321	synthase
K4831_19520	COG1960	acyl-CoA dehydrogenase activity
K4831_19530	COG4608	Belongs to the ABC transporter superfamily
K4831_19545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_19550	COG0747	negative chemotaxis
K4831_19570	COG0583	DNA-binding transcription factor activity
K4831_19575	COG0747	negative chemotaxis
K4831_19585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_19600	COG0154	amidase activity
K4831_19615	COG1335	isochorismatase
K4831_19620	COG3845	ABC transporter
K4831_19635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K4831_19640	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_19660	COG4172	Belongs to the ABC transporter superfamily
K4831_19665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_19670	COG0601	transmembrane transport
K4831_19700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_19705	COG1012	belongs to the aldehyde dehydrogenase family
K4831_19715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K4831_19720	COG1309	transcriptional regulator
K4831_19735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K4831_19750	COG4770	biotin carboxylase activity
K4831_19765	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K4831_19765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K4831_19790	COG0179	Fumarylacetoacetate (FAA) hydrolase
K4831_19795	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_19800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K4831_19800	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
K4831_19805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K4831_19815	COG4172	Belongs to the ABC transporter superfamily
K4831_19820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_19825	COG0601	transmembrane transport
K4831_19830	COG0747	negative chemotaxis
K4831_19835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K4831_19840	COG2186	Transcriptional regulator
K4831_19850	COG0640	Transcriptional regulator
K4831_19860	COG3842	ATPase activity
K4831_19865	COG1175	transmembrane transport
K4831_19870	COG0395	ABC-type sugar transport system, permease component
K4831_19880	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K4831_19890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_19895	COG1012	belongs to the aldehyde dehydrogenase family
K4831_19900	COG2084	Dehydrogenase
K4831_19910	COG3386	PFAM SMP-30 Gluconolaconase
K4831_19920	COG2771	luxR family
K4831_19930	COG0626	cystathionine gamma-synthase activity
K4831_19945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K4831_19980	COG1175	transmembrane transport
K4831_19985	COG0395	ABC-type sugar transport system, permease component
K4831_20010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K4831_20010	COG0446	pyridine nucleotide-disulphide oxidoreductase
K4831_20015	COG4311	Sarcosine oxidase, delta subunit
K4831_20020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_20025	COG4977	sequence-specific DNA binding
K4831_20035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K4831_20040	COG2218	PFAM glutamate synthase alpha subunit domain protein
K4831_20045	COG0069	glutamate synthase activity
K4831_20060	COG1304	FMN binding
K4831_20075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K4831_20090	COG1175	transmembrane transport
K4831_20095	COG0395	ABC-type sugar transport system, permease component
K4831_20100	COG1609	Transcriptional regulator
K4831_20115	COG0412	Dienelactone hydrolase
K4831_20125	COG0583	DNA-binding transcription factor activity
K4831_20135	COG0583	DNA-binding transcription factor activity
K4831_20160	COG0306	phosphate transporter
K4831_20175	COG0277	FAD linked oxidase domain protein
K4831_20180	COG0277	FAD linked oxidase domain protein
K4831_20185	COG0247	lactate metabolic process
K4831_20195	COG0625	glutathione transferase activity
K4831_20205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K4831_20210	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
K4831_20235	COG0124	histidyl-tRNA synthetase
K4831_20265	COG2818	Glycosylase
K4831_20270	COG1376	ErfK ybiS ycfS ynhG family protein
K4831_20270	COG1388	LysM domain
K4831_20275	COG1376	ErfK ybiS ycfS ynhG family protein
K4831_20280	COG2909	trisaccharide binding
K4831_20285	COG2977	Belongs to the P-Pant transferase superfamily
K4831_20290	COG2137	regulation of response to DNA damage stimulus
K4831_20295	COG2130	NADP-dependent
K4831_20310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K4831_20325	COG0196	riboflavin kinase activity
K4831_20335	COG2059	Chromate
K4831_20340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K4831_20345	COG0459	protein refolding
K4831_20365	COG3842	ATPase activity
K4831_20375	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_20380	COG1177	transmembrane transport
