locus-tag	class	description
C1N71_00010	COG0592	DNA-directed DNA polymerase activity
C1N71_00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C1N71_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1N71_00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
C1N71_00035	COG0187	DNA topoisomerase II activity
C1N71_00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N71_00060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N71_00070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N71_00085	COG0494	nUDIX hydrolase
C1N71_00105	COG0705	Rhomboid family
C1N71_00125	COG0515	serine threonine protein kinase
C1N71_00130	COG0515	serine threonine protein kinase
C1N71_00135	COG0768	penicillin binding
C1N71_00170	COG1063	alcohol dehydrogenase
C1N71_00175	COG0477	Major facilitator Superfamily
C1N71_00180	COG1309	transcriptional regulator
C1N71_00200	COG0628	permease
C1N71_00215	COG2372	response to copper ion
C1N71_00215	COG1276	copper resistance
C1N71_00220	COG2847	Copper chaperone PCu(A)C
C1N71_00225	COG2837	iron assimilation
C1N71_00235	COG1960	acyl-CoA dehydrogenase activity
C1N71_00240	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_00265	COG0640	Transcriptional regulator
C1N71_00270	COG1609	Transcriptional regulator
C1N71_00280	COG0601	transmembrane transport
C1N71_00290	COG0444	Belongs to the ABC transporter superfamily
C1N71_00295	COG4608	Belongs to the ABC transporter superfamily
C1N71_00320	COG0671	phosphoesterase, PA-phosphatase related
C1N71_00365	COG0640	Transcriptional regulator
C1N71_00380	COG0698	ribose 5-phosphate isomerase
C1N71_00385	COG1609	Transcriptional regulator
C1N71_00410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1N71_00415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1N71_00430	COG4166	transmembrane transport
C1N71_00460	COG1902	pentaerythritol trinitrate reductase activity
C1N71_00495	COG0181	hydroxymethylbilane synthase activity
C1N71_00510	COG1846	Transcriptional regulator
C1N71_00525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C1N71_00540	COG1595	DNA-templated transcription, initiation
C1N71_00585	COG3237	CsbD-like
C1N71_00590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C1N71_00595	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_00610	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_00620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N71_00635	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_00675	COG0477	Major facilitator Superfamily
C1N71_00700	COG0477	Major facilitator Superfamily
C1N71_00710	COG0028	Belongs to the TPP enzyme family
C1N71_00715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N71_00730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1N71_00745	COG0395	ABC-type sugar transport system, permease component
C1N71_00750	COG1175	transmembrane transport
C1N71_00780	COG1113	amino acid transport
C1N71_00790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N71_00835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_00840	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_00860	COG2186	Transcriptional regulator
C1N71_00890	COG0861	Integral membrane protein TerC family
C1N71_00900	COG0753	catalase activity
C1N71_00920	COG0667	Aldo Keto reductase
C1N71_00940	COG0395	ABC-type sugar transport system, permease component
C1N71_00940	COG0395	ABC-type sugar transport system, permease component
C1N71_00945	COG1175	transmembrane transport
C1N71_00955	COG1653	transport
C1N71_00965	COG0366	Alpha amylase catalytic
C1N71_00975	COG2390	Transcriptional regulator
C1N71_00980	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_00990	COG1129	ABC transporter
C1N71_01000	COG1070	Carbohydrate kinase
C1N71_01005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1N71_01025	COG1741	Belongs to the pirin family
C1N71_01040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C1N71_01050	COG4821	SIS domain
C1N71_01055	COG2188	Transcriptional regulator
C1N71_01065	COG3340	Belongs to the peptidase S51 family
C1N71_01150	COG2814	Major facilitator Superfamily
C1N71_01170	COG0113	porphobilinogen synthase activity
C1N71_01175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C1N71_01185	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
C1N71_01190	COG0738	Major facilitator superfamily
C1N71_01200	COG1131	(ABC) transporter
C1N71_01205	COG3559	Exporter of polyketide antibiotics
C1N71_01210	COG0534	Mate efflux family protein
C1N71_01225	COG0477	Major facilitator Superfamily
C1N71_01235	COG1302	Protein conserved in bacteria
C1N71_01240	COG3590	peptidase
C1N71_01270	COG0824	Thioesterase
C1N71_01280	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_01295	COG1316	TRANSCRIPTIONal
C1N71_01300	COG2814	Major facilitator Superfamily
C1N71_01330	COG0443	Heat shock 70 kDa protein
C1N71_01335	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1N71_01340	COG0484	heat shock protein binding
C1N71_01345	COG0789	Transcriptional regulator
C1N71_01380	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N71_01380	COG2247	cell wall binding repeat
C1N71_01405	COG0542	response to heat
C1N71_01410	COG4702	Belongs to the UPF0303 family
C1N71_01435	COG2197	response regulator
C1N71_01440	COG1940	carbohydrate kinase activity
C1N71_01450	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C1N71_01470	COG0737	Belongs to the 5'-nucleotidase family
C1N71_01520	COG1668	transmembrane transport
C1N71_01525	COG4152	abc transporter atp-binding protein
C1N71_01530	COG2197	response regulator
C1N71_01535	COG4585	Histidine kinase
C1N71_01540	COG1702	phosphate starvation-inducible protein PhoH
C1N71_01570	COG0745	RESPONSE REGULATOR receiver
C1N71_01620	COG0803	Belongs to the bacterial solute-binding protein 9 family
C1N71_01630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1N71_01635	COG1120	ATPase activity
C1N71_01645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1N71_01675	COG2197	response regulator
C1N71_01685	COG0477	Major facilitator Superfamily
C1N71_01735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1N71_01745	COG1506	peptidase
C1N71_01745	COG0823	Involved in the tonB-independent uptake of proteins
C1N71_01750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1N71_01775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1N71_01800	COG0318	PFAM AMP-dependent synthetase and ligase
C1N71_01805	COG0047	phosphoribosylformylglycinamidine synthase activity
C1N71_01820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C1N71_01825	COG0151	Belongs to the GarS family
C1N71_01835	COG2233	PERMEase
C1N71_01850	COG4581	dead DEAH box helicase
C1N71_01865	COG1362	aminopeptidase activity
C1N71_01905	COG0235	Class ii aldolase
C1N71_01910	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_01915	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_01920	COG1129	ABC transporter
C1N71_01935	COG3254	rhamnose metabolic process
C1N71_01945	COG3347	Dehydrogenase
C1N71_01945	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_01950	COG1070	Carbohydrate kinase
C1N71_01960	COG0156	8-amino-7-oxononanoate synthase activity
C1N71_01965	COG1063	alcohol dehydrogenase
C1N71_01975	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1N71_01995	COG1760	l-serine dehydratase
C1N71_02015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N71_02020	COG0531	amino acid
C1N71_02025	COG0463	Glycosyl transferase, family 2
C1N71_02050	COG0789	Transcriptional regulator
C1N71_02055	COG1116	anion transmembrane transporter activity
C1N71_02065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N71_02070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N71_02075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1N71_02095	COG0514	ATP-dependent DNA helicase (RecQ)
C1N71_02110	COG2301	Belongs to the HpcH HpaI aldolase family
C1N71_02120	COG0477	Major facilitator Superfamily
C1N71_02130	COG1876	peptidase activity
C1N71_02155	COG0033	Phosphoglucomutase
C1N71_02170	COG3321	synthase
C1N71_02170	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_02170	COG0604	alcohol dehydrogenase
