locus-tag	class	description
J5W67_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W67_00010	COG1131	(ABC) transporter
J5W67_00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W67_00035	COG0564	pseudouridine synthase activity
J5W67_00040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W67_00045	COG0077	Prephenate dehydratase
J5W67_00045	COG1605	Chorismate mutase
J5W67_00055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W67_00060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W67_00065	COG0513	Belongs to the DEAD box helicase family
J5W67_00075	COG0673	inositol 2-dehydrogenase activity
J5W67_00100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5W67_00115	COG1971	Probably functions as a manganese efflux pump
J5W67_00135	COG0657	acetylesterase activity
J5W67_00135	COG2755	lipolytic protein G-D-S-L family
J5W67_00175	COG0442	prolyl-tRNA aminoacylation
J5W67_00220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W67_00225	COG0402	S-adenosylhomocysteine deaminase activity
J5W67_00245	COG4771	TonB-dependent receptor
J5W67_00280	COG3896	Chloramphenicol phosphotransferase-like protein
J5W67_00295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W67_00300	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W67_00340	COG0205	6-phosphofructokinase activity
J5W67_00355	COG1228	amidohydrolase
J5W67_00365	COG1335	isochorismatase
J5W67_00370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_00375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W67_00380	COG3250	beta-galactosidase activity
J5W67_00385	COG3250	beta-galactosidase activity
J5W67_00390	COG3250	beta-galactosidase activity
J5W67_00400	COG1166	arginine decarboxylase activity
J5W67_00420	COG0495	leucyl-tRNA aminoacylation
J5W67_00425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W67_00445	COG0028	Belongs to the TPP enzyme family
J5W67_00450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W67_00455	COG0268	Binds directly to 16S ribosomal RNA
J5W67_00465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W67_00470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W67_00495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W67_00510	COG1450	Type ii and iii secretion system protein
J5W67_00520	COG0617	tRNA 3'-terminal CCA addition
J5W67_00535	COG1643	Atp-dependent helicase
J5W67_00540	COG0575	Belongs to the CDS family
J5W67_00545	COG0793	Belongs to the peptidase S41A family
J5W67_00550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W67_00565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W67_00570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5W67_00575	COG0358	DNA primase activity
J5W67_00580	COG1030	water channel activity
J5W67_00585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W67_00595	COG1640	4-alpha-glucanotransferase
J5W67_00615	COG0307	riboflavin synthase, alpha
J5W67_00625	COG0726	polysaccharide deacetylase
J5W67_00630	COG0649	NAD binding
J5W67_00635	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W67_00640	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W67_00645	COG1034	ATP synthesis coupled electron transport
J5W67_00650	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W67_00660	COG0839	Belongs to the complex I subunit 6 family
J5W67_00665	COG0713	ATP synthesis coupled electron transport
J5W67_00675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W67_00680	COG1007	ATP synthesis coupled electron transport
J5W67_00700	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W67_00715	COG0142	geranyltranstransferase activity
J5W67_00720	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W67_00725	COG1606	tRNA processing
J5W67_00730	COG1691	(AIR) carboxylase
J5W67_00735	COG1649	PFAM Uncharacterised BCR, COG1649
J5W67_00745	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W67_00745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W67_00750	COG0728	peptidoglycan biosynthetic process
J5W67_00780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W67_00790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W67_00795	COG1459	type II secretion system
J5W67_00805	COG0463	Glycosyl transferase, family 2
J5W67_00810	COG1215	transferase activity, transferring glycosyl groups
J5W67_00815	COG0105	UTP biosynthetic process
J5W67_00825	COG1187	pseudouridine synthase activity
J5W67_00835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W67_00855	COG3647	Membrane
J5W67_00860	COG0372	Belongs to the citrate synthase family
J5W67_00865	COG1214	PFAM Peptidase M22, glycoprotease
J5W67_00915	COG1979	alcohol dehydrogenase
J5W67_00920	COG2373	Large extracellular alpha-helical protein
J5W67_00925	COG0697	spore germination
J5W67_00940	COG1074	ATP-dependent DNA helicase activity
J5W67_00985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W67_00990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W67_01000	COG0556	nucleotide-excision repair
J5W67_01035	COG0738	Major facilitator superfamily
J5W67_01040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W67_01050	COG0561	phosphatase activity
J5W67_01095	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W67_01300	COG0305	Participates in initiation and elongation during chromosome replication
J5W67_01315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W67_01320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W67_01335	COG0159	tryptophan synthase activity
J5W67_01345	COG0135	phosphoribosylanthranilate isomerase activity
J5W67_01350	COG0134	indole-3-glycerol-phosphate synthase activity
J5W67_01355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W67_01360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W67_01370	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W67_01375	COG0667	Aldo Keto reductase
J5W67_01410	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W67_01450	COG2885	chlorophyll binding
J5W67_01465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W67_01480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W67_01500	COG0203	ribosomal protein L17
J5W67_01505	COG0202	RNA polymerase activity
J5W67_01525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W67_01525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W67_01530	COG0726	polysaccharide deacetylase
J5W67_01555	COG0710	3-dehydroquinate dehydratase activity
J5W67_01575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W67_01580	COG3273	potassium ion transport
J5W67_01580	COG0471	metal ion transport
J5W67_01590	COG1561	YicC-like family, N-terminal region
J5W67_01595	COG3977	Valine--pyruvate aminotransferase
J5W67_01610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W67_01615	COG0428	transporter
J5W67_01620	COG3152	Membrane
J5W67_01625	COG0205	6-phosphofructokinase activity
J5W67_01630	COG1686	Belongs to the peptidase S11 family
