locus-tag	class	description
J5W64_00010	COG3468	outer membrane autotransporter barrel domain protein
J5W64_00020	COG0842	Transport permease protein
J5W64_00025	COG0842	Transport permease protein
J5W64_00030	COG0842	Transport permease protein
J5W64_00035	COG1131	(ABC) transporter
J5W64_00045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W64_00050	COG1183	phosphatidylcholine synthase activity
J5W64_00060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W64_00085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W64_00090	COG1028	Short-chain dehydrogenase reductase Sdr
J5W64_00110	COG0156	8-amino-7-oxononanoate synthase activity
J5W64_00150	COG3209	COG3209 Rhs family protein
J5W64_00180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W64_00185	COG0124	histidyl-tRNA synthetase
J5W64_00195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W64_00200	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W64_00205	COG0298	carbon dioxide binding
J5W64_00225	COG0438	transferase activity, transferring glycosyl groups
J5W64_00230	COG0443	Heat shock 70 kDa protein
J5W64_00235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W64_00240	COG0459	protein refolding
J5W64_00285	COG0632	four-way junction helicase activity
J5W64_00295	COG0126	phosphoglycerate kinase activity
J5W64_00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W64_00315	COG2271	Major facilitator Superfamily
J5W64_00340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W64_00350	COG0037	tRNA processing
J5W64_00355	COG0254	rRNA binding
J5W64_00380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W64_00385	COG0039	L-malate dehydrogenase activity
J5W64_00405	COG0778	Nitroreductase
J5W64_00410	COG0564	pseudouridine synthase activity
J5W64_00490	COG0765	amino acid transport
J5W64_00495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W64_00520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W64_00525	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W64_00545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W64_00580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5W64_00585	COG1872	DUF167
J5W64_00590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W64_00595	COG0484	heat shock protein binding
J5W64_00600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W64_00645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W64_00650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W64_00660	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W64_00665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W64_00675	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W64_00690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W64_00705	COG1686	Belongs to the peptidase S11 family
J5W64_00710	COG0205	6-phosphofructokinase activity
J5W64_00715	COG3152	Membrane
J5W64_00720	COG0428	transporter
J5W64_00725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W64_00740	COG3977	Valine--pyruvate aminotransferase
J5W64_00745	COG1561	YicC-like family, N-terminal region
J5W64_00755	COG0471	metal ion transport
J5W64_00755	COG3273	potassium ion transport
J5W64_00760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W64_00780	COG0710	3-dehydroquinate dehydratase activity
J5W64_00805	COG0726	polysaccharide deacetylase
J5W64_00810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W64_00810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W64_00830	COG0202	RNA polymerase activity
J5W64_00835	COG0203	ribosomal protein L17
J5W64_00855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W64_00870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W64_00885	COG2885	chlorophyll binding
J5W64_00935	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W64_00965	COG0667	Aldo Keto reductase
J5W64_00970	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W64_00980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W64_00985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W64_00990	COG0134	indole-3-glycerol-phosphate synthase activity
J5W64_00995	COG0135	phosphoribosylanthranilate isomerase activity
J5W64_01005	COG0159	tryptophan synthase activity
J5W64_01020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W64_01025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W64_01050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W64_01095	COG0561	phosphatase activity
J5W64_01105	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W64_01110	COG0738	Major facilitator superfamily
J5W64_01145	COG0556	nucleotide-excision repair
J5W64_01155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W64_01160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W64_01205	COG1074	ATP-dependent DNA helicase activity
J5W64_01220	COG0697	spore germination
J5W64_01225	COG2373	Large extracellular alpha-helical protein
J5W64_01230	COG1979	alcohol dehydrogenase
J5W64_01280	COG1214	PFAM Peptidase M22, glycoprotease
J5W64_01285	COG0372	Belongs to the citrate synthase family
J5W64_01290	COG3647	Membrane
J5W64_01310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W64_01320	COG1187	pseudouridine synthase activity
J5W64_01330	COG0105	UTP biosynthetic process
J5W64_01335	COG1215	transferase activity, transferring glycosyl groups
J5W64_01340	COG0463	Glycosyl transferase, family 2
J5W64_01350	COG1459	type II secretion system
J5W64_01355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W64_01365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W64_01395	COG0728	peptidoglycan biosynthetic process
J5W64_01400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W64_01400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W64_01410	COG1649	PFAM Uncharacterised BCR, COG1649