C1N71_02195	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C1N71_02205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C1N71_02210	COG0561	phosphatase activity
C1N71_02220	COG1316	TRANSCRIPTIONal
C1N71_02255	COG1024	Enoyl-CoA hydratase
C1N71_02260	COG1024	Enoyl-CoA hydratase
C1N71_02265	COG1278	Cold shock
C1N71_02300	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C1N71_02305	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_02310	COG2169	Transcriptional regulator
C1N71_02310	COG1917	Cupin 2, conserved barrel domain protein
C1N71_02315	COG1064	alcohol dehydrogenase
C1N71_02360	COG0686	Belongs to the AlaDH PNT family
C1N71_02370	COG1764	response to oxidative stress
C1N71_02375	COG0025	NhaP-type Na H and K H
C1N71_02395	COG1846	Transcriptional regulator
C1N71_02405	COG0277	FAD linked oxidase domain protein
C1N71_02410	COG0406	alpha-ribazole phosphatase activity
C1N71_02430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1N71_02435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N71_02440	COG3842	ATPase activity
C1N71_02445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N71_02450	COG1177	transmembrane transport
C1N71_02455	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N71_02470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C1N71_02485	COG2313	pseudouridylate synthase activity
C1N71_02530	COG0667	Aldo Keto reductase
C1N71_02540	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N71_02545	COG1201	RNA secondary structure unwinding
C1N71_02560	COG0745	RESPONSE REGULATOR receiver
C1N71_02565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1N71_02570	COG0590	tRNA wobble adenosine to inosine editing
C1N71_02600	COG3012	SEC-C Motif Domain Protein
C1N71_02605	COG0569	domain protein
C1N71_02610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N71_02635	COG0017	Asparaginyl-tRNA synthetase
C1N71_02675	COG0785	Cytochrome C biogenesis protein
C1N71_02680	COG1333	cytochrome c biogenesis protein
C1N71_02685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1N71_02690	COG4948	Mandelate Racemase Muconate Lactonizing
C1N71_02715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1N71_02740	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C1N71_02745	COG2326	polyphosphate kinase activity
C1N71_02760	COG2226	methyltransferase
C1N71_02795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1N71_02800	COG1666	GTP binding
C1N71_02810	COG0741	lytic transglycosylase activity
C1N71_02810	COG1196	nuclear chromosome segregation
C1N71_02810	COG0739	heme binding
C1N71_02815	COG0366	Alpha amylase catalytic
C1N71_02830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1N71_02835	COG1090	epimerase
C1N71_02850	COG2030	dehydratase
C1N71_02860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1N71_02870	COG0436	Aminotransferase
C1N71_02890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C1N71_02895	COG0081	regulation of translation
C1N71_02900	COG2197	response regulator
C1N71_02905	COG4585	Histidine kinase
C1N71_02930	COG0745	RESPONSE REGULATOR receiver
C1N71_02935	COG2205	protein histidine kinase activity
C1N71_02950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1N71_02955	COG0222	ribosome binding
C1N71_02965	COG3844	kynureninase activity
C1N71_02970	COG3046	protein related to deoxyribodipyrimidine photolyase
C1N71_02975	COG1132	(ABC) transporter
C1N71_02980	COG1940	carbohydrate kinase activity
C1N71_02980	COG1846	Transcriptional regulator
C1N71_02990	COG4214	carbohydrate transport
C1N71_03015	COG0477	Major facilitator Superfamily
C1N71_03020	COG0402	S-adenosylhomocysteine deaminase activity
C1N71_03025	COG2814	Major facilitator Superfamily
C1N71_03035	COG0433	COG0433 Predicted ATPase
C1N71_03060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1N71_03080	COG0667	Aldo Keto reductase
C1N71_03090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1N71_03095	COG0531	amino acid
C1N71_03110	COG0579	oxidoreductase
C1N71_03120	COG1435	thymidine kinase activity
C1N71_03135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1N71_03145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1N71_03210	COG0494	nUDIX hydrolase
C1N71_03245	COG1754	DNA topoisomerase type I activity
C1N71_03245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1N71_03250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1N71_03255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C1N71_03270	COG0747	negative chemotaxis
C1N71_03285	COG4172	Belongs to the ABC transporter superfamily
C1N71_03305	COG1335	isochorismatase
C1N71_03310	COG2409	Drug exporters of the RND superfamily
C1N71_03335	COG1132	(ABC) transporter
C1N71_03340	COG1131	(ABC) transporter
C1N71_03355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N71_03365	COG0477	Major facilitator Superfamily
C1N71_03375	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C1N71_03380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N71_03380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1N71_03395	COG0180	Tryptophanyl-tRNA synthetase
C1N71_03410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N71_03425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1N71_03440	COG2009	succinate dehydrogenase
C1N71_03450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C1N71_03455	COG0438	transferase activity, transferring glycosyl groups
C1N71_03465	COG1744	ABC transporter substrate-binding protein PnrA-like
C1N71_03510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1N71_03515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_03525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N71_03545	COG2205	protein histidine kinase activity
C1N71_03550	COG0745	RESPONSE REGULATOR receiver
C1N71_03575	COG4770	biotin carboxylase activity
C1N71_03595	COG2247	cell wall binding repeat
C1N71_03595	COG0860	N-Acetylmuramoyl-L-alanine amidase
C1N71_03600	COG0424	maF-like protein
C1N71_03610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N71_03630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N71_03645	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C1N71_03665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1N71_03700	COG2340	Cysteine-rich secretory protein family
C1N71_03715	COG1215	transferase activity, transferring glycosyl groups
C1N71_03770	COG0463	Glycosyl transferase, family 2
C1N71_03780	COG1960	acyl-CoA dehydrogenase activity
C1N71_03815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N71_03820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C1N71_03835	COG0861	Integral membrane protein TerC family
C1N71_03850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1N71_03855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1N71_03865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1N71_03875	COG1301	dicarboxylic acid transport
C1N71_03880	COG3290	protein histidine kinase activity
C1N71_03885	COG4565	transcriptional regulatory protein
C1N71_03890	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C1N71_03905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_03910	COG2084	Dehydrogenase
C1N71_03930	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_03940	COG1063	alcohol dehydrogenase
C1N71_03945	COG3265	gluconokinase activity
C1N71_03955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C1N71_03960	COG0193	aminoacyl-tRNA hydrolase activity
C1N71_03975	COG3956	TIGRFAM MazG family protein
C1N71_04010	COG0124	histidyl-tRNA synthetase
C1N71_04015	COG0148	phosphopyruvate hydratase activity
C1N71_04040	COG0477	Major facilitator Superfamily
C1N71_04070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1N71_04075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1N71_04085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N71_04140	COG0488	(ABC) transporter
C1N71_04185	COG1082	Xylose isomerase domain protein TIM barrel
C1N71_04190	COG0129	dihydroxy-acid dehydratase activity
C1N71_04200	COG0440	acetolactate synthase activity
C1N71_04205	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1N71_04210	COG1846	Transcriptional regulator
