locus-tag	class	description
DCE93_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCE93_00010	COG0592	DNA-directed DNA polymerase activity
DCE93_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DCE93_00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
DCE93_00025	COG0187	DNA topoisomerase II activity
DCE93_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCE93_00075	COG0457	Tetratricopeptide repeat
DCE93_00075	COG0705	Rhomboid family
DCE93_00085	COG3764	Sortase (surface protein transpeptidase)
DCE93_00095	COG0515	serine threonine protein kinase
DCE93_00105	COG0768	penicillin binding
DCE93_00120	COG1716	ATPase activity
DCE93_00125	COG1716	ATPase activity
DCE93_00145	COG2378	regulation of single-species biofilm formation
DCE93_00235	COG1869	D-ribose catabolic process
DCE93_00240	COG1609	Transcriptional regulator
DCE93_00245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_00255	COG1063	alcohol dehydrogenase
DCE93_00260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCE93_00270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCE93_00315	COG0076	glutamate decarboxylase activity
DCE93_00320	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DCE93_00325	COG1511	domain protein
DCE93_00340	COG1864	DNA RNA non-specific endonuclease
DCE93_00340	COG3591	Belongs to the peptidase S1B family
DCE93_00345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DCE93_00360	COG1846	Transcriptional regulator
DCE93_00420	COG0640	Transcriptional regulator
DCE93_00445	COG3842	ATPase activity
DCE93_00460	COG0672	)-iron permease
DCE93_00470	COG2837	iron assimilation
DCE93_00485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCE93_00500	COG1672	PFAM Archaeal ATPase
DCE93_00500	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
DCE93_00505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCE93_00515	COG0490	domain, Protein
DCE93_00515	COG0471	metal ion transport
DCE93_00520	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DCE93_00520	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DCE93_00525	COG1309	transcriptional regulator
DCE93_00545	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DCE93_00550	COG0738	Major facilitator superfamily
DCE93_00555	COG1063	alcohol dehydrogenase
DCE93_00565	COG1609	Transcriptional regulator
DCE93_00580	COG0534	Mate efflux family protein
DCE93_00585	COG3590	peptidase
DCE93_00600	COG0494	nUDIX hydrolase
DCE93_00605	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DCE93_00610	COG0423	glycine-tRNA ligase activity
DCE93_00615	COG0519	Catalyzes the synthesis of GMP from XMP
DCE93_00620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DCE93_00630	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DCE93_00710	COG0181	hydroxymethylbilane synthase activity
DCE93_00720	COG0113	porphobilinogen synthase activity
DCE93_00725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DCE93_00750	COG1131	(ABC) transporter
DCE93_00785	COG1280	lysine exporter protein (LysE YggA)
DCE93_00800	COG2079	MmgE PrpD family protein
DCE93_00805	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DCE93_00835	COG1733	regulation of RNA biosynthetic process
DCE93_00880	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_00885	COG4067	protein conserved in archaea
DCE93_00885	COG0189	ligase activity
DCE93_00890	COG0189	ligase activity
DCE93_00890	COG0569	domain protein
DCE93_00895	COG1725	Transcriptional regulator
DCE93_00905	COG1834	amidinotransferase
DCE93_00910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DCE93_00920	COG0052	Belongs to the universal ribosomal protein uS2 family
DCE93_00940	COG2267	carboxylic ester hydrolase activity
DCE93_00950	COG3104	oligopeptide transport
DCE93_00955	COG0463	Glycosyl transferase, family 2
DCE93_00965	COG1309	transcriptional regulator
DCE93_00995	COG2186	Transcriptional regulator
DCE93_01000	COG2340	Cysteine-rich secretory protein family
DCE93_01010	COG0667	Aldo Keto reductase
DCE93_01020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DCE93_01035	COG1070	Carbohydrate kinase
DCE93_01040	COG3347	Dehydrogenase
DCE93_01040	COG1028	Short-chain dehydrogenase reductase Sdr
DCE93_01045	COG4952	isomerase
DCE93_01050	COG3254	rhamnose metabolic process
DCE93_01065	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCE93_01070	COG1129	ABC transporter
DCE93_01075	COG1609	Transcriptional regulator
DCE93_01080	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCE93_01085	COG2814	Major facilitator Superfamily
DCE93_01105	COG0095	Lipoate-protein ligase
DCE93_01115	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DCE93_01130	COG0395	ABC-type sugar transport system, permease component
DCE93_01145	COG1876	peptidase activity
DCE93_01150	COG0477	Major facilitator Superfamily
DCE93_01165	COG2733	membrane
DCE93_01170	COG0077	Prephenate dehydratase
DCE93_01180	COG1597	lipid kinase activity
DCE93_01185	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DCE93_01195	COG1316	TRANSCRIPTIONal
DCE93_01205	COG1316	TRANSCRIPTIONal
DCE93_01305	COG3546	catalase activity
DCE93_01320	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DCE93_01340	COG1028	Short-chain dehydrogenase reductase Sdr
DCE93_01385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DCE93_01395	COG0505	Belongs to the CarA family
DCE93_01400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DCE93_01410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DCE93_01415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCE93_01430	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DCE93_01435	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DCE93_01440	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DCE93_01460	COG0569	domain protein
DCE93_01465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DCE93_01470	COG0640	Transcriptional regulator
DCE93_01475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCE93_01500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DCE93_01505	COG0017	Asparaginyl-tRNA synthetase
DCE93_01510	COG0406	alpha-ribazole phosphatase activity
DCE93_01515	COG3118	belongs to the thioredoxin family
DCE93_01520	COG0785	Cytochrome C biogenesis protein
DCE93_01525	COG1333	cytochrome c biogenesis protein
DCE93_01530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DCE93_01550	COG0789	Transcriptional regulator
DCE93_01555	COG4948	Mandelate Racemase Muconate Lactonizing
DCE93_01585	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DCE93_01590	COG2326	polyphosphate kinase activity
DCE93_01595	COG1169	isochorismate synthase
DCE93_01600	COG2226	methyltransferase
DCE93_01605	COG0142	geranyltranstransferase activity
DCE93_01630	COG0494	nUDIX hydrolase
DCE93_01635	COG1666	GTP binding
DCE93_01640	COG1609	Transcriptional regulator
DCE93_01660	COG0739	heme binding
DCE93_01670	COG0366	Alpha amylase catalytic
DCE93_01675	COG2182	Extracellular solute-binding protein
DCE93_01680	COG1175	transmembrane transport
DCE93_01685	COG3833	ABC-type maltose transport systems, permease component
DCE93_01725	COG1113	amino acid transport
DCE93_01760	COG0438	transferase activity, transferring glycosyl groups
DCE93_01770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DCE93_01775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DCE93_01810	COG0601	transmembrane transport
DCE93_01815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCE93_01820	COG4172	Belongs to the ABC transporter superfamily
DCE93_01825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_01850	COG0385	Bile acid
DCE93_01910	COG2030	dehydratase
DCE93_01920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DCE93_01940	COG2197	response regulator
DCE93_01950	COG0318	PFAM AMP-dependent synthetase and ligase
DCE93_01955	COG2197	response regulator
DCE93_01960	COG4585	Histidine kinase
DCE93_01970	COG1131	(ABC) transporter
DCE93_01980	COG0583	DNA-binding transcription factor activity
DCE93_01985	COG0436	Aminotransferase
DCE93_01990	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DCE93_02010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DCE93_02015	COG0081	regulation of translation
