locus-tag	class	description
CUC06_00005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUC06_00010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_00025	COG1121	(ABC) transporter
CUC06_00030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUC06_00035	COG3880	PFAM UvrB UvrC protein
CUC06_00040	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CUC06_00045	COG0542	response to heat
CUC06_00055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CUC06_00060	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUC06_00065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC06_00080	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CUC06_00080	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CUC06_00090	COG0180	Tryptophanyl-tRNA synthetase
CUC06_00100	COG1692	metallophosphoesterase
CUC06_00110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CUC06_00175	COG0515	serine threonine protein kinase
CUC06_00265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUC06_00270	COG2816	NAD+ diphosphatase activity
CUC06_00280	COG0156	8-amino-7-oxononanoate synthase activity
CUC06_00290	COG1192	Involved in chromosome partitioning
CUC06_00295	COG0515	serine threonine protein kinase
CUC06_00295	COG3266	domain, Protein
CUC06_00335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CUC06_00345	COG3189	MarR family transcriptional regulator
CUC06_00355	COG0181	hydroxymethylbilane synthase activity
CUC06_00360	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CUC06_00370	COG1469	GTP cyclohydrolase I activity
CUC06_00375	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CUC06_00380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CUC06_00385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CUC06_00390	COG1940	carbohydrate kinase activity
CUC06_00405	COG0494	nUDIX hydrolase
CUC06_00410	COG1566	PFAM secretion protein HlyD family protein
CUC06_00415	COG0577	efflux transmembrane transporter activity
CUC06_00415	COG1136	(ABC) transporter
CUC06_00420	COG1136	(ABC) transporter
CUC06_00420	COG0577	efflux transmembrane transporter activity
CUC06_00425	COG1538	Outer membrane efflux protein
CUC06_00440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC06_00485	COG1720	tRNA m6t6A37 methyltransferase activity
CUC06_00490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CUC06_00495	COG0540	Belongs to the ATCase OTCase family
CUC06_00500	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CUC06_00515	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CUC06_00530	COG0750	zinc metalloprotease
CUC06_00540	COG3119	arylsulfatase activity
CUC06_00550	COG1918	ferrous iron import across plasma membrane
CUC06_00550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CUC06_00620	COG1475	DNA binding
CUC06_00655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CUC06_00675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC06_00680	COG0601	transmembrane transport
CUC06_00730	COG0849	cell division
CUC06_00740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC06_00745	COG1132	(ABC) transporter
CUC06_00750	COG1132	(ABC) transporter
CUC06_00765	COG1127	ABC transporter
CUC06_00770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CUC06_00805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC06_00820	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CUC06_00825	COG0504	CTP synthase activity
CUC06_00830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC06_00855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC06_00865	COG1322	Protein conserved in bacteria
CUC06_00870	COG0546	phosphoglycolate phosphatase activity
CUC06_00875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC06_00885	COG4591	ABC-type transport system involved in lipoprotein release permease component
CUC06_00885	COG4591	ABC-type transport system involved in lipoprotein release permease component
CUC06_00905	COG3209	COG3209 Rhs family protein
CUC06_00910	COG3209	COG3209 Rhs family protein
CUC06_00910	COG4104	PAAR repeat-containing protein
CUC06_00935	COG3209	COG3209 Rhs family protein
CUC06_00970	COG2234	aminopeptidase activity
CUC06_00975	COG2755	lipolytic protein G-D-S-L family
CUC06_00975	COG0657	acetylesterase activity
CUC06_00980	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CUC06_01000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUC06_01020	COG0335	large ribosomal subunit rRNA binding
CUC06_01030	COG0346	lactoylglutathione lyase activity
CUC06_01045	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CUC06_01050	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CUC06_01060	COG0427	acetyl-CoA hydrolase
CUC06_01075	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CUC06_01085	COG0205	6-phosphofructokinase activity
CUC06_01095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC06_01100	COG0028	Belongs to the TPP enzyme family
CUC06_01120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUC06_01135	COG0471	metal ion transport
CUC06_01145	COG0351	phosphomethylpyrimidine kinase
CUC06_01210	COG0242	peptide deformylase activity
CUC06_01215	COG1063	alcohol dehydrogenase
CUC06_01225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUC06_01230	COG1393	Belongs to the ArsC family
CUC06_01235	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CUC06_01255	COG1187	pseudouridine synthase activity
CUC06_01265	COG0336	Belongs to the RNA methyltransferase TrmD family
CUC06_01270	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CUC06_01280	COG0539	negative regulation of cytoplasmic translation
CUC06_01330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CUC06_01335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUC06_01340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CUC06_01345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC06_01385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC06_01465	COG3015	lipoprotein NlpE involved in copper resistance
CUC06_01540	COG0305	Participates in initiation and elongation during chromosome replication
CUC06_01650	COG0662	Cupin 2, conserved barrel domain protein
CUC06_01650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CUC06_01660	COG0416	fatty acid biosynthetic process
CUC06_01665	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CUC06_01675	COG0537	adenosine 5'-monophosphoramidase activity
CUC06_01680	COG0009	L-threonylcarbamoyladenylate synthase
CUC06_01685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CUC06_01690	COG0228	four-way junction DNA binding
CUC06_01720	COG1862	Preprotein translocase
CUC06_01725	COG0343	queuine tRNA-ribosyltransferase activity
CUC06_01730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CUC06_01740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUC06_01745	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CUC06_01750	COG0776	regulation of translation
