locus-tag	class	description
RvVAT039_00010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RvVAT039_00050	COG3665	Urea carboxylase-associated protein
RvVAT039_00070	COG4770	biotin carboxylase activity
RvVAT039_00110	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RvVAT039_00120	COG2153	protein acetylation
RvVAT039_00130	COG1671	Belongs to the UPF0178 family
RvVAT039_00150	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RvVAT039_00160	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_00180	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_00190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RvVAT039_00200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_00210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RvVAT039_00220	COG0750	zinc metalloprotease
RvVAT039_00240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RvVAT039_00250	COG0233	cytoplasmic translational termination
RvVAT039_00260	COG0528	UMP kinase activity
RvVAT039_00270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RvVAT039_00290	COG0052	Belongs to the universal ribosomal protein uS2 family
RvVAT039_00340	COG0537	adenosine 5'-monophosphoramidase activity
RvVAT039_00380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RvVAT039_00430	COG2267	carboxylic ester hydrolase activity
RvVAT039_00480	COG0626	cystathionine gamma-synthase activity
RvVAT039_00490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_00500	COG4597	amino acid ABC transporter
RvVAT039_00510	COG0765	amino acid transport
RvVAT039_00520	COG1126	abc transporter atp-binding protein
RvVAT039_00530	COG0154	amidase activity
RvVAT039_00540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RvVAT039_00550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RvVAT039_00570	COG2313	pseudouridylate synthase activity
RvVAT039_00580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RvVAT039_00590	COG2333	competence protein COMEC
RvVAT039_00590	COG0658	competence protein
RvVAT039_00600	COG0372	Belongs to the citrate synthase family
RvVAT039_00620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RvVAT039_00630	COG0134	indole-3-glycerol-phosphate synthase activity
RvVAT039_00640	COG0315	cyclic pyranopterin monophosphate synthase activity
RvVAT039_00650	COG0303	'Molybdopterin
RvVAT039_00660	COG0671	phosphoesterase, PA-phosphatase related
RvVAT039_00670	COG1492	cobalamin metabolic process
RvVAT039_00690	COG4176	ABC-type proline glycine betaine transport system permease component
RvVAT039_00700	COG0517	IMP dehydrogenase activity
RvVAT039_00700	COG4175	Glycine betaine
RvVAT039_00740	COG3698	Phosphodiester glycosidase
RvVAT039_00790	COG0583	DNA-binding transcription factor activity
RvVAT039_00850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_00900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RvVAT039_00910	COG0840	transmembrane signaling receptor activity
RvVAT039_00930	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RvVAT039_00950	COG1058	Belongs to the CinA family
RvVAT039_00950	COG1546	Belongs to the CinA family
RvVAT039_00960	COG2972	Histidine kinase
RvVAT039_00960	COG0840	transmembrane signaling receptor activity
RvVAT039_00970	COG0835	chemotaxis
RvVAT039_00990	COG1760	l-serine dehydratase
RvVAT039_01040	COG2239	Acts as a magnesium transporter
RvVAT039_01090	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RvVAT039_01100	COG2099	Precorrin-6x reductase
RvVAT039_01110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RvVAT039_01140	COG2875	Belongs to the precorrin methyltransferase family
RvVAT039_01190	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RvVAT039_01310	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RvVAT039_01360	COG1862	Preprotein translocase
RvVAT039_01390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RvVAT039_01400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RvVAT039_01410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RvVAT039_01420	COG0805	protein transport
RvVAT039_01430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RvVAT039_01440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RvVAT039_01450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RvVAT039_01460	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RvVAT039_01470	COG1472	Belongs to the glycosyl hydrolase 3 family
RvVAT039_01500	COG0018	arginyl-trna synthetase
RvVAT039_01510	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RvVAT039_01520	COG0316	Belongs to the HesB IscA family
RvVAT039_01560	COG0525	valine-tRNA ligase activity
RvVAT039_01590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RvVAT039_01660	COG0584	glycerophosphoryl diester phosphodiesterase
RvVAT039_01670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_01750	COG0583	DNA-binding transcription factor activity
RvVAT039_01770	COG3842	ATPase activity
RvVAT039_01780	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_01790	COG1177	transmembrane transport
RvVAT039_01830	COG0251	oxidation-reduction process
RvVAT039_01890	COG0842	Transport permease protein
RvVAT039_01900	COG1131	(ABC) transporter
RvVAT039_01920	COG0745	RESPONSE REGULATOR receiver
RvVAT039_01950	COG2226	methyltransferase
RvVAT039_01960	COG3264	Mechanosensitive ion channel
RvVAT039_01960	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RvVAT039_01990	COG4558	Periplasmic binding protein
RvVAT039_02000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_02010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RvVAT039_02330	COG3750	Belongs to the UPF0335 family
RvVAT039_02580	COG0384	phenazine biosynthesis protein PhzF
RvVAT039_02630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RvVAT039_02650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RvVAT039_02680	COG1522	sequence-specific DNA binding
RvVAT039_02690	COG1794	racemase activity, acting on amino acids and derivatives
RvVAT039_02700	COG1309	transcriptional regulator
RvVAT039_02710	COG2814	Major facilitator Superfamily
RvVAT039_02730	COG1733	regulation of RNA biosynthetic process
RvVAT039_02750	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RvVAT039_02770	COG0789	Transcriptional regulator
RvVAT039_02780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RvVAT039_02810	COG0656	L-ascorbic acid biosynthetic process
RvVAT039_02840	COG0028	Belongs to the TPP enzyme family
RvVAT039_02880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RvVAT039_02890	COG0560	Phosphoserine phosphatase
RvVAT039_02920	COG0330	HflC and HflK could
RvVAT039_02950	COG2259	Doxx family
RvVAT039_02960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RvVAT039_03020	COG0277	FAD linked oxidase domain protein
RvVAT039_03030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RvVAT039_03040	COG0581	inorganic phosphate transmembrane transporter activity
RvVAT039_03050	COG0573	inorganic phosphate transmembrane transporter activity
RvVAT039_03060	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RvVAT039_03120	COG4993	Dehydrogenase
RvVAT039_03130	COG1335	isochorismatase
RvVAT039_03140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RvVAT039_03150	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RvVAT039_03170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RvVAT039_03240	COG2264	protein methyltransferase activity
RvVAT039_03250	COG1999	signal sequence binding
RvVAT039_03260	COG0840	transmembrane signaling receptor activity
RvVAT039_03270	COG0835	chemotaxis
RvVAT039_03300	COG2176	DNA-directed DNA polymerase activity
RvVAT039_03310	COG0840	transmembrane signaling receptor activity
RvVAT039_03320	COG0456	acetyltransferase
RvVAT039_03380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RvVAT039_03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RvVAT039_03420	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RvVAT039_03440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RvVAT039_03450	COG0849	cell division
RvVAT039_03460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RvVAT039_03470	COG1181	Belongs to the D-alanine--D-alanine ligase family
RvVAT039_03490	COG0477	Major facilitator Superfamily
RvVAT039_03500	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RvVAT039_03510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RvVAT039_03520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RvVAT039_03540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RvVAT039_03550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RvVAT039_03570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RvVAT039_03600	COG0275	rRNA processing
RvVAT039_03610	COG2001	Belongs to the MraZ family
RvVAT039_03640	COG3023	N-Acetylmuramoyl-L-alanine amidase
RvVAT039_03770	COG2226	methyltransferase
RvVAT039_03780	COG0840	transmembrane signaling receptor activity
RvVAT039_03790	COG2972	Histidine kinase
RvVAT039_03790	COG0840	transmembrane signaling receptor activity
RvVAT039_03820	COG2267	carboxylic ester hydrolase activity
RvVAT039_03830	COG0697	spore germination
RvVAT039_03840	COG0028	Belongs to the TPP enzyme family
RvVAT039_03860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RvVAT039_03870	COG0251	oxidation-reduction process
RvVAT039_03900	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_03950	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RvVAT039_03960	COG4149	molybdate abc transporter
RvVAT039_03970	COG3842	ATPase activity
RvVAT039_04000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_04010	COG2197	response regulator
RvVAT039_04020	COG1396	sequence-specific DNA binding
RvVAT039_04110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RvVAT039_04120	COG0697	spore germination
RvVAT039_04140	COG2968	Membrane
RvVAT039_04310	COG4387	Mu-like prophage protein GP36
RvVAT039_04330	COG4397	Mu-like prophage major head subunit gpT
RvVAT039_04370	COG4383	Mu-like prophage protein gp29
RvVAT039_04380	COG4373	Mu-like prophage FluMu protein gp28
RvVAT039_04650	COG1475	DNA binding
RvVAT039_04970	COG1278	Cold shock
RvVAT039_05030	COG0432	Pfam Uncharacterised protein family UPF0047
RvVAT039_05060	COG0583	DNA-binding transcription factor activity
RvVAT039_05070	COG3293	Transposase
RvVAT039_05120	COG1473	amidohydrolase
RvVAT039_05190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RvVAT039_05210	COG1268	BioY protein
RvVAT039_05220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RvVAT039_05240	COG0505	Belongs to the CarA family
RvVAT039_05250	COG0534	Mate efflux family protein
RvVAT039_05260	COG0583	DNA-binding transcription factor activity
RvVAT039_05270	COG0667	Aldo Keto reductase
RvVAT039_05280	COG2321	neutral zinc metallopeptidase
RvVAT039_05310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RvVAT039_05330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RvVAT039_05390	COG4641	Protein conserved in bacteria
RvVAT039_05390	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_05400	COG1522	sequence-specific DNA binding
RvVAT039_05410	COG0492	ferredoxin-NADP+ reductase activity
RvVAT039_05420	COG0583	DNA-binding transcription factor activity
RvVAT039_05430	COG0640	Transcriptional regulator
RvVAT039_05440	COG1902	pentaerythritol trinitrate reductase activity
RvVAT039_05480	COG0387	Pfam Sodium calcium exchanger
RvVAT039_05500	COG0436	Aminotransferase
RvVAT039_05530	COG1278	Cold shock
RvVAT039_05540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_05560	COG1846	Transcriptional regulator
RvVAT039_05570	COG0745	RESPONSE REGULATOR receiver
RvVAT039_05580	COG2205	protein histidine kinase activity
RvVAT039_05590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RvVAT039_05630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RvVAT039_05660	COG0006	proline dipeptidase activity
RvVAT039_05710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RvVAT039_05740	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_05760	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RvVAT039_05790	COG0193	aminoacyl-tRNA hydrolase activity
RvVAT039_05810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RvVAT039_05820	COG0012	GTP binding
RvVAT039_05860	COG0386	Belongs to the glutathione peroxidase family
RvVAT039_05890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RvVAT039_05900	COG2857	Cytochrome c1
RvVAT039_05900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RvVAT039_05950	COG1132	(ABC) transporter
RvVAT039_05960	COG1132	(ABC) transporter
RvVAT039_05970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RvVAT039_05990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_06010	COG0408	coproporphyrinogen oxidase activity
RvVAT039_06040	COG0617	tRNA 3'-terminal CCA addition
RvVAT039_06070	COG0714	Associated with various cellular activities
RvVAT039_06110	COG0454	-acetyltransferase
RvVAT039_06150	COG0435	Glutathione S-transferase
RvVAT039_06180	COG0740	serine-type endopeptidase activity
RvVAT039_06190	COG3135	benzoate transporter
RvVAT039_06200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RvVAT039_06260	COG3501	Rhs element vgr protein
RvVAT039_06320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RvVAT039_06320	COG0512	Glutamine amidotransferase of anthranilate synthase
RvVAT039_06340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RvVAT039_06350	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RvVAT039_06390	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RvVAT039_06420	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RvVAT039_06440	COG2197	response regulator
RvVAT039_06470	COG1435	thymidine kinase activity
RvVAT039_06500	COG4175	Glycine betaine
RvVAT039_06610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RvVAT039_06630	COG4115	mRNA cleavage
RvVAT039_06640	COG0366	Alpha amylase catalytic
RvVAT039_06660	COG1160	GTP binding
RvVAT039_06700	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
RvVAT039_06730	COG0024	Methionine aminopeptidase
RvVAT039_06740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_06750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RvVAT039_06760	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_06780	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_06800	COG0457	Tetratricopeptide repeat
RvVAT039_06820	COG0583	DNA-binding transcription factor activity
RvVAT039_06840	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_06850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_06870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_06880	COG0137	argininosuccinate synthase activity
RvVAT039_06950	COG2351	hydroxyisourate hydrolase activity
RvVAT039_06960	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
RvVAT039_06970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_06980	COG0174	glutamine synthetase
RvVAT039_07000	COG3195	allantoin biosynthetic process
RvVAT039_07000	COG3648	Uricase
RvVAT039_07010	COG1064	alcohol dehydrogenase
RvVAT039_07040	COG3706	GGDEF domain
RvVAT039_07070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_07080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RvVAT039_07080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_07090	COG2205	protein histidine kinase activity
RvVAT039_07090	COG0784	Response regulator, receiver
RvVAT039_07090	COG5002	protein histidine kinase activity
RvVAT039_07120	COG0513	Belongs to the DEAD box helicase family
RvVAT039_07150	COG1733	regulation of RNA biosynthetic process
RvVAT039_07180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RvVAT039_07210	COG1982	Orn Lys Arg decarboxylase major
RvVAT039_07340	COG3501	Rhs element vgr protein
RvVAT039_07530	COG3293	Transposase
RvVAT039_07570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RvVAT039_07630	COG0583	DNA-binding transcription factor activity
RvVAT039_07660	COG2308	Evidence 4 Homologs of previously reported genes of
RvVAT039_07680	COG2346	COG2346, Truncated hemoglobins
RvVAT039_07720	COG0493	'glutamate synthase
RvVAT039_07760	COG1309	transcriptional regulator
RvVAT039_07810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_07820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_07830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_07880	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RvVAT039_07890	COG0830	nickel cation binding
RvVAT039_07900	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
RvVAT039_07910	COG5002	protein histidine kinase activity
RvVAT039_07910	COG5001	Diguanylate cyclase
RvVAT039_07950	COG0804	urea catabolic process
RvVAT039_07960	COG1442	glycosyl transferase family 8
RvVAT039_07970	COG3755	Protein conserved in bacteria
RvVAT039_07980	COG0832	Belongs to the urease beta subunit family
RvVAT039_07990	COG3813	Protein conserved in bacteria
RvVAT039_08000	COG0831	urea catabolic process
RvVAT039_08010	COG0829	nickel cation binding
RvVAT039_08100	COG4251	negative regulation of phosphorylation
RvVAT039_08120	COG2205	protein histidine kinase activity
RvVAT039_08120	COG0784	Response regulator, receiver
RvVAT039_08170	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RvVAT039_08180	COG2894	cell division
RvVAT039_08190	COG0850	regulation of cytokinetic process
RvVAT039_08270	COG2814	Major facilitator Superfamily
RvVAT039_08290	COG1218	3'(2'),5'-bisphosphate nucleotidase
RvVAT039_08410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RvVAT039_08430	COG0564	pseudouridine synthase activity
RvVAT039_08440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_08440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RvVAT039_08450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RvVAT039_08470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RvVAT039_08500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RvVAT039_08520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RvVAT039_08560	COG1116	anion transmembrane transporter activity
RvVAT039_08580	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_08600	COG2249	NAD(P)H dehydrogenase (quinone) activity
RvVAT039_08650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RvVAT039_08720	COG1175	transmembrane transport
