locus-tag	class	description
ATC03_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ATC03_00010	COG0592	DNA-directed DNA polymerase activity
ATC03_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATC03_00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ATC03_00025	COG0187	DNA topoisomerase II activity
ATC03_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATC03_00070	COG0705	Rhomboid family
ATC03_00070	COG0457	Tetratricopeptide repeat
ATC03_00090	COG2815	serine threonine protein kinase
ATC03_00090	COG0515	serine threonine protein kinase
ATC03_00095	COG0515	serine threonine protein kinase
ATC03_00100	COG0768	penicillin binding
ATC03_00115	COG1716	ATPase activity
ATC03_00120	COG1716	ATPase activity
ATC03_00145	COG1595	DNA-templated transcription, initiation
ATC03_00175	COG1136	(ABC) transporter
ATC03_00240	COG2211	Major facilitator Superfamily
ATC03_00265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ATC03_00275	COG1064	alcohol dehydrogenase
ATC03_00310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_00315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATC03_00320	COG3119	arylsulfatase activity
ATC03_00345	COG0038	chloride channel
ATC03_00370	COG1733	regulation of RNA biosynthetic process
ATC03_00375	COG0277	FAD linked oxidase domain protein
ATC03_00390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATC03_00400	COG3591	Belongs to the peptidase S1B family
ATC03_00400	COG1864	DNA RNA non-specific endonuclease
ATC03_00425	COG3708	Transcriptional regulator
ATC03_00425	COG2207	Transcriptional regulator
ATC03_00430	COG5006	permease, DMT superfamily
ATC03_00455	COG0672	)-iron permease
ATC03_00460	COG2822	iron ion transport
ATC03_00465	COG2837	iron assimilation
ATC03_00485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_00500	COG2197	response regulator
ATC03_00505	COG0386	Belongs to the glutathione peroxidase family
ATC03_00510	COG2195	Cleaves the N-terminal amino acid of tripeptides
ATC03_00520	COG3291	Pkd domain containing protein
ATC03_00520	COG4412	M6 family metalloprotease domain protein
ATC03_00545	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ATC03_00555	COG1063	alcohol dehydrogenase
ATC03_00560	COG0156	8-amino-7-oxononanoate synthase activity
ATC03_00565	COG4221	oxidoreductase activity
ATC03_00580	COG0534	Mate efflux family protein
ATC03_00585	COG3304	Inner membrane component domain
ATC03_00600	COG3590	peptidase
ATC03_00625	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATC03_00630	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ATC03_00635	COG0423	glycine-tRNA ligase activity
ATC03_00640	COG0519	Catalyzes the synthesis of GMP from XMP
ATC03_00645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ATC03_00665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ATC03_00710	COG0181	hydroxymethylbilane synthase activity
ATC03_00720	COG0113	porphobilinogen synthase activity
ATC03_00725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ATC03_00730	COG0025	NhaP-type Na H and K H
ATC03_00750	COG0714	Associated with various cellular activities
ATC03_00770	COG0631	protein serine/threonine phosphatase activity
ATC03_00835	COG1280	lysine exporter protein (LysE YggA)
ATC03_00840	COG1024	Enoyl-CoA hydratase
ATC03_00850	COG2079	MmgE PrpD family protein
ATC03_00885	COG1733	regulation of RNA biosynthetic process
ATC03_00940	COG0189	ligase activity
ATC03_00940	COG4067	protein conserved in archaea
ATC03_00945	COG0569	domain protein
ATC03_00945	COG0189	ligase activity
ATC03_00955	COG1725	Transcriptional regulator
ATC03_00995	COG1414	Transcriptional regulator
ATC03_01015	COG3104	oligopeptide transport
ATC03_01020	COG1216	Glycosyl transferase, family 2
ATC03_01025	COG2340	Cysteine-rich secretory protein family
ATC03_01030	COG2814	Major facilitator Superfamily
ATC03_01040	COG1940	carbohydrate kinase activity
ATC03_01050	COG2211	Major facilitator Superfamily
ATC03_01055	COG3152	Membrane
ATC03_01095	COG2186	Transcriptional regulator
ATC03_01110	COG0693	protein deglycase activity
ATC03_01125	COG0667	Aldo Keto reductase
ATC03_01170	COG1070	Carbohydrate kinase
ATC03_01175	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_01175	COG3347	Dehydrogenase
ATC03_01185	COG4952	isomerase
ATC03_01195	COG1879	ABC-type sugar transport system periplasmic component
ATC03_01200	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_01205	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_01210	COG1129	ABC transporter
ATC03_01215	COG1609	Transcriptional regulator
ATC03_01220	COG1609	Transcriptional regulator
ATC03_01225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATC03_01270	COG0095	Lipoate-protein ligase
ATC03_01280	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ATC03_01295	COG2723	6-phospho-beta-galactosidase activity
ATC03_01300	COG0395	ABC-type sugar transport system, permease component
ATC03_01315	COG1876	peptidase activity
ATC03_01335	COG2733	membrane
ATC03_01340	COG0077	Prephenate dehydratase
ATC03_01350	COG1597	lipid kinase activity
ATC03_01355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ATC03_01360	COG0561	phosphatase activity
ATC03_01365	COG1316	TRANSCRIPTIONal
ATC03_01375	COG1316	TRANSCRIPTIONal
ATC03_01395	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ATC03_01415	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_01430	COG1609	Transcriptional regulator
ATC03_01440	COG1653	transport
ATC03_01445	COG4209	transmembrane transport
ATC03_01450	COG0395	ABC-type sugar transport system, permease component
ATC03_01465	COG1131	(ABC) transporter
ATC03_01485	COG2274	protein secretion by the type I secretion system
ATC03_01510	COG0730	response to heat
ATC03_01535	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ATC03_01545	COG0505	Belongs to the CarA family
ATC03_01550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ATC03_01580	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ATC03_01585	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ATC03_01590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ATC03_01610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATC03_01620	COG0569	domain protein
ATC03_01625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ATC03_01665	COG0017	Asparaginyl-tRNA synthetase
ATC03_01670	COG0406	alpha-ribazole phosphatase activity
ATC03_01675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATC03_01680	COG0785	Cytochrome C biogenesis protein
ATC03_01685	COG1333	cytochrome c biogenesis protein
ATC03_01690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ATC03_01710	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_01715	COG1410	methionine synthase
ATC03_01715	COG0646	methionine synthase
ATC03_01730	COG1129	ABC transporter
ATC03_01765	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ATC03_01770	COG2326	polyphosphate kinase activity
ATC03_01780	COG2226	methyltransferase
ATC03_01795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATC03_01810	COG1666	GTP binding
ATC03_01830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ATC03_01830	COG2755	lipolytic protein G-D-S-L family
ATC03_01840	COG0739	heme binding
ATC03_01850	COG0366	Alpha amylase catalytic
ATC03_01855	COG2182	Extracellular solute-binding protein
ATC03_01860	COG1175	transmembrane transport
ATC03_01865	COG3833	ABC-type maltose transport systems, permease component
ATC03_01870	COG0366	Alpha amylase catalytic
ATC03_01885	COG2197	response regulator
ATC03_01900	COG1222	aaa ATPase
ATC03_02000	COG4974	Belongs to the 'phage' integrase family
ATC03_02010	COG1002	Type II restriction enzyme, methylase subunits
ATC03_02085	COG0640	Transcriptional regulator
ATC03_02105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_02135	COG1937	Protein conserved in bacteria
ATC03_02140	COG2217	Heavy metal translocating P-type atpase
ATC03_02185	COG1595	DNA-templated transcription, initiation
ATC03_02230	COG1609	Transcriptional regulator
ATC03_02245	COG2160	L-arabinose isomerase activity
ATC03_02250	COG2017	converts alpha-aldose to the beta-anomer
ATC03_02260	COG1846	Transcriptional regulator
ATC03_02265	COG0028	Belongs to the TPP enzyme family
ATC03_02270	COG1349	DNA-binding transcription factor activity
ATC03_02290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ATC03_02315	COG2409	Drug exporters of the RND superfamily
ATC03_02320	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ATC03_02345	COG0438	transferase activity, transferring glycosyl groups
ATC03_02350	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ATC03_02375	COG1126	abc transporter atp-binding protein
ATC03_02445	COG0456	acetyltransferase
ATC03_02460	COG0477	Major facilitator Superfamily
ATC03_02495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_02505	COG4166	transmembrane transport
ATC03_02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_02570	COG4101	3-hydroxyanthranilate 3,4-dioxygenase activity
ATC03_02585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATC03_02590	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ATC03_02595	COG3971	2-oxopent-4-enoate hydratase activity
ATC03_02620	COG3842	ATPase activity
ATC03_02640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ATC03_02690	COG2030	dehydratase
ATC03_02700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ATC03_02720	COG2197	response regulator
ATC03_02730	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_02755	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ATC03_02760	COG2501	S4 domain
ATC03_02765	COG4941	Belongs to the sigma-70 factor family
ATC03_02795	COG0583	DNA-binding transcription factor activity
ATC03_02800	COG0436	Aminotransferase
ATC03_02820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ATC03_02845	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ATC03_02850	COG0081	regulation of translation
