locus-tag	class	description
C1O57_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C1O57_00010	ENOG4105CJ1	ABC, transporter
C1O57_00030	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
C1O57_00050	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C1O57_00055	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
C1O57_00080	ENOG4105EPC	oxidoreductase
C1O57_00095	ENOG4108ISG	Major Facilitator
C1O57_00100	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C1O57_00115	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C1O57_00120	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
C1O57_00145	ENOG4108IAJ	Nad-dependent epimerase dehydratase
C1O57_00170	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C1O57_00220	ENOG4105E5D	amino acid
C1O57_00225	ENOG4105CSV	Glutaminase
C1O57_00240	ENOG4105BZG	amino acid carrier protein
C1O57_00250	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C1O57_00255	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C1O57_00260	ENOG4105C25	Primosomal protein n'
C1O57_00265	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C1O57_00290	ENOG4107QJQ	Mate efflux family protein
C1O57_00330	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C1O57_00335	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C1O57_00340	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
C1O57_00355	ENOG4105DIK	(ABC) transporter
C1O57_00365	ENOG4108Z0C	Uvrb UvrC protein
C1O57_00370	ENOG41066A3	ATP guanido phosphotransferase
C1O57_00375	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C1O57_00385	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C1O57_00390	ENOG4105ERH	Fumarylacetoacetate hydrolase
C1O57_00395	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C1O57_00410	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C1O57_00420	ENOG4105C31	Tryptophanyl-tRNA synthetase
C1O57_00430	ENOG4105D48	metallophosphoesterase
C1O57_00440	ENOG4105CUZ	uba thif-type nad fad binding protein
C1O57_00505	ENOG4105DZR	Type I site-specific deoxyribonuclease
C1O57_00510	ENOG4107XZC	Restriction modification system DNA (Specificity
C1O57_00520	ENOG4106H3A	restriction
C1O57_00590	ENOG4105D7K	pfkb domain protein
C1O57_00595	ENOG4105E09	nadh pyrophosphatase
C1O57_00610	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C1O57_00620	ENOG4107QJE	Chromosome Partitioning Protein
C1O57_00625	ENOG4105D9P	serine threonine protein kinase
C1O57_00665	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C1O57_00680	ENOG4105K78	MarR family Transcriptional regulator
C1O57_00690	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C1O57_00695	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C1O57_00705	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
C1O57_00710	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C1O57_00715	ENOG41083ND	50S ribosomal protein L33
C1O57_00720	ENOG4105SCY	DNAK suppressor
C1O57_00725	ENOG4105DKQ	ROK family
C1O57_00730	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C1O57_00740	ENOG4105M6F	mutator MutT protein
C1O57_00745	ENOG4105CW7	secretion protein, HlyD family
C1O57_00750	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1O57_00755	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1O57_00760	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C1O57_00775	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C1O57_00790	ENOG4108R96	Methyltransferase, YaeB family
C1O57_00795	ENOG4105CD3	dihydroorotase
C1O57_00800	ENOG4105CXT	aspartate transcarbamylase
C1O57_00805	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
C1O57_00820	ENOG4105DZ0	fad dependent oxidoreductase
C1O57_00825	ENOG4105DWY	Agmatine deiminase
C1O57_00835	ENOG4105DZP	Membrane-associated zinc metalloprotease
C1O57_00845	ENOG41061MV	Arylsulfatase
C1O57_00855	ENOG4105CE1	Ferrous iron transport protein b
C1O57_00880	ENOG4105DF5	DNA topoisomerase IV, subunit A
C1O57_00915	ENOG4105FA0	parb-like partition protein
C1O57_00945	ENOG4105DHU	Bile acid
C1O57_00970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C1O57_00975	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C1O57_00980	ENOG4107QSI	ABC, transporter
C1O57_01020	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C1O57_01035	ENOG4105BZ1	(ABC) transporter
C1O57_01040	ENOG4105BZ1	(ABC) transporter
C1O57_01060	ENOG4105DHJ	ABC, transporter
C1O57_01065	ENOG4107PE3	Mammalian cell entry related domain protein
C1O57_01085	ENOG4105CZX	twitching motility protein
C1O57_01090	ENOG4105CZX	twitching motility protein
C1O57_01095	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C1O57_01115	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C1O57_01120	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C1O57_01125	ENOG4107RJ1	sodium solute
C1O57_01155	ENOG4108JQC	penicillin-binding protein 1A
C1O57_01165	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C1O57_01170	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C1O57_01180	ENOG4105D60	lipoprotein releasing system transmembrane protein
C1O57_01180	ENOG4105D60	lipoprotein releasing system transmembrane protein
C1O57_01240	ENOG4107VAM	peptidase, m28
C1O57_01250	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C1O57_01255	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C1O57_01270	ENOG4105C9B	Cysteine desulfurase
C1O57_01280	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
C1O57_01290	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C1O57_01300	ENOG4108ZVT	methylmalonyl-coA epimerase
C1O57_01305	ENOG4107QX3	carboxylase
C1O57_01315	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
C1O57_01320	ENOG4105D9Q	decarboxylase (Beta subunit)
C1O57_01325	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C1O57_01330	ENOG4105CYC	Transferase
C1O57_01345	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
C1O57_01350	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
C1O57_01355	ENOG4105CTQ	phosphohexokinase
C1O57_01365	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C1O57_01370	ENOG4105C7K	acetolactate synthase
C1O57_01390	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
C1O57_01395	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C1O57_01405	ENOG4105C8P	)-transporter
C1O57_01485	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C1O57_01490	ENOG4105CPQ	Dehydrogenase
C1O57_01500	ENOG4105EYW	Ion transport protein
C1O57_01505	ENOG41080E8	Transcriptional regulator, Spx MgsR family
C1O57_01510	ENOG4105CY0	Metallo-Beta-Lactamase
C1O57_01520	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C1O57_01530	ENOG4105FE9	pseudouridine synthase
C1O57_01540	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C1O57_01545	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