J5W67_01645	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W67_01660	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W67_01670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W67_01675	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W67_01685	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W67_01690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W67_01715	COG0277	FAD linked oxidase domain protein
J5W67_01735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W67_01740	COG0484	heat shock protein binding
J5W67_01745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W67_01750	COG1872	DUF167
J5W67_01755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5W67_01790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W67_01810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W67_01815	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W67_01840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W67_01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5W67_01850	COG0765	amino acid transport
J5W67_01930	COG0564	pseudouridine synthase activity
J5W67_01935	COG0778	Nitroreductase
J5W67_01955	COG0039	L-malate dehydrogenase activity
J5W67_01960	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W67_01985	COG0254	rRNA binding
J5W67_01990	COG0037	tRNA processing
J5W67_02000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W67_02025	COG2271	Major facilitator Superfamily
J5W67_02035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W67_02045	COG0126	phosphoglycerate kinase activity
J5W67_02055	COG0632	four-way junction helicase activity
J5W67_02100	COG0459	protein refolding
J5W67_02105	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W67_02110	COG0443	Heat shock 70 kDa protein
J5W67_02115	COG0438	transferase activity, transferring glycosyl groups
J5W67_02135	COG0298	carbon dioxide binding
J5W67_02140	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W67_02145	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W67_02155	COG0124	histidyl-tRNA synthetase
J5W67_02160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W67_02190	COG3209	COG3209 Rhs family protein
J5W67_02230	COG0156	8-amino-7-oxononanoate synthase activity
J5W67_02245	COG1028	Short-chain dehydrogenase reductase Sdr
J5W67_02250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W67_02270	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W67_02280	COG1183	phosphatidylcholine synthase activity
J5W67_02285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W67_02295	COG1131	(ABC) transporter
J5W67_02300	COG0842	Transport permease protein
J5W67_02305	COG0842	Transport permease protein
J5W67_02315	COG3468	outer membrane autotransporter barrel domain protein
J5W67_02325	COG0456	acetyltransferase
J5W67_02340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W67_02345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W67_02355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W67_02365	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W67_02370	COG4335	DNA alkylation repair
J5W67_02400	COG0733	neurotransmitter:sodium symporter activity
J5W67_02405	COG0450	alkyl hydroperoxide reductase
J5W67_02415	COG0668	transmembrane transport
J5W67_02420	COG0528	UMP kinase activity
J5W67_02425	COG0233	cytoplasmic translational termination
J5W67_02435	COG0612	Peptidase, M16
J5W67_02470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W67_02485	COG0573	inorganic phosphate transmembrane transporter activity
J5W67_02490	COG0581	inorganic phosphate transmembrane transporter activity
J5W67_02495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W67_02570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W67_02580	COG0826	peptidase U32
J5W67_02595	COG0187	DNA topoisomerase II activity
J5W67_02605	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W67_02610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W67_02620	COG1408	metallophosphoesterase
J5W67_02655	COG0492	ferredoxin-NADP+ reductase activity
J5W67_02655	COG3118	belongs to the thioredoxin family
J5W67_02660	COG1760	l-serine dehydratase
J5W67_02670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W67_02685	COG0259	pyridoxamine-phosphate oxidase activity
J5W67_02690	COG0676	glucose-6-phosphate 1-epimerase activity
J5W67_02710	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5W67_02715	COG0594	ribonuclease P activity
J5W67_02720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5W67_02725	COG0706	membrane insertase activity
J5W67_02730	COG1234	tRNA 3'-trailer cleavage
J5W67_02735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W67_02745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W67_02755	COG0848	biopolymer transport protein
J5W67_02760	COG0811	peptide transport
J5W67_02770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W67_02780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W67_02785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W67_02790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W67_02795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W67_02795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W67_02800	COG2003	Belongs to the UPF0758 family
J5W67_02820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W67_02825	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W67_02845	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W67_02905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W67_02905	COG0662	Cupin 2, conserved barrel domain protein
J5W67_02915	COG0416	fatty acid biosynthetic process
J5W67_02920	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W67_02930	COG0537	adenosine 5'-monophosphoramidase activity
J5W67_02935	COG0009	L-threonylcarbamoyladenylate synthase
J5W67_02940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W67_02945	COG0228	four-way junction DNA binding
J5W67_02965	COG1862	Preprotein translocase
J5W67_02970	COG0343	queuine tRNA-ribosyltransferase activity
J5W67_02975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W67_02985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W67_02990	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5W67_02995	COG0776	regulation of translation
J5W67_03030	COG0811	peptide transport
J5W67_03045	COG3250	beta-galactosidase activity
J5W67_03050	COG0525	valine-tRNA ligase activity
J5W67_03060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W67_03065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W67_03070	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W67_03075	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W67_03080	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W67_03085	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W67_03095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W67_03100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W67_03105	COG0089	rRNA binding
J5W67_03110	COG0088	Forms part of the polypeptide exit tunnel
J5W67_03115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W67_03120	COG0051	transcription antitermination factor activity, RNA binding