CUC06_01785	COG0811	peptide transport
CUC06_01805	COG3250	beta-galactosidase activity
CUC06_01810	COG0525	valine-tRNA ligase activity
CUC06_01820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CUC06_01825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CUC06_01830	COG0255	Belongs to the universal ribosomal protein uL29 family
CUC06_01835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CUC06_01840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CUC06_01845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CUC06_01855	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CUC06_01860	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CUC06_01865	COG0089	rRNA binding
CUC06_01870	COG0088	Forms part of the polypeptide exit tunnel
CUC06_01875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CUC06_01880	COG0051	transcription antitermination factor activity, RNA binding
CUC06_01885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CUC06_01890	COG0049	tRNA binding
CUC06_01895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CUC06_01905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CUC06_01915	COG3852	Histidine kinase
CUC06_01920	COG2204	response regulator
CUC06_01930	COG1722	exodeoxyribonuclease VII activity
CUC06_01935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CUC06_01950	COG0795	lipopolysaccharide-transporting ATPase activity
CUC06_01955	COG1160	GTP binding
CUC06_01960	COG0444	Belongs to the ABC transporter superfamily
CUC06_01975	COG0577	efflux transmembrane transporter activity
CUC06_01975	COG1136	(ABC) transporter
CUC06_01985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CUC06_02035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CUC06_02045	COG0799	negative regulation of ribosome biogenesis
CUC06_02050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC06_02115	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CUC06_02130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CUC06_02140	COG4221	oxidoreductase activity
CUC06_02160	COG0038	chloride channel
CUC06_02170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_02185	COG0076	glutamate decarboxylase activity
CUC06_02200	COG0167	dihydroorotate dehydrogenase activity
CUC06_02205	COG0352	thiamine-phosphate diphosphorylase activity
CUC06_02225	COG1253	flavin adenine dinucleotide binding
CUC06_02230	COG1253	flavin adenine dinucleotide binding
CUC06_02235	COG1185	polyribonucleotide nucleotidyltransferase activity
CUC06_02240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CUC06_02270	COG0101	tRNA pseudouridine synthase activity
CUC06_02275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CUC06_02295	COG4968	Prepilin-type N-terminal cleavage methylation domain
CUC06_02310	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_02315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CUC06_02335	COG1136	(ABC) transporter
CUC06_02340	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CUC06_02350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC06_02360	COG1116	anion transmembrane transporter activity
CUC06_02375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_02380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CUC06_02385	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CUC06_02400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CUC06_02405	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CUC06_02415	COG2814	Major facilitator Superfamily
CUC06_02425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC06_02430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUC06_02430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUC06_02435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CUC06_02440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CUC06_02445	COG0552	protein localization to endoplasmic reticulum
CUC06_02450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CUC06_02470	COG1546	Belongs to the CinA family
CUC06_02470	COG1058	Belongs to the CinA family
CUC06_02480	COG0456	acetyltransferase
CUC06_02505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CUC06_02510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CUC06_02515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CUC06_02520	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUC06_02535	COG0758	DNA mediated transformation
CUC06_02540	COG1686	Belongs to the peptidase S11 family
CUC06_02545	COG0012	GTP binding
CUC06_02560	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUC06_02560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUC06_02575	COG3119	arylsulfatase activity
CUC06_02600	COG2259	Doxx family
CUC06_02605	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CUC06_02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUC06_02655	COG2326	polyphosphate kinase activity
CUC06_02660	COG1349	DNA-binding transcription factor activity
CUC06_02680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUC06_02685	COG1162	GTPase activity
CUC06_02700	COG0742	ribosomal rna small subunit methyltransferase
CUC06_02715	COG2326	polyphosphate kinase activity
CUC06_02725	COG5434	Belongs to the glycosyl hydrolase 28 family
CUC06_02735	COG1073	alpha beta
CUC06_02740	COG0802	atpase or kinase
CUC06_02750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CUC06_02755	COG0735	belongs to the Fur family
CUC06_02760	COG0396	ATPase activity
CUC06_02765	COG0719	Fe-S assembly protein
CUC06_02770	COG0719	Fe-S assembly protein
CUC06_02785	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CUC06_02830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CUC06_02850	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CUC06_02855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CUC06_02860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CUC06_02865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CUC06_02870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CUC06_02875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CUC06_02885	COG0356	it plays a direct role in the translocation of protons across the membrane
CUC06_02935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CUC06_02970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CUC06_02975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CUC06_02980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUC06_02990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CUC06_03000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUC06_03005	COG0047	phosphoribosylformylglycinamidine synthase activity
CUC06_03015	COG1363	Peptidase, m42
CUC06_03030	COG1077	Cell shape determining protein MreB Mrl
CUC06_03035	COG1530	ribonuclease E activity
CUC06_03065	COG0848	biopolymer transport protein
