locus-tag	class	description
Amuc_0001	COG0494	nUDIX hydrolase
Amuc_0002	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Amuc_0003	COG1131	(ABC) transporter
Amuc_0007	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Amuc_0008	COG0564	pseudouridine synthase activity
Amuc_0011	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Amuc_0012	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Amuc_0015	COG0513	Belongs to the DEAD box helicase family
Amuc_0017	COG0673	inositol 2-dehydrogenase activity
Amuc_0020	COG2814	Major facilitator Superfamily
Amuc_0021	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Amuc_0024	COG1971	Probably functions as a manganese efflux pump
Amuc_0029	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Amuc_0034	COG0442	prolyl-tRNA aminoacylation
Amuc_0037	COG0531	amino acid
Amuc_0038	COG2066	Belongs to the glutaminase family
Amuc_0040	COG1115	amino acid carrier protein
Amuc_0041	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Amuc_0042	COG2890	protein-(glutamine-N5) methyltransferase activity
Amuc_0043	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Amuc_0044	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Amuc_0047	COG2226	methyltransferase
Amuc_0048	COG0534	Mate efflux family protein
Amuc_0051	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Amuc_0052	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Amuc_0055	COG1121	(ABC) transporter
Amuc_0056	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Amuc_0057	COG3880	PFAM UvrB UvrC protein
Amuc_0058	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Amuc_0059	COG0542	response to heat
Amuc_0064	COG0179	Fumarylacetoacetate (FAA) hydrolase
Amuc_0065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Amuc_0068	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Amuc_0068	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Amuc_0070	COG0180	Tryptophanyl-tRNA synthetase
Amuc_0072	COG1692	metallophosphoesterase
Amuc_0073	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Amuc_0075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Amuc_0076	COG2816	NAD+ diphosphatase activity
Amuc_0077	COG0156	8-amino-7-oxononanoate synthase activity
Amuc_0079	COG1192	Involved in chromosome partitioning
Amuc_0080	COG3266	domain, Protein
Amuc_0080	COG0515	serine threonine protein kinase
Amuc_0086	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Amuc_0089	COG3189	MarR family transcriptional regulator
Amuc_0090	COG0181	hydroxymethylbilane synthase activity
Amuc_0091	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Amuc_0093	COG1469	GTP cyclohydrolase I activity
Amuc_0094	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Amuc_0095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Amuc_0096	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Amuc_0097	COG1940	carbohydrate kinase activity
Amuc_0100	COG0494	nUDIX hydrolase
Amuc_0102	COG1566	PFAM secretion protein HlyD family protein
Amuc_0103	COG1136	(ABC) transporter
Amuc_0103	COG0577	efflux transmembrane transporter activity
Amuc_0104	COG1136	(ABC) transporter
Amuc_0104	COG0577	efflux transmembrane transporter activity
Amuc_0105	COG1538	Outer membrane efflux protein
Amuc_0108	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Amuc_0110	COG1720	tRNA m6t6A37 methyltransferase activity
Amuc_0111	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Amuc_0112	COG0540	Belongs to the ATCase OTCase family
Amuc_0113	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Amuc_0116	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Amuc_0117	COG2957	Belongs to the agmatine deiminase family
Amuc_0119	COG0750	zinc metalloprotease
Amuc_0121	COG3119	arylsulfatase activity
Amuc_0133	COG1475	DNA binding
Amuc_0140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Amuc_0143	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Amuc_0144	COG0601	transmembrane transport
Amuc_0155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Amuc_0156	COG1132	(ABC) transporter
Amuc_0157	COG1132	(ABC) transporter
Amuc_0160	COG1127	ABC transporter
Amuc_0161	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Amuc_0167	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Amuc_0169	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Amuc_0170	COG0504	CTP synthase activity
Amuc_0171	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Amuc_0176	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Amuc_0178	COG1322	Protein conserved in bacteria
Amuc_0179	COG0546	phosphoglycolate phosphatase activity
Amuc_0180	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Amuc_0182	COG4591	ABC-type transport system involved in lipoprotein release permease component
Amuc_0187	COG2234	aminopeptidase activity
Amuc_0188	COG2755	lipolytic protein G-D-S-L family
Amuc_0188	COG0657	acetylesterase activity
Amuc_0189	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Amuc_0193	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Amuc_0194	COG2267	carboxylic ester hydrolase activity
Amuc_0198	COG0335	large ribosomal subunit rRNA binding
Amuc_0200	COG0346	lactoylglutathione lyase activity
Amuc_0203	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Amuc_0204	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Amuc_0205	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Amuc_0205	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Amuc_0206	COG0427	acetyl-CoA hydrolase
Amuc_0208	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Amuc_0210	COG0205	6-phosphofructokinase activity
Amuc_0213	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Amuc_0214	COG0028	Belongs to the TPP enzyme family
Amuc_0218	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Amuc_0221	COG0471	metal ion transport
Amuc_0223	COG0351	phosphomethylpyrimidine kinase
Amuc_0230	COG1028	Short-chain dehydrogenase reductase Sdr
Amuc_0232	COG0242	peptide deformylase activity
Amuc_0233	COG1063	alcohol dehydrogenase
Amuc_0236	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Amuc_0237	COG1393	Belongs to the ArsC family
Amuc_0238	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Amuc_0242	COG1187	pseudouridine synthase activity
Amuc_0244	COG0336	Belongs to the RNA methyltransferase TrmD family
Amuc_0245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Amuc_0247	COG0539	negative regulation of cytoplasmic translation
Amuc_0255	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Amuc_0256	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Amuc_0257	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Amuc_0258	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Amuc_0260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Amuc_0263	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Amuc_0263	COG0662	Cupin 2, conserved barrel domain protein