J5W67_03125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5W67_03130	COG0049	tRNA binding
J5W67_03135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W67_03140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W67_03150	COG3852	Histidine kinase
J5W67_03155	COG2204	response regulator
J5W67_03165	COG1722	exodeoxyribonuclease VII activity
J5W67_03170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W67_03185	COG0795	lipopolysaccharide-transporting ATPase activity
J5W67_03190	COG1160	GTP binding
J5W67_03195	COG0444	Belongs to the ABC transporter superfamily
J5W67_03230	COG1136	(ABC) transporter
J5W67_03230	COG0577	efflux transmembrane transporter activity
J5W67_03235	COG4774	siderophore transport
J5W67_03285	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W67_03290	COG0799	negative regulation of ribosome biogenesis
J5W67_03295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W67_03360	COG1136	(ABC) transporter
J5W67_03375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5W67_03395	COG1077	Cell shape determining protein MreB Mrl
J5W67_03400	COG1530	ribonuclease E activity
J5W67_03430	COG0848	biopolymer transport protein
J5W67_03445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W67_03460	COG0134	indole-3-glycerol-phosphate synthase activity
J5W67_03470	COG0792	nuclease activity
J5W67_03480	COG1253	flavin adenine dinucleotide binding
J5W67_03490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W67_03500	COG3119	arylsulfatase activity
J5W67_03510	COG0149	triose-phosphate isomerase activity
J5W67_03550	COG1040	competence protein
J5W67_03560	COG3956	TIGRFAM MazG family protein
J5W67_03600	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W67_03605	COG0612	Peptidase, M16
J5W67_03635	COG0673	inositol 2-dehydrogenase activity
J5W67_03640	COG3034	peptidoglycan biosynthetic process
J5W67_03660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W67_03665	COG0424	maF-like protein
J5W67_03670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W67_03690	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J5W67_03700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W67_03710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W67_03720	COG0571	ribonuclease III activity
J5W67_03735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W67_03750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W67_03755	COG0470	DNA polymerase III
J5W67_03780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W67_03795	COG2226	methyltransferase
J5W67_03815	COG2942	2-epimerase
J5W67_03925	COG0535	radical SAM domain protein
J5W67_03990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_03995	COG2255	four-way junction helicase activity
J5W67_04000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W67_04005	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W67_04010	COG1216	Glycosyl transferase, family 2
J5W67_04015	COG1215	transferase activity, transferring glycosyl groups
J5W67_04025	COG0438	transferase activity, transferring glycosyl groups
J5W67_04030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W67_04050	COG0482	sulfurtransferase activity
J5W67_04055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W67_04065	COG4974	Belongs to the 'phage' integrase family
J5W67_04085	COG1910	domain protein
J5W67_04155	COG2860	membrane
J5W67_04160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W67_04165	COG2001	Belongs to the MraZ family
J5W67_04170	COG0275	rRNA processing
J5W67_04180	COG0768	penicillin binding
J5W67_04185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W67_04190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W67_04195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W67_04200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W67_04210	COG0772	Belongs to the SEDS family
J5W67_04215	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W67_04220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W67_04225	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W67_04235	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5W67_04245	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W67_04250	COG0321	lipoyl(octanoyl) transferase activity
J5W67_04255	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W67_04260	COG0066	3-isopropylmalate dehydratase activity
J5W67_04270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_04295	COG4608	Belongs to the ABC transporter superfamily
J5W67_04305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W67_04310	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W67_04315	COG0534	Mate efflux family protein
J5W67_04335	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W67_04355	COG1137	ATPase activity
J5W67_04365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W67_04415	COG3118	belongs to the thioredoxin family
J5W67_04460	COG0583	DNA-binding transcription factor activity
J5W67_04465	COG2855	membrane
J5W67_04470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W67_04480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W67_04490	COG0602	queuosine metabolic process
J5W67_04495	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W67_04500	COG0217	transcriptional regulatory protein
J5W67_04520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W67_04525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5W67_04530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W67_04530	COG4651	solute:proton antiporter activity
J5W67_04540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W67_04545	COG4864	UPF0365 protein
J5W67_04555	COG2022	thiamine diphosphate biosynthetic process
J5W67_04585	COG0531	amino acid
J5W67_04590	COG0546	phosphoglycolate phosphatase activity
J5W67_04595	COG0628	permease
J5W67_04605	COG3250	beta-galactosidase activity
J5W67_04615	COG0191	fructose-bisphosphate aldolase activity
J5W67_04660	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W67_04670	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W67_04685	COG3209	COG3209 Rhs family protein
J5W67_04700	COG2096	Adenosyltransferase
J5W67_04710	COG2814	Major facilitator Superfamily
J5W67_04720	COG1690	Belongs to the RtcB family
J5W67_04755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W67_04760	COG3409	Peptidoglycan-binding domain 1 protein
J5W67_04760	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W67_04765	COG0656	L-ascorbic acid biosynthetic process
J5W67_04805	COG0022	dehydrogenase e1 component
J5W67_04855	COG0321	lipoyl(octanoyl) transferase activity
J5W67_04855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W67_04860	COG0497	DNA recombination
J5W67_04865	COG2217	Heavy metal translocating P-type atpase
J5W67_04875	COG0657	acetylesterase activity
J5W67_04875	COG2755	lipolytic protein G-D-S-L family
J5W67_04880	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W67_04890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W67_04895	COG1970	mechanosensitive ion channel activity