CUC06_03080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUC06_03105	COG0134	indole-3-glycerol-phosphate synthase activity
CUC06_03110	COG0792	nuclease activity
CUC06_03120	COG1253	flavin adenine dinucleotide binding
CUC06_03130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CUC06_03145	COG0137	argininosuccinate synthase activity
CUC06_03160	COG0149	triose-phosphate isomerase activity
CUC06_03195	COG1040	competence protein
CUC06_03205	COG3956	TIGRFAM MazG family protein
CUC06_03230	COG1663	tetraacyldisaccharide 4'-kinase activity
CUC06_03240	COG0612	Peptidase, M16
CUC06_03260	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUC06_03265	COG0583	DNA-binding transcription factor activity
CUC06_03295	COG0673	inositol 2-dehydrogenase activity
CUC06_03300	COG3034	peptidoglycan biosynthetic process
CUC06_03320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUC06_03325	COG0424	maF-like protein
CUC06_03330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUC06_03360	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CUC06_03370	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CUC06_03380	COG0571	ribonuclease III activity
CUC06_03395	COG0708	Exodeoxyribonuclease III
CUC06_03400	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CUC06_03415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CUC06_03435	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CUC06_03450	COG2226	methyltransferase
CUC06_03460	COG2076	Multidrug Resistance protein
CUC06_03530	COG2255	four-way junction helicase activity
CUC06_03535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CUC06_03540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CUC06_03545	COG1215	transferase activity, transferring glycosyl groups
CUC06_03550	COG1216	Glycosyl transferase, family 2
CUC06_03550	COG0463	Glycosyl transferase, family 2
CUC06_03575	COG0438	transferase activity, transferring glycosyl groups
CUC06_03585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CUC06_03595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CUC06_03605	COG0482	sulfurtransferase activity
CUC06_03610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CUC06_03620	COG2860	membrane
CUC06_03625	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CUC06_03630	COG2001	Belongs to the MraZ family
CUC06_03635	COG0275	rRNA processing
CUC06_03645	COG0768	penicillin binding
CUC06_03650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUC06_03655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUC06_03660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUC06_03665	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CUC06_03675	COG0772	Belongs to the SEDS family
CUC06_03680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CUC06_03685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUC06_03690	COG1181	Belongs to the D-alanine--D-alanine ligase family
CUC06_03700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CUC06_03705	COG0860	N-Acetylmuramoyl-L-alanine amidase
CUC06_03710	COG0321	lipoyl(octanoyl) transferase activity
CUC06_03715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CUC06_03720	COG0066	3-isopropylmalate dehydratase activity
CUC06_03730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC06_03740	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CUC06_03750	COG4608	Belongs to the ABC transporter superfamily
CUC06_03760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CUC06_03775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CUC06_03790	COG1137	ATPase activity
CUC06_03800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUC06_03830	COG0017	Asparaginyl-tRNA synthetase
CUC06_03840	COG3118	belongs to the thioredoxin family
CUC06_03885	COG0583	DNA-binding transcription factor activity
CUC06_03890	COG2855	membrane
CUC06_03895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CUC06_03910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUC06_03920	COG0602	queuosine metabolic process
CUC06_03925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CUC06_03930	COG0217	transcriptional regulatory protein
CUC06_03935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CUC06_03940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC06_03940	COG4651	solute:proton antiporter activity
CUC06_03950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CUC06_03955	COG4864	UPF0365 protein
CUC06_03965	COG2022	thiamine diphosphate biosynthetic process
CUC06_03970	COG0531	amino acid
CUC06_03980	COG0628	permease
CUC06_03985	COG0019	diaminopimelate decarboxylase activity
CUC06_03990	COG0191	fructose-bisphosphate aldolase activity
CUC06_04030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CUC06_04075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUC06_04080	COG0516	GMP reductase activity
CUC06_04080	COG0517	IMP dehydrogenase activity
CUC06_04085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CUC06_04085	COG0519	Catalyzes the synthesis of GMP from XMP
CUC06_04110	COG0546	phosphoglycolate phosphatase activity
CUC06_04135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUC06_04150	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CUC06_04155	COG0196	riboflavin kinase activity
CUC06_04160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUC06_04175	COG1408	metallophosphoesterase
CUC06_04185	COG1216	Glycosyl transferase, family 2
CUC06_04185	COG1442	glycosyl transferase family 8
CUC06_04195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC06_04200	COG1216	Glycosyl transferase, family 2
CUC06_04220	COG2755	lipolytic protein G-D-S-L family
CUC06_04220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CUC06_04235	COG0471	metal ion transport
CUC06_04235	COG0490	domain, Protein
CUC06_04280	COG0588	phosphoglycerate mutase activity
CUC06_04285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CUC06_04295	COG0477	Major facilitator Superfamily
CUC06_04300	COG1607	acyl-coa hydrolase
CUC06_04310	COG1028	Short-chain dehydrogenase reductase Sdr
CUC06_04320	COG1525	nuclease
CUC06_04335	COG1475	DNA binding
CUC06_04340	COG3969	phosphoadenosine phosphosulfate
CUC06_04355	COG0473	3-isopropylmalate dehydrogenase activity
CUC06_04390	COG0535	radical SAM domain protein
CUC06_04405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CUC06_04410	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CUC06_04420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CUC06_04440	COG1733	regulation of RNA biosynthetic process
CUC06_04450	COG0107	imidazoleglycerol-phosphate synthase activity
CUC06_04460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUC06_04470	COG1643	Atp-dependent helicase
CUC06_04475	COG0440	acetolactate synthase activity
CUC06_04480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC06_04490	COG0445	tRNA wobble uridine modification