Amuc_0265	COG0416	fatty acid biosynthetic process
Amuc_0266	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Amuc_0268	COG0537	adenosine 5'-monophosphoramidase activity
Amuc_0269	COG0009	L-threonylcarbamoyladenylate synthase
Amuc_0270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Amuc_0271	COG0228	four-way junction DNA binding
Amuc_0275	COG1862	Preprotein translocase
Amuc_0276	COG0343	queuine tRNA-ribosyltransferase activity
Amuc_0277	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Amuc_0279	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Amuc_0280	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Amuc_0281	COG0776	regulation of translation
Amuc_0287	COG0811	peptide transport
Amuc_0290	COG3250	beta-galactosidase activity
Amuc_0291	COG0525	valine-tRNA ligase activity
Amuc_0293	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Amuc_0294	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Amuc_0295	COG0255	Belongs to the universal ribosomal protein uL29 family
Amuc_0296	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Amuc_0297	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Amuc_0298	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Amuc_0300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Amuc_0301	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Amuc_0302	COG0089	rRNA binding
Amuc_0303	COG0088	Forms part of the polypeptide exit tunnel
Amuc_0304	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Amuc_0305	COG0051	transcription antitermination factor activity, RNA binding
Amuc_0306	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Amuc_0307	COG0049	tRNA binding
Amuc_0308	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Amuc_0309	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Amuc_0311	COG3852	Histidine kinase
Amuc_0312	COG2204	response regulator
Amuc_0314	COG1722	exodeoxyribonuclease VII activity
Amuc_0315	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Amuc_0318	COG0795	lipopolysaccharide-transporting ATPase activity
Amuc_0319	COG1160	GTP binding
Amuc_0320	COG0444	Belongs to the ABC transporter superfamily
Amuc_0335	COG0577	efflux transmembrane transporter activity
Amuc_0335	COG1136	(ABC) transporter
Amuc_0337	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Amuc_0346	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Amuc_0347	COG0799	negative regulation of ribosome biogenesis
Amuc_0348	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Amuc_0358	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Amuc_0361	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Amuc_0363	COG0300	oxidoreductase activity
Amuc_0367	COG0038	chloride channel
Amuc_0369	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Amuc_0372	COG0076	glutamate decarboxylase activity
Amuc_0375	COG0167	dihydroorotate dehydrogenase activity
Amuc_0376	COG0352	thiamine-phosphate diphosphorylase activity
Amuc_0380	COG1253	flavin adenine dinucleotide binding
Amuc_0381	COG1253	flavin adenine dinucleotide binding
Amuc_0382	COG1185	polyribonucleotide nucleotidyltransferase activity
Amuc_0383	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Amuc_0384	COG0110	maltose O-acetyltransferase activity
Amuc_0389	COG0101	tRNA pseudouridine synthase activity
Amuc_0390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Amuc_0394	COG4968	Prepilin-type N-terminal cleavage methylation domain
Amuc_0397	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Amuc_0398	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Amuc_0403	COG1136	(ABC) transporter
Amuc_0404	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Amuc_0406	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Amuc_0413	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Amuc_0414	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Amuc_0416	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Amuc_0417	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Amuc_0419	COG2814	Major facilitator Superfamily
Amuc_0421	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Amuc_0422	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Amuc_0422	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Amuc_0423	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Amuc_0424	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Amuc_0425	COG0552	protein localization to endoplasmic reticulum
Amuc_0426	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Amuc_0430	COG1058	Belongs to the CinA family
Amuc_0430	COG1546	Belongs to the CinA family
Amuc_0432	COG0456	acetyltransferase
Amuc_0437	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Amuc_0438	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Amuc_0439	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Amuc_0440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Amuc_0443	COG0758	DNA mediated transformation
Amuc_0444	COG1686	Belongs to the peptidase S11 family
Amuc_0445	COG0012	GTP binding
Amuc_0448	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Amuc_0448	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Amuc_0451	COG3119	arylsulfatase activity
Amuc_0456	COG2259	Doxx family
Amuc_0457	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Amuc_0463	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Amuc_0467	COG2326	polyphosphate kinase activity
Amuc_0468	COG1349	DNA-binding transcription factor activity
Amuc_0471	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Amuc_0472	COG1162	GTPase activity
Amuc_0475	COG0742	ribosomal rna small subunit methyltransferase
Amuc_0478	COG2326	polyphosphate kinase activity
Amuc_0480	COG5434	Belongs to the glycosyl hydrolase 28 family
Amuc_0482	COG1073	alpha beta
Amuc_0483	COG0802	atpase or kinase
Amuc_0485	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Amuc_0486	COG0735	belongs to the Fur family
Amuc_0487	COG0396	ATPase activity
Amuc_0488	COG0719	Fe-S assembly protein
Amuc_0489	COG0719	Fe-S assembly protein
Amuc_0492	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Amuc_0501	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Amuc_0505	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Amuc_0506	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Amuc_0507	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Amuc_0508	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Amuc_0509	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Amuc_0510	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Amuc_0512	COG0356	it plays a direct role in the translocation of protons across the membrane