K4831_20385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K4831_20390	COG0019	diaminopimelate decarboxylase activity
K4831_20400	COG4770	biotin carboxylase activity
K4831_20405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K4831_20410	COG4336	lyase activity
K4831_20415	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K4831_20420	COG1914	H( )-stimulated, divalent metal cation uptake system
K4831_20425	COG1802	Transcriptional regulator
K4831_20430	COG1522	sequence-specific DNA binding
K4831_20435	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K4831_20460	COG0583	DNA-binding transcription factor activity
K4831_20465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K4831_20470	COG0511	ligase activity, forming carbon-carbon bonds
K4831_20475	COG0439	Biotin carboxylase
K4831_20485	COG1984	allophanate hydrolase subunit 2
K4831_20495	COG3842	ATPase activity
K4831_20500	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_20510	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_20515	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_20525	COG3842	ATPase activity
K4831_20530	COG0726	polysaccharide deacetylase
K4831_20540	COG0523	cobalamin synthesis protein
K4831_20555	COG1522	sequence-specific DNA binding
K4831_20565	COG0659	secondary active sulfate transmembrane transporter activity
K4831_20575	COG0243	molybdopterin cofactor binding
K4831_20585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K4831_20590	COG1116	anion transmembrane transporter activity
K4831_20595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_20600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K4831_20605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K4831_20610	COG3707	response regulator
K4831_20630	COG0583	DNA-binding transcription factor activity
K4831_20635	COG1960	acyl-CoA dehydrogenase activity
K4831_20640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K4831_20655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K4831_20670	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K4831_20685	COG2022	thiamine diphosphate biosynthetic process
K4831_20730	COG2963	transposase activity
K4831_20740	COG2963	transposase activity
K4831_20790	COG2070	2-Nitropropane dioxygenase
K4831_20790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K4831_20795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K4831_20800	COG0367	asparagine synthase
K4831_20805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K4831_20805	COG0300	oxidoreductase activity
K4831_20805	COG3321	synthase
K4831_20805	COG4221	oxidoreductase activity
K4831_20810	COG3321	synthase
K4831_20810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K4831_20810	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_20810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K4831_20810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K4831_20935	COG0640	Transcriptional regulator
K4831_20940	COG0798	PFAM Bile acid sodium symporter
K4831_20945	COG1393	Belongs to the ArsC family
K4831_20970	COG0745	RESPONSE REGULATOR receiver
K4831_20975	COG2205	protein histidine kinase activity
K4831_20980	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K4831_20990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K4831_21015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_21020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K4831_21025	COG1522	sequence-specific DNA binding
K4831_21040	COG2267	carboxylic ester hydrolase activity
K4831_21050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_21055	COG1012	belongs to the aldehyde dehydrogenase family
K4831_21070	COG1177	transmembrane transport
K4831_21075	COG3842	ATPase activity
K4831_21080	COG1012	belongs to the aldehyde dehydrogenase family
K4831_21090	COG4154	Belongs to the RbsD FucU family
K4831_21100	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_21105	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_21110	COG1129	ABC transporter
K4831_21130	COG2721	sulfolactate sulfo-lyase activity
K4831_21140	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_21155	COG0745	RESPONSE REGULATOR receiver
K4831_21190	COG0183	Belongs to the thiolase family
K4831_21195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K4831_21205	COG1414	Transcriptional regulator
K4831_21220	COG0583	DNA-binding transcription factor activity
K4831_21225	COG2267	carboxylic ester hydrolase activity
K4831_21230	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K4831_21235	COG3485	protocatechuate 3,4-dioxygenase
K4831_21240	COG3485	protocatechuate 3,4-dioxygenase
K4831_21245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K4831_21250	COG0604	alcohol dehydrogenase
K4831_21255	COG1674	ftsk spoiiie