C1N71_04210	COG1940	carbohydrate kinase activity
C1N71_04225	COG1175	transmembrane transport
C1N71_04240	COG0673	inositol 2-dehydrogenase activity
C1N71_04285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N71_04300	COG0477	Major facilitator Superfamily
C1N71_04310	COG0473	3-isopropylmalate dehydrogenase activity
C1N71_04315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1N71_04320	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N71_04325	COG2855	membrane
C1N71_04330	COG2066	Belongs to the glutaminase family
C1N71_04340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1N71_04345	COG0492	ferredoxin-NADP+ reductase activity
C1N71_04365	COG4221	oxidoreductase activity
C1N71_04390	COG3971	2-oxopent-4-enoate hydratase activity
C1N71_04400	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_04410	COG0179	Fumarylacetoacetate (FAA) hydrolase
C1N71_04415	COG0477	Major facilitator Superfamily
C1N71_04420	COG0189	ligase activity
C1N71_04420	COG0569	domain protein
C1N71_04425	COG4067	protein conserved in archaea
C1N71_04425	COG0189	ligase activity
C1N71_04440	COG1492	cobalamin metabolic process
C1N71_04515	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C1N71_04520	COG0066	3-isopropylmalate dehydratase activity
C1N71_04525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C1N71_04545	COG1254	Belongs to the acylphosphatase family
C1N71_04575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1N71_04580	COG0012	GTP binding
C1N71_04590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1N71_04615	COG0702	epimerase
C1N71_04620	COG1733	regulation of RNA biosynthetic process
C1N71_04630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1N71_04635	COG0740	serine-type endopeptidase activity
C1N71_04640	COG0740	serine-type endopeptidase activity
C1N71_04650	COG2318	DinB family
C1N71_04665	COG2814	Major facilitator Superfamily
C1N71_04685	COG0386	Belongs to the glutathione peroxidase family
C1N71_04690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C1N71_04690	COG2111	Na H antiporter
C1N71_04715	COG1320	monovalent cation:proton antiporter activity
C1N71_04720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1N71_04725	COG0509	glycine decarboxylation via glycine cleavage system
C1N71_04730	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1N71_04730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1N71_04770	COG4172	Belongs to the ABC transporter superfamily
C1N71_04795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C1N71_04815	COG2252	PERMEase
C1N71_04835	COG2171	N-acyltransferase activity
C1N71_04840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_04855	COG4122	O-methyltransferase activity
C1N71_04865	COG2190	(PTS) system
C1N71_04865	COG2211	Major facilitator Superfamily
C1N71_04910	COG0006	proline dipeptidase activity
C1N71_04930	COG0277	FAD linked oxidase domain protein
C1N71_04935	COG0204	Acyl-transferase
C1N71_04935	COG0318	PFAM AMP-dependent synthetase and ligase
C1N71_04965	COG0613	PHP domain protein
C1N71_04975	COG0513	Belongs to the DEAD box helicase family
C1N71_05020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1N71_05025	COG1615	UPF0182 protein
C1N71_05050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N71_05065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C1N71_05095	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1N71_05100	COG1131	(ABC) transporter
C1N71_05125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C1N71_05130	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1N71_05135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1N71_05155	COG3537	Alpha-1,2-mannosidase
C1N71_05160	COG0586	Pfam SNARE associated Golgi protein
C1N71_05170	COG4221	oxidoreductase activity
C1N71_05180	COG2267	carboxylic ester hydrolase activity
C1N71_05185	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N71_05200	COG1121	(ABC) transporter
C1N71_05250	COG3425	synthase
C1N71_05280	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
C1N71_05290	COG2884	Cell division ATP-binding protein ftsE
C1N71_05295	COG2177	Part of the ABC transporter FtsEX involved in
C1N71_05300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C1N71_05320	COG0425	Belongs to the sulfur carrier protein TusA family
C1N71_05320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1N71_05330	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_05335	COG0483	inositol monophosphate 1-phosphatase activity
C1N71_05350	COG1162	GTPase activity
C1N71_05355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C1N71_05360	COG1595	DNA-templated transcription, initiation
C1N71_05375	COG0567	Dehydrogenase, E1 component
C1N71_05375	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_05410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C1N71_05420	COG3594	Acyltransferase
C1N71_05445	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C1N71_05450	COG0571	ribonuclease III activity
C1N71_05455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N71_05465	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_05500	COG2813	Specifically methylates the guanine in position
C1N71_05505	COG3739	integral membrane protein
C1N71_05545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_05550	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C1N71_05555	COG0228	four-way junction DNA binding
C1N71_05560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C1N71_05575	COG0335	large ribosomal subunit rRNA binding
C1N71_05585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C1N71_05605	COG0792	nuclease activity
C1N71_05610	COG0606	chelatase, subunit chli
C1N71_05635	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C1N71_05650	COG0052	Belongs to the universal ribosomal protein uS2 family
C1N71_05655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C1N71_05660	COG0528	UMP kinase activity
C1N71_05665	COG0233	cytoplasmic translational termination
C1N71_05690	COG0628	permease
C1N71_05700	COG3118	belongs to the thioredoxin family
C1N71_05710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1N71_05715	COG0366	Alpha amylase catalytic
C1N71_05735	COG0482	sulfurtransferase activity
C1N71_05740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C1N71_05750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1N71_05765	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1N71_05770	COG1733	regulation of RNA biosynthetic process
C1N71_05795	COG0154	amidase activity
C1N71_05800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C1N71_05815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_05840	COG4721	ABC-type cobalt transport system, permease component
C1N71_05845	COG1122	ATPase activity
C1N71_05885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C1N71_05900	COG0586	Pfam SNARE associated Golgi protein
C1N71_05915	COG0629	single-stranded DNA binding
C1N71_05945	COG1946	Acyl-CoA thioesterase
C1N71_05955	COG3573	Dehydrogenase
C1N71_05965	COG0668	transmembrane transport
C1N71_05975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C1N71_05980	COG0698	ribose 5-phosphate isomerase
C1N71_05995	COG2723	6-phospho-beta-galactosidase activity
C1N71_06020	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1N71_06020	COG0315	cyclic pyranopterin monophosphate synthase activity
C1N71_06035	COG0315	cyclic pyranopterin monophosphate synthase activity
C1N71_06070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1N71_06100	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1N71_06105	COG0740	serine-type endopeptidase activity
C1N71_06110	COG0740	serine-type endopeptidase activity
C1N71_06120	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C1N71_06125	COG1120	ATPase activity
C1N71_06155	COG4106	trans-aconitate 2-methyltransferase activity
C1N71_06165	COG0525	valine-tRNA ligase activity
C1N71_06180	COG0477	Major facilitator Superfamily
C1N71_06185	COG1309	transcriptional regulator
