locus-tag	class	description
CUB96_00065	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CUB96_00095	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CUB96_00100	ENOG4105CI3	gtp-binding protein typa
CUB96_00105	ENOG4107RCW	fructose-bisphosphate aldolase
CUB96_00110	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CUB96_00115	ENOG4105DSF	transport protein
CUB96_00125	ENOG4107RY6	amino acid
CUB96_00130	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CUB96_00140	ENOG4105DI5	UPF0365 protein
CUB96_00145	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CUB96_00155	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CUB96_00165	ENOG4105CDY	transcriptional regulatory protein
CUB96_00170	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CUB96_00175	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CUB96_00200	ENOG4107STF	Involved in phosphonate degradation (By similarity)
CUB96_00210	ENOG4105HMI	Membrane
CUB96_00215	ENOG4105DUM	transcriptional regulator, lysR family
CUB96_00265	ENOG4105K63	Thioredoxin
CUB96_00275	ENOG4105C5S	asparaginyl-tRNA synthetase
CUB96_00300	ENOG4105KVH	Transcriptional regulator
CUB96_00310	ENOG4105UYK	outer membrane protein a
CUB96_00315	ENOG4105DFU	Cell wall formation (By similarity)
CUB96_00325	ENOG4108IUZ	ABC transporter
CUB96_00340	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CUB96_00350	ENOG4105CE9	30S ribosomal protein S2
CUB96_00355	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CUB96_00365	ENOG4108JQ7	(ABC) transporter
CUB96_00380	ENOG4105D49	3-dehydroquinate synthase
CUB96_00390	ENOG4105C0H	protease
CUB96_00400	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CUB96_00405	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CUB96_00410	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CUB96_00415	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
CUB96_00420	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CUB96_00430	ENOG4105CPF	Cell wall formation (By similarity)
CUB96_00435	ENOG4105DFU	Cell wall formation (By similarity)
CUB96_00440	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CUB96_00445	ENOG4105CNI	cell division protein FtsW
CUB96_00455	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CUB96_00460	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CUB96_00465	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CUB96_00470	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CUB96_00475	ENOG4105CJN	penicillin-binding protein
CUB96_00490	ENOG4108V6E	Cell division protein mraZ
CUB96_00495	ENOG4105CY0	Metallo-Beta-Lactamase
CUB96_00500	ENOG4105EN6	Membrane
CUB96_00510	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CUB96_00515	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CUB96_00525	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CUB96_00545	ENOG4107TAE	Glycosyl transferase (Group 1
CUB96_00570	ENOG4105K64	Glycosyl transferase, family 2
CUB96_00575	ENOG4105K64	Glycosyl transferase, family 2
CUB96_00585	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CUB96_00590	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CUB96_00595	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CUB96_00635	ENOG4105W5A	BNR Asp-box repeat protein
CUB96_00655	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
CUB96_00665	ENOG41080P2	Phosphatase
CUB96_00685	ENOG4107QRG	dna polymerase iii
CUB96_00690	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CUB96_00705	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CUB96_00710	ENOG4105CGK	Exodeoxyribonuclease III
CUB96_00745	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CUB96_00755	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CUB96_00765	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CUB96_00775	ENOG4105CAT	Cytidine monophosphate kinase
CUB96_00785	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CUB96_00800	ENOG4105D9P	serine threonine protein kinase
CUB96_00805	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CUB96_00810	ENOG4108Z03	MAF-like protein
CUB96_00815	ENOG4105C7B	Threonine dehydratase
CUB96_00835	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
CUB96_00840	ENOG4105DGA	Diaminopimelate dehydrogenase
CUB96_00870	ENOG4107RAN	Peptidase, M16
CUB96_00875	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CUB96_00900	ENOG4105DXN	mazG family
CUB96_00910	ENOG41081UC	Inherit from COG: Competence protein
CUB96_00930	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CUB96_00945	ENOG4105CP7	Triose-phosphate isomerase
CUB96_00960	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CUB96_00965	ENOG41061MV	Arylsulfatase
CUB96_00970	ENOG4105CDH	Citrulline--aspartate ligase
CUB96_00985	ENOG41082R9	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CUB96_00995	ENOG4105C37	(CBS) domain
CUB96_01005	ENOG41080R2	UPF0102 protein
CUB96_01015	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CUB96_01040	ENOG4105CSM	endonuclease III
CUB96_01055	ENOG4109015	Biopolymer transport protein exbD tolR
CUB96_01080	ENOG4105C03	ribonuclease
CUB96_01100	ENOG4105CN9	Peptidase m42 family protein
CUB96_01115	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
CUB96_01120	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CUB96_01130	ENOG4107QPR	SAICAR synthetase
CUB96_01135	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CUB96_01140	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CUB96_01150	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CUB96_01155	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CUB96_01160	ENOG4105D7W	serine acetyltransferase
CUB96_01180	ENOG4105C2X	Arabinose 5-phosphate isomerase
CUB96_01185	ENOG4105D06	uba thif-type nad fad binding protein
CUB96_01230	ENOG4105CJN	penicillin-binding protein
CUB96_01240	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CUB96_01255	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CUB96_01260	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CUB96_01265	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CUB96_01270	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CUB96_01275	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CUB96_01295	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
CUB96_01340	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CUB96_01345	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CUB96_01360	ENOG4105JRK	feS assembly protein SufD
CUB96_01365	ENOG4105DIW	FeS assembly protein SUFB
CUB96_01375	ENOG4105C3K	feS assembly ATPase SufC