C1O57_01555	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C1O57_01610	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C1O57_01615	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C1O57_01620	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C1O57_01625	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C1O57_01660	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1O57_01785	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C1O57_01790	ENOG4105E0X	reductase
C1O57_01795	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C1O57_01805	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C1O57_01820	ENOG4105C8J	)-transporter
C1O57_01825	ENOG4105D3R	alkyl hydroperoxide reductase
C1O57_01835	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C1O57_01840	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C1O57_01885	ENOG4105C1V	Peptidase, M16
C1O57_01900	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C1O57_01910	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C1O57_01925	ENOG4105E2Z	phosphate ABC transporter (Permease
C1O57_01930	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C1O57_01935	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
C1O57_01955	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C1O57_01960	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
C1O57_01980	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C1O57_02005	ENOG4105E6M	Sulphatase-modifying factor protein
C1O57_02010	ENOG4105CFP	Peptidase U32
C1O57_02020	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C1O57_02025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C1O57_02045	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C1O57_02050	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C1O57_02060	ENOG4105DIN	metallophosphoesterase
C1O57_02065	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C1O57_02115	ENOG4105C3M	thioredoxin reductase
C1O57_02120	ENOG4105EJQ	L-serine dehydratase
C1O57_02135	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C1O57_02145	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C1O57_02150	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C1O57_02155	ENOG4105DSB	aldose 1-epimerase
C1O57_02185	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C1O57_02190	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C1O57_02200	ENOG4105CBC	glutamate synthase
C1O57_02210	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C1O57_02215	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C1O57_02220	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
C1O57_02225	ENOG4105C30	Nad-dependent epimerase dehydratase
C1O57_02230	ENOG4105DFD	Na H antiporter
C1O57_02240	ENOG4105DG6	mannose-6-phosphate isomerase
C1O57_02250	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C1O57_02260	ENOG4108JQC	penicillin-binding protein 1A
C1O57_02270	ENOG4109015	Biopolymer transport protein exbD tolR
C1O57_02285	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C1O57_02290	ENOG4108UJD	30S ribosomal protein S9
C1O57_02295	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C1O57_02300	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C1O57_02305	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C1O57_02310	ENOG4105W5Q	DNA repair protein (RadC
C1O57_02330	ENOG4105C6E	dna polymerase iii
C1O57_02335	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C1O57_02355	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
C1O57_02410	ENOG4105D49	3-dehydroquinate synthase
C1O57_02430	ENOG4107SFQ	iron-sulfur binding
C1O57_02445	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
C1O57_02450	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
C1O57_02460	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C1O57_02465	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C1O57_02470	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C1O57_02475	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C1O57_02485	ENOG4105CAS	nag kinase
C1O57_02510	ENOG4108JJB	ABC transporter
C1O57_02515	ENOG4105DVT	helicase
C1O57_02525	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C1O57_02530	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
C1O57_02540	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
C1O57_02545	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C1O57_02555	ENOG41085AM	50S ribosomal protein L28
C1O57_02570	ENOG4105CJ2	(LipO)protein
C1O57_02575	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
C1O57_02580	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C1O57_02590	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C1O57_02605	ENOG4105C6F	GntR Family Transcriptional Regulator
C1O57_02610	ENOG4105DKW	ABC transporter
C1O57_02615	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C1O57_02630	ENOG4105ECP	epimerase
C1O57_02660	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1O57_02720	ENOG4105V75	Transcriptional regulator
C1O57_02735	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C1O57_02760	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C1O57_02765	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C1O57_02770	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C1O57_02820	ENOG4105CNA	YD repeat protein
C1O57_02900	ENOG4105D9P	serine threonine protein kinase
C1O57_02915	ENOG4105E4P	ATPase (AAA
C1O57_02930	ENOG4107QI1	Mate efflux family protein
C1O57_02950	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C1O57_02955	ENOG4105CMR	udp-glucose 4-epimerase
C1O57_02995	ENOG4105E0M	Sulfatase
C1O57_03065	ENOG4105C01	Dihydroxy-acid dehydratase
C1O57_03070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C1O57_03075	ENOG4105BZU	Histidine kinase
C1O57_03100	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C1O57_03105	ENOG4107RAQ	aminopeptidase
C1O57_03115	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C1O57_03145	ENOG4105GVR	general secretion pathway protein D
C1O57_03150	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C1O57_03155	ENOG4105C59	p-type ATPase
C1O57_03160	ENOG4105DKQ	ROK family
C1O57_03165	ENOG4108Z6B	deaminase
C1O57_03170	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C1O57_03175	ENOG4105CA0	peroxidase
C1O57_03190	ENOG4105CE1	Ferrous iron transport protein b
C1O57_03240	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C1O57_03245	ENOG4108IYU	L-aspartate oxidase
C1O57_03255	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
C1O57_03270	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C1O57_03275	ENOG4105CBG	Sulfatase
C1O57_03305	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
