locus-tag	class	description
G127AT_00050	COG2378	regulation of single-species biofilm formation
G127AT_00065	COG1695	Transcriptional regulator
G127AT_00095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G127AT_00105	COG0508	dehydrogenase complex catalyzes the overall conversion of
G127AT_00130	COG1472	Belongs to the glycosyl hydrolase 3 family
G127AT_00135	COG2353	YceI-like domain
G127AT_00145	COG0488	(ABC) transporter
G127AT_00165	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_00170	COG0560	Phosphoserine phosphatase
G127AT_00175	COG1119	ATPase activity
G127AT_00180	COG0254	rRNA binding
G127AT_00225	COG0477	Major facilitator Superfamily
G127AT_00230	COG0626	cystathionine gamma-synthase activity
G127AT_00255	COG0587	DNA-directed DNA polymerase activity
G127AT_00280	COG3177	Filamentation induced by cAMP protein fic
G127AT_00285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G127AT_00295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G127AT_00300	COG1968	undecaprenyl-diphosphatase activity
G127AT_00310	COG0560	Phosphoserine phosphatase
G127AT_00335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G127AT_00340	COG0805	protein transport
G127AT_00360	COG0584	glycerophosphoryl diester phosphodiesterase
G127AT_00375	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_00385	COG1742	UPF0060 membrane protein
G127AT_00400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G127AT_00405	COG1247	-acetyltransferase
G127AT_00415	COG1051	belongs to the nudix hydrolase family
G127AT_00420	COG1131	(ABC) transporter
G127AT_00425	COG3559	Exporter of polyketide antibiotics
G127AT_00440	COG0346	lactoylglutathione lyase activity
G127AT_00445	COG1403	HNH endonuclease
G127AT_00450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G127AT_00455	COG0494	nUDIX hydrolase
G127AT_00465	COG0425	Belongs to the sulfur carrier protein TusA family
G127AT_00470	COG2391	methyltransferase activity
G127AT_00485	COG1461	Dihydroxyacetone kinase
G127AT_00490	COG2376	Dihydroxyacetone kinase
G127AT_00495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G127AT_00500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G127AT_00505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G127AT_00510	COG1845	cytochrome c oxidase, subunit III
G127AT_00515	COG2010	Cytochrome c
G127AT_00520	COG0723	plastoquinol--plastocyanin reductase activity
G127AT_00525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G127AT_00530	COG2226	methyltransferase
G127AT_00540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G127AT_00545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G127AT_00555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G127AT_00570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G127AT_00575	COG0187	DNA topoisomerase II activity
G127AT_00595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G127AT_00605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G127AT_00610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G127AT_00615	COG0508	dehydrogenase complex catalyzes the overall conversion of
G127AT_00635	COG0174	glutamine synthetase
G127AT_00640	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G127AT_00645	COG0174	glutamine synthetase
G127AT_00650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G127AT_00680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G127AT_00700	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G127AT_00710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G127AT_00715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G127AT_00720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G127AT_00740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G127AT_00740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G127AT_00755	COG0477	Major facilitator Superfamily
G127AT_00775	COG1204	response to ionizing radiation
G127AT_00795	COG0438	transferase activity, transferring glycosyl groups
G127AT_00810	COG2375	cellular response to nickel ion
G127AT_00825	COG4608	Belongs to the ABC transporter superfamily
G127AT_00840	COG0601	transmembrane transport
G127AT_00850	COG0358	DNA primase activity
G127AT_00855	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G127AT_00875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G127AT_00875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G127AT_00890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G127AT_00895	COG1381	Involved in DNA repair and RecF pathway recombination
G127AT_00900	COG2860	membrane
G127AT_00905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G127AT_00915	COG0577	efflux transmembrane transporter activity
G127AT_00915	COG1136	(ABC) transporter
G127AT_00920	COG1136	(ABC) transporter
G127AT_00920	COG0577	efflux transmembrane transporter activity
G127AT_00925	COG2197	response regulator
G127AT_00930	COG4585	Histidine kinase
G127AT_00935	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G127AT_00945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G127AT_00955	COG0537	adenosine 5'-monophosphoramidase activity
G127AT_00970	COG1420	regulation of RNA biosynthetic process
G127AT_00990	COG4762	Protein conserved in bacteria
G127AT_00995	COG0481	GTPase activity
G127AT_01000	COG4585	Histidine kinase
G127AT_01005	COG2197	response regulator
G127AT_01010	COG0596	Alpha beta hydrolase
G127AT_01015	COG0268	Binds directly to 16S ribosomal RNA
G127AT_01030	COG1596	polysaccharide export
G127AT_01030	COG1555	photosystem II stabilization
G127AT_01035	COG0495	leucyl-tRNA aminoacylation
G127AT_01040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G127AT_01040	COG0512	Glutamine amidotransferase of anthranilate synthase
G127AT_01045	COG1132	(ABC) transporter
G127AT_01050	COG4988	ABC transporter
G127AT_01055	COG1294	oxidase, subunit
G127AT_01060	COG1271	oxidase subunit
G127AT_01080	COG1732	Glycine betaine
G127AT_01090	COG1174	glycine betaine transport
G127AT_01115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G127AT_01120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G127AT_01125	COG0587	DNA-directed DNA polymerase activity
G127AT_01135	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G127AT_01150	COG1799	cell septum assembly
G127AT_01160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G127AT_01170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G127AT_01175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G127AT_01185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G127AT_01190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G127AT_01200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G127AT_01205	COG0768	penicillin binding
G127AT_01215	COG0275	rRNA processing
G127AT_01220	COG2001	Belongs to the MraZ family
G127AT_01230	COG0142	geranyltranstransferase activity
G127AT_01245	COG2815	serine threonine protein kinase
G127AT_01245	COG0515	serine threonine protein kinase
G127AT_01250	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G127AT_01260	COG1940	carbohydrate kinase activity
G127AT_01285	COG1192	Involved in chromosome partitioning
G127AT_01330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G127AT_01340	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G127AT_01345	COG2357	RelA SpoT domain protein
G127AT_01360	COG0542	response to heat
G127AT_01380	COG0586	Pfam SNARE associated Golgi protein
G127AT_01410	COG4592	Periplasmic binding protein
G127AT_01415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G127AT_01420	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G127AT_01425	COG1120	ATPase activity
G127AT_01435	COG1119	ATPase activity
G127AT_01455	COG4213	ABC transporter substrate-binding protein
G127AT_01460	COG1129	ABC transporter
G127AT_01465	COG4214	carbohydrate transport
G127AT_01515	COG4942	peptidase
G127AT_01525	COG0667	Aldo Keto reductase
G127AT_01535	COG0028	Belongs to the TPP enzyme family
G127AT_01540	COG0477	Major facilitator Superfamily
G127AT_01550	COG1349	DNA-binding transcription factor activity
G127AT_01555	COG0149	triose-phosphate isomerase activity
G127AT_01560	COG0698	ribose 5-phosphate isomerase
G127AT_01565	COG2376	Dihydroxyacetone kinase
G127AT_01575	COG1172	Belongs to the binding-protein-dependent transport system permease family
G127AT_01580	COG1129	ABC transporter
G127AT_01600	COG1872	DUF167
G127AT_01605	COG1160	GTP binding
G127AT_01610	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G127AT_01625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G127AT_01630	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G127AT_01645	COG0494	nUDIX hydrolase
G127AT_01650	COG0504	CTP synthase activity
G127AT_01655	COG0497	DNA recombination
G127AT_01660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G127AT_01675	COG1011	Hydrolase
G127AT_01705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G127AT_01720	COG2094	Belongs to the DNA glycosylase MPG family
G127AT_01725	COG0165	Argininosuccinate lyase
G127AT_01730	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G127AT_01735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G127AT_01740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G127AT_01745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G127AT_01750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G127AT_01760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G127AT_01760	COG0072	phenylalanine-tRNA ligase activity