RvVAT039_08780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_08800	COG0482	sulfurtransferase activity
RvVAT039_08810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RvVAT039_08820	COG1122	ATPase activity
RvVAT039_09080	COG5005	Phage virion morphogenesis
RvVAT039_09200	COG4396	Host-nuclease inhibitor protein Gam
RvVAT039_09280	COG4774	siderophore transport
RvVAT039_09320	COG1120	ATPase activity
RvVAT039_09340	COG4774	siderophore transport
RvVAT039_09390	COG1294	oxidase, subunit
RvVAT039_09400	COG1271	oxidase subunit
RvVAT039_09410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RvVAT039_09460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_09470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RvVAT039_09480	COG0632	four-way junction helicase activity
RvVAT039_09490	COG2002	toxin-antitoxin pair type II binding
RvVAT039_09510	COG2255	four-way junction helicase activity
RvVAT039_09520	COG1408	metallophosphoesterase
RvVAT039_09530	COG0494	nUDIX hydrolase
RvVAT039_09560	COG0824	Thioesterase
RvVAT039_09600	COG0823	Involved in the tonB-independent uptake of proteins
RvVAT039_09610	COG2885	chlorophyll binding
RvVAT039_09630	COG0037	tRNA processing
RvVAT039_09640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RvVAT039_09650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RvVAT039_09660	COG0217	transcriptional regulatory protein
RvVAT039_09780	COG0840	transmembrane signaling receptor activity
RvVAT039_09790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RvVAT039_09800	COG1692	metallophosphoesterase
RvVAT039_09810	COG0126	phosphoglycerate kinase activity
RvVAT039_09820	COG3588	fructose-bisphosphate aldolase
RvVAT039_09830	COG0384	phenazine biosynthesis protein PhzF
RvVAT039_09900	COG0254	rRNA binding
RvVAT039_09910	COG1132	(ABC) transporter
RvVAT039_09950	COG0483	inositol monophosphate 1-phosphatase activity
RvVAT039_09970	COG0352	thiamine-phosphate diphosphorylase activity
RvVAT039_09990	COG0640	Transcriptional regulator
RvVAT039_10020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RvVAT039_10030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RvVAT039_10040	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RvVAT039_10050	COG0457	Tetratricopeptide repeat
RvVAT039_10060	COG0596	Alpha beta hydrolase
RvVAT039_10070	COG0469	pyruvate kinase activity
RvVAT039_10110	COG3750	Belongs to the UPF0335 family
RvVAT039_10150	COG0512	Glutamine amidotransferase of anthranilate synthase
RvVAT039_10150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RvVAT039_10160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_10180	COG5310	Homospermidine synthase
RvVAT039_10200	COG0737	Belongs to the 5'-nucleotidase family
RvVAT039_10210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RvVAT039_10230	COG0840	transmembrane signaling receptor activity
RvVAT039_10250	COG0602	queuosine metabolic process
RvVAT039_10260	COG0720	synthase
RvVAT039_10270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RvVAT039_10280	COG0330	HflC and HflK could
RvVAT039_10300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RvVAT039_10300	COG0517	IMP dehydrogenase activity
RvVAT039_10320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RvVAT039_10340	COG2951	lytic endotransglycosylase activity
RvVAT039_10360	COG0840	transmembrane signaling receptor activity
RvVAT039_10380	COG0070	glutamate synthase
RvVAT039_10380	COG0069	glutamate synthase activity
RvVAT039_10380	COG0067	glutamate synthase
RvVAT039_10400	COG0071	Belongs to the small heat shock protein (HSP20) family
RvVAT039_10500	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
RvVAT039_10500	COG0662	Cupin 2, conserved barrel domain protein
RvVAT039_10520	COG2308	Evidence 4 Homologs of previously reported genes of
RvVAT039_10520	COG2307	Protein conserved in bacteria
RvVAT039_10560	COG0058	SHG alpha-glucan phosphorylase activity
RvVAT039_10570	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RvVAT039_10580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RvVAT039_10590	COG0297	glycogen (starch) synthase activity
RvVAT039_10600	COG0033	Phosphoglucomutase
RvVAT039_10680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RvVAT039_10690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_10710	COG0446	pyridine nucleotide-disulphide oxidoreductase
RvVAT039_10710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_10740	COG1733	regulation of RNA biosynthetic process
RvVAT039_10750	COG3041	Addiction module toxin RelE StbE family
RvVAT039_10760	COG3077	Addiction module antitoxin, RelB DinJ family
RvVAT039_10830	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
RvVAT039_10840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RvVAT039_10850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_10860	COG1609	Transcriptional regulator
RvVAT039_10870	COG1846	Transcriptional regulator
RvVAT039_10890	COG0523	cobalamin synthesis protein
RvVAT039_10910	COG2972	Histidine kinase
RvVAT039_10910	COG0840	transmembrane signaling receptor activity
RvVAT039_10920	COG3047	cAMP biosynthetic process
RvVAT039_10970	COG0583	DNA-binding transcription factor activity
RvVAT039_11030	COG0800	Aldolase
RvVAT039_11040	COG2954	triphosphatase activity
RvVAT039_11060	COG2378	regulation of single-species biofilm formation
RvVAT039_11090	COG2199	diguanylate cyclase activity
RvVAT039_11090	COG2202	Pas domain
RvVAT039_11090	COG2200	EAL domain
RvVAT039_11130	COG0673	inositol 2-dehydrogenase activity
RvVAT039_11150	COG2115	Belongs to the xylose isomerase family
RvVAT039_11160	COG1070	Carbohydrate kinase
RvVAT039_11170	COG1609	Transcriptional regulator
RvVAT039_11200	COG1309	transcriptional regulator
RvVAT039_11210	COG1253	flavin adenine dinucleotide binding
RvVAT039_11250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RvVAT039_11280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RvVAT039_11320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RvVAT039_11330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RvVAT039_11340	COG0471	metal ion transport
RvVAT039_11340	COG3273	potassium ion transport
RvVAT039_11370	COG2274	protein secretion by the type I secretion system
RvVAT039_11440	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_11450	COG1473	amidohydrolase
RvVAT039_11480	COG0601	transmembrane transport
RvVAT039_11490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_11500	COG0842	Transport permease protein
RvVAT039_11510	COG0842	Transport permease protein
RvVAT039_11510	COG1129	ABC transporter
RvVAT039_11520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_11530	COG3191	aminopeptidase activity
RvVAT039_11540	COG3454	Phosphonate metabolism
RvVAT039_11560	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_11580	COG0601	transmembrane transport
RvVAT039_11590	COG0747	negative chemotaxis
RvVAT039_11610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_11620	COG1802	Transcriptional regulator
RvVAT039_11630	COG1904	glucuronate isomerase
RvVAT039_11640	COG1917	Cupin 2, conserved barrel domain protein
RvVAT039_11660	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_11670	COG0246	Mannitol dehydrogenase
RvVAT039_11680	COG1312	Catalyzes the dehydration of D-mannonate
RvVAT039_11690	COG2721	sulfolactate sulfo-lyase activity
RvVAT039_11710	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RvVAT039_11740	COG4213	ABC transporter substrate-binding protein
RvVAT039_11760	COG4214	carbohydrate transport
RvVAT039_11780	COG0129	dihydroxy-acid dehydratase activity
RvVAT039_11810	COG3734	2-keto-3-deoxy-galactonokinase
RvVAT039_11820	COG0800	Aldolase
RvVAT039_11830	COG2832	Protein of unknown function (DUF454)
RvVAT039_11840	COG0697	spore germination
RvVAT039_11850	COG2186	Transcriptional regulator
RvVAT039_11860	COG2807	transmembrane transport
RvVAT039_11870	COG2373	Large extracellular alpha-helical protein
RvVAT039_11880	COG4953	penicillin-binding protein 1C
RvVAT039_11890	COG0840	transmembrane signaling receptor activity
RvVAT039_11890	COG2972	Histidine kinase
RvVAT039_11900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_11910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RvVAT039_11920	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_11940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_11960	COG0747	negative chemotaxis
RvVAT039_12000	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_12070	COG0419	ATPase involved in DNA repair
RvVAT039_12080	COG0840	transmembrane signaling receptor activity
RvVAT039_12100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RvVAT039_12120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_12130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_12150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RvVAT039_12180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_12200	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RvVAT039_12260	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_12290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RvVAT039_12310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_12340	COG1793	dna ligase
RvVAT039_12380	COG0783	Belongs to the Dps family
RvVAT039_12400	COG0784	Response regulator, receiver
RvVAT039_12480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_12510	COG0848	biopolymer transport protein
RvVAT039_12530	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RvVAT039_12560	COG0010	Belongs to the arginase family
RvVAT039_12600	COG1940	carbohydrate kinase activity
RvVAT039_12640	COG0572	uridine kinase
RvVAT039_12650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_12660	COG0765	amino acid transport
RvVAT039_12670	COG0765	amino acid transport
RvVAT039_12680	COG4598	ABC transporter
RvVAT039_12720	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_12730	COG1228	amidohydrolase
RvVAT039_12740	COG2986	histidine ammonia-lyase
RvVAT039_12760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RvVAT039_12800	COG1289	transmembrane transporter activity
RvVAT039_12850	COG0346	lactoylglutathione lyase activity
RvVAT039_12860	COG0400	carboxylic ester hydrolase activity
RvVAT039_12900	COG3307	-O-antigen
RvVAT039_12910	COG1596	polysaccharide export
RvVAT039_12920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RvVAT039_12950	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_12960	COG2327	Polysaccharide pyruvyl transferase
RvVAT039_12970	COG0463	Glycosyl transferase, family 2
RvVAT039_12980	COG2244	polysaccharide biosynthetic process
RvVAT039_12990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RvVAT039_13000	COG2273	Hydrolase Family 16
RvVAT039_13010	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_13020	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_13030	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_13040	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_13050	COG3206	protein involved in exopolysaccharide biosynthesis
RvVAT039_13050	COG0489	protein tyrosine kinase activity
RvVAT039_13060	COG0469	pyruvate kinase activity
RvVAT039_13080	COG0542	response to heat
RvVAT039_13100	COG2890	protein-(glutamine-N5) methyltransferase activity
RvVAT039_13110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RvVAT039_13130	COG0527	aspartate kinase activity
RvVAT039_13180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RvVAT039_13200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RvVAT039_13210	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RvVAT039_13230	COG2226	methyltransferase
RvVAT039_13260	COG0494	nUDIX hydrolase
RvVAT039_13280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RvVAT039_13290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RvVAT039_13310	COG0653	protein targeting
RvVAT039_13340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RvVAT039_13360	COG2801	Transposase and inactivated derivatives
RvVAT039_13410	COG3293	Transposase
RvVAT039_13450	COG0667	Aldo Keto reductase
RvVAT039_13530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RvVAT039_13550	COG0300	oxidoreductase activity
RvVAT039_13580	COG2086	electron transfer activity
RvVAT039_13600	COG0840	transmembrane signaling receptor activity
RvVAT039_13600	COG2972	Histidine kinase
RvVAT039_13610	COG1250	3-hydroxyacyl-CoA dehydrogenase
RvVAT039_13620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RvVAT039_13630	COG0165	Argininosuccinate lyase
RvVAT039_13650	COG0019	diaminopimelate decarboxylase activity
RvVAT039_13700	COG2884	Cell division ATP-binding protein ftsE
RvVAT039_13740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RvVAT039_13760	COG0287	Prephenate dehydrogenase
RvVAT039_13770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_13780	COG2226	methyltransferase
RvVAT039_13790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_13840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RvVAT039_13850	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RvVAT039_13910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RvVAT039_13920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RvVAT039_13940	COG4974	Belongs to the 'phage' integrase family
RvVAT039_13950	COG0825	malonyl-CoA metabolic process
RvVAT039_13960	COG3034	peptidoglycan biosynthetic process
RvVAT039_13980	COG0523	cobalamin synthesis protein
RvVAT039_13990	COG1686	Belongs to the peptidase S11 family
RvVAT039_14000	COG1473	amidohydrolase
RvVAT039_14010	COG0628	permease
RvVAT039_14030	COG2771	luxR family
RvVAT039_14040	COG1766	The M ring may be actively involved in energy transduction
RvVAT039_14060	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RvVAT039_14070	COG0745	RESPONSE REGULATOR receiver
RvVAT039_14080	COG2201	protein-glutamate methylesterase activity
RvVAT039_14090	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RvVAT039_14100	COG0835	chemotaxis
RvVAT039_14110	COG0643	Histidine kinase
RvVAT039_14110	COG2198	Histidine kinase
RvVAT039_14120	COG0745	RESPONSE REGULATOR receiver
RvVAT039_14140	COG0840	transmembrane signaling receptor activity
RvVAT039_14160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RvVAT039_14180	COG0156	8-amino-7-oxononanoate synthase activity
RvVAT039_14200	COG0729	surface antigen
RvVAT039_14230	COG0835	chemotaxis
RvVAT039_14240	COG2223	nitrite transmembrane transporter activity
RvVAT039_14260	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RvVAT039_14270	COG3383	formate dehydrogenase (NAD+) activity
RvVAT039_14300	COG0583	DNA-binding transcription factor activity
RvVAT039_14310	COG0640	Transcriptional regulator
RvVAT039_14320	COG0039	L-malate dehydrogenase activity
RvVAT039_14330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RvVAT039_14340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RvVAT039_14350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RvVAT039_14360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RvVAT039_14370	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RvVAT039_14400	COG0840	transmembrane signaling receptor activity
RvVAT039_14410	COG4974	Belongs to the 'phage' integrase family
RvVAT039_14470	COG0508	dehydrogenase complex catalyzes the overall conversion of
RvVAT039_14490	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RvVAT039_14510	COG0045	succinate-CoA ligase (ADP-forming) activity
RvVAT039_14520	COG0039	L-malate dehydrogenase activity
RvVAT039_14530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RvVAT039_14620	COG2350	Protein conserved in bacteria
RvVAT039_14630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RvVAT039_14640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RvVAT039_14650	COG0181	hydroxymethylbilane synthase activity
RvVAT039_14740	COG1872	DUF167
RvVAT039_14750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RvVAT039_14790	COG0339	signal peptide processing
RvVAT039_14810	COG0137	argininosuccinate synthase activity
RvVAT039_14820	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_14850	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_14870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RvVAT039_14900	COG2154	pterin-4-alpha-carbinolamine dehydratase
RvVAT039_14910	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RvVAT039_14930	COG1136	(ABC) transporter
RvVAT039_14940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RvVAT039_14950	COG0670	Belongs to the BI1 family
RvVAT039_14990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RvVAT039_15000	COG4133	protoheme IX ABC transporter activity
RvVAT039_15010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RvVAT039_15020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RvVAT039_15060	COG2917	probably involved in intracellular septation
RvVAT039_15070	COG0552	protein localization to endoplasmic reticulum
RvVAT039_15080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RvVAT039_15090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RvVAT039_15120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RvVAT039_15130	COG1605	Chorismate mutase
RvVAT039_15130	COG0287	Prephenate dehydrogenase
RvVAT039_15140	COG0228	four-way junction DNA binding
RvVAT039_15150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RvVAT039_15160	COG0336	Belongs to the RNA methyltransferase TrmD family
RvVAT039_15180	COG0335	large ribosomal subunit rRNA binding
RvVAT039_15210	COG2372	response to copper ion
RvVAT039_15220	COG1276	copper resistance
RvVAT039_15220	COG2372	response to copper ion
RvVAT039_15240	COG0765	amino acid transport
RvVAT039_15270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RvVAT039_15300	COG0745	RESPONSE REGULATOR receiver
RvVAT039_15340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RvVAT039_15350	COG1674	ftsk spoiiie
RvVAT039_15360	COG0004	ammonium transporteR
RvVAT039_15370	COG0347	Belongs to the P(II) protein family
RvVAT039_15380	COG1946	Acyl-CoA thioesterase
RvVAT039_15390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_15400	COG2835	tetraacyldisaccharide 4'-kinase activity
RvVAT039_15410	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RvVAT039_15420	COG3118	belongs to the thioredoxin family