CUB96_01380	ENOG4105G5W	regulator Fur family
CUB96_01385	ENOG4105K46	50S ribosomal protein l27
CUB96_01390	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CUB96_01395	ENOG4105K8N	protein family UPF0079, ATPase
CUB96_01400	ENOG4107XM9	(LipO)protein
CUB96_01410	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
CUB96_01425	ENOG4105CSR	polyphosphate kinase 2
CUB96_01440	ENOG4106H78	methyltransferase
CUB96_01460	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CUB96_01470	ENOG4107QI6	Cysteine desulfurase
CUB96_01475	ENOG4105C3J	Cysteine desulfurase
CUB96_01485	ENOG4107EDW	L-fucose operon activator
CUB96_01490	ENOG4105CSR	polyphosphate kinase 2
CUB96_01510	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CUB96_01530	ENOG4105EMN	RNA polymerase sigma factor
CUB96_01535	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CUB96_01540	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CUB96_01545	ENOG4105NQG	DoxX
CUB96_01570	ENOG41061MV	Arylsulfatase
CUB96_01585	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CUB96_01595	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CUB96_01600	ENOG4105C3G	gtp-binding protein
CUB96_01605	ENOG4105DZ1	carboxypeptidase
CUB96_01610	ENOG4105C79	DNA protecting protein DprA
CUB96_01625	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CUB96_01630	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CUB96_01635	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CUB96_01640	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CUB96_01665	ENOG4108W0I	acetyltransferase
CUB96_01675	ENOG4105CEV	competence damage-inducible protein
CUB96_01690	ENOG4105CDU	Replicative dna helicase
CUB96_01695	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CUB96_01700	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CUB96_01705	ENOG410803B	Involved in the transcription termination process (By similarity)
CUB96_01715	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CUB96_01720	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CUB96_01725	ENOG4105CX6	glutaminyL-tRNA synthetase
CUB96_01740	ENOG4105C54	Major Facilitator superfamily
CUB96_01755	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CUB96_01760	ENOG4108775	30S ribosomal protein S21
CUB96_01770	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CUB96_01775	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CUB96_01780	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CUB96_01815	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CUB96_01825	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CUB96_01830	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CUB96_01850	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CUB96_01855	ENOG4105E2D	ec 3.2.1.52
CUB96_01870	ENOG4106855	Competence protein
CUB96_01890	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CUB96_01895	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CUB96_01920	ENOG4108UW5	maltose o-acetyltransferase
CUB96_01925	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CUB96_01930	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CUB96_01940	ENOG4105C37	(CBS) domain
CUB96_01945	ENOG4105C37	(CBS) domain
CUB96_01970	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CUB96_01975	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CUB96_01980	ENOG4105C0B	DNA polymerase III (alpha subunit)
CUB96_01985	ENOG4105C0B	DNA polymerase III (alpha subunit)
CUB96_01995	ENOG4105CVK	Glutamate decarboxylase
CUB96_02010	ENOG4105E2D	ec 3.2.1.52
CUB96_02045	ENOG4107FW0	short-chain dehydrogenase reductase
CUB96_02055	ENOG4108IJ6	ABC transporter
CUB96_02075	ENOG4107T0D	ABC, transporter
CUB96_02115	ENOG4108IPT	Naphthoate synthase
CUB96_02135	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CUB96_02140	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CUB96_02145	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CUB96_02155	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CUB96_02170	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CUB96_02215	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CUB96_02285	ENOG4105C3U	ABC transporter
CUB96_02295	ENOG4108M8S	permease YjgP YjgQ family protein
CUB96_02310	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CUB96_02325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CUB96_02330	ENOG4105BZU	Histidine kinase
CUB96_02340	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CUB96_02345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CUB96_02350	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CUB96_02355	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CUB96_02360	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CUB96_02365	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CUB96_02370	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CUB96_02375	ENOG4108542	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CUB96_02380	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CUB96_02385	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CUB96_02395	ENOG41080P9	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CUB96_02400	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CUB96_02405	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CUB96_02410	ENOG41082SA	50s ribosomal protein l29
CUB96_02415	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CUB96_02420	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CUB96_02440	ENOG4105CNT	hydrolase family 2
CUB96_02495	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CUB96_02500	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CUB96_02505	ENOG4105K6T	rare lipoprotein A
CUB96_02515	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CUB96_02520	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CUB96_02525	ENOG4105VIE	preprotein translocase, subunit YajC
CUB96_02550	ENOG4105K5M	30s ribosomal protein S16
CUB96_02555	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CUB96_02560	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CUB96_02580	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CUB96_02590	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
CUB96_02615	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CUB96_02655	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CUB96_02660	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CUB96_02665	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUB96_02670	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CUB96_02720	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CUB96_02730	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CUB96_02735	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CUB96_02745	ENOG4105FE9	pseudouridine synthase