J5W64_01415	COG1691	(AIR) carboxylase
J5W64_01420	COG1606	tRNA processing
J5W64_01425	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W64_01430	COG0142	geranyltranstransferase activity
J5W64_01445	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W64_01465	COG1007	ATP synthesis coupled electron transport
J5W64_01470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W64_01480	COG0713	ATP synthesis coupled electron transport
J5W64_01485	COG0839	Belongs to the complex I subunit 6 family
J5W64_01495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W64_01500	COG1034	ATP synthesis coupled electron transport
J5W64_01505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W64_01510	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W64_01515	COG0649	NAD binding
J5W64_01520	COG0726	polysaccharide deacetylase
J5W64_01530	COG0307	riboflavin synthase, alpha
J5W64_01550	COG1640	4-alpha-glucanotransferase
J5W64_01560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W64_01565	COG1030	water channel activity
J5W64_01570	COG0358	DNA primase activity
J5W64_01575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5W64_01580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W64_01595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W64_01600	COG0793	Belongs to the peptidase S41A family
J5W64_01605	COG0575	Belongs to the CDS family
J5W64_01610	COG1643	Atp-dependent helicase
J5W64_01630	COG0617	tRNA 3'-terminal CCA addition
J5W64_01640	COG1450	Type ii and iii secretion system protein
J5W64_01655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W64_01685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W64_01690	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W64_01700	COG0268	Binds directly to 16S ribosomal RNA
J5W64_01705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W64_01710	COG0028	Belongs to the TPP enzyme family
J5W64_01730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W64_01735	COG0495	leucyl-tRNA aminoacylation
J5W64_01755	COG1166	arginine decarboxylase activity
J5W64_01765	COG3250	beta-galactosidase activity
J5W64_01770	COG3250	beta-galactosidase activity
J5W64_01775	COG3250	beta-galactosidase activity
J5W64_01780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W64_01785	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_01790	COG1335	isochorismatase
J5W64_01800	COG1228	amidohydrolase
J5W64_01815	COG0205	6-phosphofructokinase activity
J5W64_01855	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W64_01860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W64_01875	COG3896	Chloramphenicol phosphotransferase-like protein
J5W64_01910	COG4771	TonB-dependent receptor
J5W64_01930	COG0402	S-adenosylhomocysteine deaminase activity
J5W64_01935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W64_01985	COG0442	prolyl-tRNA aminoacylation
J5W64_02025	COG0657	acetylesterase activity
J5W64_02025	COG2755	lipolytic protein G-D-S-L family
J5W64_02045	COG1971	Probably functions as a manganese efflux pump
J5W64_02065	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5W64_02090	COG0673	inositol 2-dehydrogenase activity
J5W64_02100	COG0513	Belongs to the DEAD box helicase family
J5W64_02105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W64_02110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W64_02120	COG1605	Chorismate mutase
J5W64_02120	COG0077	Prephenate dehydratase
J5W64_02125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W64_02130	COG0564	pseudouridine synthase activity
J5W64_02135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W64_02155	COG1131	(ABC) transporter
J5W64_02160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W64_02165	COG0494	nUDIX hydrolase
J5W64_02395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5W64_02395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W64_02400	COG0653	protein targeting
J5W64_02415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W64_02445	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W64_02490	COG0018	arginyl-trna synthetase
J5W64_02500	COG0339	signal peptide processing
J5W64_02505	COG0673	inositol 2-dehydrogenase activity
J5W64_02540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W64_02545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W64_02560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W64_02565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5W64_02570	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_02600	COG2311	Membrane
J5W64_02605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W64_02630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W64_02645	COG4106	trans-aconitate 2-methyltransferase activity
J5W64_02675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W64_02690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W64_02700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W64_02705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W64_02710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W64_02715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W64_02720	COG1131	(ABC) transporter
J5W64_02735	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W64_02740	COG1678	Uncharacterized ACR, COG1678
J5W64_02750	COG1215	transferase activity, transferring glycosyl groups
J5W64_02760	COG2967	ApaG domain
J5W64_02765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W64_02770	COG1522	sequence-specific DNA binding
J5W64_02775	COG0436	Aminotransferase
J5W64_02790	COG0423	glycine-tRNA ligase activity
J5W64_02815	COG1518	maintenance of DNA repeat elements
J5W64_02885	COG0586	Pfam SNARE associated Golgi protein