C1O57_03310	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C1O57_03315	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
C1O57_03360	ENOG4108IJF	Heavy metal efflux pump, CzcA
C1O57_03380	ENOG4105SYT	Methylenetetrahydrofolate reductase
C1O57_03390	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1O57_03400	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C1O57_03405	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C1O57_03415	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C1O57_03425	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C1O57_03440	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C1O57_03445	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C1O57_03450	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C1O57_03455	ENOG4107Z3D	50S ribosomal protein l10
C1O57_03460	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C1O57_03465	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C1O57_03470	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C1O57_03500	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C1O57_03510	ENOG4105CBG	Sulfatase
C1O57_03515	ENOG4105E2D	ec 3.2.1.52
C1O57_03535	ENOG4105C5H	ABC transporter
C1O57_03540	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C1O57_03570	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
C1O57_03575	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C1O57_03630	ENOG4105CPC	Aldo Keto reductase
C1O57_03640	ENOG4105ENX	hydrolase
C1O57_03650	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
C1O57_03670	ENOG4105MS2	ribosomal subunit Interface protein
C1O57_03680	ENOG4105C5H	ABC transporter
C1O57_03690	ENOG4105CHR	reductase
C1O57_03710	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C1O57_03715	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C1O57_03740	ENOG4105EN6	Membrane
C1O57_03745	ENOG4105CY0	Metallo-Beta-Lactamase
C1O57_03750	ENOG4108V6E	Cell division protein mraZ
C1O57_03755	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C1O57_03765	ENOG4105CJN	penicillin-binding protein
C1O57_03770	ENOG4105CJN	penicillin-binding protein
C1O57_03775	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C1O57_03780	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
C1O57_03785	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C1O57_03790	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C1O57_03800	ENOG4105CNI	cell division protein FtsW
C1O57_03805	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C1O57_03810	ENOG4105DFU	Cell wall formation (By similarity)
C1O57_03825	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C1O57_03830	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
C1O57_03835	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C1O57_03840	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C1O57_03845	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C1O57_03855	ENOG4105C0H	protease
C1O57_03865	ENOG4105D49	3-dehydroquinate synthase
C1O57_03870	ENOG4108JQ7	(ABC) transporter
C1O57_03875	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C1O57_03880	ENOG4105CE9	30S ribosomal protein S2
C1O57_03905	ENOG4108IUZ	ABC transporter
C1O57_03915	ENOG4105DFU	Cell wall formation (By similarity)
C1O57_03920	ENOG4105UYK	outer membrane protein a
C1O57_03950	ENOG4105C5S	asparaginyl-tRNA synthetase
C1O57_03960	ENOG4105K63	Thioredoxin
C1O57_04005	ENOG4105DUM	transcriptional regulator, lysR family
C1O57_04010	ENOG4105HMI	Membrane
C1O57_04020	ENOG4107STF	Involved in phosphonate degradation (By similarity)
C1O57_04045	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C1O57_04050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C1O57_04055	ENOG4105CDY	transcriptional regulatory protein
C1O57_04065	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C1O57_04075	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C1O57_04080	ENOG4105DI5	UPF0365 protein
C1O57_04090	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C1O57_04095	ENOG4107RY6	amino acid
C1O57_04110	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C1O57_04115	ENOG4107RCW	fructose-bisphosphate aldolase
C1O57_04120	ENOG4105CI3	gtp-binding protein typa
C1O57_04125	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C1O57_04155	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C1O57_04165	ENOG4105CPF	Cell wall formation (By similarity)
C1O57_04205	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C1O57_04210	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C1O57_04215	ENOG4105ESI	atpase involved in dna repair
C1O57_04225	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C1O57_04250	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C1O57_04255	ENOG4105X0D	Fimbrial protein
C1O57_04265	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
C1O57_04275	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C1O57_04285	ENOG4105DIN	metallophosphoesterase
C1O57_04305	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
C1O57_04310	ENOG4105K64	Glycosyl transferase, family 2
C1O57_04330	ENOG4105EXC	Acyl-transferase
C1O57_04390	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C1O57_04395	ENOG4105C5I	Dehydrogenase
C1O57_04405	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C1O57_04410	ENOG4105NAU	thioesterase Superfamily protein
C1O57_04420	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C1O57_04460	ENOG4105GTN	ParB Domain Protein Nuclease
C1O57_04465	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
C1O57_04480	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C1O57_04495	ENOG4105C0P	Mg chelatase subunit ChlI
C1O57_04530	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C1O57_04535	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C1O57_04545	ENOG4105CRK	lysyL-tRNA synthetase
C1O57_04550	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
C1O57_04560	ENOG4105KVH	Transcriptional regulator
C1O57_04570	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C1O57_04585	ENOG4105CQ7	ATP-dependent helicase
C1O57_04590	ENOG4108ZP8	Acetolactate synthase small subunit
C1O57_04595	ENOG4105C0H	protease
C1O57_04605	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C1O57_04610	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C1O57_04615	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C1O57_04625	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C1O57_04735	ENOG4105F8V	Hydrolase, tatD family
C1O57_04745	ENOG4105CNT	hydrolase family 2
C1O57_04760	ENOG4105C08	Histidine kinase
C1O57_04765	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
C1O57_04775	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C1O57_04780	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
