locus-tag	class	description
Avi_0001	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Avi_0002	COG0424	maF-like protein
Avi_0004	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avi_0005	COG0237	dephospho-CoA kinase activity
Avi_0006	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Avi_0007	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Avi_0010	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Avi_0013	COG0187	DNA topoisomerase II activity
Avi_0019	COG0135	phosphoribosylanthranilate isomerase activity
Avi_0020	COG0133	tryptophan synthase activity
Avi_0021	COG0159	tryptophan synthase activity
Avi_0022	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Avi_0024	COG0285	dihydrofolate synthase activity
Avi_0031	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Avi_0032	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Avi_0033	COG0131	Imidazoleglycerol-phosphate dehydratase
Avi_0035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Avi_0036	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Avi_0037	COG0107	imidazoleglycerol-phosphate synthase activity
Avi_0038	COG0140	phosphoribosyl-ATP diphosphatase activity
Avi_0039	COG1072	(Pantothenic acid kinase))
Avi_0042	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Avi_0044	COG0745	RESPONSE REGULATOR receiver
Avi_0045	COG0642	Histidine kinase
Avi_0047	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Avi_0047	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Avi_0048	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Avi_0049	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Avi_0050	COG2205	protein histidine kinase activity
Avi_0051	COG3178	'Phosphotransferase
Avi_0053	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Avi_0055	COG2887	Belongs to the helicase family. UvrD subfamily
Avi_0056	COG1074	ATP-dependent DNA helicase activity
Avi_0057	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Avi_0063	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Avi_0067	COG1643	Atp-dependent helicase
Avi_0068	COG2423	ornithine cyclodeaminase activity
Avi_0070	COG2814	Major facilitator Superfamily
Avi_0071	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_0072	COG1609	Transcriptional regulator
Avi_0074	COG0673	inositol 2-dehydrogenase activity
Avi_0076	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avi_0077	COG3962	Belongs to the TPP enzyme family
Avi_0080	COG3718	enzyme involved in inositol metabolism
Avi_0085	COG4221	oxidoreductase activity
Avi_0086	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Avi_0089	COG1595	DNA-templated transcription, initiation
Avi_0090	COG3806	Anti-sigma factor
Avi_0096	COG3842	ATPase activity
Avi_0098	COG0395	ABC-type sugar transport system, permease component
Avi_0102	COG3474	cytochrome
Avi_0103	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Avi_0105	COG0077	Prephenate dehydratase
Avi_0105	COG1605	Chorismate mutase
Avi_0108	COG2816	NAD+ diphosphatase activity
Avi_0110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Avi_0111	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Avi_0113	COG3422	double-strand break repair
Avi_0116	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Avi_0118	COG0481	GTPase activity
Avi_0126	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Avi_0127	COG1607	acyl-coa hydrolase
Avi_0134	COG1393	Belongs to the ArsC family
Avi_0136	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Avi_0137	COG2309	aminopeptidase activity
Avi_0142	COG1278	Cold shock
Avi_0143	COG1570	exodeoxyribonuclease VII activity
Avi_0153	COG0667	Aldo Keto reductase
Avi_0156	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Avi_0157	COG2951	lytic endotransglycosylase activity
Avi_0163	COG2814	Major facilitator Superfamily
Avi_0164	COG0779	Required for maturation of 30S ribosomal subunits
Avi_0166	COG0195	Participates in both transcription termination and antitermination
Avi_0166	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Avi_0169	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Avi_0170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Avi_0171	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Avi_0173	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Avi_0175	COG1185	polyribonucleotide nucleotidyltransferase activity
Avi_0178	COG2813	Specifically methylates the guanine in position
Avi_0179	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Avi_0181	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Avi_0184	COG2860	membrane
Avi_0190	COG0477	Major facilitator Superfamily
Avi_0193	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Avi_0194	COG0539	negative regulation of cytoplasmic translation
Avi_0200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Avi_0202	COG0745	RESPONSE REGULATOR receiver
Avi_0203	COG2205	protein histidine kinase activity
Avi_0205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Avi_0206	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Avi_0208	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Avi_0209	COG0072	phenylalanine-tRNA ligase activity
Avi_0209	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Avi_0217	COG4964	Belongs to the GSP D family
Avi_0229	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Avi_0230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Avi_0231	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Avi_0233	COG1280	lysine exporter protein (LysE YggA)
Avi_0235	COG0588	phosphoglycerate mutase activity
Avi_0237	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Avi_0238	COG1132	(ABC) transporter
Avi_0239	COG0837	glucose binding
Avi_0240	COG1803	Methylglyoxal synthase
Avi_0241	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Avi_0244	COG4166	transmembrane transport
Avi_0245	COG4174	ABC transporter (Permease)
Avi_0246	COG4239	(ABC) transporter, permease
Avi_0247	COG4172	Belongs to the ABC transporter superfamily
Avi_0248	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Avi_0250	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Avi_0264	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Avi_0265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Avi_0266	COG2188	Transcriptional regulator
Avi_0267	COG3624	Phosphonate C-P lyase system protein PhnG
Avi_0269	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
Avi_0270	COG3626	phosphonate metabolism
Avi_0273	COG3627	carbon phosphorus lyase activity
Avi_0274	COG4107	phosphonate C-P lyase system protein PhnK
Avi_0275	COG4778	phosphonate C-P lyase system protein PhnL
Avi_0278	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Avi_0280	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Avi_0284	COG3639	organic phosphonate transmembrane transporter activity
Avi_0286	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Avi_0287	COG3454	Phosphonate metabolism
Avi_0288	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Avi_0292	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Avi_0293	COG2353	YceI-like domain
Avi_0295	COG2353	YceI-like domain
Avi_0297	COG0791	NLP P60 protein
Avi_0299	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Avi_0299	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Avi_0301	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Avi_0303	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Avi_0306	COG0443	Heat shock 70 kDa protein
Avi_0308	COG0484	heat shock protein binding
Avi_0309	COG2900	Belongs to the SlyX family
Avi_0311	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Avi_0314	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avi_0316	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avi_0317	COG5001	Diguanylate cyclase
Avi_0319	COG3002	Belongs to the UPF0753 family
Avi_0327	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Avi_0327	COG0519	Catalyzes the synthesis of GMP from XMP
Avi_0330	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Avi_0336	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Avi_0336	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Avi_0337	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Avi_0340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Avi_0342	COG1968	undecaprenyl-diphosphatase activity
Avi_0347	COG0284	orotidine-5'-phosphate decarboxylase activity
Avi_0349	COG3963	phosphatidate phosphatase activity
Avi_0351	COG0592	DNA-directed DNA polymerase activity
Avi_0352	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Avi_0353	COG0792	nuclease activity
Avi_0356	COG1175	transmembrane transport
Avi_0357	COG0395	ABC-type sugar transport system, permease component
Avi_0359	COG3842	ATPase activity
Avi_0361	COG0189	ligase activity
Avi_0363	COG0606	chelatase, subunit chli
Avi_0366	COG1280	lysine exporter protein (LysE YggA)
Avi_0368	COG0756	dUTP diphosphatase activity
Avi_0369	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Avi_0370	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Avi_0371	COG1877	trehalose-phosphatase activity
Avi_0377	COG1741	Belongs to the pirin family
Avi_0380	COG0583	DNA-binding transcription factor activity
Avi_0383	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Avi_0384	COG3920	Histidine kinase
Avi_0385	COG3437	response regulator, receiver
Avi_0386	COG2205	protein histidine kinase activity
Avi_0386	COG2198	Histidine kinase
Avi_0386	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_0386	COG0784	Response regulator, receiver
Avi_0387	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Avi_0388	COG2226	methyltransferase
Avi_0389	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Avi_0390	COG0268	Binds directly to 16S ribosomal RNA
Avi_0391	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Avi_0392	COG0697	spore germination
Avi_0393	COG2226	methyltransferase
Avi_0394	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Avi_0395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Avi_0397	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Avi_0398	COG1420	regulation of RNA biosynthetic process
Avi_0399	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Avi_0401	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Avi_0402	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Avi_0405	COG1137	ATPase activity
Avi_0406	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Avi_0409	COG0776	regulation of translation
Avi_0413	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Avi_0413	COG0116	Belongs to the methyltransferase superfamily
Avi_0414	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Avi_0415	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Avi_0422	COG0583	DNA-binding transcription factor activity
Avi_0423	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Avi_0424	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Avi_0426	COG0346	lactoylglutathione lyase activity
Avi_0427	COG0180	Tryptophanyl-tRNA synthetase
Avi_0430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Avi_0432	COG1214	PFAM Peptidase M22, glycoprotease
Avi_0437	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Avi_0438	COG1702	phosphate starvation-inducible protein PhoH
Avi_0440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Avi_0441	COG4535	Mg2 and Co2 transporter CorC
Avi_0442	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Avi_0443	COG1396	sequence-specific DNA binding
Avi_0444	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Avi_0445	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Avi_0447	COG0071	Belongs to the small heat shock protein (HSP20) family
Avi_0452	COG0840	transmembrane signaling receptor activity
Avi_0453	COG2205	protein histidine kinase activity
Avi_0454	COG0594	ribonuclease P activity
Avi_0455	COG0706	membrane insertase activity
Avi_0456	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Avi_0459	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Avi_0464	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Avi_0465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avi_0470	COG1749	Flagellar hook protein flgE
Avi_0473	COG2171	N-acyltransferase activity
Avi_0474	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Avi_0478	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Avi_0479	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Avi_0481	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Avi_0485	COG0745	RESPONSE REGULATOR receiver
Avi_0488	COG0704	Plays a role in the regulation of phosphate uptake
Avi_0489	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Avi_0493	COG0573	inorganic phosphate transmembrane transporter activity
Avi_0496	COG5002	protein histidine kinase activity
Avi_0497	COG2326	polyphosphate kinase activity
Avi_0501	COG1125	glycine betaine transport
Avi_0501	COG0517	IMP dehydrogenase activity
Avi_0505	COG2188	Transcriptional regulator
Avi_0506	COG2986	histidine ammonia-lyase
Avi_0508	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Avi_0509	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Avi_0511	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Avi_0516	COG0427	acetyl-CoA hydrolase
Avi_0518	COG3938	Belongs to the proline racemase family
Avi_0519	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avi_0520	COG0745	RESPONSE REGULATOR receiver
Avi_0524	COG0418	dihydroorotase activity
Avi_0525	COG3706	GGDEF domain
Avi_0528	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Avi_0534	COG0166	Belongs to the GPI family
Avi_0535	COG0318	PFAM AMP-dependent synthetase and ligase
Avi_0538	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_0540	COG0101	tRNA pseudouridine synthase activity
Avi_0541	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Avi_0542	COG0242	peptide deformylase activity
Avi_0543	COG2967	ApaG domain
Avi_0545	COG0717	Belongs to the dCTP deaminase family
Avi_0547	COG0640	Transcriptional regulator
Avi_0549	COG3293	Transposase
Avi_0554	COG0583	DNA-binding transcription factor activity
Avi_0578	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_0586	COG0167	dihydroorotate dehydrogenase activity
Avi_0597	COG1024	Enoyl-CoA hydratase
Avi_0597	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avi_0598	COG0183	Belongs to the thiolase family
Avi_0599	COG1960	acyl-CoA dehydrogenase activity
Avi_0605	COG1785	Belongs to the alkaline phosphatase family
Avi_0607	COG1136	(ABC) transporter
Avi_0610	COG5001	Diguanylate cyclase
Avi_0610	COG4251	negative regulation of phosphorylation
Avi_0610	COG3706	GGDEF domain
Avi_0610	COG2203	Gaf domain
Avi_0612	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Avi_0615	COG1201	RNA secondary structure unwinding
Avi_0619	COG1047	Peptidyl-prolyl cis-trans
Avi_0620	COG0784	Response regulator, receiver
Avi_0620	COG2198	Histidine kinase
Avi_0620	COG2205	protein histidine kinase activity
Avi_0622	COG1970	mechanosensitive ion channel activity
Avi_0626	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Avi_0631	COG1216	Glycosyl transferase, family 2
Avi_0636	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Avi_0638	COG0424	maF-like protein
Avi_0640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Avi_0642	COG5328	Belongs to the UPF0262 family
Avi_0643	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Avi_0645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Avi_0652	COG1309	transcriptional regulator
Avi_0656	COG2764	glyoxalase bleomycin resistance protein dioxygenase
Avi_0658	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Avi_0662	COG2818	Glycosylase
Avi_0664	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Avi_0669	COG0583	DNA-binding transcription factor activity
Avi_0682	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Avi_0687	COG3436	PFAM IS66 Orf2 family protein
Avi_0688	COG4372	Transposase
Avi_0692	COG3436	PFAM IS66 Orf2 family protein
Avi_0693	COG2433	Pfam Transposase IS66
Avi_0697	COG1404	Belongs to the peptidase S8 family
Avi_0716	COG0488	(ABC) transporter
Avi_0721	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Avi_0722	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Avi_0724	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Avi_0726	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Avi_0728	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Avi_0729	COG4786	Flagellar basal body rod
Avi_0731	COG1157	protein secretion by the type III secretion system
Avi_0735	COG1815	bacterial-type flagellum-dependent cell motility