J5W67_04900	COG1785	Belongs to the alkaline phosphatase family
J5W67_04910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_04915	COG1363	Peptidase, m42
J5W67_04925	COG1592	Rubrerythrin
J5W67_04995	COG3345	alpha-galactosidase
J5W67_05020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W67_05025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W67_05035	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W67_05045	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W67_05050	COG0148	phosphopyruvate hydratase activity
J5W67_05090	COG0165	Argininosuccinate lyase
J5W67_05095	COG0659	secondary active sulfate transmembrane transporter activity
J5W67_05100	COG1733	regulation of RNA biosynthetic process
J5W67_05110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W67_05145	COG0542	response to heat
J5W67_05165	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W67_05175	COG0745	RESPONSE REGULATOR receiver
J5W67_05180	COG2205	protein histidine kinase activity
J5W67_05210	COG3250	beta-galactosidase activity
J5W67_05220	COG0084	hydrolase, TatD family'
J5W67_05260	COG0592	DNA-directed DNA polymerase activity
J5W67_05270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5W67_05275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W67_05275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W67_05285	COG0445	tRNA wobble uridine modification
J5W67_05295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_05300	COG0440	acetolactate synthase activity
J5W67_05305	COG1643	Atp-dependent helicase
J5W67_05315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W67_05330	COG0107	imidazoleglycerol-phosphate synthase activity
J5W67_05345	COG1733	regulation of RNA biosynthetic process
J5W67_05355	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W67_05355	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W67_05355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W67_05355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W67_05385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W67_05390	COG1073	alpha beta
J5W67_05395	COG1073	alpha beta
J5W67_05410	COG0535	radical SAM domain protein
J5W67_05415	COG0535	radical SAM domain protein
J5W67_05420	COG2873	o-acetylhomoserine
J5W67_05445	COG0473	3-isopropylmalate dehydrogenase activity
J5W67_05460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W67_05460	COG2755	lipolytic protein G-D-S-L family
J5W67_05465	COG1028	Short-chain dehydrogenase reductase Sdr
J5W67_05495	COG0477	Major facilitator Superfamily
J5W67_05505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W67_05510	COG0588	phosphoglycerate mutase activity
J5W67_05555	COG0745	RESPONSE REGULATOR receiver
J5W67_05560	COG0490	domain, Protein
J5W67_05560	COG0471	metal ion transport
J5W67_05595	COG1216	Glycosyl transferase, family 2
J5W67_05600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W67_05610	COG1442	glycosyl transferase family 8
J5W67_05610	COG1216	Glycosyl transferase, family 2
J5W67_05625	COG1408	metallophosphoesterase
J5W67_05640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W67_05645	COG0196	riboflavin kinase activity
J5W67_05655	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W67_05670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W67_05685	COG0546	phosphoglycolate phosphatase activity
J5W67_05695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W67_05695	COG0519	Catalyzes the synthesis of GMP from XMP
J5W67_05700	COG0517	IMP dehydrogenase activity
J5W67_05700	COG0516	GMP reductase activity
J5W67_05740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W67_05785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W67_05795	COG0557	exoribonuclease II activity
J5W67_05800	COG0826	peptidase U32
J5W67_05805	COG0285	dihydrofolate synthase activity
J5W67_05820	COG0673	inositol 2-dehydrogenase activity
J5W67_05825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W67_05830	COG0737	Belongs to the 5'-nucleotidase family
J5W67_05840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W67_05845	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W67_05860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W67_05865	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W67_05870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W67_05875	COG0200	Binds to the 23S rRNA
J5W67_05880	COG0201	protein transport
J5W67_05885	COG0563	adenylate kinase activity
J5W67_05890	COG0024	Methionine aminopeptidase
J5W67_05905	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W67_05925	COG1442	glycosyl transferase family 8
J5W67_05930	COG1216	Glycosyl transferase, family 2
J5W67_05935	COG1216	Glycosyl transferase, family 2
J5W67_05940	COG1216	Glycosyl transferase, family 2
J5W67_05945	COG0693	protein deglycase activity
J5W67_05950	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W67_05955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W67_05965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W67_05975	COG1966	Carbon starvation protein
J5W67_05985	COG3119	arylsulfatase activity
J5W67_05990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W67_05995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W67_06000	COG0195	Participates in both transcription termination and antitermination
J5W67_06005	COG0708	Exodeoxyribonuclease III
J5W67_06010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W67_06015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W67_06020	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W67_06025	COG0348	domain, Protein
J5W67_06040	COG0842	Transport permease protein
J5W67_06040	COG1716	ATPase activity
J5W67_06040	COG1131	(ABC) transporter
J5W67_06060	COG0724	RNA recognition motif
J5W67_06065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W67_06095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W67_06105	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W67_06110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W67_06125	COG1490	D-aminoacyl-tRNA deacylase activity
J5W67_06130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W67_06135	COG1053	succinate dehydrogenase
J5W67_06165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W67_06170	COG1028	Short-chain dehydrogenase reductase Sdr
J5W67_06180	COG0488	(ABC) transporter
J5W67_06190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W67_06200	COG3119	arylsulfatase activity
J5W67_06220	COG0175	sulfate reduction
J5W67_06225	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W67_06245	COG2267	carboxylic ester hydrolase activity
J5W67_06250	COG2095	MarC family integral membrane protein
J5W67_06255	COG0456	acetyltransferase
J5W67_06285	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W67_06290	COG0488	(ABC) transporter
J5W67_06300	COG0697	spore germination
J5W67_06310	COG0215	cysteine-tRNA ligase activity
J5W67_06320	COG3119	arylsulfatase activity
J5W67_06350	COG0481	GTPase activity
J5W67_06370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W67_06375	COG0085	RNA polymerase activity