Amuc_0522	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Amuc_0527	COG1045	serine acetyltransferase
Amuc_0528	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Amuc_0529	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Amuc_0530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Amuc_0532	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Amuc_0534	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Amuc_0535	COG0047	phosphoribosylformylglycinamidine synthase activity
Amuc_0537	COG1363	Peptidase, m42
Amuc_0540	COG1077	Cell shape determining protein MreB Mrl
Amuc_0541	COG1530	ribonuclease E activity
Amuc_0546	COG0848	biopolymer transport protein
Amuc_0549	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Amuc_0552	COG0134	indole-3-glycerol-phosphate synthase activity
Amuc_0553	COG0792	nuclease activity
Amuc_0555	COG1253	flavin adenine dinucleotide binding
Amuc_0557	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Amuc_0559	COG0137	argininosuccinate synthase activity
Amuc_0562	COG0149	triose-phosphate isomerase activity
Amuc_0569	COG1040	competence protein
Amuc_0571	COG3956	TIGRFAM MazG family protein
Amuc_0575	COG1663	tetraacyldisaccharide 4'-kinase activity
Amuc_0576	COG0612	Peptidase, M16
Amuc_0581	COG0673	inositol 2-dehydrogenase activity
Amuc_0582	COG3034	peptidoglycan biosynthetic process
Amuc_0585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Amuc_0586	COG0424	maF-like protein
Amuc_0587	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Amuc_0589	COG2815	serine threonine protein kinase
Amuc_0589	COG0515	serine threonine protein kinase
Amuc_0594	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Amuc_0596	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Amuc_0598	COG0571	ribonuclease III activity
Amuc_0600	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Amuc_0607	COG0708	Exodeoxyribonuclease III
Amuc_0608	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Amuc_0611	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Amuc_0615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Amuc_0616	COG0631	protein serine/threonine phosphatase activity
Amuc_0618	COG2226	methyltransferase
Amuc_0621	COG2076	Multidrug Resistance protein
Amuc_0629	COG2255	four-way junction helicase activity
Amuc_0630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Amuc_0631	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Amuc_0632	COG1215	transferase activity, transferring glycosyl groups
Amuc_0633	COG1216	Glycosyl transferase, family 2
Amuc_0633	COG0463	Glycosyl transferase, family 2
Amuc_0638	COG0438	transferase activity, transferring glycosyl groups
Amuc_0640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Amuc_0642	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Amuc_0644	COG0482	sulfurtransferase activity
Amuc_0645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Amuc_0647	COG2860	membrane
Amuc_0648	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Amuc_0649	COG2001	Belongs to the MraZ family
Amuc_0650	COG0275	rRNA processing
Amuc_0652	COG0768	penicillin binding
Amuc_0653	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Amuc_0654	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Amuc_0655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Amuc_0656	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Amuc_0658	COG0772	Belongs to the SEDS family
Amuc_0659	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Amuc_0660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Amuc_0661	COG1181	Belongs to the D-alanine--D-alanine ligase family
Amuc_0663	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Amuc_0664	COG0860	N-Acetylmuramoyl-L-alanine amidase
Amuc_0665	COG0321	lipoyl(octanoyl) transferase activity
Amuc_0666	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Amuc_0667	COG0066	3-isopropylmalate dehydratase activity
Amuc_0669	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Amuc_0671	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Amuc_0672	COG4608	Belongs to the ABC transporter superfamily
Amuc_0673	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Amuc_0676	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Amuc_0679	COG1137	ATPase activity
Amuc_0681	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Amuc_0684	COG1733	regulation of RNA biosynthetic process
Amuc_0689	COG0017	Asparaginyl-tRNA synthetase
Amuc_0691	COG3118	belongs to the thioredoxin family
Amuc_0701	COG0583	DNA-binding transcription factor activity
Amuc_0702	COG2855	membrane
Amuc_0703	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Amuc_0705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Amuc_0707	COG0602	queuosine metabolic process
Amuc_0708	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Amuc_0709	COG0217	transcriptional regulatory protein
Amuc_0710	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Amuc_0711	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Amuc_0711	COG4651	solute:proton antiporter activity
Amuc_0713	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Amuc_0714	COG4864	UPF0365 protein
Amuc_0716	COG2022	thiamine diphosphate biosynthetic process
Amuc_0717	COG0531	amino acid
Amuc_0719	COG0628	permease
Amuc_0720	COG0019	diaminopimelate decarboxylase activity
Amuc_0721	COG0191	fructose-bisphosphate aldolase activity
Amuc_0728	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Amuc_0736	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Amuc_0737	COG0516	GMP reductase activity
Amuc_0737	COG0517	IMP dehydrogenase activity
Amuc_0738	COG0519	Catalyzes the synthesis of GMP from XMP
Amuc_0738	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Amuc_0740	COG0546	phosphoglycolate phosphatase activity
Amuc_0744	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Amuc_0747	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Amuc_0748	COG0196	riboflavin kinase activity
Amuc_0749	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Amuc_0752	COG1408	metallophosphoesterase
Amuc_0754	COG1216	Glycosyl transferase, family 2
Amuc_0754	COG1442	glycosyl transferase family 8
Amuc_0756	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Amuc_0757	COG1216	Glycosyl transferase, family 2
Amuc_0761	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Amuc_0761	COG2755	lipolytic protein G-D-S-L family
Amuc_0766	COG0490	domain, Protein
Amuc_0766	COG0471	metal ion transport
Amuc_0772	COG0588	phosphoglycerate mutase activity
Amuc_0774	COG0477	Major facilitator Superfamily