Avi_0737	COG1558	bacterial-type flagellum-dependent cell motility
Avi_0738	COG1677	Flagellar hook-basal body complex protein FliE
Avi_0740	COG4786	Flagellar basal body rod
Avi_0741	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
Avi_0742	COG1706	bacterial-type flagellum-dependent cell motility
Avi_0744	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Avi_0747	COG1338	Plays a role in the flagellum-specific transport system
Avi_0748	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_0749	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_0750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_0751	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_0752	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_0756	COG1360	Flagellar Motor Protein
Avi_0764	COG1749	Flagellar hook protein flgE
Avi_0765	COG1256	bacterial-type flagellum assembly
Avi_0768	COG5443	negative regulation of bacterial-type flagellum assembly
Avi_0769	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Avi_0770	COG4794	Type iii secretion
Avi_0772	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Avi_0783	COG1609	Transcriptional regulator
Avi_0785	COG1653	transport
Avi_0786	COG1175	transmembrane transport
Avi_0787	COG0395	ABC-type sugar transport system, permease component
Avi_0788	COG0366	Alpha amylase catalytic
Avi_0789	COG3842	ATPase activity
Avi_0792	COG3493	citrate carrier protein
Avi_0796	COG0129	dihydroxy-acid dehydratase activity
Avi_0797	COG0363	glucosamine-6-phosphate deaminase activity
Avi_0798	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Avi_0799	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_0801	COG2081	HI0933 family
Avi_0806	COG2972	Histidine kinase
Avi_0806	COG0840	transmembrane signaling receptor activity
Avi_0811	COG5265	(ABC) transporter
Avi_0816	COG2224	Isocitrate lyase
Avi_0820	COG3842	ATPase activity
Avi_0823	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_0825	COG1177	transmembrane transport
Avi_0827	COG2205	protein histidine kinase activity
Avi_0838	COG1959	2 iron, 2 sulfur cluster binding
Avi_0840	COG3265	gluconokinase activity
Avi_0842	COG2134	cdp-diacylglycerol pyrophosphatase
Avi_0844	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_0846	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Avi_0851	COG0579	oxidoreductase
Avi_0886	COG0582	viral genome integration into host DNA
Avi_0888	COG0248	Ppx GppA phosphatase
Avi_0889	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Avi_0891	COG5001	Diguanylate cyclase
Avi_0891	COG3300	MHYT domain
Avi_0893	COG0784	Response regulator, receiver
Avi_0893	COG5002	protein histidine kinase activity
Avi_0893	COG2198	Histidine kinase
Avi_0895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Avi_0897	COG1663	tetraacyldisaccharide 4'-kinase activity
Avi_0899	COG1519	Transferase
Avi_0903	COG0312	modulator of DNA gyrase
Avi_0904	COG0475	glutathione-regulated potassium exporter activity
Avi_0904	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Avi_0907	COG0742	ribosomal rna small subunit methyltransferase
Avi_0910	COG1187	pseudouridine synthase activity
Avi_0911	COG0590	tRNA wobble adenosine to inosine editing
Avi_0914	COG0477	Major facilitator Superfamily
Avi_0916	COG3386	PFAM SMP-30 Gluconolaconase
Avi_0918	COG2771	luxR family
Avi_0919	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_0919	COG1116	anion transmembrane transporter activity
Avi_0926	COG0598	Magnesium transport protein CorA
Avi_0927	COG3158	transport of potassium into the cell
Avi_0929	COG0356	it plays a direct role in the translocation of protons across the membrane
Avi_0931	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Avi_0934	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Avi_0936	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Avi_0940	COG0521	Mo-molybdopterin cofactor biosynthetic process
Avi_0941	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Avi_0943	COG0142	geranyltranstransferase activity
Avi_0951	COG0752	glycyl-tRNA synthetase alpha subunit
Avi_0955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Avi_0956	COG0751	glycine-tRNA ligase activity
Avi_0957	COG1683	Conserved Protein
Avi_0958	COG0840	transmembrane signaling receptor activity
Avi_0958	COG0840	transmembrane signaling receptor activity
Avi_0960	COG0151	Belongs to the GarS family
Avi_0962	COG2183	response to ionizing radiation
Avi_0963	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Avi_0970	COG0725	ABC transporter, periplasmic molybdate-binding protein
Avi_0972	COG4149	molybdate abc transporter
Avi_0973	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Avi_0976	COG0009	L-threonylcarbamoyladenylate synthase
Avi_0980	COG0840	transmembrane signaling receptor activity
Avi_0981	COG4638	Rieske (2fe-2S)
Avi_0986	COG1960	acyl-CoA dehydrogenase activity
Avi_0987	COG1024	Enoyl-CoA hydratase
Avi_0991	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Avi_0994	COG0840	transmembrane signaling receptor activity
Avi_0997	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Avi_0998	COG1722	exodeoxyribonuclease VII activity
Avi_0999	COG0123	including yeast histone deacetylase and acetoin utilization protein
Avi_1004	COG1268	BioY protein
Avi_1006	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Avi_1007	COG1122	ATPase activity
Avi_1010	COG3214	Protein conserved in bacteria
Avi_1014	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Avi_1014	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Avi_1015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Avi_1017	COG5001	Diguanylate cyclase
Avi_1017	COG3300	MHYT domain
Avi_1021	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Avi_1023	COG0484	heat shock protein binding
Avi_1026	COG0259	pyridoxamine-phosphate oxidase activity
Avi_1028	COG2814	Major facilitator Superfamily
Avi_1029	COG0789	Transcriptional regulator
Avi_1030	COG1686	Belongs to the peptidase S11 family
Avi_1034	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avi_1036	COG0312	modulator of DNA gyrase
Avi_1041	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Avi_1042	COG0109	protoheme IX farnesyltransferase activity
Avi_1044	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Avi_1048	COG3346	SURF1 family
Avi_1052	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Avi_1055	COG1280	lysine exporter protein (LysE YggA)
Avi_1059	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Avi_1060	COG0328	RNA-DNA hybrid ribonuclease activity
Avi_1062	COG0803	Belongs to the bacterial solute-binding protein 9 family
Avi_1067	COG0678	peroxiredoxin activity
Avi_1067	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Avi_1069	COG1678	Uncharacterized ACR, COG1678
Avi_1071	COG0640	Transcriptional regulator
Avi_1072	COG5001	Diguanylate cyclase
Avi_1073	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Avi_1074	COG0612	Peptidase, M16
Avi_1079	COG1597	lipid kinase activity
Avi_1080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avi_1084	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Avi_1092	COG1194	a g-specific adenine glycosylase
Avi_1095	COG1196	nuclear chromosome segregation
Avi_1099	COG2814	Major facilitator Superfamily
Avi_1102	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Avi_1102	COG0574	Belongs to the PEP-utilizing enzyme family
Avi_1113	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_1117	COG0840	transmembrane signaling receptor activity
Avi_1118	COG0175	sulfate reduction
Avi_1120	COG0175	sulfate reduction
Avi_1122	COG2895	sulfate adenylyltransferase (ATP) activity
Avi_1125	COG1609	Transcriptional regulator
Avi_1127	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Avi_1130	COG0693	protein deglycase activity
Avi_1136	COG0038	chloride channel
Avi_1138	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_1144	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Avi_1147	COG1012	belongs to the aldehyde dehydrogenase family
Avi_1148	COG0625	glutathione transferase activity
Avi_1150	COG3119	arylsulfatase activity
Avi_1151	COG1309	transcriptional regulator
Avi_1154	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Avi_1157	COG3293	Transposase
Avi_1159	COG0840	transmembrane signaling receptor activity
Avi_1160	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
Avi_1164	COG1349	DNA-binding transcription factor activity
Avi_1177	COG0477	Major facilitator Superfamily
Avi_1179	COG0778	Nitroreductase
Avi_1186	COG1388	LysM domain
Avi_1186	COG1376	ErfK ybiS ycfS ynhG family protein
Avi_1187	COG1376	ErfK ybiS ycfS ynhG family protein
Avi_1189	COG1846	Transcriptional regulator
Avi_1190	COG1764	response to oxidative stress
Avi_1195	COG4191	Histidine kinase
Avi_1195	COG0784	Response regulator, receiver
Avi_1199	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Avi_1200	COG0840	transmembrane signaling receptor activity
Avi_1201	COG0840	transmembrane signaling receptor activity
Avi_1204	COG0433	COG0433 Predicted ATPase
Avi_1208	COG0840	transmembrane signaling receptor activity
Avi_1209	COG1968	undecaprenyl-diphosphatase activity
Avi_1211	COG4214	carbohydrate transport
Avi_1212	COG4213	ABC transporter substrate-binding protein
Avi_1214	COG1846	Transcriptional regulator
Avi_1214	COG1940	carbohydrate kinase activity
Avi_1218	COG1120	ATPase activity
Avi_1219	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avi_1222	COG2226	methyltransferase
Avi_1224	COG2814	Major facilitator Superfamily
Avi_1225	COG3320	Male sterility
Avi_1225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Avi_1234	COG2010	Cytochrome c
Avi_1239	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Avi_1242	COG1733	regulation of RNA biosynthetic process
Avi_1245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Avi_1249	COG5002	protein histidine kinase activity
Avi_1249	COG5001	Diguanylate cyclase
Avi_1249	COG3447	MASE1 domain protein
Avi_1251	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Avi_1264	COG2514	catechol 2,3-dioxygenase activity
Avi_1265	COG0589	response to stress
Avi_1267	COG3788	relative of glutathione S-transferase, MAPEG superfamily
Avi_1271	COG1272	protein, Hemolysin III
Avi_1273	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avi_1274	COG1247	-acetyltransferase
Avi_1277	COG4957	zinc ion binding
Avi_1278	COG1320	monovalent cation:proton antiporter activity
Avi_1279	COG2212	antiporter activity
Avi_1281	COG1863	multisubunit Na H antiporter MnhE subunit
Avi_1283	COG1006	Multisubunit Na H antiporter MnhC subunit
Avi_1284	COG2111	Na H antiporter
Avi_1286	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Avi_1295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_1296	COG0577	efflux transmembrane transporter activity
Avi_1296	COG1136	(ABC) transporter
Avi_1302	COG2166	iron-sulfur cluster assembly
Avi_1305	COG2205	protein histidine kinase activity
Avi_1308	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avi_1323	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Avi_1324	COG2983	Belongs to the UPF0260 family
Avi_1328	COG0789	Transcriptional regulator
Avi_1334	COG4695	Portal protein
Avi_1358	COG0745	RESPONSE REGULATOR receiver
Avi_1359	COG2205	protein histidine kinase activity
Avi_1362	COG4235	cytochrome complex assembly
Avi_1363	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Avi_1364	COG1138	Cytochrome C-type biogenesis protein
Avi_1365	COG3088	subunit of a heme lyase
Avi_1368	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Avi_1370	COG0745	RESPONSE REGULATOR receiver
Avi_1371	COG2205	protein histidine kinase activity
Avi_1372	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Avi_1373	COG2205	protein histidine kinase activity
Avi_1373	COG2202	Pas domain
Avi_1374	COG0308	aminopeptidase N
Avi_1377	COG3290	protein histidine kinase activity
Avi_1377	COG0840	transmembrane signaling receptor activity
Avi_1385	COG0443	Heat shock 70 kDa protein
Avi_1389	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_1391	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_1393	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Avi_1395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Avi_1398	COG2239	Acts as a magnesium transporter
Avi_1399	COG2814	Major facilitator Superfamily
Avi_1402	COG4172	Belongs to the ABC transporter superfamily
Avi_1403	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_1404	COG0601	transmembrane transport
Avi_1405	COG4166	transmembrane transport
Avi_1406	COG0174	glutamine synthetase
Avi_1409	COG1695	Transcriptional regulator
Avi_1410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Avi_1411	COG0463	Glycosyl transferase, family 2
Avi_1414	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Avi_1416	COG0625	glutathione transferase activity
Avi_1423	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Avi_1431	COG0741	lytic transglycosylase activity
Avi_1432	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_1434	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Avi_1438	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Avi_1438	COG2169	Transcriptional regulator
Avi_1439	COG0840	transmembrane signaling receptor activity
Avi_1441	COG1758	RNA polymerase activity
Avi_1447	COG0681	Belongs to the peptidase S26 family
Avi_1449	COG0571	ribonuclease III activity
Avi_1450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Avi_1451	COG3180	Ammonia monooxygenase
Avi_1452	COG1381	Involved in DNA repair and RecF pathway recombination
Avi_1457	COG1418	mRNA catabolic process
Avi_1461	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Avi_1462	COG0354	folic acid binding
Avi_1466	COG1051	belongs to the nudix hydrolase family
Avi_1470	COG1183	phosphatidylcholine synthase activity
Avi_1471	COG0688	phosphatidylethanolamine metabolic process
Avi_1472	COG5265	(ABC) transporter
Avi_1474	COG1652	LysM domain
Avi_1474	COG2823	Periplasmic or secreted lipoprotein
Avi_1476	COG2962	Rard protein
Avi_1477	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avi_1487	COG0215	cysteine-tRNA ligase activity
Avi_1489	COG5434	Belongs to the glycosyl hydrolase 28 family
Avi_1490	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Avi_1491	COG1088	dTDP-glucose 4,6-dehydratase activity
Avi_1493	COG1091	dTDP-4-dehydrorhamnose reductase activity
Avi_1494	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Avi_1497	COG4221	oxidoreductase activity
Avi_1499	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Avi_1500	COG1286	toxin biosynthetic process
Avi_1502	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Avi_1503	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Avi_1508	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Avi_1509	COG2207	Transcriptional regulator
Avi_1509	COG1917	Cupin 2, conserved barrel domain protein
Avi_1510	COG0765	amino acid transport
Avi_1512	COG0765	amino acid transport
Avi_1515	COG0305	Participates in initiation and elongation during chromosome replication
Avi_1516	COG0359	binds to the 23S rRNA
Avi_1519	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Avi_1520	COG0360	Binds together with S18 to 16S ribosomal RNA
Avi_1526	COG0667	Aldo Keto reductase
Avi_1527	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Avi_1530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Avi_1531	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Avi_1532	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Avi_1534	COG1561	YicC-like family, N-terminal region
Avi_1535	COG0194	GDP metabolic process
Avi_1536	COG0500	methyltransferase
Avi_1537	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Avi_1538	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Avi_1541	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Avi_1544	COG0671	phosphoesterase, PA-phosphatase related
Avi_1545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Avi_1547	COG0840	transmembrane signaling receptor activity
Avi_1547	COG2972	Histidine kinase
Avi_1549	COG0488	(ABC) transporter
Avi_1552	COG0105	UTP biosynthetic process
Avi_1553	COG0314	molybdopterin synthase activity
Avi_1556	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Avi_1558	COG0322	excinuclease ABC activity
Avi_1559	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_1562	COG0625	glutathione transferase activity
Avi_1564	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Avi_1565	COG0243	molybdopterin cofactor binding
Avi_1568	COG3453	Protein conserved in bacteria
