locus-tag	class	description
C1N71_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C1N71_00015	ENOG4108J5G	6-phosphogluconate dehydrogenase
C1N71_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C1N71_00025	ENOG4105K7N	UPF0232 protein
C1N71_00035	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C1N71_00040	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C1N71_00060	ENOG4105EEI	dihydropteroate synthase
C1N71_00070	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C1N71_00110	ENOG4105ZJT	Cell division protein CrgA
C1N71_00130	ENOG4107TPY	serine threonine protein kinase
C1N71_00135	ENOG4105CJN	penicillin-binding protein
C1N71_00170	ENOG4105E2A	Dehydrogenase
C1N71_00175	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C1N71_00200	ENOG4105C02	permease
C1N71_00215	ENOG4108T5E	Copper resistance protein
C1N71_00220	ENOG41080T7	secreted protein
C1N71_00225	ENOG4105DBE	peroxidase
C1N71_00235	ENOG4105C1G	acyl-Coa dehydrogenase
C1N71_00240	ENOG4105C26	Dehydrogenase
C1N71_00265	ENOG4107YCR	Transcriptional regulator, ARSR family
C1N71_00270	ENOG4105FKQ	transcriptional regulator
C1N71_00295	ENOG4108JQ7	(ABC) transporter
C1N71_00320	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
C1N71_00365	ENOG4107YCR	Transcriptional regulator, ARSR family
C1N71_00380	ENOG4108YZG	isomerase
C1N71_00385	ENOG4105ETE	Transcriptional regulator (LacI family
C1N71_00410	ENOG4105FQP	Beta-lactamase
C1N71_00415	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C1N71_00430	ENOG4107QSI	ABC, transporter
C1N71_00460	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C1N71_00470	ENOG4105CHR	reductase
C1N71_00475	ENOG4105CSH	Transporter
C1N71_00495	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C1N71_00500	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C1N71_00505	ENOG4107JTW	chlorite dismutase
C1N71_00525	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C1N71_00540	ENOG4105EMN	RNA polymerase sigma factor
C1N71_00585	ENOG4105XEV	csbD-like
C1N71_00590	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C1N71_00595	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C1N71_00610	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C1N71_00635	ENOG4106517	Short-chain dehydrogenase reductase Sdr
C1N71_00675	ENOG4105CSH	Transporter
C1N71_00685	ENOG4105C7K	acetolactate synthase
C1N71_00700	ENOG4105CSH	Transporter
C1N71_00710	ENOG4105C7K	acetolactate synthase
C1N71_00715	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C1N71_00720	ENOG4105FDP	GntR family transcriptional regulator
C1N71_00730	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C1N71_00745	ENOG4105C50	Binding-protein-dependent transport systems, inner membrane component
C1N71_00780	ENOG4105C85	amino acid
C1N71_00800	ENOG4105CHR	reductase
C1N71_00810	ENOG4105PGM	cation diffusion facilitator family transporter
C1N71_00835	ENOG4105CJP	fad dependent oxidoreductase
C1N71_00860	ENOG41073TP	transcriptional regulator
C1N71_00870	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
C1N71_00920	ENOG4105CPC	Aldo Keto reductase
C1N71_00940	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
C1N71_00940	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
C1N71_00945	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
C1N71_00955	ENOG4105EPJ	extracellular solute-binding protein family 1
C1N71_00960	ENOG4105ETE	Transcriptional regulator (LacI family
C1N71_00965	ENOG4105CG3	alpha amylase, catalytic region
C1N71_00975	ENOG4105DKT	Transcriptional regulator
C1N71_00980	ENOG4105CNN	ABC, transporter
C1N71_00990	ENOG4105C2J	ABC transporter
C1N71_00995	ENOG4105C2X	Arabinose 5-phosphate isomerase
C1N71_01005	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C1N71_01025	ENOG4105EUB	pirin domain protein
C1N71_01040	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C1N71_01050	ENOG4108SU4	UPF0309 protein
C1N71_01055	ENOG4105FDP	GntR family transcriptional regulator
C1N71_01065	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
C1N71_01150	ENOG4105DXB	Major Facilitator superfamily
C1N71_01170	ENOG4105D52	delta-aminolevulinic acid dehydratase
C1N71_01175	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C1N71_01185	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
C1N71_01190	ENOG4106UW1	Major Facilitator superfamily
C1N71_01200	ENOG4105CIG	ABC transporter
C1N71_01205	ENOG4105DIM	ABC transporter
C1N71_01210	ENOG4105UQX	Mate efflux family protein
C1N71_01225	ENOG4105CSH	Transporter
C1N71_01235	ENOG4105VBF	alkaline shock protein
C1N71_01240	ENOG4105C9K	Endothelin-converting enzyme 1
C1N71_01270	ENOG4108TGP	Thioesterase superfamily protein
C1N71_01280	ENOG4105C26	Dehydrogenase
C1N71_01295	ENOG4107TB5	TRANSCRIPTIONal
C1N71_01300	ENOG4105D2S	major facilitator superfamily
C1N71_01315	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C1N71_01330	ENOG4105CFG	Acts as a chaperone (By similarity)
C1N71_01335	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1N71_01340	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C1N71_01345	ENOG4105KNI	merR family transcriptional Regulator
C1N71_01380	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C1N71_01405	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C1N71_01410	ENOG41090KN	UPF0303 protein
C1N71_01435	ENOG4105WH1	Two component transcriptional regulator luxr family
C1N71_01440	ENOG4105DKQ	ROK family
C1N71_01450	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
C1N71_01470	ENOG4105CGH	5'-nucleotidase
C1N71_01485	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C1N71_01520	ENOG4105RHA	ABC transporter, permease
C1N71_01525	ENOG4108IUX	(ABC) transporter
C1N71_01530	ENOG4105WH1	Two component transcriptional regulator luxr family
C1N71_01535	ENOG4105BZU	Histidine kinase
C1N71_01540	ENOG4105C9A	Phoh family
C1N71_01570	ENOG4105ETX	regulatoR
C1N71_01620	ENOG4107XSR	periplasmic solute binding protein
C1N71_01630	ENOG4105CC5	ABC transporter
C1N71_01635	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
C1N71_01645	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C1N71_01665	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C1N71_01735	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C1N71_01745	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C1N71_01750	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C1N71_01775	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C1N71_01800	ENOG4105CEY	Amp-dependent synthetase and ligase
C1N71_01805	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C1N71_01820	ENOG4105C8V	SAICAR synthetase
C1N71_01825	ENOG4105C12	Phosphoribosylglycinamide synthetase
C1N71_01835	ENOG4105C2W	permease
C1N71_01850	ENOG4105CQR	helicase
C1N71_01865	ENOG4105DFM	M18 family aminopeptidase
C1N71_01875	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C1N71_01890	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C1N71_01905	ENOG4105FB2	class II Aldolase
C1N71_01910	ENOG4105CNN	ABC, transporter
C1N71_01915	ENOG4105CNN	ABC, transporter
C1N71_01920	ENOG4105C2J	ABC transporter
C1N71_01935	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
C1N71_01950	ENOG4105DET	Rhamnulokinase
C1N71_01960	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C1N71_01965	ENOG4105CPQ	Dehydrogenase
C1N71_01975	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C1N71_01995	ENOG4105EJQ	L-serine dehydratase
C1N71_02015	ENOG41082CG	Protein CrcB homolog
C1N71_02020	ENOG4105C0X	amino acid
C1N71_02050	ENOG4107TXC	Transcriptional regulator
C1N71_02055	ENOG4105D7T	ABC transporter
C1N71_02065	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
C1N71_02070	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C1N71_02085	ENOG4105C1J	atp-dependent rna helicase
C1N71_02095	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C1N71_02110	ENOG4105CI0	Citrate lyase
C1N71_02120	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C1N71_02130	ENOG4108VXD	carboxy-peptidase
C1N71_02145	ENOG410814C	multidrug resistance protein