CUC06_04495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC06_04495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC06_04500	COG0592	DNA-directed DNA polymerase activity
CUC06_04525	COG0791	NLP P60 protein
CUC06_04525	COG1388	LysM domain
CUC06_04530	COG0084	hydrolase, TatD family'
CUC06_04540	COG3250	beta-galactosidase activity
CUC06_04555	COG2205	protein histidine kinase activity
CUC06_04560	COG0745	RESPONSE REGULATOR receiver
CUC06_04570	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CUC06_04595	COG0542	response to heat
CUC06_04645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CUC06_04655	COG0659	secondary active sulfate transmembrane transporter activity
CUC06_04660	COG0165	Argininosuccinate lyase
CUC06_04675	COG0148	phosphopyruvate hydratase activity
CUC06_04680	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CUC06_04690	COG3481	metal-dependent phosphohydrolase, HD sub domain
CUC06_04700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CUC06_04705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CUC06_04770	COG0490	domain, Protein
CUC06_04770	COG2985	domain, Protein
CUC06_04785	COG0471	metal ion transport
CUC06_04810	COG2194	sulfuric ester hydrolase activity
CUC06_04820	COG1592	Rubrerythrin
CUC06_04830	COG1363	Peptidase, m42
CUC06_04835	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_04845	COG1785	Belongs to the alkaline phosphatase family
CUC06_04850	COG1970	mechanosensitive ion channel activity
CUC06_04855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUC06_04865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CUC06_04875	COG2217	Heavy metal translocating P-type atpase
CUC06_04880	COG0497	DNA recombination
CUC06_04885	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CUC06_04885	COG0321	lipoyl(octanoyl) transferase activity
CUC06_04890	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CUC06_04920	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC06_04925	COG0022	dehydrogenase e1 component
CUC06_04930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CUC06_04945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC06_04950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC06_04955	COG3210	domain, Protein
CUC06_05005	COG5632	N-Acetylmuramoyl-L-alanine amidase
CUC06_05005	COG3409	Peptidoglycan-binding domain 1 protein
CUC06_05010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CUC06_05040	COG1690	Belongs to the RtcB family
CUC06_05050	COG2814	Major facilitator Superfamily
CUC06_05060	COG2096	Adenosyltransferase
CUC06_05070	COG0557	exoribonuclease II activity
CUC06_05095	COG0826	peptidase U32
CUC06_05100	COG0285	dihydrofolate synthase activity
CUC06_05115	COG0673	inositol 2-dehydrogenase activity
CUC06_05120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CUC06_05125	COG0737	Belongs to the 5'-nucleotidase family
CUC06_05135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUC06_05140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CUC06_05150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CUC06_05155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CUC06_05160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CUC06_05165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CUC06_05170	COG0200	Binds to the 23S rRNA
CUC06_05180	COG0563	adenylate kinase activity
CUC06_05185	COG0024	Methionine aminopeptidase
CUC06_05200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CUC06_05205	COG1442	glycosyl transferase family 8
CUC06_05215	COG1216	Glycosyl transferase, family 2
CUC06_05225	COG1216	Glycosyl transferase, family 2
CUC06_05240	COG1216	Glycosyl transferase, family 2
CUC06_05245	COG0693	protein deglycase activity
CUC06_05250	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC06_05260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUC06_05275	COG1966	Carbon starvation protein
CUC06_05285	COG3119	arylsulfatase activity
CUC06_05290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CUC06_05295	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CUC06_05300	COG0195	Participates in both transcription termination and antitermination
CUC06_05305	COG0708	Exodeoxyribonuclease III
CUC06_05310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CUC06_05315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CUC06_05320	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUC06_05330	COG1131	(ABC) transporter
CUC06_05330	COG0842	Transport permease protein
CUC06_05330	COG1716	ATPase activity
CUC06_05350	COG0724	RNA recognition motif
CUC06_05355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CUC06_05375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CUC06_05385	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CUC06_05390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC06_05405	COG1490	D-aminoacyl-tRNA deacylase activity
CUC06_05415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CUC06_05420	COG1053	succinate dehydrogenase
CUC06_05470	COG1028	Short-chain dehydrogenase reductase Sdr
CUC06_05485	COG0488	(ABC) transporter
CUC06_05495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CUC06_05505	COG1253	flavin adenine dinucleotide binding
CUC06_05510	COG1028	Short-chain dehydrogenase reductase Sdr
CUC06_05520	COG1073	alpha beta
CUC06_05530	COG0667	Aldo Keto reductase
CUC06_05585	COG2267	carboxylic ester hydrolase activity
CUC06_05590	COG2095	MarC family integral membrane protein
CUC06_05620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUC06_05625	COG0488	(ABC) transporter
CUC06_05695	COG0215	cysteine-tRNA ligase activity
CUC06_05705	COG3119	arylsulfatase activity
CUC06_05720	COG0481	GTPase activity
CUC06_05745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CUC06_05750	COG0085	RNA polymerase activity
CUC06_05755	COG0222	ribosome binding
CUC06_05760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CUC06_05765	COG0081	regulation of translation
CUC06_05770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CUC06_05775	COG0250	Participates in transcription elongation, termination and antitermination
CUC06_05790	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CUC06_05800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CUC06_05810	COG0740	serine-type endopeptidase activity
CUC06_05815	COG0544	peptidyl-prolyl cis-trans isomerase activity
CUC06_05830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CUC06_05850	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC06_05895	COG2226	methyltransferase
CUC06_05900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CUC06_05905	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CUC06_05920	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC06_05920	COG1902	pentaerythritol trinitrate reductase activity