Amuc_0775	COG1607	acyl-coa hydrolase
Amuc_0777	COG1028	Short-chain dehydrogenase reductase Sdr
Amuc_0779	COG1525	nuclease
Amuc_0782	COG1475	DNA binding
Amuc_0783	COG3969	phosphoadenosine phosphosulfate
Amuc_0785	COG0473	3-isopropylmalate dehydrogenase activity
Amuc_0792	COG0535	radical SAM domain protein
Amuc_0795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Amuc_0796	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Amuc_0798	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Amuc_0802	COG1733	regulation of RNA biosynthetic process
Amuc_0804	COG0107	imidazoleglycerol-phosphate synthase activity
Amuc_0806	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Amuc_0808	COG1643	Atp-dependent helicase
Amuc_0809	COG0440	acetolactate synthase activity
Amuc_0810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Amuc_0812	COG0445	tRNA wobble uridine modification
Amuc_0813	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Amuc_0813	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Amuc_0814	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Amuc_0816	COG0592	DNA-directed DNA polymerase activity
Amuc_0821	COG0791	NLP P60 protein
Amuc_0821	COG1388	LysM domain
Amuc_0822	COG0084	hydrolase, TatD family'
Amuc_0824	COG3250	beta-galactosidase activity
Amuc_0827	COG2205	protein histidine kinase activity
Amuc_0828	COG0745	RESPONSE REGULATOR receiver
Amuc_0830	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Amuc_0836	COG0542	response to heat
Amuc_0838	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Amuc_0840	COG0659	secondary active sulfate transmembrane transporter activity
Amuc_0841	COG0165	Argininosuccinate lyase
Amuc_0844	COG0148	phosphopyruvate hydratase activity
Amuc_0845	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Amuc_0847	COG3481	metal-dependent phosphohydrolase, HD sub domain
Amuc_0849	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Amuc_0850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Amuc_0856	COG2985	domain, Protein
Amuc_0856	COG0490	domain, Protein
Amuc_0859	COG0471	metal ion transport
Amuc_0864	COG2194	sulfuric ester hydrolase activity
Amuc_0865	COG1592	Rubrerythrin
Amuc_0867	COG1363	Peptidase, m42
Amuc_0868	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Amuc_0870	COG1785	Belongs to the alkaline phosphatase family
Amuc_0871	COG1970	mechanosensitive ion channel activity
Amuc_0872	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Amuc_0874	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Amuc_0876	COG2217	Heavy metal translocating P-type atpase
Amuc_0877	COG0497	DNA recombination
Amuc_0878	COG0321	lipoyl(octanoyl) transferase activity
Amuc_0878	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Amuc_0879	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Amuc_0885	COG0508	dehydrogenase complex catalyzes the overall conversion of
Amuc_0886	COG0022	dehydrogenase e1 component
Amuc_0887	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Amuc_0888	COG0789	Transcriptional regulator
Amuc_0889	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Amuc_0890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Amuc_0903	COG5632	N-Acetylmuramoyl-L-alanine amidase
Amuc_0903	COG3409	Peptidoglycan-binding domain 1 protein
Amuc_0904	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Amuc_0909	COG1690	Belongs to the RtcB family
Amuc_0911	COG2814	Major facilitator Superfamily
Amuc_0913	COG2096	Adenosyltransferase
Amuc_0915	COG0557	exoribonuclease II activity
Amuc_0917	COG0826	peptidase U32
Amuc_0918	COG0285	dihydrofolate synthase activity
Amuc_0920	COG0673	inositol 2-dehydrogenase activity
Amuc_0921	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Amuc_0922	COG0737	Belongs to the 5'-nucleotidase family
Amuc_0924	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Amuc_0925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Amuc_0927	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Amuc_0928	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Amuc_0929	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Amuc_0930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Amuc_0931	COG0200	Binds to the 23S rRNA
Amuc_0933	COG0201	protein transport
Amuc_0934	COG0563	adenylate kinase activity
Amuc_0935	COG0024	Methionine aminopeptidase
Amuc_0938	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Amuc_0939	COG1442	glycosyl transferase family 8
Amuc_0941	COG1216	Glycosyl transferase, family 2
Amuc_0943	COG1216	Glycosyl transferase, family 2
Amuc_0945	COG1216	Glycosyl transferase, family 2
Amuc_0946	COG0693	protein deglycase activity
Amuc_0947	COG0508	dehydrogenase complex catalyzes the overall conversion of
Amuc_0948	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Amuc_0949	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Amuc_0951	COG1966	Carbon starvation protein
Amuc_0953	COG3119	arylsulfatase activity
Amuc_0955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Amuc_0956	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Amuc_0957	COG0195	Participates in both transcription termination and antitermination
Amuc_0958	COG0708	Exodeoxyribonuclease III
Amuc_0959	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Amuc_0960	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Amuc_0961	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
Amuc_0963	COG1716	ATPase activity
Amuc_0963	COG1131	(ABC) transporter
Amuc_0963	COG0842	Transport permease protein
Amuc_0967	COG0724	RNA recognition motif
Amuc_0968	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Amuc_0972	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Amuc_0974	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Amuc_0975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Amuc_0978	COG1490	D-aminoacyl-tRNA deacylase activity
Amuc_0984	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Amuc_0985	COG1053	succinate dehydrogenase
Amuc_0994	COG1028	Short-chain dehydrogenase reductase Sdr
Amuc_0996	COG0488	(ABC) transporter
Amuc_0999	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Amuc_1001	COG1028	Short-chain dehydrogenase reductase Sdr
Amuc_1003	COG1073	alpha beta
Amuc_1017	COG2267	carboxylic ester hydrolase activity
Amuc_1018	COG2095	MarC family integral membrane protein
Amuc_1026	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Amuc_1027	COG0488	(ABC) transporter
Amuc_1029	COG0697	spore germination
Amuc_1031	COG0215	cysteine-tRNA ligase activity
Amuc_1033	COG3119	arylsulfatase activity
Amuc_1036	COG0481	GTPase activity
Amuc_1040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Amuc_1041	COG0085	RNA polymerase activity