ATC03_02865	COG0531	amino acid
ATC03_02870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATC03_02875	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ATC03_02915	COG0765	amino acid transport
ATC03_02920	COG1126	abc transporter atp-binding protein
ATC03_02955	COG1733	regulation of RNA biosynthetic process
ATC03_02970	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_02980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATC03_03000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ATC03_03020	COG1335	isochorismatase
ATC03_03025	COG1733	regulation of RNA biosynthetic process
ATC03_03030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ATC03_03040	COG1177	transmembrane transport
ATC03_03045	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATC03_03055	COG3842	ATPase activity
ATC03_03095	COG0415	Belongs to the DNA photolyase family
ATC03_03155	COG0673	inositol 2-dehydrogenase activity
ATC03_03160	COG1129	ABC transporter
ATC03_03165	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_03215	COG1136	(ABC) transporter
ATC03_03235	COG0745	RESPONSE REGULATOR receiver
ATC03_03240	COG2205	protein histidine kinase activity
ATC03_03250	COG3291	Pkd domain containing protein
ATC03_03255	COG1082	Xylose isomerase domain protein TIM barrel
ATC03_03270	COG0477	Major facilitator Superfamily
ATC03_03300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ATC03_03305	COG0222	ribosome binding
ATC03_03325	COG1653	transport
ATC03_03330	COG0395	ABC-type sugar transport system, permease component
ATC03_03335	COG1175	transmembrane transport
ATC03_03345	COG2814	Major facilitator Superfamily
ATC03_03350	COG1609	Transcriptional regulator
ATC03_03355	COG1653	transport
ATC03_03360	COG1175	transmembrane transport
ATC03_03365	COG0395	ABC-type sugar transport system, permease component
ATC03_03370	COG1132	(ABC) transporter
ATC03_03375	COG0477	Major facilitator Superfamily
ATC03_03410	COG1609	Transcriptional regulator
ATC03_03420	COG4213	ABC transporter substrate-binding protein
ATC03_03425	COG1129	ABC transporter
ATC03_03430	COG1172	Belongs to the binding-protein-dependent transport system permease family
ATC03_03475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATC03_03480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ATC03_03505	COG3345	alpha-galactosidase
ATC03_03510	COG1609	Transcriptional regulator
ATC03_03515	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_03520	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_03555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ATC03_03565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ATC03_03570	COG0531	amino acid
ATC03_03575	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_03660	COG3973	AAA domain
ATC03_03670	COG0477	Major facilitator Superfamily
ATC03_03710	COG1609	Transcriptional regulator
ATC03_03720	COG1653	transport
ATC03_03730	COG0395	ABC-type sugar transport system, permease component
ATC03_03755	COG2197	response regulator
ATC03_03760	COG3850	Histidine kinase
ATC03_03770	COG1136	(ABC) transporter
ATC03_03785	COG2814	Major facilitator Superfamily
ATC03_03790	COG0598	Magnesium transport protein CorA
ATC03_03820	COG2161	toxin-antitoxin pair type II binding
ATC03_03825	COG4115	mRNA cleavage
ATC03_03855	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ATC03_03875	COG1846	Transcriptional regulator
ATC03_03880	COG3250	beta-galactosidase activity
ATC03_03905	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_03935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ATC03_03940	COG0822	iron-sulfur transferase activity
ATC03_04005	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_04040	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_04060	COG3214	Protein conserved in bacteria
ATC03_04100	COG0456	acetyltransferase
ATC03_04105	COG1609	Transcriptional regulator
ATC03_04120	COG1653	transport
ATC03_04150	COG0640	Transcriptional regulator
ATC03_04165	COG0300	oxidoreductase activity
ATC03_04190	COG1595	DNA-templated transcription, initiation
ATC03_04200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ATC03_04215	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ATC03_04220	COG0251	oxidation-reduction process
ATC03_04225	COG4608	Belongs to the ABC transporter superfamily
ATC03_04230	COG4172	Belongs to the ABC transporter superfamily
ATC03_04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_04240	COG0601	transmembrane transport
ATC03_04285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ATC03_04295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ATC03_04310	COG0662	Cupin 2, conserved barrel domain protein
ATC03_04360	COG1595	DNA-templated transcription, initiation
ATC03_04370	COG0596	Alpha beta hydrolase
ATC03_04385	COG4585	Histidine kinase
ATC03_04390	COG2197	response regulator
ATC03_04410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATC03_04415	COG1253	flavin adenine dinucleotide binding
ATC03_04435	COG2205	protein histidine kinase activity
ATC03_04440	COG0745	RESPONSE REGULATOR receiver
ATC03_04480	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_04490	COG0492	ferredoxin-NADP+ reductase activity
ATC03_04510	COG1280	lysine exporter protein (LysE YggA)
ATC03_04525	COG0686	Belongs to the AlaDH PNT family
ATC03_04530	COG1609	Transcriptional regulator
ATC03_04535	COG1621	beta-fructofuranosidase activity
ATC03_04555	COG1621	beta-fructofuranosidase activity
ATC03_04565	COG1609	Transcriptional regulator
ATC03_04595	COG1175	transmembrane transport
ATC03_04610	COG1621	beta-fructofuranosidase activity
ATC03_04615	COG1621	beta-fructofuranosidase activity
ATC03_04620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATC03_04630	COG0542	response to heat
ATC03_04635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ATC03_04680	COG1653	transport
ATC03_04725	COG2197	response regulator
ATC03_04730	COG4585	Histidine kinase
ATC03_04760	COG3119	arylsulfatase activity
ATC03_04775	COG3250	beta-galactosidase activity
ATC03_04810	COG0494	nUDIX hydrolase
ATC03_04845	COG4702	Belongs to the UPF0303 family
ATC03_04850	COG1793	dna ligase
ATC03_04855	COG0406	alpha-ribazole phosphatase activity
ATC03_04925	COG0477	Major facilitator Superfamily
ATC03_04935	COG0659	secondary active sulfate transmembrane transporter activity
ATC03_04940	COG4552	Acetyltransferase involved in intracellular survival and related
ATC03_04945	COG1132	(ABC) transporter
ATC03_04960	COG0673	inositol 2-dehydrogenase activity
ATC03_04965	COG1609	Transcriptional regulator
ATC03_04970	COG0673	inositol 2-dehydrogenase activity
ATC03_04980	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_04995	COG1609	Transcriptional regulator
ATC03_05015	COG0673	inositol 2-dehydrogenase activity
ATC03_05030	COG1175	transmembrane transport
ATC03_05035	COG0395	ABC-type sugar transport system, permease component
ATC03_05060	COG1929	Belongs to the glycerate kinase type-1 family
ATC03_05075	COG4214	carbohydrate transport
ATC03_05090	COG1070	Carbohydrate kinase
ATC03_05095	COG2115	Belongs to the xylose isomerase family
ATC03_05100	COG1609	Transcriptional regulator
ATC03_05105	COG3507	Belongs to the glycosyl hydrolase 43 family
ATC03_05115	COG0395	ABC-type sugar transport system, permease component
ATC03_05125	COG1653	transport
ATC03_05135	COG1309	transcriptional regulator
ATC03_05145	COG2814	Major facilitator Superfamily
ATC03_05170	COG0395	ABC-type sugar transport system, permease component
ATC03_05180	COG0277	FAD linked oxidase domain protein
ATC03_05210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ATC03_05215	COG0590	tRNA wobble adenosine to inosine editing
ATC03_05220	COG2252	PERMEase
ATC03_05235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ATC03_05265	COG3257	ureidoglycine aminohydrolase activity
ATC03_05270	COG3622	Belongs to the hyi family
ATC03_05275	COG2084	Dehydrogenase
ATC03_05280	COG3960	tartronate-semialdehyde synthase activity
ATC03_05325	COG0433	COG0433 Predicted ATPase
ATC03_05365	COG2072	flavoprotein involved in K transport
ATC03_05375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ATC03_05390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ATC03_05400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ATC03_05415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ATC03_05435	COG5002	protein histidine kinase activity
ATC03_05475	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ATC03_05490	COG0800	Aldolase
ATC03_05495	COG0747	negative chemotaxis
ATC03_05500	COG0601	transmembrane transport
ATC03_05510	COG0444	Belongs to the ABC transporter superfamily
ATC03_05515	COG4608	Belongs to the ABC transporter superfamily
ATC03_05525	COG1486	melibiose metabolic process
ATC03_05535	COG0579	oxidoreductase
ATC03_05540	COG0488	(ABC) transporter
ATC03_05575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_05590	COG0438	transferase activity, transferring glycosyl groups
ATC03_05650	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ATC03_05655	COG1404	Belongs to the peptidase S8 family
ATC03_05700	COG2244	polysaccharide biosynthetic process
ATC03_05730	COG0438	transferase activity, transferring glycosyl groups
ATC03_05745	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_05760	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_05760	COG0300	oxidoreductase activity
ATC03_05760	COG3321	synthase
ATC03_05760	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_05760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ATC03_05775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ATC03_05805	COG0045	succinate-CoA ligase (ADP-forming) activity
ATC03_05830	COG0138	bifunctional purine biosynthesis protein purh
ATC03_05840	COG1834	amidinotransferase
ATC03_05845	COG1136	(ABC) transporter