G127AT_01765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G127AT_01775	COG0765	amino acid transport
G127AT_01780	COG0765	amino acid transport
G127AT_01785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G127AT_01790	COG1126	abc transporter atp-binding protein
G127AT_01795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G127AT_01800	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G127AT_01805	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G127AT_01810	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G127AT_01820	COG1201	RNA secondary structure unwinding
G127AT_01830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G127AT_01835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G127AT_01840	COG0131	Imidazoleglycerol-phosphate dehydratase
G127AT_01845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G127AT_01855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G127AT_01860	COG2267	carboxylic ester hydrolase activity
G127AT_01870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G127AT_01875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G127AT_01880	COG2813	Specifically methylates the guanine in position
G127AT_01885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G127AT_01890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G127AT_01895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G127AT_01905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G127AT_01920	COG1546	Belongs to the CinA family
G127AT_01920	COG1058	Belongs to the CinA family
G127AT_01930	COG1674	ftsk spoiiie
G127AT_01935	COG0577	efflux transmembrane transporter activity
G127AT_01940	COG1136	(ABC) transporter
G127AT_01940	COG0577	efflux transmembrane transporter activity
G127AT_01950	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G127AT_01955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G127AT_01960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G127AT_01980	COG1764	response to oxidative stress
G127AT_01985	COG1090	epimerase
G127AT_01995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G127AT_02015	COG0667	Aldo Keto reductase
G127AT_02025	COG2030	dehydratase
G127AT_02030	COG1960	acyl-CoA dehydrogenase activity
G127AT_02040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G127AT_02055	COG0508	dehydrogenase complex catalyzes the overall conversion of
G127AT_02060	COG0022	dehydrogenase e1 component
G127AT_02085	COG1185	polyribonucleotide nucleotidyltransferase activity
G127AT_02100	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_02125	COG1215	transferase activity, transferring glycosyl groups
G127AT_02145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G127AT_02170	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G127AT_02190	COG3189	MarR family transcriptional regulator
G127AT_02205	COG0545	Peptidyl-prolyl cis-trans isomerase
G127AT_02215	COG0277	FAD linked oxidase domain protein
G127AT_02225	COG0179	Fumarylacetoacetate (FAA) hydrolase
G127AT_02240	COG0833	amino acid
G127AT_02250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G127AT_02255	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_02260	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_02265	COG2186	Transcriptional regulator
G127AT_02275	COG2233	PERMEase
G127AT_02280	COG2252	PERMEase
G127AT_02310	COG1937	Protein conserved in bacteria
G127AT_02325	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_02330	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_02335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G127AT_02340	COG2390	Transcriptional regulator
G127AT_02350	COG2807	transmembrane transport
G127AT_02355	COG0196	riboflavin kinase activity
G127AT_02370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G127AT_02375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G127AT_02390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G127AT_02395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G127AT_02405	COG0195	Participates in both transcription termination and antitermination
G127AT_02410	COG0442	prolyl-tRNA aminoacylation
G127AT_02420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G127AT_02430	COG0508	dehydrogenase complex catalyzes the overall conversion of
G127AT_02430	COG0596	Alpha beta hydrolase
G127AT_02445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G127AT_02450	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_02455	COG1309	transcriptional regulator
G127AT_02460	COG0318	PFAM AMP-dependent synthetase and ligase
G127AT_02465	COG1172	Belongs to the binding-protein-dependent transport system permease family
G127AT_02490	COG0183	Belongs to the thiolase family
G127AT_02500	COG2197	response regulator
G127AT_02505	COG4585	Histidine kinase
G127AT_02515	COG0750	zinc metalloprotease
G127AT_02520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G127AT_02585	COG0714	Associated with various cellular activities
G127AT_02600	COG0631	protein serine/threonine phosphatase activity
G127AT_02615	COG0667	Aldo Keto reductase
G127AT_02620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G127AT_02625	COG2818	Glycosylase
G127AT_02635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G127AT_02640	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G127AT_02645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G127AT_02650	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G127AT_02655	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G127AT_02660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G127AT_02665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G127AT_02670	COG0356	it plays a direct role in the translocation of protons across the membrane
G127AT_02680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G127AT_02705	COG2890	protein-(glutamine-N5) methyltransferase activity
G127AT_02715	COG1045	serine acetyltransferase
G127AT_02720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G127AT_02730	COG0083	homoserine kinase activity
G127AT_02735	COG0460	homoserine dehydrogenase
G127AT_02760	COG0018	arginyl-trna synthetase
G127AT_02780	COG2337	Toxic component of a toxin-antitoxin (TA) module
G127AT_02790	COG1609	Transcriptional regulator
G127AT_02800	COG1653	transport
G127AT_02805	COG1175	transmembrane transport
G127AT_02810	COG0395	ABC-type sugar transport system, permease component
G127AT_02815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G127AT_02825	COG1842	Phage shock protein A
G127AT_02850	COG1120	ATPase activity
G127AT_02855	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G127AT_02860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G127AT_02865	COG2375	cellular response to nickel ion
G127AT_02870	COG0154	amidase activity
G127AT_02880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G127AT_02890	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G127AT_02895	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G127AT_02900	COG4221	oxidoreductase activity
G127AT_02915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G127AT_02930	COG2197	response regulator
G127AT_02950	COG0765	amino acid transport
G127AT_02965	COG1011	Hydrolase
G127AT_02990	COG0508	dehydrogenase complex catalyzes the overall conversion of
G127AT_02990	COG0567	Dehydrogenase, E1 component
G127AT_02995	COG2409	Drug exporters of the RND superfamily
G127AT_03005	COG1595	DNA-templated transcription, initiation
G127AT_03010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G127AT_03020	COG2031	fatty acid transporter
G127AT_03030	COG1253	flavin adenine dinucleotide binding
G127AT_03075	COG0653	protein targeting
G127AT_03080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G127AT_03090	COG5401	PFAM Sporulation and spore germination
G127AT_03095	COG5002	protein histidine kinase activity
G127AT_03100	COG0745	RESPONSE REGULATOR receiver
G127AT_03120	COG0714	Associated with various cellular activities
G127AT_03145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G127AT_03155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G127AT_03185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G127AT_03205	COG1482	cell wall glycoprotein biosynthetic process
G127AT_03210	COG1960	acyl-CoA dehydrogenase activity
G127AT_03215	COG2755	lipolytic protein G-D-S-L family
G127AT_03215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G127AT_03220	COG1216	Glycosyl transferase, family 2
G127AT_03220	COG1442	glycosyl transferase family 8
G127AT_03225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G127AT_03245	COG2755	lipolytic protein G-D-S-L family
G127AT_03245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G127AT_03250	COG1215	transferase activity, transferring glycosyl groups
G127AT_03260	COG1216	Glycosyl transferase, family 2
G127AT_03305	COG1216	Glycosyl transferase, family 2
G127AT_03340	COG2755	lipolytic protein G-D-S-L family
G127AT_03340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G127AT_03345	COG1216	Glycosyl transferase, family 2
G127AT_03370	COG1216	Glycosyl transferase, family 2
G127AT_03385	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G127AT_03390	COG1088	dTDP-glucose 4,6-dehydratase activity