J5W64_02890	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W64_02895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W64_02935	COG0512	Glutamine amidotransferase of anthranilate synthase
J5W64_02940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W64_02955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W64_02995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W64_03000	COG0193	aminoacyl-tRNA hydrolase activity
J5W64_03010	COG0714	Associated with various cellular activities
J5W64_03030	COG1063	alcohol dehydrogenase
J5W64_03035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W64_03060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W64_03075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W64_03080	COG1472	Belongs to the glycosyl hydrolase 3 family
J5W64_03085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W64_03105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W64_03105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W64_03110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W64_03135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W64_03140	COG0326	Molecular chaperone. Has ATPase activity
J5W64_03150	COG3059	membrane
J5W64_03165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W64_03165	COG0072	phenylalanine-tRNA ligase activity
J5W64_03180	COG3033	Beta-eliminating lyase
J5W64_03190	COG2815	serine threonine protein kinase
J5W64_03190	COG0515	serine threonine protein kinase
J5W64_03205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W64_03245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W64_03245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W64_03260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W64_03270	COG0166	Belongs to the GPI family
J5W64_03275	COG0574	Belongs to the PEP-utilizing enzyme family
J5W64_03275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W64_03285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W64_03290	COG1194	a g-specific adenine glycosylase
J5W64_03295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W64_03300	COG0714	Associated with various cellular activities
J5W64_03335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W64_03380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W64_03395	COG0418	dihydroorotase activity
J5W64_03400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W64_03405	COG0513	Belongs to the DEAD box helicase family
J5W64_03410	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W64_03475	COG1703	isobutyryl-CoA mutase activity
J5W64_03505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5W64_03510	COG0732	type I restriction modification DNA specificity domain
J5W64_03515	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J5W64_03520	COG3610	response to peptide
J5W64_03525	COG2966	Psort location CytoplasmicMembrane, score
J5W64_03530	COG1410	methionine synthase
J5W64_03530	COG0646	methionine synthase
J5W64_03570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5W64_03580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W64_03590	COG0656	L-ascorbic acid biosynthetic process
J5W64_03595	COG1408	metallophosphoesterase
J5W64_03600	COG0789	Transcriptional regulator
J5W64_03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W64_03610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W64_03635	COG0789	Transcriptional regulator
J5W64_03655	COG0534	Mate efflux family protein
J5W64_03675	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W64_03690	COG1837	Belongs to the UPF0109 family
J5W64_03695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W64_03700	COG0363	glucosamine-6-phosphate deaminase activity
J5W64_03720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W64_03730	COG1741	Belongs to the pirin family
J5W64_03745	COG0527	aspartate kinase activity
J5W64_03755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J5W64_03755	COG0037	tRNA processing
J5W64_03800	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5W64_03810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W64_03815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W64_03815	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W64_03825	COG1454	alcohol dehydrogenase
J5W64_03835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W64_03845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W64_03855	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W64_03875	COG1090	epimerase
J5W64_03885	COG1408	metallophosphoesterase
J5W64_03955	COG5002	protein histidine kinase activity
J5W64_03960	COG0745	RESPONSE REGULATOR receiver
J5W64_03975	COG1968	undecaprenyl-diphosphatase activity
J5W64_03980	COG0805	protein transport
J5W64_03985	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W64_03985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W64_03990	COG0724	RNA recognition motif
J5W64_03995	COG0668	transmembrane transport
J5W64_04000	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5W64_04005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W64_04010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W64_04015	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W64_04035	COG0538	isocitrate dehydrogenase activity
J5W64_04110	COG0640	Transcriptional regulator
J5W64_04120	COG0242	peptide deformylase activity
J5W64_04130	COG0811	peptide transport
J5W64_04140	COG0629	single-stranded DNA binding
J5W64_04145	COG1959	2 iron, 2 sulfur cluster binding
J5W64_04160	COG0352	thiamine-phosphate diphosphorylase activity
J5W64_04165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W64_04200	COG0393	Putative heavy-metal-binding
J5W64_04210	COG0151	Belongs to the GarS family
J5W64_04215	COG3738	Protein conserved in bacteria