C1N71_02155	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
C1N71_02200	ENOG4107TE5	Lipid kinase
C1N71_02205	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C1N71_02210	ENOG4108KP7	hydrolase
C1N71_02220	ENOG4108KGH	TRANSCRIPTIONal
C1N71_02255	ENOG4105E39	Enoyl-CoA hydratase
C1N71_02260	ENOG4105E39	Enoyl-CoA hydratase
C1N71_02265	ENOG4105VEQ	Cold shock protein
C1N71_02300	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
C1N71_02305	ENOG4105CHR	reductase
C1N71_02310	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
C1N71_02315	ENOG4105DQ4	alcohol dehydrogenase
C1N71_02360	ENOG4105DCF	alanine dehydrogenase
C1N71_02365	ENOG4105EW9	transcriptional regulator AsnC family
C1N71_02370	ENOG4108Z9K	Osmotically inducible protein
C1N71_02375	ENOG4105EEQ	Na H antiporter
C1N71_02405	ENOG4105CQB	FAD linked oxidase domain protein
C1N71_02410	ENOG4107TB6	phosphoglycerate mutase
C1N71_02430	ENOG4105JSC	dimethylmenaquinone methyltransferase
C1N71_02435	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C1N71_02440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C1N71_02445	ENOG4107RUE	extracellular solute-binding protein family 1
C1N71_02450	ENOG4105D38	putrescine abc transporter
C1N71_02455	ENOG4105F38	ABC transporter, permease
C1N71_02470	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C1N71_02480	ENOG41089BK	Glutamine amido-transferase
C1N71_02485	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
C1N71_02530	ENOG4105CPC	Aldo Keto reductase
C1N71_02540	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
C1N71_02545	ENOG4107QRT	dEAD DEAH box helicase
C1N71_02560	ENOG4107NHD	transcriptional regulator
C1N71_02565	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C1N71_02570	ENOG4108Z6B	deaminase
C1N71_02595	ENOG4105II7	pyrroline-5-carboxylate reductase
C1N71_02600	ENOG4105K5B	UPF0225 protein
C1N71_02605	ENOG4107ZYR	domain protein
C1N71_02635	ENOG4105C5S	asparaginyl-tRNA synthetase
C1N71_02675	ENOG4107QIV	Cytochrome c biogenesis protein
C1N71_02680	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
C1N71_02685	ENOG4105CRE	cytochrome C
C1N71_02690	ENOG4107TCW	O-succinylbenzoate synthase
C1N71_02715	ENOG4107SIQ	Naphthoate synthase
C1N71_02740	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C1N71_02745	ENOG4105CSR	polyphosphate kinase 2
C1N71_02755	ENOG4105E4F	Isochorismate synthase
C1N71_02760	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C1N71_02795	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C1N71_02800	ENOG4108VPT	UPF0234 protein
C1N71_02810	ENOG4105E4C	Lytic transglycosylase catalytic
C1N71_02815	ENOG4105CG3	alpha amylase, catalytic region
C1N71_02830	ENOG4107QN1	sodium solute
C1N71_02835	ENOG4105ECP	epimerase
C1N71_02850	ENOG410900P	UPF0336 protein
C1N71_02860	ENOG4107R4N	Cell wall formation (By similarity)
C1N71_02880	ENOG410683Z	Preprotein translocase SecE subunit
C1N71_02890	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C1N71_02895	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C1N71_02900	ENOG4105WH1	Two component transcriptional regulator luxr family
C1N71_02905	ENOG4105BZU	Histidine kinase
C1N71_02930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C1N71_02935	ENOG4105BZU	Histidine kinase
C1N71_02950	ENOG4108VZM	50s ribosomal protein L10
C1N71_02955	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C1N71_02965	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
C1N71_02970	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
C1N71_02975	ENOG4105BZ1	(ABC) transporter
C1N71_02980	ENOG4105E2R	ROK family
C1N71_02990	ENOG4108HWW	ABC transporter
C1N71_02995	ENOG4105DFW	ABC transporter
C1N71_03015	ENOG41079KZ	Major Facilitator Superfamily
C1N71_03020	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C1N71_03025	ENOG4105C2C	drug resistance transporter, Bcr CflA
C1N71_03035	ENOG4105D7A	ATP-binding protein
C1N71_03045	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C1N71_03050	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C1N71_03060	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C1N71_03080	ENOG4105CPC	Aldo Keto reductase
C1N71_03090	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C1N71_03095	ENOG4105CUB	amino acid
C1N71_03100	ENOG4105CFH	Aspartokinase
C1N71_03110	ENOG4105DWT	malate dehydrogenase (quinone)
C1N71_03120	ENOG4107104	thymidine kinase
C1N71_03135	ENOG4108JQC	penicillin-binding protein 1A
C1N71_03145	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C1N71_03210	ENOG4105M6F	mutator MutT protein
C1N71_03245	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C1N71_03250	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C1N71_03255	ENOG4105C6E	dna polymerase iii
C1N71_03270	ENOG4105DEF	Extracellular solute-binding protein, family 5
C1N71_03275	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C1N71_03280	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C1N71_03285	ENOG4108JQ6	ABC transporter
C1N71_03305	ENOG4108RWI	nicotinamidase
C1N71_03340	ENOG4105CJ1	ABC, transporter
C1N71_03355	ENOG4105EDK	PfkB domain protein
C1N71_03365	ENOG4105CSH	Transporter
C1N71_03375	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C1N71_03380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C1N71_03395	ENOG4105C31	Tryptophanyl-tRNA synthetase
C1N71_03410	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C1N71_03425	ENOG4105E33	succinate dehydrogenase
C1N71_03445	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C1N71_03450	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C1N71_03460	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C1N71_03465	ENOG4105DIH	basic membrane
C1N71_03475	ENOG4108JQ9	ABC transporter
C1N71_03480	ENOG4105UIB	(ABC) transporter
C1N71_03510	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C1N71_03515	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
C1N71_03525	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
C1N71_03545	ENOG4106F60	Histidine kinase
C1N71_03550	ENOG4105F44	Two component transcriptional regulator, winged helix family
C1N71_03575	ENOG4108JIK	carboxylase
C1N71_03595	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C1N71_03600	ENOG4107WR6	Maf-like protein
C1N71_03610	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C1N71_03630	ENOG4105D8K	carboxyl transferase
C1N71_03635	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C1N71_03645	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C1N71_03665	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C1N71_03700	ENOG4105K4I	Scp-like extracellular
C1N71_03740	ENOG4105MFV	ABC-2 type transporter
C1N71_03745	ENOG4105EY8	ABC transporter
C1N71_03770	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C1N71_03780	ENOG4105C1G	acyl-Coa dehydrogenase
C1N71_03785	ENOG4105EIP	mannose-6-phosphate isomerase
C1N71_03790	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
C1N71_03815	ENOG4107QKV	phosphomannomutase
C1N71_03820	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C1N71_03850	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C1N71_03855	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C1N71_03865	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
C1N71_03875	ENOG4107QJT	sodium dicarboxylate symporter
C1N71_03880	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C1N71_03885	ENOG4108MRH	transcriptional regulatory protein
C1N71_03890	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
C1N71_03895	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C1N71_03905	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C1N71_03910	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C1N71_03930	ENOG4105CHR	reductase
C1N71_03940	ENOG4105CPQ	Dehydrogenase
C1N71_03945	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C1N71_03950	ENOG4105C6Z	Gluconate
C1N71_03955	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C1N71_03960	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C1N71_03975	ENOG4108IY2	MazG family