RvVAT039_15450	COG2017	converts alpha-aldose to the beta-anomer
RvVAT039_15480	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RvVAT039_15510	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RvVAT039_15590	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
RvVAT039_15650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RvVAT039_15660	COG0799	negative regulation of ribosome biogenesis
RvVAT039_15670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RvVAT039_15680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RvVAT039_15690	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RvVAT039_15700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RvVAT039_15740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RvVAT039_15750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RvVAT039_15780	COG0138	bifunctional purine biosynthesis protein purh
RvVAT039_15800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RvVAT039_15800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RvVAT039_15810	COG0501	Belongs to the peptidase M48B family
RvVAT039_15840	COG0793	Belongs to the peptidase S41A family
RvVAT039_15860	COG0494	nUDIX hydrolase
RvVAT039_15870	COG1192	Involved in chromosome partitioning
RvVAT039_15920	COG2201	protein-glutamate methylesterase activity
RvVAT039_15940	COG0835	chemotaxis
RvVAT039_15950	COG0840	transmembrane signaling receptor activity
RvVAT039_15960	COG3290	protein histidine kinase activity
RvVAT039_15960	COG0840	transmembrane signaling receptor activity
RvVAT039_15970	COG0840	transmembrane signaling receptor activity
RvVAT039_15980	COG0835	chemotaxis
RvVAT039_15990	COG2198	Histidine kinase
RvVAT039_15990	COG0643	Histidine kinase
RvVAT039_16000	COG0745	RESPONSE REGULATOR receiver
RvVAT039_16050	COG1522	sequence-specific DNA binding
RvVAT039_16080	COG4221	oxidoreductase activity
RvVAT039_16110	COG0738	Major facilitator superfamily
RvVAT039_16120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RvVAT039_16130	COG2885	chlorophyll binding
RvVAT039_16150	COG0142	geranyltranstransferase activity
RvVAT039_16160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RvVAT039_16180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RvVAT039_16190	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
RvVAT039_16200	COG0183	Belongs to the thiolase family
RvVAT039_16260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RvVAT039_16300	COG2301	Belongs to the HpcH HpaI aldolase family
RvVAT039_16320	COG0066	3-isopropylmalate dehydratase activity
RvVAT039_16330	COG0473	3-isopropylmalate dehydrogenase activity
RvVAT039_16340	COG0671	phosphoesterase, PA-phosphatase related
RvVAT039_16370	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RvVAT039_16390	COG2010	Cytochrome c
RvVAT039_16400	COG0288	reversible hydration of carbon dioxide
RvVAT039_16410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RvVAT039_16420	COG2902	Dehydrogenase
RvVAT039_16440	COG3459	Glycosyltransferase 36 associated
RvVAT039_16450	COG1473	amidohydrolase
RvVAT039_16480	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RvVAT039_16500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RvVAT039_16520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RvVAT039_16530	COG0495	leucyl-tRNA aminoacylation
RvVAT039_16590	COG0357	Ribosomal RNA small subunit methyltransferase G
RvVAT039_16600	COG0445	tRNA wobble uridine modification
RvVAT039_16620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RvVAT039_16630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RvVAT039_16650	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RvVAT039_16660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RvVAT039_16670	COG0424	maF-like protein
RvVAT039_16680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RvVAT039_16690	COG0237	dephospho-CoA kinase activity
RvVAT039_16720	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RvVAT039_16750	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RvVAT039_16830	COG0135	phosphoribosylanthranilate isomerase activity
RvVAT039_16840	COG0133	tryptophan synthase activity
RvVAT039_16850	COG0159	tryptophan synthase activity
RvVAT039_16860	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RvVAT039_16870	COG0285	dihydrofolate synthase activity
RvVAT039_16920	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RvVAT039_16930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RvVAT039_16940	COG0131	Imidazoleglycerol-phosphate dehydratase
RvVAT039_16950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RvVAT039_16960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RvVAT039_16970	COG0107	imidazoleglycerol-phosphate synthase activity
RvVAT039_16980	COG0140	phosphoribosyl-ATP diphosphatase activity
RvVAT039_16990	COG1072	(Pantothenic acid kinase))
RvVAT039_17020	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RvVAT039_17030	COG0745	RESPONSE REGULATOR receiver
RvVAT039_17040	COG0642	Histidine kinase
RvVAT039_17050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RvVAT039_17050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RvVAT039_17060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RvVAT039_17070	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RvVAT039_17080	COG2205	protein histidine kinase activity
RvVAT039_17090	COG3178	'Phosphotransferase
RvVAT039_17100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RvVAT039_17110	COG2887	Belongs to the helicase family. UvrD subfamily
RvVAT039_17120	COG1074	ATP-dependent DNA helicase activity
RvVAT039_17130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RvVAT039_17160	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
RvVAT039_17180	COG1643	Atp-dependent helicase
RvVAT039_17190	COG2423	ornithine cyclodeaminase activity
RvVAT039_17200	COG2814	Major facilitator Superfamily
RvVAT039_17210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_17220	COG1609	Transcriptional regulator
RvVAT039_17240	COG0673	inositol 2-dehydrogenase activity
RvVAT039_17260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_17270	COG3962	Belongs to the TPP enzyme family
RvVAT039_17300	COG3718	enzyme involved in inositol metabolism
RvVAT039_17340	COG4221	oxidoreductase activity
RvVAT039_17350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_17380	COG1595	DNA-templated transcription, initiation
RvVAT039_17390	COG3806	Anti-sigma factor
RvVAT039_17430	COG3842	ATPase activity
RvVAT039_17440	COG3842	ATPase activity
RvVAT039_17460	COG0395	ABC-type sugar transport system, permease component
RvVAT039_17490	COG3474	cytochrome
RvVAT039_17500	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RvVAT039_17510	COG0077	Prephenate dehydratase
RvVAT039_17510	COG1605	Chorismate mutase
RvVAT039_17530	COG2816	NAD+ diphosphatase activity
RvVAT039_17550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RvVAT039_17560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RvVAT039_17580	COG3422	double-strand break repair
RvVAT039_17610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RvVAT039_17620	COG0481	GTPase activity
RvVAT039_17650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RvVAT039_17660	COG1607	acyl-coa hydrolase
RvVAT039_17710	COG1393	Belongs to the ArsC family
RvVAT039_17720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RvVAT039_17740	COG2309	aminopeptidase activity
RvVAT039_17770	COG1278	Cold shock
RvVAT039_17780	COG1570	exodeoxyribonuclease VII activity
RvVAT039_17870	COG0667	Aldo Keto reductase
RvVAT039_17900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RvVAT039_17910	COG2951	lytic endotransglycosylase activity
RvVAT039_17960	COG2814	Major facilitator Superfamily
RvVAT039_17970	COG0779	Required for maturation of 30S ribosomal subunits
RvVAT039_17980	COG0195	Participates in both transcription termination and antitermination
RvVAT039_17980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RvVAT039_18000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RvVAT039_18010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RvVAT039_18020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RvVAT039_18030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RvVAT039_18050	COG1185	polyribonucleotide nucleotidyltransferase activity
RvVAT039_18060	COG2813	Specifically methylates the guanine in position
RvVAT039_18070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RvVAT039_18090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RvVAT039_18110	COG2860	membrane
RvVAT039_18130	COG0477	Major facilitator Superfamily
RvVAT039_18150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RvVAT039_18160	COG0539	negative regulation of cytoplasmic translation
RvVAT039_18200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RvVAT039_18220	COG0745	RESPONSE REGULATOR receiver
RvVAT039_18230	COG2205	protein histidine kinase activity
RvVAT039_18240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RvVAT039_18250	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RvVAT039_18260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RvVAT039_18280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RvVAT039_18280	COG0072	phenylalanine-tRNA ligase activity
RvVAT039_18360	COG4964	Belongs to the GSP D family
RvVAT039_18440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RvVAT039_18450	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RvVAT039_18460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RvVAT039_18480	COG0588	phosphoglycerate mutase activity
RvVAT039_18490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RvVAT039_18500	COG1132	(ABC) transporter
RvVAT039_18510	COG0837	glucose binding
RvVAT039_18520	COG1803	Methylglyoxal synthase
RvVAT039_18530	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
RvVAT039_18540	COG4166	transmembrane transport
RvVAT039_18550	COG4174	ABC transporter (Permease)
RvVAT039_18560	COG4239	(ABC) transporter, permease
RvVAT039_18570	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_18580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RvVAT039_18600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RvVAT039_18700	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RvVAT039_18710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RvVAT039_18720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RvVAT039_18730	COG2188	Transcriptional regulator
RvVAT039_18740	COG3624	Phosphonate C-P lyase system protein PhnG
RvVAT039_18750	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
RvVAT039_18760	COG3626	phosphonate metabolism
RvVAT039_18770	COG3627	carbon phosphorus lyase activity
RvVAT039_18780	COG4107	phosphonate C-P lyase system protein PhnK
RvVAT039_18790	COG4778	phosphonate C-P lyase system protein PhnL
RvVAT039_18810	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RvVAT039_18820	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
RvVAT039_18840	COG3639	organic phosphonate transmembrane transporter activity
RvVAT039_18850	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RvVAT039_18860	COG3454	Phosphonate metabolism
RvVAT039_18870	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
RvVAT039_18900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RvVAT039_18910	COG2353	YceI-like domain
RvVAT039_18920	COG2353	YceI-like domain
RvVAT039_18940	COG0791	NLP P60 protein
RvVAT039_18950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RvVAT039_18950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RvVAT039_18970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_18990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RvVAT039_19020	COG0443	Heat shock 70 kDa protein
RvVAT039_19040	COG0484	heat shock protein binding
RvVAT039_19050	COG2900	Belongs to the SlyX family
RvVAT039_19060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RvVAT039_19090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_19110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_19120	COG5001	Diguanylate cyclase
RvVAT039_19130	COG3002	Belongs to the UPF0753 family
RvVAT039_19140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RvVAT039_19190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RvVAT039_19190	COG0519	Catalyzes the synthesis of GMP from XMP
RvVAT039_19220	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
RvVAT039_19270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RvVAT039_19270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RvVAT039_19280	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RvVAT039_19300	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RvVAT039_19320	COG1968	undecaprenyl-diphosphatase activity
RvVAT039_19360	COG0284	orotidine-5'-phosphate decarboxylase activity
RvVAT039_19380	COG3963	phosphatidate phosphatase activity
RvVAT039_19400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RvVAT039_19410	COG0792	nuclease activity
RvVAT039_19420	COG1653	transport
RvVAT039_19430	COG1175	transmembrane transport
RvVAT039_19440	COG0395	ABC-type sugar transport system, permease component
RvVAT039_19450	COG3842	ATPase activity
RvVAT039_19470	COG0189	ligase activity
RvVAT039_19480	COG0606	chelatase, subunit chli
RvVAT039_19510	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_19520	COG0756	dUTP diphosphatase activity
RvVAT039_19530	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
RvVAT039_19540	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RvVAT039_19550	COG1877	trehalose-phosphatase activity
RvVAT039_19590	COG1741	Belongs to the pirin family
RvVAT039_19610	COG0583	DNA-binding transcription factor activity
RvVAT039_19640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RvVAT039_19650	COG3920	Histidine kinase
RvVAT039_19660	COG0784	Response regulator, receiver
RvVAT039_19670	COG2198	Histidine kinase
RvVAT039_19670	COG0784	Response regulator, receiver
RvVAT039_19670	COG2205	protein histidine kinase activity
RvVAT039_19670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_19680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RvVAT039_19690	COG2226	methyltransferase
RvVAT039_19700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RvVAT039_19710	COG0268	Binds directly to 16S ribosomal RNA
RvVAT039_19720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RvVAT039_19740	COG0697	spore germination
RvVAT039_19750	COG2226	methyltransferase
RvVAT039_19760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RvVAT039_19770	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RvVAT039_19790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RvVAT039_19800	COG1420	regulation of RNA biosynthetic process
RvVAT039_19810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RvVAT039_19820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RvVAT039_19830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RvVAT039_19850	COG1137	ATPase activity
RvVAT039_19860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RvVAT039_19880	COG0776	regulation of translation
RvVAT039_19910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RvVAT039_19920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RvVAT039_19960	COG0583	DNA-binding transcription factor activity
RvVAT039_19970	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RvVAT039_19980	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RvVAT039_20000	COG0346	lactoylglutathione lyase activity
RvVAT039_20020	COG0180	Tryptophanyl-tRNA synthetase
RvVAT039_20040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RvVAT039_20050	COG1214	PFAM Peptidase M22, glycoprotease
RvVAT039_20090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RvVAT039_20100	COG1702	phosphate starvation-inducible protein PhoH
RvVAT039_20110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RvVAT039_20120	COG4535	Mg2 and Co2 transporter CorC
RvVAT039_20130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RvVAT039_20140	COG1396	sequence-specific DNA binding
RvVAT039_20150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RvVAT039_20160	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RvVAT039_20180	COG0071	Belongs to the small heat shock protein (HSP20) family
RvVAT039_20220	COG0840	transmembrane signaling receptor activity
RvVAT039_20240	COG2205	protein histidine kinase activity
RvVAT039_20250	COG0594	ribonuclease P activity
RvVAT039_20260	COG0706	membrane insertase activity
RvVAT039_20270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RvVAT039_20280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
RvVAT039_20310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RvVAT039_20320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_20340	COG1749	Flagellar hook protein flgE
RvVAT039_20360	COG2171	N-acyltransferase activity
RvVAT039_20370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_20430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RvVAT039_20440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RvVAT039_20460	COG0745	RESPONSE REGULATOR receiver
RvVAT039_20470	COG0704	Plays a role in the regulation of phosphate uptake
RvVAT039_20480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RvVAT039_20500	COG0573	inorganic phosphate transmembrane transporter activity
RvVAT039_20520	COG5002	protein histidine kinase activity
RvVAT039_20530	COG2326	polyphosphate kinase activity
RvVAT039_20600	COG2188	Transcriptional regulator
RvVAT039_20610	COG2986	histidine ammonia-lyase
RvVAT039_20650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RvVAT039_20660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
RvVAT039_20680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RvVAT039_20730	COG0427	acetyl-CoA hydrolase
RvVAT039_20750	COG3938	Belongs to the proline racemase family
RvVAT039_20760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_20770	COG0745	RESPONSE REGULATOR receiver
RvVAT039_20810	COG0418	dihydroorotase activity
RvVAT039_20820	COG3706	GGDEF domain
RvVAT039_20830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RvVAT039_20850	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_20860	COG0166	Belongs to the GPI family