J5W67_06380	COG0222	ribosome binding
J5W67_06385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W67_06390	COG0081	regulation of translation
J5W67_06395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W67_06400	COG0250	Participates in transcription elongation, termination and antitermination
J5W67_06415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W67_06425	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W67_06430	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5W67_06435	COG0740	serine-type endopeptidase activity
J5W67_06440	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W67_06455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W67_06475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W67_06540	COG2226	methyltransferase
J5W67_06545	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W67_06550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W67_06560	COG3119	arylsulfatase activity
J5W67_06565	COG0514	ATP-dependent DNA helicase (RecQ)
J5W67_06585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W67_06590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W67_06625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W67_06645	COG1858	cytochrome C peroxidase
J5W67_06650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W67_06655	COG0590	tRNA wobble adenosine to inosine editing
J5W67_06660	COG1940	carbohydrate kinase activity
J5W67_06665	COG2217	Heavy metal translocating P-type atpase
J5W67_06670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W67_06675	COG0237	dephospho-CoA kinase activity
J5W67_06705	COG1363	Peptidase, m42
J5W67_06710	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W67_06720	COG0006	proline dipeptidase activity
J5W67_06725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W67_06755	COG5002	protein histidine kinase activity
J5W67_06760	COG0745	RESPONSE REGULATOR receiver
J5W67_06765	COG0129	dihydroxy-acid dehydratase activity
J5W67_06800	COG1368	sulfuric ester hydrolase activity
J5W67_06820	COG1482	cell wall glycoprotein biosynthetic process
J5W67_06830	COG1757	Na H antiporter
J5W67_06835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W67_06840	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W67_06845	COG0505	Belongs to the CarA family
J5W67_06850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W67_06860	COG0067	glutamate synthase
J5W67_06860	COG0070	glutamate synthase
J5W67_06860	COG0069	glutamate synthase activity
J5W67_06885	COG4106	trans-aconitate 2-methyltransferase activity
J5W67_06890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_06905	COG0038	chloride channel
J5W67_06925	COG4221	oxidoreductase activity
J5W67_06945	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W67_06955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W67_06960	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W67_06970	COG1363	Peptidase, m42
J5W67_06980	COG0753	catalase activity
J5W67_06990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W67_07025	COG0517	IMP dehydrogenase activity
J5W67_07025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J5W67_07030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W67_07080	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W67_07090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W67_07100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W67_07105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W67_07110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W67_07115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W67_07160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W67_07200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W67_07225	COG0719	Fe-S assembly protein
J5W67_07230	COG0396	ATPase activity
J5W67_07235	COG0735	belongs to the Fur family
J5W67_07240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W67_07245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W67_07250	COG0802	atpase or kinase
J5W67_07255	COG1073	alpha beta
J5W67_07265	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W67_07275	COG2326	polyphosphate kinase activity
J5W67_07290	COG0742	ribosomal rna small subunit methyltransferase
J5W67_07310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W67_07325	COG1349	DNA-binding transcription factor activity
J5W67_07330	COG2326	polyphosphate kinase activity
J5W67_07350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W67_07380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W67_07420	COG3119	arylsulfatase activity
J5W67_07435	COG3119	arylsulfatase activity
J5W67_07445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W67_07445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W67_07460	COG0012	GTP binding
J5W67_07465	COG1686	Belongs to the peptidase S11 family
J5W67_07480	COG0758	DNA mediated transformation
J5W67_07495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W67_07500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W67_07505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W67_07510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W67_07530	COG0456	acetyltransferase
J5W67_07540	COG1058	Belongs to the CinA family
J5W67_07540	COG1546	Belongs to the CinA family
J5W67_07555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W67_07560	COG0552	protein localization to endoplasmic reticulum
J5W67_07565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W67_07570	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W67_07575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W67_07575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W67_07580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W67_07595	COG2814	Major facilitator Superfamily
J5W67_07605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W67_07610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W67_07620	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W67_07635	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_07660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W67_07670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W67_07675	COG1136	(ABC) transporter
J5W67_07680	COG2234	aminopeptidase activity
J5W67_07695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W67_07710	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W67_07725	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W67_07730	COG0101	tRNA pseudouridine synthase activity
J5W67_07755	COG0110	maltose O-acetyltransferase activity
J5W67_07760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W67_07765	COG1309	transcriptional regulator
J5W67_07785	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W67_07790	COG2207	Transcriptional regulator
J5W67_07800	COG0697	spore germination
J5W67_07810	COG2814	Major facilitator Superfamily
J5W67_07815	COG2311	Membrane
J5W67_07825	COG1253	flavin adenine dinucleotide binding
J5W67_07830	COG1253	flavin adenine dinucleotide binding