DCE93_02025	COG1254	Belongs to the acylphosphatase family
DCE93_02035	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCE93_02075	COG0765	amino acid transport
DCE93_02080	COG1126	abc transporter atp-binding protein
DCE93_02100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCE93_02130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCE93_02145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCE93_02165	COG2271	Major facilitator Superfamily
DCE93_02195	COG0673	inositol 2-dehydrogenase activity
DCE93_02200	COG1129	ABC transporter
DCE93_02205	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCE93_02240	COG2197	response regulator
DCE93_02250	COG0745	RESPONSE REGULATOR receiver
DCE93_02255	COG2205	protein histidine kinase activity
DCE93_02265	COG0477	Major facilitator Superfamily
DCE93_02275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DCE93_02280	COG0222	ribosome binding
DCE93_02285	COG3152	Membrane
DCE93_02295	COG2814	Major facilitator Superfamily
DCE93_02305	COG1653	transport
DCE93_02310	COG1175	transmembrane transport
DCE93_02315	COG0395	ABC-type sugar transport system, permease component
DCE93_02315	COG0395	ABC-type sugar transport system, permease component
DCE93_02325	COG1132	(ABC) transporter
DCE93_02350	COG0330	HflC and HflK could
DCE93_02380	COG1129	ABC transporter
DCE93_02385	COG1172	Belongs to the binding-protein-dependent transport system permease family
DCE93_02420	COG1780	Probably involved in ribonucleotide reductase function
DCE93_02425	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCE93_02430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DCE93_02455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DCE93_02485	COG0583	DNA-binding transcription factor activity
DCE93_02530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DCE93_02545	COG0822	iron-sulfur transferase activity
DCE93_02585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_02595	COG0747	negative chemotaxis
DCE93_02600	COG0601	transmembrane transport
DCE93_02605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCE93_02610	COG4172	Belongs to the ABC transporter superfamily
DCE93_02615	COG2873	o-acetylhomoserine
DCE93_02625	COG0431	NADPH-dependent FMN reductase
DCE93_02655	COG3655	Transcriptional regulator
DCE93_02660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DCE93_02675	COG0488	(ABC) transporter
DCE93_02685	COG0019	diaminopimelate decarboxylase activity
DCE93_02705	COG1733	regulation of RNA biosynthetic process
DCE93_02730	COG1902	pentaerythritol trinitrate reductase activity
DCE93_02760	COG4585	Histidine kinase
DCE93_02765	COG2197	response regulator
DCE93_02835	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DCE93_02840	COG1695	Transcriptional regulator
DCE93_02845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCE93_02870	COG0542	response to heat
DCE93_02915	COG0494	nUDIX hydrolase
DCE93_02930	COG1793	dna ligase
DCE93_02950	COG3265	gluconokinase activity
DCE93_02970	COG3842	ATPase activity
DCE93_03000	COG0596	Alpha beta hydrolase
DCE93_03030	COG2226	methyltransferase
DCE93_03030	COG1073	alpha beta
DCE93_03070	COG1846	Transcriptional regulator
DCE93_03100	COG0477	Major facilitator Superfamily
DCE93_03110	COG4552	Acetyltransferase involved in intracellular survival and related
DCE93_03115	COG1609	Transcriptional regulator
DCE93_03120	COG1929	Belongs to the glycerate kinase type-1 family
DCE93_03135	COG5000	phosphorelay sensor kinase activity
DCE93_03135	COG5002	protein histidine kinase activity
DCE93_03140	COG0745	RESPONSE REGULATOR receiver
DCE93_03145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DCE93_03155	COG1061	Type III restriction enzyme res subunit
DCE93_03170	COG1278	Cold shock
DCE93_03185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DCE93_03195	COG3103	Sh3 type 3 domain protein
DCE93_03195	COG1388	LysM domain
DCE93_03195	COG0791	NLP P60 protein
DCE93_03220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCE93_03225	COG3548	integral membrane protein
DCE93_03235	COG1793	dna ligase
DCE93_03245	COG0686	Belongs to the AlaDH PNT family
DCE93_03270	COG1970	mechanosensitive ion channel activity
DCE93_03285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DCE93_03290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DCE93_03310	COG2159	amidohydrolase
DCE93_03315	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCE93_03335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DCE93_03340	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
DCE93_03350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCE93_03390	COG2985	domain, Protein
DCE93_03390	COG0490	domain, Protein
DCE93_03395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCE93_03410	COG0656	L-ascorbic acid biosynthetic process
DCE93_03420	COG1643	Atp-dependent helicase
DCE93_03450	COG1331	Highly conserved protein containing a thioredoxin domain
DCE93_03485	COG1362	aminopeptidase activity
DCE93_03505	COG1760	l-serine dehydratase
DCE93_03520	COG1832	CoA-binding protein
DCE93_03525	COG2873	o-acetylhomoserine
DCE93_03530	COG1335	isochorismatase
DCE93_03535	COG2329	Antibiotic biosynthesis monooxygenase
DCE93_03540	COG2076	Multidrug Resistance protein
DCE93_03550	COG1476	TRANSCRIPTIONal
DCE93_03565	COG2855	membrane
DCE93_03585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCE93_03590	COG0084	hydrolase, TatD family'
DCE93_03595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DCE93_03605	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DCE93_03610	COG0488	(ABC) transporter
DCE93_03620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DCE93_03625	COG2011	ABC-type metal ion transport system permease component
DCE93_03640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DCE93_03645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DCE93_03650	COG0318	PFAM AMP-dependent synthetase and ligase
DCE93_03670	COG2149	membrane
DCE93_03675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DCE93_03680	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DCE93_03685	COG0193	aminoacyl-tRNA hydrolase activity
DCE93_03705	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DCE93_03715	COG0124	histidyl-tRNA synthetase
DCE93_03725	COG0148	phosphopyruvate hydratase activity
DCE93_03740	COG1404	Belongs to the peptidase S8 family
DCE93_03760	COG0248	Ppx GppA phosphatase
DCE93_03790	COG1131	(ABC) transporter
DCE93_03795	COG1309	transcriptional regulator
DCE93_03800	COG1704	LemA family
DCE93_03810	COG3214	Protein conserved in bacteria
DCE93_03820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DCE93_03825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCE93_03845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCE93_03855	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DCE93_03860	COG0114	fumarate hydratase activity
DCE93_03875	COG1722	exodeoxyribonuclease VII activity
DCE93_03880	COG1570	exodeoxyribonuclease VII activity
DCE93_03885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DCE93_03895	COG0191	fructose-bisphosphate aldolase activity
DCE93_03920	COG1322	Protein conserved in bacteria
DCE93_03940	COG0583	DNA-binding transcription factor activity
DCE93_03960	COG3237	CsbD-like
DCE93_03970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCE93_03975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCE93_03980	COG0488	(ABC) transporter
DCE93_03995	COG2890	protein-(glutamine-N5) methyltransferase activity
DCE93_04010	COG2814	Major facilitator Superfamily
DCE93_04015	COG1104	cysteine desulfurase activity
DCE93_04025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DCE93_04030	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DCE93_04045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DCE93_04050	COG0509	glycine decarboxylation via glycine cleavage system
DCE93_04055	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCE93_04055	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DCE93_04095	COG4166	transmembrane transport
DCE93_04110	COG4172	Belongs to the ABC transporter superfamily
DCE93_04120	COG0739	heme binding
DCE93_04125	COG1024	Enoyl-CoA hydratase
DCE93_04160	COG2171	N-acyltransferase activity
DCE93_04165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCE93_04185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCE93_04190	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_04200	COG0076	glutamate decarboxylase activity
DCE93_04225	COG2239	Acts as a magnesium transporter
DCE93_04235	COG0006	proline dipeptidase activity
DCE93_04250	COG0513	Belongs to the DEAD box helicase family
DCE93_04310	COG3480	Lon protease (S16) C-terminal proteolytic domain
DCE93_04315	COG1615	UPF0182 protein
DCE93_04360	COG1175	transmembrane transport
DCE93_04365	COG0395	ABC-type sugar transport system, permease component
DCE93_04375	COG0628	permease
DCE93_04400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DCE93_04410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCE93_04480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DCE93_04485	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DCE93_04490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DCE93_04520	COG1595	DNA-templated transcription, initiation
DCE93_04530	COG2409	Drug exporters of the RND superfamily
DCE93_04535	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCE93_04535	COG0567	Dehydrogenase, E1 component
DCE93_04560	COG1011	Hydrolase
DCE93_04585	COG2814	Major facilitator Superfamily
DCE93_04605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DCE93_04625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DCE93_04630	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DCE93_04635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DCE93_04655	COG1120	ATPase activity
DCE93_04660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DCE93_04690	COG1842	Phage shock protein A
DCE93_04705	COG1595	DNA-templated transcription, initiation
DCE93_04725	COG0018	arginyl-trna synthetase
DCE93_04740	COG0460	homoserine dehydrogenase
DCE93_04750	COG0083	homoserine kinase activity
DCE93_04760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DCE93_04765	COG1045	serine acetyltransferase
DCE93_04775	COG2890	protein-(glutamine-N5) methyltransferase activity
DCE93_04800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCE93_04810	COG0356	it plays a direct role in the translocation of protons across the membrane
DCE93_04815	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCE93_04820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DCE93_04825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DCE93_04830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DCE93_04835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DCE93_04840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DCE93_04845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DCE93_04860	COG2818	Glycosylase
DCE93_04865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DCE93_04875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DCE93_04880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCE93_04895	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_04905	COG0631	protein serine/threonine phosphatase activity
DCE93_04920	COG0714	Associated with various cellular activities
DCE93_04950	COG3842	ATPase activity
DCE93_04955	COG1176	ABC-type spermidine putrescine transport system, permease component I
DCE93_04960	COG1177	transmembrane transport
DCE93_04970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DCE93_04985	COG0318	PFAM AMP-dependent synthetase and ligase
DCE93_04985	COG0204	Acyl-transferase
DCE93_04995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DCE93_05000	COG0750	zinc metalloprotease
DCE93_05005	COG4585	Histidine kinase
DCE93_05010	COG2197	response regulator
DCE93_05025	COG0183	Belongs to the thiolase family
DCE93_05035	COG0411	ABC transporter
DCE93_05040	COG0410	ABC transporter
DCE93_05045	COG0559	Belongs to the binding-protein-dependent transport system permease family
DCE93_05055	COG0318	PFAM AMP-dependent synthetase and ligase
DCE93_05065	COG1028	Short-chain dehydrogenase reductase Sdr
DCE93_05085	COG2267	carboxylic ester hydrolase activity
DCE93_05105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DCE93_05120	COG0442	prolyl-tRNA aminoacylation
DCE93_05140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DCE93_05145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DCE93_05165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DCE93_05170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DCE93_05190	COG2807	transmembrane transport
DCE93_05195	COG2390	Transcriptional regulator
DCE93_05200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DCE93_05205	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_05210	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_05220	COG0702	epimerase
DCE93_05230	COG1937	Protein conserved in bacteria
DCE93_05250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DCE93_05260	COG1051	belongs to the nudix hydrolase family
DCE93_05275	COG2252	PERMEase
DCE93_05280	COG2233	PERMEase
DCE93_05290	COG1609	Transcriptional regulator
DCE93_05300	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCE93_05315	COG0277	FAD linked oxidase domain protein
DCE93_05330	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_05340	COG0545	Peptidyl-prolyl cis-trans isomerase
DCE93_05370	COG3189	MarR family transcriptional regulator
DCE93_05385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DCE93_05400	COG0626	cystathionine gamma-synthase activity
DCE93_05405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_05415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DCE93_05480	COG1185	polyribonucleotide nucleotidyltransferase activity
DCE93_05505	COG0022	dehydrogenase e1 component
DCE93_05510	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCE93_05515	COG2154	pterin-4-alpha-carbinolamine dehydratase
DCE93_05525	COG1309	transcriptional regulator
DCE93_05530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCE93_05550	COG1960	acyl-CoA dehydrogenase activity
DCE93_05565	COG0667	Aldo Keto reductase
DCE93_05570	COG0612	Peptidase, M16
DCE93_05585	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DCE93_05595	COG1090	epimerase
DCE93_05615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DCE93_05635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DCE93_05640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DCE93_05655	COG0577	efflux transmembrane transporter activity
DCE93_05655	COG1136	(ABC) transporter
DCE93_05660	COG0577	efflux transmembrane transporter activity
DCE93_05670	COG1674	ftsk spoiiie
DCE93_05680	COG1546	Belongs to the CinA family
DCE93_05680	COG1058	Belongs to the CinA family
DCE93_05685	COG1396	sequence-specific DNA binding
DCE93_05695	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DCE93_05705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DCE93_05710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DCE93_05715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DCE93_05720	COG2890	protein-(glutamine-N5) methyltransferase activity
DCE93_05725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DCE93_05735	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DCE93_05740	COG2267	carboxylic ester hydrolase activity
DCE93_05745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DCE93_05755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCE93_05760	COG0131	Imidazoleglycerol-phosphate dehydratase
DCE93_05765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DCE93_05770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DCE93_05800	COG0443	Heat shock 70 kDa protein
DCE93_05815	COG1201	RNA secondary structure unwinding
DCE93_05820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCE93_05830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DCE93_05835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DCE93_05840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DCE93_05845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCE93_05850	COG1126	abc transporter atp-binding protein
DCE93_05855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DCE93_05860	COG0765	amino acid transport
DCE93_05865	COG0765	amino acid transport
DCE93_05870	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DCE93_05875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DCE93_05875	COG0072	phenylalanine-tRNA ligase activity
DCE93_05880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DCE93_05885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DCE93_05890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DCE93_05900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DCE93_05905	COG0165	Argininosuccinate lyase
DCE93_05910	COG2094	Belongs to the DNA glycosylase MPG family
DCE93_05925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DCE93_05970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DCE93_05975	COG0497	DNA recombination
DCE93_05980	COG0504	CTP synthase activity
DCE93_06000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DCE93_06005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DCE93_06020	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DCE93_06025	COG1160	GTP binding
DCE93_06060	COG0028	Belongs to the TPP enzyme family
DCE93_06095	COG3665	Urea carboxylase-associated protein
DCE93_06120	COG2197	response regulator
DCE93_06160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DCE93_06170	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCE93_06175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCE93_06210	COG2357	RelA SpoT domain protein
DCE93_06225	COG3012	SEC-C Motif Domain Protein
DCE93_06275	COG1192	Involved in chromosome partitioning
DCE93_06280	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DCE93_06300	COG1940	carbohydrate kinase activity
DCE93_06310	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DCE93_06315	COG0515	serine threonine protein kinase
DCE93_06315	COG2815	serine threonine protein kinase
DCE93_06320	COG1388	LysM domain
DCE93_06320	COG3942	CHAP domain
DCE93_06330	COG0142	geranyltranstransferase activity
DCE93_06340	COG2001	Belongs to the MraZ family
DCE93_06345	COG0275	rRNA processing
DCE93_06355	COG0768	penicillin binding
DCE93_06360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DCE93_06370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DCE93_06375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DCE93_06380	COG0772	Belongs to the SEDS family
DCE93_06385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DCE93_06390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DCE93_06400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DCE93_06410	COG1799	cell septum assembly
DCE93_06425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DCE93_06435	COG0587	DNA-directed DNA polymerase activity
DCE93_06440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DCE93_06445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DCE93_06450	COG0167	dihydroorotate dehydrogenase activity
DCE93_06470	COG1174	glycine betaine transport
DCE93_06480	COG1732	Glycine betaine
DCE93_06500	COG1271	oxidase subunit
DCE93_06505	COG1294	oxidase, subunit
DCE93_06515	COG1132	(ABC) transporter
DCE93_06525	COG0495	leucyl-tRNA aminoacylation
DCE93_06550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCE93_06600	COG0268	Binds directly to 16S ribosomal RNA
DCE93_06610	COG2197	response regulator
DCE93_06620	COG0481	GTPase activity
DCE93_06625	COG4762	Protein conserved in bacteria
DCE93_06645	COG1420	regulation of RNA biosynthetic process
DCE93_06650	COG0484	heat shock protein binding
DCE93_06660	COG0537	adenosine 5'-monophosphoramidase activity
DCE93_06670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DCE93_06680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DCE93_06685	COG4585	Histidine kinase
DCE93_06690	COG2197	response regulator
DCE93_06695	COG1136	(ABC) transporter
DCE93_06700	COG0577	efflux transmembrane transporter activity
DCE93_06705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DCE93_06710	COG2860	membrane
DCE93_06715	COG1381	Involved in DNA repair and RecF pathway recombination
DCE93_06720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DCE93_06730	COG0442	prolyl-tRNA aminoacylation
DCE93_06740	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DCE93_06745	COG0358	DNA primase activity
DCE93_06755	COG0601	transmembrane transport
DCE93_06770	COG0444	Belongs to the ABC transporter superfamily
DCE93_06810	COG0582	viral genome integration into host DNA
DCE93_06840	COG0189	ligase activity
DCE93_06855	COG3177	Filamentation induced by cAMP protein fic
DCE93_06860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCE93_06870	COG2815	serine threonine protein kinase
DCE93_06870	COG0515	serine threonine protein kinase
DCE93_06875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCE93_06915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DCE93_06920	COG0581	inorganic phosphate transmembrane transporter activity
DCE93_06925	COG0573	inorganic phosphate transmembrane transporter activity
DCE93_06955	COG3119	arylsulfatase activity
DCE93_06975	COG0628	permease
DCE93_06990	COG2508	Transcriptional regulator
DCE93_07005	COG4325	translation initiation factor activity
DCE93_07055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DCE93_07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCE93_07065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DCE93_07070	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DCE93_07080	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DCE93_07115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DCE93_07145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DCE93_07150	COG0174	glutamine synthetase
DCE93_07155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DCE93_07160	COG0174	glutamine synthetase
DCE93_07175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DCE93_07180	COG0321	lipoyl(octanoyl) transferase activity
DCE93_07190	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCE93_07195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DCE93_07200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DCE93_07210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DCE93_07230	COG0187	DNA topoisomerase II activity
DCE93_07235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DCE93_07250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DCE93_07260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DCE93_07265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DCE93_07280	COG2226	methyltransferase
DCE93_07285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DCE93_07290	COG0723	plastoquinol--plastocyanin reductase activity
DCE93_07295	COG2010	Cytochrome c
DCE93_07300	COG1845	cytochrome c oxidase, subunit III
DCE93_07305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DCE93_07310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCE93_07315	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DCE93_07320	COG2376	Dihydroxyacetone kinase
DCE93_07325	COG1461	Dihydroxyacetone kinase
DCE93_07335	COG1028	Short-chain dehydrogenase reductase Sdr
DCE93_07365	COG0596	Alpha beta hydrolase
DCE93_07380	COG1473	amidohydrolase
DCE93_07420	COG4581	dead DEAH box helicase
DCE93_07425	COG0805	protein transport
DCE93_07430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DCE93_07440	COG2378	regulation of single-species biofilm formation
DCE93_07465	COG1968	undecaprenyl-diphosphatase activity
DCE93_07490	COG0587	DNA-directed DNA polymerase activity
DCE93_07500	COG1028	Short-chain dehydrogenase reductase Sdr
DCE93_07515	COG0626	cystathionine gamma-synthase activity
DCE93_07535	COG1686	Belongs to the peptidase S11 family
DCE93_07575	COG0346	lactoylglutathione lyase activity
DCE93_07580	COG0254	rRNA binding
DCE93_07585	COG1119	ATPase activity
DCE93_07595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DCE93_07600	COG3830	Belongs to the UPF0237 family
DCE93_07600	COG0560	Phosphoserine phosphatase
DCE93_07610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCE93_07615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DCE93_07620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DCE93_07645	COG0488	(ABC) transporter
DCE93_07685	COG0022	dehydrogenase e1 component
DCE93_07690	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCE93_07700	COG0386	Belongs to the glutathione peroxidase family
DCE93_07715	COG2501	S4 domain
DCE93_07730	COG0799	negative regulation of ribosome biogenesis
DCE93_07740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DCE93_07750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DCE93_07755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DCE93_07760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DCE93_07765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DCE93_07770	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DCE93_07780	COG1530	ribonuclease E activity
DCE93_07790	COG0105	UTP biosynthetic process
DCE93_07800	COG0285	dihydrofolate synthase activity
DCE93_07805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DCE93_07815	COG0477	Major facilitator Superfamily
DCE93_07820	COG0525	valine-tRNA ligase activity
DCE93_07835	COG2226	methyltransferase
DCE93_07840	COG0339	signal peptide processing
DCE93_07845	COG2151	metal-sulfur cluster biosynthetic enzyme
DCE93_07850	COG0396	ATPase activity
DCE93_07875	COG0109	protoheme IX farnesyltransferase activity
DCE93_07885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DCE93_07905	COG0363	glucosamine-6-phosphate deaminase activity
DCE93_07915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DCE93_07920	COG0149	triose-phosphate isomerase activity
DCE93_07925	COG0126	phosphoglycerate kinase activity
DCE93_07940	COG1481	regulation of sporulation
DCE93_07945	COG1660	Displays ATPase and GTPase activities
DCE93_07950	COG0322	excinuclease ABC activity
DCE93_07960	COG0556	nucleotide-excision repair
DCE93_07965	COG0237	dephospho-CoA kinase activity
DCE93_08010	COG0070	glutamate synthase
DCE93_08010	COG0069	glutamate synthase activity
DCE93_08010	COG0067	glutamate synthase
DCE93_08015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DCE93_08020	COG0159	tryptophan synthase activity
DCE93_08025	COG0133	tryptophan synthase activity
DCE93_08030	COG0134	indole-3-glycerol-phosphate synthase activity
DCE93_08050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DCE93_08055	COG0107	imidazoleglycerol-phosphate synthase activity
DCE93_08060	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DCE93_08065	COG0140	phosphoribosyl-ATP diphosphatase activity
DCE93_08070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DCE93_08080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DCE93_08090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DCE93_08100	COG1758	RNA polymerase activity
DCE93_08105	COG0194	GDP metabolic process
DCE93_08110	COG0284	orotidine-5'-phosphate decarboxylase activity
DCE93_08115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DCE93_08120	COG0505	Belongs to the CarA family
DCE93_08130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCE93_08135	COG0540	Belongs to the ATCase OTCase family
DCE93_08140	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DCE93_08150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DCE93_08155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DCE93_08160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DCE93_08165	COG0584	glycerophosphoryl diester phosphodiesterase
DCE93_08170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DCE93_08175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DCE93_08180	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DCE93_08185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DCE93_08195	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DCE93_08200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DCE93_08210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DCE93_08225	COG1196	nuclear chromosome segregation
DCE93_08235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCE93_08240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCE93_08245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DCE93_08255	COG2255	four-way junction helicase activity
DCE93_08260	COG0632	four-way junction helicase activity
DCE93_08265	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DCE93_08270	COG0217	transcriptional regulatory protein
DCE93_08285	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DCE93_08290	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DCE93_08300	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
DCE93_08310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DCE93_08360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DCE93_08385	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DCE93_08390	COG0183	Belongs to the thiolase family
DCE93_08395	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCE93_08395	COG1024	Enoyl-CoA hydratase
DCE93_08400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DCE93_08405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DCE93_08420	COG0756	dUTP diphosphatase activity
DCE93_08445	COG3135	benzoate transporter
DCE93_08450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DCE93_08455	COG0740	serine-type endopeptidase activity
DCE93_08460	COG0740	serine-type endopeptidase activity
DCE93_08470	COG0544	peptidyl-prolyl cis-trans isomerase activity
DCE93_08505	COG0783	Belongs to the Dps family
DCE93_08515	COG2197	response regulator
DCE93_08525	COG2132	Multicopper oxidase
DCE93_08530	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DCE93_08565	COG4585	Histidine kinase
DCE93_08570	COG2197	response regulator
DCE93_08580	COG0668	transmembrane transport
DCE93_08600	COG1946	Acyl-CoA thioesterase
DCE93_08635	COG0667	Aldo Keto reductase
DCE93_08650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DCE93_08655	COG0475	glutathione-regulated potassium exporter activity
DCE93_08665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DCE93_08700	COG1122	ATPase activity
DCE93_08705	COG4721	ABC-type cobalt transport system, permease component
DCE93_08715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DCE93_08725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCE93_08730	COG0154	amidase activity
DCE93_08735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DCE93_08740	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DCE93_08745	COG0482	sulfurtransferase activity
DCE93_08765	COG0058	SHG alpha-glucan phosphorylase activity
DCE93_08770	COG0366	Alpha amylase catalytic
DCE93_08775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DCE93_08825	COG0233	cytoplasmic translational termination
DCE93_08830	COG0528	UMP kinase activity
DCE93_08835	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DCE93_08840	COG0052	Belongs to the universal ribosomal protein uS2 family
DCE93_08850	COG4974	Belongs to the 'phage' integrase family
DCE93_08865	COG0606	chelatase, subunit chli
DCE93_08870	COG0792	nuclease activity
DCE93_08880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DCE93_08890	COG0335	large ribosomal subunit rRNA binding
DCE93_08900	COG0024	Methionine aminopeptidase
DCE93_08905	COG2146	nitrite reductase [NAD(P)H] activity
DCE93_08910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DCE93_08915	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DCE93_08915	COG1648	precorrin-2 dehydrogenase activity
DCE93_08925	COG2223	nitrite transmembrane transporter activity
DCE93_08930	COG0243	molybdopterin cofactor binding
DCE93_08940	COG0303	'Molybdopterin
DCE93_08950	COG0746	molybdenum cofactor guanylyltransferase activity
DCE93_08960	COG0336	Belongs to the RNA methyltransferase TrmD family
DCE93_08965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DCE93_08970	COG1837	Belongs to the UPF0109 family
DCE93_08975	COG0228	four-way junction DNA binding
DCE93_08980	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCE93_09020	COG1196	nuclear chromosome segregation
DCE93_09030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DCE93_09035	COG0571	ribonuclease III activity
DCE93_09040	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DCE93_09060	COG0714	Associated with various cellular activities
DCE93_09065	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DCE93_09070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DCE93_09080	COG0742	ribosomal rna small subunit methyltransferase
DCE93_09095	COG1181	Belongs to the D-alanine--D-alanine ligase family
DCE93_09100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DCE93_09110	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DCE93_09115	COG0066	3-isopropylmalate dehydratase activity
DCE93_09120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DCE93_09130	COG0861	Integral membrane protein TerC family
DCE93_09200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DCE93_09205	COG0583	DNA-binding transcription factor activity
DCE93_09215	COG0179	Fumarylacetoacetate (FAA) hydrolase
DCE93_09220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DCE93_09225	COG0473	3-isopropylmalate dehydrogenase activity
DCE93_09230	COG0477	Major facilitator Superfamily
DCE93_09265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DCE93_09270	COG0440	acetolactate synthase activity
DCE93_09275	COG0028	Belongs to the TPP enzyme family
DCE93_09280	COG0129	dihydroxy-acid dehydratase activity
DCE93_09290	COG1511	domain protein
DCE93_09295	COG2409	Drug exporters of the RND superfamily
DCE93_09315	COG1268	BioY protein
DCE93_09320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCE93_09325	COG0183	Belongs to the thiolase family
DCE93_09330	COG1122	ATPase activity
DCE93_09335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCE93_09345	COG0483	inositol monophosphate 1-phosphatase activity
DCE93_09360	COG0697	spore germination
DCE93_09365	COG0583	DNA-binding transcription factor activity
DCE93_09385	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DCE93_09400	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DCE93_09460	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DCE93_09470	COG5398	heme oxygenase
DCE93_09475	COG0586	Pfam SNARE associated Golgi protein
DCE93_09485	COG0596	Alpha beta hydrolase
DCE93_09535	COG0653	protein targeting
DCE93_09540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DCE93_09550	COG5401	PFAM Sporulation and spore germination
DCE93_09555	COG5000	phosphorelay sensor kinase activity
DCE93_09555	COG5002	protein histidine kinase activity
DCE93_09560	COG0745	RESPONSE REGULATOR receiver
DCE93_09580	COG0714	Associated with various cellular activities
DCE93_09600	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DCE93_09605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCE93_09630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCE93_09640	COG1482	cell wall glycoprotein biosynthetic process
DCE93_09645	COG1960	acyl-CoA dehydrogenase activity
DCE93_09660	COG0463	Glycosyl transferase, family 2
DCE93_09685	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DCE93_09690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DCE93_09715	COG1216	Glycosyl transferase, family 2
DCE93_09730	COG1215	transferase activity, transferring glycosyl groups
DCE93_09735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DCE93_09790	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DCE93_09795	COG0438	transferase activity, transferring glycosyl groups
DCE93_09795	COG1216	Glycosyl transferase, family 2
DCE93_09800	COG1088	dTDP-glucose 4,6-dehydratase activity
DCE93_09860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DCE93_09885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DCE93_09890	COG0424	maF-like protein
DCE93_09895	COG4770	biotin carboxylase activity
DCE93_09905	COG0531	amino acid
DCE93_09920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCE93_09930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DCE93_09935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DCE93_09965	COG1744	ABC transporter substrate-binding protein PnrA-like
DCE93_09980	COG2009	succinate dehydrogenase
DCE93_09990	COG1053	succinate dehydrogenase
DCE93_09995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DCE93_10020	COG1011	Hydrolase
DCE93_10025	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DCE93_10030	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DCE93_10040	COG2390	Transcriptional regulator
DCE93_10055	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCE93_10055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DCE93_10060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DCE93_10070	COG0477	Major facilitator Superfamily
DCE93_10095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DCE93_10095	COG1648	precorrin-2 dehydrogenase activity
DCE93_10100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCE93_10105	COG1116	anion transmembrane transporter activity
DCE93_10140	COG1132	(ABC) transporter
DCE93_10155	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DCE93_10180	COG0183	Belongs to the thiolase family
DCE93_10200	COG0477	Major facilitator Superfamily
DCE93_10205	COG3971	2-oxopent-4-enoate hydratase activity
DCE93_10215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DCE93_10245	COG1335	isochorismatase
DCE93_10250	COG2027	D-alanyl-D-alanine carboxypeptidase
DCE93_10270	COG0470	DNA polymerase III
DCE93_10275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DCE93_10280	COG1754	DNA topoisomerase type I activity
DCE93_10280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DCE93_10315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DCE93_10330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DCE93_10335	COG1408	metallophosphoesterase
DCE93_10345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DCE93_10400	COG0488	(ABC) transporter
DCE93_10405	COG0579	oxidoreductase
DCE93_10420	COG1486	melibiose metabolic process
DCE93_10430	COG4608	Belongs to the ABC transporter superfamily
DCE93_10435	COG0444	Belongs to the ABC transporter superfamily
DCE93_10440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DCE93_10445	COG0601	transmembrane transport
DCE93_10455	COG0800	Aldolase
DCE93_10470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DCE93_10490	COG0745	RESPONSE REGULATOR receiver
DCE93_10510	COG5002	protein histidine kinase activity
DCE93_10535	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DCE93_10545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DCE93_10555	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DCE93_10580	COG0456	acetyltransferase
DCE93_10585	COG0433	COG0433 Predicted ATPase
DCE93_10590	COG3285	dna ligase
DCE93_10590	COG1793	dna ligase
DCE93_10600	COG4948	Mandelate Racemase Muconate Lactonizing
DCE93_10625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCE93_10630	COG3257	ureidoglycine aminohydrolase activity
DCE93_10650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DCE93_10660	COG0590	tRNA wobble adenosine to inosine editing
DCE93_10685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DCE93_10710	COG0315	cyclic pyranopterin monophosphate synthase activity
DCE93_10725	COG2814	Major facilitator Superfamily
DCE93_10730	COG0459	protein refolding
DCE93_10735	COG1470	cell adhesion involved in biofilm formation
DCE93_10740	COG1278	Cold shock
DCE93_10755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DCE93_10780	COG3842	ATPase activity
DCE93_10790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DCE93_10795	COG0215	cysteine-tRNA ligase activity
DCE93_10800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DCE93_10800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DCE93_10815	COG0745	RESPONSE REGULATOR receiver
DCE93_10830	COG0588	phosphoglycerate mutase activity
DCE93_10835	COG0354	folic acid binding
DCE93_10840	COG3485	protocatechuate 3,4-dioxygenase
DCE93_10850	COG0745	RESPONSE REGULATOR receiver
DCE93_10855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DCE93_10880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCE93_10905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_10915	COG1595	DNA-templated transcription, initiation
DCE93_10935	COG2017	converts alpha-aldose to the beta-anomer
DCE93_10940	COG1349	DNA-binding transcription factor activity
DCE93_10950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DCE93_10975	COG2089	acid synthase
DCE93_10980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DCE93_10985	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DCE93_10990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DCE93_11005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DCE93_11015	COG1349	DNA-binding transcription factor activity
DCE93_11020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DCE93_11050	COG1472	Belongs to the glycosyl hydrolase 3 family
DCE93_11055	COG0395	ABC-type sugar transport system, permease component
DCE93_11060	COG1175	transmembrane transport
DCE93_11070	COG1940	carbohydrate kinase activity
DCE93_11075	COG2217	Heavy metal translocating P-type atpase
DCE93_11100	COG2197	response regulator
DCE93_11105	COG1132	(ABC) transporter
DCE93_11115	COG1834	amidinotransferase
DCE93_11120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DCE93_11125	COG0138	bifunctional purine biosynthesis protein purh
DCE93_11160	COG0045	succinate-CoA ligase (ADP-forming) activity
DCE93_11180	COG0584	glycerophosphoryl diester phosphodiesterase
DCE93_11190	COG0039	L-malate dehydrogenase activity
DCE93_11195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DCE93_11195	COG0519	Catalyzes the synthesis of GMP from XMP
DCE93_11240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DCE93_11245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DCE93_11265	COG0489	protein tyrosine kinase activity
DCE93_11270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DCE93_11275	COG0516	GMP reductase activity
DCE93_11305	COG0411	ABC transporter
DCE93_11325	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DCE93_11350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DCE93_11355	COG0456	acetyltransferase
DCE93_11365	COG0802	atpase or kinase
DCE93_11370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DCE93_11375	COG0736	holo-[acyl-carrier-protein] synthase activity
DCE93_11380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DCE93_11385	COG1072	(Pantothenic acid kinase))
DCE93_11390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DCE93_11395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DCE93_11400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DCE93_11405	COG0101	tRNA pseudouridine synthase activity
DCE93_11410	COG0203	ribosomal protein L17
DCE93_11415	COG0202	RNA polymerase activity
DCE93_11420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DCE93_11425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DCE93_11430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DCE93_11435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DCE93_11440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DCE93_11445	COG0024	Methionine aminopeptidase
DCE93_11450	COG0563	adenylate kinase activity
DCE93_11460	COG0200	Binds to the 23S rRNA
DCE93_11465	COG1841	ribosomal large subunit assembly
DCE93_11470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DCE93_11475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DCE93_11480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DCE93_11485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DCE93_11490	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DCE93_11495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DCE93_11500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DCE93_11505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DCE93_11510	COG0255	Belongs to the universal ribosomal protein uL29 family
DCE93_11515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DCE93_11520	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DCE93_11525	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DCE93_11530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DCE93_11535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DCE93_11540	COG0089	rRNA binding
DCE93_11545	COG0088	Forms part of the polypeptide exit tunnel
DCE93_11550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DCE93_11555	COG0051	transcription antitermination factor activity, RNA binding
DCE93_11565	COG2755	lipolytic protein G-D-S-L family
DCE93_11565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DCE93_11570	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DCE93_11575	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DCE93_11580	COG0049	tRNA binding
DCE93_11585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DCE93_11605	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DCE93_11610	COG0085	RNA polymerase activity
DCE93_11635	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DCE93_11675	COG0513	Belongs to the DEAD box helicase family
DCE93_11705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DCE93_11705	COG0519	Catalyzes the synthesis of GMP from XMP
DCE93_11710	COG2261	transglycosylase associated protein
DCE93_11750	COG2072	flavoprotein involved in K transport
DCE93_11755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DCE93_11775	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DCE93_11780	COG0542	response to heat
DCE93_11790	COG3655	Transcriptional regulator
DCE93_11805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DCE93_11810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DCE93_11815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DCE93_11845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DCE93_11850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DCE93_11855	COG0302	gtp cyclohydrolase
DCE93_11860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DCE93_11870	COG0037	tRNA processing
DCE93_11875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DCE93_12010	COG0596	Alpha beta hydrolase
DCE93_12025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DCE93_12025	COG1796	DNA polymerase
DCE93_12035	COG1063	alcohol dehydrogenase
DCE93_12040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DCE93_12045	COG0697	spore germination
DCE93_12050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DCE93_12055	COG0579	oxidoreductase
DCE93_12090	COG0463	Glycosyl transferase, family 2
DCE93_12110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DCE93_12120	COG0318	PFAM AMP-dependent synthetase and ligase
DCE93_12140	COG1215	transferase activity, transferring glycosyl groups
DCE93_12145	COG0438	transferase activity, transferring glycosyl groups
DCE93_12150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DCE93_12160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DCE93_12165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DCE93_12210	COG0039	L-malate dehydrogenase activity
DCE93_12240	COG0514	ATP-dependent DNA helicase (RecQ)
DCE93_12245	COG4085	toxin activity
DCE93_12245	COG1525	nuclease
DCE93_12245	COG0737	Belongs to the 5'-nucleotidase family
DCE93_12270	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DCE93_12305	COG0640	Transcriptional regulator
DCE93_12325	COG1278	Cold shock
DCE93_12335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DCE93_12340	COG1278	Cold shock
DCE93_12355	COG4941	Belongs to the sigma-70 factor family
DCE93_12360	COG3795	YCII-related domain
DCE93_12365	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DCE93_12395	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCE93_12440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DCE93_12450	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DCE93_12450	COG2066	Belongs to the glutaminase family
DCE93_12465	COG2197	response regulator
DCE93_12505	COG1322	Protein conserved in bacteria
DCE93_12515	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DCE93_12545	COG0494	nUDIX hydrolase
DCE93_12580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DCE93_12595	COG1690	Belongs to the RtcB family
DCE93_12605	COG2197	response regulator
DCE93_12610	COG2072	flavoprotein involved in K transport
DCE93_12620	COG4977	sequence-specific DNA binding
DCE93_12630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DCE93_12640	COG4129	membrane
DCE93_12670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DCE93_12685	COG0154	amidase activity
DCE93_12690	COG2957	Belongs to the agmatine deiminase family
DCE93_12725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_12740	COG3119	arylsulfatase activity
DCE93_12750	COG1122	ATPase activity
DCE93_12755	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DCE93_12785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DCE93_12785	COG2111	Na H antiporter