CUB96_02765	ENOG4105CY0	Metallo-Beta-Lactamase
CUB96_02770	ENOG41080E8	Transcriptional regulator, Spx MgsR family
CUB96_02775	ENOG4105EYW	Ion transport protein
CUB96_02785	ENOG4105CPQ	Dehydrogenase
CUB96_02790	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CUB96_02800	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
CUB96_02875	ENOG4105C8P	)-transporter
CUB96_02885	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CUB96_02890	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CUB96_02910	ENOG4105C7K	acetolactate synthase
CUB96_02915	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CUB96_02925	ENOG4105CTQ	phosphohexokinase
CUB96_02930	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CUB96_02935	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CUB96_02945	ENOG4105CYC	Transferase
CUB96_02950	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CUB96_02955	ENOG4105D9Q	decarboxylase (Beta subunit)
CUB96_02960	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CUB96_02970	ENOG4107QX3	carboxylase
CUB96_02975	ENOG4108ZVT	methylmalonyl-coA epimerase
CUB96_02985	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CUB96_02995	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
CUB96_03005	ENOG4105C9B	Cysteine desulfurase
CUB96_03020	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CUB96_03025	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CUB96_03035	ENOG4107VAM	peptidase, m28
CUB96_03055	ENOG4105D60	lipoprotein releasing system transmembrane protein
CUB96_03065	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CUB96_03070	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CUB96_03080	ENOG4108JQC	penicillin-binding protein 1A
CUB96_03110	ENOG4107RJ1	sodium solute
CUB96_03135	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CUB96_03140	ENOG4105CZX	twitching motility protein
CUB96_03145	ENOG4105CZX	twitching motility protein
CUB96_03165	ENOG4107PE3	Mammalian cell entry related domain protein
CUB96_03170	ENOG4105DHJ	ABC, transporter
CUB96_03185	ENOG4105BZ1	(ABC) transporter
CUB96_03190	ENOG4105BZ1	(ABC) transporter
CUB96_03205	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CUB96_03250	ENOG4107QSI	ABC, transporter
CUB96_03255	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CUB96_03260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CUB96_03280	ENOG4105DHU	Bile acid
CUB96_03315	ENOG4105FA0	parb-like partition protein
CUB96_03380	ENOG4105CE1	Ferrous iron transport protein b
CUB96_03390	ENOG41061MV	Arylsulfatase
CUB96_03400	ENOG4105DZP	Membrane-associated zinc metalloprotease
CUB96_03410	ENOG4105DWY	Agmatine deiminase
CUB96_03415	ENOG4105DZ0	fad dependent oxidoreductase
CUB96_03435	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CUB96_03440	ENOG4105CXT	aspartate transcarbamylase
CUB96_03445	ENOG4105CD3	dihydroorotase
CUB96_03450	ENOG4108R96	Methyltransferase, YaeB family
CUB96_03460	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CUB96_03480	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CUB96_03485	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CUB96_03490	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CUB96_03495	ENOG4105CW7	secretion protein, HlyD family
CUB96_03500	ENOG4105M6F	mutator MutT protein
CUB96_03510	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CUB96_03515	ENOG4105DKQ	ROK family
CUB96_03520	ENOG4105SCY	DNAK suppressor
CUB96_03525	ENOG41083ND	50S ribosomal protein L33
CUB96_03530	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CUB96_03535	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
CUB96_03545	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CUB96_03550	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CUB96_03560	ENOG4105K78	MarR family Transcriptional regulator
CUB96_03575	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CUB96_03615	ENOG4107WDG	serine threonine protein kinase
CUB96_03620	ENOG4107QJE	Chromosome Partitioning Protein
CUB96_03635	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CUB96_03650	ENOG4105E09	nadh pyrophosphatase
CUB96_03655	ENOG4105D7K	pfkb domain protein
CUB96_03670	ENOG4105CUZ	uba thif-type nad fad binding protein
CUB96_03680	ENOG4105D48	metallophosphoesterase
CUB96_03690	ENOG4105C31	Tryptophanyl-tRNA synthetase
CUB96_03700	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CUB96_03715	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CUB96_03720	ENOG4105ERH	Fumarylacetoacetate hydrolase
CUB96_03755	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CUB96_03760	ENOG41066A3	ATP guanido phosphotransferase
CUB96_03765	ENOG4108Z0C	Uvrb UvrC protein
CUB96_03775	ENOG4105DIK	(ABC) transporter
CUB96_03795	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
CUB96_03810	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CUB96_03815	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CUB96_03820	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CUB96_03825	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CUB96_03835	ENOG4107QJQ	Mate efflux family protein
CUB96_03840	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CUB96_03860	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CUB96_03870	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CUB96_03875	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CUB96_03885	ENOG4105BZG	amino acid carrier protein
CUB96_03900	ENOG4105CSV	Glutaminase
CUB96_03905	ENOG4105E5D	amino acid
CUB96_03930	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CUB96_03955	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CUB96_03985	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
CUB96_04000	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CUB96_04020	ENOG4105EPC	oxidoreductase
CUB96_04035	ENOG4105C1J	atp-dependent rna helicase
CUB96_04045	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CUB96_04050	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CUB96_04070	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
CUB96_04090	ENOG4105CJ1	ABC, transporter
CUB96_04095	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CUB96_04100	ENOG4108YZ4	nudix hydrolase
CUB96_04115	ENOG4107QZM	n-acetylglutamate synthase
