locus-tag	class	description
JSQ78_00005	COG0613	PHP domain protein
JSQ78_00010	COG0513	Belongs to the DEAD box helicase family
JSQ78_00065	COG3480	Lon protease (S16) C-terminal proteolytic domain
JSQ78_00070	COG1615	UPF0182 protein
JSQ78_00100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JSQ78_00110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JSQ78_00140	COG1174	glycine betaine transport
JSQ78_00145	COG1174	glycine betaine transport
JSQ78_00170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JSQ78_00175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JSQ78_00180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JSQ78_00185	COG0803	Belongs to the bacterial solute-binding protein 9 family
JSQ78_00190	COG1121	(ABC) transporter
JSQ78_00195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JSQ78_00200	COG1321	iron dependent repressor
JSQ78_00215	COG0300	oxidoreductase activity
JSQ78_00220	COG1250	3-hydroxyacyl-CoA dehydrogenase
JSQ78_00240	COG0596	Alpha beta hydrolase
JSQ78_00585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JSQ78_00595	COG2884	Cell division ATP-binding protein ftsE
JSQ78_00600	COG2177	Part of the ABC transporter FtsEX involved in
JSQ78_00605	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JSQ78_00620	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_00645	COG0483	inositol monophosphate 1-phosphatase activity
JSQ78_00650	COG1162	GTPase activity
JSQ78_00670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JSQ78_00700	COG0438	transferase activity, transferring glycosyl groups
JSQ78_00750	COG0489	protein tyrosine kinase activity
JSQ78_00760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JSQ78_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ78_00765	COG0567	Dehydrogenase, E1 component
JSQ78_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ78_00765	COG0567	Dehydrogenase, E1 component
JSQ78_00785	COG1253	flavin adenine dinucleotide binding
JSQ78_00795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JSQ78_00810	COG2814	Major facilitator Superfamily
JSQ78_00825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JSQ78_00830	COG0571	ribonuclease III activity
JSQ78_00835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JSQ78_00845	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_00885	COG2813	Specifically methylates the guanine in position
JSQ78_00890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JSQ78_00915	COG4607	ABC-type enterochelin transport system periplasmic component
JSQ78_00945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_00950	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JSQ78_00955	COG0228	four-way junction DNA binding
JSQ78_00960	COG1837	Belongs to the UPF0109 family
JSQ78_00965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JSQ78_00970	COG0336	Belongs to the RNA methyltransferase TrmD family
JSQ78_00980	COG0335	large ribosomal subunit rRNA binding
JSQ78_00990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JSQ78_01000	COG0792	nuclease activity
JSQ78_01020	COG4974	Belongs to the 'phage' integrase family
JSQ78_01030	COG0052	Belongs to the universal ribosomal protein uS2 family
JSQ78_01035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JSQ78_01040	COG0528	UMP kinase activity
JSQ78_01045	COG0233	cytoplasmic translational termination
JSQ78_01080	COG3118	belongs to the thioredoxin family
JSQ78_01085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JSQ78_01110	COG1216	Glycosyl transferase, family 2
JSQ78_01115	COG0482	sulfurtransferase activity
JSQ78_01135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JSQ78_01160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JSQ78_01165	COG0154	amidase activity
JSQ78_01170	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JSQ78_01185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_01200	COG4721	ABC-type cobalt transport system, permease component
JSQ78_01205	COG4172	Belongs to the ABC transporter superfamily
JSQ78_01245	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JSQ78_01265	COG0586	Pfam SNARE associated Golgi protein
JSQ78_01280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JSQ78_01305	COG0824	Thioesterase
JSQ78_01315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JSQ78_01320	COG1946	Acyl-CoA thioesterase
JSQ78_01345	COG2135	peptidase activity
JSQ78_01350	COG1309	transcriptional regulator
JSQ78_01365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JSQ78_01365	COG0512	Glutamine amidotransferase of anthranilate synthase
JSQ78_01370	COG0640	Transcriptional regulator
JSQ78_01385	COG0495	leucyl-tRNA aminoacylation
JSQ78_01405	COG1396	sequence-specific DNA binding
JSQ78_01425	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JSQ78_01430	COG0268	Binds directly to 16S ribosomal RNA
JSQ78_01435	COG0481	GTPase activity
JSQ78_01455	COG1420	regulation of RNA biosynthetic process
JSQ78_01460	COG0484	heat shock protein binding
JSQ78_01465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JSQ78_01470	COG0537	adenosine 5'-monophosphoramidase activity
JSQ78_01480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JSQ78_01495	COG4585	Histidine kinase
JSQ78_01500	COG2197	response regulator
JSQ78_01505	COG1073	alpha beta
JSQ78_01505	COG2226	methyltransferase
JSQ78_01510	COG0577	efflux transmembrane transporter activity
JSQ78_01510	COG1136	(ABC) transporter
JSQ78_01515	COG0577	efflux transmembrane transporter activity
JSQ78_01520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JSQ78_01525	COG1381	Involved in DNA repair and RecF pathway recombination
JSQ78_01530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JSQ78_01555	COG0423	glycine-tRNA ligase activity
JSQ78_01570	COG0358	DNA primase activity
JSQ78_01580	COG1690	Belongs to the RtcB family
JSQ78_01595	COG0242	peptide deformylase activity
JSQ78_01605	COG0438	transferase activity, transferring glycosyl groups
JSQ78_01630	COG0671	phosphoesterase, PA-phosphatase related
JSQ78_01670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JSQ78_01675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JSQ78_01690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JSQ78_01715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JSQ78_01760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JSQ78_01765	COG0174	glutamine synthetase
JSQ78_01770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JSQ78_01780	COG0174	glutamine synthetase
JSQ78_01795	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ78_01800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JSQ78_01805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JSQ78_01820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JSQ78_01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JSQ78_01830	COG0765	amino acid transport
JSQ78_01835	COG1126	abc transporter atp-binding protein
JSQ78_01845	COG0187	DNA topoisomerase II activity
JSQ78_01850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JSQ78_01890	COG0756	dUTP diphosphatase activity
JSQ78_01905	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JSQ78_01910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JSQ78_01925	COG2890	protein-(glutamine-N5) methyltransferase activity
JSQ78_01930	COG1024	Enoyl-CoA hydratase
JSQ78_01930	COG1250	3-hydroxyacyl-CoA dehydrogenase
JSQ78_01935	COG0183	Belongs to the thiolase family
JSQ78_01950	COG1073	alpha beta
JSQ78_01950	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
JSQ78_01950	COG3064	Membrane