RvVAT039_20870	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_20920	COG0101	tRNA pseudouridine synthase activity
RvVAT039_20930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RvVAT039_20940	COG0242	peptide deformylase activity
RvVAT039_20950	COG2967	ApaG domain
RvVAT039_20970	COG0717	Belongs to the dCTP deaminase family
RvVAT039_21020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_21070	COG0167	dihydroorotate dehydrogenase activity
RvVAT039_21110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RvVAT039_21150	COG1250	3-hydroxyacyl-CoA dehydrogenase
RvVAT039_21150	COG1024	Enoyl-CoA hydratase
RvVAT039_21160	COG0183	Belongs to the thiolase family
RvVAT039_21170	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_21210	COG1785	Belongs to the alkaline phosphatase family
RvVAT039_21230	COG1136	(ABC) transporter
RvVAT039_21260	COG5001	Diguanylate cyclase
RvVAT039_21260	COG2203	Gaf domain
RvVAT039_21260	COG4251	negative regulation of phosphorylation
RvVAT039_21260	COG3706	GGDEF domain
RvVAT039_21270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RvVAT039_21290	COG1201	RNA secondary structure unwinding
RvVAT039_21330	COG1047	Peptidyl-prolyl cis-trans
RvVAT039_21340	COG2205	protein histidine kinase activity
RvVAT039_21340	COG2198	Histidine kinase
RvVAT039_21340	COG0784	Response regulator, receiver
RvVAT039_21350	COG1970	mechanosensitive ion channel activity
RvVAT039_21360	COG0436	Aminotransferase
RvVAT039_21380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RvVAT039_21420	COG1216	Glycosyl transferase, family 2
RvVAT039_21460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RvVAT039_21470	COG0424	maF-like protein
RvVAT039_21480	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RvVAT039_21500	COG5328	Belongs to the UPF0262 family
RvVAT039_21510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RvVAT039_21530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RvVAT039_21580	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_21600	COG0488	(ABC) transporter
RvVAT039_21650	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RvVAT039_21660	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RvVAT039_21670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RvVAT039_21680	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RvVAT039_21690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RvVAT039_21700	COG4786	Flagellar basal body rod
RvVAT039_21710	COG1157	protein secretion by the type III secretion system
RvVAT039_21730	COG1815	bacterial-type flagellum-dependent cell motility
RvVAT039_21740	COG1558	bacterial-type flagellum-dependent cell motility
RvVAT039_21750	COG1677	Flagellar hook-basal body complex protein FliE
RvVAT039_21760	COG4786	Flagellar basal body rod
RvVAT039_21770	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
RvVAT039_21780	COG1706	bacterial-type flagellum-dependent cell motility
RvVAT039_21800	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RvVAT039_21820	COG1338	Plays a role in the flagellum-specific transport system
RvVAT039_21830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_21840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_21850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_21860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_21870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_21890	COG1360	Flagellar Motor Protein
RvVAT039_21940	COG1749	Flagellar hook protein flgE
RvVAT039_21980	COG5443	negative regulation of bacterial-type flagellum assembly
RvVAT039_21990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RvVAT039_22000	COG4794	Type iii secretion
RvVAT039_22010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RvVAT039_22090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RvVAT039_22100	COG1609	Transcriptional regulator
RvVAT039_22110	COG1653	transport
RvVAT039_22120	COG1175	transmembrane transport
RvVAT039_22130	COG0395	ABC-type sugar transport system, permease component
RvVAT039_22140	COG0366	Alpha amylase catalytic
RvVAT039_22150	COG3842	ATPase activity
RvVAT039_22180	COG3493	citrate carrier protein
RvVAT039_22200	COG3293	Transposase
RvVAT039_22230	COG0129	dihydroxy-acid dehydratase activity
RvVAT039_22240	COG0363	glucosamine-6-phosphate deaminase activity
RvVAT039_22250	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RvVAT039_22260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_22280	COG2081	HI0933 family
RvVAT039_22320	COG0840	transmembrane signaling receptor activity
RvVAT039_22320	COG2972	Histidine kinase
RvVAT039_22390	COG2224	Isocitrate lyase
RvVAT039_22420	COG3842	ATPase activity
RvVAT039_22430	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_22440	COG1177	transmembrane transport
RvVAT039_22460	COG2205	protein histidine kinase activity
RvVAT039_22570	COG1959	2 iron, 2 sulfur cluster binding
RvVAT039_22580	COG3265	gluconokinase activity
RvVAT039_22590	COG2134	cdp-diacylglycerol pyrophosphatase
RvVAT039_22600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_22610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RvVAT039_22650	COG0579	oxidoreductase
RvVAT039_22700	COG0248	Ppx GppA phosphatase
RvVAT039_22710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RvVAT039_22730	COG3300	MHYT domain
RvVAT039_22730	COG5001	Diguanylate cyclase
RvVAT039_22740	COG0784	Response regulator, receiver
RvVAT039_22740	COG2198	Histidine kinase
RvVAT039_22740	COG5002	protein histidine kinase activity
RvVAT039_22750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RvVAT039_22770	COG1663	tetraacyldisaccharide 4'-kinase activity
RvVAT039_22790	COG1519	Transferase
RvVAT039_22810	COG1218	3'(2'),5'-bisphosphate nucleotidase
RvVAT039_22820	COG0312	modulator of DNA gyrase
RvVAT039_22830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RvVAT039_22830	COG0475	glutathione-regulated potassium exporter activity
RvVAT039_22850	COG0742	ribosomal rna small subunit methyltransferase
RvVAT039_22860	COG1187	pseudouridine synthase activity
RvVAT039_22870	COG0590	tRNA wobble adenosine to inosine editing
RvVAT039_22890	COG0477	Major facilitator Superfamily
RvVAT039_22910	COG3386	PFAM SMP-30 Gluconolaconase
RvVAT039_22920	COG2771	luxR family
RvVAT039_22960	COG0598	Magnesium transport protein CorA
RvVAT039_22970	COG3158	transport of potassium into the cell
RvVAT039_22990	COG0356	it plays a direct role in the translocation of protons across the membrane
RvVAT039_23010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RvVAT039_23020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RvVAT039_23030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RvVAT039_23060	COG0521	Mo-molybdopterin cofactor biosynthetic process
RvVAT039_23070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RvVAT039_23090	COG0142	geranyltranstransferase activity
RvVAT039_23110	COG4106	trans-aconitate 2-methyltransferase activity
RvVAT039_23150	COG0752	glycyl-tRNA synthetase alpha subunit
RvVAT039_23170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RvVAT039_23180	COG0751	glycine-tRNA ligase activity
RvVAT039_23190	COG1683	Conserved Protein
RvVAT039_23200	COG0840	transmembrane signaling receptor activity
RvVAT039_23200	COG0840	transmembrane signaling receptor activity
RvVAT039_23230	COG0151	Belongs to the GarS family
RvVAT039_23250	COG2183	response to ionizing radiation
RvVAT039_23260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_23270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RvVAT039_23320	COG0725	ABC transporter, periplasmic molybdate-binding protein
RvVAT039_23330	COG4149	molybdate abc transporter
RvVAT039_23340	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RvVAT039_23370	COG0009	L-threonylcarbamoyladenylate synthase
RvVAT039_23410	COG1136	(ABC) transporter
RvVAT039_23450	COG2972	Histidine kinase
RvVAT039_23450	COG0840	transmembrane signaling receptor activity
RvVAT039_23470	COG4638	Rieske (2fe-2S)
RvVAT039_23520	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_23530	COG1024	Enoyl-CoA hydratase
RvVAT039_23560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RvVAT039_23570	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RvVAT039_23580	COG0840	transmembrane signaling receptor activity
RvVAT039_23590	COG0840	transmembrane signaling receptor activity
RvVAT039_23600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RvVAT039_23610	COG1722	exodeoxyribonuclease VII activity
RvVAT039_23620	COG0123	including yeast histone deacetylase and acetoin utilization protein
RvVAT039_23640	COG1268	BioY protein
RvVAT039_23650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RvVAT039_23660	COG1122	ATPase activity
RvVAT039_23680	COG3214	Protein conserved in bacteria
RvVAT039_23720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RvVAT039_23720	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RvVAT039_23730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RvVAT039_23740	COG3300	MHYT domain
RvVAT039_23740	COG5001	Diguanylate cyclase
RvVAT039_23770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RvVAT039_23780	COG0484	heat shock protein binding
RvVAT039_23800	COG0259	pyridoxamine-phosphate oxidase activity
RvVAT039_23820	COG2814	Major facilitator Superfamily
RvVAT039_23830	COG0789	Transcriptional regulator
RvVAT039_23840	COG1686	Belongs to the peptidase S11 family
RvVAT039_23870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_23890	COG0312	modulator of DNA gyrase
RvVAT039_23920	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RvVAT039_23930	COG0109	protoheme IX farnesyltransferase activity
RvVAT039_23950	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
RvVAT039_23980	COG3346	SURF1 family
RvVAT039_24000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RvVAT039_24020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RvVAT039_24030	COG0328	RNA-DNA hybrid ribonuclease activity
RvVAT039_24050	COG0803	Belongs to the bacterial solute-binding protein 9 family
RvVAT039_24080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RvVAT039_24080	COG0678	peroxiredoxin activity
RvVAT039_24100	COG1678	Uncharacterized ACR, COG1678
RvVAT039_24120	COG0640	Transcriptional regulator
RvVAT039_24130	COG5001	Diguanylate cyclase
RvVAT039_24140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RvVAT039_24150	COG0612	Peptidase, M16
RvVAT039_24180	COG1597	lipid kinase activity
RvVAT039_24190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RvVAT039_24220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
RvVAT039_24280	COG1194	a g-specific adenine glycosylase
RvVAT039_24310	COG1196	nuclear chromosome segregation
RvVAT039_24350	COG2814	Major facilitator Superfamily
RvVAT039_24380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RvVAT039_24380	COG0574	Belongs to the PEP-utilizing enzyme family
RvVAT039_24450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_24480	COG0840	transmembrane signaling receptor activity
RvVAT039_24490	COG0175	sulfate reduction
RvVAT039_24500	COG0175	sulfate reduction
RvVAT039_24510	COG2895	sulfate adenylyltransferase (ATP) activity
RvVAT039_24520	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_24530	COG1309	transcriptional regulator
RvVAT039_24540	COG1609	Transcriptional regulator
RvVAT039_24560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_24580	COG0693	protein deglycase activity
RvVAT039_24610	COG0038	chloride channel
RvVAT039_24620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RvVAT039_24670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RvVAT039_24680	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_24690	COG0625	glutathione transferase activity
RvVAT039_24700	COG3119	arylsulfatase activity
RvVAT039_24710	COG1309	transcriptional regulator
RvVAT039_24720	COG4943	cyclic-guanylate-specific phosphodiesterase activity
RvVAT039_24750	COG0840	transmembrane signaling receptor activity
RvVAT039_24760	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
RvVAT039_24800	COG1349	DNA-binding transcription factor activity
RvVAT039_24900	COG0477	Major facilitator Superfamily
RvVAT039_24920	COG0778	Nitroreductase
RvVAT039_24970	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_24970	COG1388	LysM domain
RvVAT039_24980	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_24990	COG1846	Transcriptional regulator
RvVAT039_25000	COG1764	response to oxidative stress
RvVAT039_25030	COG0784	Response regulator, receiver
RvVAT039_25030	COG4191	Histidine kinase
RvVAT039_25040	COG3265	gluconokinase activity
RvVAT039_25060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RvVAT039_25070	COG0840	transmembrane signaling receptor activity
RvVAT039_25080	COG0840	transmembrane signaling receptor activity
RvVAT039_25100	COG0433	COG0433 Predicted ATPase
RvVAT039_25140	COG0840	transmembrane signaling receptor activity
RvVAT039_25150	COG1968	undecaprenyl-diphosphatase activity
RvVAT039_25170	COG4214	carbohydrate transport
RvVAT039_25180	COG4213	ABC transporter substrate-binding protein
RvVAT039_25190	COG1940	carbohydrate kinase activity
RvVAT039_25190	COG1846	Transcriptional regulator
RvVAT039_25230	COG1120	ATPase activity
RvVAT039_25240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_25270	COG2226	methyltransferase
RvVAT039_25330	COG2010	Cytochrome c
RvVAT039_25360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RvVAT039_25380	COG1733	regulation of RNA biosynthetic process
RvVAT039_25400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RvVAT039_25430	COG5001	Diguanylate cyclase
RvVAT039_25430	COG3447	MASE1 domain protein
RvVAT039_25430	COG5002	protein histidine kinase activity
RvVAT039_25440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_25520	COG2514	catechol 2,3-dioxygenase activity
RvVAT039_25550	COG3788	relative of glutathione S-transferase, MAPEG superfamily
RvVAT039_25560	COG1272	protein, Hemolysin III
RvVAT039_25570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_25610	COG4957	zinc ion binding
RvVAT039_25620	COG1320	monovalent cation:proton antiporter activity
RvVAT039_25630	COG2212	antiporter activity
RvVAT039_25640	COG1863	multisubunit Na H antiporter MnhE subunit
RvVAT039_25660	COG1006	Multisubunit Na H antiporter MnhC subunit
RvVAT039_25670	COG2111	Na H antiporter
RvVAT039_25690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RvVAT039_25760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_25770	COG0577	efflux transmembrane transporter activity
RvVAT039_25770	COG1136	(ABC) transporter
RvVAT039_25810	COG2166	iron-sulfur cluster assembly
RvVAT039_25830	COG2205	protein histidine kinase activity
RvVAT039_25860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_25970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RvVAT039_25980	COG2983	Belongs to the UPF0260 family
RvVAT039_26010	COG0789	Transcriptional regulator
RvVAT039_26060	COG4695	Portal protein
RvVAT039_26260	COG0745	RESPONSE REGULATOR receiver
RvVAT039_26270	COG2205	protein histidine kinase activity
RvVAT039_26280	COG4520	surface antigen
RvVAT039_26290	COG4235	cytochrome complex assembly
RvVAT039_26300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
RvVAT039_26310	COG1138	Cytochrome C-type biogenesis protein
RvVAT039_26320	COG3088	subunit of a heme lyase
RvVAT039_26340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RvVAT039_26350	COG0745	RESPONSE REGULATOR receiver
RvVAT039_26360	COG2205	protein histidine kinase activity
RvVAT039_26370	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RvVAT039_26380	COG2202	Pas domain
RvVAT039_26380	COG2205	protein histidine kinase activity
RvVAT039_26390	COG0308	aminopeptidase N
RvVAT039_26400	COG3290	protein histidine kinase activity
RvVAT039_26400	COG0840	transmembrane signaling receptor activity
RvVAT039_26470	COG0443	Heat shock 70 kDa protein
RvVAT039_26500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_26530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_26540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_26550	COG2239	Acts as a magnesium transporter
RvVAT039_26560	COG2814	Major facilitator Superfamily
RvVAT039_26590	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_26600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_26610	COG0601	transmembrane transport
RvVAT039_26620	COG4166	transmembrane transport
RvVAT039_26630	COG0174	glutamine synthetase
RvVAT039_26660	COG1695	Transcriptional regulator
RvVAT039_26680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RvVAT039_26690	COG0463	Glycosyl transferase, family 2
RvVAT039_26710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RvVAT039_26730	COG0625	glutathione transferase activity
RvVAT039_26760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RvVAT039_26830	COG0741	lytic transglycosylase activity
RvVAT039_26840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_26850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RvVAT039_26870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RvVAT039_26870	COG2169	Transcriptional regulator
RvVAT039_26880	COG0840	transmembrane signaling receptor activity
RvVAT039_26900	COG1758	RNA polymerase activity
RvVAT039_26930	COG0681	Belongs to the peptidase S26 family
RvVAT039_26940	COG0571	ribonuclease III activity
RvVAT039_26950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RvVAT039_26960	COG3180	Ammonia monooxygenase
RvVAT039_26970	COG1381	Involved in DNA repair and RecF pathway recombination
RvVAT039_27000	COG1418	mRNA catabolic process
RvVAT039_27030	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
RvVAT039_27040	COG0354	folic acid binding
RvVAT039_27080	COG1051	belongs to the nudix hydrolase family
RvVAT039_27110	COG1183	phosphatidylcholine synthase activity
RvVAT039_27120	COG0688	phosphatidylethanolamine metabolic process
RvVAT039_27130	COG5265	(ABC) transporter
RvVAT039_27140	COG2823	Periplasmic or secreted lipoprotein
RvVAT039_27140	COG1652	LysM domain
RvVAT039_27160	COG2962	Rard protein
RvVAT039_27170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RvVAT039_27250	COG0215	cysteine-tRNA ligase activity