C1O57_04785	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
C1O57_04800	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C1O57_04845	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C1O57_04855	ENOG4105CHH	sulfate transporter
C1O57_04860	ENOG4105CH7	arginosuccinase
C1O57_04875	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C1O57_04880	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
C1O57_04890	ENOG4105EQI	Metal Dependent Phosphohydrolase
C1O57_04900	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C1O57_04905	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C1O57_04925	ENOG41082EK	Restriction modification system DNA (Specificity
C1O57_04945	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C1O57_04950	ENOG4105DME	alpha-galactosidase
C1O57_04985	ENOG4105CMM	transposase
C1O57_04995	ENOG4105D0C	transport protein
C1O57_05010	ENOG4105C8P	)-transporter
C1O57_05050	ENOG4108RAC	Rubrerythrin
C1O57_05060	ENOG4105CN9	Peptidase m42 family protein
C1O57_05065	ENOG4105E2D	ec 3.2.1.52
C1O57_05075	ENOG4105G6Z	alkaline phosphatase
C1O57_05080	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
C1O57_05085	ENOG4105C8Y	Acetylornithine aminotransferase
C1O57_05105	ENOG4105C59	p-type ATPase
C1O57_05110	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C1O57_05115	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C1O57_05155	ENOG4105CPP	Dehydrogenase, E1 component
C1O57_05160	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C1O57_05165	ENOG4108Z6Z	Transcriptional regulator
C1O57_05170	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C1O57_05175	ENOG4105BZS	acriflavin resistance protein
C1O57_05215	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C1O57_05235	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
C1O57_05240	ENOG4107QM5	aconitate hydratase
C1O57_05265	ENOG4105E0Y	RtcB Protein
C1O57_05275	ENOG4105CZM	Major Facilitator
C1O57_05285	ENOG4108WBT	adenosyltransferase
C1O57_05295	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C1O57_05320	ENOG4105CFP	Peptidase U32
C1O57_05325	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C1O57_05340	ENOG410823G	oxidoreductase
C1O57_05345	ENOG4105C0D	helicase
C1O57_05350	ENOG4105CGH	5'-nucleotidase
C1O57_05355	ENOG4105K6T	rare lipoprotein A
C1O57_05360	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C1O57_05365	ENOG41082A0	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C1O57_05375	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C1O57_05380	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C1O57_05385	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
C1O57_05390	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C1O57_05395	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C1O57_05400	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C1O57_05405	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C1O57_05410	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C1O57_05425	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C1O57_05440	ENOG4105K64	Glycosyl transferase, family 2
C1O57_05450	ENOG4105K64	Glycosyl transferase, family 2
C1O57_05465	ENOG4105K64	Glycosyl transferase, family 2
C1O57_05470	ENOG4108Z0Z	intracellular protease Pfpi family
C1O57_05475	ENOG4105C7S	Dehydrogenase
C1O57_05480	ENOG4105CE4	GlcNAc 6-P deacetylase
C1O57_05485	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
C1O57_05510	ENOG4105ENH	Sulfatase
C1O57_05515	ENOG41084NN	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C1O57_05520	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C1O57_05525	ENOG4105CHV	Transcription elongation factor NusA
C1O57_05530	ENOG4105CGK	Exodeoxyribonuclease III
C1O57_05535	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C1O57_05560	ENOG4105IDI	abc transporter atp-binding protein
C1O57_05585	ENOG4105VFU	Rna-binding protein
C1O57_05590	ENOG4105D3Q	Sugar transferase
C1O57_05610	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C1O57_05615	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
C1O57_05620	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
C1O57_05625	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C1O57_05640	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C1O57_05665	ENOG4105E33	succinate dehydrogenase
C1O57_05705	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C1O57_05725	ENOG4107TAE	Glycosyl transferase (Group 1
C1O57_05750	ENOG4105K64	Glycosyl transferase, family 2
C1O57_05755	ENOG4105K64	Glycosyl transferase, family 2
C1O57_05760	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C1O57_05765	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C1O57_05770	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C1O57_05835	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
C1O57_05865	ENOG4107QRG	dna polymerase iii
C1O57_05870	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C1O57_05885	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C1O57_05890	ENOG4105CGK	Exodeoxyribonuclease III
C1O57_05955	ENOG4107YVC	modification (methylase)
C1O57_05965	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C1O57_05975	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C1O57_05985	ENOG4105CAT	Cytidine monophosphate kinase
C1O57_05995	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C1O57_06015	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C1O57_06020	ENOG4108Z03	MAF-like protein
C1O57_06025	ENOG4105C7B	Threonine dehydratase
C1O57_06045	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
C1O57_06050	ENOG4105DGA	Diaminopimelate dehydrogenase
C1O57_06075	ENOG4105SYT	Methylenetetrahydrofolate reductase
C1O57_06080	ENOG4107R11	Transcriptional regulator
C1O57_06085	ENOG4105WPN	DNA integration recombination invertion protein
C1O57_06105	ENOG4107RAN	Peptidase, M16
C1O57_06110	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C1O57_06130	ENOG4105DXN	mazG family
C1O57_06140	ENOG41081UC	Inherit from COG: Competence protein
C1O57_06160	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C1O57_06175	ENOG4105CP7	Triose-phosphate isomerase
C1O57_06185	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C1O57_06190	ENOG4105CDH	Citrulline--aspartate ligase
C1O57_06210	ENOG41082R9	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C1O57_06220	ENOG4105C37	(CBS) domain
C1O57_06230	ENOG41080R2	UPF0102 protein
C1O57_06240	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C1O57_06265	ENOG4105CSM	endonuclease III
C1O57_06280	ENOG4109015	Biopolymer transport protein exbD tolR
C1O57_06310	ENOG4105C03	ribonuclease
C1O57_06315	ENOG4105DFF	Rod shape-determining protein mreb
C1O57_06330	ENOG4105CN9	Peptidase m42 family protein