C1N71_06200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C1N71_06205	COG0285	dihydrofolate synthase activity
C1N71_06215	COG0105	UTP biosynthetic process
C1N71_06225	COG1530	ribonuclease E activity
C1N71_06235	COG3214	Protein conserved in bacteria
C1N71_06240	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1N71_06245	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C1N71_06250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C1N71_06255	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C1N71_06265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1N71_06275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1N71_06285	COG0799	negative regulation of ribosome biogenesis
C1N71_06290	COG1609	Transcriptional regulator
C1N71_06295	COG1175	transmembrane transport
C1N71_06325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N71_06335	COG2514	catechol 2,3-dioxygenase activity
C1N71_06345	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1N71_06360	COG1522	sequence-specific DNA binding
C1N71_06370	COG0022	dehydrogenase e1 component
C1N71_06375	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_06380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1N71_06400	COG1960	acyl-CoA dehydrogenase activity
C1N71_06410	COG1940	carbohydrate kinase activity
C1N71_06450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1N71_06455	COG2154	pterin-4-alpha-carbinolamine dehydratase
C1N71_06470	COG0402	S-adenosylhomocysteine deaminase activity
C1N71_06490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1N71_06495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1N71_06505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C1N71_06515	COG1846	Transcriptional regulator
C1N71_06530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1N71_06535	COG0723	plastoquinol--plastocyanin reductase activity
C1N71_06540	COG2010	Cytochrome c
C1N71_06545	COG1845	cytochrome c oxidase, subunit III
C1N71_06550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1N71_06560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C1N71_06565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1N71_06570	COG2376	Dihydroxyacetone kinase
C1N71_06575	COG1461	Dihydroxyacetone kinase
C1N71_06580	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C1N71_06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1N71_06580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_06585	COG0477	Major facilitator Superfamily
C1N71_06595	COG1794	racemase activity, acting on amino acids and derivatives
C1N71_06625	COG2217	Heavy metal translocating P-type atpase
C1N71_06640	COG2207	Transcriptional regulator
C1N71_06640	COG3708	Transcriptional regulator
C1N71_06730	COG1937	Protein conserved in bacteria
C1N71_06735	COG2217	Heavy metal translocating P-type atpase
C1N71_06755	COG2608	mercury ion transmembrane transporter activity
C1N71_06770	COG0739	heme binding
C1N71_06770	COG0741	lytic transglycosylase activity
C1N71_06770	COG1196	nuclear chromosome segregation
C1N71_06790	COG0798	PFAM Bile acid sodium symporter
C1N71_06805	COG0640	Transcriptional regulator
C1N71_06865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N71_06870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1N71_06930	COG0626	cystathionine gamma-synthase activity
C1N71_06945	COG1051	belongs to the nudix hydrolase family
C1N71_06970	COG0477	Major facilitator Superfamily
C1N71_06975	COG4946	Tricorn protease homolog
C1N71_06975	COG1506	peptidase
C1N71_06975	COG0823	Involved in the tonB-independent uptake of proteins
C1N71_06980	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_07000	COG1216	Glycosyl transferase, family 2
C1N71_07015	COG0805	protein transport
C1N71_07020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1N71_07030	COG2378	regulation of single-species biofilm formation
C1N71_07045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1N71_07065	COG0215	cysteine-tRNA ligase activity
C1N71_07070	COG1968	undecaprenyl-diphosphatase activity
C1N71_07075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_07095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1N71_07120	COG0438	transferase activity, transferring glycosyl groups
C1N71_07140	COG0254	rRNA binding
C1N71_07145	COG1119	ATPase activity
C1N71_07150	COG0297	glycogen (starch) synthase activity
C1N71_07155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1N71_07160	COG0560	Phosphoserine phosphatase
C1N71_07170	COG3135	benzoate transporter
C1N71_07175	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_07195	COG2860	membrane
C1N71_07200	COG0488	(ABC) transporter
C1N71_07210	COG1131	(ABC) transporter
C1N71_07225	COG1268	BioY protein
C1N71_07245	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_07250	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1N71_07255	COG1129	ABC transporter
C1N71_07260	COG1879	ABC-type sugar transport system periplasmic component
C1N71_07270	COG1609	Transcriptional regulator
C1N71_07280	COG2151	metal-sulfur cluster biosynthetic enzyme
C1N71_07285	COG0396	ATPase activity
C1N71_07295	COG0719	Fe-S assembly protein
C1N71_07300	COG0719	Fe-S assembly protein
C1N71_07310	COG0248	Ppx GppA phosphatase
C1N71_07315	COG0109	protoheme IX farnesyltransferase activity
C1N71_07325	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1N71_07330	COG0166	Belongs to the GPI family
C1N71_07345	COG0363	glucosamine-6-phosphate deaminase activity
C1N71_07355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1N71_07360	COG0149	triose-phosphate isomerase activity
C1N71_07365	COG0126	phosphoglycerate kinase activity
C1N71_07375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1N71_07380	COG1481	regulation of sporulation
C1N71_07385	COG1660	Displays ATPase and GTPase activities
C1N71_07390	COG0322	excinuclease ABC activity
C1N71_07400	COG0783	Belongs to the Dps family
C1N71_07405	COG4770	biotin carboxylase activity
C1N71_07410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C1N71_07415	COG4336	lyase activity
C1N71_07420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C1N71_07425	COG1914	H( )-stimulated, divalent metal cation uptake system
C1N71_07435	COG0556	nucleotide-excision repair
C1N71_07445	COG0237	dephospho-CoA kinase activity
C1N71_07455	COG0539	negative regulation of cytoplasmic translation
C1N71_07480	COG2050	protein possibly involved in aromatic compounds catabolism
C1N71_07510	COG0067	glutamate synthase
C1N71_07510	COG0070	glutamate synthase
C1N71_07510	COG0069	glutamate synthase activity
C1N71_07515	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C1N71_07520	COG0159	tryptophan synthase activity
C1N71_07525	COG0133	tryptophan synthase activity
C1N71_07530	COG0134	indole-3-glycerol-phosphate synthase activity
C1N71_07550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1N71_07555	COG0107	imidazoleglycerol-phosphate synthase activity
C1N71_07560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C1N71_07565	COG0140	phosphoribosyl-ATP diphosphatase activity
C1N71_07580	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1N71_07590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C1N71_07600	COG1758	RNA polymerase activity
C1N71_07605	COG0194	GDP metabolic process
C1N71_07610	COG0284	orotidine-5'-phosphate decarboxylase activity
C1N71_07615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1N71_07620	COG0505	Belongs to the CarA family
C1N71_07630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N71_07635	COG0540	Belongs to the ATCase OTCase family
C1N71_07640	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C1N71_07645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1N71_07650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C1N71_07655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1N71_07660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C1N71_07665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1N71_07670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C1N71_07675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C1N71_07680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1N71_07685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1N71_07690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1N71_07700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C1N71_07715	COG1196	nuclear chromosome segregation