Avi_1568	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Avi_1569	COG0640	Transcriptional regulator
Avi_1573	COG0730	response to heat
Avi_1574	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Avi_1575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Avi_1577	COG0628	permease
Avi_1580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Avi_1582	COG0248	Ppx GppA phosphatase
Avi_1583	COG1321	iron dependent repressor
Avi_1584	COG1914	H( )-stimulated, divalent metal cation uptake system
Avi_1588	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Avi_1592	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Avi_1595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Avi_1597	COG3300	MHYT domain
Avi_1597	COG5001	Diguanylate cyclase
Avi_1600	COG2200	EAL domain
Avi_1600	COG2199	diguanylate cyclase activity
Avi_1600	COG2203	Gaf domain
Avi_1601	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Avi_1603	COG0113	porphobilinogen synthase activity
Avi_1610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Avi_1612	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Avi_1613	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Avi_1613	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Avi_1618	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Avi_1620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Avi_1621	COG2814	Major facilitator Superfamily
Avi_1622	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Avi_1628	COG0416	fatty acid biosynthetic process
Avi_1630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Avi_1631	COG0776	regulation of translation
Avi_1637	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Avi_1641	COG1404	Belongs to the peptidase S8 family
Avi_1642	COG0464	growth
Avi_1646	COG3501	Rhs element vgr protein
Avi_1661	COG0438	transferase activity, transferring glycosyl groups
Avi_1670	COG1612	heme a metabolic process
Avi_1671	COG3384	dioxygenase
Avi_1674	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Avi_1675	COG0010	Belongs to the arginase family
Avi_1679	COG2329	Antibiotic biosynthesis monooxygenase
Avi_1681	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Avi_1682	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Avi_1684	COG1832	CoA-binding protein
Avi_1687	COG1832	CoA-binding protein
Avi_1691	COG1408	metallophosphoesterase
Avi_1694	COG2124	cytochrome p450
Avi_1696	COG0740	serine-type endopeptidase activity
Avi_1698	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Avi_1700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Avi_1705	COG1024	Enoyl-CoA hydratase
Avi_1712	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avi_1713	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avi_1714	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avi_1715	COG0649	NAD binding
Avi_1717	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Avi_1718	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Avi_1719	COG0052	Belongs to the universal ribosomal protein uS2 family
Avi_1721	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Avi_1723	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Avi_1726	COG0713	ATP synthesis coupled electron transport
Avi_1729	COG1007	ATP synthesis coupled electron transport
Avi_1735	COG0251	oxidation-reduction process
Avi_1739	COG0442	prolyl-tRNA aminoacylation
Avi_1741	COG1136	(ABC) transporter
Avi_1742	COG0587	DNA-directed DNA polymerase activity
Avi_1745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Avi_1749	COG0784	Response regulator, receiver
Avi_1750	COG0745	RESPONSE REGULATOR receiver
Avi_1750	COG3706	GGDEF domain
Avi_1751	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Avi_1753	COG0477	Major facilitator Superfamily
Avi_1755	COG0557	exoribonuclease II activity
Avi_1756	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Avi_1759	COG0758	DNA mediated transformation
Avi_1760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Avi_1762	COG0540	Belongs to the ATCase OTCase family
Avi_1763	COG1960	acyl-CoA dehydrogenase activity
Avi_1768	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Avi_1769	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Avi_1770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Avi_1773	COG0154	amidase activity
Avi_1776	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Avi_1777	COG3952	Lipid A Biosynthesis
Avi_1777	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avi_1778	COG0463	Glycosyl transferase, family 2
Avi_1781	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Avi_1785	COG4765	Protein conserved in bacteria
Avi_1786	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Avi_1788	COG0511	ligase activity, forming carbon-carbon bonds
Avi_1789	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Avi_1790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Avi_1794	COG1530	ribonuclease E activity
Avi_1794	COG1530	ribonuclease E activity
Avi_1795	COG0860	N-Acetylmuramoyl-L-alanine amidase
Avi_1797	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Avi_1801	COG0284	orotidine-5'-phosphate decarboxylase activity
Avi_1804	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Avi_1810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Avi_1812	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Avi_1819	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Avi_1820	COG0081	regulation of translation
Avi_1822	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Avi_1823	COG0222	ribosome binding
Avi_1826	COG0085	RNA polymerase activity
Avi_1827	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Avi_1833	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Avi_1834	COG0049	tRNA binding
Avi_1835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Avi_1837	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Avi_1839	COG0051	transcription antitermination factor activity, RNA binding
Avi_1840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Avi_1841	COG0088	Forms part of the polypeptide exit tunnel
Avi_1842	COG0089	rRNA binding
Avi_1843	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Avi_1844	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Avi_1845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Avi_1846	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Avi_1847	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Avi_1848	COG0255	Belongs to the universal ribosomal protein uL29 family
Avi_1849	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Avi_1850	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Avi_1851	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Avi_1853	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Avi_1854	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Avi_1855	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Avi_1856	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Avi_1857	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Avi_1859	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Avi_1861	COG1841	ribosomal large subunit assembly
Avi_1862	COG0200	Binds to the 23S rRNA
Avi_1864	COG0563	adenylate kinase activity
Avi_1865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Avi_1866	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Avi_1867	COG0202	RNA polymerase activity
Avi_1869	COG0203	ribosomal protein L17
Avi_1877	COG2897	thiosulfate sulfurtransferase activity
Avi_1879	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Avi_1880	COG0415	Belongs to the DNA photolyase family
Avi_1882	COG0739	heme binding
Avi_1883	COG2833	Protein of unknown function (DUF455)
Avi_1886	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Avi_1891	COG0281	malic enzyme
Avi_1891	COG0280	phosphate acetyltransferase
Avi_1893	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Avi_1894	COG1127	ABC transporter
Avi_1896	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Avi_1896	COG3218	ABC-type transport auxiliary lipoprotein component
Avi_1897	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Avi_1902	COG0047	phosphoribosylformylglycinamidine synthase activity
Avi_1905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Avi_1906	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Avi_1910	COG3706	GGDEF domain
Avi_1913	COG0538	isocitrate dehydrogenase activity
Avi_1915	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Avi_1916	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Avi_1919	COG1253	flavin adenine dinucleotide binding
Avi_1921	COG2755	lipolytic protein G-D-S-L family
Avi_1921	COG0657	acetylesterase activity
Avi_1922	COG2195	Cleaves the N-terminal amino acid of tripeptides
Avi_1926	COG0861	Integral membrane protein TerC family
Avi_1927	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Avi_1928	COG2066	Belongs to the glutaminase family
Avi_1931	COG0037	tRNA processing
Avi_1933	COG0483	inositol monophosphate 1-phosphatase activity
Avi_1934	COG0483	inositol monophosphate 1-phosphatase activity
Avi_1935	COG2814	Major facilitator Superfamily
Avi_1936	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Avi_1941	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Avi_1945	COG0484	heat shock protein binding
Avi_1948	COG0321	lipoyl(octanoyl) transferase activity
Avi_1983	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Avi_1984	COG1091	dTDP-4-dehydrorhamnose reductase activity
Avi_1986	COG1088	dTDP-glucose 4,6-dehydratase activity
Avi_1988	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Avi_2016	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Avi_2018	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Avi_2025	COG0242	peptide deformylase activity
Avi_2028	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Avi_2029	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Avi_2030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Avi_2033	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Avi_2035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Avi_2041	COG0823	Involved in the tonB-independent uptake of proteins
Avi_2042	COG0778	Nitroreductase
Avi_2046	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Avi_2047	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Avi_2051	COG2205	protein histidine kinase activity
Avi_2051	COG2202	Pas domain
Avi_2054	COG1573	uracil-dna glycosylase
Avi_2055	COG1522	sequence-specific DNA binding
Avi_2057	COG2084	Dehydrogenase
Avi_2058	COG2267	carboxylic ester hydrolase activity
Avi_2062	COG5425	PFAM Usg family protein
Avi_2069	COG1763	Mo-molybdopterin cofactor biosynthetic process
Avi_2070	COG0746	molybdenum cofactor guanylyltransferase activity
Avi_2072	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Avi_2075	COG3706	GGDEF domain
Avi_2077	COG0114	fumarate hydratase activity
Avi_2078	COG2989	Protein conserved in bacteria
Avi_2080	COG0546	phosphoglycolate phosphatase activity
Avi_2081	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Avi_2087	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Avi_2098	COG5001	Diguanylate cyclase
Avi_2098	COG2203	Gaf domain
Avi_2098	COG4251	negative regulation of phosphorylation
Avi_2098	COG3706	GGDEF domain
Avi_2099	COG0556	nucleotide-excision repair
Avi_2104	COG3161	chorismate lyase activity
Avi_2107	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Avi_2109	COG0148	phosphopyruvate hydratase activity
Avi_2112	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Avi_2114	COG0508	dehydrogenase complex catalyzes the overall conversion of
Avi_2114	COG0022	dehydrogenase e1 component
Avi_2115	COG0508	dehydrogenase complex catalyzes the overall conversion of
Avi_2120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Avi_2123	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Avi_2124	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Avi_2127	COG0477	Major facilitator Superfamily
Avi_2128	COG2867	negative regulation of translational initiation
Avi_2130	COG1058	Belongs to the CinA family
Avi_2130	COG1546	Belongs to the CinA family
Avi_2131	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Avi_2131	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Avi_2134	COG3852	Histidine kinase
Avi_2135	COG2204	response regulator
Avi_2136	COG5000	phosphorelay sensor kinase activity
Avi_2137	COG2204	response regulator
Avi_2139	COG1923	regulation of RNA biosynthetic process
Avi_2142	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Avi_2144	COG3956	TIGRFAM MazG family protein
Avi_2146	COG1648	precorrin-2 dehydrogenase activity
Avi_2146	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Avi_2152	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_2154	COG1686	Belongs to the peptidase S11 family
Avi_2155	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Avi_2157	COG0730	response to heat
Avi_2158	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Avi_2159	COG0084	hydrolase, TatD family'
Avi_2160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Avi_2160	COG0321	lipoyl(octanoyl) transferase activity
Avi_2162	COG0785	Cytochrome C biogenesis protein
Avi_2163	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_2165	COG1183	phosphatidylcholine synthase activity
Avi_2166	COG1129	ABC transporter
Avi_2170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Avi_2171	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Avi_2178	COG1177	transmembrane transport
Avi_2179	COG4149	molybdate abc transporter
Avi_2180	COG3842	ATPase activity
Avi_2183	COG0523	cobalamin synthesis protein
Avi_2185	COG1121	(ABC) transporter
Avi_2187	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Avi_2188	COG0735	belongs to the Fur family
Avi_2194	COG1686	Belongs to the peptidase S11 family
Avi_2204	COG1752	Esterase of the alpha-beta hydrolase superfamily
Avi_2205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Avi_2207	COG0302	gtp cyclohydrolase
Avi_2209	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Avi_2211	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Avi_2215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Avi_2216	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Avi_2226	COG0187	DNA topoisomerase II activity
Avi_2229	COG0745	RESPONSE REGULATOR receiver
Avi_2229	COG3706	GGDEF domain
Avi_2230	COG0149	triose-phosphate isomerase activity
Avi_2233	COG0504	CTP synthase activity
Avi_2243	COG0633	Ferredoxin
Avi_2252	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Avi_2252	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Avi_2253	COG0509	glycine decarboxylation via glycine cleavage system
Avi_2254	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Avi_2259	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Avi_2261	COG0564	pseudouridine synthase activity
Avi_2262	COG0546	phosphoglycolate phosphatase activity
Avi_2266	COG0477	Major facilitator Superfamily
Avi_2270	COG2003	Belongs to the UPF0758 family
Avi_2271	COG0024	Methionine aminopeptidase
Avi_2273	COG0583	DNA-binding transcription factor activity
Avi_2274	COG2855	membrane
Avi_2275	COG1489	DNA binding
Avi_2276	COG3243	poly(R)-hydroxyalkanoic acid synthase
Avi_2278	COG0436	Aminotransferase
Avi_2280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Avi_2283	COG0346	lactoylglutathione lyase activity
Avi_2286	COG1278	Cold shock
Avi_2290	COG0582	viral genome integration into host DNA
Avi_2294	COG0587	DNA-directed DNA polymerase activity
Avi_2295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Avi_2300	COG1598	PFAM Uncharacterised protein family UPF0150
Avi_2343	COG3646	Phage regulatory protein
Avi_2363	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Avi_2366	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Avi_2368	COG0697	spore germination
Avi_2375	COG0174	glutamine synthetase
Avi_2376	COG0347	Belongs to the P(II) protein family
Avi_2378	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Avi_2378	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Avi_2381	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Avi_2382	COG0629	single-stranded DNA binding
Avi_2385	COG2095	MarC family integral membrane protein
Avi_2386	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Avi_2396	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Avi_2402	COG0395	ABC-type sugar transport system, permease component
Avi_2404	COG3842	ATPase activity
Avi_2408	COG0667	Aldo Keto reductase
Avi_2409	COG3507	Belongs to the glycosyl hydrolase 43 family