JSQ78_01970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JSQ78_02035	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JSQ78_02045	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JSQ78_02050	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JSQ78_02065	COG0217	transcriptional regulatory protein
JSQ78_02070	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JSQ78_02085	COG2255	four-way junction helicase activity
JSQ78_02095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JSQ78_02100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JSQ78_02105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JSQ78_02120	COG1196	nuclear chromosome segregation
JSQ78_02135	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JSQ78_02145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JSQ78_02150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JSQ78_02155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JSQ78_02160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JSQ78_02165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JSQ78_02170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JSQ78_02175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JSQ78_02180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JSQ78_02185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JSQ78_02190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JSQ78_02200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JSQ78_02205	COG0540	Belongs to the ATCase OTCase family
JSQ78_02210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JSQ78_02220	COG0505	Belongs to the CarA family
JSQ78_02225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JSQ78_02230	COG0284	orotidine-5'-phosphate decarboxylase activity
JSQ78_02235	COG0194	GDP metabolic process
JSQ78_02240	COG1758	RNA polymerase activity
JSQ78_02250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JSQ78_02255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JSQ78_02260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JSQ78_02270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JSQ78_02275	COG0140	phosphoribosyl-ATP diphosphatase activity
JSQ78_02280	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JSQ78_02285	COG0107	imidazoleglycerol-phosphate synthase activity
JSQ78_02310	COG0134	indole-3-glycerol-phosphate synthase activity
JSQ78_02315	COG0133	tryptophan synthase activity
JSQ78_02320	COG0159	tryptophan synthase activity
JSQ78_02325	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JSQ78_02330	COG0067	glutamate synthase
JSQ78_02330	COG0069	glutamate synthase activity
JSQ78_02330	COG0070	glutamate synthase
JSQ78_02340	COG0469	pyruvate kinase activity
JSQ78_02360	COG2050	protein possibly involved in aromatic compounds catabolism
JSQ78_02370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_02380	COG0539	negative regulation of cytoplasmic translation
JSQ78_02385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JSQ78_02395	COG5002	protein histidine kinase activity
JSQ78_02405	COG0745	RESPONSE REGULATOR receiver
JSQ78_02410	COG0237	dephospho-CoA kinase activity
JSQ78_02415	COG0556	nucleotide-excision repair
JSQ78_02425	COG4770	biotin carboxylase activity
JSQ78_02435	COG0322	excinuclease ABC activity
JSQ78_02440	COG1660	Displays ATPase and GTPase activities
JSQ78_02445	COG1481	regulation of sporulation
JSQ78_02450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JSQ78_02460	COG0126	phosphoglycerate kinase activity
JSQ78_02465	COG0149	triose-phosphate isomerase activity
JSQ78_02470	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JSQ78_02480	COG0363	glucosamine-6-phosphate deaminase activity
JSQ78_02500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JSQ78_02510	COG0109	protoheme IX farnesyltransferase activity
JSQ78_02515	COG0248	Ppx GppA phosphatase
JSQ78_02520	COG1612	heme a metabolic process
JSQ78_02540	COG0396	ATPase activity
JSQ78_02545	COG2151	metal-sulfur cluster biosynthetic enzyme
JSQ78_02565	COG1268	BioY protein
JSQ78_02575	COG0488	(ABC) transporter
JSQ78_02580	COG2860	membrane
JSQ78_02600	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_02610	COG0560	Phosphoserine phosphatase
JSQ78_02615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JSQ78_02620	COG0297	glycogen (starch) synthase activity
JSQ78_02625	COG1119	ATPase activity
JSQ78_02630	COG0254	rRNA binding
JSQ78_02640	COG2176	DNA-directed DNA polymerase activity
JSQ78_02640	COG5002	protein histidine kinase activity
JSQ78_02650	COG0438	transferase activity, transferring glycosyl groups
JSQ78_02675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JSQ78_02690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JSQ78_02695	COG1968	undecaprenyl-diphosphatase activity
JSQ78_02700	COG0215	cysteine-tRNA ligase activity
JSQ78_02710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JSQ78_02740	COG0805	protein transport
JSQ78_02755	COG1216	Glycosyl transferase, family 2
JSQ78_02775	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_02780	COG4946	Tricorn protease homolog
JSQ78_02780	COG1506	peptidase
JSQ78_02780	COG0823	Involved in the tonB-independent uptake of proteins
JSQ78_02795	COG1597	lipid kinase activity
JSQ78_02795	COG1803	Methylglyoxal synthase
JSQ78_02805	COG0626	cystathionine gamma-synthase activity
JSQ78_02835	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
JSQ78_02875	COG0622	Phosphoesterase
JSQ78_02930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JSQ78_02930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JSQ78_02970	COG1461	Dihydroxyacetone kinase
JSQ78_02975	COG2376	Dihydroxyacetone kinase
JSQ78_02980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JSQ78_02985	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JSQ78_02995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JSQ78_03000	COG1845	cytochrome c oxidase, subunit III
JSQ78_03005	COG2010	Cytochrome c
JSQ78_03010	COG0723	plastoquinol--plastocyanin reductase activity
JSQ78_03015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JSQ78_03065	COG0697	spore germination
JSQ78_03080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JSQ78_03090	COG2873	o-acetylhomoserine
JSQ78_03095	COG0747	negative chemotaxis
JSQ78_03100	COG0601	transmembrane transport
JSQ78_03105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JSQ78_03115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_03140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JSQ78_03145	COG1695	Transcriptional regulator
JSQ78_03150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JSQ78_03170	COG2226	methyltransferase
JSQ78_03205	COG1846	Transcriptional regulator
JSQ78_03225	COG2267	carboxylic ester hydrolase activity
JSQ78_03230	COG3842	ATPase activity
JSQ78_03240	COG0395	ABC-type sugar transport system, permease component
JSQ78_03245	COG1175	transmembrane transport
JSQ78_03265	COG0464	growth
JSQ78_03290	COG4691	Plasmid stability protein
JSQ78_03315	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JSQ78_03320	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ78_03325	COG0022	dehydrogenase e1 component
JSQ78_03345	COG2514	catechol 2,3-dioxygenase activity
JSQ78_03365	COG2957	Belongs to the agmatine deiminase family
JSQ78_03370	COG0154	amidase activity
JSQ78_03375	COG0799	negative regulation of ribosome biogenesis
JSQ78_03385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JSQ78_03395	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JSQ78_03400	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JSQ78_03405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JSQ78_03410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JSQ78_03415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JSQ78_03425	COG1530	ribonuclease E activity