J5W64_04220	COG1012	belongs to the aldehyde dehydrogenase family
J5W64_04235	COG0753	catalase activity
J5W64_04265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W64_04270	COG1592	Rubrerythrin
J5W64_04285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W64_04300	COG4464	protein tyrosine phosphatase activity
J5W64_04305	COG1216	Glycosyl transferase, family 2
J5W64_04310	COG1216	Glycosyl transferase, family 2
J5W64_04310	COG1442	glycosyl transferase family 8
J5W64_04340	COG0438	transferase activity, transferring glycosyl groups
J5W64_04350	COG0110	maltose O-acetyltransferase activity
J5W64_04355	COG0463	Glycosyl transferase, family 2
J5W64_04365	COG1215	transferase activity, transferring glycosyl groups
J5W64_04370	COG1216	Glycosyl transferase, family 2
J5W64_04400	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W64_04410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W64_04420	COG0281	malic enzyme
J5W64_04420	COG0280	phosphate acetyltransferase
J5W64_04430	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W64_04465	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W64_04475	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
J5W64_04480	COG0375	protein maturation
J5W64_04510	COG1335	isochorismatase
J5W64_04520	COG0778	Nitroreductase
J5W64_04525	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W64_04555	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W64_04555	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W64_04570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5W64_04580	COG0113	porphobilinogen synthase activity
J5W64_04595	COG5002	protein histidine kinase activity
J5W64_04600	COG3290	protein histidine kinase activity
J5W64_04605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W64_04640	COG1570	exodeoxyribonuclease VII activity
J5W64_04670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W64_04675	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W64_04680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W64_04715	COG0514	ATP-dependent DNA helicase (RecQ)
J5W64_04740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W64_04740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W64_04805	COG0489	protein tyrosine kinase activity
J5W64_04815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W64_04825	COG1051	belongs to the nudix hydrolase family
J5W64_04830	COG2949	membrane
J5W64_04865	COG1528	Iron-storage protein
J5W64_04895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W64_04905	COG1271	oxidase subunit
J5W64_04910	COG1294	oxidase, subunit
J5W64_04945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_04950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_04985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W64_04990	COG0154	amidase activity
J5W64_04995	COG0714	Associated with various cellular activities
J5W64_05010	COG2304	oxidoreductase activity
J5W64_05265	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W64_05270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W64_05285	COG0601	transmembrane transport
J5W64_05290	COG4239	(ABC) transporter, permease
J5W64_05295	COG4166	transmembrane transport
J5W64_05300	COG0444	Belongs to the ABC transporter superfamily
J5W64_05305	COG4608	Belongs to the ABC transporter superfamily
J5W64_05310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W64_05340	COG2132	Multicopper oxidase
J5W64_05345	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W64_05350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_05370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5W64_05400	COG0738	Major facilitator superfamily
J5W64_05415	COG1070	Carbohydrate kinase
J5W64_05445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5W64_05450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W64_05465	COG0800	Aldolase
J5W64_05470	COG1904	glucuronate isomerase
J5W64_05475	COG1312	Catalyzes the dehydration of D-mannonate
J5W64_05480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W64_05490	COG0534	Mate efflux family protein
J5W64_05495	COG0489	protein tyrosine kinase activity
J5W64_05545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W64_05550	COG0339	signal peptide processing
J5W64_05555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W64_05565	COG1538	Outer membrane efflux protein
J5W64_05575	COG4112	unkown
J5W64_05590	COG0038	chloride channel
J5W64_05605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W64_05610	COG0531	amino acid
J5W64_05615	COG2066	Belongs to the glutaminase family
J5W64_05625	COG1115	amino acid carrier protein
J5W64_05640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W64_05645	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W64_05650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W64_05655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W64_05670	COG2226	methyltransferase
J5W64_05675	COG0534	Mate efflux family protein
J5W64_05710	COG1216	Glycosyl transferase, family 2
J5W64_05715	COG0438	transferase activity, transferring glycosyl groups
J5W64_05720	COG1216	Glycosyl transferase, family 2
J5W64_05720	COG1442	glycosyl transferase family 8
J5W64_05725	COG0438	transferase activity, transferring glycosyl groups
J5W64_05730	COG1216	Glycosyl transferase, family 2
J5W64_05730	COG1442	glycosyl transferase family 8
J5W64_05735	COG0438	transferase activity, transferring glycosyl groups
J5W64_05760	COG1216	Glycosyl transferase, family 2
J5W64_05765	COG0438	transferase activity, transferring glycosyl groups
J5W64_05770	COG0438	transferase activity, transferring glycosyl groups
J5W64_05775	COG0489	protein tyrosine kinase activity