Avi_2412	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Avi_2413	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Avi_2414	COG0129	dihydroxy-acid dehydratase activity
Avi_2416	COG1280	lysine exporter protein (LysE YggA)
Avi_2417	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Avi_2423	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Avi_2431	COG0513	Belongs to the DEAD box helicase family
Avi_2432	COG1280	lysine exporter protein (LysE YggA)
Avi_2433	COG2945	thiolester hydrolase activity
Avi_2435	COG0719	Fe-S assembly protein
Avi_2436	COG0396	ATPase activity
Avi_2438	COG0719	Fe-S assembly protein
Avi_2440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Avi_2441	COG2151	metal-sulfur cluster biosynthetic enzyme
Avi_2445	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Avi_2446	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Avi_2448	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Avi_2450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Avi_2451	COG0343	queuine tRNA-ribosyltransferase activity
Avi_2455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Avi_2456	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Avi_2457	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Avi_2459	COG2080	2 iron, 2 sulfur cluster binding
Avi_2467	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Avi_2470	COG3106	COG3106 Predicted ATPase
Avi_2471	COG3768	UPF0283 membrane protein
Avi_2477	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Avi_2478	COG0544	peptidyl-prolyl cis-trans isomerase activity
Avi_2484	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Avi_2485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Avi_2490	COG0252	asparaginase activity
Avi_2492	COG0737	Belongs to the 5'-nucleotidase family
Avi_2495	COG0463	Glycosyl transferase, family 2
Avi_2496	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Avi_2498	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_2499	COG3842	ATPase activity
Avi_2500	COG3665	Urea carboxylase-associated protein
Avi_2506	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Avi_2507	COG2153	protein acetylation
Avi_2508	COG1671	Belongs to the UPF0178 family
Avi_2510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Avi_2511	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avi_2513	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avi_2514	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Avi_2515	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Avi_2517	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Avi_2518	COG0750	zinc metalloprotease
Avi_2520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Avi_2521	COG0233	cytoplasmic translational termination
Avi_2524	COG0528	UMP kinase activity
Avi_2525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Avi_2528	COG0052	Belongs to the universal ribosomal protein uS2 family
Avi_2534	COG0537	adenosine 5'-monophosphoramidase activity
Avi_2538	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Avi_2545	COG2267	carboxylic ester hydrolase activity
Avi_2548	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_2549	COG0626	cystathionine gamma-synthase activity
Avi_2551	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_2552	COG4597	amino acid ABC transporter
Avi_2553	COG0765	amino acid transport
Avi_2554	COG1126	abc transporter atp-binding protein
Avi_2557	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Avi_2558	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Avi_2560	COG2313	pseudouridylate synthase activity
Avi_2561	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Avi_2562	COG0658	competence protein
Avi_2562	COG2333	competence protein COMEC
Avi_2563	COG0372	Belongs to the citrate synthase family
Avi_2566	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Avi_2567	COG0134	indole-3-glycerol-phosphate synthase activity
Avi_2568	COG0315	cyclic pyranopterin monophosphate synthase activity
Avi_2569	COG0303	'Molybdopterin
Avi_2570	COG0671	phosphoesterase, PA-phosphatase related
Avi_2571	COG1492	cobalamin metabolic process
Avi_2574	COG4176	ABC-type proline glycine betaine transport system permease component
Avi_2575	COG4175	Glycine betaine
Avi_2575	COG0517	IMP dehydrogenase activity
Avi_2581	COG3698	Phosphodiester glycosidase
Avi_2586	COG0583	DNA-binding transcription factor activity
Avi_2594	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avi_2598	COG0681	Belongs to the peptidase S26 family
Avi_2599	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Avi_2600	COG0840	transmembrane signaling receptor activity
Avi_2602	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Avi_2606	COG1058	Belongs to the CinA family
Avi_2606	COG1546	Belongs to the CinA family
Avi_2608	COG0840	transmembrane signaling receptor activity
Avi_2608	COG2972	Histidine kinase
Avi_2609	COG0835	chemotaxis
Avi_2612	COG1760	l-serine dehydratase
Avi_2620	COG2239	Acts as a magnesium transporter
Avi_2627	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
Avi_2628	COG2099	Precorrin-6x reductase
Avi_2630	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Avi_2632	COG1957	nucleoside hydrolase
Avi_2635	COG2875	Belongs to the precorrin methyltransferase family
Avi_2654	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Avi_2663	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Avi_2664	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Avi_2665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Avi_2666	COG0805	protein transport
Avi_2667	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Avi_2668	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Avi_2670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Avi_2671	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Avi_2673	COG1472	Belongs to the glycosyl hydrolase 3 family
Avi_2675	COG0018	arginyl-trna synthetase
Avi_2676	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Avi_2678	COG0316	Belongs to the HesB IscA family
Avi_2683	COG0525	valine-tRNA ligase activity
Avi_2687	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Avi_2694	COG0584	glycerophosphoryl diester phosphodiesterase
Avi_2696	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_2698	COG4608	Belongs to the ABC transporter superfamily
Avi_2704	COG0583	DNA-binding transcription factor activity
Avi_2706	COG3842	ATPase activity
Avi_2707	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_2708	COG1177	transmembrane transport
Avi_2714	COG3547	Transposase (IS116 IS110 IS902 family)
Avi_2722	COG0842	Transport permease protein
Avi_2723	COG1131	(ABC) transporter
Avi_2729	COG2226	methyltransferase
Avi_2730	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Avi_2730	COG3264	Mechanosensitive ion channel
Avi_2734	COG4558	Periplasmic binding protein
Avi_2735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avi_2736	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Avi_2742	COG0270	DNA (cytosine-5-)-methyltransferase activity
Avi_2743	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Avi_2753	COG2801	Transposase and inactivated derivatives
Avi_2758	COG3501	Rhs element vgr protein
Avi_2772	COG0384	phenazine biosynthesis protein PhzF
Avi_2778	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Avi_2782	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Avi_2786	COG1522	sequence-specific DNA binding
Avi_2787	COG1794	racemase activity, acting on amino acids and derivatives
Avi_2789	COG1309	transcriptional regulator
Avi_2790	COG2814	Major facilitator Superfamily
Avi_2792	COG1733	regulation of RNA biosynthetic process
Avi_2794	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Avi_2795	COG0789	Transcriptional regulator
Avi_2796	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Avi_2798	COG0656	L-ascorbic acid biosynthetic process
Avi_2802	COG0028	Belongs to the TPP enzyme family
Avi_2808	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Avi_2809	COG0560	Phosphoserine phosphatase
Avi_2809	COG3830	Belongs to the UPF0237 family
Avi_2816	COG0330	HflC and HflK could
Avi_2820	COG2259	Doxx family
Avi_2822	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Avi_2829	COG0277	FAD linked oxidase domain protein
Avi_2830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Avi_2831	COG0581	inorganic phosphate transmembrane transporter activity
Avi_2832	COG0573	inorganic phosphate transmembrane transporter activity
Avi_2833	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Avi_2843	COG4993	Dehydrogenase
Avi_2845	COG1335	isochorismatase
Avi_2846	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Avi_2847	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Avi_2849	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Avi_2857	COG2264	protein methyltransferase activity
Avi_2858	COG1999	signal sequence binding
Avi_2860	COG0840	transmembrane signaling receptor activity
Avi_2861	COG0835	chemotaxis
Avi_2865	COG2176	DNA-directed DNA polymerase activity
Avi_2869	COG0840	transmembrane signaling receptor activity
Avi_2870	COG0456	acetyltransferase
Avi_2876	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Avi_2878	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Avi_2880	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Avi_2882	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Avi_2884	COG0849	cell division
Avi_2885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Avi_2887	COG1181	Belongs to the D-alanine--D-alanine ligase family
Avi_2888	COG0477	Major facilitator Superfamily
Avi_2889	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Avi_2890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Avi_2891	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Avi_2893	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Avi_2894	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Avi_2896	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Avi_2899	COG2001	Belongs to the MraZ family
Avi_2900	COG0275	rRNA processing
Avi_2906	COG3023	N-Acetylmuramoyl-L-alanine amidase
Avi_2926	COG2226	methyltransferase
Avi_2927	COG0840	transmembrane signaling receptor activity
Avi_2928	COG0840	transmembrane signaling receptor activity
Avi_2928	COG2972	Histidine kinase
Avi_2931	COG2267	carboxylic ester hydrolase activity
Avi_2932	COG0697	spore germination
Avi_2933	COG0028	Belongs to the TPP enzyme family
Avi_2935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Avi_2936	COG0251	oxidation-reduction process
Avi_2943	COG1376	ErfK ybiS ycfS ynhG family protein
Avi_2949	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Avi_2950	COG4149	molybdate abc transporter
Avi_2955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Avi_2957	COG2197	response regulator
Avi_2958	COG1396	sequence-specific DNA binding
Avi_2977	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Avi_2978	COG0697	spore germination
Avi_2998	COG4387	Mu-like prophage protein GP36
Avi_3001	COG4397	Mu-like prophage major head subunit gpT
Avi_3006	COG4383	Mu-like prophage protein gp29
Avi_3008	COG4373	Mu-like prophage FluMu protein gp28
Avi_3078	COG0443	Heat shock 70 kDa protein
Avi_3086	COG1278	Cold shock
Avi_3095	COG0432	Pfam Uncharacterised protein family UPF0047
Avi_3099	COG0583	DNA-binding transcription factor activity
Avi_3102	COG1473	amidohydrolase
Avi_3104	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Avi_3107	COG1268	BioY protein
Avi_3108	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Avi_3111	COG0505	Belongs to the CarA family
Avi_3112	COG0534	Mate efflux family protein
Avi_3113	COG0583	DNA-binding transcription factor activity
Avi_3114	COG0667	Aldo Keto reductase
Avi_3115	COG2321	neutral zinc metallopeptidase
Avi_3122	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Avi_3127	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Avi_3137	COG4641	Protein conserved in bacteria
Avi_3137	COG0438	transferase activity, transferring glycosyl groups
Avi_3138	COG1522	sequence-specific DNA binding
Avi_3139	COG0492	ferredoxin-NADP+ reductase activity
Avi_3141	COG0583	DNA-binding transcription factor activity
Avi_3142	COG0640	Transcriptional regulator
Avi_3143	COG1902	pentaerythritol trinitrate reductase activity
Avi_3147	COG0387	Pfam Sodium calcium exchanger
Avi_3156	COG1278	Cold shock
Avi_3159	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Avi_3163	COG1846	Transcriptional regulator
Avi_3164	COG0745	RESPONSE REGULATOR receiver
Avi_3166	COG2205	protein histidine kinase activity
Avi_3167	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Avi_3171	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Avi_3174	COG0006	proline dipeptidase activity
Avi_3177	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Avi_3181	COG1012	belongs to the aldehyde dehydrogenase family
Avi_3185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Avi_3190	COG0193	aminoacyl-tRNA hydrolase activity
Avi_3193	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Avi_3194	COG0012	GTP binding
Avi_3198	COG0386	Belongs to the glutathione peroxidase family
Avi_3201	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Avi_3203	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Avi_3203	COG2857	Cytochrome c1
Avi_3208	COG1132	(ABC) transporter
Avi_3213	COG1132	(ABC) transporter
Avi_3216	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Avi_3219	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Avi_3221	COG0408	coproporphyrinogen oxidase activity
Avi_3226	COG0617	tRNA 3'-terminal CCA addition
Avi_3229	COG0714	Associated with various cellular activities
Avi_3235	COG0454	-acetyltransferase
Avi_3241	COG0435	Glutathione S-transferase
Avi_3244	COG0740	serine-type endopeptidase activity
Avi_3247	COG3135	benzoate transporter
Avi_3249	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Avi_3254	COG3501	Rhs element vgr protein
Avi_3259	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Avi_3259	COG0512	Glutamine amidotransferase of anthranilate synthase
Avi_3261	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Avi_3262	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Avi_3269	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Avi_3272	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Avi_3273	COG2197	response regulator
Avi_3277	COG1435	thymidine kinase activity
Avi_3283	COG4175	Glycine betaine
Avi_3297	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Avi_3299	COG4115	mRNA cleavage
Avi_3300	COG0366	Alpha amylase catalytic
Avi_3302	COG1160	GTP binding
Avi_3309	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
Avi_3313	COG0024	Methionine aminopeptidase
Avi_3316	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Avi_3319	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_3321	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Avi_3323	COG0457	Tetratricopeptide repeat
Avi_3324	COG0583	DNA-binding transcription factor activity
Avi_3326	COG0402	S-adenosylhomocysteine deaminase activity
Avi_3327	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_3330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_3331	COG0137	argininosuccinate synthase activity
Avi_3340	COG2351	hydroxyisourate hydrolase activity
Avi_3341	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
Avi_3342	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Avi_3344	COG0174	glutamine synthetase
Avi_3347	COG3195	allantoin biosynthetic process
Avi_3347	COG3648	Uricase
Avi_3348	COG1064	alcohol dehydrogenase
Avi_3353	COG3706	GGDEF domain
Avi_3358	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_3359	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_3359	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Avi_3362	COG0513	Belongs to the DEAD box helicase family
Avi_3369	COG1733	regulation of RNA biosynthetic process
Avi_3374	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Avi_3377	COG1982	Orn Lys Arg decarboxylase major
Avi_3392	COG3501	Rhs element vgr protein
Avi_3404	COG0686	Belongs to the AlaDH PNT family
Avi_3407	COG4372	Transposase
Avi_3408	COG3436	PFAM IS66 Orf2 family protein
Avi_3412	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Avi_3414	COG0028	Belongs to the TPP enzyme family
Avi_3414	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
Avi_3433	COG0583	DNA-binding transcription factor activity
Avi_3437	COG2308	Evidence 4 Homologs of previously reported genes of
Avi_3444	COG2346	COG2346, Truncated hemoglobins
Avi_3448	COG0493	'glutamate synthase