RvVAT039_27260	COG5434	Belongs to the glycosyl hydrolase 28 family
RvVAT039_27270	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RvVAT039_27280	COG1088	dTDP-glucose 4,6-dehydratase activity
RvVAT039_27290	COG1091	dTDP-4-dehydrorhamnose reductase activity
RvVAT039_27300	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RvVAT039_27330	COG4221	oxidoreductase activity
RvVAT039_27340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RvVAT039_27350	COG1286	toxin biosynthetic process
RvVAT039_27360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RvVAT039_27370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RvVAT039_27400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RvVAT039_27410	COG2207	Transcriptional regulator
RvVAT039_27410	COG1917	Cupin 2, conserved barrel domain protein
RvVAT039_27420	COG0765	amino acid transport
RvVAT039_27430	COG0765	amino acid transport
RvVAT039_27460	COG0305	Participates in initiation and elongation during chromosome replication
RvVAT039_27470	COG0359	binds to the 23S rRNA
RvVAT039_27490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RvVAT039_27500	COG0360	Binds together with S18 to 16S ribosomal RNA
RvVAT039_27540	COG0667	Aldo Keto reductase
RvVAT039_27550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RvVAT039_27570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_27580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RvVAT039_27590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RvVAT039_27600	COG1561	YicC-like family, N-terminal region
RvVAT039_27610	COG0194	GDP metabolic process
RvVAT039_27620	COG0500	methyltransferase
RvVAT039_27630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RvVAT039_27640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RvVAT039_27660	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RvVAT039_27690	COG0671	phosphoesterase, PA-phosphatase related
RvVAT039_27700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RvVAT039_27730	COG1505	serine-type exopeptidase activity
RvVAT039_27740	COG0488	(ABC) transporter
RvVAT039_27760	COG0105	UTP biosynthetic process
RvVAT039_27770	COG0314	molybdopterin synthase activity
RvVAT039_27790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RvVAT039_27800	COG0322	excinuclease ABC activity
RvVAT039_27810	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_27830	COG0625	glutathione transferase activity
RvVAT039_27840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RvVAT039_27850	COG0243	molybdopterin cofactor binding
RvVAT039_27860	COG0494	nUDIX hydrolase
RvVAT039_27870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RvVAT039_27870	COG3453	Protein conserved in bacteria
RvVAT039_27880	COG0640	Transcriptional regulator
RvVAT039_27910	COG0730	response to heat
RvVAT039_27920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RvVAT039_27930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RvVAT039_27940	COG0628	permease
RvVAT039_27960	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RvVAT039_27970	COG0248	Ppx GppA phosphatase
RvVAT039_27980	COG1321	iron dependent repressor
RvVAT039_27990	COG1914	H( )-stimulated, divalent metal cation uptake system
RvVAT039_28030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RvVAT039_28040	COG2132	Multicopper oxidase
RvVAT039_28060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RvVAT039_28090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RvVAT039_28100	COG5001	Diguanylate cyclase
RvVAT039_28100	COG3300	MHYT domain
RvVAT039_28120	COG2203	Gaf domain
RvVAT039_28120	COG2200	EAL domain
RvVAT039_28120	COG2199	diguanylate cyclase activity
RvVAT039_28130	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RvVAT039_28150	COG3293	Transposase
RvVAT039_28170	COG0113	porphobilinogen synthase activity
RvVAT039_28210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RvVAT039_28220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RvVAT039_28230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RvVAT039_28230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RvVAT039_28260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RvVAT039_28270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RvVAT039_28280	COG2814	Major facilitator Superfamily
RvVAT039_28290	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RvVAT039_28330	COG0416	fatty acid biosynthetic process
RvVAT039_28340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RvVAT039_28350	COG0776	regulation of translation
RvVAT039_28500	COG1612	heme a metabolic process
RvVAT039_28510	COG3384	dioxygenase
RvVAT039_28540	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RvVAT039_28550	COG0010	Belongs to the arginase family
RvVAT039_28580	COG2329	Antibiotic biosynthesis monooxygenase
RvVAT039_28590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RvVAT039_28600	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RvVAT039_28610	COG1832	CoA-binding protein
RvVAT039_28630	COG1832	CoA-binding protein
RvVAT039_28650	COG1408	metallophosphoesterase
RvVAT039_28670	COG2124	cytochrome p450
RvVAT039_28690	COG0740	serine-type endopeptidase activity
RvVAT039_28700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RvVAT039_28710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RvVAT039_28760	COG1024	Enoyl-CoA hydratase
RvVAT039_28770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_28780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_28790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_28800	COG0649	NAD binding
RvVAT039_28820	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
RvVAT039_28830	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RvVAT039_28840	COG0052	Belongs to the universal ribosomal protein uS2 family
RvVAT039_28860	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RvVAT039_28870	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RvVAT039_28890	COG0713	ATP synthesis coupled electron transport
RvVAT039_28920	COG1007	ATP synthesis coupled electron transport
RvVAT039_28950	COG0346	lactoylglutathione lyase activity
RvVAT039_28960	COG0251	oxidation-reduction process
RvVAT039_28990	COG0442	prolyl-tRNA aminoacylation
RvVAT039_29010	COG1136	(ABC) transporter
RvVAT039_29040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RvVAT039_29070	COG0784	Response regulator, receiver
RvVAT039_29090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RvVAT039_29100	COG0477	Major facilitator Superfamily
RvVAT039_29120	COG0557	exoribonuclease II activity
RvVAT039_29130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RvVAT039_29150	COG0758	DNA mediated transformation
RvVAT039_29160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RvVAT039_29180	COG0540	Belongs to the ATCase OTCase family
RvVAT039_29190	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_29230	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RvVAT039_29240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RvVAT039_29250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RvVAT039_29260	COG0154	amidase activity
RvVAT039_29290	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RvVAT039_29300	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RvVAT039_29300	COG3952	Lipid A Biosynthesis
RvVAT039_29310	COG0463	Glycosyl transferase, family 2
RvVAT039_29330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RvVAT039_29370	COG4765	Protein conserved in bacteria
RvVAT039_29380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RvVAT039_29400	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_29410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RvVAT039_29420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RvVAT039_29430	COG0436	Aminotransferase
RvVAT039_29450	COG1530	ribonuclease E activity
RvVAT039_29450	COG1530	ribonuclease E activity
RvVAT039_29460	COG0860	N-Acetylmuramoyl-L-alanine amidase
RvVAT039_29470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RvVAT039_29490	COG0284	orotidine-5'-phosphate decarboxylase activity
RvVAT039_29510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RvVAT039_29540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RvVAT039_29550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RvVAT039_29590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RvVAT039_29610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RvVAT039_29620	COG0081	regulation of translation
RvVAT039_29630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RvVAT039_29640	COG0222	ribosome binding
RvVAT039_29650	COG0085	RNA polymerase activity
RvVAT039_29660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RvVAT039_29680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RvVAT039_29690	COG0049	tRNA binding
RvVAT039_29700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RvVAT039_29710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RvVAT039_29720	COG0051	transcription antitermination factor activity, RNA binding
RvVAT039_29730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RvVAT039_29740	COG0088	Forms part of the polypeptide exit tunnel
RvVAT039_29750	COG0089	rRNA binding
RvVAT039_29760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RvVAT039_29770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RvVAT039_29780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RvVAT039_29790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RvVAT039_29800	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RvVAT039_29810	COG0255	Belongs to the universal ribosomal protein uL29 family
RvVAT039_29820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RvVAT039_29830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RvVAT039_29840	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RvVAT039_29850	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RvVAT039_29860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RvVAT039_29870	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RvVAT039_29880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RvVAT039_29890	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RvVAT039_29900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RvVAT039_29910	COG1841	ribosomal large subunit assembly
RvVAT039_29920	COG0200	Binds to the 23S rRNA
RvVAT039_29930	COG0201	protein transport
RvVAT039_29940	COG0563	adenylate kinase activity
RvVAT039_29950	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RvVAT039_29960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RvVAT039_29970	COG0202	RNA polymerase activity
RvVAT039_29980	COG0203	ribosomal protein L17
RvVAT039_30010	COG2897	thiosulfate sulfurtransferase activity
RvVAT039_30030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RvVAT039_30040	COG0415	Belongs to the DNA photolyase family
RvVAT039_30060	COG0739	heme binding
RvVAT039_30070	COG2833	Protein of unknown function (DUF455)
RvVAT039_30080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RvVAT039_30130	COG0280	phosphate acetyltransferase
RvVAT039_30130	COG0281	malic enzyme
RvVAT039_30150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RvVAT039_30160	COG1127	ABC transporter
RvVAT039_30180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RvVAT039_30180	COG3218	ABC-type transport auxiliary lipoprotein component
RvVAT039_30190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RvVAT039_30230	COG0047	phosphoribosylformylglycinamidine synthase activity
RvVAT039_30240	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RvVAT039_30250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RvVAT039_30280	COG3706	GGDEF domain
RvVAT039_30300	COG0538	isocitrate dehydrogenase activity
RvVAT039_30310	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RvVAT039_30320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RvVAT039_30340	COG1253	flavin adenine dinucleotide binding
RvVAT039_30360	COG2755	lipolytic protein G-D-S-L family
RvVAT039_30360	COG0657	acetylesterase activity
RvVAT039_30370	COG2195	Cleaves the N-terminal amino acid of tripeptides
RvVAT039_30400	COG0861	Integral membrane protein TerC family
RvVAT039_30420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RvVAT039_30430	COG2066	Belongs to the glutaminase family
RvVAT039_30450	COG0037	tRNA processing
RvVAT039_30460	COG0483	inositol monophosphate 1-phosphatase activity
RvVAT039_30470	COG0483	inositol monophosphate 1-phosphatase activity
RvVAT039_30480	COG2814	Major facilitator Superfamily
RvVAT039_30490	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RvVAT039_30520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RvVAT039_30530	COG0484	heat shock protein binding
RvVAT039_30550	COG0321	lipoyl(octanoyl) transferase activity
RvVAT039_30660	COG0250	Participates in transcription elongation, termination and antitermination
RvVAT039_30820	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RvVAT039_30830	COG1091	dTDP-4-dehydrorhamnose reductase activity
RvVAT039_30840	COG1088	dTDP-glucose 4,6-dehydratase activity
RvVAT039_30850	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RvVAT039_31060	COG2801	Transposase and inactivated derivatives
RvVAT039_31120	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RvVAT039_31130	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RvVAT039_31190	COG0242	peptide deformylase activity
RvVAT039_31210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RvVAT039_31220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RvVAT039_31230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RvVAT039_31240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RvVAT039_31250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RvVAT039_31300	COG0823	Involved in the tonB-independent uptake of proteins
RvVAT039_31310	COG0778	Nitroreductase
RvVAT039_31330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RvVAT039_31340	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RvVAT039_31370	COG2202	Pas domain
RvVAT039_31370	COG2205	protein histidine kinase activity
RvVAT039_31390	COG1573	uracil-dna glycosylase
RvVAT039_31400	COG1522	sequence-specific DNA binding
RvVAT039_31410	COG2084	Dehydrogenase
RvVAT039_31420	COG2267	carboxylic ester hydrolase activity
RvVAT039_31440	COG5425	PFAM Usg family protein
RvVAT039_31500	COG1763	Mo-molybdopterin cofactor biosynthetic process
RvVAT039_31510	COG0746	molybdenum cofactor guanylyltransferase activity
RvVAT039_31530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RvVAT039_31550	COG3706	GGDEF domain
RvVAT039_31570	COG0114	fumarate hydratase activity
RvVAT039_31580	COG2989	Protein conserved in bacteria
RvVAT039_31590	COG0546	phosphoglycolate phosphatase activity
RvVAT039_31600	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RvVAT039_31630	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RvVAT039_31700	COG2203	Gaf domain
RvVAT039_31700	COG5001	Diguanylate cyclase
RvVAT039_31700	COG3706	GGDEF domain
RvVAT039_31700	COG4251	negative regulation of phosphorylation
RvVAT039_31710	COG0556	nucleotide-excision repair
RvVAT039_31750	COG3161	chorismate lyase activity
RvVAT039_31770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RvVAT039_31780	COG0148	phosphopyruvate hydratase activity
RvVAT039_31800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RvVAT039_31810	COG0508	dehydrogenase complex catalyzes the overall conversion of
RvVAT039_31810	COG0022	dehydrogenase e1 component
RvVAT039_31820	COG0508	dehydrogenase complex catalyzes the overall conversion of
RvVAT039_31850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RvVAT039_31870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RvVAT039_31910	COG0477	Major facilitator Superfamily
RvVAT039_31920	COG2867	negative regulation of translational initiation
RvVAT039_31930	COG1058	Belongs to the CinA family
RvVAT039_31930	COG1546	Belongs to the CinA family
RvVAT039_31940	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RvVAT039_31940	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RvVAT039_31960	COG3852	Histidine kinase
RvVAT039_31970	COG2204	response regulator
RvVAT039_31980	COG5000	phosphorelay sensor kinase activity
RvVAT039_31990	COG2204	response regulator
RvVAT039_32000	COG1923	regulation of RNA biosynthetic process
RvVAT039_32010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RvVAT039_32030	COG3956	TIGRFAM MazG family protein
RvVAT039_32050	COG1648	precorrin-2 dehydrogenase activity
RvVAT039_32050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RvVAT039_32100	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_32120	COG1686	Belongs to the peptidase S11 family
RvVAT039_32130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RvVAT039_32150	COG0730	response to heat
RvVAT039_32160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RvVAT039_32170	COG0084	hydrolase, TatD family'
RvVAT039_32180	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RvVAT039_32180	COG0321	lipoyl(octanoyl) transferase activity
RvVAT039_32200	COG0785	Cytochrome C biogenesis protein
RvVAT039_32210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_32220	COG1183	phosphatidylcholine synthase activity
RvVAT039_32280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RvVAT039_32290	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RvVAT039_32330	COG1177	transmembrane transport
RvVAT039_32340	COG4149	molybdate abc transporter
RvVAT039_32350	COG3842	ATPase activity
RvVAT039_32370	COG1940	carbohydrate kinase activity
RvVAT039_32380	COG0523	cobalamin synthesis protein
RvVAT039_32410	COG1121	(ABC) transporter
RvVAT039_32420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RvVAT039_32430	COG0735	belongs to the Fur family
RvVAT039_32470	COG1686	Belongs to the peptidase S11 family
RvVAT039_32540	COG1752	Esterase of the alpha-beta hydrolase superfamily
RvVAT039_32550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RvVAT039_32560	COG0302	gtp cyclohydrolase