C1O57_06340	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
C1O57_06345	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
C1O57_06355	ENOG4107QPR	SAICAR synthetase
C1O57_06365	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C1O57_06370	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C1O57_06375	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C1O57_06380	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C1O57_06390	ENOG4105D7W	serine acetyltransferase
C1O57_06410	ENOG4105C2X	Arabinose 5-phosphate isomerase
C1O57_06415	ENOG4105D06	uba thif-type nad fad binding protein
C1O57_06455	ENOG4105CJN	penicillin-binding protein
C1O57_06465	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
C1O57_06480	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C1O57_06485	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C1O57_06490	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C1O57_06495	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C1O57_06500	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C1O57_06520	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
C1O57_06570	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C1O57_06580	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
C1O57_06590	ENOG4105DIW	FeS assembly protein SUFB
C1O57_06595	ENOG4105C3K	feS assembly ATPase SufC
C1O57_06600	ENOG4105G5W	regulator Fur family
C1O57_06605	ENOG4105K46	50S ribosomal protein l27
C1O57_06610	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C1O57_06615	ENOG4105K8N	protein family UPF0079, ATPase
C1O57_06620	ENOG4107XM9	(LipO)protein
C1O57_06630	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
C1O57_06640	ENOG4105CSR	polyphosphate kinase 2
C1O57_06655	ENOG4106H78	methyltransferase
C1O57_06670	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C1O57_06675	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C1O57_06680	ENOG4105C3J	Cysteine desulfurase
C1O57_06685	ENOG4105C3J	Cysteine desulfurase
C1O57_06700	ENOG4107EDW	L-fucose operon activator
C1O57_06705	ENOG4105CSR	polyphosphate kinase 2
C1O57_06725	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C1O57_06745	ENOG4105EMN	RNA polymerase sigma factor
C1O57_06750	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C1O57_06755	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C1O57_06760	ENOG4105NQG	DoxX
C1O57_06790	ENOG41061MV	Arylsulfatase
C1O57_06805	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1O57_06815	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
C1O57_06820	ENOG4105C3G	gtp-binding protein
C1O57_06825	ENOG4105DZ1	carboxypeptidase
C1O57_06830	ENOG4105C79	DNA protecting protein DprA
C1O57_06845	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C1O57_06850	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1O57_06855	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C1O57_06860	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C1O57_06880	ENOG4108W0I	acetyltransferase
C1O57_06890	ENOG4105CEV	competence damage-inducible protein
C1O57_06900	ENOG4105CDU	Replicative dna helicase
C1O57_06905	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C1O57_06910	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C1O57_06915	ENOG410803B	Involved in the transcription termination process (By similarity)
C1O57_06920	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C1O57_06925	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C1O57_06930	ENOG4105CX6	glutaminyL-tRNA synthetase
C1O57_06940	ENOG4105C54	Major Facilitator superfamily
C1O57_06955	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C1O57_06960	ENOG4108775	30S ribosomal protein S21
C1O57_06965	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C1O57_06970	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C1O57_06975	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C1O57_06980	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
C1O57_07010	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C1O57_07020	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C1O57_07025	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C1O57_07045	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C1O57_07050	ENOG4105E2D	ec 3.2.1.52
C1O57_07065	ENOG4106855	Competence protein
C1O57_07085	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C1O57_07090	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C1O57_07125	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C1O57_07130	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C1O57_07135	ENOG4105C37	(CBS) domain
C1O57_07140	ENOG4105C37	(CBS) domain
C1O57_07160	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C1O57_07165	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C1O57_07170	ENOG4105C0B	DNA polymerase III (alpha subunit)
C1O57_07180	ENOG4105CVK	Glutamate decarboxylase
C1O57_07195	ENOG4105E2D	ec 3.2.1.52
C1O57_07210	ENOG4108JUA	Transcriptional regulator
C1O57_07225	ENOG4105EMU	Dehydrogenase
C1O57_07235	ENOG4108IJ6	ABC transporter
C1O57_07250	ENOG4107T0D	ABC, transporter
C1O57_07290	ENOG4108IPT	Naphthoate synthase
C1O57_07315	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C1O57_07320	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C1O57_07385	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C1O57_07400	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C1O57_07435	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C1O57_07445	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C1O57_07465	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C1O57_07470	ENOG4108M8S	permease YjgP YjgQ family protein
C1O57_07485	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C1O57_07500	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C1O57_07505	ENOG4105BZU	Histidine kinase
C1O57_07515	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C1O57_07525	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C1O57_07530	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C1O57_07535	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C1O57_07540	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C1O57_07545	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C1O57_07550	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C1O57_07555	ENOG4108542	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C1O57_07560	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1O57_07565	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C1O57_07575	ENOG41080P9	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C1O57_07580	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C1O57_07585	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C1O57_07590	ENOG41082SA	50s ribosomal protein l29