ATC03_05845	COG0577	efflux transmembrane transporter activity
ATC03_05875	COG1132	(ABC) transporter
ATC03_05880	COG0019	diaminopimelate decarboxylase activity
ATC03_05890	COG2197	response regulator
ATC03_05895	COG4585	Histidine kinase
ATC03_05910	COG0538	isocitrate dehydrogenase activity
ATC03_05915	COG1940	carbohydrate kinase activity
ATC03_05925	COG1175	transmembrane transport
ATC03_05935	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_05975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ATC03_05980	COG1349	DNA-binding transcription factor activity
ATC03_05985	COG0191	fructose-bisphosphate aldolase activity
ATC03_06000	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATC03_06015	COG0395	ABC-type sugar transport system, permease component
ATC03_06020	COG1940	carbohydrate kinase activity
ATC03_06035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ATC03_06040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ATC03_06050	COG2089	acid synthase
ATC03_06075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ATC03_06080	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ATC03_06090	COG1349	DNA-binding transcription factor activity
ATC03_06095	COG2017	converts alpha-aldose to the beta-anomer
ATC03_06105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_06145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ATC03_06170	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ATC03_06175	COG0745	RESPONSE REGULATOR receiver
ATC03_06185	COG3485	protocatechuate 3,4-dioxygenase
ATC03_06200	COG0588	phosphoglycerate mutase activity
ATC03_06210	COG5002	protein histidine kinase activity
ATC03_06215	COG0745	RESPONSE REGULATOR receiver
ATC03_06230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ATC03_06230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ATC03_06235	COG0215	cysteine-tRNA ligase activity
ATC03_06250	COG3842	ATPase activity
ATC03_06275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATC03_06290	COG1278	Cold shock
ATC03_06295	COG1470	cell adhesion involved in biofilm formation
ATC03_06300	COG0459	protein refolding
ATC03_06310	COG5002	protein histidine kinase activity
ATC03_06315	COG0745	RESPONSE REGULATOR receiver
ATC03_06325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATC03_06335	COG1061	Type III restriction enzyme res subunit
ATC03_06350	COG1278	Cold shock
ATC03_06365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ATC03_06375	COG1388	LysM domain
ATC03_06375	COG3103	Sh3 type 3 domain protein
ATC03_06375	COG0791	NLP P60 protein
ATC03_06385	COG1388	LysM domain
ATC03_06385	COG3942	CHAP domain
ATC03_06410	COG1793	dna ligase
ATC03_06415	COG1522	sequence-specific DNA binding
ATC03_06420	COG0686	Belongs to the AlaDH PNT family
ATC03_06425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ATC03_06425	COG0425	Belongs to the sulfur carrier protein TusA family
ATC03_06435	COG1970	mechanosensitive ion channel activity
ATC03_06450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ATC03_06480	COG2814	Major facilitator Superfamily
ATC03_06500	COG0475	glutathione-regulated potassium exporter activity
ATC03_06525	COG0656	L-ascorbic acid biosynthetic process
ATC03_06540	COG2233	PERMEase
ATC03_06545	COG1643	Atp-dependent helicase
ATC03_06555	COG1331	Highly conserved protein containing a thioredoxin domain
ATC03_06560	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ATC03_06595	COG0484	heat shock protein binding
ATC03_06600	COG1362	aminopeptidase activity
ATC03_06610	COG1760	l-serine dehydratase
ATC03_06650	COG1131	(ABC) transporter
ATC03_06660	COG3548	integral membrane protein
ATC03_06665	COG1832	CoA-binding protein
ATC03_06675	COG2329	Antibiotic biosynthesis monooxygenase
ATC03_06680	COG2076	Multidrug Resistance protein
ATC03_06690	COG1476	TRANSCRIPTIONal
ATC03_06710	COG2855	membrane
ATC03_06730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATC03_06735	COG0084	hydrolase, TatD family'
ATC03_06740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ATC03_06745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ATC03_06750	COG0488	(ABC) transporter
ATC03_06760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ATC03_06765	COG2011	ABC-type metal ion transport system permease component
ATC03_06785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATC03_06790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ATC03_06795	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_06815	COG2149	membrane
ATC03_06820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ATC03_06825	COG2084	Dehydrogenase
ATC03_06835	COG1414	Transcriptional regulator
ATC03_06840	COG0477	Major facilitator Superfamily
ATC03_06845	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_06855	COG1063	alcohol dehydrogenase
ATC03_06860	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ATC03_06865	COG0193	aminoacyl-tRNA hydrolase activity
ATC03_06870	COG2860	membrane
ATC03_06890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATC03_06895	COG1280	lysine exporter protein (LysE YggA)
ATC03_06905	COG0124	histidyl-tRNA synthetase
ATC03_06910	COG0148	phosphopyruvate hydratase activity
ATC03_06925	COG1404	Belongs to the peptidase S8 family
ATC03_06955	COG0248	Ppx GppA phosphatase
ATC03_06990	COG1704	LemA family
ATC03_06995	COG0501	Belongs to the peptidase M48B family
ATC03_07000	COG3214	Protein conserved in bacteria
ATC03_07010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ATC03_07015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ATC03_07035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ATC03_07045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ATC03_07055	COG0114	fumarate hydratase activity
ATC03_07080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ATC03_07090	COG0191	fructose-bisphosphate aldolase activity
ATC03_07095	COG1494	fructose-1,6-bisphosphatase
ATC03_07155	COG0012	GTP binding
ATC03_07200	COG0488	(ABC) transporter
ATC03_07215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATC03_07230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATC03_07265	COG2814	Major facilitator Superfamily
ATC03_07270	COG1104	cysteine desulfurase activity
ATC03_07285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ATC03_07295	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ATC03_07300	COG0509	glycine decarboxylation via glycine cleavage system
ATC03_07305	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATC03_07305	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ATC03_07320	COG4166	transmembrane transport
ATC03_07345	COG0739	heme binding
ATC03_07350	COG1024	Enoyl-CoA hydratase
ATC03_07385	COG2171	N-acyltransferase activity
ATC03_07390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_07405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATC03_07440	COG2239	Acts as a magnesium transporter
ATC03_07455	COG0006	proline dipeptidase activity
ATC03_07465	COG0613	PHP domain protein
ATC03_07470	COG0513	Belongs to the DEAD box helicase family
ATC03_07495	COG0210	DNA helicase
ATC03_07520	COG3480	Lon protease (S16) C-terminal proteolytic domain
ATC03_07525	COG1615	UPF0182 protein
ATC03_07570	COG0596	Alpha beta hydrolase
ATC03_07575	COG0628	permease
ATC03_07585	COG3973	AAA domain
ATC03_07590	COG4221	oxidoreductase activity
ATC03_07605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ATC03_07615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ATC03_07620	COG1215	transferase activity, transferring glycosyl groups
ATC03_07660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ATC03_07685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ATC03_07690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ATC03_07695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ATC03_07705	COG0586	Pfam SNARE associated Golgi protein
ATC03_07760	COG1609	Transcriptional regulator
ATC03_07765	COG1063	alcohol dehydrogenase
ATC03_07815	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATC03_07825	COG1228	amidohydrolase
ATC03_07835	COG2884	Cell division ATP-binding protein ftsE
ATC03_07845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ATC03_07865	COG3537	Alpha-1,2-mannosidase
ATC03_07900	COG0483	inositol monophosphate 1-phosphatase activity
ATC03_07975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ATC03_07990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ATC03_07995	COG1122	ATPase activity
ATC03_08000	COG0183	Belongs to the thiolase family
ATC03_08005	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_08010	COG1268	BioY protein
ATC03_08030	COG0129	dihydroxy-acid dehydratase activity
ATC03_08035	COG0028	Belongs to the TPP enzyme family
ATC03_08040	COG0440	acetolactate synthase activity
ATC03_08045	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ATC03_08080	COG3142	Participates in the control of copper homeostasis
ATC03_08105	COG0477	Major facilitator Superfamily
ATC03_08115	COG0473	3-isopropylmalate dehydrogenase activity
ATC03_08120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ATC03_08125	COG0456	acetyltransferase
ATC03_08130	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_08140	COG0583	DNA-binding transcription factor activity
ATC03_08145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ATC03_08165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ATC03_08195	COG0861	Integral membrane protein TerC family
ATC03_08200	COG0631	protein serine/threonine phosphatase activity
ATC03_08210	COG2815	serine threonine protein kinase
ATC03_08210	COG0515	serine threonine protein kinase
ATC03_08225	COG0714	Associated with various cellular activities
ATC03_08245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ATC03_08250	COG0066	3-isopropylmalate dehydratase activity