J5W67_07855	COG0167	dihydroorotate dehydrogenase activity
J5W67_07870	COG0519	Catalyzes the synthesis of GMP from XMP
J5W67_07875	COG3468	outer membrane autotransporter barrel domain protein
J5W67_07880	COG0076	glutamate decarboxylase activity
J5W67_07915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W67_07920	COG0562	UDP-galactopyranose mutase
J5W67_07925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W67_07945	COG0534	Mate efflux family protein
J5W67_07950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W67_07975	COG1403	HNH endonuclease
J5W67_08015	COG0556	nucleotide-excision repair
J5W67_08140	COG0443	Heat shock 70 kDa protein
J5W67_08145	COG0443	Heat shock 70 kDa protein
J5W67_08180	COG1373	ATPase (AAA superfamily
J5W67_08280	COG1131	(ABC) transporter
J5W67_08290	COG0714	Associated with various cellular activities
J5W67_08300	COG1881	PFAM PEBP family protein
J5W67_08330	COG1090	epimerase
J5W67_08340	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W67_08345	COG1119	ATPase activity
J5W67_08350	COG2186	Transcriptional regulator
J5W67_08385	COG0148	phosphopyruvate hydratase activity
J5W67_08400	COG0436	Aminotransferase
J5W67_08430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W67_08445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W67_08465	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W67_08475	COG1199	ATP-dependent helicase activity
J5W67_08485	COG1122	ATPase activity
J5W67_08510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W67_08515	COG0598	Magnesium transport protein CorA
J5W67_08520	COG0359	binds to the 23S rRNA
J5W67_08525	COG0138	bifunctional purine biosynthesis protein purh
J5W67_08530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W67_08535	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W67_08550	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W67_08560	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W67_08560	COG3409	Peptidoglycan-binding domain 1 protein
J5W67_08565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W67_08580	COG0437	4 iron, 4 sulfur cluster binding
J5W67_08605	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W67_08645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W67_08650	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W67_08655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W67_08660	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W67_08680	COG1442	glycosyl transferase family 8
J5W67_08720	COG0539	negative regulation of cytoplasmic translation
J5W67_08735	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W67_08745	COG1187	pseudouridine synthase activity
J5W67_08755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W67_08765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W67_08770	COG1393	Belongs to the ArsC family
J5W67_08775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W67_08785	COG1063	alcohol dehydrogenase
J5W67_08790	COG0242	peptide deformylase activity
J5W67_08800	COG1028	Short-chain dehydrogenase reductase Sdr
J5W67_08890	COG0351	phosphomethylpyrimidine kinase
J5W67_08900	COG0471	metal ion transport
J5W67_08930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W67_08945	COG0028	Belongs to the TPP enzyme family
J5W67_08950	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W67_08960	COG0205	6-phosphofructokinase activity
J5W67_08970	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W67_08980	COG0427	acetyl-CoA hydrolase
J5W67_08990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W67_09010	COG0346	lactoylglutathione lyase activity
J5W67_09020	COG0335	large ribosomal subunit rRNA binding
J5W67_09040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W67_09060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W67_09065	COG2755	lipolytic protein G-D-S-L family
J5W67_09065	COG0657	acetylesterase activity
J5W67_09070	COG2234	aminopeptidase activity
J5W67_09125	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W67_09135	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W67_09140	COG0546	phosphoglycolate phosphatase activity
J5W67_09145	COG1322	Protein conserved in bacteria
J5W67_09155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_09160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_09180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W67_09185	COG0504	CTP synthase activity
J5W67_09190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W67_09250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W67_09255	COG1127	ABC transporter
J5W67_09270	COG1132	(ABC) transporter
J5W67_09275	COG1132	(ABC) transporter
J5W67_09280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W67_09295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5W67_09335	COG4166	transmembrane transport
J5W67_09345	COG0601	transmembrane transport
J5W67_09350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W67_09365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5W67_09400	COG1475	DNA binding
J5W67_09455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W67_09455	COG1918	ferrous iron import across plasma membrane
J5W67_09465	COG3119	arylsulfatase activity
J5W67_09475	COG0750	zinc metalloprotease
J5W67_09495	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W67_09540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W67_09545	COG0540	Belongs to the ATCase OTCase family
J5W67_09550	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W67_09555	COG1720	tRNA m6t6A37 methyltransferase activity
J5W67_09570	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J5W67_09600	COG1538	Outer membrane efflux protein
J5W67_09605	COG0577	efflux transmembrane transporter activity
J5W67_09605	COG1136	(ABC) transporter
J5W67_09610	COG1136	(ABC) transporter
J5W67_09610	COG0577	efflux transmembrane transporter activity
J5W67_09630	COG0494	nUDIX hydrolase
J5W67_09640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5W67_09640	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J5W67_09645	COG1940	carbohydrate kinase activity
J5W67_09650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5W67_09655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W67_09660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W67_09665	COG1469	GTP cyclohydrolase I activity
J5W67_09675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W67_09680	COG0181	hydroxymethylbilane synthase activity
J5W67_09685	COG3189	MarR family transcriptional regulator
J5W67_09700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W67_09760	COG0515	serine threonine protein kinase
J5W67_09760	COG2815	serine threonine protein kinase
J5W67_09775	COG0156	8-amino-7-oxononanoate synthase activity
J5W67_09785	COG2816	NAD+ diphosphatase activity
J5W67_09790	COG0738	Major facilitator superfamily
J5W67_09795	COG0246	Mannitol dehydrogenase
J5W67_09800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W67_09815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W67_09820	COG1692	metallophosphoesterase