G127AT_03415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G127AT_03415	COG2755	lipolytic protein G-D-S-L family
G127AT_03420	COG1316	TRANSCRIPTIONal
G127AT_03455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G127AT_03485	COG1131	(ABC) transporter
G127AT_03505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G127AT_03510	COG0424	maF-like protein
G127AT_03515	COG4770	biotin carboxylase activity
G127AT_03530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G127AT_03540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G127AT_03555	COG1079	Belongs to the binding-protein-dependent transport system permease family
G127AT_03560	COG4603	Belongs to the binding-protein-dependent transport system permease family
G127AT_03565	COG3845	ABC transporter
G127AT_03575	COG1744	ABC transporter substrate-binding protein PnrA-like
G127AT_03585	COG2009	succinate dehydrogenase
G127AT_03600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G127AT_03680	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G127AT_03680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G127AT_03685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G127AT_03695	COG0477	Major facilitator Superfamily
G127AT_03705	COG1132	(ABC) transporter
G127AT_03710	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G127AT_03715	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
G127AT_03750	COG0183	Belongs to the thiolase family
G127AT_03785	COG3250	beta-galactosidase activity
G127AT_03795	COG1175	transmembrane transport
G127AT_03800	COG0395	ABC-type sugar transport system, permease component
G127AT_03830	COG1063	alcohol dehydrogenase
G127AT_03875	COG1309	transcriptional regulator
G127AT_03895	COG0583	DNA-binding transcription factor activity
G127AT_03905	COG0477	Major facilitator Superfamily
G127AT_03910	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G127AT_03915	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_03930	COG3415	Transposase
G127AT_03930	COG2801	Transposase and inactivated derivatives
G127AT_03965	COG4585	Histidine kinase
G127AT_03970	COG1131	(ABC) transporter
G127AT_03980	COG3311	Transcriptional regulator
G127AT_03985	COG1569	PIN domain
G127AT_03990	COG0477	Major facilitator Superfamily
G127AT_03995	COG3971	2-oxopent-4-enoate hydratase activity
G127AT_04005	COG0179	Fumarylacetoacetate (FAA) hydrolase
G127AT_04010	COG1802	Transcriptional regulator
G127AT_04015	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_04025	COG0659	secondary active sulfate transmembrane transporter activity
G127AT_04055	COG1335	isochorismatase
G127AT_04080	COG3177	Filamentation induced by cAMP protein fic
G127AT_04100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G127AT_04105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G127AT_04105	COG1754	DNA topoisomerase type I activity
G127AT_04140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G127AT_04150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G127AT_04165	COG3387	PFAM Glycoside hydrolase 15-related
G127AT_04175	COG0626	cystathionine gamma-synthase activity
G127AT_04190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G127AT_04195	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
G127AT_04200	COG0297	glycogen (starch) synthase activity
G127AT_04205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G127AT_04225	COG0438	transferase activity, transferring glycosyl groups
G127AT_04255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G127AT_04260	COG0489	protein tyrosine kinase activity
G127AT_04270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G127AT_04275	COG0516	GMP reductase activity
G127AT_04280	COG0488	(ABC) transporter
G127AT_04285	COG1960	acyl-CoA dehydrogenase activity
G127AT_04330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G127AT_04350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G127AT_04355	COG0456	acetyltransferase
G127AT_04365	COG0802	atpase or kinase
G127AT_04370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G127AT_04375	COG0736	holo-[acyl-carrier-protein] synthase activity
G127AT_04380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G127AT_04385	COG1072	(Pantothenic acid kinase))
G127AT_04390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G127AT_04395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G127AT_04400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G127AT_04405	COG0101	tRNA pseudouridine synthase activity
G127AT_04410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G127AT_04410	COG2755	lipolytic protein G-D-S-L family
G127AT_04415	COG0203	ribosomal protein L17
G127AT_04420	COG0202	RNA polymerase activity
G127AT_04425	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G127AT_04430	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G127AT_04435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G127AT_04440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G127AT_04445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G127AT_04450	COG0563	adenylate kinase activity
G127AT_04460	COG0200	Binds to the 23S rRNA
G127AT_04465	COG1841	ribosomal large subunit assembly
G127AT_04470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G127AT_04475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G127AT_04480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G127AT_04485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G127AT_04490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G127AT_04495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G127AT_04500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G127AT_04505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G127AT_04510	COG0255	Belongs to the universal ribosomal protein uL29 family
G127AT_04515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G127AT_04520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G127AT_04525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G127AT_04530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G127AT_04535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G127AT_04540	COG0089	rRNA binding
G127AT_04545	COG0088	Forms part of the polypeptide exit tunnel
G127AT_04550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G127AT_04555	COG0051	transcription antitermination factor activity, RNA binding
G127AT_04565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G127AT_04570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G127AT_04575	COG0049	tRNA binding
G127AT_04580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G127AT_04655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G127AT_04660	COG0085	RNA polymerase activity
G127AT_04680	COG1649	PFAM Uncharacterised BCR, COG1649
G127AT_04730	COG3973	AAA domain
G127AT_04735	COG0513	Belongs to the DEAD box helicase family
G127AT_04825	COG3938	Belongs to the proline racemase family
G127AT_04830	COG0446	pyridine nucleotide-disulphide oxidoreductase
G127AT_04845	COG1802	Transcriptional regulator
G127AT_04870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G127AT_04885	COG3655	Transcriptional regulator
G127AT_04935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G127AT_04940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G127AT_04965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G127AT_04970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G127AT_04975	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G127AT_04980	COG0302	gtp cyclohydrolase
G127AT_04985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G127AT_04995	COG0037	tRNA processing
G127AT_05000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G127AT_05010	COG0739	heme binding
G127AT_05010	COG0741	lytic transglycosylase activity
G127AT_05010	COG1196	nuclear chromosome segregation
G127AT_05055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G127AT_05060	COG0765	amino acid transport
G127AT_05065	COG0765	amino acid transport
G127AT_05070	COG1126	abc transporter atp-binding protein
G127AT_05085	COG0697	spore germination
G127AT_05105	COG0039	L-malate dehydrogenase activity
G127AT_05125	COG0514	ATP-dependent DNA helicase (RecQ)
G127AT_05145	COG0737	Belongs to the 5'-nucleotidase family
G127AT_05160	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G127AT_05175	COG3550	peptidyl-serine autophosphorylation
G127AT_05200	COG0640	Transcriptional regulator
G127AT_05205	COG1966	Carbon starvation protein
G127AT_05225	COG2910	NAD(P)H-binding
G127AT_05230	COG1278	Cold shock
G127AT_05255	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G127AT_05260	COG1737	Transcriptional regulator
G127AT_05280	COG1175	transmembrane transport
G127AT_05285	COG0395	ABC-type sugar transport system, permease component
G127AT_05295	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G127AT_05310	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05320	COG2755	lipolytic protein G-D-S-L family
G127AT_05325	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05335	COG3012	SEC-C Motif Domain Protein
G127AT_05340	COG1285	pathogenesis
G127AT_05365	COG0601	transmembrane transport
G127AT_05370	COG0747	negative chemotaxis
G127AT_05390	COG3012	SEC-C Motif Domain Protein