ATC03_08255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ATC03_08260	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_08260	COG0204	Acyl-transferase
ATC03_08265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ATC03_08270	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATC03_08290	COG0742	ribosomal rna small subunit methyltransferase
ATC03_08300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ATC03_08305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ATC03_08310	COG0714	Associated with various cellular activities
ATC03_08330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ATC03_08335	COG0571	ribonuclease III activity
ATC03_08340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ATC03_08350	COG1196	nuclear chromosome segregation
ATC03_08390	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ATC03_08395	COG0228	four-way junction DNA binding
ATC03_08400	COG1837	Belongs to the UPF0109 family
ATC03_08405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ATC03_08410	COG0336	Belongs to the RNA methyltransferase TrmD family
ATC03_08420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATC03_08425	COG0243	molybdopterin cofactor binding
ATC03_08430	COG2223	nitrite transmembrane transporter activity
ATC03_08445	COG2146	nitrite reductase [NAD(P)H] activity
ATC03_08445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATC03_08465	COG0335	large ribosomal subunit rRNA binding
ATC03_08470	COG0681	Belongs to the peptidase S26 family
ATC03_08475	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ATC03_08485	COG0792	nuclease activity
ATC03_08490	COG0606	chelatase, subunit chli
ATC03_08505	COG4974	Belongs to the 'phage' integrase family
ATC03_08515	COG0052	Belongs to the universal ribosomal protein uS2 family
ATC03_08520	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ATC03_08525	COG0528	UMP kinase activity
ATC03_08530	COG0233	cytoplasmic translational termination
ATC03_08580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ATC03_08585	COG0366	Alpha amylase catalytic
ATC03_08590	COG0058	SHG alpha-glucan phosphorylase activity
ATC03_08610	COG0482	sulfurtransferase activity
ATC03_08625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ATC03_08635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATC03_08640	COG0154	amidase activity
ATC03_08645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ATC03_08665	COG4721	ABC-type cobalt transport system, permease component
ATC03_08670	COG1122	ATPase activity
ATC03_08985	COG0582	viral genome integration into host DNA
ATC03_08995	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ATC03_09005	COG0569	domain protein
ATC03_09005	COG0475	glutathione-regulated potassium exporter activity
ATC03_09010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ATC03_09020	COG0667	Aldo Keto reductase
ATC03_09055	COG1946	Acyl-CoA thioesterase
ATC03_09075	COG0668	transmembrane transport
ATC03_09085	COG2197	response regulator
ATC03_09090	COG4585	Histidine kinase
ATC03_09130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ATC03_09135	COG2132	Multicopper oxidase
ATC03_09155	COG0783	Belongs to the Dps family
ATC03_09170	COG0544	peptidyl-prolyl cis-trans isomerase activity
ATC03_09180	COG0740	serine-type endopeptidase activity
ATC03_09185	COG0740	serine-type endopeptidase activity
ATC03_09190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ATC03_09195	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ATC03_09200	COG3135	benzoate transporter
ATC03_09220	COG0756	dUTP diphosphatase activity
ATC03_09235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ATC03_09240	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ATC03_09245	COG1024	Enoyl-CoA hydratase
ATC03_09245	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATC03_09250	COG0183	Belongs to the thiolase family
ATC03_09255	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ATC03_09325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ATC03_09335	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ATC03_09345	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ATC03_09350	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ATC03_09360	COG0217	transcriptional regulatory protein
ATC03_09365	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ATC03_09370	COG0632	four-way junction helicase activity
ATC03_09375	COG2255	four-way junction helicase activity
ATC03_09385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATC03_09390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ATC03_09395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ATC03_09420	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ATC03_09430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATC03_09435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ATC03_09445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ATC03_09450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ATC03_09455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ATC03_09460	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ATC03_09465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ATC03_09470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ATC03_09475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ATC03_09490	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ATC03_09495	COG0540	Belongs to the ATCase OTCase family
ATC03_09500	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_09510	COG0505	Belongs to the CarA family
ATC03_09515	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ATC03_09520	COG0284	orotidine-5'-phosphate decarboxylase activity
ATC03_09525	COG0194	GDP metabolic process
ATC03_09530	COG1758	RNA polymerase activity
ATC03_09540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ATC03_09550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ATC03_09560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ATC03_09565	COG0140	phosphoribosyl-ATP diphosphatase activity
ATC03_09570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ATC03_09575	COG0107	imidazoleglycerol-phosphate synthase activity
ATC03_09580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ATC03_09600	COG0134	indole-3-glycerol-phosphate synthase activity
ATC03_09605	COG0133	tryptophan synthase activity
ATC03_09610	COG0159	tryptophan synthase activity
ATC03_09615	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ATC03_09620	COG0067	glutamate synthase
ATC03_09620	COG0069	glutamate synthase activity
ATC03_09620	COG0070	glutamate synthase
ATC03_09660	COG0539	negative regulation of cytoplasmic translation
ATC03_09665	COG0237	dephospho-CoA kinase activity
ATC03_09670	COG0556	nucleotide-excision repair
ATC03_09680	COG0322	excinuclease ABC activity
ATC03_09685	COG1660	Displays ATPase and GTPase activities
ATC03_09690	COG1481	regulation of sporulation
ATC03_09695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ATC03_09705	COG0126	phosphoglycerate kinase activity
ATC03_09710	COG0149	triose-phosphate isomerase activity
ATC03_09715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ATC03_09725	COG0363	glucosamine-6-phosphate deaminase activity
ATC03_09740	COG0166	Belongs to the GPI family
ATC03_09745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ATC03_09755	COG0109	protoheme IX farnesyltransferase activity
ATC03_09765	COG1612	heme a metabolic process
ATC03_09785	COG0396	ATPase activity
ATC03_09790	COG2151	metal-sulfur cluster biosynthetic enzyme
ATC03_09795	COG0339	signal peptide processing
ATC03_09810	COG0525	valine-tRNA ligase activity
ATC03_09830	COG0747	negative chemotaxis
ATC03_09845	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ATC03_09850	COG0285	dihydrofolate synthase activity
ATC03_09860	COG0105	UTP biosynthetic process
ATC03_09880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ATC03_09885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ATC03_09890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ATC03_09895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ATC03_09900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ATC03_09910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ATC03_09920	COG0799	negative regulation of ribosome biogenesis
ATC03_09955	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_09960	COG2353	YceI-like domain
ATC03_09970	COG0488	(ABC) transporter
ATC03_09990	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_09995	COG0560	Phosphoserine phosphatase
ATC03_10000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ATC03_10005	COG0297	glycogen (starch) synthase activity
ATC03_10010	COG1119	ATPase activity
ATC03_10015	COG0254	rRNA binding
ATC03_10025	COG2267	carboxylic ester hydrolase activity
ATC03_10035	COG0406	alpha-ribazole phosphatase activity
ATC03_10065	COG2814	Major facilitator Superfamily
ATC03_10080	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_10090	COG0587	DNA-directed DNA polymerase activity
ATC03_10110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_10115	COG1968	undecaprenyl-diphosphatase activity
ATC03_10125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATC03_10135	COG0545	Peptidyl-prolyl cis-trans isomerase
ATC03_10150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATC03_10155	COG0805	protein transport
ATC03_10160	COG4581	dead DEAH box helicase
ATC03_10175	COG0584	glycerophosphoryl diester phosphodiesterase
ATC03_10190	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_10210	COG1396	sequence-specific DNA binding
ATC03_10230	COG1063	alcohol dehydrogenase
ATC03_10235	COG0640	Transcriptional regulator
ATC03_10240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATC03_10250	COG0471	metal ion transport
ATC03_10250	COG0490	domain, Protein
ATC03_10260	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_10270	COG1461	Dihydroxyacetone kinase
ATC03_10275	COG2376	Dihydroxyacetone kinase