J5W67_09830	COG0180	Tryptophanyl-tRNA synthetase
J5W67_09845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W67_09860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W67_09880	COG0542	response to heat
J5W67_09885	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W67_09890	COG3880	PFAM UvrB UvrC protein
J5W67_09895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W67_09900	COG1121	(ABC) transporter
J5W67_09925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_09930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W67_09940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W67_09950	COG1216	Glycosyl transferase, family 2
J5W67_09965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W67_09970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W67_09985	COG3206	protein involved in exopolysaccharide biosynthesis
J5W67_09985	COG0489	protein tyrosine kinase activity
J5W67_09990	COG0438	transferase activity, transferring glycosyl groups
J5W67_09995	COG0438	transferase activity, transferring glycosyl groups
J5W67_10000	COG1216	Glycosyl transferase, family 2
J5W67_10025	COG0438	transferase activity, transferring glycosyl groups
J5W67_10030	COG1216	Glycosyl transferase, family 2
J5W67_10030	COG1442	glycosyl transferase family 8
J5W67_10035	COG0438	transferase activity, transferring glycosyl groups
J5W67_10040	COG1442	glycosyl transferase family 8
J5W67_10040	COG1216	Glycosyl transferase, family 2
J5W67_10045	COG0438	transferase activity, transferring glycosyl groups
J5W67_10050	COG1216	Glycosyl transferase, family 2
J5W67_10080	COG0534	Mate efflux family protein
J5W67_10085	COG2226	methyltransferase
J5W67_10100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W67_10105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W67_10110	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W67_10115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W67_10130	COG1115	amino acid carrier protein
J5W67_10140	COG2066	Belongs to the glutaminase family
J5W67_10145	COG0531	amino acid
J5W67_10150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W67_10165	COG0038	chloride channel
J5W67_10180	COG4112	unkown
J5W67_10190	COG1538	Outer membrane efflux protein
J5W67_10200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W67_10205	COG0339	signal peptide processing
J5W67_10210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W67_10260	COG0489	protein tyrosine kinase activity
J5W67_10265	COG0534	Mate efflux family protein
J5W67_10275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W67_10280	COG1312	Catalyzes the dehydration of D-mannonate
J5W67_10285	COG1904	glucuronate isomerase
J5W67_10290	COG0800	Aldolase
J5W67_10315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W67_10320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5W67_10350	COG1070	Carbohydrate kinase
J5W67_10365	COG0738	Major facilitator superfamily
J5W67_10395	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5W67_10415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_10420	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W67_10425	COG2132	Multicopper oxidase
J5W67_10455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W67_10460	COG4608	Belongs to the ABC transporter superfamily
J5W67_10465	COG0444	Belongs to the ABC transporter superfamily
J5W67_10470	COG4166	transmembrane transport
J5W67_10475	COG4239	(ABC) transporter, permease
J5W67_10480	COG0601	transmembrane transport
J5W67_10495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W67_10500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W67_10740	COG2304	oxidoreductase activity
J5W67_10755	COG0714	Associated with various cellular activities
J5W67_10760	COG0154	amidase activity
J5W67_10765	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W67_10795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_10800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W67_10835	COG1294	oxidase, subunit
J5W67_10840	COG1271	oxidase subunit
J5W67_10850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W67_10880	COG1528	Iron-storage protein
J5W67_10915	COG2949	membrane
J5W67_10920	COG1051	belongs to the nudix hydrolase family
J5W67_10930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W67_10940	COG0489	protein tyrosine kinase activity
J5W67_11005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W67_11005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W67_11030	COG0514	ATP-dependent DNA helicase (RecQ)
J5W67_11065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W67_11070	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W67_11075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W67_11105	COG1570	exodeoxyribonuclease VII activity
J5W67_11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W67_11140	COG2205	protein histidine kinase activity
J5W67_11155	COG0113	porphobilinogen synthase activity
J5W67_11180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W67_11180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W67_11210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W67_11215	COG0778	Nitroreductase
J5W67_11230	COG1335	isochorismatase
J5W67_11260	COG0375	protein maturation
J5W67_11265	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J5W67_11275	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W67_11305	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W67_11315	COG0281	malic enzyme
J5W67_11315	COG0280	phosphate acetyltransferase
J5W67_11325	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W67_11335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W67_11370	COG1216	Glycosyl transferase, family 2
J5W67_11375	COG1215	transferase activity, transferring glycosyl groups
J5W67_11395	COG0110	maltose O-acetyltransferase activity
J5W67_11410	COG0438	transferase activity, transferring glycosyl groups
J5W67_11440	COG1216	Glycosyl transferase, family 2
J5W67_11440	COG1442	glycosyl transferase family 8
J5W67_11445	COG1216	Glycosyl transferase, family 2
J5W67_11450	COG4464	protein tyrosine phosphatase activity
J5W67_11465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W67_11480	COG1592	Rubrerythrin
J5W67_11485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W67_11515	COG0753	catalase activity
J5W67_11530	COG1012	belongs to the aldehyde dehydrogenase family
J5W67_11535	COG3738	Protein conserved in bacteria
J5W67_11540	COG0151	Belongs to the GarS family
J5W67_11585	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W67_11590	COG0352	thiamine-phosphate diphosphorylase activity
J5W67_11605	COG1959	2 iron, 2 sulfur cluster binding
J5W67_11610	COG0629	single-stranded DNA binding
J5W67_11620	COG0811	peptide transport
J5W67_11630	COG0242	peptide deformylase activity
J5W67_11640	COG0640	Transcriptional regulator
J5W67_11715	COG0538	isocitrate dehydrogenase activity