RvVAT039_32580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RvVAT039_32590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RvVAT039_32620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RvVAT039_32630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RvVAT039_32720	COG0187	DNA topoisomerase II activity
RvVAT039_32750	COG0149	triose-phosphate isomerase activity
RvVAT039_32770	COG0504	CTP synthase activity
RvVAT039_32820	COG0633	Ferredoxin
RvVAT039_32840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RvVAT039_32920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RvVAT039_32920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RvVAT039_32930	COG0509	glycine decarboxylation via glycine cleavage system
RvVAT039_32940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_32980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RvVAT039_32990	COG0564	pseudouridine synthase activity
RvVAT039_33000	COG0546	phosphoglycolate phosphatase activity
RvVAT039_33030	COG0477	Major facilitator Superfamily
RvVAT039_33060	COG2003	Belongs to the UPF0758 family
RvVAT039_33070	COG0024	Methionine aminopeptidase
RvVAT039_33080	COG0583	DNA-binding transcription factor activity
RvVAT039_33090	COG2855	membrane
RvVAT039_33100	COG1489	DNA binding
RvVAT039_33110	COG3243	poly(R)-hydroxyalkanoic acid synthase
RvVAT039_33130	COG0436	Aminotransferase
RvVAT039_33150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RvVAT039_33170	COG0346	lactoylglutathione lyase activity
RvVAT039_33180	COG1278	Cold shock
RvVAT039_33220	COG0587	DNA-directed DNA polymerase activity
RvVAT039_33280	COG3293	Transposase
RvVAT039_33320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RvVAT039_33340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RvVAT039_33350	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_33370	COG0697	spore germination
RvVAT039_33420	COG0174	glutamine synthetase
RvVAT039_33430	COG0347	Belongs to the P(II) protein family
RvVAT039_33440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RvVAT039_33440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RvVAT039_33470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RvVAT039_33480	COG0629	single-stranded DNA binding
RvVAT039_33500	COG2095	MarC family integral membrane protein
RvVAT039_33510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RvVAT039_33520	COG2217	Heavy metal translocating P-type atpase
RvVAT039_33570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RvVAT039_33600	COG1653	transport
RvVAT039_33610	COG1175	transmembrane transport
RvVAT039_33620	COG0395	ABC-type sugar transport system, permease component
RvVAT039_33630	COG3842	ATPase activity
RvVAT039_33670	COG0667	Aldo Keto reductase
RvVAT039_33680	COG3507	Belongs to the glycosyl hydrolase 43 family
RvVAT039_33710	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RvVAT039_33720	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RvVAT039_33730	COG0129	dihydroxy-acid dehydratase activity
RvVAT039_33770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RvVAT039_33820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_33850	COG0513	Belongs to the DEAD box helicase family
RvVAT039_33870	COG2945	thiolester hydrolase activity
RvVAT039_33880	COG1104	cysteine desulfurase activity
RvVAT039_33890	COG0719	Fe-S assembly protein
RvVAT039_33910	COG0396	ATPase activity
RvVAT039_33920	COG0719	Fe-S assembly protein
RvVAT039_33940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RvVAT039_33950	COG2151	metal-sulfur cluster biosynthetic enzyme
RvVAT039_33980	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RvVAT039_34010	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RvVAT039_34020	COG0343	queuine tRNA-ribosyltransferase activity
RvVAT039_34060	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RvVAT039_34070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_34080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RvVAT039_34090	COG2080	2 iron, 2 sulfur cluster binding
RvVAT039_34150	COG2062	phosphohistidine phosphatase, SixA
RvVAT039_34160	COG3106	COG3106 Predicted ATPase
RvVAT039_34170	COG3768	UPF0283 membrane protein
RvVAT039_34200	COG0436	Aminotransferase
RvVAT039_34220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RvVAT039_34230	COG0544	peptidyl-prolyl cis-trans isomerase activity
RvVAT039_34280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RvVAT039_34290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RvVAT039_34320	COG0252	asparaginase activity
RvVAT039_34340	COG0737	Belongs to the 5'-nucleotidase family
RvVAT039_34360	COG0463	Glycosyl transferase, family 2
RvVAT039_34380	COG4303	Ethanolamine ammonia lyase large subunit
RvVAT039_34390	COG4302	ethanolamine ammonia-lyase activity
RvVAT039_34400	COG1192	Involved in chromosome partitioning
RvVAT039_34410	COG1475	DNA binding
RvVAT039_34420	COG0640	Transcriptional regulator
RvVAT039_34430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RvVAT039_34440	COG0392	lysyltransferase activity
RvVAT039_34450	COG3257	ureidoglycine aminohydrolase activity
RvVAT039_34500	COG1522	sequence-specific DNA binding
RvVAT039_34550	COG2040	homocysteine
RvVAT039_34560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_34580	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RvVAT039_34590	COG1473	amidohydrolase
RvVAT039_34610	COG0297	glycogen (starch) synthase activity
RvVAT039_34660	COG1063	alcohol dehydrogenase
RvVAT039_34670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RvVAT039_34680	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_34690	COG3265	gluconokinase activity
RvVAT039_34700	COG2084	Dehydrogenase
RvVAT039_34720	COG1609	Transcriptional regulator
RvVAT039_34750	COG1129	ABC transporter
RvVAT039_34780	COG1879	ABC-type sugar transport system periplasmic component
RvVAT039_34790	COG1129	ABC transporter
RvVAT039_34800	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_34810	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_34820	COG2186	Transcriptional regulator
RvVAT039_34830	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_34840	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_34860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_34880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_34930	COG0778	Nitroreductase
RvVAT039_34960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RvVAT039_34970	COG0659	secondary active sulfate transmembrane transporter activity
RvVAT039_35110	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_35130	COG1802	Transcriptional regulator
RvVAT039_35140	COG0747	negative chemotaxis
RvVAT039_35150	COG2723	6-phospho-beta-galactosidase activity
RvVAT039_35160	COG0601	transmembrane transport
RvVAT039_35180	COG3964	amidohydrolase
RvVAT039_35210	COG1921	L-seryl-tRNASec selenium transferase activity
RvVAT039_35230	COG5001	Diguanylate cyclase
RvVAT039_35230	COG2203	Gaf domain
RvVAT039_35230	COG4251	negative regulation of phosphorylation
RvVAT039_35230	COG3706	GGDEF domain
RvVAT039_35270	COG2080	2 iron, 2 sulfur cluster binding
RvVAT039_35280	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RvVAT039_35290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_35340	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_35360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RvVAT039_35370	COG1486	melibiose metabolic process
RvVAT039_35380	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_35390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_35400	COG0601	transmembrane transport
RvVAT039_35410	COG0747	negative chemotaxis
RvVAT039_35420	COG1486	melibiose metabolic process
RvVAT039_35430	COG2207	Transcriptional regulator
RvVAT039_35430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RvVAT039_35460	COG0745	RESPONSE REGULATOR receiver
RvVAT039_35490	COG1063	alcohol dehydrogenase
RvVAT039_35500	COG4948	Mandelate Racemase Muconate Lactonizing
RvVAT039_35540	COG4214	carbohydrate transport
RvVAT039_35550	COG1129	ABC transporter
RvVAT039_35580	COG1175	transmembrane transport
RvVAT039_35590	COG0395	ABC-type sugar transport system, permease component
RvVAT039_35630	COG1609	Transcriptional regulator
RvVAT039_35660	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_35690	COG0840	transmembrane signaling receptor activity
RvVAT039_35690	COG2972	Histidine kinase
RvVAT039_35740	COG0667	Aldo Keto reductase
RvVAT039_35770	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_35790	COG4213	ABC transporter substrate-binding protein
RvVAT039_35820	COG1129	ABC transporter
RvVAT039_35830	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_35840	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_35870	COG0765	amino acid transport
RvVAT039_35880	COG1126	abc transporter atp-binding protein
RvVAT039_35890	COG2079	MmgE PrpD family protein
RvVAT039_35900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_35930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_35960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_35980	COG0747	negative chemotaxis
RvVAT039_36010	COG2197	response regulator
RvVAT039_36020	COG3850	Histidine kinase
RvVAT039_36020	COG5002	protein histidine kinase activity
RvVAT039_36030	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RvVAT039_36050	COG2731	YhcH YjgK YiaL family protein
RvVAT039_36060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_36070	COG2271	Major facilitator Superfamily
RvVAT039_36080	COG1609	Transcriptional regulator
RvVAT039_36090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_36100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_36110	COG1473	amidohydrolase
RvVAT039_36160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_36170	COG2205	protein histidine kinase activity
RvVAT039_36180	COG0745	RESPONSE REGULATOR receiver
RvVAT039_36200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_36240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_36260	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_36280	COG1309	transcriptional regulator
RvVAT039_36350	COG2207	Transcriptional regulator
RvVAT039_36370	COG0235	Class ii aldolase
RvVAT039_36410	COG4221	oxidoreductase activity
RvVAT039_36470	COG1595	DNA-templated transcription, initiation
RvVAT039_36490	COG2824	Alkylphosphonate utilization operon protein PhnA
RvVAT039_36540	COG3833	ABC-type maltose transport systems, permease component
RvVAT039_36550	COG3842	ATPase activity
RvVAT039_36560	COG0584	glycerophosphoryl diester phosphodiesterase
RvVAT039_36640	COG1320	monovalent cation:proton antiporter activity
RvVAT039_36650	COG2212	antiporter activity
RvVAT039_36660	COG1863	multisubunit Na H antiporter MnhE subunit
RvVAT039_36670	COG0651	ATP synthesis coupled electron transport
RvVAT039_36680	COG1006	Multisubunit Na H antiporter MnhC subunit
RvVAT039_36690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RvVAT039_36690	COG2111	Na H antiporter
RvVAT039_36750	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_36760	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_36790	COG2072	flavoprotein involved in K transport
RvVAT039_36800	COG1177	transmembrane transport
RvVAT039_36810	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_36820	COG3842	ATPase activity
RvVAT039_36830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RvVAT039_36840	COG0583	DNA-binding transcription factor activity
RvVAT039_36910	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_36960	COG0601	transmembrane transport
RvVAT039_36970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_37010	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_37020	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_37030	COG1846	Transcriptional regulator
RvVAT039_37100	COG0625	glutathione transferase activity
RvVAT039_37140	COG2133	pyrroloquinoline quinone binding
RvVAT039_37160	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_37190	COG0753	catalase activity
RvVAT039_37200	COG0306	phosphate transporter
RvVAT039_37210	COG3842	ATPase activity
RvVAT039_37220	COG1175	transmembrane transport
RvVAT039_37230	COG0395	ABC-type sugar transport system, permease component
RvVAT039_37280	COG3684	Belongs to the aldolase LacD family
RvVAT039_37290	COG2390	Transcriptional regulator
RvVAT039_37330	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_37340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_37350	COG0626	cystathionine gamma-synthase activity
RvVAT039_37360	COG1725	Transcriptional regulator
RvVAT039_37370	COG0747	negative chemotaxis
RvVAT039_37410	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_37420	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_37430	COG0006	proline dipeptidase activity
RvVAT039_37450	COG0747	negative chemotaxis
RvVAT039_37480	COG0405	Gamma-glutamyltransferase
RvVAT039_37500	COG0754	glutathionylspermidine amidase activity
RvVAT039_37520	COG3766	membrane
RvVAT039_37540	COG3789	protein conserved in bacteria
RvVAT039_37570	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_37590	COG1802	Transcriptional regulator
RvVAT039_37610	COG0601	transmembrane transport
RvVAT039_37670	COG0747	negative chemotaxis
RvVAT039_37690	COG2205	protein histidine kinase activity
RvVAT039_37700	COG2197	response regulator
RvVAT039_37710	COG4585	Histidine kinase
RvVAT039_37740	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RvVAT039_37750	COG4208	sulfate ABC transporter
RvVAT039_37760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RvVAT039_37770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RvVAT039_37780	COG1609	Transcriptional regulator
RvVAT039_37790	COG0673	inositol 2-dehydrogenase activity
RvVAT039_37810	COG1653	transport
RvVAT039_37820	COG1175	transmembrane transport
RvVAT039_37830	COG0395	ABC-type sugar transport system, permease component
RvVAT039_37840	COG3842	ATPase activity
RvVAT039_37860	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RvVAT039_37890	COG0583	DNA-binding transcription factor activity
RvVAT039_37900	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_37910	COG3250	beta-galactosidase activity
RvVAT039_37920	COG1940	carbohydrate kinase activity
RvVAT039_37930	COG2116	formate transmembrane transporter activity
RvVAT039_37940	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_38030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RvVAT039_38040	COG0583	DNA-binding transcription factor activity
RvVAT039_38070	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RvVAT039_38080	COG0402	S-adenosylhomocysteine deaminase activity
RvVAT039_38100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RvVAT039_38110	COG2080	2 iron, 2 sulfur cluster binding
RvVAT039_38120	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_38150	COG2186	Transcriptional regulator
RvVAT039_38160	COG1304	FMN binding
RvVAT039_38180	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_38270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RvVAT039_38280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RvVAT039_38290	COG1126	abc transporter atp-binding protein
RvVAT039_38300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_38310	COG0765	amino acid transport
RvVAT039_38320	COG0765	amino acid transport
RvVAT039_38340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RvVAT039_38360	COG1764	response to oxidative stress
RvVAT039_38390	COG1116	anion transmembrane transporter activity
RvVAT039_38400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_38410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_38420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_38430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_38440	COG1959	2 iron, 2 sulfur cluster binding
RvVAT039_38490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RvVAT039_38560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_38600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_38620	COG1116	anion transmembrane transporter activity
RvVAT039_38650	COG4191	Histidine kinase
RvVAT039_38660	COG4566	intracellular signal transduction
RvVAT039_38680	COG3842	ATPase activity
RvVAT039_38690	COG0395	ABC-type sugar transport system, permease component
RvVAT039_38700	COG1175	transmembrane transport
RvVAT039_38770	COG1940	carbohydrate kinase activity
RvVAT039_38780	COG0747	negative chemotaxis
RvVAT039_38790	COG0601	transmembrane transport
RvVAT039_38800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_38820	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_38830	COG0745	RESPONSE REGULATOR receiver
RvVAT039_38840	COG2205	protein histidine kinase activity
RvVAT039_38860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_38880	COG2076	Multidrug Resistance protein
RvVAT039_38920	COG2076	Multidrug Resistance protein
RvVAT039_38950	COG1215	transferase activity, transferring glycosyl groups
RvVAT039_38980	COG2202	Pas domain
RvVAT039_38980	COG3920	Histidine kinase
RvVAT039_39000	COG0784	Response regulator, receiver
RvVAT039_39020	COG1162	GTPase activity
RvVAT039_39030	COG4191	Histidine kinase
RvVAT039_39030	COG0784	Response regulator, receiver
RvVAT039_39040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_39050	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RvVAT039_39050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_39070	COG1126	abc transporter atp-binding protein
RvVAT039_39080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_39100	COG0840	transmembrane signaling receptor activity
RvVAT039_39100	COG2972	Histidine kinase
RvVAT039_39110	COG0835	chemotaxis
RvVAT039_39130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_39160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_39180	COG0789	Transcriptional regulator
RvVAT039_39190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RvVAT039_39200	COG0366	Alpha amylase catalytic
RvVAT039_39210	COG0366	Alpha amylase catalytic
RvVAT039_39220	COG1640	4-alpha-glucanotransferase
RvVAT039_39230	COG1278	Cold shock
RvVAT039_39240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RvVAT039_39260	COG0673	inositol 2-dehydrogenase activity
RvVAT039_39280	COG1802	Transcriptional regulator
RvVAT039_39290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_39310	COG0673	inositol 2-dehydrogenase activity