Avi_3453	COG1309	transcriptional regulator
Avi_3459	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_3460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_3461	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_3468	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Avi_3469	COG0830	nickel cation binding
Avi_3470	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Avi_3471	COG5001	Diguanylate cyclase
Avi_3471	COG5002	protein histidine kinase activity
Avi_3477	COG0804	urea catabolic process
Avi_3478	COG1442	glycosyl transferase family 8
Avi_3481	COG3755	Protein conserved in bacteria
Avi_3482	COG0832	Belongs to the urease beta subunit family
Avi_3484	COG3813	Protein conserved in bacteria
Avi_3485	COG0831	urea catabolic process
Avi_3486	COG0829	nickel cation binding
Avi_3496	COG4251	negative regulation of phosphorylation
Avi_3506	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Avi_3507	COG2894	cell division
Avi_3508	COG0850	regulation of cytokinetic process
Avi_3513	COG0411	ABC transporter
Avi_3518	COG2814	Major facilitator Superfamily
Avi_3520	COG1218	3'(2'),5'-bisphosphate nucleotidase
Avi_3534	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Avi_3536	COG0564	pseudouridine synthase activity
Avi_3537	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Avi_3537	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_3538	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Avi_3540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Avi_3544	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Avi_3546	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Avi_3551	COG1116	anion transmembrane transporter activity
Avi_3553	COG0402	S-adenosylhomocysteine deaminase activity
Avi_3554	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Avi_3555	COG2249	NAD(P)H dehydrogenase (quinone) activity
Avi_3560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Avi_3568	COG1175	transmembrane transport
Avi_3573	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Avi_3576	COG0482	sulfurtransferase activity
Avi_3577	COG4774	siderophore transport
Avi_3581	COG1120	ATPase activity
Avi_3585	COG4774	siderophore transport
Avi_3592	COG1294	oxidase, subunit
Avi_3593	COG1271	oxidase subunit
Avi_3595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Avi_3603	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_3604	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Avi_3605	COG0632	four-way junction helicase activity
Avi_3606	COG2002	toxin-antitoxin pair type II binding
Avi_3609	COG2255	four-way junction helicase activity
Avi_3610	COG1408	metallophosphoesterase
Avi_3611	COG0494	nUDIX hydrolase
Avi_3616	COG0824	Thioesterase
Avi_3621	COG0823	Involved in the tonB-independent uptake of proteins
Avi_3622	COG2885	chlorophyll binding
Avi_3626	COG0037	tRNA processing
Avi_3627	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Avi_3629	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Avi_3631	COG0217	transcriptional regulatory protein
Avi_3647	COG0840	transmembrane signaling receptor activity
Avi_3649	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Avi_3650	COG1692	metallophosphoesterase
Avi_3651	COG0126	phosphoglycerate kinase activity
Avi_3652	COG3588	fructose-bisphosphate aldolase
Avi_3665	COG0254	rRNA binding
Avi_3667	COG1132	(ABC) transporter
Avi_3672	COG0483	inositol monophosphate 1-phosphatase activity
Avi_3675	COG0352	thiamine-phosphate diphosphorylase activity
Avi_3678	COG0640	Transcriptional regulator
Avi_3683	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Avi_3684	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Avi_3686	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Avi_3687	COG0457	Tetratricopeptide repeat
Avi_3689	COG0596	Alpha beta hydrolase
Avi_3690	COG0469	pyruvate kinase activity
Avi_3695	COG3750	Belongs to the UPF0335 family
Avi_3703	COG0512	Glutamine amidotransferase of anthranilate synthase
Avi_3703	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Avi_3704	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Avi_3707	COG5310	Homospermidine synthase
Avi_3711	COG0737	Belongs to the 5'-nucleotidase family
Avi_3712	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Avi_3714	COG0840	transmembrane signaling receptor activity
Avi_3716	COG0602	queuosine metabolic process
Avi_3717	COG0720	synthase
Avi_3719	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Avi_3720	COG0330	HflC and HflK could
Avi_3722	COG0517	IMP dehydrogenase activity
Avi_3722	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Avi_3724	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Avi_3727	COG2951	lytic endotransglycosylase activity
Avi_3729	COG0840	transmembrane signaling receptor activity
Avi_3732	COG1487	ribonuclease activity
Avi_3734	COG0070	glutamate synthase
Avi_3734	COG0069	glutamate synthase activity
Avi_3734	COG0067	glutamate synthase
Avi_3739	COG0071	Belongs to the small heat shock protein (HSP20) family
Avi_3749	COG0668	transmembrane transport
Avi_3751	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Avi_3751	COG0662	Cupin 2, conserved barrel domain protein
Avi_3754	COG2308	Evidence 4 Homologs of previously reported genes of
Avi_3754	COG2307	Protein conserved in bacteria
Avi_3758	COG0058	SHG alpha-glucan phosphorylase activity
Avi_3760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Avi_3761	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Avi_3762	COG0297	glycogen (starch) synthase activity
Avi_3763	COG0033	Phosphoglucomutase
Avi_3774	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_3775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Avi_3777	COG0446	pyridine nucleotide-disulphide oxidoreductase
Avi_3777	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Avi_3780	COG1733	regulation of RNA biosynthetic process
Avi_3781	COG3041	Addiction module toxin RelE StbE family
Avi_3782	COG3077	Addiction module antitoxin, RelB DinJ family
Avi_3789	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Avi_3790	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Avi_3791	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avi_3792	COG1609	Transcriptional regulator
Avi_3793	COG1846	Transcriptional regulator
Avi_3796	COG0523	cobalamin synthesis protein
Avi_3799	COG2972	Histidine kinase
Avi_3799	COG0840	transmembrane signaling receptor activity
Avi_3800	COG3047	cAMP biosynthetic process
Avi_3808	COG0583	DNA-binding transcription factor activity
Avi_3816	COG0800	Aldolase
Avi_3821	COG2378	regulation of single-species biofilm formation
Avi_3825	COG2199	diguanylate cyclase activity
Avi_3825	COG2202	Pas domain
Avi_3825	COG2200	EAL domain
Avi_3830	COG0673	inositol 2-dehydrogenase activity
Avi_3832	COG2115	Belongs to the xylose isomerase family
Avi_3833	COG1070	Carbohydrate kinase
Avi_3834	COG1609	Transcriptional regulator
Avi_3838	COG1309	transcriptional regulator
Avi_3839	COG1253	flavin adenine dinucleotide binding
Avi_3845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Avi_3850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Avi_3856	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Avi_3858	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Avi_3860	COG0471	metal ion transport
Avi_3860	COG3273	potassium ion transport
Avi_3863	COG2274	protein secretion by the type I secretion system
Avi_3871	COG4172	Belongs to the ABC transporter superfamily
Avi_3872	COG1473	amidohydrolase
Avi_3876	COG0601	transmembrane transport
Avi_3878	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_3879	COG0842	Transport permease protein
Avi_3880	COG0842	Transport permease protein
Avi_3880	COG1129	ABC transporter
Avi_3881	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_3883	COG3454	Phosphonate metabolism
Avi_3884	COG4608	Belongs to the ABC transporter superfamily
Avi_3885	COG0444	Belongs to the ABC transporter superfamily
Avi_3887	COG0601	transmembrane transport
Avi_3888	COG0747	negative chemotaxis
Avi_3890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avi_3891	COG1802	Transcriptional regulator
Avi_3892	COG1904	glucuronate isomerase
Avi_3893	COG1917	Cupin 2, conserved barrel domain protein
Avi_3895	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_3896	COG0246	Mannitol dehydrogenase
Avi_3897	COG1312	Catalyzes the dehydration of D-mannonate
Avi_3898	COG2721	sulfolactate sulfo-lyase activity
Avi_3899	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Avi_3903	COG4213	ABC transporter substrate-binding protein
Avi_3905	COG1129	ABC transporter
Avi_3906	COG4214	carbohydrate transport
Avi_3914	COG3734	2-keto-3-deoxy-galactonokinase
Avi_3915	COG0800	Aldolase
Avi_3917	COG2832	Protein of unknown function (DUF454)
Avi_3918	COG0697	spore germination
Avi_3919	COG2186	Transcriptional regulator
Avi_3920	COG2807	transmembrane transport
Avi_3921	COG2373	Large extracellular alpha-helical protein
Avi_3922	COG4953	penicillin-binding protein 1C
Avi_3923	COG2972	Histidine kinase
Avi_3923	COG0840	transmembrane signaling receptor activity
Avi_3924	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avi_3926	COG0438	transferase activity, transferring glycosyl groups
Avi_3928	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_3929	COG0601	transmembrane transport
Avi_3931	COG0747	negative chemotaxis
Avi_3935	COG0438	transferase activity, transferring glycosyl groups
Avi_3946	COG0419	ATPase involved in DNA repair
Avi_3947	COG0840	transmembrane signaling receptor activity
Avi_3951	COG0542	response to heat
Avi_3954	COG2890	protein-(glutamine-N5) methyltransferase activity
Avi_3955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Avi_3957	COG0527	aspartate kinase activity
Avi_3965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Avi_3968	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Avi_3969	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Avi_3971	COG2226	methyltransferase
Avi_3976	COG0494	nUDIX hydrolase
Avi_3979	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Avi_3981	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Avi_3982	COG0653	protein targeting
Avi_3985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Avi_3989	COG2801	Transposase and inactivated derivatives
Avi_3993	COG0667	Aldo Keto reductase
Avi_4004	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Avi_4006	COG0300	oxidoreductase activity
Avi_4010	COG2086	electron transfer activity
Avi_4013	COG0840	transmembrane signaling receptor activity
Avi_4013	COG2972	Histidine kinase
Avi_4015	COG1250	3-hydroxyacyl-CoA dehydrogenase
Avi_4016	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Avi_4017	COG0165	Argininosuccinate lyase
Avi_4020	COG0019	diaminopimelate decarboxylase activity
Avi_4027	COG2884	Cell division ATP-binding protein ftsE
Avi_4031	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Avi_4033	COG0287	Prephenate dehydrogenase
Avi_4034	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Avi_4035	COG2226	methyltransferase
Avi_4036	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Avi_4041	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Avi_4043	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Avi_4051	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Avi_4053	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Avi_4056	COG4974	Belongs to the 'phage' integrase family
Avi_4057	COG0825	malonyl-CoA metabolic process
Avi_4058	COG3034	peptidoglycan biosynthetic process
Avi_4060	COG0523	cobalamin synthesis protein
Avi_4061	COG1686	Belongs to the peptidase S11 family
Avi_4064	COG0628	permease
Avi_4066	COG2771	luxR family
Avi_4068	COG1766	The M ring may be actively involved in energy transduction
Avi_4071	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Avi_4072	COG0745	RESPONSE REGULATOR receiver
Avi_4073	COG2201	protein-glutamate methylesterase activity
Avi_4074	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Avi_4076	COG0835	chemotaxis
Avi_4077	COG0643	Histidine kinase
Avi_4077	COG2198	Histidine kinase
Avi_4081	COG0840	transmembrane signaling receptor activity
Avi_4083	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Avi_4085	COG0156	8-amino-7-oxononanoate synthase activity
Avi_4088	COG0729	surface antigen
Avi_4092	COG0835	chemotaxis
Avi_4096	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Avi_4097	COG3383	formate dehydrogenase (NAD+) activity
Avi_4102	COG0640	Transcriptional regulator
Avi_4103	COG0039	L-malate dehydrogenase activity
Avi_4104	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Avi_4106	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Avi_4107	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Avi_4108	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Avi_4110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Avi_4113	COG0840	transmembrane signaling receptor activity
Avi_4114	COG4974	Belongs to the 'phage' integrase family
Avi_4121	COG0508	dehydrogenase complex catalyzes the overall conversion of
Avi_4124	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Avi_4127	COG0045	succinate-CoA ligase (ADP-forming) activity
Avi_4129	COG0039	L-malate dehydrogenase activity
Avi_4130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Avi_4139	COG2264	protein methyltransferase activity
Avi_4143	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Avi_4144	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Avi_4145	COG0181	hydroxymethylbilane synthase activity
Avi_4153	COG1872	DUF167
Avi_4154	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Avi_4158	COG0339	signal peptide processing
Avi_4161	COG0137	argininosuccinate synthase activity
Avi_4162	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_4164	COG1280	lysine exporter protein (LysE YggA)
Avi_4168	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Avi_4174	COG2154	pterin-4-alpha-carbinolamine dehydratase
Avi_4176	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Avi_4180	COG1136	(ABC) transporter
Avi_4181	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Avi_4182	COG0670	Belongs to the BI1 family
Avi_4187	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Avi_4188	COG4133	protoheme IX ABC transporter activity
Avi_4189	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Avi_4191	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Avi_4195	COG2917	probably involved in intracellular septation
Avi_4196	COG0552	protein localization to endoplasmic reticulum
Avi_4197	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Avi_4198	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Avi_4203	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Avi_4204	COG0287	Prephenate dehydrogenase
Avi_4204	COG1605	Chorismate mutase
Avi_4205	COG0228	four-way junction DNA binding
Avi_4207	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Avi_4208	COG0336	Belongs to the RNA methyltransferase TrmD family
Avi_4210	COG0335	large ribosomal subunit rRNA binding
Avi_4214	COG2372	response to copper ion
Avi_4216	COG2372	response to copper ion
Avi_4216	COG1276	copper resistance
Avi_4217	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_4218	COG0765	amino acid transport
Avi_4223	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Avi_4227	COG0745	RESPONSE REGULATOR receiver
Avi_4235	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Avi_4236	COG1674	ftsk spoiiie
Avi_4237	COG0004	ammonium transporteR
Avi_4239	COG0347	Belongs to the P(II) protein family
Avi_4240	COG1946	Acyl-CoA thioesterase
Avi_4242	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_4243	COG2835	tetraacyldisaccharide 4'-kinase activity
Avi_4244	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Avi_4245	COG3118	belongs to the thioredoxin family
Avi_4249	COG2017	converts alpha-aldose to the beta-anomer
Avi_4253	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Avi_4259	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Avi_4268	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Avi_4269	COG4783	chaperone-mediated protein folding
Avi_4270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Avi_4277	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Avi_4278	COG0799	negative regulation of ribosome biogenesis
Avi_4279	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Avi_4280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Avi_4281	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Avi_4282	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Avi_4287	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Avi_4288	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Avi_4292	COG0138	bifunctional purine biosynthesis protein purh