CUB96_04120	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CUB96_04165	ENOG4105C75	arginyL-tRNA synthetase
CUB96_04175	ENOG4105DGW	oligopeptidase A
CUB96_04210	ENOG4105CEY	Amp-dependent synthetase and ligase
CUB96_04225	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CUB96_04230	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CUB96_04265	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CUB96_04275	ENOG4105E2D	ec 3.2.1.52
CUB96_04295	ENOG4107GFK	fumarate
CUB96_04305	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CUB96_04320	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CUB96_04325	ENOG4108RCM	Nitroreductase
CUB96_04350	ENOG4108USZ	hydrogenase
CUB96_04360	ENOG4105DPX	Hydrogenase, large subunit
CUB96_04365	ENOG4105E3S	small subunit
CUB96_04385	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CUB96_04400	ENOG4105BZ4	penicillin-binding protein
CUB96_04405	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CUB96_04415	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CUB96_04425	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CUB96_04440	ENOG4105CPQ	Dehydrogenase
CUB96_04445	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CUB96_04455	ENOG4105CSA	Coproporphyrinogen iii oxidase
CUB96_04470	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CUB96_04475	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CUB96_04490	ENOG4105C6K	Malic enzyme
CUB96_04505	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CUB96_04510	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CUB96_04515	ENOG4105C87	Aminotransferase class I and II
CUB96_04540	ENOG4105EXC	Acyl-transferase
CUB96_04565	ENOG4105K64	Glycosyl transferase, family 2
CUB96_04575	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
CUB96_04585	ENOG4107XU6	Glycosyl transferase (Group 1
CUB96_04615	ENOG4105E2K	Glycosyl transferase (Group 1
CUB96_04625	ENOG4107XU6	Glycosyl transferase (Group 1
CUB96_04635	ENOG4105D3Q	Sugar transferase
CUB96_04645	ENOG4108QV3	biosynthesis protein
CUB96_04655	ENOG4105CNU	cell division protein FtsK
CUB96_04665	ENOG41068WN	
CUB96_04675	ENOG4108RAC	Rubrerythrin
CUB96_04680	ENOG4105CRE	cytochrome C
CUB96_04695	ENOG4105CH6	catalase
CUB96_04715	ENOG4105C26	Dehydrogenase
CUB96_04795	ENOG4107T5V	SNARE associated Golgi
CUB96_04800	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CUB96_04805	ENOG4105D82	Glutamate dehydrogenase
CUB96_04850	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CUB96_04860	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CUB96_04865	ENOG4105DGW	oligopeptidase A
CUB96_04870	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CUB96_04890	ENOG4107QI1	Mate efflux family protein
CUB96_04905	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CUB96_04910	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CUB96_04915	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CUB96_04925	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CUB96_04945	ENOG4105C5X	domain protein
CUB96_04950	ENOG4105C1J	atp-dependent rna helicase
CUB96_04955	ENOG41081ID	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CUB96_04975	ENOG4105DJT	lAO AO transport system ATPase
CUB96_04980	ENOG4105E2D	ec 3.2.1.52
CUB96_04985	ENOG4105E2D	ec 3.2.1.52
CUB96_05005	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CUB96_05020	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CUB96_05025	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CUB96_05045	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
CUB96_05070	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CUB96_05100	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CUB96_05105	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CUB96_05110	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CUB96_05115	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CUB96_05130	ENOG4105C0F	tryptophanase EC 4.1.99.1
CUB96_05150	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CUB96_05185	ENOG4105D5P	Methylmalonyl-coA mutase
CUB96_05205	ENOG4105DR4	Methyltransferase
CUB96_05215	ENOG4107QP8	phosphohexose isomerase
CUB96_05225	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CUB96_05230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CUB96_05235	ENOG4105CEN	a g-specific adenine glycosylase
CUB96_05240	ENOG4105E2X	shikimate dehydrogenase
CUB96_05295	ENOG4107XM3	UPF0442 protein
CUB96_05300	ENOG4105DWK	Membrane
CUB96_05340	ENOG4108Z66	YbaK ebsC protein
CUB96_05345	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CUB96_05410	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CUB96_05415	ENOG4105C83	adenylosuccinate lyase
CUB96_05435	ENOG4105C2M	dna polymerase I
CUB96_05470	ENOG4105DHS	permease protein
CUB96_05475	ENOG4105CM4	permease protein
CUB96_05480	ENOG4108IPW	abc transporter atp-binding protein
CUB96_05495	ENOG4105CRE	cytochrome C
CUB96_05510	ENOG4105E2D	ec 3.2.1.52
CUB96_05525	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CUB96_05540	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CUB96_05555	ENOG4105WMR	Protein CrcB homolog
CUB96_05570	ENOG4105DZR	Type I site-specific deoxyribonuclease
CUB96_05580	ENOG4108JB8	alcohol dehydrogenase
CUB96_05605	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CUB96_05610	ENOG4105DVP	Adenine-specific
CUB96_05630	ENOG4105DIN	metallophosphoesterase
CUB96_05640	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CUB96_05650	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CUB96_05660	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CUB96_05670	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CUB96_05690	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CUB96_05695	ENOG410845M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes (By similarity)
CUB96_05700	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CUB96_05705	ENOG4105D64	Mechanosensitive ion channel
CUB96_05715	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CUB96_05720	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CUB96_05725	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CUB96_05735	ENOG4105CY0	Metallo-Beta-Lactamase
CUB96_05755	ENOG4108HMX	isocitrate dehydrogenase (NADP)
CUB96_05760	ENOG4105MEV	Acyl-transferase
CUB96_05775	ENOG4105NQN	cytochrome C
CUB96_05785	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CUB96_05820	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CUB96_05845	ENOG4107QNG	Phosphoribosylglycinamide synthetase
CUB96_05850	ENOG4108XC3	NADH ubiquinone oxidoreductase