ATC03_10280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_10285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATC03_10290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ATC03_10295	COG1845	cytochrome c oxidase, subunit III
ATC03_10300	COG2010	Cytochrome c
ATC03_10305	COG0723	plastoquinol--plastocyanin reductase activity
ATC03_10310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ATC03_10315	COG2226	methyltransferase
ATC03_10325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ATC03_10330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ATC03_10340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ATC03_10355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ATC03_10360	COG0187	DNA topoisomerase II activity
ATC03_10375	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATC03_10380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ATC03_10390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ATC03_10395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATC03_10400	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_10410	COG0321	lipoyl(octanoyl) transferase activity
ATC03_10415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ATC03_10430	COG0174	glutamine synthetase
ATC03_10435	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ATC03_10440	COG0174	glutamine synthetase
ATC03_10445	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ATC03_10475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ATC03_10490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ATC03_10505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ATC03_10510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ATC03_10515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ATC03_10550	COG2353	YceI-like domain
ATC03_10575	COG0783	Belongs to the Dps family
ATC03_10580	COG1063	alcohol dehydrogenase
ATC03_10650	COG1216	Glycosyl transferase, family 2
ATC03_10655	COG0583	DNA-binding transcription factor activity
ATC03_10670	COG1132	(ABC) transporter
ATC03_10680	COG0183	Belongs to the thiolase family
ATC03_10695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATC03_10705	COG3485	protocatechuate 3,4-dioxygenase
ATC03_10710	COG3485	protocatechuate 3,4-dioxygenase
ATC03_10725	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_10735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ATC03_10745	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_10755	COG2814	Major facilitator Superfamily
ATC03_10765	COG2197	response regulator
ATC03_10800	COG0410	ABC transporter
ATC03_10810	COG2124	cytochrome p450
ATC03_10835	COG0395	ABC-type sugar transport system, permease component
ATC03_10850	COG1609	Transcriptional regulator
ATC03_10885	COG2094	Belongs to the DNA glycosylase MPG family
ATC03_10890	COG2140	Oxalate decarboxylase
ATC03_10905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_10910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_10915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_10925	COG2197	response regulator
ATC03_10935	COG2837	iron assimilation
ATC03_10950	COG3189	MarR family transcriptional regulator
ATC03_10980	COG1122	ATPase activity
ATC03_11020	COG1024	Enoyl-CoA hydratase
ATC03_11025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATC03_11045	COG1472	Belongs to the glycosyl hydrolase 3 family
ATC03_11075	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_11080	COG0246	Mannitol dehydrogenase
ATC03_11085	COG1904	glucuronate isomerase
ATC03_11100	COG2211	Major facilitator Superfamily
ATC03_11100	COG2190	(PTS) system
ATC03_11120	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_11135	COG2814	Major facilitator Superfamily
ATC03_11215	COG0601	transmembrane transport
ATC03_11225	COG0358	DNA primase activity
ATC03_11240	COG0442	prolyl-tRNA aminoacylation
ATC03_11245	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATC03_11245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATC03_11270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ATC03_11275	COG1381	Involved in DNA repair and RecF pathway recombination
ATC03_11285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ATC03_11290	COG0577	efflux transmembrane transporter activity
ATC03_11295	COG1136	(ABC) transporter
ATC03_11300	COG2197	response regulator
ATC03_11305	COG4585	Histidine kinase
ATC03_11310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ATC03_11320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ATC03_11330	COG0537	adenosine 5'-monophosphoramidase activity
ATC03_11340	COG0484	heat shock protein binding
ATC03_11345	COG1420	regulation of RNA biosynthetic process
ATC03_11360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ATC03_11365	COG4762	Protein conserved in bacteria
ATC03_11370	COG0481	GTPase activity
ATC03_11375	COG4585	Histidine kinase
ATC03_11380	COG2197	response regulator
ATC03_11385	COG0268	Binds directly to 16S ribosomal RNA
ATC03_11405	COG0495	leucyl-tRNA aminoacylation
ATC03_11410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ATC03_11410	COG0512	Glutamine amidotransferase of anthranilate synthase
ATC03_11415	COG1132	(ABC) transporter
ATC03_11425	COG1294	oxidase, subunit
ATC03_11430	COG1271	oxidase subunit
ATC03_11440	COG0501	Belongs to the peptidase M48B family
ATC03_11445	COG0586	Pfam SNARE associated Golgi protein
ATC03_11460	COG1174	glycine betaine transport
ATC03_11465	COG0517	IMP dehydrogenase activity
ATC03_11465	COG1125	glycine betaine transport
ATC03_11480	COG0167	dihydroorotate dehydrogenase activity
ATC03_11485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ATC03_11490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ATC03_11495	COG0587	DNA-directed DNA polymerase activity
ATC03_11510	COG3599	regulation of cell shape
ATC03_11520	COG1799	cell septum assembly
ATC03_11525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ATC03_11530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ATC03_11540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ATC03_11545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ATC03_11550	COG0772	Belongs to the SEDS family
ATC03_11555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ATC03_11560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ATC03_11570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ATC03_11585	COG0275	rRNA processing
ATC03_11590	COG2001	Belongs to the MraZ family
ATC03_11600	COG0142	geranyltranstransferase activity
ATC03_11610	COG1388	LysM domain
ATC03_11610	COG3942	CHAP domain
ATC03_11615	COG2815	serine threonine protein kinase
ATC03_11615	COG0515	serine threonine protein kinase
ATC03_11620	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ATC03_11630	COG1940	carbohydrate kinase activity
ATC03_11650	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ATC03_11655	COG1192	Involved in chromosome partitioning
ATC03_11745	COG3012	SEC-C Motif Domain Protein
ATC03_11755	COG2357	RelA SpoT domain protein
ATC03_11780	COG0204	Acyl-transferase
ATC03_11800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATC03_11805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ATC03_11830	COG0385	Bile acid
ATC03_11845	COG1695	Transcriptional regulator
ATC03_11850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ATC03_11875	COG2205	protein histidine kinase activity
ATC03_11880	COG0745	RESPONSE REGULATOR receiver
ATC03_11900	COG0531	amino acid
ATC03_11905	COG1917	Cupin 2, conserved barrel domain protein
ATC03_11905	COG1396	sequence-specific DNA binding
ATC03_11920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATC03_11975	COG0785	Cytochrome C biogenesis protein
ATC03_11980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATC03_11985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ATC03_11985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ATC03_11990	COG0739	heme binding
ATC03_12020	COG2837	iron assimilation
ATC03_12025	COG2847	Copper chaperone PCu(A)C
ATC03_12040	COG0789	Transcriptional regulator
ATC03_12155	COG1937	Protein conserved in bacteria
ATC03_12160	COG2217	Heavy metal translocating P-type atpase
ATC03_12170	COG2217	Heavy metal translocating P-type atpase
ATC03_12245	COG1388	LysM domain
ATC03_12245	COG4942	peptidase
ATC03_12335	COG1160	GTP binding
ATC03_12340	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ATC03_12355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ATC03_12360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ATC03_12380	COG0504	CTP synthase activity
ATC03_12385	COG0497	DNA recombination
ATC03_12390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ATC03_12400	COG0647	UMP catabolic process
ATC03_12425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ATC03_12440	COG2094	Belongs to the DNA glycosylase MPG family
ATC03_12445	COG0165	Argininosuccinate lyase
ATC03_12460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ATC03_12465	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ATC03_12470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ATC03_12480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_12490	COG4166	transmembrane transport
ATC03_12495	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ATC03_12510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ATC03_12510	COG0072	phenylalanine-tRNA ligase activity
ATC03_12515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ATC03_12520	COG0765	amino acid transport
ATC03_12525	COG0765	amino acid transport
ATC03_12535	COG1126	abc transporter atp-binding protein
ATC03_12540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ATC03_12545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ATC03_12550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ATC03_12555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ATC03_12570	COG1201	RNA secondary structure unwinding