RvVAT039_39330	COG1175	transmembrane transport
RvVAT039_39340	COG0395	ABC-type sugar transport system, permease component
RvVAT039_39360	COG0673	inositol 2-dehydrogenase activity
RvVAT039_39380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RvVAT039_39400	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_39420	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
RvVAT039_39430	COG3920	Histidine kinase
RvVAT039_39460	COG3685	Protein conserved in bacteria
RvVAT039_39520	COG5001	Diguanylate cyclase
RvVAT039_39530	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RvVAT039_39570	COG1132	(ABC) transporter
RvVAT039_39580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_39580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RvVAT039_39610	COG3842	ATPase activity
RvVAT039_39620	COG3833	ABC-type maltose transport systems, permease component
RvVAT039_39650	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RvVAT039_39710	COG3321	synthase
RvVAT039_39710	COG0604	alcohol dehydrogenase
RvVAT039_39750	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_39770	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_39800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_39810	COG0747	negative chemotaxis
RvVAT039_39850	COG0583	DNA-binding transcription factor activity
RvVAT039_39860	COG0747	negative chemotaxis
RvVAT039_39880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_39910	COG0154	amidase activity
RvVAT039_39940	COG1335	isochorismatase
RvVAT039_39950	COG1129	ABC transporter
RvVAT039_39980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RvVAT039_40030	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_40040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_40050	COG0601	transmembrane transport
RvVAT039_40110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_40130	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_40150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_40160	COG1309	transcriptional regulator
RvVAT039_40190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RvVAT039_40220	COG4770	biotin carboxylase activity
RvVAT039_40250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RvVAT039_40250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RvVAT039_40300	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_40310	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_40320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_40320	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RvVAT039_40330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RvVAT039_40350	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_40360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_40370	COG0601	transmembrane transport
RvVAT039_40380	COG0747	negative chemotaxis
RvVAT039_40390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_40400	COG2186	Transcriptional regulator
RvVAT039_40420	COG0640	Transcriptional regulator
RvVAT039_40440	COG3842	ATPase activity
RvVAT039_40450	COG1175	transmembrane transport
RvVAT039_40460	COG0395	ABC-type sugar transport system, permease component
RvVAT039_40480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RvVAT039_40500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_40510	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_40520	COG2084	Dehydrogenase
RvVAT039_40540	COG3386	PFAM SMP-30 Gluconolaconase
RvVAT039_40560	COG2771	luxR family
RvVAT039_40580	COG0626	cystathionine gamma-synthase activity
RvVAT039_40610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RvVAT039_40680	COG1175	transmembrane transport
RvVAT039_40690	COG0395	ABC-type sugar transport system, permease component
RvVAT039_40710	COG3842	ATPase activity
RvVAT039_40740	COG0446	pyridine nucleotide-disulphide oxidoreductase
RvVAT039_40740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RvVAT039_40750	COG4311	Sarcosine oxidase, delta subunit
RvVAT039_40760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_40770	COG4977	sequence-specific DNA binding
RvVAT039_40790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RvVAT039_40800	COG2218	PFAM glutamate synthase alpha subunit domain protein
RvVAT039_40810	COG0069	glutamate synthase activity
RvVAT039_40840	COG1304	FMN binding
RvVAT039_40870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RvVAT039_40890	COG3842	ATPase activity
RvVAT039_40900	COG1175	transmembrane transport
RvVAT039_40910	COG0395	ABC-type sugar transport system, permease component
RvVAT039_40920	COG1609	Transcriptional regulator
RvVAT039_40950	COG0412	Dienelactone hydrolase
RvVAT039_40970	COG0583	DNA-binding transcription factor activity
RvVAT039_40990	COG0583	DNA-binding transcription factor activity
RvVAT039_41040	COG0306	phosphate transporter
RvVAT039_41070	COG0277	FAD linked oxidase domain protein
RvVAT039_41080	COG0277	FAD linked oxidase domain protein
RvVAT039_41100	COG0247	lactate metabolic process
RvVAT039_41120	COG0625	glutathione transferase activity
RvVAT039_41140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RvVAT039_41150	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
RvVAT039_41180	COG2852	Protein conserved in bacteria
RvVAT039_41190	COG0124	histidyl-tRNA synthetase
RvVAT039_41260	COG2818	Glycosylase
RvVAT039_41280	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_41280	COG1388	LysM domain
RvVAT039_41290	COG1376	ErfK ybiS ycfS ynhG family protein
RvVAT039_41300	COG2909	trisaccharide binding
RvVAT039_41320	COG2137	regulation of response to DNA damage stimulus
RvVAT039_41330	COG2130	NADP-dependent
RvVAT039_41360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RvVAT039_41410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_41430	COG0196	riboflavin kinase activity
RvVAT039_41450	COG2059	Chromate
RvVAT039_41460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RvVAT039_41470	COG0459	protein refolding
RvVAT039_41510	COG3842	ATPase activity
RvVAT039_41530	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_41540	COG1177	transmembrane transport
RvVAT039_41550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RvVAT039_41560	COG0019	diaminopimelate decarboxylase activity
RvVAT039_41580	COG4770	biotin carboxylase activity
RvVAT039_41590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_41600	COG4336	lyase activity
RvVAT039_41610	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_41620	COG1914	H( )-stimulated, divalent metal cation uptake system
RvVAT039_41630	COG1802	Transcriptional regulator
RvVAT039_41640	COG1522	sequence-specific DNA binding
RvVAT039_41650	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RvVAT039_41680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RvVAT039_41700	COG0583	DNA-binding transcription factor activity
RvVAT039_41710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_41720	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_41730	COG0439	Biotin carboxylase
RvVAT039_41750	COG1984	allophanate hydrolase subunit 2
RvVAT039_41770	COG3842	ATPase activity
RvVAT039_41780	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_41800	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_41810	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_41830	COG3842	ATPase activity
RvVAT039_41840	COG0726	polysaccharide deacetylase
RvVAT039_41860	COG0523	cobalamin synthesis protein
RvVAT039_41890	COG1522	sequence-specific DNA binding
RvVAT039_41910	COG0659	secondary active sulfate transmembrane transporter activity
RvVAT039_41940	COG0243	molybdopterin cofactor binding
RvVAT039_41960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RvVAT039_41970	COG1116	anion transmembrane transporter activity
RvVAT039_41980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_41990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_42000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_42010	COG3707	response regulator
RvVAT039_42060	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_42070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RvVAT039_42100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_42130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RvVAT039_42160	COG2022	thiamine diphosphate biosynthetic process
RvVAT039_42460	COG0640	Transcriptional regulator
RvVAT039_42470	COG0798	PFAM Bile acid sodium symporter
RvVAT039_42490	COG0431	NADPH-dependent FMN reductase
RvVAT039_42510	COG0745	RESPONSE REGULATOR receiver
RvVAT039_42520	COG2205	protein histidine kinase activity
RvVAT039_42530	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RvVAT039_42550	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RvVAT039_42590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_42600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RvVAT039_42610	COG1522	sequence-specific DNA binding
RvVAT039_42640	COG2267	carboxylic ester hydrolase activity
RvVAT039_42660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_42670	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_42700	COG1177	transmembrane transport
RvVAT039_42710	COG3842	ATPase activity
RvVAT039_42720	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_42740	COG4154	Belongs to the RbsD FucU family
RvVAT039_42760	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_42770	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_42780	COG1129	ABC transporter
RvVAT039_42820	COG2721	sulfolactate sulfo-lyase activity
RvVAT039_42840	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_42860	COG2205	protein histidine kinase activity
RvVAT039_42870	COG0745	RESPONSE REGULATOR receiver
RvVAT039_42940	COG0183	Belongs to the thiolase family
RvVAT039_42950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RvVAT039_42970	COG1414	Transcriptional regulator
RvVAT039_43000	COG0583	DNA-binding transcription factor activity
RvVAT039_43030	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RvVAT039_43040	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_43050	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_43060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RvVAT039_43070	COG0604	alcohol dehydrogenase
RvVAT039_43080	COG1674	ftsk spoiiie
RvVAT039_43090	COG3842	ATPase activity
RvVAT039_43120	COG0668	transmembrane transport
RvVAT039_43160	COG5265	(ABC) transporter
RvVAT039_43170	COG2205	protein histidine kinase activity
RvVAT039_43180	COG0745	RESPONSE REGULATOR receiver
RvVAT039_43200	COG3346	SURF1 family
RvVAT039_43210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RvVAT039_43220	COG1845	cytochrome c oxidase, subunit III
RvVAT039_43230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RvVAT039_43250	COG1595	DNA-templated transcription, initiation
RvVAT039_43270	COG0670	Belongs to the BI1 family
RvVAT039_43300	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RvVAT039_43300	COG2273	Hydrolase Family 16
RvVAT039_43310	COG1301	dicarboxylic acid transport
RvVAT039_43320	COG4191	Histidine kinase
RvVAT039_43330	COG2204	response regulator
RvVAT039_43340	COG1309	transcriptional regulator
RvVAT039_43380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RvVAT039_43390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RvVAT039_43400	COG2188	Transcriptional regulator
RvVAT039_43430	COG0395	ABC-type sugar transport system, permease component
RvVAT039_43450	COG3842	ATPase activity
RvVAT039_43500	COG1737	Transcriptional regulator
RvVAT039_43500	COG0837	glucose binding
RvVAT039_43510	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_43550	COG3142	Participates in the control of copper homeostasis
RvVAT039_43590	COG0642	Histidine kinase
RvVAT039_43600	COG0745	RESPONSE REGULATOR receiver
RvVAT039_43630	COG4952	isomerase
RvVAT039_43640	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_43640	COG3347	Dehydrogenase
RvVAT039_43670	COG1129	ABC transporter
RvVAT039_43680	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_43700	COG3254	rhamnose metabolic process
RvVAT039_43720	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_43760	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_43780	COG3842	ATPase activity
RvVAT039_43820	COG2094	Belongs to the DNA glycosylase MPG family
RvVAT039_43830	COG1136	(ABC) transporter
RvVAT039_pl00010	COG1737	Transcriptional regulator
RvVAT039_pl00050	COG3177	Filamentation induced by cAMP protein fic
RvVAT039_pl00060	COG1069	ribulokinase activity
RvVAT039_pl00080	COG4214	carbohydrate transport
RvVAT039_pl00140	COG2814	Major facilitator Superfamily
RvVAT039_pl00180	COG1780	Probably involved in ribonucleotide reductase function
RvVAT039_pl00200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RvVAT039_pl00210	COG0640	Transcriptional regulator
RvVAT039_pl00220	COG1902	pentaerythritol trinitrate reductase activity
RvVAT039_pl00230	COG0154	amidase activity
RvVAT039_pl00270	COG0583	DNA-binding transcription factor activity
RvVAT039_pl00290	COG2423	ornithine cyclodeaminase activity
RvVAT039_pl00310	COG0251	oxidation-reduction process
RvVAT039_pl00320	COG1414	Transcriptional regulator
RvVAT039_pl00340	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_pl00380	COG1414	Transcriptional regulator
RvVAT039_pl00420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RvVAT039_pl00440	COG2271	Major facilitator Superfamily
RvVAT039_pl00450	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_pl00480	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_pl00500	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_pl00510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RvVAT039_pl00550	COG0179	Fumarylacetoacetate (FAA) hydrolase
RvVAT039_pl00670	COG3485	protocatechuate 3,4-dioxygenase
RvVAT039_pl00720	COG1177	transmembrane transport
RvVAT039_pl00730	COG3842	ATPase activity
RvVAT039_pl00740	COG1940	carbohydrate kinase activity
RvVAT039_pl00760	COG0673	inositol 2-dehydrogenase activity
RvVAT039_pl00810	COG1573	uracil-dna glycosylase
RvVAT039_pl00840	COG1609	Transcriptional regulator
RvVAT039_pl00870	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_pl00880	COG1735	metal-dependent hydrolase with the TIM-barrel fold
RvVAT039_pl00960	COG0745	RESPONSE REGULATOR receiver
RvVAT039_pl00970	COG2205	protein histidine kinase activity
RvVAT039_pl01010	COG3293	Transposase
RvVAT039_pl01050	COG0697	spore germination
RvVAT039_pl01060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RvVAT039_pl01070	COG2801	Transposase and inactivated derivatives
RvVAT039_pl01110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_pl01130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RvVAT039_pl01140	COG1522	sequence-specific DNA binding
RvVAT039_pl01160	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RvVAT039_pl01180	COG0601	transmembrane transport
RvVAT039_pl01190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl01200	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_pl01210	COG4608	Belongs to the ABC transporter superfamily
RvVAT039_pl01330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RvVAT039_pl01350	COG2986	histidine ammonia-lyase
RvVAT039_pl01380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RvVAT039_pl01420	COG3501	Rhs element vgr protein
RvVAT039_pl01510	COG2826	transposase and inactivated derivatives, IS30 family
RvVAT039_pl01550	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RvVAT039_pl01570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RvVAT039_pl01600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RvVAT039_pl01620	COG2144	transferase activity, transferring acyl groups
RvVAT039_pl01630	COG0438	transferase activity, transferring glycosyl groups
RvVAT039_pl01650	COG2072	flavoprotein involved in K transport
RvVAT039_pl01680	COG0243	molybdopterin cofactor binding
RvVAT039_pl01730	COG0395	ABC-type sugar transport system, permease component
RvVAT039_pl01760	COG1309	transcriptional regulator
RvVAT039_pl01780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_pl01800	COG1177	transmembrane transport
RvVAT039_pl01820	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RvVAT039_pl01870	COG2186	Transcriptional regulator
RvVAT039_pl01890	COG0747	negative chemotaxis
RvVAT039_pl01900	COG0601	transmembrane transport
RvVAT039_pl01910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl01950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RvVAT039_pl01970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_pl01980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
RvVAT039_pl02000	COG1999	signal sequence binding
RvVAT039_pl02040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RvVAT039_pl02050	COG0243	molybdopterin cofactor binding
RvVAT039_pl02060	COG0662	Cupin 2, conserved barrel domain protein
RvVAT039_pl02060	COG2207	Transcriptional regulator
RvVAT039_pl02160	COG3284	Transcriptional regulator
RvVAT039_pl02170	COG1063	alcohol dehydrogenase
RvVAT039_pl02190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_pl02210	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_pl02220	COG0439	Biotin carboxylase
RvVAT039_pl02230	COG0511	ligase activity, forming carbon-carbon bonds
RvVAT039_pl02250	COG1984	allophanate hydrolase subunit 2
RvVAT039_pl02260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RvVAT039_pl02270	COG0436	Aminotransferase
RvVAT039_pl02290	COG4221	oxidoreductase activity
RvVAT039_pl02300	COG0765	amino acid transport
RvVAT039_pl02310	COG0765	amino acid transport
RvVAT039_pl02330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_pl02360	COG2181	nitrate reductase activity
RvVAT039_pl02360	COG0247	lactate metabolic process
RvVAT039_pl02370	COG0277	FAD linked oxidase domain protein
RvVAT039_pl02430	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_pl02450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RvVAT039_pl02460	COG1024	Enoyl-CoA hydratase
RvVAT039_pl02500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RvVAT039_pl02520	COG2801	Transposase and inactivated derivatives
RvVAT039_pl02540	COG1192	Involved in chromosome partitioning
RvVAT039_pl02550	COG1475	DNA binding
RvVAT039_pl02560	COG0640	Transcriptional regulator