C1N71_04010	ENOG4105CUT	histidyl-tRNA synthetase
C1N71_04015	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C1N71_04040	ENOG41079KZ	Major Facilitator Superfamily
C1N71_04070	ENOG4105C7B	Threonine dehydratase
C1N71_04075	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C1N71_04085	ENOG4105T1M	mycothiol conjugate amidase mca
C1N71_04140	ENOG4105C5H	ABC transporter
C1N71_04185	ENOG4105EY0	Xylose isomerase domain protein TIM barrel
C1N71_04190	ENOG4105C01	Dihydroxy-acid dehydratase
C1N71_04200	ENOG4108ZP8	Acetolactate synthase small subunit
C1N71_04205	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C1N71_04210	ENOG4105E2R	ROK family
C1N71_04280	ENOG41082VC	UPF0145 protein
C1N71_04285	ENOG4108JQ1	Dehydrogenase
C1N71_04300	ENOG4105C57	major facilitator superfamily
C1N71_04310	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C1N71_04315	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C1N71_04320	ENOG4105ERH	Fumarylacetoacetate hydrolase
C1N71_04325	ENOG4107ZR7	Membrane
C1N71_04330	ENOG4105CSV	Glutaminase
C1N71_04340	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C1N71_04345	ENOG4105C3M	thioredoxin reductase
C1N71_04365	ENOG4105EMU	Dehydrogenase
C1N71_04400	ENOG4105C26	Dehydrogenase
C1N71_04410	ENOG4105ERH	Fumarylacetoacetate hydrolase
C1N71_04415	ENOG4105CSH	Transporter
C1N71_04420	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C1N71_04425	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C1N71_04440	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C1N71_04515	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C1N71_04520	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C1N71_04525	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C1N71_04545	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
C1N71_04575	ENOG4107ZXU	DSBA oxidoreductase
C1N71_04580	ENOG4105C3G	gtp-binding protein
C1N71_04590	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C1N71_04615	ENOG4105ECR	NmrA family
C1N71_04620	ENOG4105KVH	Transcriptional regulator
C1N71_04635	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C1N71_04640	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C1N71_04685	ENOG4108V06	Glutathione peroxidase
C1N71_04690	ENOG4105D65	subunit l
C1N71_04695	ENOG4105MKQ	Monovalent cation H antiporter subunit C
C1N71_04700	ENOG4108JPZ	Monovalent cation H antiporter subunit D
C1N71_04715	ENOG4105KJM	monovalent cation h antiporter subunit g
C1N71_04720	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C1N71_04725	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C1N71_04730	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1N71_04770	ENOG4108JQ6	ABC transporter
C1N71_04775	ENOG4105CI3	gtp-binding protein typa
C1N71_04790	ENOG4108UZX	fmn reductase
C1N71_04795	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
C1N71_04800	ENOG4108Z4U	Ferredoxin
C1N71_04815	ENOG4105C7N	Xanthine uracil vitamin C permease
C1N71_04835	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
C1N71_04840	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
C1N71_04855	ENOG4107ZBN	O-methyltransferase
C1N71_04865	ENOG4107RBJ	symporter
C1N71_04870	ENOG4105CVK	Glutamate decarboxylase
C1N71_04910	ENOG4107T6F	Xaa-Pro aminopeptidase
C1N71_04915	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
C1N71_04935	ENOG4105CEY	Amp-dependent synthetase and ligase
C1N71_04965	ENOG4105DB7	PHP domain protein
C1N71_04975	ENOG4105C1J	atp-dependent rna helicase
C1N71_05020	ENOG4105C0H	protease
C1N71_05025	ENOG4105DJZ	UPF0182 protein
C1N71_05050	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C1N71_05060	ENOG4105C0H	protease
C1N71_05065	ENOG4107SJB	teichoic acid biosynthesis
C1N71_05085	ENOG4105EY8	ABC transporter
C1N71_05095	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C1N71_05100	ENOG4105DA5	(ABC) transporter
C1N71_05125	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C1N71_05130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C1N71_05135	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C1N71_05155	ENOG4105CWX	Alpha-1,2-mannosidase
C1N71_05160	ENOG4107XFB	conserved TRANSMEMBRANE PROTEIN
C1N71_05170	ENOG4105EMU	Dehydrogenase
C1N71_05185	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
C1N71_05200	ENOG4105FDK	ABC transporter
C1N71_05250	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
C1N71_05275	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C1N71_05280	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C1N71_05290	ENOG4105CAK	Cell division ATP-binding protein ftsE
C1N71_05295	ENOG4107RYD	Part of the ABC transporter FtsEX involved in cellular division (By similarity)
C1N71_05300	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C1N71_05320	ENOG4105VFE	sira family
C1N71_05330	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C1N71_05335	ENOG4107TK4	histidinol-phosphate phosphatase
C1N71_05350	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C1N71_05355	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C1N71_05360	ENOG4105EMN	RNA polymerase sigma factor
C1N71_05375	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C1N71_05385	ENOG4105C2M	dna polymerase I
C1N71_05410	ENOG4105DWV	Homoserine O-trans-acetylase
C1N71_05420	ENOG4108TGC	Acyltransferase
C1N71_05445	ENOG41062IY	50S ribosomal protein L32
C1N71_05450	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C1N71_05455	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C1N71_05465	ENOG4105C26	Dehydrogenase
C1N71_05500	ENOG4107RNR	Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA (By similarity)
C1N71_05505	ENOG4105NX3	Membrane
C1N71_05525	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C1N71_05545	ENOG4105DYW	oxidoreductase
C1N71_05550	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
C1N71_05555	ENOG4105K5M	30s ribosomal protein S16
C1N71_05560	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C1N71_05575	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C1N71_05585	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C1N71_05605	ENOG41080R2	UPF0102 protein
C1N71_05610	ENOG4105C0P	Mg chelatase subunit ChlI
C1N71_05635	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C1N71_05650	ENOG4105CE9	30S ribosomal protein S2
C1N71_05655	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C1N71_05660	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C1N71_05665	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C1N71_05700	ENOG4105K63	Thioredoxin
C1N71_05710	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C1N71_05715	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
C1N71_05735	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C1N71_05740	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C1N71_05750	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C1N71_05765	ENOG4107VWK	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C1N71_05795	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C1N71_05800	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C1N71_05815	ENOG4105DYW	oxidoreductase
C1N71_05830	ENOG4105PGM	cation diffusion facilitator family transporter
C1N71_05840	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
C1N71_05845	ENOG4108JJB	ABC transporter
C1N71_05885	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C1N71_05900	ENOG4107T5V	SNARE associated Golgi
C1N71_05935	ENOG4105C26	Dehydrogenase
C1N71_05945	ENOG4105C29	acyl-CoA thioesterase
C1N71_05955	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
C1N71_05965	ENOG4105D8X	mechanosensitive ion channel
C1N71_05975	ENOG4105MC2	DSBA oxidoreductase
C1N71_05980	ENOG4108YZG	isomerase
C1N71_06020	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C1N71_06035	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C1N71_06070	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C1N71_06085	ENOG4105RNG	membrane
C1N71_06090	ENOG4105K6V	RNA polymerase