Amuc_1042	COG0222	ribosome binding
Amuc_1043	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Amuc_1044	COG0081	regulation of translation
Amuc_1045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Amuc_1046	COG0250	Participates in transcription elongation, termination and antitermination
Amuc_1048	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Amuc_1049	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Amuc_1051	COG0740	serine-type endopeptidase activity
Amuc_1052	COG0544	peptidyl-prolyl cis-trans isomerase activity
Amuc_1055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Amuc_1059	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Amuc_1067	COG2226	methyltransferase
Amuc_1068	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Amuc_1069	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Amuc_1072	COG1902	pentaerythritol trinitrate reductase activity
Amuc_1072	COG0446	pyridine nucleotide-disulphide oxidoreductase
Amuc_1074	COG3119	arylsulfatase activity
Amuc_1075	COG0514	ATP-dependent DNA helicase (RecQ)
Amuc_1079	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Amuc_1080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Amuc_1088	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Amuc_1091	COG1858	cytochrome C peroxidase
Amuc_1092	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Amuc_1093	COG0590	tRNA wobble adenosine to inosine editing
Amuc_1094	COG1940	carbohydrate kinase activity
Amuc_1095	COG2217	Heavy metal translocating P-type atpase
Amuc_1096	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Amuc_1097	COG0237	dephospho-CoA kinase activity
Amuc_1103	COG1363	Peptidase, m42
Amuc_1104	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Amuc_1106	COG0006	proline dipeptidase activity
Amuc_1107	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Amuc_1110	COG0745	RESPONSE REGULATOR receiver
Amuc_1111	COG0129	dihydroxy-acid dehydratase activity
Amuc_1118	COG1368	sulfuric ester hydrolase activity
Amuc_1125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Amuc_1126	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Amuc_1131	COG0534	Mate efflux family protein
Amuc_1132	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Amuc_1134	COG1876	peptidase activity
Amuc_1143	COG3209	COG3209 Rhs family protein
Amuc_1151	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Amuc_1152	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Amuc_1153	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Amuc_1154	COG2205	protein histidine kinase activity
Amuc_1157	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Amuc_1160	COG0667	Aldo Keto reductase
Amuc_1161	COG0789	Transcriptional regulator
Amuc_1170	COG0714	Associated with various cellular activities
Amuc_1171	COG2311	Membrane
Amuc_1176	COG1090	epimerase
Amuc_1178	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Amuc_1179	COG1119	ATPase activity
Amuc_1180	COG2186	Transcriptional regulator
Amuc_1184	COG0148	phosphopyruvate hydratase activity
Amuc_1186	COG1477	protein flavinylation
Amuc_1189	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Amuc_1191	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Amuc_1195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Amuc_1197	COG1199	ATP-dependent helicase activity
Amuc_1198	COG1122	ATPase activity
Amuc_1203	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Amuc_1205	COG0359	binds to the 23S rRNA
Amuc_1206	COG0138	bifunctional purine biosynthesis protein purh
Amuc_1207	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Amuc_1208	COG0736	holo-[acyl-carrier-protein] synthase activity
Amuc_1210	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Amuc_1211	COG5632	N-Acetylmuramoyl-L-alanine amidase
Amuc_1211	COG3409	Peptidoglycan-binding domain 1 protein
Amuc_1212	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Amuc_1214	COG0437	4 iron, 4 sulfur cluster binding
Amuc_1218	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Amuc_1223	COG0284	orotidine-5'-phosphate decarboxylase activity
Amuc_1227	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Amuc_1228	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Amuc_1231	COG2003	Belongs to the UPF0758 family
Amuc_1232	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Amuc_1232	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Amuc_1233	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Amuc_1234	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Amuc_1235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Amuc_1236	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Amuc_1237	COG0322	excinuclease ABC activity
Amuc_1238	COG0811	peptide transport
Amuc_1239	COG0848	biopolymer transport protein
Amuc_1241	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Amuc_1243	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Amuc_1245	COG1482	cell wall glycoprotein biosynthetic process
Amuc_1247	COG1757	Na H antiporter
Amuc_1248	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Amuc_1249	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Amuc_1250	COG0505	Belongs to the CarA family
Amuc_1251	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Amuc_1253	COG0069	glutamate synthase activity
Amuc_1253	COG0067	glutamate synthase
Amuc_1253	COG0070	glutamate synthase
Amuc_1254	COG0706	membrane insertase activity
Amuc_1255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Amuc_1257	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Amuc_1259	COG2755	lipolytic protein G-D-S-L family
Amuc_1259	COG0657	acetylesterase activity
Amuc_1261	COG0676	glucose-6-phosphate 1-epimerase activity
Amuc_1265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Amuc_1268	COG1760	l-serine dehydratase
Amuc_1269	COG0492	ferredoxin-NADP+ reductase activity
Amuc_1269	COG3118	belongs to the thioredoxin family
Amuc_1279	COG1408	metallophosphoesterase
Amuc_1281	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Amuc_1282	COG0545	Peptidyl-prolyl cis-trans isomerase
Amuc_1285	COG0187	DNA topoisomerase II activity
Amuc_1286	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Amuc_1288	COG0826	peptidase U32
Amuc_1290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Amuc_1294	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Amuc_1296	COG1116	anion transmembrane transporter activity
Amuc_1298	COG2895	sulfate adenylyltransferase (ATP) activity
Amuc_1298	COG0529	Catalyzes the synthesis of activated sulfate
Amuc_1299	COG0175	sulfate reduction
Amuc_1300	COG0175	sulfate reduction
Amuc_1304	COG0581	inorganic phosphate transmembrane transporter activity