C1O57_07595	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C1O57_07600	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C1O57_07610	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C1O57_07615	ENOG4105CNT	hydrolase family 2
C1O57_07665	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C1O57_07670	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C1O57_07675	ENOG4105K6T	rare lipoprotein A
C1O57_07685	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C1O57_07695	ENOG4105VIE	preprotein translocase, subunit YajC
C1O57_07720	ENOG4105K5M	30s ribosomal protein S16
C1O57_07725	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C1O57_07730	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C1O57_07750	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C1O57_07760	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
C1O57_07855	ENOG4105CDU	Replicative dna helicase
C1O57_07870	ENOG4107QWP	ABC-2 type transporter
C1O57_07875	ENOG4107QWP	ABC-2 type transporter
C1O57_07880	ENOG4105CJ1	ABC, transporter
C1O57_07890	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C1O57_07895	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
C1O57_07905	ENOG4105EEI	dihydropteroate synthase
C1O57_07915	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C1O57_07920	ENOG4105CHR	reductase
C1O57_07950	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C1O57_07975	ENOG4105C9M	aspartyl-trna synthetase
C1O57_07980	ENOG4105CUT	histidyl-tRNA synthetase
C1O57_08000	ENOG4105CQS	hydrogenase expression formation protein HypD
C1O57_08025	ENOG4105CFG	Acts as a chaperone (By similarity)
C1O57_08030	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C1O57_08035	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C1O57_08070	ENOG4105D75	Capsular exopolysaccharide family
C1O57_08085	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C1O57_08095	ENOG4105BZA	Phosphoglycerate kinase
C1O57_08110	ENOG4105CGS	Alpha-glucosidase
C1O57_08120	ENOG4107YVC	modification (methylase)
C1O57_08130	ENOG4108JA2	transcriptioN-repair coupling factor
C1O57_08140	ENOG4105DJB	Major Facilitator Superfamily
C1O57_08155	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
C1O57_08160	ENOG4105C6K	Malic enzyme
C1O57_08165	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C1O57_08170	ENOG4105NRA	50s ribosomal protein l31 type b
C1O57_08205	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
C1O57_08210	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C1O57_08235	ENOG4108RCM	Nitroreductase
C1O57_08240	ENOG4105C34	Pseudouridine synthase
C1O57_08245	ENOG4105I08	Pseudouridine synthase
C1O57_08265	ENOG4105CDA	abc transporter atp-binding protein
C1O57_08270	ENOG4105E5Q	amino acid AbC transporter
C1O57_08280	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C1O57_08285	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
C1O57_08305	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C1O57_08335	ENOG4105VZ9	UPF0235 protein
C1O57_08340	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1O57_08345	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C1O57_08350	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C1O57_08360	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
C1O57_08375	ENOG4105CQB	FAD linked oxidase domain protein
C1O57_08400	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C1O57_08405	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C1O57_08415	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C1O57_08420	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C1O57_08425	ENOG4107Q5Z	Binds together with S18 to 16S ribosomal RNA (By similarity)
C1O57_08435	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C1O57_08450	ENOG4105DZ1	carboxypeptidase
C1O57_08455	ENOG4105CTQ	phosphohexokinase
C1O57_08465	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
C1O57_08470	ENOG4105MH8	Thioredoxin disulfide isomerase
C1O57_08480	ENOG4105JKW	Valine--pyruvate aminotransferase
C1O57_08485	ENOG4105DSJ	YicC domain protein
C1O57_08505	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C1O57_08520	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
C1O57_08540	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C1O57_08565	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C1O57_08585	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
C1O57_08595	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C1O57_08600	ENOG4108ZT0	50S ribosomal protein l17
C1O57_08605	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C1O57_08610	ENOG4107YBY	Hydrolase
C1O57_08630	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C1O57_08695	ENOG4105CPC	Aldo Keto reductase
C1O57_08700	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
C1O57_08720	ENOG4105CRQ	synthase (Component I)
C1O57_08725	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C1O57_08730	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C1O57_08735	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
C1O57_08740	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C1O57_08745	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C1O57_08760	ENOG4105DWV	Homoserine O-trans-acetylase
C1O57_08765	ENOG4105YK5	50S ribosomal protein L36
C1O57_08775	ENOG4105F1A	Pyruvate formate-lyase
C1O57_08800	ENOG4108HCJ	Hydrolase
C1O57_08805	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C1O57_08810	ENOG4106UW1	Major Facilitator superfamily
C1O57_08815	ENOG4108SVB	resolvase
C1O57_08855	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C1O57_08860	ENOG4105VJV	50s ribosomal protein L35
C1O57_08865	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C1O57_08885	ENOG4107QKA	exodeoxyribonuclease V beta
C1O57_08900	ENOG410631K	Membrane
C1O57_08905	ENOG4108HED	Type II restriction
C1O57_08910	ENOG4107S85	alpha-2-macroglobulin domain protein
C1O57_08915	ENOG4107QW4	alcohol dehydrogenase
C1O57_08925	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C1O57_08950	ENOG4105BZN	citrate synthase
C1O57_08965	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C1O57_08975	ENOG4108R99	pseudouridine synthase
C1O57_08985	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C1O57_08995	ENOG4105CKK	Glycosyl transferase, family 2
C1O57_09005	ENOG4105D7Q	type ii secretion system
C1O57_09010	ENOG4107QHF	type ii secretion system protein e
C1O57_09015	ENOG4107QHF	type ii secretion system protein e
C1O57_09020	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C1O57_09035	ENOG4105CJR	Integral membrane protein (MviN
C1O57_09040	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C1O57_09055	ENOG4105F32	YngK protein