K4831_21260	COG3842	ATPase activity
K4831_21275	COG0668	transmembrane transport
K4831_21290	COG5265	(ABC) transporter
K4831_21295	COG2205	protein histidine kinase activity
K4831_21300	COG0745	RESPONSE REGULATOR receiver
K4831_21375	COG0582	viral genome integration into host DNA
K4831_21385	COG3346	SURF1 family
K4831_21390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K4831_21395	COG1845	cytochrome c oxidase, subunit III
K4831_21400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K4831_21410	COG1595	DNA-templated transcription, initiation
K4831_21420	COG0670	Belongs to the BI1 family
K4831_21440	COG1301	dicarboxylic acid transport
K4831_21445	COG4191	Histidine kinase
K4831_21450	COG2204	response regulator
K4831_21455	COG1309	transcriptional regulator
K4831_21475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K4831_21480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K4831_21485	COG2188	Transcriptional regulator
K4831_21500	COG0395	ABC-type sugar transport system, permease component
K4831_21510	COG3842	ATPase activity
K4831_21535	COG0837	glucose binding
K4831_21535	COG1737	Transcriptional regulator
K4831_21540	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_21555	COG2814	Major facilitator Superfamily
K4831_21560	COG3142	Participates in the control of copper homeostasis
K4831_21580	COG0642	Histidine kinase
K4831_21600	COG4952	isomerase
K4831_21605	COG3347	Dehydrogenase
K4831_21605	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_21620	COG1129	ABC transporter
K4831_21625	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_21630	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_21635	COG3254	rhamnose metabolic process
K4831_21645	COG0179	Fumarylacetoacetate (FAA) hydrolase
K4831_21665	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_21675	COG3842	ATPase activity
K4831_21695	COG2094	Belongs to the DNA glycosylase MPG family
K4831_21700	COG4181	ATPase activity
K4831_21705	COG0577	efflux transmembrane transporter activity
K4831_21715	COG4303	Ethanolamine ammonia lyase large subunit
K4831_21725	COG1192	Involved in chromosome partitioning
K4831_21730	COG1475	DNA binding
K4831_21735	COG1475	DNA binding
K4831_21740	COG0640	Transcriptional regulator
K4831_21750	COG1192	Involved in chromosome partitioning
K4831_21755	COG1475	DNA binding
K4831_21760	COG0640	Transcriptional regulator
K4831_21765	COG4691	Plasmid stability protein
K4831_21770	COG1487	ribonuclease activity
K4831_21805	COG1136	(ABC) transporter
K4831_21815	COG2207	Transcriptional regulator
K4831_21815	COG1917	Cupin 2, conserved barrel domain protein
K4831_21845	COG2423	ornithine cyclodeaminase activity
K4831_21855	COG4608	Belongs to the ABC transporter superfamily
K4831_21870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_21875	COG0747	negative chemotaxis
K4831_21915	COG0154	amidase activity
K4831_21925	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_21965	COG0583	DNA-binding transcription factor activity
K4831_21975	COG1858	cytochrome C peroxidase
K4831_22000	COG1192	Involved in chromosome partitioning
K4831_22055	COG3842	ATPase activity
K4831_22060	COG3842	ATPase activity
K4831_22070	COG0395	ABC-type sugar transport system, permease component
K4831_22075	COG1175	transmembrane transport
K4831_22085	COG1609	Transcriptional regulator
K4831_22145	COG0739	heme binding
K4831_22145	COG0741	lytic transglycosylase activity
K4831_22145	COG1196	nuclear chromosome segregation
K4831_22165	COG3831	ATPase activity
K4831_22170	COG1192	Involved in chromosome partitioning
K4831_22175	COG1475	DNA binding
K4831_22180	COG0640	Transcriptional regulator
K4831_22190	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K4831_22245	COG1196	nuclear chromosome segregation
K4831_22250	COG2175	clavaminate synthase activity
K4831_22290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K4831_22305	COG0587	DNA-directed DNA polymerase activity
K4831_22340	COG1475	DNA binding
K4831_22380	COG5489	Protein of unknown function (DUF736)
K4831_22485	COG0483	inositol monophosphate 1-phosphatase activity
K4831_22490	COG0584	glycerophosphoryl diester phosphodiesterase
K4831_22500	COG1177	transmembrane transport
K4831_22510	COG3842	ATPase activity
K4831_22515	COG1940	carbohydrate kinase activity
K4831_22535	COG3842	ATPase activity
K4831_22540	COG4149	molybdate abc transporter
K4831_22545	COG1177	transmembrane transport
K4831_22555	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_22560	COG1177	transmembrane transport
K4831_22565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K4831_22570	COG3842	ATPase activity
K4831_22580	COG0747	negative chemotaxis
K4831_22590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_22610	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_22620	COG1840	ABC-type Fe3 transport system, periplasmic component