CUC06_05930	COG3119	arylsulfatase activity
CUC06_05935	COG0514	ATP-dependent DNA helicase (RecQ)
CUC06_05960	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CUC06_05965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC06_06015	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CUC06_06030	COG1858	cytochrome C peroxidase
CUC06_06035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CUC06_06040	COG0590	tRNA wobble adenosine to inosine editing
CUC06_06045	COG1940	carbohydrate kinase activity
CUC06_06050	COG2217	Heavy metal translocating P-type atpase
CUC06_06055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CUC06_06085	COG1363	Peptidase, m42
CUC06_06090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CUC06_06100	COG0006	proline dipeptidase activity
CUC06_06105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CUC06_06125	COG5002	protein histidine kinase activity
CUC06_06130	COG0745	RESPONSE REGULATOR receiver
CUC06_06135	COG0129	dihydroxy-acid dehydratase activity
CUC06_06220	COG1368	sulfuric ester hydrolase activity
CUC06_06255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC06_06260	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CUC06_06285	COG0534	Mate efflux family protein
CUC06_06290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUC06_06305	COG1876	peptidase activity
CUC06_06430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CUC06_06435	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CUC06_06440	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CUC06_06445	COG2205	protein histidine kinase activity
CUC06_06465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC06_06480	COG0667	Aldo Keto reductase
CUC06_06485	COG0789	Transcriptional regulator
CUC06_06535	COG0714	Associated with various cellular activities
CUC06_06540	COG2311	Membrane
CUC06_06560	COG1090	epimerase
CUC06_06575	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CUC06_06580	COG1119	ATPase activity
CUC06_06585	COG2186	Transcriptional regulator
CUC06_06610	COG0148	phosphopyruvate hydratase activity
CUC06_06620	COG0436	Aminotransferase
CUC06_06625	COG1477	protein flavinylation
CUC06_06640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CUC06_06655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CUC06_06675	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CUC06_06685	COG1199	ATP-dependent helicase activity
CUC06_06690	COG1122	ATPase activity
CUC06_06715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CUC06_06725	COG0359	binds to the 23S rRNA
CUC06_06730	COG0138	bifunctional purine biosynthesis protein purh
CUC06_06735	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CUC06_06740	COG0736	holo-[acyl-carrier-protein] synthase activity
CUC06_06750	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CUC06_06755	COG3409	Peptidoglycan-binding domain 1 protein
CUC06_06755	COG5632	N-Acetylmuramoyl-L-alanine amidase
CUC06_06760	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUC06_06770	COG0437	4 iron, 4 sulfur cluster binding
CUC06_06790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CUC06_06850	COG0284	orotidine-5'-phosphate decarboxylase activity
CUC06_06870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CUC06_06875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CUC06_06895	COG2003	Belongs to the UPF0758 family
CUC06_06900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CUC06_06900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CUC06_06905	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CUC06_06910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CUC06_06915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CUC06_06920	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CUC06_06925	COG0322	excinuclease ABC activity
CUC06_06930	COG0811	peptide transport
CUC06_06935	COG0848	biopolymer transport protein
CUC06_06945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CUC06_06950	COG0483	inositol monophosphate 1-phosphatase activity
CUC06_06955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CUC06_06965	COG1482	cell wall glycoprotein biosynthetic process
CUC06_06975	COG1757	Na H antiporter
CUC06_06980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC06_06985	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CUC06_06990	COG0505	Belongs to the CarA family
CUC06_06995	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CUC06_07005	COG0070	glutamate synthase
CUC06_07005	COG0069	glutamate synthase activity
CUC06_07005	COG0067	glutamate synthase
CUC06_07010	COG0706	membrane insertase activity
CUC06_07015	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CUC06_07025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CUC06_07045	COG2755	lipolytic protein G-D-S-L family
CUC06_07045	COG0657	acetylesterase activity
CUC06_07055	COG0676	glucose-6-phosphate 1-epimerase activity
CUC06_07075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CUC06_07090	COG1760	l-serine dehydratase
CUC06_07095	COG3118	belongs to the thioredoxin family
CUC06_07095	COG0492	ferredoxin-NADP+ reductase activity
CUC06_07150	COG1408	metallophosphoesterase
CUC06_07160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUC06_07165	COG0545	Peptidyl-prolyl cis-trans isomerase
CUC06_07185	COG0187	DNA topoisomerase II activity
CUC06_07190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CUC06_07200	COG0826	peptidase U32
CUC06_07205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CUC06_07225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC06_07245	COG0529	Catalyzes the synthesis of activated sulfate
CUC06_07245	COG2895	sulfate adenylyltransferase (ATP) activity
CUC06_07250	COG0175	sulfate reduction
CUC06_07255	COG0175	sulfate reduction
CUC06_07280	COG0581	inorganic phosphate transmembrane transporter activity
CUC06_07285	COG0573	inorganic phosphate transmembrane transporter activity
CUC06_07295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUC06_07305	COG2017	converts alpha-aldose to the beta-anomer
CUC06_07320	COG0612	Peptidase, M16
CUC06_07370	COG0233	cytoplasmic translational termination
CUC06_07375	COG0528	UMP kinase activity
CUC06_07380	COG0668	transmembrane transport
CUC06_07385	COG0450	alkyl hydroperoxide reductase
CUC06_07390	COG0733	neurotransmitter:sodium symporter activity
CUC06_07415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUC06_07420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CUC06_07425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUC06_07450	COG0842	Transport permease protein
CUC06_07455	COG0842	Transport permease protein
CUC06_07460	COG1131	(ABC) transporter
CUC06_07470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CUC06_07475	COG1183	phosphatidylcholine synthase activity