ATC03_12585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ATC03_12590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ATC03_12595	COG0131	Imidazoleglycerol-phosphate dehydratase
ATC03_12600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATC03_12610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ATC03_12620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ATC03_12625	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ATC03_12630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ATC03_12635	COG2890	protein-(glutamine-N5) methyltransferase activity
ATC03_12640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ATC03_12645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ATC03_12650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ATC03_12660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ATC03_12670	COG1396	sequence-specific DNA binding
ATC03_12675	COG1546	Belongs to the CinA family
ATC03_12675	COG1058	Belongs to the CinA family
ATC03_12685	COG1674	ftsk spoiiie
ATC03_12695	COG0577	efflux transmembrane transporter activity
ATC03_12710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ATC03_12715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ATC03_12730	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ATC03_12745	COG1764	response to oxidative stress
ATC03_12750	COG1090	epimerase
ATC03_12760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ATC03_12775	COG0612	Peptidase, M16
ATC03_12780	COG0667	Aldo Keto reductase
ATC03_12795	COG1960	acyl-CoA dehydrogenase activity
ATC03_12805	COG2226	methyltransferase
ATC03_12830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ATC03_12845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATC03_12850	COG1309	transcriptional regulator
ATC03_12860	COG2154	pterin-4-alpha-carbinolamine dehydratase
ATC03_12865	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_12870	COG0022	dehydrogenase e1 component
ATC03_12900	COG2755	lipolytic protein G-D-S-L family
ATC03_12905	COG1185	polyribonucleotide nucleotidyltransferase activity
ATC03_12920	COG1131	(ABC) transporter
ATC03_12925	COG3559	Exporter of polyketide antibiotics
ATC03_12950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_12960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ATC03_12990	COG2826	transposase and inactivated derivatives, IS30 family
ATC03_13015	COG1573	uracil-dna glycosylase
ATC03_13020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ATC03_13030	COG3189	MarR family transcriptional regulator
ATC03_13070	COG0545	Peptidyl-prolyl cis-trans isomerase
ATC03_13090	COG2186	Transcriptional regulator
ATC03_13120	COG2186	Transcriptional regulator
ATC03_13125	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_13145	COG2233	PERMEase
ATC03_13150	COG2252	PERMEase
ATC03_13165	COG1051	belongs to the nudix hydrolase family
ATC03_13175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATC03_13190	COG1937	Protein conserved in bacteria
ATC03_13200	COG0702	epimerase
ATC03_13210	COG3177	Filamentation induced by cAMP protein fic
ATC03_13225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ATC03_13230	COG2390	Transcriptional regulator
ATC03_13235	COG1940	carbohydrate kinase activity
ATC03_13240	COG2807	transmembrane transport
ATC03_13245	COG0196	riboflavin kinase activity
ATC03_13260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ATC03_13265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ATC03_13285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ATC03_13290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ATC03_13305	COG0442	prolyl-tRNA aminoacylation
ATC03_13325	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ATC03_13340	COG0183	Belongs to the thiolase family
ATC03_13355	COG2197	response regulator
ATC03_13360	COG4585	Histidine kinase
ATC03_13365	COG0750	zinc metalloprotease
ATC03_13370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ATC03_13380	COG0204	Acyl-transferase
ATC03_13380	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_13410	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATC03_13415	COG3842	ATPase activity
ATC03_13425	COG1674	ftsk spoiiie
ATC03_13445	COG0714	Associated with various cellular activities
ATC03_13460	COG0631	protein serine/threonine phosphatase activity
ATC03_13475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ATC03_13480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATC03_13490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATC03_13500	COG3022	response to hydroperoxide
ATC03_13510	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ATC03_13515	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ATC03_13520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ATC03_13525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ATC03_13530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATC03_13535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ATC03_13540	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ATC03_13545	COG0356	it plays a direct role in the translocation of protons across the membrane
ATC03_13580	COG2890	protein-(glutamine-N5) methyltransferase activity
ATC03_13590	COG1045	serine acetyltransferase
ATC03_13595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ATC03_13605	COG0083	homoserine kinase activity
ATC03_13610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ATC03_13615	COG0460	homoserine dehydrogenase
ATC03_13620	COG0019	diaminopimelate decarboxylase activity
ATC03_13630	COG0018	arginyl-trna synthetase
ATC03_13640	COG1846	Transcriptional regulator
ATC03_13640	COG1940	carbohydrate kinase activity
ATC03_13665	COG1842	Phage shock protein A
ATC03_13690	COG1120	ATPase activity
ATC03_13695	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_13700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_13710	COG0154	amidase activity
ATC03_13735	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ATC03_13740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ATC03_13760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ATC03_13780	COG2814	Major facilitator Superfamily
ATC03_13810	COG0765	amino acid transport
ATC03_13820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ATC03_13825	COG1011	Hydrolase
ATC03_13830	COG1902	pentaerythritol trinitrate reductase activity
ATC03_13855	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_13855	COG0567	Dehydrogenase, E1 component
ATC03_13870	COG1595	DNA-templated transcription, initiation
ATC03_13930	COG0653	protein targeting
ATC03_13935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ATC03_13940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATC03_13945	COG5401	PFAM Sporulation and spore germination
ATC03_13955	COG0745	RESPONSE REGULATOR receiver
ATC03_13975	COG0714	Associated with various cellular activities
ATC03_13985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_14000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ATC03_14005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATC03_14045	COG1482	cell wall glycoprotein biosynthetic process
ATC03_14050	COG1960	acyl-CoA dehydrogenase activity
ATC03_14100	COG1216	Glycosyl transferase, family 2
ATC03_14120	COG1086	Polysaccharide biosynthesis protein
ATC03_14130	COG1216	Glycosyl transferase, family 2
ATC03_14145	COG1216	Glycosyl transferase, family 2
ATC03_14150	COG0463	Glycosyl transferase, family 2
ATC03_14165	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ATC03_14170	COG1088	dTDP-glucose 4,6-dehydratase activity
ATC03_14200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATC03_14200	COG0546	phosphoglycolate phosphatase activity
ATC03_14205	COG0297	glycogen (starch) synthase activity
ATC03_14215	COG0297	glycogen (starch) synthase activity
ATC03_14290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ATC03_14315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ATC03_14320	COG0424	maF-like protein
ATC03_14325	COG4770	biotin carboxylase activity
ATC03_14335	COG0531	amino acid
ATC03_14350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATC03_14360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ATC03_14365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ATC03_14395	COG1744	ABC transporter substrate-binding protein PnrA-like
ATC03_14400	COG1744	ABC transporter substrate-binding protein PnrA-like
ATC03_14410	COG2009	succinate dehydrogenase
ATC03_14425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ATC03_14445	COG0708	Exodeoxyribonuclease III
ATC03_14450	COG0180	Tryptophanyl-tRNA synthetase
ATC03_14465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ATC03_14470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ATC03_14480	COG2390	Transcriptional regulator
ATC03_14495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ATC03_14495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ATC03_14500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ATC03_14510	COG0477	Major facilitator Superfamily
ATC03_14525	COG2313	pseudouridylate synthase activity
ATC03_14540	COG1132	(ABC) transporter
ATC03_14555	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ATC03_14580	COG0183	Belongs to the thiolase family
ATC03_14630	COG3971	2-oxopent-4-enoate hydratase activity
ATC03_14640	COG0179	Fumarylacetoacetate (FAA) hydrolase
ATC03_14650	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_14665	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_14670	COG1309	transcriptional regulator
ATC03_14695	COG1335	isochorismatase
ATC03_14705	COG0673	inositol 2-dehydrogenase activity
ATC03_14725	COG1309	transcriptional regulator
ATC03_14730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ATC03_14735	COG1653	transport
ATC03_14740	COG0395	ABC-type sugar transport system, permease component