C1N71_06100	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C1N71_06105	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C1N71_06110	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C1N71_06120	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C1N71_06125	ENOG4105E0A	ABC, transporter
C1N71_06135	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
C1N71_06140	ENOG4105DGW	oligopeptidase A
C1N71_06155	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
C1N71_06165	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C1N71_06180	ENOG4105CSH	Transporter
C1N71_06185	ENOG41067SE	Tetr family transcriptional regulator
C1N71_06200	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C1N71_06205	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C1N71_06215	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C1N71_06225	ENOG4105C03	ribonuclease
C1N71_06235	ENOG4105T0Z	Conserved Protein
C1N71_06240	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C1N71_06245	ENOG4105K46	50S ribosomal protein l27
C1N71_06250	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C1N71_06255	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C1N71_06265	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C1N71_06275	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C1N71_06290	ENOG4105ETE	Transcriptional regulator (LacI family
C1N71_06295	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
C1N71_06325	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C1N71_06335	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
C1N71_06345	ENOG4105CR4	methylisocitrate lyase
C1N71_06360	ENOG4105EW9	transcriptional regulator AsnC family
C1N71_06370	ENOG4105CPP	Dehydrogenase, E1 component
C1N71_06375	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C1N71_06380	ENOG4107QX3	carboxylase
C1N71_06400	ENOG4105C1G	acyl-Coa dehydrogenase
C1N71_06410	ENOG4105DFK	Polyphosphate glucokinase
C1N71_06455	ENOG4105KZX	Pterin carbinolamine dehydratase
C1N71_06470	ENOG4105DZC	cytosine deaminase
C1N71_06490	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C1N71_06495	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C1N71_06505	ENOG4105CAT	Cytidine monophosphate kinase
C1N71_06515	ENOG4105K56	Transcriptional regulator
C1N71_06530	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C1N71_06535	ENOG4107EUI	c reductase, iron-sulfur
C1N71_06540	ENOG4107UDY	cytochrome C
C1N71_06545	ENOG4105CCU	oxidase (Subunit III)
C1N71_06550	ENOG4107S1N	anthranilate phosphoribosyltransferase
C1N71_06560	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C1N71_06565	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C1N71_06570	ENOG4105CMT	Dihydroxyacetone kinase
C1N71_06575	ENOG4108UTZ	Dihydroxyacetone kinase
C1N71_06580	ENOG4105VDH	Dihydroxyacetone kinase
C1N71_06585	ENOG4105C57	major facilitator superfamily
C1N71_06605	ENOG4105D4Y	metalloprotease
C1N71_06640	ENOG41086D8	Transcriptional regulator
C1N71_06675	ENOG4105EWK	phytoene
C1N71_06730	ENOG4105VPX	protein, conserved in bacteria
C1N71_06770	ENOG4105E4C	Lytic transglycosylase catalytic
C1N71_06795	ENOG4105C3M	thioredoxin reductase
C1N71_06805	ENOG4105KTU	Transcriptional regulator, arsr family
C1N71_06865	ENOG4107JBM	CrcB-like protein
C1N71_06870	ENOG41083TI	Protein CrcB homolog
C1N71_06925	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C1N71_06930	ENOG4105C28	cystathionine
C1N71_06945	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C1N71_06960	ENOG4105DHQ	Histidine kinase
C1N71_06970	ENOG4105CSH	Transporter
C1N71_06975	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C1N71_06980	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C1N71_07000	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C1N71_07015	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C1N71_07030	ENOG4108FFZ	Transcriptional regulator
C1N71_07045	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
C1N71_07065	ENOG4105C8N	cysteinyl-tRNA synthetase
C1N71_07070	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C1N71_07075	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C1N71_07095	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C1N71_07105	ENOG41061WM	D-Alanyl-D-Alanine
C1N71_07120	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C1N71_07140	ENOG4105NRA	50s ribosomal protein l31 type b
C1N71_07145	ENOG4105DKW	ABC transporter
C1N71_07150	ENOG4107QPH	glycogen) synthase
C1N71_07155	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C1N71_07160	ENOG4105EAC	phosphoserine phosphatase
C1N71_07170	ENOG4105DKK	Benzoate
C1N71_07175	ENOG4105CHR	reductase
C1N71_07195	ENOG4105EN6	Membrane
C1N71_07200	ENOG4105C5H	ABC transporter
C1N71_07210	ENOG4105CJ1	ABC, transporter
C1N71_07225	ENOG4107ZYJ	bioY protein
C1N71_07245	ENOG41062B0	ABC transporter, permease
C1N71_07255	ENOG4105C2J	ABC transporter
C1N71_07260	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C1N71_07280	ENOG4105VG1	fes assembly suf system protein
C1N71_07285	ENOG4105C3K	feS assembly ATPase SufC
C1N71_07295	ENOG4105JRK	feS assembly protein SufD
C1N71_07300	ENOG4105DIW	FeS assembly protein SUFB
C1N71_07310	ENOG4107R33	ppx gppa phosphatase
C1N71_07315	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C1N71_07325	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C1N71_07330	ENOG4107QP8	phosphohexose isomerase
C1N71_07345	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
C1N71_07360	ENOG4105CP7	Triose-phosphate isomerase
C1N71_07365	ENOG4105BZA	Phosphoglycerate kinase
C1N71_07375	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C1N71_07380	ENOG4105CIE	May be required for sporulation (By similarity)
C1N71_07385	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C1N71_07390	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C1N71_07395	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C1N71_07400	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
C1N71_07405	ENOG4108JIK	carboxylase
C1N71_07410	ENOG4105P4J	Allophanate hydrolase, subunit 1
C1N71_07415	ENOG4105CFM	UPF0317 protein
C1N71_07420	ENOG4105E7W	lamb ycsf family protein
C1N71_07425	ENOG4105C5A	transporter
C1N71_07435	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C1N71_07445	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C1N71_07455	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C1N71_07480	ENOG4105KA0	thioesterase Superfamily protein
C1N71_07510	ENOG4105CBC	glutamate synthase
C1N71_07515	ENOG4107SYZ	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C1N71_07520	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C1N71_07525	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C1N71_07530	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C1N71_07550	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C1N71_07555	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C1N71_07560	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C1N71_07565	ENOG4105M0N	phosphoribosyl-ATP pyrophosphatase
C1N71_07580	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C1N71_07590	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C1N71_07600	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C1N71_07605	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C1N71_07610	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C1N71_07615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C1N71_07620	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C1N71_07630	ENOG4105CD3	dihydroorotase
C1N71_07635	ENOG4105CXT	aspartate transcarbamylase
C1N71_07640	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C1N71_07645	ENOG410803B	Involved in the transcription termination process (By similarity)
C1N71_07650	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C1N71_07655	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C1N71_07660	ENOG4105D49	3-dehydroquinate synthase
C1N71_07670	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C1N71_07675	ENOG4105E2X	shikimate dehydrogenase
C1N71_07680	ENOG4105HHA	aminodeoxychorismate lyase