JSQ78_03440	COG0105	UTP biosynthetic process
JSQ78_03450	COG0285	dihydrofolate synthase activity
JSQ78_03455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JSQ78_03465	COG2197	response regulator
JSQ78_03495	COG0477	Major facilitator Superfamily
JSQ78_03505	COG0326	Molecular chaperone. Has ATPase activity
JSQ78_03510	COG1739	Uncharacterized protein family UPF0029
JSQ78_03530	COG0525	valine-tRNA ligase activity
JSQ78_03545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JSQ78_03565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JSQ78_03570	COG1120	ATPase activity
JSQ78_03575	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JSQ78_03585	COG0740	serine-type endopeptidase activity
JSQ78_03590	COG0740	serine-type endopeptidase activity
JSQ78_03595	COG0544	peptidyl-prolyl cis-trans isomerase activity
JSQ78_03620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JSQ78_03625	COG0384	phenazine biosynthesis protein PhzF
JSQ78_03685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JSQ78_03700	COG2346	COG2346, Truncated hemoglobins
JSQ78_03705	COG3573	Dehydrogenase
JSQ78_03715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JSQ78_03720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JSQ78_03730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JSQ78_03740	COG0167	dihydroorotate dehydrogenase activity
JSQ78_03745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JSQ78_03750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JSQ78_03765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JSQ78_03780	COG1799	cell septum assembly
JSQ78_03785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JSQ78_03800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JSQ78_03805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JSQ78_03815	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JSQ78_03820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JSQ78_03830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JSQ78_03835	COG0768	penicillin binding
JSQ78_03845	COG0275	rRNA processing
JSQ78_03850	COG2001	Belongs to the MraZ family
JSQ78_03860	COG0142	geranyltranstransferase activity
JSQ78_03870	COG2815	serine threonine protein kinase
JSQ78_03870	COG0515	serine threonine protein kinase
JSQ78_03875	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
JSQ78_03880	COG0204	Acyl-transferase
JSQ78_03885	COG1022	Amp-dependent synthetase and ligase
JSQ78_03895	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JSQ78_03900	COG1192	Involved in chromosome partitioning
JSQ78_03930	COG0519	Catalyzes the synthesis of GMP from XMP
JSQ78_03935	COG0519	Catalyzes the synthesis of GMP from XMP
JSQ78_03935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JSQ78_03940	COG1929	Belongs to the glycerate kinase type-1 family
JSQ78_03945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_03950	COG0183	Belongs to the thiolase family
JSQ78_03960	COG0446	pyridine nucleotide-disulphide oxidoreductase
JSQ78_03960	COG1902	pentaerythritol trinitrate reductase activity
JSQ78_03965	COG0626	cystathionine gamma-synthase activity
JSQ78_04000	COG2409	Drug exporters of the RND superfamily
JSQ78_04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JSQ78_04045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JSQ78_04050	COG2963	transposase activity
JSQ78_04085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JSQ78_04095	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
JSQ78_04150	COG2375	cellular response to nickel ion
JSQ78_04155	COG2814	Major facilitator Superfamily
JSQ78_04160	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JSQ78_04165	COG1160	GTP binding
JSQ78_04170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JSQ78_04185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JSQ78_04190	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JSQ78_04210	COG0494	nUDIX hydrolase
JSQ78_04215	COG0504	CTP synthase activity
JSQ78_04220	COG0497	DNA recombination
JSQ78_04225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JSQ78_04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JSQ78_04250	COG1011	Hydrolase
JSQ78_04280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JSQ78_04285	COG0165	Argininosuccinate lyase
JSQ78_04290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JSQ78_04295	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JSQ78_04300	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JSQ78_04305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JSQ78_04315	COG0072	phenylalanine-tRNA ligase activity
JSQ78_04315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JSQ78_04320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JSQ78_04325	COG0765	amino acid transport
JSQ78_04330	COG0765	amino acid transport
JSQ78_04335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JSQ78_04340	COG1126	abc transporter atp-binding protein
JSQ78_04345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JSQ78_04350	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JSQ78_04355	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JSQ78_04360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JSQ78_04375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JSQ78_04380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JSQ78_04385	COG0131	Imidazoleglycerol-phosphate dehydratase
JSQ78_04390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JSQ78_04400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JSQ78_04405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JSQ78_04410	COG2813	Specifically methylates the guanine in position
JSQ78_04415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JSQ78_04420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JSQ78_04425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JSQ78_04435	COG2137	regulation of response to DNA damage stimulus
JSQ78_04440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JSQ78_04450	COG1396	sequence-specific DNA binding
JSQ78_04455	COG1546	Belongs to the CinA family
JSQ78_04455	COG1058	Belongs to the CinA family
JSQ78_04465	COG1674	ftsk spoiiie
JSQ78_04470	COG0577	efflux transmembrane transporter activity
JSQ78_04470	COG1136	(ABC) transporter
JSQ78_04475	COG1136	(ABC) transporter
JSQ78_04475	COG0577	efflux transmembrane transporter activity
JSQ78_04500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JSQ78_04505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JSQ78_04515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JSQ78_04525	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JSQ78_04535	COG0588	phosphoglycerate mutase activity
JSQ78_04540	COG0612	Peptidase, M16
JSQ78_04545	COG1185	polyribonucleotide nucleotidyltransferase activity
JSQ78_04550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JSQ78_04580	COG3483	tryptophan 2,3-dioxygenase activity
JSQ78_04585	COG2890	protein-(glutamine-N5) methyltransferase activity
JSQ78_04610	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_04615	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_04620	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JSQ78_04625	COG0196	riboflavin kinase activity
JSQ78_04640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JSQ78_04645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JSQ78_04665	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JSQ78_04670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JSQ78_04675	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JSQ78_04685	COG0195	Participates in both transcription termination and antitermination
JSQ78_04690	COG1115	amino acid carrier protein
JSQ78_04695	COG0442	prolyl-tRNA aminoacylation