K4831_22645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_22650	COG4172	Belongs to the ABC transporter superfamily
K4831_22660	COG1064	alcohol dehydrogenase
K4831_22690	COG4149	molybdate abc transporter
K4831_22695	COG1177	transmembrane transport
K4831_22700	COG3842	ATPase activity
K4831_22705	COG1840	ABC-type Fe3 transport system, periplasmic component
K4831_22715	COG4172	Belongs to the ABC transporter superfamily
K4831_22720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_22725	COG0601	transmembrane transport
K4831_22730	COG4166	transmembrane transport
K4831_22785	COG3701	Conjugal transfer protein
K4831_22790	COG3846	protein secretion by the type IV secretion system
K4831_22800	COG5314	conjugation
K4831_22805	COG3451	type IV secretory pathway VirB4
K4831_22820	COG4962	Type ii secretion system protein e
K4831_22830	COG1192	Involved in chromosome partitioning
K4831_22835	COG0640	Transcriptional regulator
K4831_22840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K4831_22845	COG3177	Filamentation induced by cAMP protein fic
K4831_22860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K4831_22915	COG0583	DNA-binding transcription factor activity
K4831_23000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K4831_23015	COG1132	(ABC) transporter
K4831_23020	COG4172	Belongs to the ABC transporter superfamily
K4831_23025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_23035	COG0747	negative chemotaxis
K4831_23045	COG1082	Xylose isomerase domain protein TIM barrel
K4831_23115	COG1475	DNA binding
K4831_23155	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
K4831_23160	COG5489	Protein of unknown function (DUF736)
K4831_23235	COG4172	Belongs to the ABC transporter superfamily
K4831_23240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_23260	COG2072	flavoprotein involved in K transport
K4831_23265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K4831_23335	COG0584	glycerophosphoryl diester phosphodiesterase
K4831_23360	COG0444	Belongs to the ABC transporter superfamily
K4831_23375	COG0747	negative chemotaxis
K4831_23395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_23400	COG0601	transmembrane transport
K4831_23415	COG0444	Belongs to the ABC transporter superfamily
K4831_23420	COG0747	negative chemotaxis
K4831_23430	COG2390	Transcriptional regulator
K4831_23445	COG4172	Belongs to the ABC transporter superfamily
K4831_23450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_23455	COG0601	transmembrane transport
K4831_23475	COG0010	Belongs to the arginase family
K4831_23535	COG1283	sodium-dependent phosphate transmembrane transporter activity
K4831_23540	COG0483	inositol monophosphate 1-phosphatase activity
K4831_23545	COG0584	glycerophosphoryl diester phosphodiesterase
K4831_23555	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_23560	COG1175	transmembrane transport
K4831_23565	COG3842	ATPase activity
K4831_23585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K4831_23595	COG1228	amidohydrolase
K4831_23605	COG1177	transmembrane transport
K4831_23615	COG3842	ATPase activity
K4831_23640	COG2986	histidine ammonia-lyase
K4831_23665	COG0765	amino acid transport
K4831_23680	COG2079	MmgE PrpD family protein
K4831_23685	COG0583	DNA-binding transcription factor activity
K4831_23705	COG3701	Conjugal transfer protein
K4831_23710	COG3846	protein secretion by the type IV secretion system
K4831_23720	COG5314	conjugation
K4831_23725	COG3451	type IV secretory pathway VirB4
K4831_23740	COG4962	Type ii secretion system protein e
K4831_23750	COG1192	Involved in chromosome partitioning
K4831_23755	COG1475	DNA binding
K4831_23760	COG0640	Transcriptional regulator
K4831_23780	COG3335	DDE superfamily endonuclease
K4831_23785	COG3415	Transposase
K4831_23800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K4831_23830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K4831_23835	COG2814	Major facilitator Superfamily
K4831_23845	COG0235	Class ii aldolase
K4831_23880	COG1396	sequence-specific DNA binding
K4831_23930	COG4297	protein containing double-stranded beta helix domain
K4831_24020	COG1522	sequence-specific DNA binding
K4831_24070	COG4191	Histidine kinase
K4831_24070	COG0784	Response regulator, receiver
K4831_24105	COG0784	Response regulator, receiver
K4831_24105	COG4191	Histidine kinase
K4831_24165	COG0840	transmembrane signaling receptor activity
K4831_24175	COG4251	negative regulation of phosphorylation
K4831_24185	COG3344	reverse transcriptase
K4831_24190	COG0840	transmembrane signaling receptor activity
K4831_24190	COG2972	Histidine kinase
K4831_24205	COG5002	protein histidine kinase activity