C1N71_07685	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C1N71_07690	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C1N71_07700	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C1N71_07715	ENOG4105C99	atpase involved in dna repair
C1N71_07725	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C1N71_07730	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C1N71_07735	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C1N71_07745	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C1N71_07750	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C1N71_07755	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C1N71_07760	ENOG4105CDY	transcriptional regulatory protein
C1N71_07780	ENOG4105C22	threonyL-tRNA synthetase
C1N71_07830	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C1N71_07865	ENOG4105CHU	acetyl-coa acetyltransferase
C1N71_07870	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C1N71_07875	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C1N71_07900	ENOG4107QM5	aconitate hydratase
C1N71_07915	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
C1N71_07950	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C1N71_07965	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C1N71_07975	ENOG4105CDA	abc transporter atp-binding protein
C1N71_07980	ENOG4105DRP	amino acid AbC transporter
C1N71_07985	ENOG4105EAB	amino acid AbC transporter
C1N71_07990	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C1N71_08005	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C1N71_08030	ENOG4105C5F	glutamine synthetase
C1N71_08045	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C1N71_08060	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C1N71_08085	ENOG4105CJP	fad dependent oxidoreductase
C1N71_08090	ENOG4105E98	transcriptional regulator DeoR family
C1N71_08095	ENOG4105DE4	1-phosphofructokinase
C1N71_08100	ENOG4105DM4	PTS System
C1N71_08115	ENOG4105CVJ	phosphoglycerate mutase
C1N71_08125	ENOG4105EGD	dinuclear metal center protein, YbgI family
C1N71_08135	ENOG4105BZU	Histidine kinase
C1N71_08160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C1N71_08170	ENOG4105CSH	Transporter
C1N71_08185	ENOG4107XZQ	multidrug resistance protein
C1N71_08195	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C1N71_08210	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C1N71_08215	ENOG41082KT	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C1N71_08220	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C1N71_08250	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C1N71_08255	ENOG4105ENR	peptidase, M24
C1N71_08260	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C1N71_08265	ENOG4105CPF	Cell wall formation (By similarity)
C1N71_08275	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C1N71_08280	ENOG4105DWY	Agmatine deiminase
C1N71_08285	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
C1N71_08295	ENOG4105FF5	Membrane
C1N71_08310	ENOG4105DC8	reductase
C1N71_08320	ENOG4105CPK	Glycosyl transferase (Group 1
C1N71_08330	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C1N71_08340	ENOG4108JQ7	(ABC) transporter
C1N71_08345	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C1N71_08350	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C1N71_08360	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C1N71_08375	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C1N71_08380	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
C1N71_08385	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C1N71_08395	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1N71_08400	ENOG4105WH1	Two component transcriptional regulator luxr family
C1N71_08405	ENOG4105BZU	Histidine kinase
C1N71_08415	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C1N71_08425	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C1N71_08435	ENOG4107YU2	histidine triad (hIT) protein
C1N71_08445	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C1N71_08450	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C1N71_08470	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C1N71_08480	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C1N71_08485	ENOG4105TQK	DNA polymerase iii, delta' subunit
C1N71_08505	ENOG4105C8T	Leucyl-tRNA synthetase
C1N71_08530	ENOG4108JJ8	(ABC) transporter
C1N71_08545	ENOG4105EXC	Acyl-transferase
C1N71_08550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C1N71_08555	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C1N71_08565	ENOG4105E90	ABC transporter
C1N71_08570	ENOG4105E90	ABC transporter
C1N71_08575	ENOG4108IJ8	ABC transporter
C1N71_08580	ENOG4108SGK	Tetr family transcriptional regulator
C1N71_08585	ENOG4108RAV	Conserved protein
C1N71_08630	ENOG4108RNG	Permease of the drug metabolite transporter
C1N71_08635	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C1N71_08645	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C1N71_08660	ENOG4105FDF	Could be involved in DNA repair (By similarity)
C1N71_08680	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C1N71_08685	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C1N71_08690	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C1N71_08705	ENOG4107ZIW	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C1N71_08710	ENOG4107VQS	DivIVA family
C1N71_08720	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
C1N71_08730	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C1N71_08740	ENOG4105DFU	Cell wall formation (By similarity)
C1N71_08745	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C1N71_08755	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C1N71_08760	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C1N71_08770	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C1N71_08775	ENOG4105CJN	penicillin-binding protein
C1N71_08780	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C1N71_08785	ENOG4108V6E	Cell division protein mraZ
C1N71_08810	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
C1N71_08815	ENOG4105F6E	Acyl-transferase
C1N71_08825	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C1N71_08835	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C1N71_08840	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
C1N71_08855	ENOG4108UW8	fha domain-containing protein
C1N71_08870	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C1N71_08880	ENOG4105DEN	Luciferase family
C1N71_08885	ENOG4105CHU	acetyl-coa acetyltransferase
C1N71_08900	ENOG4107ZYR	domain protein
C1N71_08905	ENOG4105CZN	Potassium uptake protein
C1N71_08925	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C1N71_08935	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C1N71_08955	ENOG4105VEQ	Cold shock protein
C1N71_08960	ENOG4105C3M	thioredoxin reductase
C1N71_08975	ENOG4108SGK	Tetr family transcriptional regulator
C1N71_08995	ENOG4105E2T	synthase III
C1N71_09010	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
C1N71_09055	ENOG4105CEY	Amp-dependent synthetase and ligase
C1N71_09070	ENOG4105Q26	Siderophore-interacting protein
C1N71_09075	ENOG4105F27	Major Facilitator
C1N71_09080	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C1N71_09085	ENOG4108Q7D	Domain of unknown function (DUF2017)
C1N71_09125	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C1N71_09140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C1N71_09145	ENOG4105CAT	Cytidine monophosphate kinase
C1N71_09160	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C1N71_09165	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C1N71_09205	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C1N71_09210	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C1N71_09215	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C1N71_09240	ENOG4105DSU	hydrolase
C1N71_09270	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C1N71_09285	ENOG4105CH7	arginosuccinase
C1N71_09295	ENOG4105DBV	ornithine carbamoyltransferase
C1N71_09300	ENOG4105CAS	nag kinase