CUC06_07485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CUC06_07495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CUC06_07500	COG1028	Short-chain dehydrogenase reductase Sdr
CUC06_07520	COG0156	8-amino-7-oxononanoate synthase activity
CUC06_07545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CUC06_07550	COG0124	histidyl-tRNA synthetase
CUC06_07560	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CUC06_07565	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CUC06_07570	COG0298	carbon dioxide binding
CUC06_07600	COG0443	Heat shock 70 kDa protein
CUC06_07605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CUC06_07610	COG0459	protein refolding
CUC06_07660	COG0632	four-way junction helicase activity
CUC06_07670	COG0126	phosphoglycerate kinase activity
CUC06_07680	COG1082	Xylose isomerase domain protein TIM barrel
CUC06_07690	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CUC06_07700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CUC06_07710	COG2271	Major facilitator Superfamily
CUC06_07725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CUC06_07735	COG0037	tRNA processing
CUC06_07740	COG0254	rRNA binding
CUC06_07775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CUC06_07780	COG0039	L-malate dehydrogenase activity
CUC06_07805	COG0778	Nitroreductase
CUC06_07810	COG0564	pseudouridine synthase activity
CUC06_07835	COG1126	abc transporter atp-binding protein
CUC06_07840	COG0765	amino acid transport
CUC06_07850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CUC06_07855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CUC06_07905	COG1872	DUF167
CUC06_07910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CUC06_07915	COG0484	heat shock protein binding
CUC06_07920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUC06_07930	COG5434	Belongs to the glycosyl hydrolase 28 family
CUC06_07945	COG0277	FAD linked oxidase domain protein
CUC06_07970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CUC06_07975	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CUC06_07985	COG0131	Imidazoleglycerol-phosphate dehydratase
CUC06_07990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CUC06_07995	COG0360	Binds together with S18 to 16S ribosomal RNA
CUC06_08000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CUC06_08015	COG1686	Belongs to the peptidase S11 family
CUC06_08020	COG0205	6-phosphofructokinase activity
CUC06_08030	COG0428	transporter
CUC06_08035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CUC06_08050	COG3977	Valine--pyruvate aminotransferase
CUC06_08055	COG1561	YicC-like family, N-terminal region
CUC06_08065	COG3273	potassium ion transport
CUC06_08065	COG0471	metal ion transport
CUC06_08070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC06_08085	COG1575	Belongs to the MenA family. Type 1 subfamily
CUC06_08120	COG0726	polysaccharide deacetylase
CUC06_08125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUC06_08125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUC06_08150	COG0202	RNA polymerase activity
CUC06_08155	COG0203	ribosomal protein L17
CUC06_08160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUC06_08175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUC06_08190	COG2885	chlorophyll binding
CUC06_08250	COG0667	Aldo Keto reductase
CUC06_08255	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CUC06_08270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUC06_08275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUC06_08280	COG0134	indole-3-glycerol-phosphate synthase activity
CUC06_08285	COG0135	phosphoribosylanthranilate isomerase activity
CUC06_08290	COG0133	tryptophan synthase activity
CUC06_08295	COG0159	tryptophan synthase activity
CUC06_08315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC06_08320	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CUC06_08330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CUC06_08370	COG0561	phosphatase activity
CUC06_08375	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUC06_08380	COG2223	nitrite transmembrane transporter activity
CUC06_08395	COG0556	nucleotide-excision repair
CUC06_08400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CUC06_08405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CUC06_08425	COG1074	ATP-dependent DNA helicase activity
CUC06_08435	COG0697	spore germination
CUC06_08440	COG2373	Large extracellular alpha-helical protein
CUC06_08445	COG1979	alcohol dehydrogenase
CUC06_08455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC06_08480	COG0372	Belongs to the citrate synthase family
CUC06_08500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CUC06_08510	COG1187	pseudouridine synthase activity
CUC06_08520	COG0105	UTP biosynthetic process
CUC06_08525	COG1215	transferase activity, transferring glycosyl groups
CUC06_08530	COG0463	Glycosyl transferase, family 2
CUC06_08540	COG1459	type II secretion system
CUC06_08545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUC06_08555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC06_08570	COG0728	peptidoglycan biosynthetic process
CUC06_08575	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CUC06_08575	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CUC06_08585	COG1649	PFAM Uncharacterised BCR, COG1649
CUC06_08590	COG1691	(AIR) carboxylase
CUC06_08595	COG1606	tRNA processing
CUC06_08600	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CUC06_08605	COG0142	geranyltranstransferase activity
CUC06_08620	COG2151	metal-sulfur cluster biosynthetic enzyme
CUC06_08635	COG1007	ATP synthesis coupled electron transport
CUC06_08640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUC06_08650	COG0713	ATP synthesis coupled electron transport
CUC06_08655	COG0839	Belongs to the complex I subunit 6 family
CUC06_08665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CUC06_08670	COG1034	ATP synthesis coupled electron transport
CUC06_08675	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CUC06_08680	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CUC06_08685	COG0649	NAD binding
CUC06_08695	COG0726	polysaccharide deacetylase
CUC06_08705	COG0307	riboflavin synthase, alpha
CUC06_08715	COG2264	protein methyltransferase activity
CUC06_08730	COG3210	domain, Protein
CUC06_08735	COG1640	4-alpha-glucanotransferase
CUC06_08745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CUC06_08750	COG1030	water channel activity
CUC06_08755	COG0358	DNA primase activity
CUC06_08760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CUC06_08765	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CUC06_08780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CUC06_08785	COG0793	Belongs to the peptidase S41A family
CUC06_08810	COG1643	Atp-dependent helicase