CUB96_05855	ENOG4105CKU	formyltetrahydrofolate synthetase
CUB96_05860	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CUB96_05885	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CUB96_05895	ENOG4108J59	Extracellular solute-binding protein, family 5
CUB96_05905	ENOG4108JQ7	(ABC) transporter
CUB96_05910	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CUB96_05925	ENOG4105EMK	carboxylate amino acid amine transporter
CUB96_05955	ENOG4105C0H	protease
CUB96_05975	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CUB96_06015	ENOG4105EDR	glucose galactose transporter
CUB96_06025	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
CUB96_06035	ENOG4105CMG	Carbohydrate kinase
CUB96_06085	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CUB96_06090	ENOG4105DR4	Methyltransferase
CUB96_06100	ENOG4105VB6	UPF0109 protein
CUB96_06115	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
CUB96_06125	ENOG4105E2D	ec 3.2.1.52
CUB96_06135	ENOG4105C3S	Mate efflux family protein
CUB96_06155	ENOG4105VUF	Transcriptional regulator
CUB96_06160	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
CUB96_06170	ENOG4105CPC	Aldo Keto reductase
CUB96_06190	ENOG4105DIN	metallophosphoesterase
CUB96_06195	ENOG4107SET	aldo keto reductase
CUB96_06200	ENOG4105ENX	hydrolase
CUB96_06205	ENOG4105CV8	reductase
CUB96_06215	ENOG4105C87	Aminotransferase class I and II
CUB96_06245	ENOG4105EXC	Acyl-transferase
CUB96_06260	ENOG4105C0H	protease
CUB96_06265	ENOG4105C0H	protease
CUB96_06305	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
CUB96_06310	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CUB96_06315	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CUB96_06350	ENOG4105CV8	reductase
CUB96_06355	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
CUB96_06370	ENOG4105CHM	Aminotransferase
CUB96_06375	ENOG4108ZB6	transcriptional regulator AsnC family
CUB96_06385	ENOG4105NWN	ApaG protein
CUB96_06410	ENOG4105DFA	alanine racemase domain protein
CUB96_06425	ENOG4105DA5	(ABC) transporter
CUB96_06430	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CUB96_06435	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CUB96_06440	ENOG41080Z8	PHOSPHOCARRIER protein
CUB96_06445	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CUB96_06450	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CUB96_06455	ENOG4105DBV	ornithine carbamoyltransferase
CUB96_06460	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CUB96_06470	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CUB96_06475	ENOG4105KPE	licD family
CUB96_06495	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
CUB96_06500	ENOG4105KPE	licD family
CUB96_06540	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CUB96_06555	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CUB96_06560	ENOG4105C22	threonyL-tRNA synthetase
CUB96_06575	ENOG4105D52	delta-aminolevulinic acid dehydratase
CUB96_06585	ENOG4105ETX	regulatoR
CUB96_06595	ENOG41065SU	Two-component system sensor kinase
CUB96_06600	ENOG4108IAJ	Nad-dependent epimerase dehydratase
CUB96_06635	ENOG4105CEY	Amp-dependent synthetase and ligase
CUB96_06640	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CUB96_06670	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
CUB96_06675	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CUB96_06680	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CUB96_06695	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CUB96_06730	ENOG4108UB4	uncharacterized protein ygjQ
CUB96_06755	ENOG410834F	Transcriptional regulator
CUB96_06775	ENOG4107WAU	Protein tyrosine phosphatase
CUB96_06785	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CUB96_06790	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CUB96_06815	ENOG4107QN2	dihydrolipoyl dehydrogenase
CUB96_06820	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CUB96_06840	ENOG4107ENK	receptor
CUB96_06855	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
CUB96_06860	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CUB96_06875	ENOG4108YZT	Adenosylcobinamide kinase
CUB96_06910	ENOG4105CTQ	phosphohexokinase
CUB96_06930	ENOG4105E2D	ec 3.2.1.52
CUB96_06935	ENOG4105D1H	recombination factor protein RarA
CUB96_06940	ENOG4105CNT	hydrolase family 2
CUB96_06945	ENOG4105CNT	hydrolase family 2
CUB96_07000	ENOG4105ENH	Sulfatase
CUB96_07015	ENOG4105DJ4	phosphatidylserine decarboxylase
CUB96_07025	ENOG4105C7K	acetolactate synthase
CUB96_07030	ENOG4107VXZ	Hydrolase
CUB96_07035	ENOG410872P	Binds directly to 16S ribosomal RNA (By similarity)
CUB96_07045	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CUB96_07050	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CUB96_07070	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CUB96_07085	ENOG4105GVR	general secretion pathway protein D
CUB96_07115	ENOG4105CQ7	ATP-dependent helicase
CUB96_07130	ENOG4105CN1	protease
CUB96_07135	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CUB96_07150	ENOG4108UQS	dipeptidase
CUB96_07155	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CUB96_07160	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CUB96_07165	ENOG4105F7J	membrane-bound serine protease
CUB96_07170	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CUB96_07185	ENOG4107S1W	4-alpha-glucanotransferase
CUB96_07200	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CUB96_07210	ENOG4108R6K	riboflavin synthase, subunit alpha
CUB96_07225	ENOG4107BJW	polysaccharide deacetylase
CUB96_07240	ENOG4105GKE	subunit e
CUB96_07250	ENOG4108IEH	NADH dehydrogenase subunit g
CUB96_07255	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
CUB96_07265	ENOG4107UFS	subunit j
CUB96_07270	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CUB96_07285	ENOG4105C8S	subunit m
CUB96_07290	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CUB96_07320	ENOG4105EAH	synthase
CUB96_07325	ENOG4105C8M	UPF0272 protein
CUB96_07330	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CUB96_07335	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
CUB96_07340	ENOG4105F32	YngK protein
CUB96_07355	ENOG4105CJR	Integral membrane protein (MviN
CUB96_07370	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CUB96_07375	ENOG4107QHF	type ii secretion system protein e
CUB96_07380	ENOG4107QHF	type ii secretion system protein e
CUB96_07385	ENOG4105D7Q	type ii secretion system
CUB96_07395	ENOG4105CKK	Glycosyl transferase, family 2