C1N71_07725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1N71_07730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N71_07735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1N71_07745	COG2255	four-way junction helicase activity
C1N71_07750	COG0632	four-way junction helicase activity
C1N71_07755	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C1N71_07760	COG0217	transcriptional regulatory protein
C1N71_07780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C1N71_07830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1N71_07865	COG0183	Belongs to the thiolase family
C1N71_07870	COG1024	Enoyl-CoA hydratase
C1N71_07870	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N71_07900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C1N71_07915	COG0756	dUTP diphosphatase activity
C1N71_07950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C1N71_07965	COG0187	DNA topoisomerase II activity
C1N71_07975	COG1126	abc transporter atp-binding protein
C1N71_07980	COG0765	amino acid transport
C1N71_07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1N71_07990	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1N71_08005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1N71_08010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1N71_08015	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_08030	COG0174	glutamine synthetase
C1N71_08045	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1N71_08060	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C1N71_08085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_08090	COG1349	DNA-binding transcription factor activity
C1N71_08100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N71_08100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_08100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1N71_08115	COG0328	RNA-DNA hybrid ribonuclease activity
C1N71_08115	COG0406	alpha-ribazole phosphatase activity
C1N71_08125	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1N71_08135	COG5002	protein histidine kinase activity
C1N71_08170	COG0477	Major facilitator Superfamily
C1N71_08185	COG2814	Major facilitator Superfamily
C1N71_08195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1N71_08210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N71_08215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1N71_08220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1N71_08250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_08255	COG0006	proline dipeptidase activity
C1N71_08260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N71_08265	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1N71_08275	COG0154	amidase activity
C1N71_08280	COG2957	Belongs to the agmatine deiminase family
C1N71_08295	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C1N71_08320	COG0438	transferase activity, transferring glycosyl groups
C1N71_08330	COG0242	peptide deformylase activity
C1N71_08340	COG4608	Belongs to the ABC transporter superfamily
C1N71_08345	COG0358	DNA primase activity
C1N71_08350	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C1N71_08360	COG0423	glycine-tRNA ligase activity
C1N71_08375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N71_08380	COG1381	Involved in DNA repair and RecF pathway recombination
C1N71_08385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N71_08395	COG1136	(ABC) transporter
C1N71_08395	COG0577	efflux transmembrane transporter activity
C1N71_08400	COG2197	response regulator
C1N71_08405	COG4585	Histidine kinase
C1N71_08425	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C1N71_08435	COG0537	adenosine 5'-monophosphoramidase activity
C1N71_08445	COG0484	heat shock protein binding
C1N71_08450	COG1420	regulation of RNA biosynthetic process
C1N71_08470	COG0481	GTPase activity
C1N71_08480	COG0268	Binds directly to 16S ribosomal RNA
C1N71_08485	COG1466	dna polymerase III delta subunit
C1N71_08505	COG0495	leucyl-tRNA aminoacylation
C1N71_08515	COG0512	Glutamine amidotransferase of anthranilate synthase
C1N71_08515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1N71_08530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1N71_08545	COG2755	lipolytic protein G-D-S-L family
C1N71_08545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C1N71_08550	COG1294	oxidase, subunit
C1N71_08555	COG1271	oxidase subunit
C1N71_08565	COG1174	glycine betaine transport
C1N71_08570	COG1174	glycine betaine transport
C1N71_08575	COG1125	glycine betaine transport
C1N71_08575	COG0517	IMP dehydrogenase activity
C1N71_08580	COG1309	transcriptional regulator
C1N71_08585	COG2135	peptidase activity
C1N71_08630	COG0697	spore germination
C1N71_08635	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C1N71_08645	COG0477	Major facilitator Superfamily
C1N71_08660	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C1N71_08680	COG0167	dihydroorotate dehydrogenase activity
C1N71_08685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1N71_08690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1N71_08705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C1N71_08710	COG3599	regulation of cell shape
C1N71_08720	COG1799	cell septum assembly
C1N71_08730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1N71_08740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1N71_08745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C1N71_08755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C1N71_08760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N71_08770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1N71_08775	COG0768	penicillin binding
C1N71_08780	COG0275	rRNA processing
C1N71_08785	COG2001	Belongs to the MraZ family
C1N71_08810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
C1N71_08815	COG0204	Acyl-transferase
C1N71_08835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C1N71_08840	COG1192	Involved in chromosome partitioning
C1N71_08855	COG1716	ATPase activity
C1N71_08870	COG2818	Glycosylase
C1N71_08880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_08885	COG0183	Belongs to the thiolase family
C1N71_08900	COG0569	domain protein
C1N71_08905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1N71_08925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C1N71_08935	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C1N71_08955	COG1278	Cold shock
C1N71_08960	COG0492	ferredoxin-NADP+ reductase activity
C1N71_08975	COG1309	transcriptional regulator
C1N71_08995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1N71_09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1N71_09055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1N71_09070	COG2375	cellular response to nickel ion
C1N71_09075	COG2814	Major facilitator Superfamily
C1N71_09080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C1N71_09125	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C1N71_09140	COG1160	GTP binding
C1N71_09145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C1N71_09160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1N71_09165	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C1N71_09205	COG0504	CTP synthase activity
C1N71_09210	COG0497	DNA recombination
C1N71_09215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C1N71_09240	COG0647	UMP catabolic process
C1N71_09270	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1N71_09285	COG0165	Argininosuccinate lyase
C1N71_09295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1N71_09300	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1N71_09305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C1N71_09310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1N71_09320	COG0072	phenylalanine-tRNA ligase activity