G127AT_05435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G127AT_05470	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05475	COG0129	dihydroxy-acid dehydratase activity
G127AT_05490	COG2376	Dihydroxyacetone kinase
G127AT_05505	COG3246	L-lysine catabolic process to acetate
G127AT_05510	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05525	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G127AT_05530	COG1414	Transcriptional regulator
G127AT_05550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G127AT_05625	COG0793	Belongs to the peptidase S41A family
G127AT_05625	COG4946	Tricorn protease homolog
G127AT_05650	COG0531	amino acid
G127AT_05655	COG4977	sequence-specific DNA binding
G127AT_05665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G127AT_05675	COG4129	membrane
G127AT_05715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_05730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_05740	COG1122	ATPase activity
G127AT_05745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G127AT_05785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G127AT_05785	COG2111	Na H antiporter
G127AT_05790	COG1006	Multisubunit Na H antiporter MnhC subunit
G127AT_05795	COG0651	ATP synthesis coupled electron transport
G127AT_05805	COG2212	antiporter activity
G127AT_05810	COG1320	monovalent cation:proton antiporter activity
G127AT_05815	COG1024	Enoyl-CoA hydratase
G127AT_05820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G127AT_05825	COG2151	metal-sulfur cluster biosynthetic enzyme
G127AT_05830	COG3396	Phenylacetate-CoA oxygenase
G127AT_05835	COG3460	Phenylacetate-CoA oxygenase
G127AT_05840	COG3396	Phenylacetate-CoA oxygenase
G127AT_05845	COG2050	protein possibly involved in aromatic compounds catabolism
G127AT_05875	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05890	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05895	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05900	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_05915	COG0535	radical SAM domain protein
G127AT_05940	COG2030	dehydratase
G127AT_05940	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_05945	COG1250	3-hydroxyacyl-CoA dehydrogenase
G127AT_05950	COG1024	Enoyl-CoA hydratase
G127AT_05965	COG0513	Belongs to the DEAD box helicase family
G127AT_05985	COG4585	Histidine kinase
G127AT_05990	COG2197	response regulator
G127AT_06005	COG1414	Transcriptional regulator
G127AT_06010	COG2986	histidine ammonia-lyase
G127AT_06015	COG1196	nuclear chromosome segregation
G127AT_06015	COG0741	lytic transglycosylase activity
G127AT_06015	COG0739	heme binding
G127AT_06040	COG1735	metal-dependent hydrolase with the TIM-barrel fold
G127AT_06045	COG2390	Transcriptional regulator
G127AT_06050	COG0477	Major facilitator Superfamily
G127AT_06060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G127AT_06065	COG1228	amidohydrolase
G127AT_06075	COG0010	Belongs to the arginase family
G127AT_06080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G127AT_06110	COG2217	Heavy metal translocating P-type atpase
G127AT_06165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G127AT_06180	COG2364	Membrane
G127AT_06235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G127AT_06255	COG4558	Periplasmic binding protein
G127AT_06260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G127AT_06265	COG1120	ATPase activity
G127AT_06280	COG0151	Belongs to the GarS family
G127AT_06285	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G127AT_06290	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
G127AT_06330	COG2514	catechol 2,3-dioxygenase activity
G127AT_06340	COG3483	tryptophan 2,3-dioxygenase activity
G127AT_06355	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G127AT_06360	COG0047	phosphoribosylformylglycinamidine synthase activity
G127AT_06380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G127AT_06385	COG1116	anion transmembrane transporter activity
G127AT_06395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G127AT_06400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G127AT_06420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G127AT_06450	COG4221	oxidoreductase activity
G127AT_06455	COG0287	Prephenate dehydrogenase
G127AT_06455	COG1605	Chorismate mutase
G127AT_06465	COG1131	(ABC) transporter
G127AT_06500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G127AT_06510	COG3275	phosphorelay sensor kinase activity
G127AT_06525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G127AT_06550	COG2205	protein histidine kinase activity
G127AT_06555	COG2358	TRAP transporter, solute receptor (TAXI family
G127AT_06580	COG0006	proline dipeptidase activity
G127AT_06585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G127AT_06590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G127AT_06620	COG1129	ABC transporter
G127AT_06625	COG1063	alcohol dehydrogenase
G127AT_06630	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_06635	COG3265	gluconokinase activity
G127AT_06645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G127AT_06655	COG0137	argininosuccinate synthase activity
G127AT_06675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G127AT_06680	COG3415	Transposase
G127AT_06680	COG2801	Transposase and inactivated derivatives
G127AT_06690	COG0494	nUDIX hydrolase
G127AT_06720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G127AT_06730	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G127AT_06735	COG3340	Belongs to the peptidase S51 family
G127AT_06740	COG0583	DNA-binding transcription factor activity
G127AT_06770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G127AT_06780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G127AT_06785	COG1120	ATPase activity
G127AT_06815	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
G127AT_06815	COG0778	Nitroreductase
G127AT_06820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_06855	COG0519	Catalyzes the synthesis of GMP from XMP
G127AT_06855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G127AT_06885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G127AT_06885	COG0519	Catalyzes the synthesis of GMP from XMP
G127AT_06905	COG2195	Cleaves the N-terminal amino acid of tripeptides
G127AT_06935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_06960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G127AT_06965	COG0300	oxidoreductase activity
G127AT_06980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G127AT_07020	COG4585	Histidine kinase
G127AT_07025	COG2197	response regulator
G127AT_07035	COG4152	abc transporter atp-binding protein
G127AT_07050	COG1063	alcohol dehydrogenase
G127AT_07080	COG0542	response to heat
G127AT_07115	COG4716	Myosin-crossreactive antigen
G127AT_07125	COG1414	Transcriptional regulator
G127AT_07155	COG0583	DNA-binding transcription factor activity
G127AT_07185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G127AT_07215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G127AT_07235	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_07250	COG1070	Carbohydrate kinase
G127AT_07255	COG2115	Belongs to the xylose isomerase family
G127AT_07260	COG3458	cephalosporin-C deacetylase activity
G127AT_07265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G127AT_07275	COG1472	Belongs to the glycosyl hydrolase 3 family
G127AT_07280	COG0395	ABC-type sugar transport system, permease component
G127AT_07285	COG1175	transmembrane transport
G127AT_07310	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_07315	COG1309	transcriptional regulator
G127AT_07355	COG2186	Transcriptional regulator
G127AT_07365	COG2084	Dehydrogenase
G127AT_07370	COG2610	gluconate transmembrane transporter activity
G127AT_07375	COG0318	PFAM AMP-dependent synthetase and ligase
G127AT_07380	COG1960	acyl-CoA dehydrogenase activity
G127AT_07400	COG1960	acyl-CoA dehydrogenase activity
G127AT_07410	COG0183	Belongs to the thiolase family
G127AT_07440	COG2409	Drug exporters of the RND superfamily
G127AT_07450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G127AT_07455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G127AT_07480	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_07490	COG2409	Drug exporters of the RND superfamily
G127AT_07500	COG2271	Major facilitator Superfamily
G127AT_07515	COG0045	succinate-CoA ligase (ADP-forming) activity
G127AT_07520	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_07525	COG1309	transcriptional regulator
G127AT_07545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G127AT_07555	COG1716	ATPase activity
G127AT_07560	COG1716	ATPase activity
G127AT_07580	COG0515	serine threonine protein kinase
G127AT_07585	COG2815	serine threonine protein kinase
G127AT_07585	COG0515	serine threonine protein kinase
G127AT_07600	COG3764	Sortase (surface protein transpeptidase)
G127AT_07610	COG0457	Tetratricopeptide repeat
G127AT_07610	COG0705	Rhomboid family
G127AT_07635	COG0765	amino acid transport
G127AT_07640	COG0765	amino acid transport
G127AT_07645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G127AT_07650	COG1126	abc transporter atp-binding protein
G127AT_07655	COG2267	carboxylic ester hydrolase activity
G127AT_07680	COG0789	Transcriptional regulator
G127AT_07685	COG2814	Major facilitator Superfamily