CUB96_07405	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CUB96_07415	ENOG4108R99	pseudouridine synthase
CUB96_07425	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CUB96_07440	ENOG4105BZN	citrate synthase
CUB96_07465	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CUB96_07475	ENOG4107QW4	alcohol dehydrogenase
CUB96_07480	ENOG4107S85	alpha-2-macroglobulin domain protein
CUB96_07490	ENOG4108HED	Type II restriction
CUB96_07495	ENOG410631K	Membrane
CUB96_07510	ENOG4107QKA	exodeoxyribonuclease V beta
CUB96_07525	ENOG4105DZP	Membrane-associated zinc metalloprotease
CUB96_07530	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CUB96_07535	ENOG4105VJV	50s ribosomal protein L35
CUB96_07540	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CUB96_07560	ENOG4106UW1	Major Facilitator superfamily
CUB96_07565	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CUB96_07575	ENOG4108HCJ	Hydrolase
CUB96_07605	ENOG4105F1A	Pyruvate formate-lyase
CUB96_07615	ENOG4105YK5	50S ribosomal protein L36
CUB96_07620	ENOG4105DWV	Homoserine O-trans-acetylase
CUB96_07640	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CUB96_07655	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CUB96_07665	ENOG4105CRQ	synthase (Component I)
CUB96_07685	ENOG4105CPC	Aldo Keto reductase
CUB96_07720	ENOG4107QMH	DNA methylase
CUB96_07730	ENOG4105C0D	helicase
CUB96_07765	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CUB96_07780	ENOG4107YBY	Hydrolase
CUB96_07790	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CUB96_07795	ENOG4108ZT0	50S ribosomal protein l17
CUB96_07800	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CUB96_07810	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CUB96_07820	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CUB96_07825	ENOG4108ZJ4	polysaccharide deacetylase
CUB96_07835	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CUB96_07860	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CUB96_07875	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CUB96_07890	ENOG4105DSJ	YicC domain protein
CUB96_07895	ENOG4105JKW	Valine--pyruvate aminotransferase
CUB96_07910	ENOG4105MH8	Thioredoxin disulfide isomerase
CUB96_07915	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
CUB96_07925	ENOG4105CTQ	phosphohexokinase
CUB96_07930	ENOG4105DZ1	carboxypeptidase
CUB96_07945	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CUB96_07950	ENOG4107Q5Z	Binds together with S18 to 16S ribosomal RNA (By similarity)
CUB96_07955	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CUB96_07960	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CUB96_07975	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CUB96_07980	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CUB96_08005	ENOG4105CQB	FAD linked oxidase domain protein
CUB96_08020	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
CUB96_08030	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CUB96_08035	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CUB96_08040	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CUB96_08045	ENOG4105VZ9	UPF0235 protein
CUB96_08075	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CUB96_08095	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CUB96_08100	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CUB96_08110	ENOG4105E5Q	amino acid AbC transporter
CUB96_08115	ENOG4105CDA	abc transporter atp-binding protein
CUB96_08135	ENOG4105I08	Pseudouridine synthase
CUB96_08140	ENOG4105C34	Pseudouridine synthase
CUB96_08145	ENOG4108RCM	Nitroreductase
CUB96_08170	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CUB96_08175	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CUB96_08210	ENOG4105NRA	50s ribosomal protein l31 type b
CUB96_08215	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CUB96_08220	ENOG4105C6K	Malic enzyme
CUB96_08225	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
CUB96_08240	ENOG4105DJB	Major Facilitator Superfamily
CUB96_08250	ENOG4108JA2	transcriptioN-repair coupling factor
CUB96_08255	ENOG4108JA2	transcriptioN-repair coupling factor
CUB96_08260	ENOG4105D9P	serine threonine protein kinase
CUB96_08265	ENOG4105CGS	Alpha-glucosidase
CUB96_08280	ENOG4105BZA	Phosphoglycerate kinase
CUB96_08290	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CUB96_08305	ENOG4105D75	Capsular exopolysaccharide family
CUB96_08350	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CUB96_08355	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CUB96_08360	ENOG4105CFG	Acts as a chaperone (By similarity)
CUB96_08365	ENOG4105BZF	Glycosyl transferase (Group 1
CUB96_08390	ENOG4105CQS	hydrogenase expression formation protein HypD
CUB96_08410	ENOG4105CUT	histidyl-tRNA synthetase
CUB96_08415	ENOG4105C9M	aspartyl-trna synthetase
CUB96_08445	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CUB96_08470	ENOG4105CHR	reductase
CUB96_08475	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CUB96_08485	ENOG4105EEI	dihydropteroate synthase
CUB96_08495	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CUB96_08500	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CUB96_08510	ENOG4105CJ1	ABC, transporter
CUB96_08515	ENOG4107QWP	ABC-2 type transporter
CUB96_08520	ENOG4107QWP	ABC-2 type transporter
CUB96_08535	ENOG4105CDU	Replicative dna helicase
CUB96_08765	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CUB96_08770	ENOG4105E0X	reductase
CUB96_08775	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CUB96_08785	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CUB96_08810	ENOG4105C8J	)-transporter
CUB96_08815	ENOG4105D3R	alkyl hydroperoxide reductase
CUB96_08825	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CUB96_08830	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CUB96_08865	ENOG4105C1V	Peptidase, M16
CUB96_08880	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CUB96_08890	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CUB96_08900	ENOG4105C8U	phosphate abc transporter
CUB96_08910	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CUB96_08915	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CUB96_08930	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CUB96_08935	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CUB96_08940	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CUB96_08960	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CUB96_08980	ENOG4105E6M	Sulphatase-modifying factor protein
CUB96_08995	ENOG4105CFP	Peptidase U32