J5W64_05775	COG3206	protein involved in exopolysaccharide biosynthesis
J5W64_05790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W64_05795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W64_05810	COG1216	Glycosyl transferase, family 2
J5W64_05820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W64_05830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W64_05840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_05865	COG1121	(ABC) transporter
J5W64_05870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W64_05875	COG3880	PFAM UvrB UvrC protein
J5W64_05880	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W64_05885	COG0542	response to heat
J5W64_05905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W64_05920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W64_05935	COG0180	Tryptophanyl-tRNA synthetase
J5W64_05945	COG1692	metallophosphoesterase
J5W64_05950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W64_05965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W64_05970	COG0246	Mannitol dehydrogenase
J5W64_05975	COG0738	Major facilitator superfamily
J5W64_05980	COG2816	NAD+ diphosphatase activity
J5W64_05995	COG0156	8-amino-7-oxononanoate synthase activity
J5W64_06010	COG0515	serine threonine protein kinase
J5W64_06010	COG2815	serine threonine protein kinase
J5W64_06070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W64_06085	COG3189	MarR family transcriptional regulator
J5W64_06090	COG0181	hydroxymethylbilane synthase activity
J5W64_06095	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W64_06105	COG1469	GTP cyclohydrolase I activity
J5W64_06110	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W64_06115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W64_06120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5W64_06125	COG1940	carbohydrate kinase activity
J5W64_06130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5W64_06130	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
J5W64_06140	COG0494	nUDIX hydrolase
J5W64_06160	COG1136	(ABC) transporter
J5W64_06160	COG0577	efflux transmembrane transporter activity
J5W64_06165	COG1136	(ABC) transporter
J5W64_06165	COG0577	efflux transmembrane transporter activity
J5W64_06170	COG1538	Outer membrane efflux protein
J5W64_06225	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J5W64_06240	COG1720	tRNA m6t6A37 methyltransferase activity
J5W64_06245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W64_06250	COG0540	Belongs to the ATCase OTCase family
J5W64_06255	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W64_06300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W64_06320	COG0750	zinc metalloprotease
J5W64_06330	COG3119	arylsulfatase activity
J5W64_06340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W64_06340	COG1918	ferrous iron import across plasma membrane
J5W64_06395	COG1475	DNA binding
J5W64_06430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5W64_06445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W64_06450	COG0601	transmembrane transport
J5W64_06495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5W64_06510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W64_06515	COG1132	(ABC) transporter
J5W64_06520	COG1132	(ABC) transporter
J5W64_06535	COG1127	ABC transporter
J5W64_06540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W64_06595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W64_06600	COG0504	CTP synthase activity
J5W64_06605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W64_06625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_06630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_06640	COG1322	Protein conserved in bacteria
J5W64_06645	COG0546	phosphoglycolate phosphatase activity
J5W64_06650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W64_06660	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W64_06715	COG2234	aminopeptidase activity
J5W64_06720	COG0657	acetylesterase activity
J5W64_06720	COG2755	lipolytic protein G-D-S-L family
J5W64_06725	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W64_06745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W64_06775	COG0346	lactoylglutathione lyase activity
J5W64_06795	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W64_06805	COG0427	acetyl-CoA hydrolase
J5W64_06815	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W64_06825	COG0205	6-phosphofructokinase activity
J5W64_06835	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W64_06840	COG0028	Belongs to the TPP enzyme family
J5W64_06855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W64_06885	COG0471	metal ion transport
J5W64_06895	COG0351	phosphomethylpyrimidine kinase
J5W64_06985	COG1028	Short-chain dehydrogenase reductase Sdr
J5W64_06995	COG0242	peptide deformylase activity
J5W64_07000	COG1063	alcohol dehydrogenase
J5W64_07010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W64_07015	COG1393	Belongs to the ArsC family
J5W64_07020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W64_07030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W64_07040	COG1187	pseudouridine synthase activity
J5W64_07050	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W64_07065	COG0539	negative regulation of cytoplasmic translation
J5W64_07110	COG1442	glycosyl transferase family 8
J5W64_07130	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W64_07135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W64_07140	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W64_07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W64_07210	COG0437	4 iron, 4 sulfur cluster binding