G127AT_07730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G127AT_07735	COG0187	DNA topoisomerase II activity
G127AT_07740	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
G127AT_07745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G127AT_07750	COG0592	DNA-directed DNA polymerase activity
G127AT_07755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G127AT_07760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G127AT_07765	COG0594	ribonuclease P activity
G127AT_07770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G127AT_07775	COG0706	membrane insertase activity
G127AT_07785	COG0357	Ribosomal RNA small subunit methyltransferase G
G127AT_07800	COG3415	Transposase
G127AT_07800	COG2801	Transposase and inactivated derivatives
G127AT_07805	COG1192	Involved in chromosome partitioning
G127AT_07815	COG1181	Belongs to the D-alanine--D-alanine ligase family
G127AT_07820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G127AT_07825	COG3118	belongs to the thioredoxin family
G127AT_07830	COG0492	ferredoxin-NADP+ reductase activity
G127AT_07845	COG0617	tRNA 3'-terminal CCA addition
G127AT_07860	COG0360	Binds together with S18 to 16S ribosomal RNA
G127AT_07870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G127AT_07875	COG0359	binds to the 23S rRNA
G127AT_07880	COG0305	Participates in initiation and elongation during chromosome replication
G127AT_07900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G127AT_07920	COG1950	PFAM Membrane protein of
G127AT_07925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G127AT_07935	COG0022	dehydrogenase e1 component
G127AT_07985	COG1121	(ABC) transporter
G127AT_07990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G127AT_08010	COG1136	(ABC) transporter
G127AT_08030	COG1396	sequence-specific DNA binding
G127AT_08065	COG0477	Major facilitator Superfamily
G127AT_08100	COG0076	glutamate decarboxylase activity
G127AT_08110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G127AT_08115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G127AT_08120	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G127AT_08125	COG0776	regulation of translation
G127AT_08145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G127AT_08165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G127AT_08170	COG1022	Amp-dependent synthetase and ligase
G127AT_08175	COG0657	acetylesterase activity
G127AT_08195	COG0456	acetyltransferase
G127AT_08230	COG1064	alcohol dehydrogenase
G127AT_08245	COG0717	Belongs to the dCTP deaminase family
G127AT_08260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G127AT_08260	COG1017	nitric oxide dioxygenase activity
G127AT_08280	COG1136	(ABC) transporter
G127AT_08305	COG2890	protein-(glutamine-N5) methyltransferase activity
G127AT_08335	COG1175	transmembrane transport
G127AT_08340	COG0395	ABC-type sugar transport system, permease component
G127AT_08380	COG1609	Transcriptional regulator
G127AT_08410	COG3119	arylsulfatase activity
G127AT_08415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G127AT_08435	COG0443	Heat shock 70 kDa protein
G127AT_08440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G127AT_08445	COG0484	heat shock protein binding
G127AT_08450	COG0789	Transcriptional regulator
G127AT_08480	COG2813	Specifically methylates the guanine in position
G127AT_08485	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G127AT_08530	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G127AT_08535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G127AT_08555	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
G127AT_08560	COG0738	Major facilitator superfamily
G127AT_08580	COG3590	peptidase
G127AT_08625	COG0423	glycine-tRNA ligase activity
G127AT_08635	COG1053	succinate dehydrogenase
G127AT_08640	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G127AT_08645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G127AT_08675	COG3253	May function as heme-dependent peroxidase
G127AT_08680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G127AT_08685	COG0181	hydroxymethylbilane synthase activity
G127AT_08695	COG0113	porphobilinogen synthase activity
G127AT_08700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G127AT_08715	COG1131	(ABC) transporter
G127AT_08760	COG2079	MmgE PrpD family protein
G127AT_08765	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G127AT_08800	COG0747	negative chemotaxis
G127AT_08805	COG0601	transmembrane transport
G127AT_08810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_08815	COG4172	Belongs to the ABC transporter superfamily
G127AT_08840	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_08845	COG0189	ligase activity
G127AT_08845	COG4067	protein conserved in archaea
G127AT_08850	COG0189	ligase activity
G127AT_08850	COG0569	domain protein
G127AT_08855	COG1725	Transcriptional regulator
G127AT_08895	COG1834	amidinotransferase
G127AT_08900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G127AT_08910	COG3104	oligopeptide transport
G127AT_08915	COG1216	Glycosyl transferase, family 2
G127AT_08925	COG1309	transcriptional regulator
G127AT_08930	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G127AT_08945	COG2186	Transcriptional regulator
G127AT_08990	COG1064	alcohol dehydrogenase
G127AT_09045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G127AT_09055	COG0477	Major facilitator Superfamily
G127AT_09060	COG2186	Transcriptional regulator
G127AT_09065	COG1070	Carbohydrate kinase
G127AT_09070	COG3347	Dehydrogenase
G127AT_09070	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_09090	COG1172	Belongs to the binding-protein-dependent transport system permease family
G127AT_09095	COG1172	Belongs to the binding-protein-dependent transport system permease family
G127AT_09100	COG1129	ABC transporter
G127AT_09105	COG1609	Transcriptional regulator
G127AT_09115	COG1609	Transcriptional regulator
G127AT_09120	COG0673	inositol 2-dehydrogenase activity
G127AT_09135	COG0673	inositol 2-dehydrogenase activity
G127AT_09140	COG1609	Transcriptional regulator
G127AT_09150	COG4948	Mandelate Racemase Muconate Lactonizing
G127AT_09155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G127AT_09170	COG1316	TRANSCRIPTIONal
G127AT_09200	COG1136	(ABC) transporter
G127AT_09240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G127AT_09245	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G127AT_09250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G127AT_09260	COG1309	transcriptional regulator
G127AT_09300	COG0095	Lipoate-protein ligase
G127AT_09315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_09330	COG0395	ABC-type sugar transport system, permease component
G127AT_09335	COG1175	transmembrane transport
G127AT_09345	COG1876	peptidase activity
G127AT_09360	COG0077	Prephenate dehydratase
G127AT_09365	COG1597	lipid kinase activity
G127AT_09370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G127AT_09375	COG0561	phosphatase activity
G127AT_09380	COG1316	TRANSCRIPTIONal
G127AT_09390	COG1316	TRANSCRIPTIONal
G127AT_09405	COG1487	ribonuclease activity
G127AT_09425	COG2423	ornithine cyclodeaminase activity
G127AT_09440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G127AT_09465	COG0366	Alpha amylase catalytic
G127AT_09470	COG1653	transport
G127AT_09475	COG4209	transmembrane transport
G127AT_09480	COG0395	ABC-type sugar transport system, permease component
G127AT_09495	COG0640	Transcriptional regulator
G127AT_09545	COG2207	Transcriptional regulator
G127AT_09560	COG1129	ABC transporter
G127AT_09575	COG1404	Belongs to the peptidase S8 family
G127AT_09575	COG4412	M6 family metalloprotease domain protein
G127AT_09580	COG0745	RESPONSE REGULATOR receiver
G127AT_09595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G127AT_09635	COG3525	Glycosyl hydrolase, family 20, catalytic domain
G127AT_09645	COG0569	domain protein
G127AT_09650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G127AT_09680	COG0017	Asparaginyl-tRNA synthetase
G127AT_09685	COG0406	alpha-ribazole phosphatase activity
G127AT_09695	COG0785	Cytochrome C biogenesis protein
G127AT_09700	COG1333	cytochrome c biogenesis protein
G127AT_09705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G127AT_09720	COG2814	Major facilitator Superfamily
G127AT_09725	COG0789	Transcriptional regulator
G127AT_09730	COG4948	Mandelate Racemase Muconate Lactonizing
G127AT_09765	COG1575	Belongs to the MenA family. Type 1 subfamily
G127AT_09780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G127AT_09785	COG2326	polyphosphate kinase activity
G127AT_09795	COG2226	methyltransferase
G127AT_09800	COG0142	geranyltranstransferase activity
G127AT_09825	COG2197	response regulator
G127AT_09830	COG4585	Histidine kinase
G127AT_09840	COG1666	GTP binding
G127AT_09850	COG1609	Transcriptional regulator
G127AT_09895	COG0483	inositol monophosphate 1-phosphatase activity
G127AT_09900	COG0739	heme binding
G127AT_09910	COG0366	Alpha amylase catalytic
G127AT_09915	COG2182	Extracellular solute-binding protein
G127AT_09925	COG3833	ABC-type maltose transport systems, permease component
G127AT_09975	COG0598	Magnesium transport protein CorA
G127AT_09980	COG0431	NADPH-dependent FMN reductase