CUB96_09005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CUB96_09010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CUB96_09025	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CUB96_09035	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CUB96_09045	ENOG4105DIN	metallophosphoesterase
CUB96_09050	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CUB96_09100	ENOG4105C3M	thioredoxin reductase
CUB96_09105	ENOG4105EJQ	L-serine dehydratase
CUB96_09120	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CUB96_09135	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CUB96_09140	ENOG4105DSB	aldose 1-epimerase
CUB96_09175	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CUB96_09180	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CUB96_09190	ENOG4105CBC	glutamate synthase
CUB96_09205	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CUB96_09210	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CUB96_09215	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
CUB96_09220	ENOG4105C30	Nad-dependent epimerase dehydratase
CUB96_09225	ENOG4105DFD	Na H antiporter
CUB96_09235	ENOG4105DG6	mannose-6-phosphate isomerase
CUB96_09245	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CUB96_09255	ENOG4108JQC	penicillin-binding protein 1A
CUB96_09265	ENOG4109015	Biopolymer transport protein exbD tolR
CUB96_09275	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CUB96_09280	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CUB96_09285	ENOG4108UJD	30S ribosomal protein S9
CUB96_09290	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CUB96_09295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CUB96_09300	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CUB96_09305	ENOG4105W5Q	DNA repair protein (RadC
CUB96_09325	ENOG4105C6E	dna polymerase iii
CUB96_09330	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CUB96_09350	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
CUB96_09410	ENOG4105D49	3-dehydroquinate synthase
CUB96_09430	ENOG4107SFQ	iron-sulfur binding
CUB96_09445	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
CUB96_09450	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
CUB96_09460	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CUB96_09465	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CUB96_09470	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CUB96_09475	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CUB96_09485	ENOG4105CAS	nag kinase
CUB96_09510	ENOG4108JJB	ABC transporter
CUB96_09515	ENOG4105DVT	helicase
CUB96_09525	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CUB96_09530	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
CUB96_09540	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
CUB96_09545	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CUB96_09560	ENOG41085AM	50S ribosomal protein L28
CUB96_09575	ENOG4105CJ2	(LipO)protein
CUB96_09580	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
CUB96_09585	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CUB96_09595	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
CUB96_09605	ENOG4105C6F	GntR Family Transcriptional Regulator
CUB96_09610	ENOG4105DKW	ABC transporter
CUB96_09615	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CUB96_09630	ENOG4105ECP	epimerase
CUB96_09660	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CUB96_09710	ENOG4105V75	Transcriptional regulator
CUB96_09715	ENOG4105CPC	Aldo Keto reductase
CUB96_09730	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CUB96_09750	ENOG4105C08	Histidine kinase
CUB96_09755	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CUB96_09760	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CUB96_09800	ENOG4105CNA	YD repeat protein
CUB96_09865	ENOG4107QI1	Mate efflux family protein
CUB96_09890	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CUB96_09895	ENOG4105CMR	udp-glucose 4-epimerase
CUB96_09930	ENOG4105E0M	Sulfatase
CUB96_09955	ENOG4105C01	Dihydroxy-acid dehydratase
CUB96_09960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CUB96_09985	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CUB96_09990	ENOG4107RAQ	aminopeptidase
CUB96_10005	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CUB96_10035	ENOG4105GVR	general secretion pathway protein D
CUB96_10040	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CUB96_10045	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CUB96_10050	ENOG4105C59	p-type ATPase
CUB96_10060	ENOG4105DKQ	ROK family
CUB96_10065	ENOG4108Z6B	deaminase
CUB96_10070	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CUB96_10075	ENOG4105CA0	peroxidase
CUB96_10090	ENOG4105CE1	Ferrous iron transport protein b
CUB96_10135	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CUB96_10140	ENOG4108IYU	L-aspartate oxidase
CUB96_10150	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
CUB96_10160	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CUB96_10165	ENOG4105CBG	Sulfatase
CUB96_10195	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CUB96_10200	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CUB96_10205	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CUB96_10250	ENOG4108IJF	Heavy metal efflux pump, CzcA
CUB96_10270	ENOG4105SYT	Methylenetetrahydrofolate reductase
CUB96_10280	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUB96_10285	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CUB96_10290	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CUB96_10300	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CUB96_10310	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CUB96_10325	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CUB96_10330	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CUB96_10335	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CUB96_10340	ENOG4107Z3D	50S ribosomal protein l10
CUB96_10345	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CUB96_10350	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CUB96_10355	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CUB96_10370	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CUB96_10380	ENOG4105CBG	Sulfatase
CUB96_10385	ENOG4105E2D	ec 3.2.1.52
CUB96_10390	ENOG4105C8N	cysteinyl-tRNA synthetase
CUB96_10400	ENOG410631K	Membrane
CUB96_10410	ENOG4105C5H	ABC transporter
CUB96_10455	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CUB96_10460	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CUB96_10525	ENOG4105ENX	hydrolase