JSQ78_04725	COG0714	Associated with various cellular activities
JSQ78_04730	COG0477	Major facilitator Superfamily
JSQ78_04735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JSQ78_04740	COG0328	RNA-DNA hybrid ribonuclease activity
JSQ78_04745	COG0750	zinc metalloprotease
JSQ78_04760	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JSQ78_04775	COG0686	Belongs to the AlaDH PNT family
JSQ78_04795	COG0714	Associated with various cellular activities
JSQ78_04805	COG0515	serine threonine protein kinase
JSQ78_04805	COG2815	serine threonine protein kinase
JSQ78_04810	COG0631	protein serine/threonine phosphatase activity
JSQ78_04825	COG2217	Heavy metal translocating P-type atpase
JSQ78_04835	COG0667	Aldo Keto reductase
JSQ78_04845	COG0514	ATP-dependent DNA helicase (RecQ)
JSQ78_04865	COG3022	response to hydroperoxide
JSQ78_04870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JSQ78_04875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JSQ78_04880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JSQ78_04885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JSQ78_04890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JSQ78_04895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JSQ78_04900	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JSQ78_04905	COG0356	it plays a direct role in the translocation of protons across the membrane
JSQ78_04935	COG1045	serine acetyltransferase
JSQ78_04940	COG2076	Multidrug Resistance protein
JSQ78_04970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JSQ78_04980	COG0083	homoserine kinase activity
JSQ78_04985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JSQ78_04990	COG0460	homoserine dehydrogenase
JSQ78_05000	COG2094	Belongs to the DNA glycosylase MPG family
JSQ78_05005	COG0018	arginyl-trna synthetase
JSQ78_05035	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JSQ78_05055	COG4968	Prepilin-type N-terminal cleavage methylation domain
JSQ78_05060	COG1459	type II secretion system
JSQ78_05070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JSQ78_05090	COG1937	Protein conserved in bacteria
JSQ78_05115	COG2205	protein histidine kinase activity
JSQ78_05115	COG0745	RESPONSE REGULATOR receiver
JSQ78_05115	COG3292	Two component regulator propeller
JSQ78_05130	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
JSQ78_05160	COG1842	Phage shock protein A
JSQ78_05165	COG0297	glycogen (starch) synthase activity
JSQ78_05175	COG0154	amidase activity
JSQ78_05190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JSQ78_05200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JSQ78_05215	COG4139	cobalamin transport
JSQ78_05220	COG1120	ATPase activity
JSQ78_05225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JSQ78_05230	COG1920	GTP binding
JSQ78_05245	COG0714	Associated with various cellular activities
JSQ78_05250	COG0778	Nitroreductase
JSQ78_05250	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
JSQ78_05255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JSQ78_05265	COG0742	ribosomal rna small subunit methyltransferase
JSQ78_05295	COG0517	IMP dehydrogenase activity
JSQ78_05295	COG4175	Glycine betaine
JSQ78_05300	COG4176	ABC-type proline glycine betaine transport system permease component
JSQ78_05345	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_05355	COG0318	PFAM AMP-dependent synthetase and ligase
JSQ78_05395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JSQ78_05400	COG1570	exodeoxyribonuclease VII activity
JSQ78_05405	COG0477	Major facilitator Superfamily
JSQ78_05410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JSQ78_05415	COG1722	exodeoxyribonuclease VII activity
JSQ78_05425	COG0114	fumarate hydratase activity
JSQ78_05440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JSQ78_05445	COG0477	Major facilitator Superfamily
JSQ78_05450	COG1522	sequence-specific DNA binding
JSQ78_05455	COG1505	serine-type exopeptidase activity
JSQ78_05465	COG2011	ABC-type metal ion transport system permease component
JSQ78_05470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JSQ78_05510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JSQ78_05530	COG0653	protein targeting
JSQ78_05535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JSQ78_05545	COG5401	PFAM Sporulation and spore germination
JSQ78_05550	COG5002	protein histidine kinase activity
JSQ78_05560	COG1966	Carbon starvation protein
JSQ78_05575	COG0488	(ABC) transporter
JSQ78_05580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JSQ78_05590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JSQ78_05600	COG0084	hydrolase, TatD family'
JSQ78_05615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JSQ78_05630	COG1331	Highly conserved protein containing a thioredoxin domain
JSQ78_05670	COG1960	acyl-CoA dehydrogenase activity
JSQ78_05685	COG1902	pentaerythritol trinitrate reductase activity
JSQ78_05690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JSQ78_05695	COG2079	MmgE PrpD family protein
JSQ78_05725	COG1061	Type III restriction enzyme res subunit
JSQ78_05740	COG0662	Cupin 2, conserved barrel domain protein
JSQ78_05750	COG1643	Atp-dependent helicase
JSQ78_05825	COG3281	Trehalose synthase
JSQ78_05835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JSQ78_05845	COG3281	Trehalose synthase
JSQ78_05850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JSQ78_05855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JSQ78_05880	COG0477	Major facilitator Superfamily
JSQ78_05895	COG4988	ABC transporter
JSQ78_05910	COG0501	Belongs to the peptidase M48B family
JSQ78_05920	COG1271	oxidase subunit
JSQ78_05925	COG1294	oxidase, subunit
JSQ78_06000	COG0739	heme binding
JSQ78_06000	COG0741	lytic transglycosylase activity
JSQ78_06000	COG1196	nuclear chromosome segregation
JSQ78_06005	COG1136	(ABC) transporter
JSQ78_06030	COG1937	Protein conserved in bacteria
JSQ78_06035	COG2217	Heavy metal translocating P-type atpase
JSQ78_06085	COG0739	heme binding
JSQ78_06115	COG0785	Cytochrome C biogenesis protein
JSQ78_06120	COG1333	cytochrome c biogenesis protein
JSQ78_06125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JSQ78_06150	COG0791	NLP P60 protein
JSQ78_06160	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JSQ78_06170	COG1278	Cold shock
JSQ78_06185	COG1061	Type III restriction enzyme res subunit
JSQ78_06190	COG0745	RESPONSE REGULATOR receiver
JSQ78_06195	COG2205	protein histidine kinase activity
JSQ78_06205	COG0459	protein refolding
JSQ78_06220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JSQ78_06255	COG3842	ATPase activity
JSQ78_06265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JSQ78_06270	COG0215	cysteine-tRNA ligase activity
JSQ78_06275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JSQ78_06275	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JSQ78_06280	COG1329	Transcriptional regulator
JSQ78_06290	COG0745	RESPONSE REGULATOR receiver
JSQ78_06295	COG5002	protein histidine kinase activity
JSQ78_06300	COG0704	Plays a role in the regulation of phosphate uptake
JSQ78_06305	COG0588	phosphoglycerate mutase activity
JSQ78_06320	COG0354	folic acid binding
JSQ78_06325	COG4044	May play a role in the intracellular transport of hydrophobic ligands
JSQ78_06335	COG0745	RESPONSE REGULATOR receiver
JSQ78_06340	COG0456	acetyltransferase
JSQ78_06345	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JSQ78_06350	COG0406	alpha-ribazole phosphatase activity
JSQ78_06350	COG0494	nUDIX hydrolase
JSQ78_06355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JSQ78_06360	COG0581	inorganic phosphate transmembrane transporter activity