G127AT_09985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_09995	COG0601	transmembrane transport
G127AT_10000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_10005	COG4172	Belongs to the ABC transporter superfamily
G127AT_10010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_10070	COG2030	dehydratase
G127AT_10080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G127AT_10085	COG4941	Belongs to the sigma-70 factor family
G127AT_10140	COG2197	response regulator
G127AT_10160	COG0436	Aminotransferase
G127AT_10165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G127AT_10175	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G127AT_10185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G127AT_10190	COG0081	regulation of translation
G127AT_10195	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_10210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G127AT_10220	COG0531	amino acid
G127AT_10240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G127AT_10260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G127AT_10270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_10275	COG1414	Transcriptional regulator
G127AT_10285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G127AT_10300	COG0604	alcohol dehydrogenase
G127AT_10300	COG3321	synthase
G127AT_10325	COG0745	RESPONSE REGULATOR receiver
G127AT_10330	COG2205	protein histidine kinase activity
G127AT_10345	COG0477	Major facilitator Superfamily
G127AT_10350	COG0733	neurotransmitter:sodium symporter activity
G127AT_10360	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G127AT_10365	COG0222	ribosome binding
G127AT_10375	COG1609	Transcriptional regulator
G127AT_10380	COG1653	transport
G127AT_10385	COG0395	ABC-type sugar transport system, permease component
G127AT_10390	COG1175	transmembrane transport
G127AT_10400	COG2814	Major facilitator Superfamily
G127AT_10410	COG1653	transport
G127AT_10415	COG1175	transmembrane transport
G127AT_10420	COG0395	ABC-type sugar transport system, permease component
G127AT_10430	COG1132	(ABC) transporter
G127AT_10435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G127AT_10480	COG0531	amino acid
G127AT_10515	COG4214	carbohydrate transport
G127AT_10530	COG1609	Transcriptional regulator
G127AT_10540	COG4213	ABC transporter substrate-binding protein
G127AT_10550	COG4214	carbohydrate transport
G127AT_10560	COG2160	L-arabinose isomerase activity
G127AT_10565	COG3547	Transposase (IS116 IS110 IS902 family)
G127AT_10585	COG1780	Probably involved in ribonucleotide reductase function
G127AT_10590	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G127AT_10595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G127AT_10610	COG2011	ABC-type metal ion transport system permease component
G127AT_10615	COG1464	Belongs to the NlpA lipoprotein family
G127AT_10625	COG3290	protein histidine kinase activity
G127AT_10680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G127AT_10690	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G127AT_10705	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_10710	COG1309	transcriptional regulator
G127AT_10715	COG0318	PFAM AMP-dependent synthetase and ligase
G127AT_10730	COG1960	acyl-CoA dehydrogenase activity
G127AT_10740	COG0183	Belongs to the thiolase family
G127AT_10770	COG0328	RNA-DNA hybrid ribonuclease activity
G127AT_10800	COG2382	esterase
G127AT_10815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_10820	COG0601	transmembrane transport
G127AT_10825	COG4166	transmembrane transport
G127AT_10840	COG1116	anion transmembrane transporter activity
G127AT_10845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G127AT_10850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G127AT_10865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G127AT_10890	COG2375	cellular response to nickel ion
G127AT_10955	COG0444	Belongs to the ABC transporter superfamily
G127AT_10965	COG1228	amidohydrolase
G127AT_10970	COG1473	amidohydrolase
G127AT_10980	COG3485	protocatechuate 3,4-dioxygenase
G127AT_11000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G127AT_11025	COG0477	Major facilitator Superfamily
G127AT_11035	COG0406	alpha-ribazole phosphatase activity
G127AT_11060	COG0702	epimerase
G127AT_11070	COG0740	serine-type endopeptidase activity
G127AT_11075	COG0740	serine-type endopeptidase activity
G127AT_11090	COG1140	nitrate reductase beta subunit
G127AT_11105	COG0521	Mo-molybdopterin cofactor biosynthetic process
G127AT_11105	COG0315	cyclic pyranopterin monophosphate synthase activity
G127AT_11110	COG0314	molybdopterin synthase activity
G127AT_11115	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G127AT_11135	COG0315	cyclic pyranopterin monophosphate synthase activity
G127AT_11155	COG3585	molybdate ion transport
G127AT_11175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G127AT_11200	COG4552	Acetyltransferase involved in intracellular survival and related
G127AT_11210	COG2814	Major facilitator Superfamily
G127AT_11220	COG0456	acetyltransferase
G127AT_11240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G127AT_11245	COG0385	Bile acid
G127AT_11260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G127AT_11265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G127AT_11275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G127AT_11295	COG1414	Transcriptional regulator
G127AT_11300	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
G127AT_11315	COG0579	oxidoreductase
G127AT_11320	COG0488	(ABC) transporter
G127AT_11365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G127AT_11365	COG0519	Catalyzes the synthesis of GMP from XMP
G127AT_11375	COG4941	Belongs to the sigma-70 factor family
G127AT_11385	COG0584	glycerophosphoryl diester phosphodiesterase
G127AT_11405	COG0045	succinate-CoA ligase (ADP-forming) activity
G127AT_11425	COG0138	bifunctional purine biosynthesis protein purh
G127AT_11435	COG1834	amidinotransferase
G127AT_11440	COG1136	(ABC) transporter
G127AT_11440	COG0577	efflux transmembrane transporter activity
G127AT_11445	COG1136	(ABC) transporter
G127AT_11460	COG1132	(ABC) transporter
G127AT_11465	COG1132	(ABC) transporter
G127AT_11490	COG0538	isocitrate dehydrogenase activity
G127AT_11495	COG2217	Heavy metal translocating P-type atpase
G127AT_11515	COG1175	transmembrane transport
G127AT_11520	COG0395	ABC-type sugar transport system, permease component
G127AT_11525	COG1472	Belongs to the glycosyl hydrolase 3 family
G127AT_11535	COG0363	glucosamine-6-phosphate deaminase activity
G127AT_11565	COG0395	ABC-type sugar transport system, permease component
G127AT_11570	COG1175	transmembrane transport
G127AT_11580	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
G127AT_11595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G127AT_11600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G127AT_11635	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G127AT_11645	COG1349	DNA-binding transcription factor activity
G127AT_11650	COG2017	converts alpha-aldose to the beta-anomer
G127AT_11660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G127AT_11690	COG1131	(ABC) transporter
G127AT_11705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G127AT_11730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G127AT_11735	COG0745	RESPONSE REGULATOR receiver
G127AT_11745	COG4044	May play a role in the intracellular transport of hydrophobic ligands
G127AT_11765	COG0588	phosphoglycerate mutase activity
G127AT_11770	COG0704	Plays a role in the regulation of phosphate uptake
G127AT_11775	COG5002	protein histidine kinase activity
G127AT_11780	COG0745	RESPONSE REGULATOR receiver
G127AT_11805	COG0215	cysteine-tRNA ligase activity
G127AT_11810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G127AT_11820	COG3842	ATPase activity
G127AT_11840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G127AT_11855	COG1278	Cold shock
G127AT_11865	COG0459	protein refolding
G127AT_11875	COG2205	protein histidine kinase activity
G127AT_11880	COG0745	RESPONSE REGULATOR receiver
G127AT_11900	COG0513	Belongs to the DEAD box helicase family
G127AT_11915	COG1278	Cold shock
G127AT_11930	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G127AT_11940	COG0791	NLP P60 protein
G127AT_11950	COG1388	LysM domain
G127AT_11950	COG3942	CHAP domain
G127AT_11955	COG2706	6-phosphogluconolactonase activity
G127AT_12005	COG0686	Belongs to the AlaDH PNT family
G127AT_12010	COG1937	Protein conserved in bacteria
G127AT_12020	COG0446	pyridine nucleotide-disulphide oxidoreductase
G127AT_12035	COG1970	mechanosensitive ion channel activity
G127AT_12050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G127AT_12095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G127AT_12125	COG0656	L-ascorbic acid biosynthetic process
G127AT_12135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G127AT_12150	COG1643	Atp-dependent helicase
G127AT_12160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G127AT_12185	COG1331	Highly conserved protein containing a thioredoxin domain
G127AT_12220	COG1362	aminopeptidase activity
G127AT_12235	COG1760	l-serine dehydratase
G127AT_12255	COG3177	Filamentation induced by cAMP protein fic
G127AT_12265	COG2827	Endonuclease containing a URI domain