Avi_4295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Avi_4295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Avi_4296	COG0501	Belongs to the peptidase M48B family
Avi_4300	COG0793	Belongs to the peptidase S41A family
Avi_4302	COG0494	nUDIX hydrolase
Avi_4303	COG1192	Involved in chromosome partitioning
Avi_4309	COG2201	protein-glutamate methylesterase activity
Avi_4310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Avi_4311	COG0835	chemotaxis
Avi_4312	COG0840	transmembrane signaling receptor activity
Avi_4313	COG3290	protein histidine kinase activity
Avi_4313	COG0840	transmembrane signaling receptor activity
Avi_4314	COG0840	transmembrane signaling receptor activity
Avi_4315	COG0835	chemotaxis
Avi_4316	COG2198	Histidine kinase
Avi_4316	COG0643	Histidine kinase
Avi_4317	COG0745	RESPONSE REGULATOR receiver
Avi_4324	COG1522	sequence-specific DNA binding
Avi_4328	COG4221	oxidoreductase activity
Avi_4329	COG0156	8-amino-7-oxononanoate synthase activity
Avi_4331	COG0738	Major facilitator superfamily
Avi_4332	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Avi_4333	COG2885	chlorophyll binding
Avi_4337	COG0142	geranyltranstransferase activity
Avi_4339	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Avi_4342	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Avi_4343	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Avi_4344	COG0183	Belongs to the thiolase family
Avi_4356	COG2301	Belongs to the HpcH HpaI aldolase family
Avi_4358	COG0066	3-isopropylmalate dehydratase activity
Avi_4359	COG0473	3-isopropylmalate dehydrogenase activity
Avi_4360	COG0671	phosphoesterase, PA-phosphatase related
Avi_4363	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Avi_4365	COG2010	Cytochrome c
Avi_4366	COG0288	reversible hydration of carbon dioxide
Avi_4367	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Avi_4368	COG2902	Dehydrogenase
Avi_4370	COG3459	Glycosyltransferase 36 associated
Avi_4372	COG1473	amidohydrolase
Avi_4375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Avi_4377	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Avi_4380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Avi_4381	COG0495	leucyl-tRNA aminoacylation
Avi_4385	COG1475	DNA binding
Avi_4386	COG1192	Involved in chromosome partitioning
Avi_4387	COG0357	Ribosomal RNA small subunit methyltransferase G
Avi_4389	COG0445	tRNA wobble uridine modification
Avi_4390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Avi_4391	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Avi_4393	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Avi_5000	COG1192	Involved in chromosome partitioning
Avi_5001	COG1475	DNA binding
Avi_5002	COG1414	Transcriptional regulator
Avi_5003	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Avi_5004	COG0392	lysyltransferase activity
Avi_5006	COG3257	ureidoglycine aminohydrolase activity
Avi_5010	COG1522	sequence-specific DNA binding
Avi_5015	COG4215	(ABC) transporter
Avi_5017	COG2040	homocysteine
Avi_5018	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avi_5021	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Avi_5022	COG1473	amidohydrolase
Avi_5024	COG0297	glycogen (starch) synthase activity
Avi_5030	COG1063	alcohol dehydrogenase
Avi_5031	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avi_5032	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5034	COG3265	gluconokinase activity
Avi_5035	COG2084	Dehydrogenase
Avi_5038	COG1609	Transcriptional regulator
Avi_5042	COG1129	ABC transporter
Avi_5046	COG1879	ABC-type sugar transport system periplasmic component
Avi_5049	COG1129	ABC transporter
Avi_5050	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5051	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5052	COG2186	Transcriptional regulator
Avi_5053	COG1012	belongs to the aldehyde dehydrogenase family
Avi_5054	COG1012	belongs to the aldehyde dehydrogenase family
Avi_5056	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Avi_5058	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_5063	COG0778	Nitroreductase
Avi_5066	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Avi_5067	COG0659	secondary active sulfate transmembrane transporter activity
Avi_5068	COG0589	response to stress
Avi_5082	COG0179	Fumarylacetoacetate (FAA) hydrolase
Avi_5085	COG1802	Transcriptional regulator
Avi_5086	COG0747	negative chemotaxis
Avi_5087	COG2723	6-phospho-beta-galactosidase activity
Avi_5088	COG0601	transmembrane transport
Avi_5090	COG3964	amidohydrolase
Avi_5094	COG1921	L-seryl-tRNASec selenium transferase activity
Avi_5096	COG2203	Gaf domain
Avi_5096	COG4251	negative regulation of phosphorylation
Avi_5096	COG5001	Diguanylate cyclase
Avi_5096	COG3706	GGDEF domain
Avi_5103	COG2080	2 iron, 2 sulfur cluster binding
Avi_5106	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Avi_5107	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Avi_5113	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5114	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Avi_5115	COG1486	melibiose metabolic process
Avi_5116	COG4172	Belongs to the ABC transporter superfamily
Avi_5117	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5118	COG0601	transmembrane transport
Avi_5120	COG0747	negative chemotaxis
Avi_5121	COG1486	melibiose metabolic process
Avi_5122	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Avi_5122	COG2207	Transcriptional regulator
Avi_5125	COG0745	RESPONSE REGULATOR receiver
Avi_5128	COG1063	alcohol dehydrogenase
Avi_5129	COG4948	Mandelate Racemase Muconate Lactonizing
Avi_5134	COG4214	carbohydrate transport
Avi_5135	COG1129	ABC transporter
Avi_5138	COG1175	transmembrane transport
Avi_5139	COG0395	ABC-type sugar transport system, permease component
Avi_5143	COG1609	Transcriptional regulator
Avi_5148	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5150	COG0410	ABC transporter
Avi_5151	COG0840	transmembrane signaling receptor activity
Avi_5151	COG2972	Histidine kinase
Avi_5157	COG0667	Aldo Keto reductase
Avi_5160	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5162	COG4213	ABC transporter substrate-binding protein
Avi_5167	COG1129	ABC transporter
Avi_5168	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5169	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5172	COG0765	amino acid transport
Avi_5173	COG1126	abc transporter atp-binding protein
Avi_5175	COG2079	MmgE PrpD family protein
Avi_5179	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_5182	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5184	COG0747	negative chemotaxis
Avi_5188	COG2197	response regulator
Avi_5189	COG5002	protein histidine kinase activity
Avi_5189	COG3850	Histidine kinase
Avi_5190	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Avi_5192	COG2731	YhcH YjgK YiaL family protein
Avi_5193	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_5194	COG2271	Major facilitator Superfamily
Avi_5195	COG1609	Transcriptional regulator
Avi_5196	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_5198	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_5199	COG1473	amidohydrolase
Avi_5208	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_5209	COG2205	protein histidine kinase activity
Avi_5210	COG0745	RESPONSE REGULATOR receiver
Avi_5212	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avi_5217	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Avi_5219	COG1960	acyl-CoA dehydrogenase activity
Avi_5228	COG2207	Transcriptional regulator
Avi_5230	COG0235	Class ii aldolase
Avi_5231	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Avi_5235	COG4221	oxidoreductase activity
Avi_5243	COG1595	DNA-templated transcription, initiation
Avi_5247	COG2824	Alkylphosphonate utilization operon protein PhnA
Avi_5253	COG3833	ABC-type maltose transport systems, permease component
Avi_5254	COG3842	ATPase activity
Avi_5255	COG0584	glycerophosphoryl diester phosphodiesterase
Avi_5263	COG1320	monovalent cation:proton antiporter activity
Avi_5264	COG2212	antiporter activity
Avi_5265	COG1863	multisubunit Na H antiporter MnhE subunit
Avi_5266	COG0651	ATP synthesis coupled electron transport
Avi_5268	COG1006	Multisubunit Na H antiporter MnhC subunit
Avi_5269	COG2111	Na H antiporter
Avi_5269	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Avi_5276	COG0402	S-adenosylhomocysteine deaminase activity
Avi_5281	COG2072	flavoprotein involved in K transport
Avi_5282	COG1177	transmembrane transport
Avi_5283	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_5284	COG3842	ATPase activity
Avi_5285	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Avi_5286	COG0583	DNA-binding transcription factor activity
Avi_5290	COG0601	transmembrane transport
Avi_5293	COG4608	Belongs to the ABC transporter superfamily
Avi_5300	COG0601	transmembrane transport
Avi_5301	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5307	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_5308	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5309	COG1846	Transcriptional regulator
Avi_5317	COG0625	glutathione transferase activity
Avi_5321	COG2133	pyrroloquinoline quinone binding
Avi_5324	COG0438	transferase activity, transferring glycosyl groups
Avi_5326	COG0753	catalase activity
Avi_5327	COG0306	phosphate transporter
Avi_5328	COG3842	ATPase activity
Avi_5329	COG1175	transmembrane transport
Avi_5330	COG0395	ABC-type sugar transport system, permease component
Avi_5337	COG3684	Belongs to the aldolase LacD family
Avi_5338	COG2390	Transcriptional regulator
Avi_5343	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5344	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Avi_5347	COG1725	Transcriptional regulator
Avi_5349	COG0747	negative chemotaxis
Avi_5352	COG0444	Belongs to the ABC transporter superfamily
Avi_5354	COG4608	Belongs to the ABC transporter superfamily
Avi_5355	COG0006	proline dipeptidase activity
Avi_5357	COG0747	negative chemotaxis
Avi_5360	COG0405	Gamma-glutamyltransferase
Avi_5363	COG0754	glutathionylspermidine amidase activity
Avi_5365	COG3766	membrane
Avi_5367	COG3789	protein conserved in bacteria
Avi_5371	COG0318	PFAM AMP-dependent synthetase and ligase
Avi_5373	COG1802	Transcriptional regulator
Avi_5375	COG0601	transmembrane transport
Avi_5381	COG0747	negative chemotaxis
Avi_5382	COG3706	GGDEF domain
Avi_5382	COG0745	RESPONSE REGULATOR receiver
Avi_5383	COG2205	protein histidine kinase activity
Avi_5384	COG2197	response regulator
Avi_5386	COG4585	Histidine kinase
Avi_5390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Avi_5391	COG4208	sulfate ABC transporter
Avi_5392	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Avi_5393	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Avi_5394	COG1609	Transcriptional regulator
Avi_5395	COG0673	inositol 2-dehydrogenase activity
Avi_5398	COG1653	transport
Avi_5400	COG0395	ABC-type sugar transport system, permease component
Avi_5401	COG3842	ATPase activity
Avi_5404	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Avi_5406	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_5409	COG0583	DNA-binding transcription factor activity
Avi_5410	COG0402	S-adenosylhomocysteine deaminase activity
Avi_5411	COG3250	beta-galactosidase activity
Avi_5412	COG1940	carbohydrate kinase activity
Avi_5413	COG2116	formate transmembrane transporter activity
Avi_5414	COG0402	S-adenosylhomocysteine deaminase activity
Avi_5424	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Avi_5425	COG0583	DNA-binding transcription factor activity
Avi_5431	COG0402	S-adenosylhomocysteine deaminase activity
Avi_5433	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Avi_5434	COG2080	2 iron, 2 sulfur cluster binding
Avi_5435	COG1012	belongs to the aldehyde dehydrogenase family
Avi_5438	COG2186	Transcriptional regulator
Avi_5439	COG1304	FMN binding
Avi_5441	COG0179	Fumarylacetoacetate (FAA) hydrolase
Avi_5448	COG0410	ABC transporter
Avi_5453	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Avi_5454	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Avi_5456	COG1126	abc transporter atp-binding protein
Avi_5457	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_5458	COG0765	amino acid transport
Avi_5459	COG0765	amino acid transport
Avi_5461	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Avi_5463	COG1764	response to oxidative stress
Avi_5467	COG1116	anion transmembrane transporter activity
Avi_5468	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_5469	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_5471	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_5472	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_5475	COG1959	2 iron, 2 sulfur cluster binding
Avi_5483	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_5490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_5494	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avi_5496	COG1116	anion transmembrane transporter activity
Avi_5501	COG4191	Histidine kinase
Avi_5502	COG4566	intracellular signal transduction
Avi_5504	COG3842	ATPase activity
Avi_5505	COG0395	ABC-type sugar transport system, permease component
Avi_5506	COG1175	transmembrane transport
Avi_5514	COG1940	carbohydrate kinase activity
Avi_5515	COG0747	negative chemotaxis
Avi_5516	COG0601	transmembrane transport
Avi_5517	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5520	COG4608	Belongs to the ABC transporter superfamily
Avi_5521	COG0745	RESPONSE REGULATOR receiver
Avi_5524	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Avi_5526	COG2076	Multidrug Resistance protein
Avi_5531	COG2076	Multidrug Resistance protein
Avi_5535	COG1215	transferase activity, transferring glycosyl groups
Avi_5539	COG3920	Histidine kinase
Avi_5539	COG2202	Pas domain
Avi_5541	COG0784	Response regulator, receiver
Avi_5544	COG1162	GTPase activity
Avi_5545	COG0784	Response regulator, receiver
Avi_5545	COG4191	Histidine kinase
Avi_5547	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avi_5548	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Avi_5548	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_5550	COG1126	abc transporter atp-binding protein
Avi_5552	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_5554	COG0840	transmembrane signaling receptor activity
Avi_5554	COG2972	Histidine kinase
Avi_5555	COG0835	chemotaxis
Avi_5557	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avi_5560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Avi_5562	COG0789	Transcriptional regulator
Avi_5563	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Avi_5564	COG0366	Alpha amylase catalytic
Avi_5565	COG0366	Alpha amylase catalytic
Avi_5566	COG1640	4-alpha-glucanotransferase
Avi_5568	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Avi_5570	COG0673	inositol 2-dehydrogenase activity
Avi_5575	COG1802	Transcriptional regulator
Avi_5576	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_5579	COG0673	inositol 2-dehydrogenase activity
Avi_5581	COG1175	transmembrane transport
Avi_5582	COG0395	ABC-type sugar transport system, permease component
Avi_5584	COG0673	inositol 2-dehydrogenase activity
Avi_5586	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Avi_5588	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5592	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Avi_5593	COG3920	Histidine kinase
Avi_5596	COG3685	Protein conserved in bacteria
Avi_5602	COG5001	Diguanylate cyclase
Avi_5606	COG1132	(ABC) transporter
Avi_5607	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Avi_5607	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avi_5610	COG3842	ATPase activity
Avi_5611	COG3833	ABC-type maltose transport systems, permease component
Avi_5624	COG0604	alcohol dehydrogenase
Avi_5624	COG3321	synthase
Avi_5628	COG1960	acyl-CoA dehydrogenase activity
Avi_5630	COG4608	Belongs to the ABC transporter superfamily
Avi_5633	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5634	COG0747	negative chemotaxis
Avi_5640	COG0583	DNA-binding transcription factor activity
Avi_5641	COG0747	negative chemotaxis
Avi_5643	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5648	COG0154	amidase activity
Avi_5651	COG1335	isochorismatase
Avi_5652	COG1129	ABC transporter