ATC03_14745	COG1175	transmembrane transport
ATC03_14750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ATC03_14760	COG1414	Transcriptional regulator
ATC03_14780	COG3833	ABC-type maltose transport systems, permease component
ATC03_14785	COG1175	transmembrane transport
ATC03_14810	COG3250	beta-galactosidase activity
ATC03_14825	COG0577	efflux transmembrane transporter activity
ATC03_14825	COG1136	(ABC) transporter
ATC03_14830	COG1136	(ABC) transporter
ATC03_14830	COG0577	efflux transmembrane transporter activity
ATC03_14845	COG0745	RESPONSE REGULATOR receiver
ATC03_14850	COG2205	protein histidine kinase activity
ATC03_14870	COG4948	Mandelate Racemase Muconate Lactonizing
ATC03_14900	COG0800	Aldolase
ATC03_14915	COG2197	response regulator
ATC03_14935	COG0470	DNA polymerase III
ATC03_14940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ATC03_14945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ATC03_14945	COG1754	DNA topoisomerase type I activity
ATC03_14985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ATC03_14990	COG0584	glycerophosphoryl diester phosphodiesterase
ATC03_15000	COG0039	L-malate dehydrogenase activity
ATC03_15005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATC03_15005	COG0519	Catalyzes the synthesis of GMP from XMP
ATC03_15015	COG1309	transcriptional regulator
ATC03_15030	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ATC03_15035	COG0516	GMP reductase activity
ATC03_15040	COG0488	(ABC) transporter
ATC03_15045	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ATC03_15085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ATC03_15110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ATC03_15115	COG0456	acetyltransferase
ATC03_15125	COG0802	atpase or kinase
ATC03_15130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ATC03_15135	COG0736	holo-[acyl-carrier-protein] synthase activity
ATC03_15140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ATC03_15145	COG1072	(Pantothenic acid kinase))
ATC03_15150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ATC03_15155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ATC03_15160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ATC03_15165	COG0101	tRNA pseudouridine synthase activity
ATC03_15170	COG0203	ribosomal protein L17
ATC03_15175	COG0202	RNA polymerase activity
ATC03_15180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ATC03_15185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ATC03_15190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ATC03_15195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ATC03_15200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ATC03_15205	COG0024	Methionine aminopeptidase
ATC03_15210	COG0563	adenylate kinase activity
ATC03_15220	COG0200	Binds to the 23S rRNA
ATC03_15225	COG1841	ribosomal large subunit assembly
ATC03_15230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ATC03_15235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ATC03_15240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ATC03_15245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ATC03_15250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ATC03_15255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ATC03_15260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ATC03_15265	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ATC03_15270	COG0255	Belongs to the universal ribosomal protein uL29 family
ATC03_15275	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ATC03_15280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ATC03_15285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ATC03_15290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ATC03_15295	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ATC03_15300	COG0089	rRNA binding
ATC03_15305	COG0088	Forms part of the polypeptide exit tunnel
ATC03_15310	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ATC03_15315	COG0051	transcription antitermination factor activity, RNA binding
ATC03_15330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ATC03_15335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ATC03_15340	COG0049	tRNA binding
ATC03_15345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ATC03_15355	COG1739	Uncharacterized protein family UPF0029
ATC03_15450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ATC03_15485	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ATC03_15490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ATC03_15495	COG0085	RNA polymerase activity
ATC03_15515	COG1984	allophanate hydrolase subunit 2
ATC03_15525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ATC03_15565	COG0513	Belongs to the DEAD box helicase family
ATC03_15625	COG0519	Catalyzes the synthesis of GMP from XMP
ATC03_15625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ATC03_15640	COG2261	transglycosylase associated protein
ATC03_15650	COG3938	Belongs to the proline racemase family
ATC03_15670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ATC03_15675	COG2066	Belongs to the glutaminase family
ATC03_15675	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ATC03_15685	COG1802	Transcriptional regulator
ATC03_15690	COG0006	proline dipeptidase activity
ATC03_15705	COG0667	Aldo Keto reductase
ATC03_15735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ATC03_15750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ATC03_15760	COG0542	response to heat
ATC03_15770	COG3655	Transcriptional regulator
ATC03_15800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ATC03_15835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ATC03_15840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ATC03_15845	COG0302	gtp cyclohydrolase
ATC03_15850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ATC03_15860	COG0037	tRNA processing
ATC03_15865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ATC03_15875	COG1196	nuclear chromosome segregation
ATC03_15875	COG0739	heme binding
ATC03_15875	COG0741	lytic transglycosylase activity
ATC03_15895	COG0438	transferase activity, transferring glycosyl groups
ATC03_15900	COG0438	transferase activity, transferring glycosyl groups
ATC03_15920	COG2197	response regulator
ATC03_15925	COG3850	Histidine kinase
ATC03_15935	COG0534	Mate efflux family protein
ATC03_15975	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ATC03_15975	COG1796	DNA polymerase
ATC03_15990	COG0596	Alpha beta hydrolase
ATC03_16005	COG0039	L-malate dehydrogenase activity
ATC03_16045	COG1609	Transcriptional regulator
ATC03_16060	COG0395	ABC-type sugar transport system, permease component
ATC03_16080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ATC03_16095	COG0514	ATP-dependent DNA helicase (RecQ)
ATC03_16115	COG4085	toxin activity
ATC03_16115	COG1525	nuclease
ATC03_16115	COG0737	Belongs to the 5'-nucleotidase family
ATC03_16125	COG4581	dead DEAH box helicase
ATC03_16135	COG3265	gluconokinase activity
ATC03_16140	COG0738	Major facilitator superfamily
ATC03_16150	COG0667	Aldo Keto reductase
ATC03_16160	COG0384	phenazine biosynthesis protein PhzF
ATC03_16175	COG0640	Transcriptional regulator
ATC03_16185	COG1846	Transcriptional regulator
ATC03_16190	COG2814	Major facilitator Superfamily
ATC03_16195	COG0656	L-ascorbic acid biosynthetic process
ATC03_16200	COG0693	protein deglycase activity
ATC03_16210	COG1278	Cold shock
ATC03_16235	COG0277	FAD linked oxidase domain protein
ATC03_16250	COG1278	Cold shock
ATC03_16260	COG0730	response to heat
ATC03_16330	COG0183	Belongs to the thiolase family
ATC03_16335	COG1960	acyl-CoA dehydrogenase activity
ATC03_16360	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_16385	COG0559	Belongs to the binding-protein-dependent transport system permease family
ATC03_16390	COG0410	ABC transporter
ATC03_16395	COG0411	ABC transporter
ATC03_16420	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_16430	COG1404	Belongs to the peptidase S8 family
ATC03_16440	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATC03_16455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ATC03_16475	COG1349	DNA-binding transcription factor activity
ATC03_16555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ATC03_16585	COG4221	oxidoreductase activity
ATC03_16610	COG3401	FG-GAP repeat protein
ATC03_16630	COG1715	Restriction endonuclease
ATC03_16735	COG3795	YCII-related domain
ATC03_16775	COG0739	heme binding
ATC03_16775	COG0741	lytic transglycosylase activity
ATC03_16775	COG1196	nuclear chromosome segregation
ATC03_16785	COG2326	polyphosphate kinase activity
ATC03_16795	COG1733	regulation of RNA biosynthetic process
ATC03_16800	COG0702	epimerase
ATC03_16865	COG0740	serine-type endopeptidase activity
ATC03_16905	COG1737	Transcriptional regulator
ATC03_16920	COG1175	transmembrane transport
ATC03_16925	COG4977	sequence-specific DNA binding
ATC03_16930	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ATC03_16935	COG0352	thiamine-phosphate diphosphorylase activity
ATC03_16940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ATC03_16940	COG0352	thiamine-phosphate diphosphorylase activity
ATC03_16940	COG0351	phosphomethylpyrimidine kinase
ATC03_16945	COG1305	Transglutaminase-like
ATC03_16950	COG0702	epimerase
ATC03_16960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ATC03_16985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ATC03_16995	COG0154	amidase activity
ATC03_17000	COG2957	Belongs to the agmatine deiminase family
ATC03_17025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_17050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_17065	COG1122	ATPase activity
ATC03_17070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ATC03_17100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ATC03_17100	COG2111	Na H antiporter