K4831_24215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K4831_24220	COG3850	Histidine kinase
K4831_24220	COG2205	protein histidine kinase activity
K4831_24220	COG4999	Histidine kinase
K4831_24220	COG3437	response regulator, receiver
K4831_24245	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K4831_24265	COG1396	sequence-specific DNA binding
K4831_24270	COG3621	Patatin-like phospholipase
K4831_24315	COG3265	gluconokinase activity
K4831_24320	COG1028	Short-chain dehydrogenase reductase Sdr
K4831_24325	COG1129	ABC transporter
K4831_24330	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_24350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K4831_24355	COG1609	Transcriptional regulator
K4831_24380	COG2195	Cleaves the N-terminal amino acid of tripeptides
K4831_24385	COG2843	Capsule synthesis protein
K4831_24395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_24400	COG0601	transmembrane transport
K4831_24405	COG4166	transmembrane transport
K4831_24420	COG3609	addiction module antidote protein, CC2985 family
K4831_24430	COG4584	PFAM Integrase catalytic
K4831_24435	COG1484	DNA-dependent DNA replication
K4831_24450	COG3177	Filamentation induced by cAMP protein fic
K4831_24565	COG0776	regulation of translation
K4831_24570	COG5489	Protein of unknown function (DUF736)
K4831_24580	COG0300	oxidoreductase activity
K4831_24595	COG1475	DNA binding
K4831_24700	COG3701	Conjugal transfer protein
K4831_24705	COG3846	protein secretion by the type IV secretion system
K4831_24715	COG5314	conjugation
K4831_24720	COG3451	type IV secretory pathway VirB4
K4831_24735	COG4962	Type ii secretion system protein e
K4831_24745	COG1192	Involved in chromosome partitioning
K4831_24750	COG1475	DNA binding
K4831_24755	COG0640	Transcriptional regulator
K4831_24760	COG2072	flavoprotein involved in K transport
K4831_24765	COG3706	GGDEF domain
K4831_24800	COG2188	Transcriptional regulator
K4831_24810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K4831_24835	COG2986	histidine ammonia-lyase
K4831_24845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K4831_24865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_24870	COG0601	transmembrane transport
K4831_24890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K4831_24905	COG4608	Belongs to the ABC transporter superfamily
K4831_24910	COG0444	Belongs to the ABC transporter superfamily
K4831_24915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_24920	COG0601	transmembrane transport
K4831_24930	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K4831_24960	COG0084	hydrolase, TatD family'
K4831_24965	COG1079	Belongs to the binding-protein-dependent transport system permease family
K4831_24970	COG4603	Belongs to the binding-protein-dependent transport system permease family
K4831_24975	COG3845	ABC transporter
K4831_24985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K4831_24990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K4831_25005	COG3842	ATPase activity
K4831_25010	COG1177	transmembrane transport
K4831_25015	COG1176	ABC-type spermidine putrescine transport system, permease component I
K4831_25045	COG1475	DNA binding
K4831_25050	COG0019	diaminopimelate decarboxylase activity
K4831_25055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K4831_25060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K4831_25065	COG4264	IucA IucC family
K4831_25070	COG2814	Major facilitator Superfamily
K4831_25105	COG2186	Transcriptional regulator
K4831_25115	COG0765	amino acid transport
K4831_25130	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K4831_25140	COG1177	transmembrane transport
K4831_25150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K4831_25160	COG1309	transcriptional regulator
K4831_25175	COG0395	ABC-type sugar transport system, permease component
K4831_25200	COG0243	molybdopterin cofactor binding
K4831_25215	COG2826	transposase and inactivated derivatives, IS30 family
K4831_25250	COG2205	protein histidine kinase activity
K4831_25255	COG0745	RESPONSE REGULATOR receiver
K4831_25295	COG1735	metal-dependent hydrolase with the TIM-barrel fold
K4831_25300	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_25315	COG1609	Transcriptional regulator
K4831_25330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K4831_25335	COG0243	molybdopterin cofactor binding
K4831_25340	COG2207	Transcriptional regulator
K4831_25340	COG0662	Cupin 2, conserved barrel domain protein
K4831_25395	COG5001	Diguanylate cyclase
K4831_25395	COG4251	negative regulation of phosphorylation
K4831_25395	COG3706	GGDEF domain
K4831_25395	COG2203	Gaf domain
K4831_25400	COG0583	DNA-binding transcription factor activity
K4831_25405	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
K4831_25445	COG1335	isochorismatase