Avi_5655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Avi_5661	COG4172	Belongs to the ABC transporter superfamily
Avi_5662	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5663	COG0601	transmembrane transport
Avi_5671	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_5673	COG1012	belongs to the aldehyde dehydrogenase family
Avi_5675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Avi_5677	COG1309	transcriptional regulator
Avi_5680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Avi_5692	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5693	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Avi_5693	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Avi_5694	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Avi_5697	COG4172	Belongs to the ABC transporter superfamily
Avi_5698	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_5699	COG0601	transmembrane transport
Avi_5700	COG0747	negative chemotaxis
Avi_5701	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_5703	COG2186	Transcriptional regulator
Avi_5708	COG3842	ATPase activity
Avi_5709	COG1175	transmembrane transport
Avi_5710	COG0395	ABC-type sugar transport system, permease component
Avi_5713	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Avi_5718	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_5719	COG1012	belongs to the aldehyde dehydrogenase family
Avi_5720	COG2084	Dehydrogenase
Avi_5723	COG3386	PFAM SMP-30 Gluconolaconase
Avi_5725	COG2771	luxR family
Avi_5726	COG0019	diaminopimelate decarboxylase activity
Avi_5730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Avi_5738	COG1175	transmembrane transport
Avi_5739	COG0395	ABC-type sugar transport system, permease component
Avi_5744	COG0446	pyridine nucleotide-disulphide oxidoreductase
Avi_5744	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Avi_5745	COG4311	Sarcosine oxidase, delta subunit
Avi_5746	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_5747	COG4977	sequence-specific DNA binding
Avi_5749	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Avi_5750	COG2218	PFAM glutamate synthase alpha subunit domain protein
Avi_5751	COG0069	glutamate synthase activity
Avi_5754	COG1304	FMN binding
Avi_5758	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Avi_5760	COG3842	ATPase activity
Avi_5762	COG1175	transmembrane transport
Avi_5763	COG0395	ABC-type sugar transport system, permease component
Avi_5764	COG1609	Transcriptional regulator
Avi_5769	COG0412	Dienelactone hydrolase
Avi_5771	COG0583	DNA-binding transcription factor activity
Avi_5774	COG0583	DNA-binding transcription factor activity
Avi_5782	COG0306	phosphate transporter
Avi_5786	COG0277	FAD linked oxidase domain protein
Avi_5788	COG0277	FAD linked oxidase domain protein
Avi_5789	COG0247	lactate metabolic process
Avi_5791	COG0625	glutathione transferase activity
Avi_5794	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Avi_5795	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Avi_5801	COG0124	histidyl-tRNA synthetase
Avi_5808	COG2818	Glycosylase
Avi_5810	COG1376	ErfK ybiS ycfS ynhG family protein
Avi_5810	COG1388	LysM domain
Avi_5811	COG1376	ErfK ybiS ycfS ynhG family protein
Avi_5812	COG2909	trisaccharide binding
Avi_5814	COG2137	regulation of response to DNA damage stimulus
Avi_5815	COG2130	NADP-dependent
Avi_5819	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Avi_5823	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_5826	COG0196	riboflavin kinase activity
Avi_5828	COG2059	Chromate
Avi_5829	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Avi_5830	COG0459	protein refolding
Avi_5835	COG3842	ATPase activity
Avi_5839	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_5840	COG1177	transmembrane transport
Avi_5841	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Avi_5843	COG0019	diaminopimelate decarboxylase activity
Avi_5845	COG4770	biotin carboxylase activity
Avi_5847	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Avi_5849	COG4336	lyase activity
Avi_5851	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Avi_5852	COG1914	H( )-stimulated, divalent metal cation uptake system
Avi_5853	COG1802	Transcriptional regulator
Avi_5854	COG1522	sequence-specific DNA binding
Avi_5856	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Avi_5863	COG0583	DNA-binding transcription factor activity
Avi_5865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Avi_5866	COG0511	ligase activity, forming carbon-carbon bonds
Avi_5868	COG0439	Biotin carboxylase
Avi_5870	COG1984	allophanate hydrolase subunit 2
Avi_5873	COG3842	ATPase activity
Avi_5874	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_5877	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5878	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_5881	COG3842	ATPase activity
Avi_5882	COG0726	polysaccharide deacetylase
Avi_5884	COG0523	cobalamin synthesis protein
Avi_5887	COG1522	sequence-specific DNA binding
Avi_5890	COG0659	secondary active sulfate transmembrane transporter activity
Avi_5892	COG0243	molybdopterin cofactor binding
Avi_5894	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Avi_5895	COG1116	anion transmembrane transporter activity
Avi_5896	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_5897	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_5899	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_5900	COG3707	response regulator
Avi_5907	COG0583	DNA-binding transcription factor activity
Avi_5908	COG1960	acyl-CoA dehydrogenase activity
Avi_5909	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Avi_5914	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Avi_5917	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Avi_5920	COG2022	thiamine diphosphate biosynthetic process
Avi_5923	COG0469	pyruvate kinase activity
Avi_5924	COG3206	protein involved in exopolysaccharide biosynthesis
Avi_5924	COG0489	protein tyrosine kinase activity
Avi_5925	COG1215	transferase activity, transferring glycosyl groups
Avi_5926	COG1215	transferase activity, transferring glycosyl groups
Avi_5927	COG1215	transferase activity, transferring glycosyl groups
Avi_5928	COG0438	transferase activity, transferring glycosyl groups
Avi_5929	COG2273	Hydrolase Family 16
Avi_5930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Avi_5931	COG2244	polysaccharide biosynthetic process
Avi_5932	COG0463	Glycosyl transferase, family 2
Avi_5933	COG2327	Polysaccharide pyruvyl transferase
Avi_5934	COG1215	transferase activity, transferring glycosyl groups
Avi_5936	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Avi_5937	COG1596	polysaccharide export
Avi_5938	COG3307	-O-antigen
Avi_5943	COG0400	carboxylic ester hydrolase activity
Avi_5945	COG0346	lactoylglutathione lyase activity
Avi_5946	COG0583	DNA-binding transcription factor activity
Avi_5952	COG1289	transmembrane transporter activity
Avi_5956	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Avi_5958	COG2986	histidine ammonia-lyase
Avi_5959	COG1228	amidohydrolase
Avi_5960	COG0402	S-adenosylhomocysteine deaminase activity
Avi_5964	COG4598	ABC transporter
Avi_5965	COG0765	amino acid transport
Avi_5966	COG0765	amino acid transport
Avi_5967	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_5968	COG1072	(Pantothenic acid kinase))
Avi_5972	COG1940	carbohydrate kinase activity
Avi_5981	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
Avi_5983	COG0848	biopolymer transport protein
Avi_5989	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avi_6000	COG0784	Response regulator, receiver
Avi_6007	COG1793	dna ligase
Avi_6010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Avi_6012	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Avi_6015	COG0438	transferase activity, transferring glycosyl groups
Avi_6021	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Avi_6023	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Avi_6025	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Avi_6026	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Avi_6028	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avi_6029	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_6031	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Avi_6064	COG0640	Transcriptional regulator
Avi_6065	COG0798	PFAM Bile acid sodium symporter
Avi_6066	COG1393	Belongs to the ArsC family
Avi_6068	COG0431	NADPH-dependent FMN reductase
Avi_6070	COG0745	RESPONSE REGULATOR receiver
Avi_6071	COG2205	protein histidine kinase activity
Avi_6072	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Avi_6074	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Avi_6079	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_6080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Avi_6081	COG1522	sequence-specific DNA binding
Avi_6084	COG2267	carboxylic ester hydrolase activity
Avi_6087	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_6088	COG1012	belongs to the aldehyde dehydrogenase family
Avi_6090	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_6091	COG1177	transmembrane transport
Avi_6092	COG3842	ATPase activity
Avi_6093	COG1012	belongs to the aldehyde dehydrogenase family
Avi_6095	COG4154	Belongs to the RbsD FucU family
Avi_6097	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_6098	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_6099	COG1129	ABC transporter
Avi_6100	COG1879	ABC-type sugar transport system periplasmic component
Avi_6103	COG2721	sulfolactate sulfo-lyase activity
Avi_6105	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_6107	COG2205	protein histidine kinase activity
Avi_6108	COG0745	RESPONSE REGULATOR receiver
Avi_6117	COG0183	Belongs to the thiolase family
Avi_6118	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Avi_6121	COG1414	Transcriptional regulator
Avi_6124	COG0583	DNA-binding transcription factor activity
Avi_6126	COG2267	carboxylic ester hydrolase activity
Avi_6127	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Avi_6128	COG3485	protocatechuate 3,4-dioxygenase
Avi_6129	COG3485	protocatechuate 3,4-dioxygenase
Avi_6130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Avi_6131	COG0604	alcohol dehydrogenase
Avi_6133	COG1674	ftsk spoiiie
Avi_6134	COG3842	ATPase activity
Avi_6137	COG0668	transmembrane transport
Avi_6143	COG5265	(ABC) transporter
Avi_6144	COG2205	protein histidine kinase activity
Avi_6145	COG0745	RESPONSE REGULATOR receiver
Avi_6154	COG0592	DNA-directed DNA polymerase activity
Avi_6173	COG1674	ftsk spoiiie
Avi_6185	COG0740	serine-type endopeptidase activity
Avi_6212	COG3346	SURF1 family
Avi_6213	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Avi_6214	COG1845	cytochrome c oxidase, subunit III
Avi_6215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Avi_6218	COG1595	DNA-templated transcription, initiation
Avi_6220	COG0670	Belongs to the BI1 family
Avi_6224	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Avi_6224	COG2273	Hydrolase Family 16
Avi_6225	COG1301	dicarboxylic acid transport
Avi_6227	COG4191	Histidine kinase
Avi_6228	COG2204	response regulator
Avi_6229	COG1309	transcriptional regulator
Avi_6233	COG1940	carbohydrate kinase activity
Avi_6234	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Avi_6235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Avi_6239	COG0395	ABC-type sugar transport system, permease component
Avi_6242	COG3842	ATPase activity
Avi_6250	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_6253	COG2814	Major facilitator Superfamily
Avi_6254	COG3142	Participates in the control of copper homeostasis
Avi_6255	COG1607	acyl-coa hydrolase
Avi_6258	COG0642	Histidine kinase
Avi_6259	COG0745	RESPONSE REGULATOR receiver
Avi_6263	COG4952	isomerase
Avi_6264	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_6264	COG3347	Dehydrogenase
Avi_6267	COG1129	ABC transporter
Avi_6268	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_6270	COG3254	rhamnose metabolic process
Avi_6272	COG0179	Fumarylacetoacetate (FAA) hydrolase
Avi_6277	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_6279	COG3842	ATPase activity
Avi_6283	COG2094	Belongs to the DNA glycosylase MPG family
Avi_6284	COG1136	(ABC) transporter
Avi_6287	COG4303	Ethanolamine ammonia lyase large subunit
Avi_6288	COG4302	ethanolamine ammonia-lyase activity
Avi_7000	COG1192	Involved in chromosome partitioning
Avi_7001	COG1475	DNA binding
Avi_7002	COG0640	Transcriptional regulator
Avi_7004	COG2072	flavoprotein involved in K transport
Avi_7005	COG0745	RESPONSE REGULATOR receiver
Avi_7005	COG3706	GGDEF domain
Avi_7022	COG3938	Belongs to the proline racemase family
Avi_7026	COG4608	Belongs to the ABC transporter superfamily
Avi_7028	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7029	COG0601	transmembrane transport
Avi_7035	COG1475	DNA binding
Avi_7039	COG0300	oxidoreductase activity
Avi_7042	COG0776	regulation of translation
Avi_7044	COG3436	PFAM IS66 Orf2 family protein
Avi_7045	COG4372	Transposase
Avi_7047	COG3831	ATPase activity
Avi_7056	COG3501	Rhs element vgr protein
Avi_7073	COG1396	sequence-specific DNA binding
Avi_7077	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Avi_7079	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Avi_7081	COG3181	Tripartite tricarboxylate transporter family receptor
Avi_7084	COG1304	FMN binding
Avi_7090	COG0559	Belongs to the binding-protein-dependent transport system permease family
Avi_7092	COG0154	amidase activity
Avi_7093	COG3293	Transposase
Avi_7098	COG1280	lysine exporter protein (LysE YggA)
Avi_7106	COG3848	Pyruvate phosphate dikinase
Avi_7106	COG0574	Belongs to the PEP-utilizing enzyme family
Avi_7108	COG0574	Belongs to the PEP-utilizing enzyme family
Avi_7108	COG3848	Pyruvate phosphate dikinase
Avi_7109	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Avi_7110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Avi_7114	COG3316	Transposase and inactivated derivatives
Avi_7121	COG0583	DNA-binding transcription factor activity
Avi_7122	COG2814	Major facilitator Superfamily
Avi_7125	COG1335	isochorismatase
Avi_7126	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_7127	COG0154	amidase activity
Avi_7128	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Avi_7130	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_7131	COG3833	ABC-type maltose transport systems, permease component
Avi_7132	COG3842	ATPase activity
Avi_7136	COG3609	addiction module antidote protein, CC2985 family
Avi_7150	COG2226	methyltransferase
Avi_7154	COG3316	Transposase and inactivated derivatives
Avi_7157	COG0559	Belongs to the binding-protein-dependent transport system permease family
Avi_7163	COG4521	taurine ABC transporter
Avi_7165	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Avi_7166	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_7167	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_7173	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7174	COG0601	transmembrane transport
Avi_7175	COG0747	negative chemotaxis
Avi_7179	COG1960	acyl-CoA dehydrogenase activity
Avi_7181	COG0747	negative chemotaxis
Avi_7185	COG0444	Belongs to the ABC transporter superfamily
Avi_7188	COG0667	Aldo Keto reductase
Avi_7190	COG0778	Nitroreductase
Avi_7191	COG4172	Belongs to the ABC transporter superfamily
Avi_7192	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7194	COG0747	negative chemotaxis
Avi_7196	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_7197	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_7198	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Avi_7200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_7206	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_7212	COG0747	negative chemotaxis
Avi_7214	COG0747	negative chemotaxis
Avi_7215	COG1473	amidohydrolase
Avi_7216	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Avi_7221	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Avi_7224	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_7225	COG0765	amino acid transport
Avi_7227	COG1126	abc transporter atp-binding protein
Avi_7231	COG2011	ABC-type metal ion transport system permease component
Avi_7234	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Avi_7235	COG2011	ABC-type metal ion transport system permease component
Avi_7245	COG0400	carboxylic ester hydrolase activity
Avi_7251	COG3938	Belongs to the proline racemase family
Avi_7252	COG4176	ABC-type proline glycine betaine transport system permease component