JSQ78_06385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JSQ78_06410	COG2011	ABC-type metal ion transport system permease component
JSQ78_06415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JSQ78_06425	COG2017	converts alpha-aldose to the beta-anomer
JSQ78_06435	COG0395	ABC-type sugar transport system, permease component
JSQ78_06440	COG1175	transmembrane transport
JSQ78_06485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JSQ78_06490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JSQ78_06505	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_06535	COG0860	N-Acetylmuramoyl-L-alanine amidase
JSQ78_06535	COG2247	cell wall binding repeat
JSQ78_06540	COG0587	DNA-directed DNA polymerase activity
JSQ78_06550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JSQ78_06580	COG1132	(ABC) transporter
JSQ78_06595	COG0138	bifunctional purine biosynthesis protein purh
JSQ78_06610	COG2838	Isocitrate dehydrogenase
JSQ78_06630	COG0045	succinate-CoA ligase (ADP-forming) activity
JSQ78_06670	COG0584	glycerophosphoryl diester phosphodiesterase
JSQ78_06690	COG0385	Bile acid
JSQ78_06695	COG0822	iron-sulfur transferase activity
JSQ78_06710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JSQ78_06710	COG0519	Catalyzes the synthesis of GMP from XMP
JSQ78_06725	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JSQ78_06785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JSQ78_06810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JSQ78_06820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JSQ78_06830	COG0736	holo-[acyl-carrier-protein] synthase activity
JSQ78_06835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JSQ78_06840	COG1072	(Pantothenic acid kinase))
JSQ78_06855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JSQ78_06860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JSQ78_06865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JSQ78_06880	COG0101	tRNA pseudouridine synthase activity
JSQ78_06885	COG3387	PFAM Glycoside hydrolase 15-related
JSQ78_06890	COG0203	ribosomal protein L17
JSQ78_06895	COG0202	RNA polymerase activity
JSQ78_06900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JSQ78_06905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JSQ78_06915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JSQ78_06925	COG0246	Mannitol dehydrogenase
JSQ78_06930	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JSQ78_06950	COG1131	(ABC) transporter
JSQ78_06955	COG4133	protoheme IX ABC transporter activity
JSQ78_07000	COG0024	Methionine aminopeptidase
JSQ78_07005	COG0563	adenylate kinase activity
JSQ78_07015	COG0200	Binds to the 23S rRNA
JSQ78_07020	COG1841	ribosomal large subunit assembly
JSQ78_07025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JSQ78_07030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JSQ78_07035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JSQ78_07040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JSQ78_07045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JSQ78_07050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JSQ78_07055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JSQ78_07060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JSQ78_07065	COG0255	Belongs to the universal ribosomal protein uL29 family
JSQ78_07070	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JSQ78_07075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JSQ78_07080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JSQ78_07085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JSQ78_07090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JSQ78_07095	COG0089	rRNA binding
JSQ78_07100	COG0088	Forms part of the polypeptide exit tunnel
JSQ78_07105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JSQ78_07110	COG0051	transcription antitermination factor activity, RNA binding
JSQ78_07115	COG0010	Belongs to the arginase family
JSQ78_07135	COG1228	amidohydrolase
JSQ78_07140	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JSQ78_07145	COG2986	histidine ammonia-lyase
JSQ78_07190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JSQ78_07195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JSQ78_07200	COG0049	tRNA binding
JSQ78_07205	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JSQ78_07270	COG0515	serine threonine protein kinase
JSQ78_07270	COG2815	serine threonine protein kinase
JSQ78_07280	COG0631	protein serine/threonine phosphatase activity
JSQ78_07300	COG0714	Associated with various cellular activities
JSQ78_07315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JSQ78_07320	COG0085	RNA polymerase activity
JSQ78_07350	COG0667	Aldo Keto reductase
JSQ78_07405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JSQ78_07430	COG3655	Transcriptional regulator
JSQ78_07445	COG1748	Saccharopine dehydrogenase
JSQ78_07455	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JSQ78_07470	COG2205	protein histidine kinase activity
JSQ78_07475	COG0745	RESPONSE REGULATOR receiver
JSQ78_07480	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
JSQ78_07485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JSQ78_07505	COG1316	TRANSCRIPTIONal
JSQ78_07515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JSQ78_07520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JSQ78_07525	COG0302	gtp cyclohydrolase
JSQ78_07530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JSQ78_07550	COG0037	tRNA processing
JSQ78_07555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JSQ78_07620	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JSQ78_07665	COG1131	(ABC) transporter
JSQ78_07685	COG0860	N-Acetylmuramoyl-L-alanine amidase
JSQ78_07685	COG2247	cell wall binding repeat
JSQ78_07695	COG1253	flavin adenine dinucleotide binding
JSQ78_07710	COG2267	carboxylic ester hydrolase activity
JSQ78_07720	COG0028	Belongs to the TPP enzyme family
JSQ78_07730	COG2233	PERMEase
JSQ78_07735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JSQ78_07740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_07775	COG2814	Major facilitator Superfamily
JSQ78_07795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JSQ78_07800	COG2086	electron transfer activity
JSQ78_07810	COG1024	Enoyl-CoA hydratase
JSQ78_07815	COG1024	Enoyl-CoA hydratase
JSQ78_07815	COG1250	3-hydroxyacyl-CoA dehydrogenase
JSQ78_07820	COG1960	acyl-CoA dehydrogenase activity
JSQ78_07830	COG1960	acyl-CoA dehydrogenase activity
JSQ78_07835	COG0183	Belongs to the thiolase family
JSQ78_07840	COG0386	Belongs to the glutathione peroxidase family
JSQ78_07850	COG1063	alcohol dehydrogenase
JSQ78_07860	COG0640	Transcriptional regulator
JSQ78_07870	COG0604	alcohol dehydrogenase
JSQ78_07870	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_07870	COG3321	synthase
JSQ78_07890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JSQ78_07895	COG0318	PFAM AMP-dependent synthetase and ligase
JSQ78_07900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JSQ78_07915	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_07930	COG2026	Addiction module toxin, RelE StbE family
JSQ78_07965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JSQ78_07970	COG0477	Major facilitator Superfamily
JSQ78_07990	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JSQ78_07995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JSQ78_08000	COG1802	Transcriptional regulator
JSQ78_08015	COG0596	Alpha beta hydrolase
JSQ78_08020	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_08030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_08035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JSQ78_08065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JSQ78_08090	COG0167	dihydroorotate dehydrogenase activity