K4831_25450	COG2309	aminopeptidase activity
K4831_25455	COG0596	Alpha beta hydrolase
K4831_25460	COG3473	Maleate cis-trans isomerase
K4831_25475	COG2080	2 iron, 2 sulfur cluster binding
K4831_25485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K4831_25500	COG2223	nitrite transmembrane transporter activity
K4831_25515	COG3842	ATPase activity
K4831_25530	COG1175	transmembrane transport
K4831_25535	COG1653	transport
K4831_25540	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K4831_25540	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K4831_25555	COG4770	biotin carboxylase activity
K4831_25570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K4831_25595	COG1960	acyl-CoA dehydrogenase activity
K4831_25600	COG0183	Belongs to the thiolase family
K4831_25610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K4831_25675	COG4977	sequence-specific DNA binding
K4831_25675	COG1917	Cupin 2, conserved barrel domain protein
K4831_25730	COG2814	Major facilitator Superfamily
K4831_25735	COG0583	DNA-binding transcription factor activity
K4831_25750	COG4977	sequence-specific DNA binding
K4831_25840	COG2963	transposase activity
K4831_25860	COG3284	Transcriptional regulator
K4831_25865	COG1063	alcohol dehydrogenase
K4831_25895	COG2181	nitrate reductase activity
K4831_25895	COG0247	lactate metabolic process
K4831_25905	COG0277	FAD linked oxidase domain protein
K4831_25940	COG2124	cytochrome p450
K4831_25955	COG0318	PFAM AMP-dependent synthetase and ligase
K4831_25965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K4831_25970	COG1024	Enoyl-CoA hydratase
K4831_25990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K4831_26010	COG1573	uracil-dna glycosylase
K4831_26040	COG1802	Transcriptional regulator
K4831_26045	COG2186	Transcriptional regulator
K4831_26050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K4831_26055	COG1012	belongs to the aldehyde dehydrogenase family
K4831_26060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K4831_26070	COG3448	diguanylate cyclase activity
K4831_26070	COG4175	Glycine betaine
K4831_26075	COG4176	ABC-type proline glycine betaine transport system permease component
K4831_26080	COG4176	ABC-type proline glycine betaine transport system permease component
K4831_26085	COG3938	Belongs to the proline racemase family
K4831_26105	COG4644	lycopene metabolic process
K4831_26125	COG1069	ribulokinase activity
K4831_26130	COG3177	Filamentation induced by cAMP protein fic
K4831_26145	COG1737	Transcriptional regulator
K4831_26150	COG1172	Belongs to the binding-protein-dependent transport system permease family
K4831_26155	COG1129	ABC transporter
K4831_26170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K4831_26180	COG0395	ABC-type sugar transport system, permease component
K4831_26185	COG1175	transmembrane transport
K4831_26195	COG3842	ATPase activity
K4831_26210	COG2186	Transcriptional regulator
K4831_26225	COG1175	transmembrane transport
K4831_26230	COG0395	ABC-type sugar transport system, permease component
K4831_26240	COG3842	ATPase activity
K4831_26260	COG0110	maltose O-acetyltransferase activity
K4831_26275	COG1175	transmembrane transport
K4831_26280	COG0395	ABC-type sugar transport system, permease component
K4831_26290	COG1940	carbohydrate kinase activity
K4831_26305	COG4172	Belongs to the ABC transporter superfamily
K4831_26310	COG0747	negative chemotaxis
K4831_26320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_26325	COG2362	D-Aminopeptidase
K4831_26330	COG1446	asparaginase
K4831_26345	COG0840	transmembrane signaling receptor activity
K4831_26355	COG3547	Transposase (IS116 IS110 IS902 family)
K4831_26370	COG4372	Transposase
K4831_26380	COG2963	transposase activity
K4831_26390	COG1959	2 iron, 2 sulfur cluster binding
K4831_26395	COG0534	Mate efflux family protein
K4831_26415	COG0318	PFAM AMP-dependent synthetase and ligase
K4831_26425	COG2226	methyltransferase
K4831_26475	COG4774	siderophore transport
K4831_26475	COG1629	transport
K4831_26480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K4831_26485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K4831_26495	COG1120	ATPase activity
K4831_26570	COG0601	transmembrane transport
K4831_26575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K4831_26580	COG4608	Belongs to the ABC transporter superfamily
K4831_26585	COG1349	DNA-binding transcription factor activity
K4831_26590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K4831_26605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K4831_26615	COG1802	Transcriptional regulator
K4831_26625	COG0765	amino acid transport
K4831_26630	COG0765	amino acid transport
K4831_26655	COG1192	Involved in chromosome partitioning
K4831_26660	COG1475	DNA binding