Avi_7253	COG4176	ABC-type proline glycine betaine transport system permease component
Avi_7254	COG3448	diguanylate cyclase activity
Avi_7254	COG4175	Glycine betaine
Avi_7256	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_7257	COG1012	belongs to the aldehyde dehydrogenase family
Avi_7258	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Avi_7259	COG2186	Transcriptional regulator
Avi_7262	COG1802	Transcriptional regulator
Avi_7267	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Avi_7268	COG1349	DNA-binding transcription factor activity
Avi_7269	COG4608	Belongs to the ABC transporter superfamily
Avi_7270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7271	COG0601	transmembrane transport
Avi_7287	COG1120	ATPase activity
Avi_7289	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avi_7290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avi_7292	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Avi_7293	COG1629	transport
Avi_7293	COG4774	siderophore transport
Avi_7304	COG2226	methyltransferase
Avi_7308	COG0318	PFAM AMP-dependent synthetase and ligase
Avi_7312	COG0534	Mate efflux family protein
Avi_7320	COG0840	transmembrane signaling receptor activity
Avi_7322	COG1446	asparaginase
Avi_7323	COG2362	D-Aminopeptidase
Avi_7325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7328	COG0747	negative chemotaxis
Avi_7329	COG4172	Belongs to the ABC transporter superfamily
Avi_7333	COG1940	carbohydrate kinase activity
Avi_7335	COG0395	ABC-type sugar transport system, permease component
Avi_7336	COG1175	transmembrane transport
Avi_7339	COG0110	maltose O-acetyltransferase activity
Avi_7343	COG3842	ATPase activity
Avi_7346	COG0395	ABC-type sugar transport system, permease component
Avi_7347	COG1175	transmembrane transport
Avi_7351	COG2186	Transcriptional regulator
Avi_7355	COG3842	ATPase activity
Avi_7358	COG0395	ABC-type sugar transport system, permease component
Avi_7361	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avi_7365	COG1129	ABC transporter
Avi_7366	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_7367	COG1737	Transcriptional regulator
Avi_7371	COG1064	alcohol dehydrogenase
Avi_7373	COG3177	Filamentation induced by cAMP protein fic
Avi_7374	COG1069	ribulokinase activity
Avi_7376	COG4214	carbohydrate transport
Avi_7381	COG2814	Major facilitator Superfamily
Avi_7386	COG1780	Probably involved in ribonucleotide reductase function
Avi_7388	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Avi_7389	COG0640	Transcriptional regulator
Avi_7390	COG1902	pentaerythritol trinitrate reductase activity
Avi_7392	COG0154	amidase activity
Avi_7396	COG0583	DNA-binding transcription factor activity
Avi_7398	COG2423	ornithine cyclodeaminase activity
Avi_7400	COG0251	oxidation-reduction process
Avi_7402	COG1414	Transcriptional regulator
Avi_7405	COG1960	acyl-CoA dehydrogenase activity
Avi_7409	COG1414	Transcriptional regulator
Avi_7413	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Avi_7416	COG2271	Major facilitator Superfamily
Avi_7417	COG1960	acyl-CoA dehydrogenase activity
Avi_7421	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_7423	COG0179	Fumarylacetoacetate (FAA) hydrolase
Avi_7425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_7430	COG0179	Fumarylacetoacetate (FAA) hydrolase
Avi_7443	COG3485	protocatechuate 3,4-dioxygenase
Avi_7452	COG1177	transmembrane transport
Avi_7453	COG3842	ATPase activity
Avi_7454	COG1940	carbohydrate kinase activity
Avi_7457	COG0673	inositol 2-dehydrogenase activity
Avi_7466	COG1573	uracil-dna glycosylase
Avi_7472	COG1609	Transcriptional regulator
Avi_7476	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_7477	COG1735	metal-dependent hydrolase with the TIM-barrel fold
Avi_7488	COG0745	RESPONSE REGULATOR receiver
Avi_7490	COG2205	protein histidine kinase activity
Avi_7497	COG0583	DNA-binding transcription factor activity
Avi_7500	COG3316	Transposase and inactivated derivatives
Avi_7502	COG0697	spore germination
Avi_7504	COG2801	Transposase and inactivated derivatives
Avi_7508	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_7510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Avi_7513	COG1522	sequence-specific DNA binding
Avi_7515	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Avi_7517	COG0601	transmembrane transport
Avi_7518	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7520	COG0444	Belongs to the ABC transporter superfamily
Avi_7522	COG4608	Belongs to the ABC transporter superfamily
Avi_7528	COG0163	prenyltransferase activity
Avi_7538	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Avi_7540	COG2986	histidine ammonia-lyase
Avi_7544	COG3552	Protein containing von Willebrand factor type A (VWA) domain
Avi_7548	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Avi_7549	COG0714	Associated with various cellular activities
Avi_7550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Avi_7557	COG3501	Rhs element vgr protein
Avi_7566	COG2826	transposase and inactivated derivatives, IS30 family
Avi_7571	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Avi_7573	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Avi_7577	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Avi_7579	COG2144	transferase activity, transferring acyl groups
Avi_7580	COG0438	transferase activity, transferring glycosyl groups
Avi_7583	COG2072	flavoprotein involved in K transport
Avi_7586	COG0243	molybdopterin cofactor binding
Avi_7591	COG0395	ABC-type sugar transport system, permease component
Avi_7595	COG1309	transcriptional regulator
Avi_7599	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Avi_7602	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_7603	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Avi_7611	COG2186	Transcriptional regulator
Avi_7613	COG0747	negative chemotaxis
Avi_7614	COG0601	transmembrane transport
Avi_7616	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Avi_7621	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Avi_7623	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Avi_7625	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Avi_7627	COG1999	signal sequence binding
Avi_7629	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Avi_7633	COG0243	molybdopterin cofactor binding
Avi_7634	COG0662	Cupin 2, conserved barrel domain protein
Avi_7634	COG2207	Transcriptional regulator
Avi_7637	COG1960	acyl-CoA dehydrogenase activity
Avi_7648	COG3284	Transcriptional regulator
Avi_7649	COG1063	alcohol dehydrogenase
Avi_7652	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Avi_7654	COG0511	ligase activity, forming carbon-carbon bonds
Avi_7655	COG0439	Biotin carboxylase
Avi_7658	COG1984	allophanate hydrolase subunit 2
Avi_7659	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Avi_7662	COG4221	oxidoreductase activity
Avi_7663	COG0765	amino acid transport
Avi_7664	COG0765	amino acid transport
Avi_7667	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Avi_7669	COG3293	Transposase
Avi_7675	COG0247	lactate metabolic process
Avi_7675	COG2181	nitrate reductase activity
Avi_7676	COG0277	FAD linked oxidase domain protein
Avi_7683	COG2124	cytochrome p450
Avi_7687	COG0318	PFAM AMP-dependent synthetase and ligase
Avi_7689	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Avi_7690	COG1024	Enoyl-CoA hydratase
Avi_7694	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Avi_7698	COG3547	Transposase (IS116 IS110 IS902 family)
Avi_7700	COG2801	Transposase and inactivated derivatives
Avi_8000	COG1192	Involved in chromosome partitioning
Avi_8001	COG1475	DNA binding
Avi_8002	COG0640	Transcriptional regulator
Avi_8008	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Avi_8014	COG4297	protein containing double-stranded beta helix domain
Avi_8018	COG3335	DDE superfamily endonuclease
Avi_8032	COG0419	ATPase involved in DNA repair
Avi_8035	COG4644	lycopene metabolic process
Avi_8067	COG1396	sequence-specific DNA binding
Avi_8068	COG5001	Diguanylate cyclase
Avi_8068	COG3300	MHYT domain
Avi_8070	COG3316	Transposase and inactivated derivatives
Avi_8079	COG2890	protein-(glutamine-N5) methyltransferase activity
Avi_8080	COG3335	DDE superfamily endonuclease
Avi_8089	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Avi_8103	COG3547	Transposase (IS116 IS110 IS902 family)
Avi_8104	COG3335	DDE superfamily endonuclease
Avi_8105	COG3547	Transposase (IS116 IS110 IS902 family)
Avi_8114	COG4974	Belongs to the 'phage' integrase family
Avi_8115	COG0582	viral genome integration into host DNA
Avi_8116	COG0582	viral genome integration into host DNA
Avi_8120	COG5489	Protein of unknown function (DUF736)
Avi_8121	COG5489	Protein of unknown function (DUF736)
Avi_8123	COG0776	regulation of translation
Avi_8126	COG3831	ATPase activity
Avi_8142	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Avi_8143	COG1522	sequence-specific DNA binding
Avi_8147	COG3842	ATPase activity
Avi_8148	COG1177	transmembrane transport
Avi_8149	COG1177	transmembrane transport
Avi_8152	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_8156	COG1177	transmembrane transport
Avi_8157	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Avi_8158	COG3842	ATPase activity
Avi_8162	COG0747	negative chemotaxis
Avi_8165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Avi_8171	COG1176	ABC-type spermidine putrescine transport system, permease component I
Avi_8173	COG1840	ABC-type Fe3 transport system, periplasmic component
Avi_8180	COG0601	transmembrane transport
Avi_8183	COG4172	Belongs to the ABC transporter superfamily
Avi_8187	COG1064	alcohol dehydrogenase
Avi_8198	COG1192	Involved in chromosome partitioning
Avi_8214	COG1192	Involved in chromosome partitioning
Avi_8217	COG0745	RESPONSE REGULATOR receiver
Avi_8231	COG4372	Transposase
Avi_8249	COG4372	Transposase
Avi_8253	COG4974	Belongs to the 'phage' integrase family
Avi_8254	COG0582	viral genome integration into host DNA
Avi_8256	COG3344	reverse transcriptase
Avi_8258	COG3335	DDE superfamily endonuclease
Avi_8259	COG0582	viral genome integration into host DNA
Avi_8260	COG4974	Belongs to the 'phage' integrase family
Avi_8264	COG3344	reverse transcriptase
Avi_8282	COG3328	transposase activity
Avi_8291	COG3335	DDE superfamily endonuclease
Avi_8304	COG4149	molybdate abc transporter
Avi_8305	COG1177	transmembrane transport
Avi_8306	COG3842	ATPase activity
Avi_8307	COG1840	ABC-type Fe3 transport system, periplasmic component
Avi_8310	COG4172	Belongs to the ABC transporter superfamily
Avi_8312	COG0601	transmembrane transport
Avi_8313	COG4166	transmembrane transport
Avi_8326	COG3701	Conjugal transfer protein
Avi_8328	COG3846	protein secretion by the type IV secretion system
Avi_8330	COG5314	conjugation
Avi_8331	COG3451	type IV secretory pathway VirB4
Avi_8334	COG4962	Type ii secretion system protein e
Avi_9001	COG1192	Involved in chromosome partitioning
Avi_9002	COG1475	DNA binding
Avi_9003	COG1414	Transcriptional regulator
Avi_9004	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Avi_9010	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Avi_9026	COG3920	Histidine kinase
Avi_9028	COG4191	Histidine kinase
Avi_9028	COG0784	Response regulator, receiver
Avi_9041	COG0784	Response regulator, receiver
Avi_9041	COG4191	Histidine kinase
Avi_9047	COG0784	Response regulator, receiver
Avi_9047	COG4191	Histidine kinase
Avi_9065	COG0840	transmembrane signaling receptor activity
Avi_9076	COG0840	transmembrane signaling receptor activity
Avi_9083	COG4251	negative regulation of phosphorylation
Avi_9088	COG2972	Histidine kinase
Avi_9088	COG0840	transmembrane signaling receptor activity
Avi_9096	COG3436	PFAM IS66 Orf2 family protein
Avi_9098	COG5002	protein histidine kinase activity
Avi_9100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Avi_9103	COG2205	protein histidine kinase activity
Avi_9103	COG3437	response regulator, receiver
Avi_9103	COG3850	Histidine kinase
Avi_9103	COG4999	Histidine kinase
Avi_9109	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Avi_9115	COG3293	Transposase
Avi_9123	COG3265	gluconokinase activity
Avi_9124	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_9125	COG1129	ABC transporter
Avi_9126	COG1172	Belongs to the binding-protein-dependent transport system permease family
Avi_9130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Avi_9131	COG1609	Transcriptional regulator
Avi_9134	COG3547	Transposase (IS116 IS110 IS902 family)
Avi_9143	COG0601	transmembrane transport
Avi_9145	COG2188	Transcriptional regulator
Avi_9146	COG2222	sugar isomerase
Avi_9147	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Avi_9149	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
Avi_9150	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
Avi_9152	COG0436	Aminotransferase
Avi_9155	COG0587	DNA-directed DNA polymerase activity
Avi_9165	COG1475	DNA binding
Avi_9175	COG5489	Protein of unknown function (DUF736)
Avi_9197	COG3842	ATPase activity
Avi_9198	COG3833	ABC-type maltose transport systems, permease component
Avi_9200	COG1653	transport
Avi_9206	COG1028	Short-chain dehydrogenase reductase Sdr
Avi_9211	COG3547	Transposase (IS116 IS110 IS902 family)
Avi_9216	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Avi_9217	COG1129	ABC transporter
Avi_9217	COG0842	Transport permease protein
Avi_9218	COG0842	Transport permease protein
Avi_9219	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Avi_9220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Avi_9221	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Avi_9222	COG1012	belongs to the aldehyde dehydrogenase family
Avi_9228	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_9229	COG1309	transcriptional regulator
Avi_9230	COG2267	carboxylic ester hydrolase activity
Avi_9233	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Avi_9239	COG0765	amino acid transport
Avi_9240	COG0765	amino acid transport
Avi_9247	COG2086	electron transfer activity
Avi_9260	COG3701	Conjugal transfer protein
Avi_9261	COG3846	protein secretion by the type IV secretion system
Avi_9263	COG5314	conjugation
Avi_9265	COG3451	type IV secretory pathway VirB4
Avi_9269	COG4962	Type ii secretion system protein e
Avi_9501	COG1192	Involved in chromosome partitioning
Avi_9502	COG1475	DNA binding
Avi_9503	COG0640	Transcriptional regulator
Avi_9505	COG3706	GGDEF domain
Avi_9510	COG4974	Belongs to the 'phage' integrase family
Avi_9516	COG0052	Belongs to the universal ribosomal protein uS2 family
Avi_9533	COG1396	sequence-specific DNA binding
Avi_9546	COG1278	Cold shock
Avi_9572	COG5489	Protein of unknown function (DUF736)
Avi_9580	COG5489	Protein of unknown function (DUF736)
Avi_9587	COG3831	ATPase activity
Avi_9595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Avi_9596	COG4959	Type IV secretory pathway protease TraF
Avi_9607	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Avi_9610	COG1132	(ABC) transporter
Avi_9620	COG2963	transposase activity
Avi_9623	COG4372	Transposase
Avi_9634	COG0066	3-isopropylmalate dehydratase activity
Avi_9636	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Avi_9643	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Avi_9651	COG3701	Conjugal transfer protein
Avi_9653	COG3846	protein secretion by the type IV secretion system
Avi_9655	COG5314	conjugation
Avi_9656	COG3451	type IV secretory pathway VirB4
Avi_9658	COG5268	conjugation
Avi_9659	COG3838	Conjugal transfer protein Trbc
Avi_9661	COG4962	Type ii secretion system protein e
Avi_9665	COG2197	response regulator
Avi_9666	COG3916	Acyl-homoserine-lactone synthase
Avi_9800	COG1192	Involved in chromosome partitioning
Avi_9801	COG1475	DNA binding
Avi_9802	COG0640	Transcriptional regulator
Avi_9811	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
Avi_9819	COG0741	lytic transglycosylase activity
Avi_9821	COG3451	type IV secretory pathway VirB4
Avi_9822	COG3838	Conjugal transfer protein Trbc
Avi_9824	COG0741	lytic transglycosylase activity
Avi_9833	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Avi_9835	COG2390	Transcriptional regulator
Avi_9835	COG4584	PFAM Integrase catalytic
Avi_9836	COG1484	DNA-dependent DNA replication
Avi_9863	COG0789	Transcriptional regulator
Avi_9869	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Avi_9896	COG1475	DNA binding
Avi_9907	COG2184	nucleotidyltransferase activity
Avi_9909	COG4227	nucleotidyltransferase activity