C1N71_09320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N71_09325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C1N71_09330	COG0765	amino acid transport
C1N71_09335	COG0765	amino acid transport
C1N71_09345	COG1126	abc transporter atp-binding protein
C1N71_09350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1N71_09355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C1N71_09360	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C1N71_09365	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C1N71_09380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1N71_09385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1N71_09390	COG0131	Imidazoleglycerol-phosphate dehydratase
C1N71_09395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1N71_09405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1N71_09410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1N71_09420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C1N71_09425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C1N71_09430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1N71_09450	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1N71_09460	COG1396	sequence-specific DNA binding
C1N71_09465	COG1546	Belongs to the CinA family
C1N71_09465	COG1058	Belongs to the CinA family
C1N71_09475	COG1674	ftsk spoiiie
C1N71_09480	COG0577	efflux transmembrane transporter activity
C1N71_09480	COG1136	(ABC) transporter
C1N71_09485	COG0577	efflux transmembrane transporter activity
C1N71_09485	COG1136	(ABC) transporter
C1N71_09495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C1N71_09500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1N71_09510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C1N71_09520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C1N71_09535	COG0612	Peptidase, M16
C1N71_09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1N71_09545	COG1185	polyribonucleotide nucleotidyltransferase activity
C1N71_09555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1N71_09580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_09585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C1N71_09605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C1N71_09625	COG2311	Membrane
C1N71_09640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C1N71_09645	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C1N71_09645	COG3266	domain, Protein
C1N71_09660	COG0442	prolyl-tRNA aminoacylation
C1N71_09690	COG0714	Associated with various cellular activities
C1N71_09695	COG2814	Major facilitator Superfamily
C1N71_09700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C1N71_09710	COG0750	zinc metalloprotease
C1N71_09725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1N71_09730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_09755	COG0714	Associated with various cellular activities
C1N71_09770	COG0631	protein serine/threonine phosphatase activity
C1N71_09780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N71_09785	COG0405	Gamma-glutamyltransferase
C1N71_09795	COG0667	Aldo Keto reductase
C1N71_09800	COG3022	response to hydroperoxide
C1N71_09805	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1N71_09810	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C1N71_09815	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1N71_09820	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C1N71_09825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1N71_09830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C1N71_09840	COG0356	it plays a direct role in the translocation of protons across the membrane
C1N71_09850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1N71_09860	COG2890	protein-(glutamine-N5) methyltransferase activity
C1N71_09870	COG1045	serine acetyltransferase
C1N71_09895	COG0588	phosphoglycerate mutase activity
C1N71_09910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1N71_09915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1N71_09930	COG1178	ABC-type Fe3 transport system permease component
C1N71_09935	COG3842	ATPase activity
C1N71_09940	COG1840	ABC-type Fe3 transport system, periplasmic component
C1N71_09960	COG2076	Multidrug Resistance protein
C1N71_09970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C1N71_09980	COG0083	homoserine kinase activity
C1N71_09990	COG0460	homoserine dehydrogenase
C1N71_10005	COG0018	arginyl-trna synthetase
C1N71_10035	COG2094	Belongs to the DNA glycosylase MPG family
C1N71_10045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1N71_10055	COG1937	Protein conserved in bacteria
C1N71_10070	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_10080	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
C1N71_10110	COG1842	Phage shock protein A
C1N71_10115	COG0297	glycogen (starch) synthase activity
C1N71_10130	COG0346	lactoylglutathione lyase activity
C1N71_10150	COG1131	(ABC) transporter
C1N71_10160	COG4585	Histidine kinase
C1N71_10165	COG2197	response regulator
C1N71_10175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C1N71_10185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1N71_10195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N71_10205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1N71_10215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1N71_10235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N71_10240	COG1120	ATPase activity
C1N71_10260	COG0714	Associated with various cellular activities
C1N71_10265	COG0778	Nitroreductase
C1N71_10265	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
C1N71_10270	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C1N71_10275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1N71_10280	COG0742	ribosomal rna small subunit methyltransferase
C1N71_10300	COG2176	DNA-directed DNA polymerase activity
C1N71_10305	COG1322	Protein conserved in bacteria
C1N71_10310	COG2267	carboxylic ester hydrolase activity
C1N71_10330	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_10335	COG1309	transcriptional regulator
C1N71_10370	COG2271	Major facilitator Superfamily
C1N71_10375	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_10410	COG2271	Major facilitator Superfamily
C1N71_10420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C1N71_10430	COG0149	triose-phosphate isomerase activity
C1N71_10435	COG0698	ribose 5-phosphate isomerase
C1N71_10440	COG2376	Dihydroxyacetone kinase
C1N71_10445	COG0191	fructose-bisphosphate aldolase activity
C1N71_10465	COG1570	exodeoxyribonuclease VII activity
C1N71_10470	COG0477	Major facilitator Superfamily
C1N71_10475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_10480	COG1722	exodeoxyribonuclease VII activity
C1N71_10490	COG0114	fumarate hydratase activity
C1N71_10495	COG1505	serine-type exopeptidase activity
C1N71_10520	COG1966	Carbon starvation protein
C1N71_10530	COG2011	ABC-type metal ion transport system permease component
C1N71_10535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N71_10550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1N71_10560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1N71_10580	COG0653	protein targeting
C1N71_10590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1N71_10595	COG5401	PFAM Sporulation and spore germination
C1N71_10600	COG5002	protein histidine kinase activity
C1N71_10620	COG0488	(ABC) transporter
C1N71_10630	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C1N71_10635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C1N71_10640	COG0084	hydrolase, TatD family'
C1N71_10665	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1N71_10710	COG1061	Type III restriction enzyme res subunit
C1N71_10725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1N71_10730	COG4585	Histidine kinase
C1N71_10740	COG0488	(ABC) transporter
C1N71_10765	COG1643	Atp-dependent helicase
C1N71_10775	COG0183	Belongs to the thiolase family
C1N71_10790	COG0656	L-ascorbic acid biosynthetic process
C1N71_10810	COG3281	Trehalose synthase
C1N71_10825	COG1316	TRANSCRIPTIONal
C1N71_10830	COG1086	Polysaccharide biosynthesis protein