Amuc_1305	COG0573	inorganic phosphate transmembrane transporter activity
Amuc_1307	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Amuc_1309	COG2017	converts alpha-aldose to the beta-anomer
Amuc_1312	COG0612	Peptidase, M16
Amuc_1318	COG0233	cytoplasmic translational termination
Amuc_1319	COG0528	UMP kinase activity
Amuc_1320	COG0668	transmembrane transport
Amuc_1321	COG0450	alkyl hydroperoxide reductase
Amuc_1322	COG0733	neurotransmitter:sodium symporter activity
Amuc_1327	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Amuc_1329	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Amuc_1330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Amuc_1377	COG0305	Participates in initiation and elongation during chromosome replication
Amuc_1379	COG0842	Transport permease protein
Amuc_1380	COG0842	Transport permease protein
Amuc_1381	COG1131	(ABC) transporter
Amuc_1383	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Amuc_1384	COG1183	phosphatidylcholine synthase activity
Amuc_1386	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Amuc_1388	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Amuc_1389	COG1028	Short-chain dehydrogenase reductase Sdr
Amuc_1393	COG0156	8-amino-7-oxononanoate synthase activity
Amuc_1396	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Amuc_1397	COG0124	histidyl-tRNA synthetase
Amuc_1398	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Amuc_1399	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Amuc_1400	COG0298	carbon dioxide binding
Amuc_1405	COG0438	transferase activity, transferring glycosyl groups
Amuc_1406	COG0443	Heat shock 70 kDa protein
Amuc_1407	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Amuc_1408	COG0459	protein refolding
Amuc_1416	COG0632	four-way junction helicase activity
Amuc_1418	COG0126	phosphoglycerate kinase activity
Amuc_1420	COG1082	Xylose isomerase domain protein TIM barrel
Amuc_1424	COG2271	Major facilitator Superfamily
Amuc_1427	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Amuc_1429	COG0037	tRNA processing
Amuc_1430	COG0254	rRNA binding
Amuc_1435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Amuc_1436	COG0039	L-malate dehydrogenase activity
Amuc_1440	COG0778	Nitroreductase
Amuc_1441	COG0564	pseudouridine synthase activity
Amuc_1445	COG1126	abc transporter atp-binding protein
Amuc_1446	COG0765	amino acid transport
Amuc_1447	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Amuc_1448	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Amuc_1452	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Amuc_1457	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Amuc_1458	COG1872	DUF167
Amuc_1460	COG0484	heat shock protein binding
Amuc_1461	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Amuc_1463	COG5434	Belongs to the glycosyl hydrolase 28 family
Amuc_1466	COG0277	FAD linked oxidase domain protein
Amuc_1471	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Amuc_1472	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Amuc_1474	COG0131	Imidazoleglycerol-phosphate dehydratase
Amuc_1475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Amuc_1476	COG0360	Binds together with S18 to 16S ribosomal RNA
Amuc_1477	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Amuc_1480	COG1686	Belongs to the peptidase S11 family
Amuc_1481	COG0205	6-phosphofructokinase activity
Amuc_1483	COG0428	transporter
Amuc_1484	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Amuc_1487	COG3977	Valine--pyruvate aminotransferase
Amuc_1488	COG1561	YicC-like family, N-terminal region
Amuc_1490	COG0471	metal ion transport
Amuc_1490	COG3273	potassium ion transport
Amuc_1491	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Amuc_1494	COG1575	Belongs to the MenA family. Type 1 subfamily
Amuc_1500	COG0726	polysaccharide deacetylase
Amuc_1501	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Amuc_1501	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Amuc_1505	COG0202	RNA polymerase activity
Amuc_1506	COG0203	ribosomal protein L17
Amuc_1507	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Amuc_1509	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Amuc_1512	COG2885	chlorophyll binding
Amuc_1519	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Amuc_1527	COG0667	Aldo Keto reductase
Amuc_1528	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Amuc_1531	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Amuc_1532	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Amuc_1533	COG0134	indole-3-glycerol-phosphate synthase activity
Amuc_1534	COG0135	phosphoribosylanthranilate isomerase activity
Amuc_1536	COG0159	tryptophan synthase activity
Amuc_1539	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Amuc_1540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Amuc_1542	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Amuc_1549	COG0561	phosphatase activity
Amuc_1551	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Amuc_1552	COG2223	nitrite transmembrane transporter activity
Amuc_1555	COG0556	nucleotide-excision repair
Amuc_1556	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Amuc_1557	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Amuc_1558	COG0750	zinc metalloprotease
Amuc_1561	COG1074	ATP-dependent DNA helicase activity
Amuc_1563	COG0697	spore germination
Amuc_1565	COG2373	Large extracellular alpha-helical protein
Amuc_1566	COG1979	alcohol dehydrogenase
Amuc_1567	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Amuc_1572	COG0372	Belongs to the citrate synthase family
Amuc_1576	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Amuc_1578	COG1187	pseudouridine synthase activity
Amuc_1580	COG0105	UTP biosynthetic process
Amuc_1581	COG1215	transferase activity, transferring glycosyl groups
Amuc_1582	COG0463	Glycosyl transferase, family 2
Amuc_1584	COG1459	type II secretion system
Amuc_1585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Amuc_1587	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Amuc_1590	COG0728	peptidoglycan biosynthetic process
Amuc_1591	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Amuc_1591	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Amuc_1593	COG1649	PFAM Uncharacterised BCR, COG1649
Amuc_1594	COG1691	(AIR) carboxylase
Amuc_1595	COG0037	tRNA processing
Amuc_1596	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
Amuc_1597	COG0142	geranyltranstransferase activity
Amuc_1600	COG2151	metal-sulfur cluster biosynthetic enzyme
Amuc_1604	COG1007	ATP synthesis coupled electron transport
Amuc_1605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Amuc_1607	COG0713	ATP synthesis coupled electron transport