C1N71_09305	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C1N71_09310	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C1N71_09320	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C1N71_09325	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C1N71_09330	ENOG4105DRP	amino acid AbC transporter
C1N71_09335	ENOG4108Q1T	ABC transporter
C1N71_09345	ENOG4105CDA	abc transporter atp-binding protein
C1N71_09350	ENOG4108RWN	rrna methyltransferase
C1N71_09355	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C1N71_09360	ENOG41084BS	50S ribosomal protein L35
C1N71_09365	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C1N71_09380	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C1N71_09385	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C1N71_09390	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C1N71_09395	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C1N71_09405	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C1N71_09410	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C1N71_09415	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C1N71_09420	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C1N71_09425	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C1N71_09430	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C1N71_09450	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C1N71_09460	ENOG4105WBV	Transcriptional regulator
C1N71_09465	ENOG4105CEV	competence damage-inducible protein
C1N71_09475	ENOG4107QZI	cell division protein FtsK
C1N71_09480	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1N71_09485	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1N71_09495	ENOG4105CN5	Metallo-Beta-Lactamase
C1N71_09500	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C1N71_09510	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C1N71_09520	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C1N71_09535	ENOG4105C1V	Peptidase, M16
C1N71_09540	ENOG4108RVA	ribokinase
C1N71_09545	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C1N71_09555	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C1N71_09565	ENOG4108IJ0	Aspartate ammonia-lyase
C1N71_09580	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C1N71_09585	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C1N71_09605	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C1N71_09640	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C1N71_09645	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C1N71_09660	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C1N71_09690	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1N71_09695	ENOG4108HH4	Major Facilitator Superfamily
C1N71_09700	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C1N71_09710	ENOG4105DZP	Membrane-associated zinc metalloprotease
C1N71_09725	ENOG4108JPW	Aminotransferase
C1N71_09730	ENOG4105F76	Sarcosine oxidase
C1N71_09740	ENOG4105EC2	ftsk spoIIIe
C1N71_09755	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1N71_09770	ENOG4108ZF3	Phosphatase
C1N71_09780	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C1N71_09785	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C1N71_09795	ENOG4108FN7	Aldo keto reductase
C1N71_09800	ENOG4107XFJ	UPF0246 protein
C1N71_09805	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C1N71_09810	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C1N71_09815	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C1N71_09820	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C1N71_09825	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C1N71_09830	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
C1N71_09840	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
C1N71_09850	ENOG4105ESV	Glycosyl transferase, family 4
C1N71_09860	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C1N71_09870	ENOG4105D7W	serine acetyltransferase
C1N71_09895	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C1N71_09910	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
C1N71_09915	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C1N71_09935	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C1N71_09960	ENOG4105KPY	Small multidrug resistance protein
C1N71_09970	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C1N71_09980	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C1N71_09990	ENOG4105D6E	homoserine dehydrogenase
C1N71_10005	ENOG4105C75	arginyL-tRNA synthetase
C1N71_10035	ENOG4108VX5	3-methyladenine DNA glycosylase
C1N71_10045	ENOG4105CJP	fad dependent oxidoreductase
C1N71_10055	ENOG4105VPX	protein, conserved in bacteria
C1N71_10080	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C1N71_10110	ENOG41087YS	Phage shock protein A
C1N71_10115	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C1N71_10130	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
C1N71_10160	ENOG4105BZU	Histidine kinase
C1N71_10165	ENOG4105WH1	Two component transcriptional regulator luxr family
C1N71_10175	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C1N71_10185	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C1N71_10195	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
C1N71_10205	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
C1N71_10215	ENOG4107RNN	dihydropyrimidinase (EC 3.5.2.2)
C1N71_10235	ENOG4105EHG	Permease protein
C1N71_10240	ENOG4105E0A	ABC, transporter
C1N71_10260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1N71_10265	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
C1N71_10270	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C1N71_10275	ENOG4105CB5	ATP-dependent DNA helicase recG
C1N71_10280	ENOG4106H78	methyltransferase
C1N71_10300	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C1N71_10310	ENOG4105E5G	Alpha beta hydrolase fold
C1N71_10335	ENOG4105XEA	Tetr family transcriptional regulator
C1N71_10370	ENOG4105CSP	Major Facilitator Superfamily
C1N71_10405	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C1N71_10410	ENOG4105DJB	Major Facilitator Superfamily
C1N71_10420	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
C1N71_10430	ENOG4105CP7	Triose-phosphate isomerase
C1N71_10435	ENOG4107YVI	ribose 5-phosphate isomerase
C1N71_10440	ENOG4105CMT	Dihydroxyacetone kinase
C1N71_10445	ENOG4107RCW	fructose-bisphosphate aldolase
C1N71_10465	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C1N71_10470	ENOG4105CSH	Transporter
C1N71_10475	ENOG4105CWC	Acetylornithine deacetylase
C1N71_10480	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C1N71_10490	ENOG4105C9Q	fumarate hydratase class II
C1N71_10520	ENOG4105D22	carbon starvation protein
C1N71_10530	ENOG4108UMI	ABC transporter, permease
C1N71_10535	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C1N71_10540	ENOG4105D01	(LipO)protein
C1N71_10550	ENOG4108IAB	Phoh family
C1N71_10560	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C1N71_10580	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C1N71_10585	ENOG4105MS2	ribosomal subunit Interface protein
C1N71_10590	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C1N71_10595	ENOG4108T3R	lipoprotein lpqB
C1N71_10600	ENOG4105BZU	Histidine kinase
C1N71_10620	ENOG4105C5H	ABC transporter
C1N71_10630	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C1N71_10635	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C1N71_10640	ENOG4105F8V	Hydrolase, tatD family
C1N71_10665	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C1N71_10710	ENOG4105F8X	type iii restriction
C1N71_10725	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C1N71_10730	ENOG4105BZU	Histidine kinase
C1N71_10740	ENOG4105C5H	ABC transporter
C1N71_10765	ENOG4105CQ7	ATP-dependent helicase
C1N71_10770	ENOG4105EBR	Carboxylesterase
C1N71_10775	ENOG4105F2C	Acetyl-CoA acetyltransferase
C1N71_10790	ENOG4105CV8	reductase
C1N71_10810	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
C1N71_10825	ENOG4108KGH	TRANSCRIPTIONal
C1N71_10840	ENOG4105D3Q	Sugar transferase
C1N71_10875	ENOG4108QV3	biosynthesis protein