C1N71_10840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C1N71_10875	COG0489	protein tyrosine kinase activity
C1N71_10880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_10885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1N71_10915	COG1970	mechanosensitive ion channel activity
C1N71_10920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_10955	COG0791	NLP P60 protein
C1N71_10965	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1N71_10975	COG1278	Cold shock
C1N71_10990	COG1061	Type III restriction enzyme res subunit
C1N71_10995	COG0745	RESPONSE REGULATOR receiver
C1N71_11000	COG2205	protein histidine kinase activity
C1N71_11010	COG0459	protein refolding
C1N71_11030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1N71_11075	COG0215	cysteine-tRNA ligase activity
C1N71_11080	COG2390	Transcriptional regulator
C1N71_11090	COG3414	Phosphotransferase system galactitol-specific IIB component
C1N71_11095	COG3775	system Galactitol-specific IIC component
C1N71_11100	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_11105	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_11105	COG0022	dehydrogenase e1 component
C1N71_11110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C1N71_11115	COG0673	inositol 2-dehydrogenase activity
C1N71_11130	COG3732	PTS system glucitol sorbitol-specific
C1N71_11140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C1N71_11140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1N71_11145	COG1329	Transcriptional regulator
C1N71_11160	COG5002	protein histidine kinase activity
C1N71_11170	COG0588	phosphoglycerate mutase activity
C1N71_11185	COG0354	folic acid binding
C1N71_11190	COG4044	May play a role in the intracellular transport of hydrophobic ligands
C1N71_11200	COG0745	RESPONSE REGULATOR receiver
C1N71_11205	COG0454	-acetyltransferase
C1N71_11205	COG0456	acetyltransferase
C1N71_11210	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1N71_11225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1N71_11295	COG2017	converts alpha-aldose to the beta-anomer
C1N71_11310	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C1N71_11315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1N71_11340	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_11365	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_11375	COG0587	DNA-directed DNA polymerase activity
C1N71_11385	COG2186	Transcriptional regulator
C1N71_11390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C1N71_11395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N71_11420	COG1640	4-alpha-glucanotransferase
C1N71_11435	COG0137	argininosuccinate synthase activity
C1N71_11440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1N71_11445	COG0363	glucosamine-6-phosphate deaminase activity
C1N71_11450	COG1940	carbohydrate kinase activity
C1N71_11450	COG1846	Transcriptional regulator
C1N71_11455	COG1472	Belongs to the glycosyl hydrolase 3 family
C1N71_11465	COG1175	transmembrane transport
C1N71_11485	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C1N71_11495	COG1737	Transcriptional regulator
C1N71_11510	COG1132	(ABC) transporter
C1N71_11515	COG1132	(ABC) transporter
C1N71_11525	COG0138	bifunctional purine biosynthesis protein purh
C1N71_11540	COG2838	Isocitrate dehydrogenase
C1N71_11560	COG0045	succinate-CoA ligase (ADP-forming) activity
C1N71_11605	COG3290	protein histidine kinase activity
C1N71_11625	COG0259	pyridoxamine-phosphate oxidase activity
C1N71_11635	COG0584	glycerophosphoryl diester phosphodiesterase
C1N71_11665	COG4941	Belongs to the sigma-70 factor family
C1N71_11675	COG0385	Bile acid
C1N71_11685	COG0519	Catalyzes the synthesis of GMP from XMP
C1N71_11685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1N71_11710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1N71_11715	COG0516	GMP reductase activity
C1N71_11770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1N71_11790	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1N71_11800	COG0802	atpase or kinase
C1N71_11810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1N71_11815	COG0736	holo-[acyl-carrier-protein] synthase activity
C1N71_11820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1N71_11825	COG1072	(Pantothenic acid kinase))
C1N71_11840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1N71_11845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C1N71_11850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C1N71_11870	COG0101	tRNA pseudouridine synthase activity
C1N71_11875	COG0203	ribosomal protein L17
C1N71_11880	COG0202	RNA polymerase activity
C1N71_11885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1N71_11890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1N71_11900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1N71_11910	COG0246	Mannitol dehydrogenase
C1N71_11915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1N71_11915	COG2213	PTS system mannitol-specific
C1N71_11930	COG0563	adenylate kinase activity
C1N71_11940	COG0200	Binds to the 23S rRNA
C1N71_11945	COG1841	ribosomal large subunit assembly
C1N71_11950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C1N71_11955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C1N71_11960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C1N71_11965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C1N71_11970	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C1N71_11975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C1N71_11980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C1N71_11985	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C1N71_11990	COG0255	Belongs to the universal ribosomal protein uL29 family
C1N71_11995	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C1N71_12000	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C1N71_12005	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C1N71_12010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C1N71_12015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1N71_12020	COG0089	rRNA binding
C1N71_12025	COG0088	Forms part of the polypeptide exit tunnel
C1N71_12030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C1N71_12035	COG0051	transcription antitermination factor activity, RNA binding
C1N71_12040	COG0010	Belongs to the arginase family
C1N71_12045	COG1228	amidohydrolase
C1N71_12050	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1N71_12055	COG2986	histidine ammonia-lyase
C1N71_12085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C1N71_12090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1N71_12095	COG0049	tRNA binding
C1N71_12100	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C1N71_12165	COG1674	ftsk spoiiie
C1N71_12175	COG0515	serine threonine protein kinase
C1N71_12175	COG2815	serine threonine protein kinase
C1N71_12205	COG0714	Associated with various cellular activities
C1N71_12220	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C1N71_12225	COG0085	RNA polymerase activity
C1N71_12270	COG3842	ATPase activity
C1N71_12275	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N71_12280	COG1177	transmembrane transport
C1N71_12325	COG0456	acetyltransferase
C1N71_12330	COG1175	transmembrane transport
C1N71_12335	COG0395	ABC-type sugar transport system, permease component
C1N71_12350	COG0622	Phosphoesterase
C1N71_12395	COG0454	-acetyltransferase
C1N71_12420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1N71_12425	COG0542	response to heat
C1N71_12435	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C1N71_12455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C1N71_12485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1N71_12490	COG0302	gtp cyclohydrolase
C1N71_12495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N71_12520	COG0037	tRNA processing
C1N71_12525	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1N71_12575	COG2197	response regulator
C1N71_12595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C1N71_12610	COG0671	phosphoesterase, PA-phosphatase related