Amuc_1608	COG0839	Belongs to the complex I subunit 6 family
Amuc_1610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Amuc_1611	COG1034	ATP synthesis coupled electron transport
Amuc_1612	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Amuc_1613	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Amuc_1614	COG0649	NAD binding
Amuc_1616	COG0726	polysaccharide deacetylase
Amuc_1618	COG0307	riboflavin synthase, alpha
Amuc_1619	COG2264	protein methyltransferase activity
Amuc_1620	COG3210	domain, Protein
Amuc_1621	COG1640	4-alpha-glucanotransferase
Amuc_1623	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Amuc_1624	COG1030	water channel activity
Amuc_1625	COG0358	DNA primase activity
Amuc_1626	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Amuc_1627	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
Amuc_1630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Amuc_1631	COG0793	Belongs to the peptidase S41A family
Amuc_1633	COG1643	Atp-dependent helicase
Amuc_1638	COG1450	Type ii and iii secretion system protein
Amuc_1641	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Amuc_1645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Amuc_1646	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Amuc_1648	COG0268	Binds directly to 16S ribosomal RNA
Amuc_1649	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Amuc_1650	COG0028	Belongs to the TPP enzyme family
Amuc_1652	COG0688	phosphatidylethanolamine metabolic process
Amuc_1653	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Amuc_1654	COG0495	leucyl-tRNA aminoacylation
Amuc_1655	COG3119	arylsulfatase activity
Amuc_1658	COG1166	arginine decarboxylase activity
Amuc_1666	COG3250	beta-galactosidase activity
Amuc_1667	COG3250	beta-galactosidase activity
Amuc_1668	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Amuc_1669	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Amuc_1671	COG0205	6-phosphofructokinase activity
Amuc_1680	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Amuc_1681	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Amuc_1682	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Amuc_1684	COG4771	TonB-dependent receptor
Amuc_1688	COG0402	S-adenosylhomocysteine deaminase activity
Amuc_1689	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Amuc_1694	COG1294	oxidase, subunit
Amuc_1695	COG1271	oxidase subunit
Amuc_1697	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Amuc_1701	COG1846	Transcriptional regulator
Amuc_1706	COG2949	membrane
Amuc_1710	COG0514	ATP-dependent DNA helicase (RecQ)
Amuc_1712	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Amuc_1713	COG0045	succinate-CoA ligase (ADP-forming) activity
Amuc_1726	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Amuc_1727	COG2205	protein histidine kinase activity
Amuc_1730	COG0113	porphobilinogen synthase activity
Amuc_1732	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Amuc_1737	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Amuc_1746	COG3475	LICD family
Amuc_1747	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Amuc_1749	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Amuc_1750	COG3475	LICD family
Amuc_1751	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Amuc_1753	COG2166	iron-sulfur cluster assembly
Amuc_1754	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Amuc_1756	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Amuc_1757	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Amuc_1758	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Amuc_1759	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Amuc_1760	COG1131	(ABC) transporter
Amuc_1763	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Amuc_1766	COG1215	transferase activity, transferring glycosyl groups
Amuc_1768	COG2967	ApaG domain
Amuc_1770	COG1522	sequence-specific DNA binding
Amuc_1771	COG0436	Aminotransferase
Amuc_1774	COG0423	glycine-tRNA ligase activity
Amuc_1775	COG0656	L-ascorbic acid biosynthetic process
Amuc_1781	COG0714	Associated with various cellular activities
Amuc_1782	COG0154	amidase activity
Amuc_1783	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Amuc_1790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Amuc_1791	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Amuc_1793	COG2755	lipolytic protein G-D-S-L family
Amuc_1793	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Amuc_1798	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Amuc_1800	COG0656	L-ascorbic acid biosynthetic process
Amuc_1802	COG0667	Aldo Keto reductase
Amuc_1803	COG1408	metallophosphoesterase
Amuc_1807	COG0667	Aldo Keto reductase
Amuc_1809	COG2249	NAD(P)H dehydrogenase (quinone) activity
Amuc_1810	COG0789	Transcriptional regulator
Amuc_1813	COG0534	Mate efflux family protein
Amuc_1817	COG1091	dTDP-4-dehydrorhamnose reductase activity
Amuc_1820	COG1837	Belongs to the UPF0109 family
Amuc_1821	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Amuc_1822	COG0363	glucosamine-6-phosphate deaminase activity
Amuc_1825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Amuc_1827	COG1741	Belongs to the pirin family
Amuc_1830	COG1070	Carbohydrate kinase
Amuc_1833	COG0738	Major facilitator superfamily
Amuc_1836	COG1595	DNA-templated transcription, initiation
Amuc_1840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Amuc_1844	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Amuc_1847	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Amuc_1850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Amuc_1851	COG4608	Belongs to the ABC transporter superfamily
Amuc_1852	COG0444	Belongs to the ABC transporter superfamily
Amuc_1853	COG4166	transmembrane transport
Amuc_1854	COG4239	(ABC) transporter, permease
Amuc_1855	COG0601	transmembrane transport
Amuc_1859	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Amuc_1860	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Amuc_1861	COG3738	Protein conserved in bacteria
Amuc_1862	COG0151	Belongs to the GarS family
Amuc_1865	COG0811	peptide transport
Amuc_1867	COG0242	peptide deformylase activity
Amuc_1874	COG2010	Cytochrome c
Amuc_1876	COG3258	Cytochrome c
Amuc_1879	COG3274	enterobacterial common antigen metabolic process
Amuc_1880	COG0538	isocitrate dehydrogenase activity
Amuc_1883	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Amuc_1884	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Amuc_1885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Amuc_1887	COG0668	transmembrane transport
Amuc_1888	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Amuc_1888	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Amuc_1889	COG0805	protein transport