G127AT_12270	COG1832	CoA-binding protein
G127AT_12285	COG1335	isochorismatase
G127AT_12290	COG2076	Multidrug Resistance protein
G127AT_12310	COG1131	(ABC) transporter
G127AT_12350	COG2855	membrane
G127AT_12360	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G127AT_12365	COG1472	Belongs to the glycosyl hydrolase 3 family
G127AT_12370	COG3876	Protein conserved in bacteria
G127AT_12375	COG0747	negative chemotaxis
G127AT_12380	COG0601	transmembrane transport
G127AT_12385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_12390	COG0444	Belongs to the ABC transporter superfamily
G127AT_12395	COG4608	Belongs to the ABC transporter superfamily
G127AT_12400	COG1737	Transcriptional regulator
G127AT_12405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G127AT_12445	COG1487	ribonuclease activity
G127AT_12460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G127AT_12465	COG0084	hydrolase, TatD family'
G127AT_12470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G127AT_12615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G127AT_12620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G127AT_12625	COG0488	(ABC) transporter
G127AT_12630	COG3835	regulator
G127AT_12635	COG1929	Belongs to the glycerate kinase type-1 family
G127AT_12640	COG2610	gluconate transmembrane transporter activity
G127AT_12650	COG1917	Cupin 2, conserved barrel domain protein
G127AT_12655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G127AT_12670	COG1403	HNH endonuclease
G127AT_12685	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G127AT_12690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G127AT_12695	COG0318	PFAM AMP-dependent synthetase and ligase
G127AT_12715	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G127AT_12720	COG3265	gluconokinase activity
G127AT_12725	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G127AT_12730	COG1309	transcriptional regulator
G127AT_12750	COG0193	aminoacyl-tRNA hydrolase activity
G127AT_12760	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G127AT_12780	COG0124	histidyl-tRNA synthetase
G127AT_12785	COG0148	phosphopyruvate hydratase activity
G127AT_12800	COG1404	Belongs to the peptidase S8 family
G127AT_12840	COG1704	LemA family
G127AT_12845	COG0501	Belongs to the peptidase M48B family
G127AT_12850	COG3214	Protein conserved in bacteria
G127AT_12860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G127AT_12870	COG1960	acyl-CoA dehydrogenase activity
G127AT_12875	COG0318	PFAM AMP-dependent synthetase and ligase
G127AT_12880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G127AT_12900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G127AT_12910	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G127AT_12920	COG0114	fumarate hydratase activity
G127AT_12935	COG1722	exodeoxyribonuclease VII activity
G127AT_12940	COG1570	exodeoxyribonuclease VII activity
G127AT_12945	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G127AT_12955	COG0191	fructose-bisphosphate aldolase activity
G127AT_12965	COG1619	proteins homologs of microcin C7 resistance protein MccF
G127AT_12970	COG1733	regulation of RNA biosynthetic process
G127AT_12980	COG1322	Protein conserved in bacteria
G127AT_12990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G127AT_13010	COG0012	GTP binding
G127AT_13020	COG2026	Addiction module toxin, RelE StbE family
G127AT_13070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G127AT_13110	COG1487	ribonuclease activity
G127AT_13125	COG3549	Plasmid maintenance system killer
G127AT_13140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G127AT_13145	COG0697	spore germination
G127AT_13155	COG3833	ABC-type maltose transport systems, permease component
G127AT_13175	COG2801	Transposase and inactivated derivatives
G127AT_13175	COG3415	Transposase
G127AT_13205	COG1028	Short-chain dehydrogenase reductase Sdr
G127AT_13215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G127AT_13225	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G127AT_13240	COG2814	Major facilitator Superfamily
G127AT_13260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G127AT_13265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G127AT_13275	COG1464	Belongs to the NlpA lipoprotein family
G127AT_13285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G127AT_13290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G127AT_13295	COG0509	glycine decarboxylation via glycine cleavage system
G127AT_13300	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G127AT_13300	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G127AT_13315	COG4166	transmembrane transport
G127AT_13325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_13330	COG4172	Belongs to the ABC transporter superfamily
G127AT_13335	COG1217	gtp-binding protein TYPA
G127AT_13340	COG1196	nuclear chromosome segregation
G127AT_13340	COG0741	lytic transglycosylase activity
G127AT_13340	COG0739	heme binding
G127AT_13345	COG1024	Enoyl-CoA hydratase
G127AT_13375	COG2171	N-acyltransferase activity
G127AT_13380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G127AT_13400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G127AT_13405	COG1012	belongs to the aldehyde dehydrogenase family
G127AT_13410	COG2211	Major facilitator Superfamily
G127AT_13430	COG2239	Acts as a magnesium transporter
G127AT_13445	COG0006	proline dipeptidase activity
G127AT_13460	COG0513	Belongs to the DEAD box helicase family
G127AT_13485	COG0210	DNA helicase
G127AT_13515	COG3480	Lon protease (S16) C-terminal proteolytic domain
G127AT_13520	COG1615	UPF0182 protein
G127AT_13565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G127AT_13565	COG0352	thiamine-phosphate diphosphorylase activity
G127AT_13565	COG0351	phosphomethylpyrimidine kinase
G127AT_13570	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G127AT_13585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G127AT_13595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G127AT_13620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G127AT_13635	COG4721	ABC-type cobalt transport system, permease component
G127AT_13640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G127AT_13665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G127AT_13670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G127AT_13675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G127AT_13685	COG0586	Pfam SNARE associated Golgi protein
G127AT_13770	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G127AT_13775	COG2884	Cell division ATP-binding protein ftsE
G127AT_13780	COG2177	Part of the ABC transporter FtsEX involved in
G127AT_13785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G127AT_13820	COG0667	Aldo Keto reductase
G127AT_13825	COG0483	inositol monophosphate 1-phosphatase activity
G127AT_13835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G127AT_13840	COG1122	ATPase activity
G127AT_13845	COG1268	BioY protein
G127AT_13865	COG2409	Drug exporters of the RND superfamily
G127AT_13870	COG1511	domain protein
G127AT_13875	COG1082	Xylose isomerase domain protein TIM barrel
G127AT_13880	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G127AT_13885	COG0129	dihydroxy-acid dehydratase activity
G127AT_13890	COG0028	Belongs to the TPP enzyme family
G127AT_13895	COG0440	acetolactate synthase activity
G127AT_13900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G127AT_13930	COG1914	H( )-stimulated, divalent metal cation uptake system
G127AT_13935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G127AT_13940	COG4336	lyase activity
G127AT_13945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G127AT_13950	COG4770	biotin carboxylase activity
G127AT_13955	COG0473	3-isopropylmalate dehydrogenase activity
G127AT_13960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G127AT_13965	COG0179	Fumarylacetoacetate (FAA) hydrolase
G127AT_13975	COG0583	DNA-binding transcription factor activity
G127AT_13980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G127AT_14000	COG3311	Transcriptional regulator
G127AT_14005	COG1569	PIN domain
G127AT_14020	COG0386	Belongs to the glutathione peroxidase family
G127AT_14025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G127AT_14055	COG3012	SEC-C Motif Domain Protein
G127AT_14090	COG2124	cytochrome p450
G127AT_14095	COG1063	alcohol dehydrogenase
G127AT_14120	COG2368	4-hydroxyphenylacetate
G127AT_14140	COG2159	amidohydrolase
G127AT_14155	COG3842	ATPase activity
G127AT_14165	COG2188	Transcriptional regulator
G127AT_14175	COG2508	Transcriptional regulator
G127AT_14180	COG2159	amidohydrolase
G127AT_14185	COG3384	dioxygenase
G127AT_14195	COG0473	3-isopropylmalate dehydrogenase activity
G127AT_14195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G127AT_14200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G127AT_14215	COG3842	ATPase activity
G127AT_14220	COG2186	Transcriptional regulator
G127AT_14240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G127AT_14280	COG4608	Belongs to the ABC transporter superfamily
G127AT_14285	COG0444	Belongs to the ABC transporter superfamily
G127AT_14295	COG0747	negative chemotaxis
G127AT_14300	COG0179	Fumarylacetoacetate (FAA) hydrolase
G127AT_14375	COG0631	protein serine/threonine phosphatase activity