C1O57_09060	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
C1O57_09065	ENOG4105DVM	PP-loop domain protein
C1O57_09070	ENOG4105C8M	UPF0272 protein
C1O57_09075	ENOG4105EAH	synthase
C1O57_09090	ENOG4105VG1	fes assembly suf system protein
C1O57_09105	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C1O57_09110	ENOG4105C8S	subunit m
C1O57_09120	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C1O57_09125	ENOG4107UFS	subunit j
C1O57_09135	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
C1O57_09140	ENOG4108IEH	NADH dehydrogenase subunit g
C1O57_09145	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
C1O57_09150	ENOG4105GKE	subunit e
C1O57_09155	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C1O57_09165	ENOG4107BJW	polysaccharide deacetylase
C1O57_09175	ENOG4108R6K	riboflavin synthase, subunit alpha
C1O57_09180	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C1O57_09190	ENOG4107S1W	4-alpha-glucanotransferase
C1O57_09200	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
C1O57_09205	ENOG4105F7J	membrane-bound serine protease
C1O57_09210	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C1O57_09215	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C1O57_09220	ENOG4108UQS	dipeptidase
C1O57_09235	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C1O57_09240	ENOG4105CN1	protease
C1O57_09255	ENOG4105CQ7	ATP-dependent helicase
C1O57_09285	ENOG4105GVR	general secretion pathway protein D
C1O57_09300	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C1O57_09325	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
C1O57_09330	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C1O57_09340	ENOG410872P	Binds directly to 16S ribosomal RNA (By similarity)
C1O57_09345	ENOG4107VXZ	Hydrolase
C1O57_09350	ENOG4105C7K	acetolactate synthase
C1O57_09360	ENOG4105DJ4	phosphatidylserine decarboxylase
C1O57_09370	ENOG4105C8T	Leucyl-tRNA synthetase
C1O57_09375	ENOG4105ENH	Sulfatase
C1O57_09390	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
C1O57_09410	ENOG4105CNT	hydrolase family 2
C1O57_09415	ENOG4105D1H	recombination factor protein RarA
C1O57_09420	ENOG4105E2D	ec 3.2.1.52
C1O57_09440	ENOG4105CTQ	phosphohexokinase
C1O57_09475	ENOG4108YZT	Adenosylcobinamide kinase
C1O57_09485	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
C1O57_09490	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C1O57_09495	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C1O57_09500	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C1O57_09510	ENOG4107ENK	receptor
C1O57_09530	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
C1O57_09535	ENOG4107QN2	dihydrolipoyl dehydrogenase
C1O57_09555	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C1O57_09560	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C1O57_09570	ENOG4107WAU	Protein tyrosine phosphatase
C1O57_09590	ENOG410834F	Transcriptional regulator
C1O57_09615	ENOG4108UB4	uncharacterized protein ygjQ
C1O57_09635	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C1O57_09650	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C1O57_09655	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C1O57_09660	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C1O57_09690	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C1O57_09695	ENOG4105CEY	Amp-dependent synthetase and ligase
C1O57_09730	ENOG4108IAJ	Nad-dependent epimerase dehydratase
C1O57_09735	ENOG41065SU	Two-component system sensor kinase
C1O57_09750	ENOG4105D52	delta-aminolevulinic acid dehydratase
C1O57_09765	ENOG4105C22	threonyL-tRNA synthetase
C1O57_09770	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C1O57_09785	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C1O57_09815	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
C1O57_09830	ENOG4105KPE	licD family
C1O57_09835	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
C1O57_09850	ENOG4105KPE	licD family
C1O57_09855	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C1O57_09865	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
C1O57_09870	ENOG4105DBV	ornithine carbamoyltransferase
C1O57_09875	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
C1O57_09880	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C1O57_09885	ENOG41080Z8	PHOSPHOCARRIER protein
C1O57_09890	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
C1O57_09895	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C1O57_09900	ENOG4105DA5	(ABC) transporter
C1O57_09930	ENOG4105CND	Glycosyl transferase, family 2
C1O57_09940	ENOG4105NWN	ApaG protein
C1O57_09945	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
C1O57_09945	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
C1O57_09960	ENOG4108ZB6	transcriptional regulator AsnC family
C1O57_09965	ENOG4105CHM	Aminotransferase
C1O57_09980	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
C1O57_09985	ENOG4105CV8	reductase
C1O57_10015	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1O57_10020	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
C1O57_10025	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
C1O57_10065	ENOG4105C0H	protease
C1O57_10080	ENOG4105EXC	Acyl-transferase
C1O57_10100	ENOG4105C87	Aminotransferase class I and II
C1O57_10115	ENOG4105ENX	hydrolase
C1O57_10120	ENOG4107SET	aldo keto reductase
C1O57_10125	ENOG4105DIN	metallophosphoesterase
C1O57_10145	ENOG4105VUF	Transcriptional regulator
C1O57_10170	ENOG4105E2D	ec 3.2.1.52
C1O57_10190	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
C1O57_10210	ENOG4105VB6	UPF0109 protein
C1O57_10220	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C1O57_10255	ENOG4105C2I	pirin domain protein
C1O57_10275	ENOG4105CMG	Carbohydrate kinase
C1O57_10280	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
C1O57_10285	ENOG4105EDR	glucose galactose transporter
C1O57_10330	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C1O57_10350	ENOG4105C0H	protease
C1O57_10360	ENOG4105EMK	carboxylate amino acid amine transporter
C1O57_10370	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C1O57_10385	ENOG4108J59	Extracellular solute-binding protein, family 5
C1O57_10395	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
C1O57_10420	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C1O57_10425	ENOG4105CKU	formyltetrahydrofolate synthetase
C1O57_10430	ENOG4108XC3	NADH ubiquinone oxidoreductase
C1O57_10435	ENOG4107QNG	Phosphoribosylglycinamide synthetase
C1O57_10455	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C1O57_10495	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
C1O57_10510	ENOG4105NQN	cytochrome C
C1O57_10525	ENOG4105MEV	Acyl-transferase