C1N71_12615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C1N71_12635	COG4977	sequence-specific DNA binding
C1N71_12700	COG3545	Serine hydrolase
C1N71_12715	COG1253	flavin adenine dinucleotide binding
C1N71_12735	COG2267	carboxylic ester hydrolase activity
C1N71_12740	COG0477	Major facilitator Superfamily
C1N71_12745	COG3142	Participates in the control of copper homeostasis
C1N71_12750	COG0477	Major facilitator Superfamily
C1N71_12780	COG2814	Major facilitator Superfamily
C1N71_12785	COG0028	Belongs to the TPP enzyme family
C1N71_12795	COG0435	Glutathione S-transferase
C1N71_12810	COG0477	Major facilitator Superfamily
C1N71_12825	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_12850	COG1802	Transcriptional regulator
C1N71_12870	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C1N71_12900	COG0395	ABC-type sugar transport system, permease component
C1N71_12920	COG2814	Major facilitator Superfamily
C1N71_12925	COG0463	Glycosyl transferase, family 2
C1N71_12970	COG4176	ABC-type proline glycine betaine transport system permease component
C1N71_12975	COG4175	Glycine betaine
C1N71_12975	COG0517	IMP dehydrogenase activity
C1N71_13000	COG4172	Belongs to the ABC transporter superfamily
C1N71_13010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1N71_13015	COG0747	negative chemotaxis
C1N71_13025	COG0601	transmembrane transport
C1N71_13030	COG1414	Transcriptional regulator
C1N71_13035	COG2188	Transcriptional regulator
C1N71_13040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1N71_13045	COG1070	Carbohydrate kinase
C1N71_13065	COG1175	transmembrane transport
C1N71_13070	COG0395	ABC-type sugar transport system, permease component
C1N71_13080	COG2314	TM2 domain
C1N71_13095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1N71_13100	COG1309	transcriptional regulator
C1N71_13115	COG1597	lipid kinase activity
C1N71_13120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C1N71_13125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1N71_13140	COG1396	sequence-specific DNA binding
C1N71_13225	COG0210	DNA helicase
C1N71_13250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C1N71_13325	COG0531	amino acid
C1N71_13335	COG0561	phosphatase activity
C1N71_13360	COG0730	response to heat
C1N71_13375	COG0545	Peptidyl-prolyl cis-trans isomerase
C1N71_13380	COG2186	Transcriptional regulator
C1N71_13385	COG2084	Dehydrogenase
C1N71_13390	COG0477	Major facilitator Superfamily
C1N71_13395	COG3959	Transketolase, thiamine diphosphate binding domain
C1N71_13400	COG3958	Transketolase
C1N71_13410	COG2188	Transcriptional regulator
C1N71_13415	COG0477	Major facilitator Superfamily
C1N71_13425	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_13435	COG2188	Transcriptional regulator
C1N71_13440	COG2084	Dehydrogenase
C1N71_13450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C1N71_13455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C1N71_13475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N71_13480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1N71_13485	COG1120	ATPase activity
C1N71_13490	COG1832	CoA-binding protein
C1N71_13545	COG1305	Transglutaminase-like
C1N71_13575	COG0655	NAD(P)H dehydrogenase (quinone) activity
C1N71_13590	COG1082	Xylose isomerase domain protein TIM barrel
C1N71_13605	COG2205	protein histidine kinase activity
C1N71_13620	COG0822	iron-sulfur transferase activity
C1N71_13645	COG1834	amidinotransferase
C1N71_13720	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1N71_13755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1N71_13780	COG0717	Belongs to the dCTP deaminase family
C1N71_13805	COG0693	protein deglycase activity
C1N71_13820	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1N71_13825	COG2030	dehydratase
C1N71_13825	COG1012	belongs to the aldehyde dehydrogenase family
C1N71_13870	COG1063	alcohol dehydrogenase
C1N71_13885	COG2050	protein possibly involved in aromatic compounds catabolism
C1N71_13890	COG3396	Phenylacetate-CoA oxygenase
C1N71_13895	COG3460	Phenylacetate-CoA oxygenase
C1N71_13900	COG2151	metal-sulfur cluster biosynthetic enzyme
C1N71_13905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1N71_13915	COG1024	Enoyl-CoA hydratase
C1N71_13935	COG0542	response to heat
C1N71_13940	COG0494	nUDIX hydrolase
C1N71_13975	COG0640	Transcriptional regulator
C1N71_14010	COG1780	Probably involved in ribonucleotide reductase function
C1N71_14015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1N71_14025	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_14040	COG0604	alcohol dehydrogenase
C1N71_14040	COG3321	synthase
C1N71_14040	COG1028	Short-chain dehydrogenase reductase Sdr
C1N71_14050	COG1929	Belongs to the glycerate kinase type-1 family
C1N71_14115	COG1058	Belongs to the CinA family
C1N71_14115	COG1546	Belongs to the CinA family
C1N71_14120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C1N71_14135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1N71_14180	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1N71_14185	COG0702	epimerase
C1N71_14220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1N71_14235	COG1309	transcriptional regulator
C1N71_14240	COG0406	alpha-ribazole phosphatase activity
C1N71_14250	COG0776	regulation of translation
C1N71_14255	COG2364	Membrane
C1N71_14260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1N71_14280	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C1N71_14285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1N71_14290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C1N71_14295	COG0598	Magnesium transport protein CorA
C1N71_14325	COG1121	(ABC) transporter
C1N71_14335	COG1846	Transcriptional regulator
C1N71_14340	COG1764	response to oxidative stress
C1N71_14365	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1N71_14365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1N71_14370	COG2815	serine threonine protein kinase
C1N71_14370	COG0515	serine threonine protein kinase
C1N71_14380	COG0667	Aldo Keto reductase
C1N71_14395	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1N71_14400	COG0022	dehydrogenase e1 component
C1N71_14410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1N71_14415	COG1950	PFAM Membrane protein of
C1N71_14420	COG0604	alcohol dehydrogenase
C1N71_14435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1N71_14450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1N71_14490	COG3842	ATPase activity
C1N71_14495	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1N71_14500	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1N71_14505	COG1177	transmembrane transport
C1N71_14515	COG2897	thiosulfate sulfurtransferase activity
C1N71_14535	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C1N71_14540	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C1N71_14570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1N71_14620	COG1136	(ABC) transporter
C1N71_14620	COG0577	efflux transmembrane transporter activity
C1N71_14655	COG0305	Participates in initiation and elongation during chromosome replication
C1N71_14665	COG2409	Drug exporters of the RND superfamily
C1N71_14675	COG2188	Transcriptional regulator
C1N71_14680	COG1263	PTS System
C1N71_14680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1N71_14680	COG2190	(PTS) system
C1N71_14710	COG3290	protein histidine kinase activity
C1N71_14715	COG4565	transcriptional regulatory protein
C1N71_14725	COG0359	binds to the 23S rRNA
C1N71_14730	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C1N71_14735	COG0629	single-stranded DNA binding
C1N71_14740	COG0360	Binds together with S18 to 16S ribosomal RNA
C1N71_14745	COG0617	tRNA 3'-terminal CCA addition
C1N71_14780	COG1192	Involved in chromosome partitioning
C1N71_14790	COG0357	Ribosomal RNA small subunit methyltransferase G
C1N71_14800	COG0706	membrane insertase activity
C1N71_14805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C1N71_14810	COG0594	ribonuclease P activity
C1N71_14815	COG0230	Belongs to the bacterial ribosomal protein bL34 family