RvVAT039_pl02570	COG2072	flavoprotein involved in K transport
RvVAT039_pl02590	COG3706	GGDEF domain
RvVAT039_pl02850	COG3293	Transposase
RvVAT039_pl02910	COG0583	DNA-binding transcription factor activity
RvVAT039_pl02970	COG0243	molybdopterin cofactor binding
RvVAT039_pl02980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RvVAT039_pl03120	COG0175	sulfate reduction
RvVAT039_pl03180	COG1733	regulation of RNA biosynthetic process
RvVAT039_pl03210	COG0596	Alpha beta hydrolase
RvVAT039_pl03220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RvVAT039_pl03230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RvVAT039_pl03240	COG2610	gluconate transmembrane transporter activity
RvVAT039_pl03290	COG0017	Asparaginyl-tRNA synthetase
RvVAT039_pl03320	COG3848	Pyruvate phosphate dikinase
RvVAT039_pl03320	COG0574	Belongs to the PEP-utilizing enzyme family
RvVAT039_pl03330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RvVAT039_pl03340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RvVAT039_pl03400	COG0583	DNA-binding transcription factor activity
RvVAT039_pl03410	COG2814	Major facilitator Superfamily
RvVAT039_pl03430	COG1335	isochorismatase
RvVAT039_pl03440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl03450	COG0154	amidase activity
RvVAT039_pl03460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_pl03490	COG3833	ABC-type maltose transport systems, permease component
RvVAT039_pl03500	COG3842	ATPase activity
RvVAT039_pl03540	COG3609	addiction module antidote protein, CC2985 family
RvVAT039_pl03580	COG4957	zinc ion binding
RvVAT039_pl03630	COG2226	methyltransferase
RvVAT039_pl03770	COG4521	taurine ABC transporter
RvVAT039_pl03780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
RvVAT039_pl03790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_pl03800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl03850	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_pl03860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl03870	COG0601	transmembrane transport
RvVAT039_pl03900	COG1960	acyl-CoA dehydrogenase activity
RvVAT039_pl03920	COG0747	negative chemotaxis
RvVAT039_pl03950	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_pl03970	COG0667	Aldo Keto reductase
RvVAT039_pl03990	COG0778	Nitroreductase
RvVAT039_pl04000	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_pl04010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl04030	COG0747	negative chemotaxis
RvVAT039_pl04050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_pl04060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_pl04070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RvVAT039_pl04090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl04130	COG0747	negative chemotaxis
RvVAT039_pl04140	COG0747	negative chemotaxis
RvVAT039_pl04150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl04180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl04190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl04210	COG0747	negative chemotaxis
RvVAT039_pl04230	COG0747	negative chemotaxis
RvVAT039_pl04240	COG1473	amidohydrolase
RvVAT039_pl04250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl04270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RvVAT039_pl04290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RvVAT039_pl04300	COG0765	amino acid transport
RvVAT039_pl04310	COG1126	abc transporter atp-binding protein
RvVAT039_pl04320	COG1464	Belongs to the NlpA lipoprotein family
RvVAT039_pl04340	COG2011	ABC-type metal ion transport system permease component
RvVAT039_pl04360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RvVAT039_pl04480	COG3938	Belongs to the proline racemase family
RvVAT039_pl04490	COG4176	ABC-type proline glycine betaine transport system permease component
RvVAT039_pl04500	COG4176	ABC-type proline glycine betaine transport system permease component
RvVAT039_pl04510	COG3448	diguanylate cyclase activity
RvVAT039_pl04510	COG4175	Glycine betaine
RvVAT039_pl04530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_pl04540	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_pl04550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RvVAT039_pl04560	COG2186	Transcriptional regulator
RvVAT039_pl04570	COG1802	Transcriptional regulator
RvVAT039_pl04600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_pl04610	COG1349	DNA-binding transcription factor activity
RvVAT039_pl04630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl04640	COG0601	transmembrane transport
RvVAT039_pl04800	COG1120	ATPase activity
RvVAT039_pl04810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_pl04820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RvVAT039_pl04830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RvVAT039_pl04840	COG4774	siderophore transport
RvVAT039_pl04840	COG1629	transport
RvVAT039_pl04940	COG2226	methyltransferase
RvVAT039_pl04960	COG0318	PFAM AMP-dependent synthetase and ligase
RvVAT039_pl05000	COG0534	Mate efflux family protein
RvVAT039_pl05010	COG1959	2 iron, 2 sulfur cluster binding
RvVAT039_pl05070	COG0840	transmembrane signaling receptor activity
RvVAT039_pl05100	COG2362	D-Aminopeptidase
RvVAT039_pl05110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl05140	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_pl05170	COG1940	carbohydrate kinase activity
RvVAT039_pl05190	COG0395	ABC-type sugar transport system, permease component
RvVAT039_pl05200	COG1175	transmembrane transport
RvVAT039_pl05230	COG0110	maltose O-acetyltransferase activity
RvVAT039_pl05290	COG0395	ABC-type sugar transport system, permease component
RvVAT039_pl05300	COG1175	transmembrane transport
RvVAT039_pl05330	COG2186	Transcriptional regulator
RvVAT039_pl05360	COG3842	ATPase activity
RvVAT039_pl05380	COG1175	transmembrane transport
RvVAT039_pl05390	COG0395	ABC-type sugar transport system, permease component
RvVAT039_pl05410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_pl05460	COG2801	Transposase and inactivated derivatives
RvVAT039_pl05460	COG3415	Transposase
RvVAT039_pl05500	COG0840	transmembrane signaling receptor activity
RvVAT039_pl05610	COG0840	transmembrane signaling receptor activity
RvVAT039_pl05800	COG0784	Response regulator, receiver
RvVAT039_pl05800	COG4191	Histidine kinase
RvVAT039_pl05910	COG0784	Response regulator, receiver
RvVAT039_pl05910	COG2205	protein histidine kinase activity
RvVAT039_pl05910	COG2198	Histidine kinase
RvVAT039_pl05930	COG0643	Histidine kinase
RvVAT039_pl05930	COG0784	Response regulator, receiver
RvVAT039_pl05930	COG2198	Histidine kinase
RvVAT039_pl05940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RvVAT039_pl05950	COG2201	protein-glutamate methylesterase activity
RvVAT039_pl05960	COG0835	chemotaxis
RvVAT039_pl06070	COG0583	DNA-binding transcription factor activity
RvVAT039_pl06140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RvVAT039_pl06160	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_pl06180	COG2272	Belongs to the type-B carboxylesterase lipase family
RvVAT039_pl06250	COG0655	NAD(P)H dehydrogenase (quinone) activity
RvVAT039_pl06320	COG0006	proline dipeptidase activity
RvVAT039_pl06340	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_pl06380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_pl06400	COG2188	Transcriptional regulator
RvVAT039_pl06440	COG0187	DNA topoisomerase II activity
RvVAT039_pl06450	COG0187	DNA topoisomerase II activity
RvVAT039_pl06470	COG2801	Transposase and inactivated derivatives
RvVAT039_pl06470	COG3415	Transposase
RvVAT039_pl06490	COG1178	ABC-type Fe3 transport system permease component
RvVAT039_pl06500	COG0436	Aminotransferase
RvVAT039_pl06520	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
RvVAT039_pl06530	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
RvVAT039_pl06550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RvVAT039_pl06560	COG2222	sugar isomerase
RvVAT039_pl06570	COG2188	Transcriptional regulator
RvVAT039_pl06590	COG0601	transmembrane transport
RvVAT039_pl06630	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_pl06640	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_pl06650	COG3335	DDE superfamily endonuclease
RvVAT039_pl06660	COG3415	Transposase
RvVAT039_pl06730	COG1473	amidohydrolase
RvVAT039_pl06770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RvVAT039_pl06780	COG1301	dicarboxylic acid transport
RvVAT039_pl06790	COG0583	DNA-binding transcription factor activity
RvVAT039_pl06800	COG2159	amidohydrolase
RvVAT039_pl06850	COG3181	Tripartite tricarboxylate transporter family receptor
RvVAT039_pl06860	COG2814	Major facilitator Superfamily
RvVAT039_pl06920	COG1609	Transcriptional regulator
RvVAT039_pl07000	COG0601	transmembrane transport
RvVAT039_pl07040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RvVAT039_pl07050	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_pl07060	COG3842	ATPase activity
RvVAT039_pl07080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_pl07090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RvVAT039_pl07100	COG3284	Transcriptional regulator
RvVAT039_pl07110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RvVAT039_pl07130	COG1012	belongs to the aldehyde dehydrogenase family
RvVAT039_pl07160	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_pl07180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RvVAT039_pl07300	COG1074	ATP-dependent DNA helicase activity
RvVAT039_pl07310	COG1074	ATP-dependent DNA helicase activity
RvVAT039_pl07420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RvVAT039_pl07480	COG3701	Conjugal transfer protein
RvVAT039_pl07490	COG3846	protein secretion by the type IV secretion system
RvVAT039_pl07510	COG5314	conjugation
RvVAT039_pl07520	COG3451	type IV secretory pathway VirB4
RvVAT039_pl07550	COG4962	Type ii secretion system protein e
RvVAT039_pl07570	COG1192	Involved in chromosome partitioning
RvVAT039_pl07580	COG1475	DNA binding
RvVAT039_pl07590	COG0640	Transcriptional regulator
RvVAT039_pl07690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RvVAT039_pl07750	COG2801	Transposase and inactivated derivatives
RvVAT039_pl07870	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_pl07880	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_pl07910	COG1473	amidohydrolase
RvVAT039_pl07950	COG1802	Transcriptional regulator
RvVAT039_pl07960	COG3938	Belongs to the proline racemase family
RvVAT039_pl07990	COG3938	Belongs to the proline racemase family
RvVAT039_pl08040	COG0747	negative chemotaxis
RvVAT039_pl08050	COG0601	transmembrane transport
RvVAT039_pl08060	COG0444	Belongs to the ABC transporter superfamily
RvVAT039_pl08100	COG0583	DNA-binding transcription factor activity
RvVAT039_pl08110	COG2814	Major facilitator Superfamily
RvVAT039_pl08220	COG1475	DNA binding
RvVAT039_pl08270	COG0300	oxidoreductase activity
RvVAT039_pl08300	COG5489	Protein of unknown function (DUF736)
RvVAT039_pl08310	COG0776	regulation of translation
RvVAT039_pl08320	COG3831	ATPase activity
RvVAT039_pl08390	COG3501	Rhs element vgr protein
RvVAT039_pl08510	COG2207	Transcriptional regulator
RvVAT039_pl08550	COG4598	ABC transporter
RvVAT039_pl08580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RvVAT039_pl08600	COG2826	transposase and inactivated derivatives, IS30 family
RvVAT039_pl08720	COG1609	Transcriptional regulator
RvVAT039_pl08730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RvVAT039_pl08770	COG1172	Belongs to the binding-protein-dependent transport system permease family
RvVAT039_pl08780	COG1129	ABC transporter
RvVAT039_pl08790	COG1028	Short-chain dehydrogenase reductase Sdr
RvVAT039_pl08900	COG3293	Transposase
RvVAT039_pl08960	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RvVAT039_pl09010	COG2205	protein histidine kinase activity
RvVAT039_pl09010	COG4999	Histidine kinase
RvVAT039_pl09010	COG3850	Histidine kinase
RvVAT039_pl09010	COG3437	response regulator, receiver
RvVAT039_pl09020	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RvVAT039_pl09040	COG5002	protein histidine kinase activity
RvVAT039_pl09070	COG2972	Histidine kinase
RvVAT039_pl09070	COG0840	transmembrane signaling receptor activity
RvVAT039_pl09110	COG4644	lycopene metabolic process
RvVAT039_pl09140	COG0419	ATPase involved in DNA repair
RvVAT039_pl09250	COG3415	Transposase
RvVAT039_pl09260	COG3335	DDE superfamily endonuclease
RvVAT039_pl09360	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RvVAT039_pl09420	COG0640	Transcriptional regulator
RvVAT039_pl09430	COG1475	DNA binding
RvVAT039_pl09440	COG1192	Involved in chromosome partitioning
RvVAT039_pl09460	COG4962	Type ii secretion system protein e
RvVAT039_pl09490	COG3451	type IV secretory pathway VirB4
RvVAT039_pl09500	COG5314	conjugation
RvVAT039_pl09520	COG3846	protein secretion by the type IV secretion system
RvVAT039_pl09530	COG3701	Conjugal transfer protein
RvVAT039_pl09640	COG4166	transmembrane transport
RvVAT039_pl09650	COG0601	transmembrane transport
RvVAT039_pl09670	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_pl09690	COG1840	ABC-type Fe3 transport system, periplasmic component
RvVAT039_pl09700	COG3842	ATPase activity
RvVAT039_pl09710	COG1177	transmembrane transport
RvVAT039_pl09720	COG4149	molybdate abc transporter
RvVAT039_pl09840	COG3415	Transposase
RvVAT039_pl09850	COG3335	DDE superfamily endonuclease
RvVAT039_pl09900	COG3293	Transposase
RvVAT039_pl09910	COG3293	Transposase
RvVAT039_pl10030	COG3344	reverse transcriptase
RvVAT039_pl10060	COG0582	viral genome integration into host DNA
RvVAT039_pl10070	COG3415	Transposase
RvVAT039_pl10080	COG3335	DDE superfamily endonuclease
RvVAT039_pl10100	COG3344	reverse transcriptase
RvVAT039_pl10120	COG0582	viral genome integration into host DNA
RvVAT039_pl10130	COG4974	Belongs to the 'phage' integrase family
RvVAT039_pl10160	COG4372	Transposase
RvVAT039_pl10200	COG3293	Transposase
RvVAT039_pl10290	COG4372	Transposase
RvVAT039_pl10320	COG4372	Transposase
RvVAT039_pl10460	COG0745	RESPONSE REGULATOR receiver
RvVAT039_pl10480	COG1192	Involved in chromosome partitioning
RvVAT039_pl10540	COG3415	Transposase
RvVAT039_pl10560	COG3293	Transposase
RvVAT039_pl10600	COG1192	Involved in chromosome partitioning
RvVAT039_pl10680	COG1064	alcohol dehydrogenase
RvVAT039_pl10700	COG4172	Belongs to the ABC transporter superfamily
RvVAT039_pl10720	COG0601	transmembrane transport
RvVAT039_pl10770	COG1840	ABC-type Fe3 transport system, periplasmic component
RvVAT039_pl10790	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_pl10830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RvVAT039_pl10850	COG0747	negative chemotaxis
RvVAT039_pl10870	COG3842	ATPase activity
RvVAT039_pl10880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RvVAT039_pl10890	COG1177	transmembrane transport
RvVAT039_pl10900	COG1176	ABC-type spermidine putrescine transport system, permease component I
RvVAT039_pl10920	COG1177	transmembrane transport
RvVAT039_pl10930	COG1177	transmembrane transport
RvVAT039_pl10940	COG3842	ATPase activity
RvVAT039_pl10970	COG1522	sequence-specific DNA binding
RvVAT039_pl10980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RvVAT039_pl11130	COG3831	ATPase activity
RvVAT039_pl11140	COG0776	regulation of translation
RvVAT039_pl11150	COG5489	Protein of unknown function (DUF736)
RvVAT039_pl11160	COG5489	Protein of unknown function (DUF736)
RvVAT039_pl11190	COG0582	viral genome integration into host DNA
RvVAT039_pl11200	COG0582	viral genome integration into host DNA
RvVAT039_pl11210	COG4974	Belongs to the 'phage' integrase family
RvVAT039_pl11250	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_pl11260	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_pl11270	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_pl11280	COG3415	Transposase
RvVAT039_pl11290	COG3335	DDE superfamily endonuclease
RvVAT039_pl11300	COG3547	Transposase (IS116 IS110 IS902 family)
RvVAT039_pl11370	COG1475	DNA binding
RvVAT039_pl11380	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RvVAT039_pl11420	COG3335	DDE superfamily endonuclease
RvVAT039_pl11430	COG3415	Transposase
RvVAT039_pl11440	COG2890	protein-(glutamine-N5) methyltransferase activity
RvVAT039_pl11540	COG3300	MHYT domain
RvVAT039_pl11540	COG5001	Diguanylate cyclase
RvVAT039_pl11550	COG1396	sequence-specific DNA binding
RvVAT039_pl11620	COG3415	Transposase
RvVAT039_pl11620	COG2801	Transposase and inactivated derivatives
RvVAT039_pl11780	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
RvVAT039_pl11880	COG0515	serine threonine protein kinase
RvVAT039_pl11890	COG0515	serine threonine protein kinase
RvVAT039_pl11890	COG2815	serine threonine protein kinase
RvVAT039_pl11980	COG3706	GGDEF domain
RvVAT039_pl12000	COG0640	Transcriptional regulator
RvVAT039_pl12010	COG1475	DNA binding
RvVAT039_pl12020	COG1192	Involved in chromosome partitioning
RvVAT039_pl12030	COG4227	nucleotidyltransferase activity
RvVAT039_pl12040	COG2184	nucleotidyltransferase activity
RvVAT039_pl12100	COG1475	DNA binding
RvVAT039_pl12280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RvVAT039_pl12340	COG0789	Transcriptional regulator
RvVAT039_pl12540	COG0789	Transcriptional regulator
RvVAT039_pl12550	COG1914	H( )-stimulated, divalent metal cation uptake system
RvVAT039_pl12640	COG0741	lytic transglycosylase activity
RvVAT039_pl12650	COG3838	Conjugal transfer protein Trbc
RvVAT039_pl12670	COG3451	type IV secretory pathway VirB4
RvVAT039_pl12680	COG0741	lytic transglycosylase activity
RvVAT039_pl12800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RvVAT039_pl12850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RvVAT039_pl12870	COG3621	Patatin-like phospholipase
RvVAT039_pl12940	COG1505	serine-type exopeptidase activity
RvVAT039_pl12980	COG1280	lysine exporter protein (LysE YggA)
RvVAT039_pl13080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RvVAT039_pl13100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RvVAT039_pl13160	COG4644	lycopene metabolic process
RvVAT039_pl13170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs