locus-tag	class	description
C7S18_00075	ENOG4105VV5	Plasmid stabilization system
C7S18_00090	ENOG4105F2I	Transposase
C7S18_00140	ENOG4105VEQ	Cold shock protein
C7S18_00180	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
C7S18_00195	ENOG4105E18	UPF0276 protein
C7S18_00205	ENOG4105CSM	endonuclease III
C7S18_00210	ENOG4105BZU	Histidine kinase
C7S18_00215	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C7S18_00220	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C7S18_00225	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C7S18_00245	ENOG4108M24	von Willebrand factor, type A
C7S18_00250	ENOG4105UM3	Inherit from NOG: serine threonine phosphoprotein phosphatase
C7S18_00255	ENOG4106E1W	protein with protein kinase and helix-hairpin-helix DNA-binding
C7S18_00260	ENOG4106E1W	protein with protein kinase and helix-hairpin-helix DNA-binding
C7S18_00275	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C7S18_00280	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
C7S18_00285	ENOG4107YZP	Rhodanese domain protein
C7S18_00305	ENOG4107QWB	Ornithine cyclodeaminase
C7S18_00345	ENOG4105K64	Glycosyl transferase, family 2
C7S18_00355	ENOG4107EFQ	arachidonate 15-lipoxygenase
C7S18_00365	ENOG4107QP3	malate synthase g
C7S18_00375	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C7S18_00385	ENOG4105VIE	preprotein translocase, subunit YajC
C7S18_00395	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C7S18_00405	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C7S18_00410	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C7S18_00415	ENOG4105DFU	Cell wall formation (By similarity)
C7S18_00420	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C7S18_00425	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C7S18_00440	ENOG4105E27	serine threonine protein kinase
C7S18_00450	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C7S18_00455	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C7S18_00460	ENOG4107RIQ	Sulfate adenylate transferase
C7S18_00465	ENOG4108RXX	maleylacetoacetate isomerase
C7S18_00470	ENOG4105ETT	transcriptional Regulator, LysR family
C7S18_00485	ENOG4108M0H	Extracellular lipase
C7S18_00495	ENOG4105D25	secreted protein
C7S18_00505	ENOG4105EYF	MMPL domain protein
C7S18_00530	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_00535	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C7S18_00540	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
C7S18_00570	ENOG41077A9	carbonic anhydrase
C7S18_00600	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C7S18_00700	ENOG4105D9P	serine threonine protein kinase
C7S18_00730	ENOG4105C1J	atp-dependent rna helicase
C7S18_00735	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
C7S18_00760	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C7S18_00770	ENOG4105T95	Thiol disulfide interChange protein
C7S18_00780	ENOG410756H	nucleotidyltransferase
C7S18_00800	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C7S18_00805	ENOG4107TDE	lipolytic protein G-D-S-L family
C7S18_00815	ENOG4105D9P	serine threonine protein kinase
C7S18_00845	ENOG4105D9P	serine threonine protein kinase
C7S18_00860	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C7S18_00865	ENOG4105DUX	Transporter
C7S18_00870	ENOG4105CYC	Transferase
C7S18_00880	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C7S18_00885	ENOG4105K63	Thioredoxin
C7S18_00890	ENOG4105EUB	pirin domain protein
C7S18_00900	ENOG4105BZU	Histidine kinase
C7S18_00905	ENOG4105BZU	Histidine kinase
C7S18_00910	ENOG4105BZU	Histidine kinase
C7S18_00955	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C7S18_00960	ENOG4105E0C	molybdate abc transporter
C7S18_00965	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C7S18_01015	ENOG4107QI1	Mate efflux family protein
C7S18_01020	ENOG4105D07	Signal peptide peptidase, SppA
C7S18_01030	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
C7S18_01065	ENOG4108M3R	transcriptional activator CadC
C7S18_01100	ENOG4105KDM	Diguanylate cyclase with gaf sensor
C7S18_01130	ENOG4108YP4	Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues (By similarity)
C7S18_01145	ENOG41080HT	Transcriptional regulator, arsr family
C7S18_01155	ENOG4105XEA	Tetr family transcriptional regulator
C7S18_01170	ENOG4108DT4	serine threonine protein kinase
C7S18_01185	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C7S18_01200	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C7S18_01210	ENOG4105BZU	Histidine kinase
C7S18_01220	ENOG4108YXA	Membrane
C7S18_01230	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
C7S18_01235	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C7S18_01250	ENOG4105CHU	acetyl-coa acetyltransferase
C7S18_01255	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C7S18_01260	ENOG4105DGW	oligopeptidase A
C7S18_01265	ENOG4108V6E	Cell division protein mraZ
C7S18_01270	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C7S18_01275	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C7S18_01280	ENOG4105CJN	penicillin-binding protein
C7S18_01285	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C7S18_01290	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
C7S18_01295	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C7S18_01305	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C7S18_01310	ENOG4105DFU	Cell wall formation (By similarity)
C7S18_01315	ENOG4105CPF	Cell wall formation (By similarity)
C7S18_01320	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C7S18_01325	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C7S18_01330	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C7S18_01335	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C7S18_01345	ENOG4105DR5	peptidase
C7S18_01350	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C7S18_01355	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C7S18_01385	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C7S18_01390	ENOG4105C7S	Dehydrogenase
C7S18_01410	ENOG4105D9P	serine threonine protein kinase
C7S18_01430	ENOG4105FEU	K -dependent Na -Ca exchanger
C7S18_01445	ENOG4105BZU	Histidine kinase
C7S18_01450	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_01475	ENOG4105FE9	pseudouridine synthase
C7S18_01490	ENOG4105C03	ribonuclease
C7S18_01495	ENOG4105EI2	Pseudouridine synthase
C7S18_01525	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C7S18_01535	ENOG4105F7P	transcriptional regulator AsnC family
C7S18_01545	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
C7S18_01550	ENOG4105IFJ	Histidine kinase
C7S18_01560	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C7S18_01570	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C7S18_01575	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C7S18_01580	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C7S18_01585	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C7S18_01590	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C7S18_01605	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C7S18_01615	ENOG4105M3Z	response regulator
C7S18_01650	ENOG4107GRR	phosphate transport regulator
C7S18_01655	ENOG4105CJ3	phosphate transporter
C7S18_01660	ENOG4108Z6B	deaminase
C7S18_01665	ENOG4105CVA	phosphate
C7S18_01670	ENOG4105C2M	dna polymerase I
C7S18_01695	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C7S18_01700	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C7S18_01720	ENOG4108AHD	Transcriptional regulator
C7S18_01725	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C7S18_01730	ENOG4105ECQ	AraC Family Transcriptional Regulator
C7S18_01765	ENOG4108Z1B	Cyclase dehydrase
C7S18_01770	ENOG4105VDB	UPF0125 protein
C7S18_01775	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C7S18_01780	ENOG41090R7	Ferric uptake
C7S18_01805	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C7S18_01810	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C7S18_01815	ENOG4105KQC	Competence protein
C7S18_01835	ENOG4105EHV	domain protein
C7S18_01840	ENOG4105C2D	reductase
C7S18_01845	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C7S18_01855	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C7S18_01860	ENOG4107ZQV	short-chain dehydrogenase reductase
C7S18_01875	ENOG4105DDG	Cyanophycinase
C7S18_01880	ENOG4105EJQ	L-serine dehydratase
C7S18_01895	ENOG4105W0E	50S ribosomal protein L33
C7S18_01900	ENOG4105KDC	50s ribosomal protein l28
C7S18_01910	ENOG4105BZJ	Electron transfer flavoprotein
C7S18_01915	ENOG4105C10	Electron transfer flavoprotein
C7S18_01925	ENOG4105K63	Thioredoxin
C7S18_01930	ENOG4105C1J	atp-dependent rna helicase
C7S18_01955	ENOG4105HF0	Membrane
C7S18_01990	ENOG4106032	Glutathionylspermidine synthase
C7S18_01995	ENOG4105CBC	glutamate synthase
C7S18_02015	ENOG4105C1G	acyl-Coa dehydrogenase
C7S18_02025	ENOG4105DYB	Isoaspartyl dipeptidase
C7S18_02035	ENOG4105CSU	acyl-Coa dehydrogenase
C7S18_02050	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C7S18_02055	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C7S18_02060	ENOG4105KNE	Phosphatidate cytidylyltransferase
C7S18_02065	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C7S18_02070	ENOG4105DZP	Membrane-associated zinc metalloprotease
C7S18_02075	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7S18_02085	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C7S18_02095	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C7S18_02100	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C7S18_02130	ENOG4105VEQ	Cold shock protein
C7S18_02145	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C7S18_02165	ENOG4105ECQ	AraC Family Transcriptional Regulator
C7S18_02170	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
C7S18_02230	ENOG4105D9P	serine threonine protein kinase
C7S18_02240	ENOG4108UHU	Aldolase
C7S18_02250	ENOG4105C01	Dihydroxy-acid dehydratase
C7S18_02315	ENOG4106TD9	Diguanylate cyclase
C7S18_02325	ENOG4108YIQ	Alpha beta hydrolase
C7S18_02330	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C7S18_02340	ENOG4108JJ7	ABC transporter
C7S18_02355	ENOG4105DHP	deoxycytidine triphosphate deaminase
C7S18_02375	ENOG4107RDJ	Sulfotransferase
C7S18_02380	ENOG4105BZU	Histidine kinase
C7S18_02385	ENOG4105C6K	Malic enzyme
C7S18_02395	ENOG4105D44	asparaginase
C7S18_02400	ENOG4105D4P	Coproporphyrinogen iii oxidase
C7S18_02410	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C7S18_02415	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C7S18_02420	ENOG4105CDU	Replicative dna helicase
C7S18_02445	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
C7S18_02450	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
C7S18_02465	ENOG4108EC8	DNA internalization-related competence protein ComEC
C7S18_02470	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C7S18_02475	ENOG4105D60	lipoprotein releasing system transmembrane protein
C7S18_02480	ENOG4105C84	Histidine ammonia-lyase
C7S18_02500	ENOG4105KHC	sulfurtransferase
C7S18_02510	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C7S18_02525	ENOG4105CYB	regulatoR
C7S18_02535	ENOG4105E0Y	RtcB Protein
C7S18_02550	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C7S18_02570	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
C7S18_02580	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C7S18_02640	ENOG4108NEV	two component transcriptional regulator, LytTR family
C7S18_02645	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C7S18_02650	ENOG4105DFH	Transport of potassium into the cell (By similarity)
C7S18_02655	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C7S18_02695	ENOG4105D22	carbon starvation protein
C7S18_02705	ENOG4105EYW	Ion transport protein
C7S18_02710	ENOG4105EWT	decarboxylase family
C7S18_02715	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
C7S18_02725	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C7S18_02755	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C7S18_02760	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C7S18_02765	ENOG4105K5M	30s ribosomal protein S16
C7S18_02770	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7S18_02775	ENOG4106KVJ	cytochrome C assembly protein
C7S18_02790	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C7S18_02795	ENOG4106RE7	Cytochrome
C7S18_02800	ENOG4106RE7	Cytochrome
C7S18_02805	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C7S18_02820	ENOG4105C3M	thioredoxin reductase
C7S18_02825	ENOG4105CNU	cell division protein FtsK
C7S18_02830	ENOG4105E39	Enoyl-CoA hydratase
C7S18_02855	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C7S18_02870	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C7S18_02885	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C7S18_02925	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C7S18_02945	ENOG4108IPT	Naphthoate synthase
C7S18_03005	ENOG4105C4R	Atp-dependent dna helicase
C7S18_03010	ENOG4105CI2	imidazolone-5-propionate hydrolase
C7S18_03020	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C7S18_03025	ENOG4105BZS	acriflavin resistance protein
C7S18_03050	ENOG4105VNG	YcgL domain-containing protein
C7S18_03065	ENOG4105C75	arginyL-tRNA synthetase
C7S18_03070	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C7S18_03075	ENOG4105D9N	nucleoside
C7S18_03105	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7S18_03115	ENOG4105E9H	Lytic Murein transglycosylase
C7S18_03120	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
C7S18_03155	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C7S18_03175	ENOG4108V5V	Serine Threonine protein kinase
C7S18_03200	ENOG4105NRA	50s ribosomal protein l31 type b
C7S18_03205	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
C7S18_03210	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
C7S18_03215	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C7S18_03220	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
C7S18_03240	ENOG4105DHG	Allantoate amidinohydrolase
C7S18_03245	ENOG4108IUZ	ABC transporter
C7S18_03260	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
C7S18_03265	ENOG4105C2X	Arabinose 5-phosphate isomerase
C7S18_03275	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C7S18_03290	ENOG4108Z4X	TRANSCRIPTIONal
C7S18_03315	ENOG4105DZC	cytosine deaminase
C7S18_03320	ENOG4105C26	Dehydrogenase
C7S18_03325	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
C7S18_03365	ENOG4105BZ8	glutamate synthase
C7S18_03380	ENOG4107SJI	Dehydrogenase
C7S18_03385	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
C7S18_03400	ENOG4105BZU	Histidine kinase
C7S18_03415	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C7S18_03425	ENOG4105CP2	von willebrand factor, type a
C7S18_03430	ENOG4108IUX	(ABC) transporter
C7S18_03435	ENOG4105RHA	ABC transporter, permease
C7S18_03440	ENOG4105CEN	a g-specific adenine glycosylase
C7S18_03450	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C7S18_03455	ENOG4106H78	methyltransferase
C7S18_03460	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C7S18_03470	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C7S18_03510	ENOG4105CHR	reductase
C7S18_03515	ENOG4105CIS	alcohol dehydrogenase
C7S18_03530	ENOG4107XAN	XdhC and CoxI family
C7S18_03545	ENOG4105CNG	UPF0061 protein
C7S18_03550	ENOG4105BZU	Histidine kinase
C7S18_03555	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
C7S18_03560	ENOG4105DIJ	Phosphoethanolamine transferase
C7S18_03570	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_03590	ENOG4108JDX	DNA polymerase iii, epsilon subunit
C7S18_03595	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C7S18_03605	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C7S18_03625	ENOG4105C0B	DNA polymerase III (alpha subunit)
C7S18_03630	ENOG4105C26	Dehydrogenase
C7S18_03645	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C7S18_03650	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C7S18_03655	ENOG4107YPT	transcriptional regulator
C7S18_03680	ENOG4105DHJ	ABC, transporter
C7S18_03695	ENOG410645S	MarR family Transcriptional regulator
C7S18_03715	ENOG4105CGY	Dna recombination protein
C7S18_03720	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
C7S18_03770	ENOG4105CJW	magnesium transporter
C7S18_03780	ENOG4105CMR	udp-glucose 4-epimerase
C7S18_03840	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C7S18_03845	ENOG4108VIA	integral membrane protein
C7S18_03850	ENOG4105II7	pyrroline-5-carboxylate reductase
C7S18_03855	ENOG4105DFA	alanine racemase domain protein
C7S18_03860	ENOG4105CZX	twitching motility protein
C7S18_03870	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C7S18_03885	ENOG4108HMX	isocitrate dehydrogenase (NADP)
C7S18_03890	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C7S18_03915	ENOG4105DHJ	ABC, transporter
C7S18_03925	ENOG4108HM4	ABC transporter
C7S18_03930	ENOG4105BZU	Histidine kinase
C7S18_03945	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
C7S18_03960	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C7S18_03985	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C7S18_03995	ENOG4108HRK	Histidine kinase
C7S18_04000	ENOG4105DY9	regulatoR
C7S18_04005	ENOG4105CBN	LysR family transcriptional regulator
C7S18_04010	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C7S18_04055	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C7S18_04095	ENOG4107RE3	peptidase, S41
C7S18_04100	ENOG4107QM5	aconitate hydratase
C7S18_04105	ENOG4108K8S	endonuclease I
C7S18_04130	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C7S18_04145	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C7S18_04150	ENOG4105W8H	transhydrogenase (subunit alpha
C7S18_04155	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C7S18_04165	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C7S18_04200	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C7S18_04225	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
C7S18_04245	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C7S18_04250	ENOG4105DXX	methyltransferase
C7S18_04265	ENOG4105C26	Dehydrogenase
C7S18_04270	ENOG4105D38	putrescine abc transporter
C7S18_04275	ENOG4105F38	ABC transporter, permease
C7S18_04280	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C7S18_04290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C7S18_04300	ENOG4108Z86	Glutamine amidotransferase
C7S18_04305	ENOG4105CFQ	glutamine synthetase
C7S18_04310	ENOG4107RK2	ADP-ribose diphosphatase NudE
C7S18_04315	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
C7S18_04320	ENOG4105DXN	mazG family
C7S18_04325	ENOG4105D9P	serine threonine protein kinase
C7S18_04335	ENOG4105D9P	serine threonine protein kinase
C7S18_04340	ENOG4105D9P	serine threonine protein kinase
C7S18_04395	ENOG4105D5P	Methylmalonyl-coA mutase
C7S18_04405	ENOG4107RRE	RNA-directed DNA polymerase
C7S18_04430	ENOG4105M6F	mutator MutT protein
C7S18_04460	ENOG4105F2I	Transposase
C7S18_04515	ENOG4105F2I	Transposase
C7S18_04610	ENOG4105D9P	serine threonine protein kinase
C7S18_04620	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_04690	ENOG4107QS8	(LipO)protein
C7S18_04720	ENOG4108DT4	serine threonine protein kinase
C7S18_04755	ENOG4105D9P	serine threonine protein kinase
C7S18_04805	ENOG4105MYN	Zinc uptake regulation protein
C7S18_04820	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C7S18_04825	ENOG4105CUX	Signal transduction histidine kinase
C7S18_04830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C7S18_04840	ENOG4105DUX	Transporter
C7S18_04845	ENOG4107GFK	fumarate
C7S18_04885	ENOG4105D9P	serine threonine protein kinase
C7S18_04895	ENOG4105D9P	serine threonine protein kinase
C7S18_04915	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C7S18_04925	ENOG4108Z0R	Transferase
C7S18_04935	ENOG4105BZU	Histidine kinase
C7S18_04945	ENOG4105DVT	helicase
C7S18_04955	ENOG4105BZ4	penicillin-binding protein
C7S18_04960	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C7S18_04970	ENOG4105K9H	YciI-like protein
C7S18_04980	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
C7S18_04985	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
C7S18_04990	ENOG4105FE9	pseudouridine synthase
C7S18_04995	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C7S18_05000	ENOG4105NWN	ApaG protein
C7S18_05015	ENOG4108URH	decarboxylase
C7S18_05020	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
C7S18_05030	ENOG4107XZ0	Peptidase M50
C7S18_05050	ENOG4105D9P	serine threonine protein kinase
C7S18_05075	ENOG4105C58	cytochrome c oxidase accessory protein ccog
C7S18_05100	ENOG4105D98	threonine synthase
C7S18_05110	ENOG4105CFH	Aspartokinase
C7S18_05115	ENOG4105CAT	Cytidine monophosphate kinase
C7S18_05120	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C7S18_05125	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C7S18_05135	ENOG4105CFV	Tetratricopeptide repeat protein
C7S18_05145	ENOG4105D9P	serine threonine protein kinase
C7S18_05155	ENOG4105CI2	imidazolone-5-propionate hydrolase
C7S18_05205	ENOG4108V06	Glutathione peroxidase
C7S18_05210	ENOG4105KG3	cytidine deaminase
C7S18_05215	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C7S18_05235	ENOG4105D8V	Glucose sorbosone dehydrogenase
C7S18_05250	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C7S18_05255	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
C7S18_05275	ENOG4108ADH	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
C7S18_05310	ENOG4107TK4	histidinol-phosphate phosphatase
C7S18_05325	ENOG4105E4C	Lytic transglycosylase catalytic
C7S18_05355	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
C7S18_05365	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C7S18_05370	ENOG4105CRQ	synthase (Component I)
C7S18_05375	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
C7S18_05380	ENOG4105HHA	aminodeoxychorismate lyase
C7S18_05385	ENOG4107QRG	dna polymerase iii
C7S18_05425	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C7S18_05505	ENOG4105C7F	AcnD-accessory protein PrpF
C7S18_05510	ENOG4108I0Z	Aconitate hydratase
C7S18_05540	ENOG4105M15	transport protein ExbD
C7S18_05545	ENOG4105BZ1	(ABC) transporter
C7S18_05550	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C7S18_05560	ENOG4105KJF	protein tyrosine phosphatase
C7S18_05570	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C7S18_05595	ENOG4105DFP	Integrase
C7S18_05640	ENOG4108ZGC	gaf domain protein
C7S18_05655	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C7S18_05665	ENOG4105DZ1	carboxypeptidase
C7S18_05675	ENOG4105CVE	Lytic murein transglycosylase
C7S18_05680	ENOG4105QYV	Membrane
C7S18_05690	ENOG4108UVJ	appr-1-p processing domain protein
C7S18_05695	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C7S18_05700	ENOG4108R5S	membrane
C7S18_05760	ENOG4105EAH	synthase
C7S18_05770	ENOG4108UUM	single-stranded DNA-binding protein
C7S18_05785	ENOG4105D9P	serine threonine protein kinase
C7S18_05800	ENOG4108KPZ	tonB-dependent Receptor
C7S18_05815	ENOG4105CI2	imidazolone-5-propionate hydrolase
C7S18_05825	ENOG4107QR8	Thioredoxin
C7S18_05855	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C7S18_05860	ENOG4105VGS	50s ribosomal protein l32
C7S18_05865	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C7S18_05870	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C7S18_05875	ENOG4105CHR	reductase
C7S18_05895	ENOG4105CV6	ABC transporter, permease
C7S18_05900	ENOG4108I0Y	(ABC) transporter
C7S18_05905	ENOG4108UJV	acyl-CoA thioesterase i
C7S18_05915	ENOG4105CH2	amidohydrolase
C7S18_05920	ENOG4106V2I	dimethylaminohydrolase
C7S18_05955	ENOG4105DBV	ornithine carbamoyltransferase
C7S18_05960	ENOG4105CDH	Citrulline--aspartate ligase
C7S18_05970	ENOG4105CAS	nag kinase
C7S18_05975	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C7S18_05980	ENOG4105CH7	arginosuccinase
C7S18_05985	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C7S18_05990	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C7S18_06025	ENOG4105F2I	Transposase
C7S18_06330	ENOG4105CH2	amidohydrolase
C7S18_06350	ENOG4105F2I	Transposase
C7S18_06360	ENOG4108HMN	Caspase domain
C7S18_06455	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
C7S18_06460	ENOG4105DY8	decarboxylase
C7S18_06475	ENOG4108IAB	Phoh family
C7S18_06485	ENOG4107TUS	Dihydrodipicolinate synthase
C7S18_06495	ENOG4108Z4U	Ferredoxin
C7S18_06510	ENOG4105DJ0	Poly(A) Polymerase
C7S18_06515	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7S18_06520	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C7S18_06525	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C7S18_06535	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C7S18_06545	ENOG4105C26	Dehydrogenase
C7S18_06550	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C7S18_06565	ENOG4105D7A	ATP-binding protein
C7S18_06570	ENOG4108RRZ	Transcription elongation factor GreB
C7S18_06585	ENOG4107R39	(ABC) transporter
C7S18_06595	ENOG4105CSU	acyl-Coa dehydrogenase
C7S18_06615	ENOG4105C26	Dehydrogenase
C7S18_06620	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C7S18_06625	ENOG4105C9K	Endothelin-converting enzyme 1
C7S18_06630	ENOG4105C3R	Methionine synthase
C7S18_06670	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C7S18_06675	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C7S18_06680	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C7S18_06685	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C7S18_06695	ENOG4105DDQ	anthranilate synthase
C7S18_06700	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C7S18_06705	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C7S18_06715	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C7S18_06720	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C7S18_06735	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C7S18_06740	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C7S18_06745	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C7S18_06755	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C7S18_06760	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
C7S18_06765	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C7S18_06770	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C7S18_06775	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
C7S18_06800	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C7S18_06810	ENOG4105DY8	decarboxylase
C7S18_06815	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C7S18_06820	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C7S18_06825	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C7S18_06835	ENOG4105EKE	dihydroorotase
C7S18_06890	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C7S18_06895	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C7S18_06900	ENOG4108UM1	dedA family
C7S18_06905	ENOG4108K5P	(LipO)protein
C7S18_06920	ENOG4105DA5	(ABC) transporter
C7S18_06935	ENOG41062JF	Transcriptional regulator
C7S18_06950	ENOG4105PDP	Short chain dehydrogenase
C7S18_06960	ENOG4105EYW	Ion transport protein
C7S18_06980	ENOG4105C7K	acetolactate synthase
C7S18_06990	ENOG4105D9P	serine threonine protein kinase
C7S18_07000	ENOG4108DT4	serine threonine protein kinase
C7S18_07005	ENOG4105NAF	rna polymerase sigma factor
C7S18_07020	ENOG4108UAJ	Transcriptional regulator
C7S18_07025	ENOG4107QI1	Mate efflux family protein
C7S18_07030	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7S18_07035	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C7S18_07050	ENOG4105DN3	alpha-2-macroglobulin domain protein
C7S18_07055	ENOG4108JQB	penicillin-binding protein 1C
C7S18_07065	ENOG4108JSS	Haloalkane dehalogenase
C7S18_07070	ENOG4105DHQ	Histidine kinase
C7S18_07090	ENOG4105C5H	ABC transporter
C7S18_07095	ENOG4105BZU	Histidine kinase
C7S18_07110	ENOG4105CPP	Dehydrogenase, E1 component
C7S18_07115	ENOG4107QSN	dihydrolipoamide acetyltransferase
C7S18_07125	ENOG4108HPI	phosphatidate Cytidylyltransferase
C7S18_07140	ENOG41077RS	Phosphatase
C7S18_07145	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
C7S18_07150	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
C7S18_07155	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
C7S18_07160	ENOG4107IFA	Lipase (EC 3.1.1.3)
C7S18_07190	ENOG4105EFZ	amidohydrolase
C7S18_07205	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C7S18_07230	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C7S18_07250	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C7S18_07260	ENOG4108ESX	Receptor
C7S18_07270	ENOG4107E2E	PKHD-type hydroxylase
C7S18_07280	ENOG4105CUB	amino acid
C7S18_07295	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C7S18_07305	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
C7S18_07325	ENOG4105E33	succinate dehydrogenase
C7S18_07355	ENOG4108SA1	esterase
C7S18_07360	ENOG4107QJE	Chromosome Partitioning Protein
C7S18_07365	ENOG4105FA0	parb-like partition protein
C7S18_07375	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C7S18_07390	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7S18_07395	ENOG4105CFG	Acts as a chaperone (By similarity)
C7S18_07410	ENOG4105RHY	Pfam:UPF0157
C7S18_07425	ENOG4105CC0	LysR family Transcriptional regulator
C7S18_07460	ENOG4105EZE	Cupin 4 family protein
C7S18_07470	ENOG4108WWZ	General secretion pathway protein J
C7S18_07475	ENOG4105X5Z	General secretion pathway protein I
C7S18_07485	ENOG4108VAU	general secretion pathway protein G
C7S18_07495	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C7S18_07500	ENOG4105UGU	tonB-dependent Receptor
C7S18_07510	ENOG4108YZA	Nitrogen regulatory protein pii
C7S18_07515	ENOG4105BZU	Histidine kinase
C7S18_07530	ENOG4105CKW	Inner membrane protein yedI
C7S18_07540	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C7S18_07555	ENOG4108RAC	Rubrerythrin
C7S18_07560	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C7S18_07565	ENOG4105G5H	Membrane
C7S18_07570	ENOG4107QX8	SPFH domain, Band 7 family protein
C7S18_07595	ENOG4105D1S	lipid A biosynthesis
C7S18_07600	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C7S18_07620	ENOG4108Z03	MAF-like protein
C7S18_07635	ENOG4105KWW	Biogenesis protein
C7S18_07640	ENOG4107QX9	Thiol disulfide interChange protein
C7S18_07645	ENOG4105DA4	cytochrome c-type biogenesis protein
C7S18_07650	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
C7S18_07660	ENOG41060IM	Heme exporter protein
C7S18_07665	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
C7S18_07670	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
C7S18_07675	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_07680	ENOG4105CFH	Aspartokinase
C7S18_07690	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C7S18_07695	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
C7S18_07705	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C7S18_07710	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C7S18_07715	ENOG4108MN8	Membrane
C7S18_07720	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C7S18_07725	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
C7S18_07770	ENOG4105ETX	regulatoR
C7S18_07775	ENOG4105DHQ	Histidine kinase
C7S18_07780	ENOG4105CRQ	synthase (Component I)
C7S18_07800	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C7S18_07805	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C7S18_07815	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
C7S18_07820	ENOG4108Z7F	N-acetyltransferase
C7S18_07825	ENOG4105EYA	deoxyribonuclease
C7S18_07840	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C7S18_07845	ENOG4105SYT	Methylenetetrahydrofolate reductase
C7S18_07870	ENOG4108RU0	short-chain dehydrogenase reductase
C7S18_07875	ENOG4107ZSV	Receptor
C7S18_07915	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_07925	ENOG4105F2I	Transposase
C7S18_07930	ENOG41073TP	transcriptional regulator
C7S18_07935	ENOG4105DVE	abc transporter atp-binding protein
C7S18_07965	ENOG4105C19	ABC transporter
C7S18_07995	ENOG4105CEY	Amp-dependent synthetase and ligase
C7S18_08010	ENOG4106A3M	Cytochrome p-450
C7S18_08015	ENOG4107RCI	amp-dependent synthetase and ligase
C7S18_08035	ENOG4105CJ1	ABC, transporter
C7S18_08050	ENOG4105C19	ABC transporter
C7S18_08060	ENOG4107RBB	ABC transporter, permease
C7S18_08110	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C7S18_08140	ENOG41082BM	Transcriptional regulator, arsr family
C7S18_08160	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_08195	ENOG4105EGS	Mechanosensitive ion channel
C7S18_08205	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
C7S18_08250	ENOG4108HRK	Histidine kinase
C7S18_08255	ENOG4108VAC	response regulator
C7S18_08300	ENOG4105ESI	atpase involved in dna repair
C7S18_08370	ENOG4105GR3	Histidine kinase
C7S18_08390	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C7S18_08445	ENOG4105C8Y	Acetylornithine aminotransferase
C7S18_08455	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C7S18_08460	ENOG4105CHR	reductase
C7S18_08485	ENOG4105GAV	receptor
C7S18_08515	ENOG4108IJF	Heavy metal efflux pump, CzcA
C7S18_08520	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C7S18_08575	ENOG4107SJW	iron permease, FTR1
C7S18_08730	ENOG4108IQE	Amp-dependent synthetase and ligase
C7S18_08740	ENOG4105UBK	short-chain dehydrogenase reductase
C7S18_08750	ENOG4108VAC	response regulator
C7S18_08755	ENOG4108HRK	Histidine kinase
C7S18_08775	ENOG4105E18	UPF0276 protein
C7S18_08800	ENOG4108UYB	regulatoR
C7S18_08820	ENOG4107EFQ	arachidonate 15-lipoxygenase
C7S18_08845	ENOG4105CPQ	Dehydrogenase
C7S18_08860	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C7S18_08865	ENOG4105EB3	Histidine kinase
C7S18_08900	ENOG4105KAV	tspo and mbr like protein
C7S18_08905	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C7S18_08920	ENOG4105BZN	citrate synthase
C7S18_08930	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C7S18_08935	ENOG4105C8S	subunit m
C7S18_08940	ENOG4105D65	subunit l
C7S18_08945	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C7S18_08950	ENOG4105DF2	NADH dehydrogenase subunit j
C7S18_08955	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C7S18_08960	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C7S18_08970	ENOG4107QIZ	NADH dehydrogenase
C7S18_08980	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C7S18_08985	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C7S18_08990	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C7S18_08995	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C7S18_09010	ENOG4105CP7	Triose-phosphate isomerase
C7S18_09015	ENOG4107FW0	short-chain dehydrogenase reductase
C7S18_09025	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C7S18_09045	ENOG4105C26	Dehydrogenase
C7S18_09050	ENOG4107VRI	Transcriptional regulator
C7S18_09055	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C7S18_09060	ENOG4105DCF	alanine dehydrogenase
C7S18_09065	ENOG4105CYW	agmatinase
C7S18_09090	ENOG41080IJ	Diacylglycerol kinase
C7S18_09095	ENOG4105EE5	Membrane protein terC
C7S18_09110	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
C7S18_09115	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
C7S18_09125	ENOG4108QER	Adenylate cyclase
C7S18_09130	ENOG4107QP8	phosphohexose isomerase
C7S18_09135	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C7S18_09145	ENOG4108JU5	Magnesium and cobalt efflux protein
C7S18_09150	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C7S18_09160	ENOG4105C9A	Phoh family
C7S18_09170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C7S18_09175	ENOG4107QZF	nitrite reductase NADPH large subunit
C7S18_09180	ENOG4105C5Q	Transcriptional regulator
C7S18_09195	ENOG4105ESV	Glycosyl transferase, family 4
C7S18_09200	ENOG4105C30	Nad-dependent epimerase dehydratase
C7S18_09205	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
C7S18_09210	ENOG4105CMR	udp-glucose 4-epimerase
C7S18_09215	ENOG4108IAJ	Nad-dependent epimerase dehydratase
C7S18_09220	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C7S18_09240	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C7S18_09245	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C7S18_09260	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C7S18_09265	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C7S18_09270	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C7S18_09275	ENOG4105D9P	serine threonine protein kinase
C7S18_09280	ENOG4107TH8	cina domain protein
C7S18_09285	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C7S18_09300	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C7S18_09310	ENOG4108S01	response regulator
C7S18_09315	ENOG4105BZU	Histidine kinase
C7S18_09320	ENOG4105C8Y	Acetylornithine aminotransferase
C7S18_09330	ENOG4108DT4	serine threonine protein kinase
C7S18_09345	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C7S18_09350	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C7S18_09355	ENOG4105D06	uba thif-type nad fad binding protein
C7S18_09380	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C7S18_09540	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
C7S18_09585	ENOG4105D25	secreted protein
C7S18_09650	ENOG4105EJ2	Transcriptional regulator
C7S18_09665	ENOG41082BM	Transcriptional regulator, arsr family
C7S18_09690	ENOG4105EBR	Carboxylesterase
C7S18_09760	ENOG4105DSQ	Nitric oxide reductase
C7S18_09810	ENOG4105NX3	Membrane
C7S18_09830	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C7S18_09835	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C7S18_09840	ENOG4105BZU	Histidine kinase
C7S18_09865	ENOG4105WKW	Pfam:DUF1458
C7S18_09875	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C7S18_09880	ENOG4105D49	3-dehydroquinate synthase
C7S18_09915	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C7S18_09925	ENOG4105C72	UPF0176 protein
C7S18_09935	ENOG4105DR9	pseudouridine synthase
C7S18_09940	ENOG4105ENE	Histidine kinase
C7S18_09945	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_09950	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_09955	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C7S18_09960	ENOG4105YK5	50S ribosomal protein L36
C7S18_09965	ENOG4105D6S	protein involved in catabolism of external DNA
C7S18_09970	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C7S18_09985	ENOG4105C0A	alcohol dehydrogenase
C7S18_09990	ENOG4105C26	Dehydrogenase
C7S18_10000	ENOG4105CUB	amino acid
C7S18_10015	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C7S18_10020	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C7S18_10025	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C7S18_10030	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C7S18_10035	ENOG4105KUZ	arsenate reductase
C7S18_10040	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
C7S18_10060	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C7S18_10070	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
C7S18_10080	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C7S18_10090	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C7S18_10100	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C7S18_10105	ENOG4105C3G	gtp-binding protein
C7S18_10120	ENOG4105F2I	Transposase
C7S18_10130	ENOG4107R5S	dna adenine
C7S18_10145	ENOG4105EQR	Transposase IS116 IS110 IS902
C7S18_10205	ENOG4105F2I	Transposase
C7S18_10315	ENOG4105F2I	Transposase
C7S18_10360	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_10375	ENOG4107RDJ	Sulfotransferase
C7S18_10440	ENOG4107RBB	ABC transporter, permease
C7S18_10445	ENOG4105C19	ABC transporter
C7S18_10450	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C7S18_10525	ENOG4107EFQ	arachidonate 15-lipoxygenase
C7S18_10570	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
C7S18_10575	ENOG4105BZF	Glycosyl transferase (Group 1
C7S18_10585	ENOG4105CHH	sulfate transporter
C7S18_10600	ENOG4105D9P	serine threonine protein kinase
C7S18_10610	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C7S18_10620	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C7S18_10625	ENOG4105CHV	Transcription elongation factor NusA
C7S18_10630	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C7S18_10645	ENOG4105CR4	methylisocitrate lyase
C7S18_10655	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C7S18_10695	ENOG4105CY0	Metallo-Beta-Lactamase
C7S18_10705	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C7S18_10710	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
C7S18_10715	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C7S18_10720	ENOG4105W4W	Transcriptional regulator
C7S18_10735	ENOG4105BZS	acriflavin resistance protein
C7S18_10745	ENOG4105BZU	Histidine kinase
C7S18_10750	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C7S18_10755	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C7S18_10765	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C7S18_10770	ENOG41075W9	High frequency lysogenization protein HflD homolog
C7S18_10780	ENOG4105C31	Tryptophanyl-tRNA synthetase
C7S18_10795	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C7S18_10810	ENOG4105VJY	transcriptional regulator
C7S18_10815	ENOG4105NNS	Autoinducer synthesis protein
C7S18_10820	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C7S18_10825	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C7S18_10840	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C7S18_10860	ENOG4108R3D	Electron transport complex
C7S18_10865	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C7S18_10870	ENOG4107QTF	adenylosuccinate lyase
C7S18_10875	ENOG4105K8N	protein family UPF0079, ATPase
C7S18_10880	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C7S18_10895	ENOG4105BZU	Histidine kinase
C7S18_10905	ENOG4105D9P	serine threonine protein kinase
C7S18_10930	ENOG4106WTF	Glycosyl transferase, family 2
C7S18_10955	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C7S18_10975	ENOG4105CUZ	uba thif-type nad fad binding protein
C7S18_10980	ENOG4105KSC	Transcriptional regulator, TraR DksA family
C7S18_10985	ENOG4105EB3	Histidine kinase
C7S18_10990	ENOG4107RAQ	aminopeptidase
C7S18_11000	ENOG4105BZU	Histidine kinase
C7S18_11020	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_11025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_11065	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C7S18_11070	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C7S18_11080	ENOG4105BZ8	glutamate synthase
C7S18_11085	ENOG4105CBC	glutamate synthase
C7S18_11110	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C7S18_11115	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C7S18_11130	ENOG4105CHM	Aminotransferase
C7S18_11140	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
C7S18_11160	ENOG4105DR5	peptidase
C7S18_11165	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C7S18_11170	ENOG4105D52	delta-aminolevulinic acid dehydratase
C7S18_11175	ENOG4105CQ7	ATP-dependent helicase
C7S18_11205	ENOG4107QKG	PfaD family
C7S18_11250	ENOG4105D05	Receptor
C7S18_11270	ENOG4105CSA	Coproporphyrinogen iii oxidase
C7S18_11275	ENOG4105Y3E	Modulates RecA activity (By similarity)
C7S18_11295	ENOG4105C0D	helicase
C7S18_11335	ENOG4107R3N	Filamentation induced by cAMP protein fic
C7S18_11355	ENOG4105C0D	helicase
C7S18_11385	ENOG4105CFG	Acts as a chaperone (By similarity)
C7S18_11420	ENOG4105C72	UPF0176 protein
C7S18_11425	ENOG4105D3G	Pseudouridine synthase
C7S18_11450	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C7S18_11470	ENOG4105DMF	Dehydrogenase
C7S18_11485	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C7S18_11495	ENOG4105VW4	glutaredoxin 3
C7S18_11500	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
C7S18_11515	ENOG4105ERG	peptidase m48, ste24p
C7S18_11520	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C7S18_11525	ENOG4105BZU	Histidine kinase
C7S18_11540	ENOG4105DTQ	mandelate racemase muconate lactonizing
C7S18_11550	ENOG4105CK2	sodium dicarboxylate symporter
C7S18_11560	ENOG4105C03	ribonuclease
C7S18_11575	ENOG4105VEQ	Cold shock protein
C7S18_11595	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C7S18_11600	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C7S18_11605	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C7S18_11615	ENOG4105C3F	Signal peptidase i
C7S18_11625	ENOG4105C0H	protease
C7S18_11640	ENOG4105EMN	RNA polymerase sigma factor
C7S18_11645	ENOG4105BZU	Histidine kinase
C7S18_11655	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C7S18_11660	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
C7S18_11700	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
C7S18_11715	ENOG4105EX9	Membrane
C7S18_11740	ENOG4105C1G	acyl-Coa dehydrogenase
C7S18_11750	ENOG4107RIQ	Sulfate adenylate transferase
C7S18_11755	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C7S18_11760	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C7S18_11765	ENOG4105BZU	Histidine kinase
C7S18_11770	ENOG4105CHU	acetyl-coa acetyltransferase
C7S18_11780	ENOG4107QX3	carboxylase
C7S18_11805	ENOG4105DB1	molybdopterin oxidoreductase
C7S18_11835	ENOG4108IG5	Transcriptional regulator
C7S18_11840	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C7S18_11880	ENOG4105WMR	Protein CrcB homolog
C7S18_11920	ENOG4105NA0	Transcriptional regulator
C7S18_11950	ENOG4105C08	Histidine kinase
C7S18_11955	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C7S18_11960	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C7S18_11965	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C7S18_11975	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C7S18_12035	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C7S18_12075	ENOG4105D9P	serine threonine protein kinase
C7S18_12085	ENOG4105HDK	L-asparaginase
C7S18_12095	ENOG4105C0H	protease
C7S18_12100	ENOG4107RZC	phospholipase d
C7S18_12330	ENOG4106YXT	transposase
C7S18_12370	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_12400	ENOG4108UVJ	appr-1-p processing domain protein
C7S18_12405	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_12420	ENOG41080HT	Transcriptional regulator, arsr family
C7S18_12425	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
C7S18_12460	ENOG4107QPV	Serine Threonine protein kinase
C7S18_12475	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C7S18_12480	ENOG4105DJF	DNA polymerase III, delta' subunit
C7S18_12490	ENOG4105C8T	Leucyl-tRNA synthetase
C7S18_12500	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C7S18_12520	ENOG4105E0F	Histidine kinase
C7S18_12525	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C7S18_12550	ENOG4105DWF	phosphomethylpyrimidine kinase
C7S18_12555	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
C7S18_12565	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C7S18_12575	ENOG4108RAV	Conserved protein
C7S18_12585	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C7S18_12595	ENOG4108JQ1	Dehydrogenase
C7S18_12600	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C7S18_12605	ENOG4107S4F	acyltransferase, ws dgat mgat
C7S18_12610	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C7S18_12630	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_12650	ENOG4105C01	Dihydroxy-acid dehydratase
C7S18_12655	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C7S18_12670	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C7S18_12675	ENOG4105C7B	Threonine dehydratase
C7S18_12690	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C7S18_12695	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C7S18_12705	ENOG4105C8U	phosphate abc transporter
C7S18_12710	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
C7S18_12725	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C7S18_12730	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C7S18_12735	ENOG4107QJR	hflk protein
C7S18_12740	ENOG4105EPW	hflc protein
C7S18_12780	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C7S18_12795	ENOG4105CPQ	Dehydrogenase
C7S18_12805	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C7S18_12810	ENOG4105MSY	salicylate hydroxylase
C7S18_12815	ENOG4105D0A	hydroxylase
C7S18_12825	ENOG4108WBT	adenosyltransferase
C7S18_12840	ENOG4105C1G	acyl-Coa dehydrogenase
C7S18_12855	ENOG4105EIF	outer membrane protein W
C7S18_12860	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C7S18_12870	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C7S18_12885	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
C7S18_12910	ENOG4105FDR	Membrane
C7S18_12920	ENOG4105CK2	sodium dicarboxylate symporter
C7S18_12925	ENOG4105DGI	Alkaline phosphatase
C7S18_12945	ENOG4105CZX	twitching motility protein
C7S18_12975	ENOG4105NQG	DoxX
C7S18_12990	ENOG4108JQB	penicillin-binding protein 1C
C7S18_12995	ENOG4105DFG	type I secretion outer membrane protein
C7S18_13000	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C7S18_13010	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C7S18_13015	ENOG4108IG5	Transcriptional regulator
C7S18_13025	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C7S18_13040	ENOG4105FUY	alpha subunit
C7S18_13045	ENOG4105EXC	Acyl-transferase
C7S18_13080	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C7S18_13090	ENOG4105F8C	transglutaminase domain-containing protein
C7S18_13100	ENOG4105C8N	cysteinyl-tRNA synthetase
C7S18_13110	ENOG4105DP0	ferredoxin-NADP reductase
C7S18_13120	ENOG41090A4	Pterin carbinolamine dehydratase
C7S18_13125	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C7S18_13130	ENOG4105D1H	recombination factor protein RarA
C7S18_13135	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7S18_13140	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C7S18_13145	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
C7S18_13155	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C7S18_13160	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C7S18_13165	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C7S18_13170	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C7S18_13175	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
C7S18_13225	ENOG4105CH5	extracellular solute-binding protein, family 7
C7S18_13250	ENOG4108EHX	EamA-like transporter family
C7S18_13255	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C7S18_13260	ENOG4105D0M	Protease HtpX homolog
C7S18_13265	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C7S18_13270	ENOG4105CHR	reductase
C7S18_13285	ENOG4105CHR	reductase
C7S18_13315	ENOG4105BZU	Histidine kinase
C7S18_13320	ENOG4105C7N	Xanthine uracil vitamin C permease
C7S18_13340	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C7S18_13345	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C7S18_13350	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C7S18_13355	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C7S18_13360	ENOG41082NX	50s ribosomal protein l35
C7S18_13365	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C7S18_13370	ENOG4105C22	threonyL-tRNA synthetase
C7S18_13405	ENOG4105CDV	Ompa motb domain protein
C7S18_13410	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
C7S18_13430	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C7S18_13435	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C7S18_13440	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C7S18_13445	ENOG4105DFF	Rod shape-determining protein mreb
C7S18_13450	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C7S18_13460	ENOG4105CJN	penicillin-binding protein
C7S18_13465	ENOG4105CNI	cell division protein FtsW
C7S18_13470	ENOG41085PJ	rdd domain containing protein
C7S18_13490	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
C7S18_13510	ENOG4105E96	Colicin v production protein
C7S18_13515	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C7S18_13520	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C7S18_13525	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C7S18_13535	ENOG4105CJP	fad dependent oxidoreductase
C7S18_13540	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C7S18_13545	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C7S18_13555	ENOG4105CJ1	ABC, transporter
C7S18_13570	ENOG4105D05	Receptor
C7S18_13580	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C7S18_13595	ENOG4105F64	nitrite reductase
C7S18_13605	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C7S18_13615	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C7S18_13625	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C7S18_13630	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C7S18_13645	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C7S18_13655	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
C7S18_13660	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
C7S18_13665	ENOG4105VMH	Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria (By similarity)
C7S18_13675	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C7S18_13680	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C7S18_13700	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C7S18_13705	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C7S18_13720	ENOG4105D9P	serine threonine protein kinase
C7S18_13725	ENOG4107XR4	alpha beta
C7S18_13730	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C7S18_13735	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
C7S18_13740	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_13775	ENOG4105KB2	stringent starvation protein b
C7S18_13780	ENOG4107MKT	Stringent starvation protein a
C7S18_13785	ENOG4105EIX	cytochrome c1
C7S18_13790	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C7S18_13795	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C7S18_13800	ENOG4105C0H	protease
C7S18_13805	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C7S18_13815	ENOG4105E66	phosphoriboisomerase A
C7S18_13820	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C7S18_13825	ENOG4105K46	50S ribosomal protein l27
C7S18_13830	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7S18_13835	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C7S18_13840	ENOG4105CJR	Integral membrane protein (MviN
C7S18_13860	ENOG4105CI2	imidazolone-5-propionate hydrolase
C7S18_13870	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C7S18_13875	ENOG4105CBS	Chea signal transduction histidine kinase
C7S18_13880	ENOG4105BZU	Histidine kinase
C7S18_13885	ENOG4105C8Q	Methyl-accepting chemotaxis
C7S18_13890	ENOG4108ZGA	chew protein
C7S18_13895	ENOG4108UNF	response regulator
C7S18_13900	ENOG4105D7Z	glutathione synthase
C7S18_13975	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
C7S18_14015	ENOG4105F0N	pyrophosphate phospho-hydrolase
C7S18_14020	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C7S18_14025	ENOG4105DKP	glycosyl transferase, family 9
C7S18_14060	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C7S18_14065	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C7S18_14070	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C7S18_14090	ENOG4108M15	ABC transporter
C7S18_14110	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C7S18_14120	ENOG4105ETE	Transcriptional regulator (LacI family
C7S18_14135	ENOG4107RUZ	Sss sodium solute transporter superfamily
C7S18_14140	ENOG4105CG3	alpha amylase, catalytic region
C7S18_14145	ENOG4105C4W	S-formylglutathione hydrolase
C7S18_14180	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C7S18_14190	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C7S18_14195	ENOG4105ETE	Transcriptional regulator (LacI family
C7S18_14200	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
C7S18_14205	ENOG4105CHR	reductase
C7S18_14210	ENOG4105W3S	hemerythrin-like, metal-binding protein
C7S18_14225	ENOG4105CAY	ferredoxin--nadp reductase
C7S18_14250	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C7S18_14260	ENOG4105CTB	Polyprenyl synthetase
C7S18_14270	ENOG4105D9P	serine threonine protein kinase
C7S18_14285	ENOG4105DEU	major facilitator superfamily
C7S18_14290	ENOG41062A4	Transcriptional regulator
C7S18_14300	ENOG4105F1J	Homogentisate 1,2-dioxygenase
C7S18_14315	ENOG4108RXX	maleylacetoacetate isomerase
C7S18_14330	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C7S18_14350	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
C7S18_14360	ENOG4107QN2	dihydrolipoyl dehydrogenase
C7S18_14365	ENOG4107QSN	dihydrolipoamide acetyltransferase
C7S18_14375	ENOG4105D9P	serine threonine protein kinase
C7S18_14380	ENOG4106NZI	LysR family Transcriptional regulator
C7S18_14385	ENOG4105DQ4	alcohol dehydrogenase
C7S18_14395	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C7S18_14405	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C7S18_14420	ENOG4108NEV	two component transcriptional regulator, LytTR family
C7S18_14425	ENOG4108KHS	signal transduction Histidine kinase
C7S18_14435	ENOG4105BZS	acriflavin resistance protein
C7S18_14450	ENOG4108DT4	serine threonine protein kinase
C7S18_14460	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C7S18_14470	ENOG4105C1J	atp-dependent rna helicase
C7S18_14485	ENOG4108XC3	NADH ubiquinone oxidoreductase
C7S18_14490	ENOG4105K64	Glycosyl transferase, family 2
C7S18_14500	ENOG4105C0H	protease
C7S18_14505	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7S18_14510	ENOG4105BZU	Histidine kinase
C7S18_14525	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7S18_14535	ENOG4105D9P	serine threonine protein kinase
C7S18_14545	ENOG4107R1Y	fructose-bisphosphate aldolase
C7S18_14560	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C7S18_14565	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C7S18_14580	ENOG4107ENK	receptor
C7S18_14655	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C7S18_14685	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C7S18_14705	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C7S18_14750	ENOG4105CJ1	ABC, transporter
C7S18_14760	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C7S18_14780	ENOG4105D9P	serine threonine protein kinase
C7S18_14790	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C7S18_14800	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C7S18_14805	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C7S18_14830	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7S18_14840	ENOG41069P5	Protein slyX homolog
C7S18_14855	ENOG4108QV3	biosynthesis protein
C7S18_14880	ENOG4105DJ4	phosphatidylserine decarboxylase
C7S18_14890	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C7S18_14895	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C7S18_14900	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C7S18_14915	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C7S18_14945	ENOG4105HBR	Rna-binding protein
C7S18_14950	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
C7S18_14955	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C7S18_14965	ENOG4105D9P	serine threonine protein kinase
C7S18_14975	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
C7S18_14990	ENOG4105D9P	serine threonine protein kinase
C7S18_15010	ENOG4105D9P	serine threonine protein kinase
C7S18_15030	ENOG4108IG5	Transcriptional regulator
C7S18_15040	ENOG4107QPN	acyl-Coa dehydrogenase
C7S18_15050	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C7S18_15065	ENOG4105QVC	MOSC domain-containing protein
C7S18_15095	ENOG4108JA2	transcriptioN-repair coupling factor
C7S18_15100	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C7S18_15110	ENOG4105EEI	dihydropteroate synthase
C7S18_15115	ENOG41072GX	Peptidase M22 Glycoprotease
C7S18_15120	ENOG4105CT7	inner membrane cred family protein
C7S18_15145	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
C7S18_15150	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C7S18_15160	ENOG4105DUX	Transporter
C7S18_15195	ENOG4105CD3	dihydroorotase
C7S18_15230	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
C7S18_15240	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C7S18_15265	ENOG4108Z33	Thiol disulfide Interchange Protein
C7S18_15270	ENOG4106RE7	Cytochrome
C7S18_15275	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C7S18_15285	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C7S18_15290	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C7S18_15295	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C7S18_15300	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C7S18_15330	ENOG4105D9P	serine threonine protein kinase
C7S18_15350	ENOG4105ECQ	AraC Family Transcriptional Regulator
C7S18_15355	ENOG4106KE4	Dehydrogenase
C7S18_15385	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C7S18_15390	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C7S18_15405	ENOG4107E2E	PKHD-type hydroxylase
C7S18_15410	ENOG4107E2E	PKHD-type hydroxylase
C7S18_15455	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
C7S18_15485	ENOG4105BZU	Histidine kinase
C7S18_15500	ENOG4105VEJ	Heat shock protein
C7S18_15525	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C7S18_15540	ENOG4105C25	Primosomal protein n'
C7S18_15545	ENOG4105BZU	Histidine kinase
C7S18_15550	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C7S18_15560	ENOG4108R99	pseudouridine synthase
C7S18_15575	ENOG4107YHX	fad dependent oxidoreductase
C7S18_15600	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_15625	ENOG4107RE3	peptidase, S41
C7S18_15665	ENOG4105D9P	serine threonine protein kinase
C7S18_15690	ENOG4105D9P	serine threonine protein kinase
C7S18_15730	ENOG41068W2	Cytochrome p-450
C7S18_15755	ENOG4108DT4	serine threonine protein kinase
C7S18_15785	ENOG4105FQP	Beta-lactamase
C7S18_15800	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_15890	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
C7S18_15895	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
C7S18_15900	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C7S18_15905	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
C7S18_15915	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C7S18_15925	ENOG4105C8P	)-transporter
C7S18_15955	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
C7S18_15960	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C7S18_15965	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C7S18_15970	ENOG41080ZE	Adenylate cyclase
C7S18_15975	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C7S18_15980	ENOG4105CNA	YD repeat protein
C7S18_16000	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
C7S18_16005	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C7S18_16010	ENOG4108ZT0	50S ribosomal protein l17
C7S18_16015	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C7S18_16020	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C7S18_16025	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C7S18_16030	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7S18_16035	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C7S18_16040	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C7S18_16045	ENOG41087MT	50S ribosomal protein L30
C7S18_16050	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C7S18_16055	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C7S18_16065	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C7S18_16070	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C7S18_16075	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7S18_16080	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C7S18_16085	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C7S18_16090	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C7S18_16095	ENOG41083MP	50s ribosomal protein l29
C7S18_16100	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C7S18_16105	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C7S18_16110	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C7S18_16115	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C7S18_16120	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7S18_16125	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C7S18_16130	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C7S18_16135	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C7S18_16140	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C7S18_16145	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C7S18_16150	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C7S18_16160	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C7S18_16165	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C7S18_16170	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C7S18_16175	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C7S18_16180	ENOG4108VZM	50s ribosomal protein L10
C7S18_16185	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C7S18_16190	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C7S18_16200	ENOG4105PM1	preprotein translocase subunit SecE
C7S18_16210	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C7S18_16270	ENOG41083WA	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
C7S18_16290	ENOG4105DTN	riboflavin biosynthesis protein ribF
C7S18_16295	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C7S18_16300	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C7S18_16305	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C7S18_16325	ENOG4105CI1	PTS System
C7S18_16330	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C7S18_16335	ENOG4105E2D	ec 3.2.1.52
C7S18_16345	ENOG4105FDP	GntR family transcriptional regulator
C7S18_16350	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C7S18_16355	ENOG4105CE4	GlcNAc 6-P deacetylase
C7S18_16385	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C7S18_16390	ENOG4105CE9	30S ribosomal protein S2
C7S18_16425	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C7S18_16430	ENOG4105ES4	Nitrilase
C7S18_16435	ENOG4105DR5	peptidase
C7S18_16440	ENOG4105CZX	twitching motility protein
C7S18_16450	ENOG4105CSR	polyphosphate kinase 2
C7S18_16455	ENOG4105NVB	glycoside hydrolase, family 19
C7S18_16465	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C7S18_16475	ENOG4105CBS	Chea signal transduction histidine kinase
C7S18_16490	ENOG4105M3Z	response regulator
C7S18_16495	ENOG4108KXV	response regulator
C7S18_16500	ENOG4105C8V	SAICAR synthetase
C7S18_16505	ENOG4105CPN	adenine deaminase
C7S18_16505	ENOG4105CPN	adenine deaminase
C7S18_16510	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
C7S18_16525	ENOG4105C7I	Dehydrogenase
C7S18_16535	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C7S18_16540	ENOG4105DU1	integral membrane protein, terc
C7S18_16555	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C7S18_16560	ENOG4105CD8	aminopeptidase N
C7S18_16590	ENOG4105D9P	serine threonine protein kinase
C7S18_16595	ENOG4105D9M	gamma-glutamylcysteine synthetase
C7S18_16600	ENOG4107RRY	Cyanophycin synthetase
C7S18_16615	ENOG4105E4G	Type IV pilus
C7S18_16640	ENOG4108JQC	penicillin-binding protein 1A
C7S18_16650	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
C7S18_16660	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C7S18_16670	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C7S18_16675	ENOG4105C9X	ppx gppa phosphatase
C7S18_16690	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C7S18_16700	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C7S18_16710	ENOG4105DGW	oligopeptidase A
C7S18_16720	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C7S18_16745	ENOG4108JHT	EamA-like transporter family
C7S18_16790	ENOG4105DWY	Agmatine deiminase
C7S18_16870	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C7S18_16875	ENOG4105C5Q	Transcriptional regulator
C7S18_16895	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C7S18_16905	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C7S18_16920	ENOG4105K70	DNA-binding protein
C7S18_16930	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C7S18_16935	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C7S18_16940	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C7S18_16985	ENOG4105CEY	Amp-dependent synthetase and ligase
C7S18_16990	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_17000	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_17040	ENOG4105C5F	glutamine synthetase
C7S18_17075	ENOG4108J2P	Alpha beta hydrolase fold
C7S18_17080	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_17095	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_17105	ENOG4105W0Z	cytoplasmic protein
C7S18_17110	ENOG4105C0P	Mg chelatase subunit ChlI
C7S18_17135	ENOG4105C4R	Atp-dependent dna helicase
C7S18_17140	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
C7S18_17145	ENOG4105BZU	Histidine kinase
C7S18_17150	ENOG4105D9P	serine threonine protein kinase
C7S18_17155	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7S18_17160	ENOG4105C34	Pseudouridine synthase
C7S18_17165	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C7S18_17170	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C7S18_17175	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C7S18_17190	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C7S18_17205	ENOG4108DT4	serine threonine protein kinase
C7S18_17215	ENOG4107QHF	type ii secretion system protein e
C7S18_17220	ENOG4105C1G	acyl-Coa dehydrogenase
C7S18_17260	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C7S18_17265	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C7S18_17290	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C7S18_17320	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
C7S18_17335	ENOG4105CX6	glutaminyL-tRNA synthetase
C7S18_17360	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_17365	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_17370	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_17380	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_17390	ENOG4107TXC	Transcriptional regulator
C7S18_17395	ENOG4105ETE	Transcriptional regulator (LacI family
C7S18_17400	ENOG4105CT4	transporter
C7S18_17405	ENOG4105CS2	ec 3.2.1.21
C7S18_17410	ENOG4107ZSV	Receptor
C7S18_17430	ENOG4105CBG	Sulfatase
C7S18_17440	ENOG4105BZA	Phosphoglycerate kinase
C7S18_17445	ENOG4105CA9	Pyruvate kinase
C7S18_17470	ENOG4105D9P	serine threonine protein kinase
C7S18_17480	ENOG4105P8Q	Curli production assembly transport component CsgG
C7S18_17490	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C7S18_17495	ENOG4105BZU	Histidine kinase
C7S18_17500	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C7S18_17505	ENOG4105BZU	Histidine kinase
C7S18_17510	ENOG4105BZU	Histidine kinase
C7S18_17525	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C7S18_17550	ENOG4105CSU	acyl-Coa dehydrogenase
C7S18_17565	ENOG4105E55	glycerol-3-phosphate acyltransferase
C7S18_17600	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C7S18_17615	ENOG4105CN1	protease
C7S18_17625	ENOG4107VAM	peptidase, m28
C7S18_17630	ENOG4105EEF	Alkane 1-monooxygenase
C7S18_17635	ENOG4108ZX5	transcriptional regulator
C7S18_17645	ENOG4105D9P	serine threonine protein kinase
C7S18_17675	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C7S18_17710	ENOG4105F2I	Transposase
C7S18_17845	ENOG4105E2T	synthase III
C7S18_17850	ENOG4105M2J	Glutaredoxin
C7S18_17860	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
C7S18_17880	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C7S18_17910	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
C7S18_17925	ENOG4105BZU	Histidine kinase
C7S18_17940	ENOG4105CY2	Citrate transporter
C7S18_17950	ENOG4108UW8	fha domain-containing protein
C7S18_17975	ENOG4105BZU	Histidine kinase
C7S18_17985	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C7S18_17990	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
C7S18_17995	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
C7S18_18000	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
C7S18_18005	ENOG4107YU2	histidine triad (hIT) protein
C7S18_18010	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C7S18_18015	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C7S18_18020	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C7S18_18055	ENOG4105DA5	(ABC) transporter
C7S18_18060	ENOG4105E3A	(ABC) transporter
C7S18_18070	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
C7S18_18080	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C7S18_18090	ENOG4105EY8	ABC transporter
C7S18_18115	ENOG4105BZU	Histidine kinase
C7S18_18125	ENOG4108VKM	cytochrome b561
C7S18_18140	ENOG4108S0S	Nucleotidyl transferase
C7S18_18160	ENOG4105F8V	Hydrolase, tatD family
C7S18_18170	ENOG4105CN1	protease
C7S18_18180	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C7S18_18185	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C7S18_18190	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C7S18_18215	ENOG4105BZU	Histidine kinase
C7S18_18220	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_18230	ENOG4105CJ1	ABC, transporter
C7S18_18250	ENOG4105E0X	reductase
C7S18_18255	ENOG4105C29	acyl-CoA thioesterase
C7S18_18265	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
C7S18_18270	ENOG4105BZU	Histidine kinase
C7S18_18275	ENOG4105BZU	Histidine kinase
C7S18_18280	ENOG4108UT2	hemolysin iii
C7S18_18310	ENOG4105D9P	serine threonine protein kinase
C7S18_18330	ENOG4105D0M	Protease HtpX homolog
C7S18_18335	ENOG4108V0P	LemA family
C7S18_18345	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C7S18_18360	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C7S18_18380	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
C7S18_18390	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C7S18_18395	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C7S18_18400	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C7S18_18405	ENOG4105VG0	50S ribosomal protein l34
C7S18_18420	ENOG4105EB3	Histidine kinase
C7S18_18425	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C7S18_18440	ENOG4105ED9	Protein of unknown function (DUF455)
C7S18_18445	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C7S18_18450	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C7S18_18465	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C7S18_18475	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C7S18_18515	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
C7S18_18520	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
C7S18_18525	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
C7S18_18530	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C7S18_18545	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
C7S18_18560	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C7S18_18565	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C7S18_18570	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C7S18_18580	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C7S18_18590	ENOG4105D9P	serine threonine protein kinase
C7S18_18615	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C7S18_18635	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C7S18_18640	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C7S18_18645	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C7S18_18675	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C7S18_18680	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C7S18_18700	ENOG4106I3Z	
C7S18_18710	ENOG4107QHF	type ii secretion system protein e
C7S18_18730	ENOG4105BZU	Histidine kinase
C7S18_18735	ENOG4105CJB	Exodeoxyribonuclease I
C7S18_18740	ENOG4105D9P	serine threonine protein kinase
C7S18_18745	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C7S18_18785	ENOG4108Z12	YiaAB two helix domain-containing protein
C7S18_18795	ENOG4105C4R	Atp-dependent dna helicase
C7S18_18895	ENOG4107RNH	Outer membrane receptor FepA
C7S18_18910	ENOG4105EQR	Transposase IS116 IS110 IS902
C7S18_18945	ENOG4105GRZ	Ycii-related protein
C7S18_18970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C7S18_18975	ENOG4107TUY	Histidine kinase
C7S18_18980	ENOG4105FYV	Amp nucleosidase
C7S18_18985	ENOG4105BZU	Histidine kinase
C7S18_18990	ENOG4105D05	Receptor
C7S18_19000	ENOG4105CHM	Aminotransferase
C7S18_19005	ENOG4105Y49	secretion protein, HlyD family
C7S18_19020	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C7S18_19025	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C7S18_19035	ENOG4105D4Y	metalloprotease
C7S18_19040	ENOG4105XDF	Protein of unknown function (DUF1272)
C7S18_19045	ENOG4107QMS	site-determining protein
C7S18_19050	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
C7S18_19065	ENOG4105C39	capsular polysaccharide phosphotransferase
C7S18_19075	ENOG4105CE1	Ferrous iron transport protein b
C7S18_19130	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C7S18_19300	ENOG4105CQ7	ATP-dependent helicase
C7S18_19310	ENOG4105DWV	Homoserine O-trans-acetylase
C7S18_19320	ENOG4105C9B	Cysteine desulfurase
C7S18_19325	ENOG4105JRK	feS assembly protein SufD
C7S18_19330	ENOG4105C3K	feS assembly ATPase SufC
C7S18_19345	ENOG4105KPV	Transcriptional regulator
C7S18_19360	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C7S18_19365	ENOG4107R11	Transcriptional regulator
C7S18_19370	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C7S18_19405	ENOG4105ERG	peptidase m48, ste24p
C7S18_19440	ENOG4105E0F	Histidine kinase
C7S18_19445	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C7S18_19460	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C7S18_19475	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C7S18_19560	ENOG4105D9P	serine threonine protein kinase
C7S18_19580	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C7S18_19640	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C7S18_19645	ENOG4108WUH	Transcriptional regulator, TetR family
C7S18_19675	ENOG4108WHA	ompa motb domain protein
C7S18_19825	ENOG4108NEV	two component transcriptional regulator, LytTR family
C7S18_19830	ENOG4108HRK	Histidine kinase
C7S18_19955	ENOG4105F2I	Transposase
C7S18_19960	ENOG410680H	amp-dependent synthetase and ligase
C7S18_19965	ENOG4105F2I	Transposase
C7S18_19980	ENOG410680H	amp-dependent synthetase and ligase
C7S18_19985	ENOG4105EUJ	GTP cyclohydrolase i
C7S18_19990	ENOG4105BZ1	(ABC) transporter
C7S18_19995	ENOG4108XG2	Histidine kinase
C7S18_20020	ENOG4107RDJ	Sulfotransferase
C7S18_20030	ENOG4107QHF	type ii secretion system protein e
C7S18_20065	ENOG4105C3F	Signal peptidase i
C7S18_20090	ENOG4105ETT	transcriptional Regulator, LysR family
C7S18_20110	ENOG4105DSY	exodeoxyribonuclease V, gamma
C7S18_20115	ENOG4105ES5	Histidine kinase
C7S18_20125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C7S18_20130	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C7S18_20140	ENOG4105CHU	acetyl-coa acetyltransferase
C7S18_20155	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
C7S18_20170	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C7S18_20220	ENOG4105CGK	Exodeoxyribonuclease III
C7S18_20285	ENOG4107QHF	type ii secretion system protein e
C7S18_20310	ENOG4107QHF	type ii secretion system protein e
C7S18_20355	ENOG4105K5B	UPF0225 protein
C7S18_20360	ENOG4105D9P	serine threonine protein kinase
C7S18_20375	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C7S18_20380	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C7S18_20385	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C7S18_20390	ENOG4105BZU	Histidine kinase
C7S18_20395	ENOG4108VB1	regulatoR
C7S18_20400	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C7S18_20405	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C7S18_20410	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C7S18_20425	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
C7S18_20430	ENOG4105BZU	Histidine kinase
C7S18_20445	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C7S18_20465	ENOG4105W5Q	DNA repair protein (RadC
C7S18_20475	ENOG4105BZS	acriflavin resistance protein
C7S18_20505	ENOG4105D9P	serine threonine protein kinase
C7S18_20520	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C7S18_20525	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C7S18_20540	ENOG4105E3A	(ABC) transporter
C7S18_20545	ENOG4105DA5	(ABC) transporter
C7S18_20550	ENOG41085PJ	rdd domain containing protein
C7S18_20555	ENOG4108RPN	Protein smg homolog
C7S18_20560	ENOG4105C79	DNA protecting protein DprA
C7S18_20575	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C7S18_20580	ENOG4107QZM	n-acetylglutamate synthase
C7S18_20585	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C7S18_20610	ENOG4105CK7	Sodium proline symporter
C7S18_20625	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C7S18_20635	ENOG4108M7F	enoyl-CoA hydratase isomerase
C7S18_20645	ENOG4106IPI	cyclase, family