JSQ78_08095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JSQ78_08100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JSQ78_08105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JSQ78_08115	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JSQ78_08135	COG1802	Transcriptional regulator
JSQ78_08140	COG0477	Major facilitator Superfamily
JSQ78_08155	COG0235	Class ii aldolase
JSQ78_08170	COG3622	Belongs to the hyi family
JSQ78_08175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JSQ78_08180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JSQ78_08210	COG0477	Major facilitator Superfamily
JSQ78_08240	COG1454	alcohol dehydrogenase
JSQ78_08250	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_08320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JSQ78_08325	COG0765	amino acid transport
JSQ78_08330	COG1126	abc transporter atp-binding protein
JSQ78_08335	COG0673	inositol 2-dehydrogenase activity
JSQ78_08340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JSQ78_08365	COG3177	Filamentation induced by cAMP protein fic
JSQ78_08435	COG1305	Transglutaminase-like
JSQ78_08450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JSQ78_08480	COG0235	Class ii aldolase
JSQ78_08490	COG1172	Belongs to the binding-protein-dependent transport system permease family
JSQ78_08495	COG1129	ABC transporter
JSQ78_08505	COG1349	DNA-binding transcription factor activity
JSQ78_08520	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_08520	COG3347	Dehydrogenase
JSQ78_08525	COG1070	Carbohydrate kinase
JSQ78_08530	COG0823	Involved in the tonB-independent uptake of proteins
JSQ78_08530	COG1506	peptidase
JSQ78_08535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JSQ78_08540	COG0438	transferase activity, transferring glycosyl groups
JSQ78_08545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JSQ78_08565	COG1834	amidinotransferase
JSQ78_08610	COG0494	nUDIX hydrolase
JSQ78_08630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JSQ78_08650	COG1136	(ABC) transporter
JSQ78_08660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_08665	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_08685	COG0406	alpha-ribazole phosphatase activity
JSQ78_08700	COG2364	Membrane
JSQ78_08705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_08725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JSQ78_08730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JSQ78_08735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JSQ78_08750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JSQ78_08755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JSQ78_08760	COG1121	(ABC) transporter
JSQ78_08765	COG0803	Belongs to the bacterial solute-binding protein 9 family
JSQ78_08775	COG0508	dehydrogenase complex catalyzes the overall conversion of
JSQ78_08780	COG0022	dehydrogenase e1 component
JSQ78_08790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JSQ78_08795	COG1950	PFAM Membrane protein of
JSQ78_08815	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JSQ78_08820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JSQ78_08830	COG0753	catalase activity
JSQ78_08880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JSQ78_08900	COG0305	Participates in initiation and elongation during chromosome replication
JSQ78_08905	COG0359	binds to the 23S rRNA
JSQ78_08910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JSQ78_08920	COG0360	Binds together with S18 to 16S ribosomal RNA
JSQ78_08925	COG0617	tRNA 3'-terminal CCA addition
JSQ78_08950	COG3118	belongs to the thioredoxin family
JSQ78_08960	COG1192	Involved in chromosome partitioning
JSQ78_08965	COG0357	Ribosomal RNA small subunit methyltransferase G
JSQ78_08975	COG0706	membrane insertase activity
JSQ78_08980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JSQ78_08990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JSQ78_08995	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JSQ78_09000	COG0592	DNA-directed DNA polymerase activity
JSQ78_09005	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
JSQ78_09010	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JSQ78_09015	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
JSQ78_09020	COG2186	Transcriptional regulator
JSQ78_09030	COG2084	Dehydrogenase
JSQ78_09035	COG2610	gluconate transmembrane transporter activity
JSQ78_09040	COG0187	DNA topoisomerase II activity
JSQ78_09045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JSQ78_09070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JSQ78_09095	COG0705	Rhomboid family
JSQ78_09105	COG3764	Sortase (surface protein transpeptidase)
JSQ78_09120	COG0515	serine threonine protein kinase
JSQ78_09120	COG2815	serine threonine protein kinase
JSQ78_09125	COG0515	serine threonine protein kinase
JSQ78_09145	COG1716	ATPase activity
JSQ78_09165	COG0477	Major facilitator Superfamily
JSQ78_09170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JSQ78_09175	COG0006	proline dipeptidase activity
JSQ78_09180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JSQ78_09195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JSQ78_09255	COG1609	Transcriptional regulator
JSQ78_09260	COG1653	transport
JSQ78_09265	COG1175	transmembrane transport
JSQ78_09270	COG0395	ABC-type sugar transport system, permease component
JSQ78_09285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JSQ78_09290	COG3268	Saccharopine dehydrogenase
JSQ78_09305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JSQ78_09310	COG3573	Dehydrogenase
JSQ78_09320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JSQ78_09325	COG0181	hydroxymethylbilane synthase activity
JSQ78_09345	COG0488	(ABC) transporter
JSQ78_09355	COG0113	porphobilinogen synthase activity
JSQ78_09360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JSQ78_09370	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JSQ78_09375	COG0738	Major facilitator superfamily
JSQ78_09390	COG3590	peptidase
JSQ78_09410	COG2827	Endonuclease containing a URI domain
JSQ78_09420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JSQ78_09430	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JSQ78_09435	COG0142	geranyltranstransferase activity
JSQ78_09465	COG0702	epimerase
JSQ78_09475	COG1846	Transcriptional regulator
JSQ78_09485	COG1322	Protein conserved in bacteria
JSQ78_09545	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
JSQ78_09555	COG3655	Transcriptional regulator
JSQ78_09565	COG2066	Belongs to the glutaminase family
JSQ78_09570	COG2066	Belongs to the glutaminase family
JSQ78_09580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JSQ78_09585	COG1780	Probably involved in ribonucleotide reductase function
JSQ78_09595	COG0693	protein deglycase activity
JSQ78_09600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_09605	COG2318	DinB family
JSQ78_09610	COG1823	symporter activity
JSQ78_09635	COG0363	glucosamine-6-phosphate deaminase activity
JSQ78_09640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JSQ78_09665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JSQ78_09700	COG0395	ABC-type sugar transport system, permease component
JSQ78_09705	COG1175	transmembrane transport
JSQ78_09720	COG0542	response to heat
JSQ78_09725	COG2264	protein methyltransferase activity
JSQ78_09745	COG1024	Enoyl-CoA hydratase
JSQ78_09750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JSQ78_09755	COG2151	metal-sulfur cluster biosynthetic enzyme
JSQ78_09760	COG3396	Phenylacetate-CoA oxygenase
JSQ78_09765	COG3460	Phenylacetate-CoA oxygenase
JSQ78_09770	COG3396	Phenylacetate-CoA oxygenase