J5W64_07225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W64_07230	COG3409	Peptidoglycan-binding domain 1 protein
J5W64_07230	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W64_07240	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W64_07255	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W64_07260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W64_07265	COG0138	bifunctional purine biosynthesis protein purh
J5W64_07270	COG0359	binds to the 23S rRNA
J5W64_07275	COG0598	Magnesium transport protein CorA
J5W64_07280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W64_07305	COG1122	ATPase activity
J5W64_07315	COG1199	ATP-dependent helicase activity
J5W64_07325	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W64_07345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W64_07360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W64_07390	COG0436	Aminotransferase
J5W64_07405	COG0148	phosphopyruvate hydratase activity
J5W64_07440	COG2186	Transcriptional regulator
J5W64_07445	COG1119	ATPase activity
J5W64_07450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W64_07460	COG1090	epimerase
J5W64_07490	COG1881	PFAM PEBP family protein
J5W64_07500	COG0714	Associated with various cellular activities
J5W64_07510	COG1131	(ABC) transporter
J5W64_07605	COG1373	ATPase (AAA superfamily
J5W64_07640	COG0443	Heat shock 70 kDa protein
J5W64_07645	COG0443	Heat shock 70 kDa protein
J5W64_07770	COG0556	nucleotide-excision repair
J5W64_07810	COG1403	HNH endonuclease
J5W64_07835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W64_07840	COG0534	Mate efflux family protein
J5W64_07860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W64_07865	COG0562	UDP-galactopyranose mutase
J5W64_07870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W64_07905	COG0076	glutamate decarboxylase activity
J5W64_07910	COG3468	outer membrane autotransporter barrel domain protein
J5W64_07915	COG0519	Catalyzes the synthesis of GMP from XMP
J5W64_07930	COG0167	dihydroorotate dehydrogenase activity
J5W64_07955	COG1253	flavin adenine dinucleotide binding
J5W64_07960	COG1253	flavin adenine dinucleotide binding
J5W64_07970	COG2311	Membrane
J5W64_07975	COG2814	Major facilitator Superfamily
J5W64_07985	COG0697	spore germination
J5W64_07995	COG2207	Transcriptional regulator
J5W64_08000	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W64_08020	COG1309	transcriptional regulator
J5W64_08025	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W64_08030	COG0110	maltose O-acetyltransferase activity
J5W64_08055	COG0101	tRNA pseudouridine synthase activity
J5W64_08060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W64_08075	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W64_08090	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W64_08105	COG2234	aminopeptidase activity
J5W64_08110	COG1136	(ABC) transporter
J5W64_08115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W64_08125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W64_08150	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_08165	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W64_08175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W64_08180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W64_08195	COG2814	Major facilitator Superfamily
J5W64_08210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W64_08215	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W64_08215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W64_08220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W64_08225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W64_08230	COG0552	protein localization to endoplasmic reticulum
J5W64_08235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W64_08250	COG1546	Belongs to the CinA family
J5W64_08250	COG1058	Belongs to the CinA family
J5W64_08260	COG0456	acetyltransferase
J5W64_08280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W64_08285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W64_08290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W64_08295	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W64_08310	COG0758	DNA mediated transformation
J5W64_08325	COG1686	Belongs to the peptidase S11 family
J5W64_08330	COG0012	GTP binding
J5W64_08345	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W64_08345	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W64_08355	COG3119	arylsulfatase activity
J5W64_08370	COG3119	arylsulfatase activity
J5W64_08410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W64_08440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W64_08460	COG2326	polyphosphate kinase activity
J5W64_08465	COG1349	DNA-binding transcription factor activity
J5W64_08480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W64_08500	COG0742	ribosomal rna small subunit methyltransferase
J5W64_08515	COG2326	polyphosphate kinase activity
J5W64_08525	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W64_08565	COG1073	alpha beta
J5W64_08570	COG0802	atpase or kinase
J5W64_08575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W64_08580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W64_08585	COG0735	belongs to the Fur family
J5W64_08590	COG0396	ATPase activity
J5W64_08595	COG0719	Fe-S assembly protein
J5W64_08620	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W64_08660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W64_08705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W64_08710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W64_08715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W64_08720	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W64_08730	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W64_08740	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W64_08790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W64_08795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J5W64_08795	COG0517	IMP dehydrogenase activity