J5W67_11735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W67_11740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W67_11745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W67_11750	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5W67_11755	COG0668	transmembrane transport
J5W67_11760	COG0724	RNA recognition motif
J5W67_11765	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W67_11765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W67_11770	COG0805	protein transport
J5W67_11775	COG1968	undecaprenyl-diphosphatase activity
J5W67_11790	COG0745	RESPONSE REGULATOR receiver
J5W67_11795	COG5002	protein histidine kinase activity
J5W67_11865	COG1408	metallophosphoesterase
J5W67_11875	COG1090	epimerase
J5W67_11895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W67_11905	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W67_11915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W67_11925	COG1454	alcohol dehydrogenase
J5W67_11935	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W67_11935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W67_11940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W67_11950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5W67_11995	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J5W67_11995	COG0037	tRNA processing
J5W67_12000	COG0460	homoserine dehydrogenase
J5W67_12005	COG0527	aspartate kinase activity
J5W67_12020	COG1741	Belongs to the pirin family
J5W67_12030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W67_12050	COG0363	glucosamine-6-phosphate deaminase activity
J5W67_12055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W67_12060	COG1837	Belongs to the UPF0109 family
J5W67_12075	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W67_12095	COG0534	Mate efflux family protein
J5W67_12115	COG0789	Transcriptional regulator
J5W67_12145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W67_12150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W67_12155	COG0789	Transcriptional regulator
J5W67_12160	COG1408	metallophosphoesterase
J5W67_12165	COG0656	L-ascorbic acid biosynthetic process
J5W67_12175	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W67_12185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5W67_12225	COG1410	methionine synthase
J5W67_12225	COG0646	methionine synthase
J5W67_12230	COG2966	Psort location CytoplasmicMembrane, score
J5W67_12235	COG3610	response to peptide
J5W67_12240	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J5W67_12245	COG0732	type I restriction modification DNA specificity domain
J5W67_12250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5W67_12280	COG1703	isobutyryl-CoA mutase activity
J5W67_12335	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W67_12340	COG0513	Belongs to the DEAD box helicase family
J5W67_12345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W67_12350	COG0418	dihydroorotase activity
J5W67_12365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W67_12410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W67_12445	COG0714	Associated with various cellular activities
J5W67_12450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W67_12455	COG1194	a g-specific adenine glycosylase
J5W67_12460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W67_12470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W67_12470	COG0574	Belongs to the PEP-utilizing enzyme family
J5W67_12475	COG0166	Belongs to the GPI family
J5W67_12485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W67_12500	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W67_12500	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W67_12540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W67_12555	COG0515	serine threonine protein kinase
J5W67_12555	COG2815	serine threonine protein kinase
J5W67_12565	COG3033	Beta-eliminating lyase
J5W67_12580	COG0072	phenylalanine-tRNA ligase activity
J5W67_12580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W67_12595	COG3059	membrane
J5W67_12605	COG0326	Molecular chaperone. Has ATPase activity
J5W67_12610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W67_12635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W67_12660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W67_12665	COG1472	Belongs to the glycosyl hydrolase 3 family
J5W67_12670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W67_12685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W67_12710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W67_12715	COG1063	alcohol dehydrogenase
J5W67_12735	COG0714	Associated with various cellular activities
J5W67_12745	COG0193	aminoacyl-tRNA hydrolase activity
J5W67_12750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W67_12770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5W67_12795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W67_12810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W67_12815	COG0512	Glutamine amidotransferase of anthranilate synthase
J5W67_12855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W67_12860	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W67_12865	COG0586	Pfam SNARE associated Golgi protein
J5W67_12935	COG1518	maintenance of DNA repeat elements
J5W67_12960	COG0423	glycine-tRNA ligase activity
J5W67_12975	COG0436	Aminotransferase
J5W67_12980	COG1522	sequence-specific DNA binding
J5W67_12985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W67_12990	COG2967	ApaG domain
J5W67_13000	COG1215	transferase activity, transferring glycosyl groups
J5W67_13010	COG1678	Uncharacterized ACR, COG1678
J5W67_13015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W67_13030	COG1131	(ABC) transporter
J5W67_13035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W67_13040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W67_13045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W67_13050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W67_13060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W67_13075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W67_13110	COG4106	trans-aconitate 2-methyltransferase activity
J5W67_13125	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W67_13150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W67_13155	COG2311	Membrane
J5W67_13185	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W67_13195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W67_13210	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W67_13215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W67_13250	COG0673	inositol 2-dehydrogenase activity
J5W67_13255	COG0339	signal peptide processing
J5W67_13265	COG0018	arginyl-trna synthetase
J5W67_13310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W67_13340	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W67_13355	COG0653	protein targeting
J5W67_13360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W67_13360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5W67_13370	COG0494	nUDIX hydrolase