DCE93_12790	COG1006	Multisubunit Na H antiporter MnhC subunit
DCE93_12820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DCE93_12825	COG2151	metal-sulfur cluster biosynthetic enzyme
DCE93_12830	COG3396	Phenylacetate-CoA oxygenase
DCE93_12835	COG3460	Phenylacetate-CoA oxygenase
DCE93_12840	COG3396	Phenylacetate-CoA oxygenase
DCE93_12845	COG2050	protein possibly involved in aromatic compounds catabolism
DCE93_12855	COG1309	transcriptional regulator
DCE93_12865	COG0514	ATP-dependent DNA helicase (RecQ)
DCE93_12875	COG2030	dehydratase
DCE93_12875	COG1012	belongs to the aldehyde dehydrogenase family
DCE93_12880	COG1250	3-hydroxyacyl-CoA dehydrogenase
DCE93_12890	COG0183	Belongs to the thiolase family
DCE93_12900	COG0513	Belongs to the DEAD box helicase family
DCE93_12920	COG4585	Histidine kinase
DCE93_12925	COG2197	response regulator
DCE93_12955	COG2986	histidine ammonia-lyase
DCE93_12960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DCE93_13010	COG0515	serine threonine protein kinase
DCE93_13025	COG0739	heme binding
DCE93_13025	COG0741	lytic transglycosylase activity
DCE93_13025	COG1196	nuclear chromosome segregation
DCE93_13030	COG2986	histidine ammonia-lyase
DCE93_13040	COG0517	IMP dehydrogenase activity
DCE93_13040	COG1125	glycine betaine transport
DCE93_13050	COG1174	glycine betaine transport
DCE93_13060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DCE93_13065	COG1228	amidohydrolase
DCE93_13080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DCE93_13095	COG0395	ABC-type sugar transport system, permease component
DCE93_13100	COG1175	transmembrane transport
DCE93_13105	COG1940	carbohydrate kinase activity
DCE93_13105	COG1846	Transcriptional regulator
DCE93_13110	COG0588	phosphoglycerate mutase activity
DCE93_13125	COG2217	Heavy metal translocating P-type atpase
DCE93_13130	COG3387	PFAM Glycoside hydrolase 15-related
DCE93_13145	COG4941	Belongs to the sigma-70 factor family
DCE93_13150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DCE93_13195	COG0531	amino acid
DCE93_13220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DCE93_13230	COG2050	protein possibly involved in aromatic compounds catabolism
DCE93_13250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DCE93_13255	COG0151	Belongs to the GarS family
DCE93_13260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DCE93_13265	COG2514	catechol 2,3-dioxygenase activity
DCE93_13275	COG3483	tryptophan 2,3-dioxygenase activity
DCE93_13295	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCE93_13300	COG0047	phosphoribosylformylglycinamidine synthase activity
DCE93_13325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DCE93_13335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DCE93_13340	COG2814	Major facilitator Superfamily
DCE93_13345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DCE93_13380	COG1063	alcohol dehydrogenase
DCE93_13400	COG1605	Chorismate mutase
DCE93_13400	COG0287	Prephenate dehydrogenase
DCE93_13410	COG1131	(ABC) transporter
DCE93_13415	COG1725	Transcriptional regulator
DCE93_13420	COG0697	spore germination
DCE93_13430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DCE93_13440	COG3275	phosphorelay sensor kinase activity
DCE93_13445	COG3279	Response regulator of the LytR AlgR family
DCE93_13455	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DCE93_13475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DCE93_13485	COG0137	argininosuccinate synthase activity
DCE93_13495	COG0598	Magnesium transport protein CorA
DCE93_13525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DCE93_13535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DCE93_13545	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DCE93_13550	COG3340	Belongs to the peptidase S51 family
DCE93_13565	COG1546	Belongs to the CinA family
DCE93_13565	COG1058	Belongs to the CinA family
DCE93_13575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DCE93_13580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DCE93_13585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCE93_13590	COG1116	anion transmembrane transporter activity
DCE93_13595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DCE93_13605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DCE93_13625	COG1349	DNA-binding transcription factor activity
DCE93_13645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DCE93_13650	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DCE93_13660	COG1131	(ABC) transporter
DCE93_13670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_13680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_13685	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
DCE93_13685	COG0778	Nitroreductase
DCE93_13715	COG0300	oxidoreductase activity
DCE93_13720	COG1309	transcriptional regulator
DCE93_13735	COG1028	Short-chain dehydrogenase reductase Sdr
DCE93_13755	COG2197	response regulator
DCE93_13760	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DCE93_13765	COG0640	Transcriptional regulator
DCE93_13780	COG4152	abc transporter atp-binding protein
DCE93_13800	COG1063	alcohol dehydrogenase
DCE93_13820	COG2272	Belongs to the type-B carboxylesterase lipase family
DCE93_13830	COG0542	response to heat
DCE93_13840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DCE93_13875	COG0628	permease
DCE93_13910	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DCE93_13915	COG2813	Specifically methylates the guanine in position
DCE93_13925	COG0789	Transcriptional regulator
DCE93_13930	COG0484	heat shock protein binding
DCE93_13935	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DCE93_13940	COG0443	Heat shock 70 kDa protein
DCE93_13960	COG0477	Major facilitator Superfamily
DCE93_13975	COG0717	Belongs to the dCTP deaminase family
DCE93_13985	COG1595	DNA-templated transcription, initiation
DCE93_14010	COG0477	Major facilitator Superfamily
DCE93_14020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DCE93_14025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DCE93_14035	COG3336	cytochrome c oxidase
DCE93_14040	COG0776	regulation of translation
DCE93_14045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DCE93_14050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DCE93_14055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DCE93_14060	COG1609	Transcriptional regulator
DCE93_14070	COG1609	Transcriptional regulator
DCE93_14100	COG0076	glutamate decarboxylase activity
DCE93_14110	COG4176	ABC-type proline glycine betaine transport system permease component
DCE93_14130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DCE93_14135	COG1121	(ABC) transporter
DCE93_14140	COG0803	Belongs to the bacterial solute-binding protein 9 family
DCE93_14150	COG0508	dehydrogenase complex catalyzes the overall conversion of
DCE93_14155	COG0022	dehydrogenase e1 component
DCE93_14165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DCE93_14170	COG1950	PFAM Membrane protein of
DCE93_14185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DCE93_14190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DCE93_14205	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DCE93_14210	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DCE93_14215	COG1414	Transcriptional regulator
DCE93_14255	COG1695	Transcriptional regulator
DCE93_14265	COG0305	Participates in initiation and elongation during chromosome replication
DCE93_14270	COG0359	binds to the 23S rRNA
DCE93_14275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DCE93_14285	COG0360	Binds together with S18 to 16S ribosomal RNA
DCE93_14290	COG0617	tRNA 3'-terminal CCA addition
DCE93_14310	COG3118	belongs to the thioredoxin family
DCE93_14315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DCE93_14330	COG1192	Involved in chromosome partitioning
DCE93_14335	COG0357	Ribosomal RNA small subunit methyltransferase G
DCE93_14345	COG0706	membrane insertase activity
DCE93_14350	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DCE93_14355	COG0594	ribonuclease P activity
DCE93_14360	COG0230	Belongs to the bacterial ribosomal protein bL34 family