C1N71_10885	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C1N71_10915	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C1N71_10955	ENOG4105K4H	Nlp p60 protein
C1N71_10965	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C1N71_10975	ENOG4105VEQ	Cold shock protein
C1N71_10990	ENOG4105CFI	type iii restriction protein res subunit
C1N71_10995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C1N71_11000	ENOG4105BZU	Histidine kinase
C1N71_11010	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C1N71_11030	ENOG4105E0X	reductase
C1N71_11070	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C1N71_11075	ENOG4105C8N	cysteinyl-tRNA synthetase
C1N71_11080	ENOG4107RHR	regulatoR
C1N71_11090	ENOG4105K18	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
C1N71_11095	ENOG4105DT3	PTS system, galactitol-specific IIc component
C1N71_11105	ENOG4105CPP	Dehydrogenase, E1 component
C1N71_11110	ENOG4107RUY	(E1 component), alpha subunit
C1N71_11115	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
C1N71_11130	ENOG4105DZY	Pts system, glucitol sorbitol-specific
C1N71_11140	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C1N71_11145	ENOG4108VJ1	Transcriptional regulator (CarD family
C1N71_11160	ENOG4105BZU	Histidine kinase
C1N71_11170	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C1N71_11185	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C1N71_11190	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
C1N71_11200	ENOG4107NHD	transcriptional regulator
C1N71_11205	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C1N71_11210	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C1N71_11225	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C1N71_11295	ENOG4107WI4	Aldose-1-epimerase
C1N71_11305	ENOG4108Z0R	Transferase
C1N71_11310	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C1N71_11315	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C1N71_11325	ENOG4108XIC	integral membrane protein
C1N71_11335	ENOG4107RR1	TRANSCRIPTIONal
C1N71_11340	ENOG4105C26	Dehydrogenase
C1N71_11365	ENOG4105C26	Dehydrogenase
C1N71_11375	ENOG4105C0B	DNA polymerase III (alpha subunit)
C1N71_11385	ENOG4107EJG	GntR family transcriptional regulator
C1N71_11390	ENOG4105DG4	malate L-lactate dehydrogenase
C1N71_11395	ENOG4105F9U	Dehydrogenase
C1N71_11410	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C1N71_11435	ENOG4105CDH	Citrulline--aspartate ligase
C1N71_11440	ENOG4105CE4	GlcNAc 6-P deacetylase
C1N71_11445	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C1N71_11450	ENOG4105E2R	ROK family
C1N71_11455	ENOG4105D17	glycoside hydrolase, family 3 domain protein
C1N71_11465	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
C1N71_11485	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C1N71_11510	ENOG4105BZ1	(ABC) transporter
C1N71_11515	ENOG4105BZ1	(ABC) transporter
C1N71_11525	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C1N71_11540	ENOG4105E9K	Isocitrate dehydrogenase
C1N71_11560	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C1N71_11595	ENOG4105D8V	Glucose sorbosone dehydrogenase
C1N71_11600	ENOG4108MRH	transcriptional regulatory protein
C1N71_11605	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C1N71_11625	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C1N71_11635	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
C1N71_11665	ENOG4105CHP	RNA polymerase
C1N71_11675	ENOG4105C09	Bile acid
C1N71_11685	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C1N71_11710	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C1N71_11715	ENOG4107QVP	Dehydrogenase
C1N71_11735	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C1N71_11740	ENOG4105C32	Amino acid ABC transporter (Permease)
C1N71_11745	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
C1N71_11750	ENOG4105C0Z	ABC transporter
C1N71_11755	ENOG4108IV0	ABC, transporter
C1N71_11770	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C1N71_11790	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C1N71_11800	ENOG4108097	ATP-binding protein
C1N71_11810	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C1N71_11815	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C1N71_11820	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C1N71_11825	ENOG4105CS9	pantothenic acid kinase
C1N71_11840	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C1N71_11845	ENOG4108UJD	30S ribosomal protein S9
C1N71_11850	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C1N71_11870	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C1N71_11875	ENOG4108ZT0	50S ribosomal protein l17
C1N71_11880	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C1N71_11885	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C1N71_11890	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1N71_11900	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C1N71_11910	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C1N71_11915	ENOG4105CTS	PTS system mannitol-specific
C1N71_11930	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C1N71_11940	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C1N71_11945	ENOG410849U	50S ribosomal protein L30
C1N71_11950	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C1N71_11955	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C1N71_11960	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C1N71_11965	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C1N71_11970	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C1N71_11975	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C1N71_11980	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C1N71_11985	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C1N71_11990	ENOG41082SA	50s ribosomal protein l29
C1N71_11995	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C1N71_12000	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C1N71_12005	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C1N71_12010	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C1N71_12015	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1N71_12020	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C1N71_12025	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C1N71_12030	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C1N71_12035	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C1N71_12040	ENOG4108903	Formimidoylglutamase
C1N71_12045	ENOG4105CI2	imidazolone-5-propionate hydrolase
C1N71_12050	ENOG4105CGP	Urocanate hydratase
C1N71_12055	ENOG4105C84	Histidine ammonia-lyase
C1N71_12085	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C1N71_12090	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C1N71_12095	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C1N71_12100	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C1N71_12165	ENOG4105EC2	ftsk spoIIIe
C1N71_12175	ENOG4105D9P	serine threonine protein kinase
C1N71_12205	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1N71_12220	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C1N71_12225	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C1N71_12270	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C1N71_12275	ENOG4105F38	ABC transporter, permease
C1N71_12280	ENOG4105D38	putrescine abc transporter
C1N71_12325	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C1N71_12330	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
C1N71_12335	ENOG4105DRS	transport system, permease
C1N71_12350	ENOG41084IK	Phosphodiesterase
C1N71_12425	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C1N71_12435	ENOG4105DK7	lysyl-tRNA synthetase
C1N71_12455	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C1N71_12480	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1N71_12485	ENOG4105EEI	dihydropteroate synthase
C1N71_12490	ENOG4105EUJ	GTP cyclohydrolase i
C1N71_12495	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C1N71_12520	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C1N71_12525	ENOG4105F0N	pyrophosphate phospho-hydrolase