CUC06_08835	COG1450	Type ii and iii secretion system protein
CUC06_08850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CUC06_08870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC06_08875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CUC06_08885	COG0268	Binds directly to 16S ribosomal RNA
CUC06_08890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUC06_08895	COG0028	Belongs to the TPP enzyme family
CUC06_08905	COG0688	phosphatidylethanolamine metabolic process
CUC06_08910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUC06_08915	COG0495	leucyl-tRNA aminoacylation
CUC06_08920	COG3119	arylsulfatase activity
CUC06_08935	COG1166	arginine decarboxylase activity
CUC06_08950	COG3250	beta-galactosidase activity
CUC06_08955	COG3250	beta-galactosidase activity
CUC06_08960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUC06_08965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_08980	COG0205	6-phosphofructokinase activity
CUC06_08995	COG0535	radical SAM domain protein
CUC06_09040	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CUC06_09045	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CUC06_09050	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CUC06_09065	COG4771	TonB-dependent receptor
CUC06_09085	COG0402	S-adenosylhomocysteine deaminase activity
CUC06_09090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC06_09110	COG1294	oxidase, subunit
CUC06_09115	COG1271	oxidase subunit
CUC06_09125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CUC06_09145	COG1846	Transcriptional regulator
CUC06_09175	COG2949	membrane
CUC06_09205	COG0514	ATP-dependent DNA helicase (RecQ)
CUC06_09220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CUC06_09225	COG0045	succinate-CoA ligase (ADP-forming) activity
CUC06_09295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC06_09300	COG2205	protein histidine kinase activity
CUC06_09315	COG0113	porphobilinogen synthase activity
CUC06_09330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CUC06_09335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CUC06_09350	COG0732	type I restriction modification DNA specificity domain
CUC06_09365	COG0732	type I restriction modification DNA specificity domain
CUC06_09375	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CUC06_09400	COG4106	trans-aconitate 2-methyltransferase activity
CUC06_09415	COG3475	LICD family
CUC06_09420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CUC06_09430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CUC06_09435	COG3475	LICD family
CUC06_09440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CUC06_09450	COG2166	iron-sulfur cluster assembly
CUC06_09455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CUC06_09465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUC06_09470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC06_09475	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CUC06_09480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CUC06_09485	COG1131	(ABC) transporter
CUC06_09500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CUC06_09525	COG2967	ApaG domain
CUC06_09530	COG1401	restriction endodeoxyribonuclease activity
CUC06_09530	COG1401	restriction endodeoxyribonuclease activity
CUC06_09545	COG1522	sequence-specific DNA binding
CUC06_09550	COG0436	Aminotransferase
CUC06_09565	COG0423	glycine-tRNA ligase activity
CUC06_09570	COG0656	L-ascorbic acid biosynthetic process
CUC06_09610	COG0714	Associated with various cellular activities
CUC06_09615	COG0154	amidase activity
CUC06_09620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC06_09660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC06_09675	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CUC06_09675	COG2755	lipolytic protein G-D-S-L family
CUC06_09705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CUC06_09715	COG0656	L-ascorbic acid biosynthetic process
CUC06_09725	COG0667	Aldo Keto reductase
CUC06_09730	COG1408	metallophosphoesterase
CUC06_09750	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC06_09755	COG0789	Transcriptional regulator
CUC06_09775	COG0534	Mate efflux family protein
CUC06_09800	COG1091	dTDP-4-dehydrorhamnose reductase activity
CUC06_09815	COG1837	Belongs to the UPF0109 family
CUC06_09825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUC06_09830	COG0363	glucosamine-6-phosphate deaminase activity
CUC06_09845	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CUC06_09855	COG1741	Belongs to the pirin family
CUC06_09870	COG1070	Carbohydrate kinase
CUC06_09885	COG0738	Major facilitator superfamily
CUC06_09900	COG1595	DNA-templated transcription, initiation
CUC06_09925	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CUC06_09945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC06_09950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CUC06_09960	COG3586	endonuclease activity
CUC06_09970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CUC06_09975	COG4608	Belongs to the ABC transporter superfamily
CUC06_09980	COG0444	Belongs to the ABC transporter superfamily
CUC06_09985	COG4166	transmembrane transport
CUC06_09990	COG4239	(ABC) transporter, permease
CUC06_09995	COG0601	transmembrane transport
CUC06_10010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CUC06_10015	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CUC06_10020	COG3738	Protein conserved in bacteria
CUC06_10025	COG0151	Belongs to the GarS family
CUC06_10040	COG0811	peptide transport
CUC06_10050	COG0242	peptide deformylase activity
CUC06_10100	COG3258	Cytochrome c
CUC06_10110	COG3274	enterobacterial common antigen metabolic process
CUC06_10115	COG0538	isocitrate dehydrogenase activity
CUC06_10130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CUC06_10135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CUC06_10140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CUC06_10150	COG0668	transmembrane transport
CUC06_10155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC06_10155	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CUC06_10160	COG0805	protein transport
CUC06_10165	COG1968	undecaprenyl-diphosphatase activity
CUC06_10185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CUC06_10195	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CUC06_10205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CUC06_10215	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CUC06_10225	COG1408	metallophosphoesterase
CUC06_10250	COG4974	Belongs to the 'phage' integrase family
CUC06_10270	COG1454	alcohol dehydrogenase