C1O57_10530	ENOG4108HMX	isocitrate dehydrogenase (NADP)
C1O57_10545	ENOG4105CY0	Metallo-Beta-Lactamase
C1O57_10550	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C1O57_10555	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C1O57_10560	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C1O57_10570	ENOG4105D64	Mechanosensitive ion channel
C1O57_10575	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C1O57_10580	ENOG410845M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes (By similarity)
C1O57_10585	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C1O57_10605	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C1O57_10615	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C1O57_10625	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C1O57_10640	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C1O57_10655	ENOG4105DIN	metallophosphoesterase
C1O57_10675	ENOG4105DVP	Adenine-specific
C1O57_10680	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C1O57_10705	ENOG4108JB8	alcohol dehydrogenase
C1O57_10710	ENOG4105WMR	Protein CrcB homolog
C1O57_10725	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C1O57_10740	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C1O57_10770	ENOG4105CRE	cytochrome C
C1O57_10785	ENOG4108IPW	abc transporter atp-binding protein
C1O57_10790	ENOG4105CM4	permease protein
C1O57_10795	ENOG4105DHS	permease protein
C1O57_10830	ENOG4105C2M	dna polymerase I
C1O57_10845	ENOG4105C83	adenylosuccinate lyase
C1O57_10850	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C1O57_10910	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C1O57_10915	ENOG4108Z66	YbaK ebsC protein
C1O57_10955	ENOG4105DWK	Membrane
C1O57_10960	ENOG4107XM3	UPF0442 protein
C1O57_10965	ENOG4105CVR	type I restriction-modification system
C1O57_10975	ENOG41082EK	Restriction modification system DNA (Specificity
C1O57_10985	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C1O57_10990	ENOG41082EK	Restriction modification system DNA (Specificity
C1O57_10995	ENOG4105DZR	Type I site-specific deoxyribonuclease
C1O57_11010	ENOG4105CFH	Aspartokinase
C1O57_11030	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C1O57_11040	ENOG4105E2X	shikimate dehydrogenase
C1O57_11050	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C1O57_11055	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C1O57_11065	ENOG4107QP8	phosphohexose isomerase
C1O57_11075	ENOG4105DR4	Methyltransferase
C1O57_11085	ENOG4105D5P	Methylmalonyl-coA mutase
C1O57_11120	ENOG4105II7	pyrroline-5-carboxylate reductase
C1O57_11125	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C1O57_11140	ENOG4105D9P	serine threonine protein kinase
C1O57_11150	ENOG4105C0F	tryptophanase EC 4.1.99.1
C1O57_11165	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C1O57_11170	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C1O57_11190	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C1O57_11220	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
C1O57_11235	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C1O57_11240	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C1O57_11255	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C1O57_11260	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C1O57_11280	ENOG4105E2D	ec 3.2.1.52
C1O57_11285	ENOG4105E2D	ec 3.2.1.52
C1O57_11290	ENOG4105DJT	lAO AO transport system ATPase
C1O57_11310	ENOG41081ID	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C1O57_11315	ENOG4105C1J	atp-dependent rna helicase
C1O57_11320	ENOG4105C5X	domain protein
C1O57_11325	ENOG4105EKE	dihydroorotase
C1O57_11340	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C1O57_11350	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
C1O57_11360	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C1O57_11365	ENOG4107QSA	Oxaloacetate decarboxylase
C1O57_11390	ENOG4107QI1	Mate efflux family protein
C1O57_11410	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C1O57_11420	ENOG4105DGW	oligopeptidase A
C1O57_11425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C1O57_11435	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
C1O57_11460	ENOG4105U6W	MutT NUDIX family protein
C1O57_11500	ENOG4105D82	Glutamate dehydrogenase
C1O57_11510	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C1O57_11515	ENOG4107T5V	SNARE associated Golgi
C1O57_11590	ENOG4105C26	Dehydrogenase
C1O57_11610	ENOG4105CH6	catalase
C1O57_11625	ENOG4105CRE	cytochrome C
C1O57_11630	ENOG4108RAC	Rubrerythrin
C1O57_11635	ENOG41068WN	
C1O57_11645	ENOG4105CNU	cell division protein FtsK
C1O57_11665	ENOG4108QV3	biosynthesis protein
C1O57_11675	ENOG4105D3Q	Sugar transferase
C1O57_11700	ENOG4105K64	Glycosyl transferase, family 2
C1O57_11715	ENOG4105E2K	Glycosyl transferase (Group 1
C1O57_11720	ENOG4107T8Q	Glycosyl transferase (Group 1
C1O57_11745	ENOG4105ECJ	Glycosyl Transferase
C1O57_11770	ENOG4105EXC	Acyl-transferase
C1O57_11795	ENOG4105C87	Aminotransferase class I and II
C1O57_11800	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C1O57_11805	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C1O57_11815	ENOG4105C6K	Malic enzyme
C1O57_11830	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C1O57_11835	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C1O57_11860	ENOG4105CSA	Coproporphyrinogen iii oxidase
C1O57_11895	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C1O57_11900	ENOG4105CPQ	Dehydrogenase
C1O57_11915	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C1O57_11925	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C1O57_11930	ENOG4105BZ4	penicillin-binding protein
C1O57_11945	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C1O57_11965	ENOG4105E3S	small subunit
C1O57_11970	ENOG4105DPX	Hydrogenase, large subunit
C1O57_11980	ENOG4108USZ	hydrogenase
C1O57_11985	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
C1O57_12015	ENOG4108RCM	Nitroreductase
C1O57_12020	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C1O57_12045	ENOG4107GFK	fumarate
C1O57_12065	ENOG4105E2D	ec 3.2.1.52
C1O57_12075	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C1O57_12095	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
C1O57_12100	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C1O57_12115	ENOG4105CEY	Amp-dependent synthetase and ligase
C1O57_12140	ENOG4105DGW	oligopeptidase A
C1O57_12150	ENOG4105C75	arginyL-tRNA synthetase
C1O57_12185	ENOG4105FA0	parb-like partition protein
C1O57_12205	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C1O57_12210	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C1O57_12215	ENOG4107QZM	n-acetylglutamate synthase
C1O57_12230	ENOG4108YZ4	nudix hydrolase