ATC03_17105	COG1006	Multisubunit Na H antiporter MnhC subunit
ATC03_17200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ATC03_17205	COG2151	metal-sulfur cluster biosynthetic enzyme
ATC03_17210	COG3396	Phenylacetate-CoA oxygenase
ATC03_17215	COG3460	Phenylacetate-CoA oxygenase
ATC03_17220	COG3396	Phenylacetate-CoA oxygenase
ATC03_17235	COG1309	transcriptional regulator
ATC03_17240	COG0514	ATP-dependent DNA helicase (RecQ)
ATC03_17245	COG2030	dehydratase
ATC03_17245	COG1012	belongs to the aldehyde dehydrogenase family
ATC03_17250	COG1250	3-hydroxyacyl-CoA dehydrogenase
ATC03_17255	COG1024	Enoyl-CoA hydratase
ATC03_17365	COG1595	DNA-templated transcription, initiation
ATC03_17390	COG0586	Pfam SNARE associated Golgi protein
ATC03_17425	COG2986	histidine ammonia-lyase
ATC03_17430	COG0739	heme binding
ATC03_17430	COG0741	lytic transglycosylase activity
ATC03_17430	COG1196	nuclear chromosome segregation
ATC03_17435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ATC03_17440	COG1228	amidohydrolase
ATC03_17455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ATC03_17500	COG2409	Drug exporters of the RND superfamily
ATC03_17505	COG1309	transcriptional regulator
ATC03_17550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ATC03_17635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_17640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ATC03_17645	COG0531	amino acid
ATC03_17665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ATC03_17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_17685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ATC03_17705	COG4558	Periplasmic binding protein
ATC03_17710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_17715	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ATC03_17740	COG0151	Belongs to the GarS family
ATC03_17745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ATC03_17755	COG2514	catechol 2,3-dioxygenase activity
ATC03_17765	COG3483	tryptophan 2,3-dioxygenase activity
ATC03_17790	COG1695	Transcriptional regulator
ATC03_17795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATC03_17800	COG0047	phosphoribosylformylglycinamidine synthase activity
ATC03_17810	COG0318	PFAM AMP-dependent synthetase and ligase
ATC03_17820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ATC03_17830	COG2814	Major facilitator Superfamily
ATC03_17835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ATC03_17865	COG1063	alcohol dehydrogenase
ATC03_17875	COG0300	oxidoreductase activity
ATC03_17880	COG1605	Chorismate mutase
ATC03_17880	COG0287	Prephenate dehydrogenase
ATC03_17895	COG3397	chitin binding
ATC03_17905	COG1131	(ABC) transporter
ATC03_17910	COG1725	Transcriptional regulator
ATC03_17925	COG0697	spore germination
ATC03_17930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATC03_17955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATC03_17965	COG3275	phosphorelay sensor kinase activity
ATC03_17970	COG3279	Response regulator of the LytR AlgR family
ATC03_17980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ATC03_18000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ATC03_18015	COG0137	argininosuccinate synthase activity
ATC03_18025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ATC03_18080	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ATC03_18115	COG4251	negative regulation of phosphorylation
ATC03_18130	COG2199	diguanylate cyclase activity
ATC03_18130	COG2200	EAL domain
ATC03_18130	COG2202	Pas domain
ATC03_18245	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ATC03_18280	COG3119	arylsulfatase activity
ATC03_18300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ATC03_18310	COG1116	anion transmembrane transporter activity
ATC03_18310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ATC03_18315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_18325	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_18340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ATC03_18380	COG1063	alcohol dehydrogenase
ATC03_18390	COG0346	lactoylglutathione lyase activity
ATC03_18395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_18400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_18410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_18415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ATC03_18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ATC03_18435	COG1120	ATPase activity
ATC03_18470	COG0405	Gamma-glutamyltransferase
ATC03_18485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_18500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_18510	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
ATC03_18510	COG0778	Nitroreductase
ATC03_18540	COG0300	oxidoreductase activity
ATC03_18550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ATC03_18555	COG2271	Major facilitator Superfamily
ATC03_18565	COG1116	anion transmembrane transporter activity
ATC03_18575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ATC03_18580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ATC03_18595	COG1309	transcriptional regulator
ATC03_18640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ATC03_18650	COG0277	FAD linked oxidase domain protein
ATC03_18660	COG4585	Histidine kinase
ATC03_18665	COG2197	response regulator
ATC03_18670	COG2226	methyltransferase
ATC03_18675	COG0640	Transcriptional regulator
ATC03_18695	COG4152	abc transporter atp-binding protein
ATC03_18725	COG1309	transcriptional regulator
ATC03_18770	COG2272	Belongs to the type-B carboxylesterase lipase family
ATC03_18775	COG0477	Major facilitator Superfamily
ATC03_18785	COG4941	Belongs to the sigma-70 factor family
ATC03_18800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ATC03_18835	COG0596	Alpha beta hydrolase
ATC03_18850	COG3424	synthase
ATC03_18865	COG0628	permease
ATC03_18885	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ATC03_18905	COG0789	Transcriptional regulator
ATC03_18910	COG0484	heat shock protein binding
ATC03_18915	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ATC03_18920	COG0443	Heat shock 70 kDa protein
ATC03_18935	COG0477	Major facilitator Superfamily
ATC03_18980	COG4608	Belongs to the ABC transporter superfamily
ATC03_18985	COG0601	transmembrane transport
ATC03_18990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ATC03_18995	COG0444	Belongs to the ABC transporter superfamily
ATC03_19005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ATC03_19050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_19055	COG1280	lysine exporter protein (LysE YggA)
ATC03_19065	COG1063	alcohol dehydrogenase
ATC03_19085	COG1177	transmembrane transport
ATC03_19090	COG1176	ABC-type spermidine putrescine transport system, permease component I
ATC03_19095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ATC03_19100	COG3842	ATPase activity
ATC03_19125	COG2267	carboxylic ester hydrolase activity
ATC03_19140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ATC03_19150	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ATC03_19170	COG0717	Belongs to the dCTP deaminase family
ATC03_19195	COG1595	DNA-templated transcription, initiation
ATC03_19205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ATC03_19235	COG0739	heme binding
ATC03_19245	COG1063	alcohol dehydrogenase
ATC03_19250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ATC03_19260	COG3639	organic phosphonate transmembrane transporter activity
ATC03_19265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ATC03_19270	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ATC03_19285	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ATC03_19300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ATC03_19305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ATC03_19315	COG3336	cytochrome c oxidase
ATC03_19320	COG0776	regulation of translation
ATC03_19325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ATC03_19330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ATC03_19335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ATC03_19355	COG4175	Glycine betaine
ATC03_19355	COG0517	IMP dehydrogenase activity
ATC03_19365	COG0076	glutamate decarboxylase activity
ATC03_19375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATC03_19380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ATC03_19385	COG1121	(ABC) transporter
ATC03_19400	COG0508	dehydrogenase complex catalyzes the overall conversion of
ATC03_19405	COG0022	dehydrogenase e1 component
ATC03_19415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ATC03_19420	COG1950	PFAM Membrane protein of
ATC03_19440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ATC03_19445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ATC03_19460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ATC03_19465	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ATC03_19470	COG1414	Transcriptional regulator
ATC03_19495	COG0656	L-ascorbic acid biosynthetic process
ATC03_19505	COG1028	Short-chain dehydrogenase reductase Sdr
ATC03_19540	COG0765	amino acid transport
ATC03_19560	COG0305	Participates in initiation and elongation during chromosome replication
ATC03_19565	COG0359	binds to the 23S rRNA
ATC03_19570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ATC03_19580	COG0360	Binds together with S18 to 16S ribosomal RNA
ATC03_19585	COG0617	tRNA 3'-terminal CCA addition
ATC03_19605	COG3118	belongs to the thioredoxin family
ATC03_19610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ATC03_19615	COG1181	Belongs to the D-alanine--D-alanine ligase family
ATC03_19625	COG1192	Involved in chromosome partitioning
ATC03_19635	COG0357	Ribosomal RNA small subunit methyltransferase G
ATC03_19645	COG0706	membrane insertase activity
ATC03_19660	COG0230	Belongs to the bacterial ribosomal protein bL34 family