Amuc_1890	COG1968	undecaprenyl-diphosphatase activity
Amuc_1894	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Amuc_1895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Amuc_1897	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Amuc_1899	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Amuc_1901	COG1408	metallophosphoesterase
Amuc_1906	COG4974	Belongs to the 'phage' integrase family
Amuc_1911	COG1454	alcohol dehydrogenase
Amuc_1913	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Amuc_1916	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Amuc_1918	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Amuc_1918	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Amuc_1919	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Amuc_1926	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Amuc_1928	COG4607	ABC-type enterochelin transport system periplasmic component
Amuc_1929	COG4604	ABC transporter, ATP-binding protein
Amuc_1930	COG4605	iron ion homeostasis
Amuc_1931	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Amuc_1938	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Amuc_1938	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Amuc_1941	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Amuc_1942	COG2195	Cleaves the N-terminal amino acid of tripeptides
Amuc_1949	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Amuc_1954	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Amuc_1954	COG0519	Catalyzes the synthesis of GMP from XMP
Amuc_1956	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Amuc_1961	COG0646	methionine synthase
Amuc_1961	COG1410	methionine synthase
Amuc_1962	COG2966	Psort location CytoplasmicMembrane, score
Amuc_1963	COG3610	response to peptide
Amuc_1964	COG0460	homoserine dehydrogenase
Amuc_1965	COG0527	aspartate kinase activity
Amuc_1968	COG5522	Integral membrane protein (intg_mem_TP0381)
Amuc_1970	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Amuc_1971	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Amuc_1972	COG1194	a g-specific adenine glycosylase
Amuc_1973	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Amuc_1974	COG0574	Belongs to the PEP-utilizing enzyme family
Amuc_1974	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Amuc_1975	COG0166	Belongs to the GPI family
Amuc_1977	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Amuc_1983	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Amuc_1983	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Amuc_1990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Amuc_1991	COG2818	Glycosylase
Amuc_1995	COG3033	Beta-eliminating lyase
Amuc_1998	COG0072	phenylalanine-tRNA ligase activity
Amuc_1998	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Amuc_2002	COG0326	Molecular chaperone. Has ATPase activity
Amuc_2003	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Amuc_2008	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Amuc_2011	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Amuc_2012	COG1959	2 iron, 2 sulfur cluster binding
Amuc_2015	COG0352	thiamine-phosphate diphosphorylase activity
Amuc_2016	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Amuc_2020	COG1703	isobutyryl-CoA mutase activity
Amuc_2024	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Amuc_2026	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Amuc_2027	COG0418	dihydroorotase activity
Amuc_2029	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Amuc_2033	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Amuc_2036	COG0534	Mate efflux family protein
Amuc_2037	COG0489	protein tyrosine kinase activity
Amuc_2039	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Amuc_2040	COG0339	signal peptide processing
Amuc_2041	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Amuc_2043	COG1538	Outer membrane efflux protein
Amuc_2046	COG4112	unkown
Amuc_2049	COG0038	chloride channel
Amuc_2051	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Amuc_2052	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Amuc_2053	COG0586	Pfam SNARE associated Golgi protein
Amuc_2066	COG1012	belongs to the aldehyde dehydrogenase family
Amuc_2070	COG0753	catalase activity
Amuc_2071	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Amuc_2072	COG1592	Rubrerythrin
Amuc_2074	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Amuc_2076	COG1674	ftsk spoiiie
Amuc_2078	COG0489	protein tyrosine kinase activity
Amuc_2080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Amuc_2082	COG0438	transferase activity, transferring glycosyl groups
Amuc_2084	COG0438	transferase activity, transferring glycosyl groups
Amuc_2092	COG0110	maltose O-acetyltransferase activity
Amuc_2094	COG1216	Glycosyl transferase, family 2
Amuc_2098	COG2755	lipolytic protein G-D-S-L family
Amuc_2098	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Amuc_2102	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Amuc_2103	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Amuc_2103	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Amuc_2104	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Amuc_2106	COG0280	phosphate acetyltransferase
Amuc_2106	COG0281	malic enzyme
Amuc_2109	COG1472	Belongs to the glycosyl hydrolase 3 family
Amuc_2113	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Amuc_2115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Amuc_2116	COG1063	alcohol dehydrogenase
Amuc_2119	COG0714	Associated with various cellular activities
Amuc_2121	COG0193	aminoacyl-tRNA hydrolase activity
Amuc_2122	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Amuc_2125	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Amuc_2129	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
Amuc_2132	COG0375	protein maturation
Amuc_2137	COG0778	Nitroreductase
Amuc_2138	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Amuc_2142	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Amuc_2142	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Amuc_2144	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Amuc_2144	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Amuc_2148	COG3525	Glycosyl hydrolase, family 20, catalytic domain
Amuc_2149	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Amuc_2157	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Amuc_2158	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Amuc_2161	COG0318	PFAM AMP-dependent synthetase and ligase
Amuc_2167	COG0339	signal peptide processing
Amuc_2169	COG0018	arginyl-trna synthetase
Amuc_2176	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Amuc_2177	COG0653	protein targeting