G127AT_14390	COG2815	serine threonine protein kinase
G127AT_14390	COG0515	serine threonine protein kinase
G127AT_14405	COG0714	Associated with various cellular activities
G127AT_14425	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G127AT_14430	COG0066	3-isopropylmalate dehydratase activity
G127AT_14435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G127AT_14445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G127AT_14450	COG1181	Belongs to the D-alanine--D-alanine ligase family
G127AT_14470	COG0742	ribosomal rna small subunit methyltransferase
G127AT_14480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G127AT_14485	COG0714	Associated with various cellular activities
G127AT_14495	COG1305	Transglutaminase-like
G127AT_14505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G127AT_14510	COG0571	ribonuclease III activity
G127AT_14515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G127AT_14545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G127AT_14550	COG0321	lipoyl(octanoyl) transferase activity
G127AT_14555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G127AT_14585	COG0228	four-way junction DNA binding
G127AT_14590	COG1837	Belongs to the UPF0109 family
G127AT_14595	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G127AT_14600	COG0336	Belongs to the RNA methyltransferase TrmD family
G127AT_14615	COG0243	molybdopterin cofactor binding
G127AT_14620	COG2223	nitrite transmembrane transporter activity
G127AT_14630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G127AT_14630	COG1648	precorrin-2 dehydrogenase activity
G127AT_14635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G127AT_14660	COG0335	large ribosomal subunit rRNA binding
G127AT_14665	COG0681	Belongs to the peptidase S26 family
G127AT_14670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G127AT_14680	COG0792	nuclease activity
G127AT_14700	COG4974	Belongs to the 'phage' integrase family
G127AT_14710	COG0052	Belongs to the universal ribosomal protein uS2 family
G127AT_14715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G127AT_14720	COG0528	UMP kinase activity
G127AT_14725	COG0233	cytoplasmic translational termination
G127AT_14785	COG0482	sulfurtransferase activity
G127AT_14790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G127AT_14795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G127AT_14800	COG0154	amidase activity
G127AT_14805	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G127AT_14810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G127AT_14820	COG4721	ABC-type cobalt transport system, permease component
G127AT_14825	COG1122	ATPase activity
G127AT_14855	COG4948	Mandelate Racemase Muconate Lactonizing
G127AT_14860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G127AT_14875	COG0583	DNA-binding transcription factor activity
G127AT_14900	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G127AT_14910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G127AT_14915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G127AT_14930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G127AT_14945	COG0667	Aldo Keto reductase
G127AT_14950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G127AT_15030	COG0723	plastoquinol--plastocyanin reductase activity
G127AT_15035	COG1946	Acyl-CoA thioesterase
G127AT_15055	COG0668	transmembrane transport
G127AT_15085	COG2132	Multicopper oxidase
G127AT_15095	COG2197	response regulator
G127AT_15115	COG0544	peptidyl-prolyl cis-trans isomerase activity
G127AT_15120	COG0740	serine-type endopeptidase activity
G127AT_15125	COG0740	serine-type endopeptidase activity
G127AT_15130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G127AT_15150	COG0756	dUTP diphosphatase activity
G127AT_15165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G127AT_15170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G127AT_15175	COG1024	Enoyl-CoA hydratase
G127AT_15175	COG1250	3-hydroxyacyl-CoA dehydrogenase
G127AT_15180	COG0183	Belongs to the thiolase family
G127AT_15185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G127AT_15195	COG2267	carboxylic ester hydrolase activity
G127AT_15245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G127AT_15255	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G127AT_15265	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
G127AT_15270	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G127AT_15280	COG2801	Transposase and inactivated derivatives
G127AT_15280	COG3415	Transposase
G127AT_15285	COG0217	transcriptional regulatory protein
G127AT_15290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G127AT_15295	COG0632	four-way junction helicase activity
G127AT_15300	COG2255	four-way junction helicase activity
G127AT_15310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G127AT_15315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G127AT_15320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G127AT_15345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G127AT_15355	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G127AT_15360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G127AT_15370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G127AT_15375	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G127AT_15380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G127AT_15385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G127AT_15390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G127AT_15395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G127AT_15400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G127AT_15430	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G127AT_15435	COG0540	Belongs to the ATCase OTCase family
G127AT_15440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G127AT_15450	COG0505	Belongs to the CarA family
G127AT_15455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G127AT_15460	COG0284	orotidine-5'-phosphate decarboxylase activity
G127AT_15465	COG0194	GDP metabolic process
G127AT_15470	COG1758	RNA polymerase activity
G127AT_15480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G127AT_15485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G127AT_15490	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G127AT_15500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G127AT_15505	COG0140	phosphoribosyl-ATP diphosphatase activity
G127AT_15510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G127AT_15515	COG0107	imidazoleglycerol-phosphate synthase activity
G127AT_15535	COG0134	indole-3-glycerol-phosphate synthase activity
G127AT_15540	COG0133	tryptophan synthase activity
G127AT_15545	COG0159	tryptophan synthase activity
G127AT_15550	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G127AT_15555	COG0070	glutamate synthase
G127AT_15555	COG0069	glutamate synthase activity
G127AT_15555	COG0067	glutamate synthase
G127AT_15580	COG2050	protein possibly involved in aromatic compounds catabolism
G127AT_15595	COG0539	negative regulation of cytoplasmic translation
G127AT_15600	COG0237	dephospho-CoA kinase activity
G127AT_15605	COG0556	nucleotide-excision repair
G127AT_15615	COG0322	excinuclease ABC activity
G127AT_15620	COG1660	Displays ATPase and GTPase activities
G127AT_15625	COG1481	regulation of sporulation
G127AT_15635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G127AT_15640	COG0126	phosphoglycerate kinase activity
G127AT_15645	COG0149	triose-phosphate isomerase activity
G127AT_15650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G127AT_15660	COG0363	glucosamine-6-phosphate deaminase activity
G127AT_15675	COG0166	Belongs to the GPI family
G127AT_15680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G127AT_15690	COG0109	protoheme IX farnesyltransferase activity
G127AT_15700	COG1612	heme a metabolic process
G127AT_15720	COG0396	ATPase activity
G127AT_15725	COG2151	metal-sulfur cluster biosynthetic enzyme
G127AT_15730	COG0339	signal peptide processing
G127AT_15735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G127AT_15760	COG0525	valine-tRNA ligase activity
G127AT_15770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G127AT_15780	COG0747	negative chemotaxis
G127AT_15785	COG1309	transcriptional regulator
G127AT_15790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G127AT_15795	COG0285	dihydrofolate synthase activity
G127AT_15805	COG0105	UTP biosynthetic process
G127AT_15815	COG1530	ribonuclease E activity
G127AT_15825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G127AT_15830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G127AT_15835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G127AT_15840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G127AT_15845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G127AT_15855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G127AT_15865	COG0799	negative regulation of ribosome biogenesis
G127AT_15895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G127AT_15900	COG0732	type I restriction modification DNA specificity domain
G127AT_15910	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G127AT_15915	COG5290	Psort location Cytoplasmic, score
G127AT_15920	COG1196	nuclear chromosome segregation