CUB96_10535	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CUB96_10555	ENOG4105MS2	ribosomal subunit Interface protein
CUB96_10630	ENOG4105E33	succinate dehydrogenase
CUB96_10660	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CUB96_10675	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CUB96_10680	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CUB96_10685	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
CUB96_10690	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CUB96_10710	ENOG4105D3Q	Sugar transferase
CUB96_10715	ENOG4105VFU	Rna-binding protein
CUB96_10735	ENOG4105IDI	abc transporter atp-binding protein
CUB96_10760	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CUB96_10765	ENOG4105CGK	Exodeoxyribonuclease III
CUB96_10770	ENOG4105CHV	Transcription elongation factor NusA
CUB96_10775	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CUB96_10780	ENOG41084NN	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CUB96_10785	ENOG4105ENH	Sulfatase
CUB96_10805	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
CUB96_10810	ENOG4105CE4	GlcNAc 6-P deacetylase
CUB96_10815	ENOG4105C7S	Dehydrogenase
CUB96_10820	ENOG4108Z0Z	intracellular protease Pfpi family
CUB96_10825	ENOG4105K64	Glycosyl transferase, family 2
CUB96_10840	ENOG4105K64	Glycosyl transferase, family 2
CUB96_10850	ENOG4105K64	Glycosyl transferase, family 2
CUB96_10870	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CUB96_10885	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CUB96_10890	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CUB96_10895	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CUB96_10900	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CUB96_10905	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CUB96_10910	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CUB96_10915	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CUB96_10920	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CUB96_10930	ENOG41082A0	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CUB96_10935	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CUB96_10940	ENOG4105K6T	rare lipoprotein A
CUB96_10945	ENOG4105CGH	5'-nucleotidase
CUB96_10955	ENOG4105C0D	helicase
CUB96_10960	ENOG410823G	oxidoreductase
CUB96_10975	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CUB96_10980	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CUB96_10985	ENOG4105CFP	Peptidase U32
CUB96_10995	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CUB96_11005	ENOG4108WBT	adenosyltransferase
CUB96_11015	ENOG4105CZM	Major Facilitator
CUB96_11025	ENOG4105E0Y	RtcB Protein
CUB96_11050	ENOG4107QM5	aconitate hydratase
CUB96_11055	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
CUB96_11075	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CUB96_11120	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CUB96_11125	ENOG4108Z6Z	Transcriptional regulator
CUB96_11135	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CUB96_11180	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
CUB96_11185	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CUB96_11190	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CUB96_11195	ENOG4105C59	p-type ATPase
CUB96_11215	ENOG4105C8Y	Acetylornithine aminotransferase
CUB96_11220	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CUB96_11225	ENOG4105G6Z	alkaline phosphatase
CUB96_11230	ENOG4105E2D	ec 3.2.1.52
CUB96_11235	ENOG4105CN9	Peptidase m42 family protein
CUB96_11245	ENOG4108RAC	Rubrerythrin
CUB96_11285	ENOG4105C8P	)-transporter
CUB96_11305	ENOG4105DME	alpha-galactosidase
CUB96_11310	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CUB96_11330	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CUB96_11335	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CUB96_11345	ENOG4105EQI	Metal Dependent Phosphohydrolase
CUB96_11355	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CUB96_11360	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CUB96_11375	ENOG4105CH7	arginosuccinase
CUB96_11380	ENOG4105CHH	sulfate transporter
CUB96_11390	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CUB96_11440	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CUB96_11460	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
CUB96_11465	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CUB96_11470	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
CUB96_11480	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CUB96_11485	ENOG4105C08	Histidine kinase
CUB96_11500	ENOG4105CNT	hydrolase family 2
CUB96_11510	ENOG4105F8V	Hydrolase, tatD family
CUB96_11540	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CUB96_11550	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CUB96_11555	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CUB96_11570	ENOG4105C0H	protease
CUB96_11580	ENOG4108ZP8	Acetolactate synthase small subunit
CUB96_11585	ENOG4105CQ7	ATP-dependent helicase
CUB96_11605	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CUB96_11620	ENOG4105KVH	Transcriptional regulator
CUB96_11630	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CUB96_11640	ENOG4105CRK	lysyL-tRNA synthetase
CUB96_11650	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CUB96_11655	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CUB96_11670	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
CUB96_11690	ENOG4105C0P	Mg chelatase subunit ChlI
CUB96_11705	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CUB96_11715	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
CUB96_11720	ENOG4105GTN	ParB Domain Protein Nuclease
CUB96_11735	ENOG4105KK6	nuclease
CUB96_11745	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
CUB96_11755	ENOG4105NAU	thioesterase Superfamily protein
CUB96_11760	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CUB96_11770	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CUB96_11820	ENOG4107QWE	)-transporter
CUB96_11835	ENOG4105EXC	Acyl-transferase
CUB96_11855	ENOG4105K64	Glycosyl transferase, family 2
CUB96_11860	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CUB96_11880	ENOG4105DIN	metallophosphoesterase
CUB96_11895	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CUB96_11905	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
CUB96_11915	ENOG4105X0D	Fimbrial protein
CUB96_11920	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CUB96_11940	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CUB96_11950	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)