JSQ78_09780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JSQ78_09785	COG1309	transcriptional regulator
JSQ78_09790	COG1652	LysM domain
JSQ78_09795	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_09795	COG2030	dehydratase
JSQ78_09800	COG1250	3-hydroxyacyl-CoA dehydrogenase
JSQ78_09805	COG1024	Enoyl-CoA hydratase
JSQ78_09810	COG0183	Belongs to the thiolase family
JSQ78_09840	COG1960	acyl-CoA dehydrogenase activity
JSQ78_09850	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JSQ78_09855	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
JSQ78_09875	COG0717	Belongs to the dCTP deaminase family
JSQ78_09930	COG0443	Heat shock 70 kDa protein
JSQ78_09940	COG0484	heat shock protein binding
JSQ78_09945	COG0789	Transcriptional regulator
JSQ78_09975	COG2205	protein histidine kinase activity
JSQ78_09990	COG0596	Alpha beta hydrolase
JSQ78_10020	COG0739	heme binding
JSQ78_10020	COG0741	lytic transglycosylase activity
JSQ78_10020	COG1196	nuclear chromosome segregation
JSQ78_10035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JSQ78_10060	COG0785	Cytochrome C biogenesis protein
JSQ78_10065	COG1333	cytochrome c biogenesis protein
JSQ78_10075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JSQ78_10115	COG1619	proteins homologs of microcin C7 resistance protein MccF
JSQ78_10155	COG0542	response to heat
JSQ78_10160	COG2814	Major facilitator Superfamily
JSQ78_10170	COG0513	Belongs to the DEAD box helicase family
JSQ78_10175	COG1940	carbohydrate kinase activity
JSQ78_10240	COG1131	(ABC) transporter
JSQ78_10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JSQ78_10255	COG1668	transmembrane transport
JSQ78_10260	COG4152	abc transporter atp-binding protein
JSQ78_10275	COG0640	Transcriptional regulator
JSQ78_10290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JSQ78_10300	COG2197	response regulator
JSQ78_10350	COG2011	ABC-type metal ion transport system permease component
JSQ78_10400	COG0477	Major facilitator Superfamily
JSQ78_10455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JSQ78_10460	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_10465	COG0686	Belongs to the AlaDH PNT family
JSQ78_10485	COG0659	secondary active sulfate transmembrane transporter activity
JSQ78_10500	COG2239	Acts as a magnesium transporter
JSQ78_10530	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JSQ78_10540	COG1362	aminopeptidase activity
JSQ78_10555	COG1733	regulation of RNA biosynthetic process
JSQ78_10565	COG5416	Lipopolysaccharide assembly protein A domain
JSQ78_10610	COG4221	oxidoreductase activity
JSQ78_10620	COG1476	TRANSCRIPTIONal
JSQ78_10660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JSQ78_10690	COG2072	flavoprotein involved in K transport
JSQ78_10730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JSQ78_10735	COG1201	RNA secondary structure unwinding
JSQ78_10795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JSQ78_10805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JSQ78_10845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JSQ78_10855	COG0047	phosphoribosylformylglycinamidine synthase activity
JSQ78_10870	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JSQ78_10875	COG0151	Belongs to the GarS family
JSQ78_10900	COG2031	fatty acid transporter
JSQ78_10905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JSQ78_10925	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_10935	COG1063	alcohol dehydrogenase
JSQ78_10940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JSQ78_10960	COG1760	l-serine dehydratase
JSQ78_10970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JSQ78_10975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JSQ78_10980	COG0789	Transcriptional regulator
JSQ78_10985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JSQ78_10995	COG0513	Belongs to the DEAD box helicase family
JSQ78_11005	COG0514	ATP-dependent DNA helicase (RecQ)
JSQ78_11035	COG0477	Major facilitator Superfamily
JSQ78_11040	COG1876	peptidase activity
JSQ78_11065	COG2076	Multidrug Resistance protein
JSQ78_11070	COG2076	Multidrug Resistance protein
JSQ78_11080	COG0033	Phosphoglucomutase
JSQ78_11085	COG0076	glutamate decarboxylase activity
JSQ78_11100	COG1136	(ABC) transporter
JSQ78_11115	COG0077	Prephenate dehydratase
JSQ78_11120	COG1597	lipid kinase activity
JSQ78_11125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JSQ78_11130	COG0561	phosphatase activity
JSQ78_11150	COG1278	Cold shock
JSQ78_11190	COG0277	FAD linked oxidase domain protein
JSQ78_11195	COG0406	alpha-ribazole phosphatase activity
JSQ78_11200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JSQ78_11210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JSQ78_11225	COG0519	Catalyzes the synthesis of GMP from XMP
JSQ78_11225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JSQ78_11240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JSQ78_11245	COG0590	tRNA wobble adenosine to inosine editing
JSQ78_11270	COG3012	SEC-C Motif Domain Protein
JSQ78_11275	COG0569	domain protein
JSQ78_11280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JSQ78_11300	COG0017	Asparaginyl-tRNA synthetase
JSQ78_11310	COG0406	alpha-ribazole phosphatase activity
JSQ78_11320	COG0785	Cytochrome C biogenesis protein
JSQ78_11330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JSQ78_11340	COG4948	Mandelate Racemase Muconate Lactonizing
JSQ78_11375	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JSQ78_11400	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JSQ78_11405	COG0300	oxidoreductase activity
JSQ78_11410	COG0628	permease
JSQ78_11415	COG2326	polyphosphate kinase activity
JSQ78_11425	COG2226	methyltransferase
JSQ78_11430	COG0142	geranyltranstransferase activity
JSQ78_11445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JSQ78_11450	COG1666	GTP binding
JSQ78_11470	COG0739	heme binding
JSQ78_11475	COG0366	Alpha amylase catalytic
JSQ78_11480	COG2182	Extracellular solute-binding protein
JSQ78_11485	COG1175	transmembrane transport
JSQ78_11490	COG3833	ABC-type maltose transport systems, permease component
JSQ78_11510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JSQ78_11530	COG2030	dehydratase
JSQ78_11540	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JSQ78_11550	COG2197	response regulator
JSQ78_11570	COG0657	acetylesterase activity
JSQ78_11575	COG0436	Aminotransferase
JSQ78_11595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JSQ78_11600	COG0081	regulation of translation
JSQ78_11610	COG2197	response regulator
JSQ78_11620	COG0747	negative chemotaxis
JSQ78_11625	COG0601	transmembrane transport
JSQ78_11630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JSQ78_11635	COG4172	Belongs to the ABC transporter superfamily
JSQ78_11665	COG0745	RESPONSE REGULATOR receiver
JSQ78_11670	COG2205	protein histidine kinase activity
JSQ78_11675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JSQ78_11680	COG0222	ribosome binding
JSQ78_11690	COG1132	(ABC) transporter
JSQ78_11705	COG0626	cystathionine gamma-synthase activity
JSQ78_11710	COG0477	Major facilitator Superfamily
JSQ78_11720	COG0402	S-adenosylhomocysteine deaminase activity
JSQ78_11725	COG2814	Major facilitator Superfamily
JSQ78_11730	COG0433	COG0433 Predicted ATPase
JSQ78_11755	COG0745	RESPONSE REGULATOR receiver
JSQ78_11775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JSQ78_11795	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JSQ78_11815	COG0579	oxidoreductase
JSQ78_11825	COG1435	thymidine kinase activity
JSQ78_11860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JSQ78_11890	COG1754	DNA topoisomerase type I activity