CUC06_10275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CUC06_10290	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CUC06_10290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CUC06_10295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CUC06_10335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CUC06_10345	COG4607	ABC-type enterochelin transport system periplasmic component
CUC06_10350	COG4604	ABC transporter, ATP-binding protein
CUC06_10355	COG4605	iron ion homeostasis
CUC06_10360	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC06_10395	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUC06_10395	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CUC06_10410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CUC06_10415	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUC06_10450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUC06_10475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUC06_10515	COG0646	methionine synthase
CUC06_10515	COG1410	methionine synthase
CUC06_10520	COG2966	Psort location CytoplasmicMembrane, score
CUC06_10525	COG3610	response to peptide
CUC06_10535	COG0460	homoserine dehydrogenase
CUC06_10540	COG0527	aspartate kinase activity
CUC06_10550	COG5522	Integral membrane protein (intg_mem_TP0381)
CUC06_10560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUC06_10565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CUC06_10575	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CUC06_10580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUC06_10580	COG0574	Belongs to the PEP-utilizing enzyme family
CUC06_10600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CUC06_10610	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CUC06_10610	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CUC06_10645	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CUC06_10650	COG2818	Glycosylase
CUC06_10670	COG3033	Beta-eliminating lyase
CUC06_10685	COG0072	phenylalanine-tRNA ligase activity
CUC06_10685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC06_10710	COG0326	Molecular chaperone. Has ATPase activity
CUC06_10735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CUC06_10740	COG1959	2 iron, 2 sulfur cluster binding
CUC06_10755	COG0352	thiamine-phosphate diphosphorylase activity
CUC06_10760	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CUC06_10775	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_10785	COG1703	isobutyryl-CoA mutase activity
CUC06_10805	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CUC06_10815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC06_10820	COG0418	dihydroorotase activity
CUC06_10835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC06_10855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUC06_10870	COG0534	Mate efflux family protein
CUC06_10875	COG0489	protein tyrosine kinase activity
CUC06_10890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC06_10905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC06_10915	COG1538	Outer membrane efflux protein
CUC06_10935	COG4112	unkown
CUC06_10955	COG0038	chloride channel
CUC06_10970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC06_10980	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC06_10985	COG0586	Pfam SNARE associated Golgi protein
CUC06_11050	COG1518	maintenance of DNA repeat elements
CUC06_11085	COG1012	belongs to the aldehyde dehydrogenase family
CUC06_11115	COG0753	catalase activity
CUC06_11130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CUC06_11135	COG1592	Rubrerythrin
CUC06_11140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CUC06_11175	COG0489	protein tyrosine kinase activity
CUC06_11185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CUC06_11195	COG2244	polysaccharide biosynthetic process
CUC06_11200	COG1215	transferase activity, transferring glycosyl groups
CUC06_11210	COG1216	Glycosyl transferase, family 2
CUC06_11225	COG0438	transferase activity, transferring glycosyl groups
CUC06_11255	COG1216	Glycosyl transferase, family 2
CUC06_11305	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CUC06_11310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC06_11315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CUC06_11320	COG0280	phosphate acetyltransferase
CUC06_11320	COG0281	malic enzyme
CUC06_11335	COG1472	Belongs to the glycosyl hydrolase 3 family
CUC06_11355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUC06_11390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CUC06_11395	COG1063	alcohol dehydrogenase
CUC06_11410	COG0714	Associated with various cellular activities
CUC06_11420	COG0193	aminoacyl-tRNA hydrolase activity
CUC06_11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CUC06_11440	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CUC06_11465	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CUC06_11480	COG0375	protein maturation
CUC06_11510	COG0778	Nitroreductase
CUC06_11515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CUC06_11550	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CUC06_11550	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CUC06_11570	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CUC06_11590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CUC06_11595	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUC06_11640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUC06_11645	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUC06_11660	COG0318	PFAM AMP-dependent synthetase and ligase
CUC06_11695	COG0339	signal peptide processing
CUC06_11705	COG0018	arginyl-trna synthetase
CUC06_11740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CUC06_11745	COG0653	protein targeting
CUC06_11760	COG0494	nUDIX hydrolase
CUC06_11765	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CUC06_11770	COG1131	(ABC) transporter
CUC06_11790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CUC06_11795	COG0564	pseudouridine synthase activity
CUC06_11810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CUC06_11815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUC06_11825	COG0513	Belongs to the DEAD box helicase family
CUC06_11840	COG0673	inositol 2-dehydrogenase activity
CUC06_11855	COG2814	Major facilitator Superfamily
CUC06_11875	COG1971	Probably functions as a manganese efflux pump
CUC06_11905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC06_11930	COG0442	prolyl-tRNA aminoacylation
CUC06_11945	COG2963	transposase activity
CUC06_11980	COG0531	amino acid
CUC06_11985	COG2066	Belongs to the glutaminase family
CUC06_12000	COG1115	amino acid carrier protein
CUC06_12010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CUC06_12015	COG2890	protein-(glutamine-N5) methyltransferase activity
CUC06_12020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUC06_12025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CUC06_12045	COG2226	methyltransferase
CUC06_12050	COG0534	Mate efflux family protein