C1N71_12575	ENOG4105WH1	Two component transcriptional regulator luxr family
C1N71_12595	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C1N71_12610	ENOG410841Q	phosphoesterase PA-phosphatase related protein
C1N71_12615	ENOG4105CPN	adenine deaminase
C1N71_12625	ENOG4108594	Permease of the drug metabolite transporter
C1N71_12700	ENOG4105MJ9	esterase
C1N71_12715	ENOG4105EE5	Membrane protein terC
C1N71_12735	ENOG4105E5G	Alpha beta hydrolase fold
C1N71_12740	ENOG4105CSH	Transporter
C1N71_12745	ENOG4106N3A	copper homeostasis protein cutc
C1N71_12750	ENOG4105CSH	Transporter
C1N71_12780	ENOG4107SFI	Major Facilitator superfamily
C1N71_12785	ENOG4105C7K	acetolactate synthase
C1N71_12795	ENOG4105CHF	Glutathione S-transferase
C1N71_12810	ENOG4105CSH	Transporter
C1N71_12815	ENOG4105CSH	Transporter
C1N71_12825	ENOG4105DTD	Dehydrogenase
C1N71_12830	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C1N71_12850	ENOG4108PVQ	transcriptional regulator
C1N71_12870	ENOG4105CFC	Transporter
C1N71_12900	ENOG4105DRS	transport system, permease
C1N71_12905	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
C1N71_12920	ENOG4107QNK	)-transporter
C1N71_12925	ENOG4105K64	Glycosyl transferase, family 2
C1N71_12970	ENOG4108HQS	Glycine betaine
C1N71_12975	ENOG4108IJ7	Glycine betaine
C1N71_13000	ENOG4108JQ6	ABC transporter
C1N71_13010	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C1N71_13015	ENOG4105DEF	Extracellular solute-binding protein, family 5
C1N71_13020	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C1N71_13025	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C1N71_13030	ENOG4107HP6	Transcriptional regulator
C1N71_13035	ENOG4105FDP	GntR family transcriptional regulator
C1N71_13040	ENOG4108JQ1	Dehydrogenase
C1N71_13045	ENOG4108EMV	Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity)
C1N71_13050	ENOG41061GT	Aldolase
C1N71_13070	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
C1N71_13080	ENOG4105YB8	TM2 domain containing protein
C1N71_13095	ENOG4105EXW	epimerase dehydratase
C1N71_13100	ENOG41082JN	Transcriptional regulator
C1N71_13115	ENOG4105CBD	Diacylglycerol kinase
C1N71_13120	ENOG4105ETS	cytosine purines uracil thiamine allantoin
C1N71_13140	ENOG4108JCI	Transcriptional regulator
C1N71_13175	ENOG4105QPS	Monooxygenase
C1N71_13225	ENOG4105C4R	Atp-dependent dna helicase
C1N71_13250	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C1N71_13265	ENOG4108NIW	Leucine export protein LeuE
C1N71_13325	ENOG4105E5D	amino acid
C1N71_13330	ENOG4105CYP	glycoside hydrolase, family
C1N71_13335	ENOG4108X4Q	Hydrolase
C1N71_13375	ENOG41081K0	peptidylprolyl cis-trans isomerase
C1N71_13380	ENOG4105JXH	GntR family transcriptional regulator
C1N71_13385	ENOG4105ZXK	Dehydrogenase
C1N71_13390	ENOG4105CSH	Transporter
C1N71_13410	ENOG4105FDP	GntR family transcriptional regulator
C1N71_13415	ENOG4105CSH	Transporter
C1N71_13435	ENOG4105FDP	GntR family transcriptional regulator
C1N71_13440	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C1N71_13450	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
C1N71_13455	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C1N71_13475	ENOG4105DQ5	transport system permease protein
C1N71_13480	ENOG4108U1V	ABC transporter, permease
C1N71_13485	ENOG4105E0A	ABC, transporter
C1N71_13490	ENOG4105K4P	CoA-binding domain protein
C1N71_13575	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C1N71_13590	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
C1N71_13605	ENOG4106F60	Histidine kinase
C1N71_13620	ENOG4108UNV	SUF system FeS assembly protein, NifU family
C1N71_13645	ENOG4105CIK	Amidinotransferase
C1N71_13720	ENOG4105C87	Aminotransferase class I and II
C1N71_13755	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
C1N71_13780	ENOG4105DHP	deoxycytidine triphosphate deaminase
C1N71_13805	ENOG4108Z0Z	intracellular protease Pfpi family
C1N71_13810	ENOG4105CHU	acetyl-coa acetyltransferase
C1N71_13820	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C1N71_13825	ENOG4105DXM	phenylacetic acid degradation protein
C1N71_13870	ENOG4105CPQ	Dehydrogenase
C1N71_13875	ENOG4105CHR	reductase
C1N71_13885	ENOG4107YAU	phenylacetic acid degradation protein
C1N71_13890	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
C1N71_13895	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
C1N71_13900	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
C1N71_13905	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C1N71_13915	ENOG4105E9F	Enoyl-CoA hydratase
C1N71_13940	ENOG4105M6F	mutator MutT protein
C1N71_13975	ENOG4105MHT	Transcriptional regulator, ARSR family
C1N71_14005	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
C1N71_14010	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
C1N71_14015	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C1N71_14025	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C1N71_14050	ENOG4105BZW	Glycerate kinase
C1N71_14115	ENOG4105CEV	competence damage-inducible protein
C1N71_14120	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C1N71_14135	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C1N71_14170	ENOG4105EWK	phytoene
C1N71_14180	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C1N71_14185	ENOG4105CGD	Nad-dependent epimerase dehydratase
C1N71_14220	ENOG4107QUV	Domain protein
C1N71_14235	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
C1N71_14240	ENOG4105CVJ	phosphoglycerate mutase
C1N71_14250	ENOG4108426	dNA-binding protein
C1N71_14255	ENOG4108VW9	Membrane
C1N71_14280	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C1N71_14285	ENOG4105W0E	50S ribosomal protein L33
C1N71_14295	ENOG4105D7N	magnesium and cobalt transport protein CorA
C1N71_14335	ENOG4105K56	Transcriptional regulator
C1N71_14340	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C1N71_14365	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C1N71_14370	ENOG4105D9P	serine threonine protein kinase
C1N71_14380	ENOG4105CPC	Aldo Keto reductase
C1N71_14395	ENOG4107RN0	branched-chain alpha-keto acid dehydrogenase subunit E2
C1N71_14400	ENOG4105CPP	Dehydrogenase, E1 component
C1N71_14410	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C1N71_14415	ENOG41082T9	Membrane
C1N71_14420	ENOG4105CB2	alcohol dehydrogenase
C1N71_14435	ENOG4105KJF	protein tyrosine phosphatase
C1N71_14450	ENOG4107QTF	adenylosuccinate lyase
C1N71_14490	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C1N71_14495	ENOG4107TYH	extracellular solute-binding protein family 1
C1N71_14500	ENOG4105D81	ABC transporter, permease
C1N71_14505	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
C1N71_14515	ENOG4105KHC	sulfurtransferase
C1N71_14535	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
C1N71_14540	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
C1N71_14605	ENOG4105CH2	amidohydrolase
C1N71_14620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1N71_14655	ENOG4105CDU	Replicative dna helicase
C1N71_14665	ENOG4105EYF	MMPL domain protein
C1N71_14675	ENOG4105FDP	GntR family transcriptional regulator
C1N71_14680	ENOG4105CI1	PTS System
C1N71_14710	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C1N71_14715	ENOG4108V9W	transcriptional regulatory protein
C1N71_14725	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C1N71_14730	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C1N71_14735	ENOG4107YH6	single-stranded DNA-binding protein
C1N71_14740	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
C1N71_14745	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C1N71_14765	ENOG4105C3M	thioredoxin reductase
C1N71_14770	ENOG4105K63	Thioredoxin
C1N71_14780	ENOG4107QJE	Chromosome Partitioning Protein
C1N71_14790	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C1N71_14800	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C1N71_14805	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C1N71_14810	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C1N71_14815	ENOG41084CH	50S ribosomal protein l34