JSQ78_11890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JSQ78_11895	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JSQ78_11900	COG0470	DNA polymerase III
JSQ78_11920	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
JSQ78_11935	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
JSQ78_11945	COG1335	isochorismatase
JSQ78_11950	COG2409	Drug exporters of the RND superfamily
JSQ78_11960	COG1132	(ABC) transporter
JSQ78_11970	COG1131	(ABC) transporter
JSQ78_11990	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JSQ78_12000	COG0477	Major facilitator Superfamily
JSQ78_12005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JSQ78_12010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JSQ78_12010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JSQ78_12030	COG0180	Tryptophanyl-tRNA synthetase
JSQ78_12045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JSQ78_12050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JSQ78_12055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JSQ78_12065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JSQ78_12070	COG1053	succinate dehydrogenase
JSQ78_12080	COG2009	succinate dehydrogenase
JSQ78_12085	COG0438	transferase activity, transferring glycosyl groups
JSQ78_12095	COG1744	ABC transporter substrate-binding protein PnrA-like
JSQ78_12105	COG3845	ABC transporter
JSQ78_12110	COG4603	Belongs to the binding-protein-dependent transport system permease family
JSQ78_12115	COG1079	Belongs to the binding-protein-dependent transport system permease family
JSQ78_12140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JSQ78_12145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JSQ78_12165	COG4770	biotin carboxylase activity
JSQ78_12195	COG0424	maF-like protein
JSQ78_12200	COG0039	L-malate dehydrogenase activity
JSQ78_12205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JSQ78_12225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JSQ78_12225	COG2755	lipolytic protein G-D-S-L family
JSQ78_12230	COG2755	lipolytic protein G-D-S-L family
JSQ78_12230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JSQ78_12240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JSQ78_12255	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JSQ78_12270	COG1316	TRANSCRIPTIONal
JSQ78_12275	COG1215	transferase activity, transferring glycosyl groups
JSQ78_12300	COG1215	transferase activity, transferring glycosyl groups
JSQ78_12360	COG1216	Glycosyl transferase, family 2
JSQ78_12365	COG1960	acyl-CoA dehydrogenase activity
JSQ78_12405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JSQ78_12410	COG1088	dTDP-glucose 4,6-dehydratase activity
JSQ78_12425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JSQ78_12445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JSQ78_12450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JSQ78_12460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JSQ78_12485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JSQ78_12495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JSQ78_12500	COG2084	Dehydrogenase
JSQ78_12525	COG1028	Short-chain dehydrogenase reductase Sdr
JSQ78_12530	COG1063	alcohol dehydrogenase
JSQ78_12535	COG3265	gluconokinase activity
JSQ78_12540	COG2610	gluconate transmembrane transporter activity
JSQ78_12545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JSQ78_12550	COG0193	aminoacyl-tRNA hydrolase activity
JSQ78_12565	COG3956	TIGRFAM MazG family protein
JSQ78_12605	COG0124	histidyl-tRNA synthetase
JSQ78_12610	COG0148	phosphopyruvate hydratase activity
JSQ78_12645	COG3214	Protein conserved in bacteria
JSQ78_12655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JSQ78_12660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JSQ78_12670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JSQ78_12730	COG0582	viral genome integration into host DNA
JSQ78_12790	COG0577	efflux transmembrane transporter activity
JSQ78_12790	COG1136	(ABC) transporter
JSQ78_12890	COG2409	Drug exporters of the RND superfamily
JSQ78_12900	COG0318	PFAM AMP-dependent synthetase and ligase
JSQ78_12905	COG1063	alcohol dehydrogenase
JSQ78_12910	COG1609	Transcriptional regulator
JSQ78_12915	COG1082	Xylose isomerase domain protein TIM barrel
JSQ78_12920	COG0129	dihydroxy-acid dehydratase activity
JSQ78_12930	COG0440	acetolactate synthase activity
JSQ78_12935	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JSQ78_12940	COG0723	plastoquinol--plastocyanin reductase activity
JSQ78_12980	COG0477	Major facilitator Superfamily
JSQ78_12990	COG2205	protein histidine kinase activity
JSQ78_13000	COG0473	3-isopropylmalate dehydrogenase activity
JSQ78_13005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JSQ78_13010	COG0179	Fumarylacetoacetate (FAA) hydrolase
JSQ78_13025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JSQ78_13030	COG0492	ferredoxin-NADP+ reductase activity
JSQ78_13075	COG3971	2-oxopent-4-enoate hydratase activity
JSQ78_13085	COG1012	belongs to the aldehyde dehydrogenase family
JSQ78_13100	COG0477	Major facilitator Superfamily
JSQ78_13120	COG0569	domain protein
JSQ78_13120	COG0189	ligase activity
JSQ78_13125	COG4067	protein conserved in archaea
JSQ78_13125	COG0189	ligase activity
JSQ78_13170	COG0039	L-malate dehydrogenase activity
JSQ78_13175	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JSQ78_13180	COG0066	3-isopropylmalate dehydratase activity
JSQ78_13185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JSQ78_13195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JSQ78_13200	COG1181	Belongs to the D-alanine--D-alanine ligase family
JSQ78_13230	COG1254	Belongs to the acylphosphatase family
JSQ78_13245	COG0012	GTP binding
JSQ78_13260	COG0596	Alpha beta hydrolase
JSQ78_13275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JSQ78_13280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JSQ78_13285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JSQ78_13290	COG0798	PFAM Bile acid sodium symporter
JSQ78_13295	COG0492	ferredoxin-NADP+ reductase activity
JSQ78_13315	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JSQ78_13335	COG1058	Belongs to the CinA family
JSQ78_13335	COG1546	Belongs to the CinA family
JSQ78_13350	COG1253	flavin adenine dinucleotide binding
JSQ78_13375	COG0488	(ABC) transporter
JSQ78_13400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JSQ78_13450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JSQ78_13480	COG2814	Major facilitator Superfamily
JSQ78_13500	COG0419	ATPase involved in DNA repair
JSQ78_13510	COG2111	Na H antiporter
JSQ78_13510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JSQ78_13515	COG1006	Multisubunit Na H antiporter MnhC subunit
JSQ78_13520	COG0651	ATP synthesis coupled electron transport
JSQ78_13530	COG2212	antiporter activity
JSQ78_13535	COG1320	monovalent cation:proton antiporter activity
JSQ78_13540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JSQ78_13545	COG0509	glycine decarboxylation via glycine cleavage system
JSQ78_13550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JSQ78_13550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JSQ78_13565	COG4166	transmembrane transport
JSQ78_13575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JSQ78_13590	COG1217	gtp-binding protein TYPA
JSQ78_13595	COG0431	NADPH-dependent FMN reductase
JSQ78_13600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JSQ78_13620	COG2252	PERMEase
JSQ78_13635	COG2171	N-acyltransferase activity
JSQ78_13640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JSQ78_13660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JSQ78_13675	COG2239	Acts as a magnesium transporter
JSQ78_13695	COG0006	proline dipeptidase activity