C7S18_20680	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_20695	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C7S18_20700	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C7S18_20705	ENOG4105C28	cystathionine
C7S18_20715	ENOG4105MIR	Phenylalanine 4-monooxygenase
C7S18_20745	ENOG4105KD7	acetyltransferase
C7S18_20750	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C7S18_20755	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C7S18_20760	ENOG4105CDY	transcriptional regulatory protein
C7S18_20770	ENOG4105CJ1	ABC, transporter
C7S18_20780	ENOG4105JJR	Histidine kinase
C7S18_20790	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C7S18_20855	ENOG4107QHF	type ii secretion system protein e
C7S18_20890	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
C7S18_20895	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C7S18_20915	ENOG4108XG2	Histidine kinase
C7S18_20925	ENOG4108VB1	regulatoR
C7S18_20955	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7S18_20980	ENOG4108K3A	Glutathione S-transferase
C7S18_21005	ENOG4105DUM	transcriptional regulator, lysR family
C7S18_21010	ENOG4107S78	Band 7 protein
C7S18_21030	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C7S18_21040	ENOG4105BZU	Histidine kinase
C7S18_21065	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7S18_21070	ENOG4107ZVW	dihydroneopterin aldolase
C7S18_21075	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C7S18_21085	ENOG4107R6D	beta-lactam binding protein AmpH
C7S18_21095	ENOG4108VAC	response regulator
C7S18_21100	ENOG4105BZM	domain protein
C7S18_21105	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
C7S18_21115	ENOG4105F95	Monooxygenase
C7S18_21130	ENOG4105CD3	dihydroorotase
C7S18_21135	ENOG4105CD3	dihydroorotase
C7S18_21160	ENOG4105F2I	Transposase
C7S18_21200	ENOG4105ECQ	AraC Family Transcriptional Regulator
C7S18_21225	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C7S18_21230	ENOG4105DSJ	YicC domain protein
C7S18_21240	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C7S18_21250	ENOG4105CSR	polyphosphate kinase 2
C7S18_21255	ENOG4108V5V	Serine Threonine protein kinase
C7S18_21265	ENOG4105CDV	Ompa motb domain protein
C7S18_21325	ENOG4105F2I	Transposase
C7S18_21335	ENOG4107VAM	peptidase, m28
C7S18_21340	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C7S18_21345	ENOG4107R34	abc transporter permease protein
C7S18_21365	ENOG4108EX3	reductase
C7S18_21370	ENOG4105C0D	helicase
C7S18_21385	ENOG4105CH2	amidohydrolase
C7S18_21390	ENOG4107QHF	type ii secretion system protein e
C7S18_21415	ENOG4105D78	K07001 NTE family protein
C7S18_21420	ENOG4105BZU	Histidine kinase
C7S18_21425	ENOG4105WH1	Two component transcriptional regulator luxr family
C7S18_21430	ENOG4105C9K	Endothelin-converting enzyme 1
C7S18_21460	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C7S18_21495	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C7S18_21500	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C7S18_21505	ENOG4105CTU	Proline racemase
C7S18_21515	ENOG4108WYP	Transcriptional regulator
C7S18_21540	ENOG4105C9M	aspartyl-trna synthetase
C7S18_21545	ENOG4107RGH	Aldehyde dehydrogenase
C7S18_21565	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C7S18_21570	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C7S18_21600	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
C7S18_21605	ENOG4105CPC	Aldo Keto reductase
C7S18_21610	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
C7S18_21615	ENOG4106TYC	homoserine o-acetyltransferase (EC 2.3.1.31)
C7S18_21620	ENOG4105C28	cystathionine
C7S18_21630	ENOG4105D6Z	AFG1 family ATPase
C7S18_21640	ENOG4105D64	Mechanosensitive ion channel
C7S18_21655	ENOG4105VCQ	rubredoxin
C7S18_21670	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C7S18_21675	ENOG4105E09	nadh pyrophosphatase
C7S18_21685	ENOG4108UJU	UPF0301 protein
C7S18_21690	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C7S18_21695	ENOG4108I5C	dEAD DEAH box helicase
C7S18_21710	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_21715	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_21720	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C7S18_21745	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C7S18_21750	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
C7S18_21755	ENOG4105C02	permease
C7S18_21760	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C7S18_21775	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C7S18_21785	ENOG4105CEY	Amp-dependent synthetase and ligase
C7S18_21790	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C7S18_21805	ENOG4105CQB	FAD linked oxidase domain protein
C7S18_21820	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C7S18_21825	ENOG4105DP4	dak2 domain fusion protein ylov
C7S18_21865	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C7S18_21905	ENOG4105EMN	RNA polymerase sigma factor
C7S18_21925	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C7S18_21930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C7S18_21940	ENOG4105CAK	Cell division ATP-binding protein ftsE
C7S18_21945	ENOG4105D7Q	type ii secretion system
C7S18_21955	ENOG4105CXT	aspartate transcarbamylase
C7S18_21960	ENOG4105CDV	Ompa motb domain protein
C7S18_21965	ENOG4105VG1	fes assembly suf system protein
C7S18_21980	ENOG4105KTH	gatB Yqey
C7S18_22000	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
C7S18_22005	ENOG4105N42	UPF0307 protein
C7S18_22040	ENOG41063SB	peptidase
C7S18_22045	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C7S18_22050	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
C7S18_22060	ENOG4107QHF	type ii secretion system protein e
C7S18_22065	ENOG4105D7Q	type ii secretion system
C7S18_22070	ENOG4108VAU	general secretion pathway protein G
C7S18_22075	ENOG4105WMT	general secretion pathway protein h
C7S18_22080	ENOG41069G9	General secretion pathway protein J
C7S18_22085	ENOG4105UV2	general secretion pathway protein K
C7S18_22090	ENOG41090VX	general secretion pathway protein L
C7S18_22105	ENOG4105GVR	general secretion pathway protein D
C7S18_22125	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
C7S18_22160	ENOG4105C12	Phosphoribosylglycinamide synthetase
C7S18_22165	ENOG4107104	thymidine kinase
C7S18_22180	ENOG4108TEB	UPF0114 protein
C7S18_22190	ENOG4105CJ1	ABC, transporter
C7S18_22205	ENOG4105BZU	Histidine kinase
C7S18_22235	ENOG4105CYM	Glutathione S-transferase
C7S18_22255	ENOG4105KRS	Proteinase inhibitor
C7S18_22260	ENOG4105E2X	shikimate dehydrogenase
C7S18_22265	ENOG4105C2M	dna polymerase I
C7S18_22285	ENOG4105DH7	May be involved in recombination (By similarity)
C7S18_22290	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C7S18_22295	ENOG4105BZU	Histidine kinase
C7S18_22300	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C7S18_22310	ENOG4105CJ1	ABC, transporter
C7S18_22315	ENOG4107QWP	ABC-2 type transporter
C7S18_22340	ENOG4107QPV	Serine Threonine protein kinase
C7S18_22350	ENOG4107SVH	Potassium channel protein
C7S18_22385	ENOG4105EMN	RNA polymerase sigma factor
C7S18_22415	ENOG4105C5S	asparaginyl-tRNA synthetase
C7S18_22420	ENOG4108Z4V	iron-sulfur cluster assembly
C7S18_22425	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C7S18_22430	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C7S18_22440	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
C7S18_22450	ENOG4107RAN	Peptidase, M16
C7S18_22495	ENOG4108YZN	class I peptide chain release factor
C7S18_22505	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C7S18_22520	ENOG4105T95	Thiol disulfide interChange protein
C7S18_22525	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C7S18_22550	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C7S18_22560	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C7S18_22585	ENOG4107QKA	exodeoxyribonuclease V beta
C7S18_22590	ENOG4105C7H	Helicase, RecD TraA family
C7S18_22595	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
C7S18_22615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C7S18_22645	ENOG4105CI2	imidazolone-5-propionate hydrolase
C7S18_22650	ENOG4105EHM	Aminoglycoside phosphotransferase
C7S18_22655	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
C7S18_22665	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
C7S18_22670	ENOG4107YD3	Thioesterase
C7S18_22675	ENOG4105E02	MotA TolQ exbB proton channel
C7S18_22680	ENOG4105M8F	Biopolymer transport protein exbD tolR
C7S18_22690	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C7S18_22695	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C7S18_22705	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C7S18_22720	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C7S18_22740	ENOG4106855	Competence protein
C7S18_22770	ENOG4108R85	Short chain dehydrogenase
C7S18_22775	ENOG4105DR4	Methyltransferase
C7S18_22780	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C7S18_22895	ENOG4105E7W	lamb ycsf family protein
C7S18_22905	ENOG4105P4J	Allophanate hydrolase, subunit 1
C7S18_22920	ENOG4105C2C	drug resistance transporter, Bcr CflA
C7S18_22935	ENOG4105CVA	phosphate
C7S18_22985	ENOG4105CB5	ATP-dependent DNA helicase recG
C7S18_22990	ENOG4105KME	endoribonuclease L-psp
C7S18_22995	ENOG4108KPZ	tonB-dependent Receptor
C7S18_23000	ENOG4108DG9	Smr protein MutS2
C7S18_23020	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
C7S18_23030	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
C7S18_23040	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C7S18_23065	ENOG4108SHN	Glycosyl transferase, family 2
C7S18_23090	ENOG4105EY8	ABC transporter
C7S18_23100	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
C7S18_23120	ENOG4107QQG	Dehydrogenase
C7S18_23160	ENOG41083UI	stage II sporulation protein
C7S18_23170	ENOG4105IJJ	transcriptional regulator, crp fnr family
C7S18_23190	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
C7S18_23195	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C7S18_23200	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C7S18_23205	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C7S18_23215	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C7S18_23220	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C7S18_23225	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C7S18_23250	ENOG4105C5H	ABC transporter
C7S18_23260	ENOG4105C5H	ABC transporter
C7S18_23265	ENOG4108IJ6	ABC transporter
C7S18_23275	ENOG4108I5D	sulfate abc transporter
C7S18_23280	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
C7S18_23295	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
C7S18_23300	ENOG4105CPW	cytochrome b561
C7S18_23320	ENOG4108IJ6	ABC transporter
C7S18_23335	ENOG4107QK7	reductase
C7S18_23350	ENOG4105BZU	Histidine kinase
C7S18_23365	ENOG4105C4K	Nad synthetase
C7S18_23440	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
C7S18_23475	ENOG4105D7V	transposase
C7S18_23505	ENOG4105CB5	ATP-dependent DNA helicase recG
C7S18_23520	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C7S18_23570	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C7S18_23575	ENOG4107QHF	type ii secretion system protein e
C7S18_23600	ENOG4107QHF	type ii secretion system protein e
C7S18_23720	ENOG4105D7V	transposase
C7S18_23785	ENOG4105CDU	Replicative dna helicase
C7S18_23795	ENOG4105C4R	Atp-dependent dna helicase
C7S18_23965	ENOG4108UUM	single-stranded DNA-binding protein
C7S18_24025	ENOG4105C4R	Atp-dependent dna helicase
C7S18_24045	ENOG4105D85	methylase
C7S18_24070	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)