J5W64_08825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5W64_08830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W64_08840	COG0753	catalase activity
J5W64_08850	COG1363	Peptidase, m42
J5W64_08860	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W64_08865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W64_08875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W64_08895	COG4221	oxidoreductase activity
J5W64_08915	COG0038	chloride channel
J5W64_08930	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_08935	COG4106	trans-aconitate 2-methyltransferase activity
J5W64_08965	COG0070	glutamate synthase
J5W64_08965	COG0069	glutamate synthase activity
J5W64_08965	COG0067	glutamate synthase
J5W64_08975	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W64_08980	COG0505	Belongs to the CarA family
J5W64_08985	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W64_08990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W64_08995	COG1757	Na H antiporter
J5W64_09005	COG1482	cell wall glycoprotein biosynthetic process
J5W64_09025	COG1368	sulfuric ester hydrolase activity
J5W64_09055	COG0129	dihydroxy-acid dehydratase activity
J5W64_09060	COG0745	RESPONSE REGULATOR receiver
J5W64_09065	COG5002	protein histidine kinase activity
J5W64_09095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W64_09100	COG0006	proline dipeptidase activity
J5W64_09110	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W64_09115	COG1363	Peptidase, m42
J5W64_09145	COG0237	dephospho-CoA kinase activity
J5W64_09150	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W64_09155	COG2217	Heavy metal translocating P-type atpase
J5W64_09160	COG1940	carbohydrate kinase activity
J5W64_09165	COG0590	tRNA wobble adenosine to inosine editing
J5W64_09170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W64_09175	COG1858	cytochrome C peroxidase
J5W64_09195	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W64_09230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W64_09235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W64_09250	COG0514	ATP-dependent DNA helicase (RecQ)
J5W64_09255	COG3119	arylsulfatase activity
J5W64_09265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W64_09270	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W64_09275	COG2226	methyltransferase
J5W64_09340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W64_09360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W64_09375	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W64_09380	COG0740	serine-type endopeptidase activity
J5W64_09385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5W64_09390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W64_09400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W64_09415	COG0250	Participates in transcription elongation, termination and antitermination
J5W64_09420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W64_09425	COG0081	regulation of translation
J5W64_09430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W64_09435	COG0222	ribosome binding
J5W64_09440	COG0085	RNA polymerase activity
J5W64_09445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W64_09465	COG0481	GTPase activity
J5W64_09495	COG3119	arylsulfatase activity
J5W64_09505	COG0215	cysteine-tRNA ligase activity
J5W64_09515	COG0697	spore germination
J5W64_09525	COG0488	(ABC) transporter
J5W64_09530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W64_09560	COG0456	acetyltransferase
J5W64_09565	COG2095	MarC family integral membrane protein
J5W64_09570	COG2267	carboxylic ester hydrolase activity
J5W64_09590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W64_09595	COG0175	sulfate reduction
J5W64_09615	COG3119	arylsulfatase activity
J5W64_09625	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W64_09635	COG0488	(ABC) transporter
J5W64_09645	COG1028	Short-chain dehydrogenase reductase Sdr
J5W64_09650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W64_09680	COG1053	succinate dehydrogenase
J5W64_09685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W64_09690	COG1490	D-aminoacyl-tRNA deacylase activity
J5W64_09705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W64_09710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W64_09720	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W64_09740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W64_09745	COG0724	RNA recognition motif
J5W64_09765	COG0842	Transport permease protein
J5W64_09765	COG1131	(ABC) transporter
J5W64_09765	COG1716	ATPase activity
J5W64_09780	COG0348	domain, Protein
J5W64_09785	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W64_09790	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W64_09795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W64_09800	COG0708	Exodeoxyribonuclease III
J5W64_09805	COG0195	Participates in both transcription termination and antitermination
J5W64_09810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W64_09815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W64_09820	COG3119	arylsulfatase activity
J5W64_09830	COG1966	Carbon starvation protein
J5W64_09840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W64_09850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W64_09855	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W64_09860	COG0693	protein deglycase activity
J5W64_09865	COG1216	Glycosyl transferase, family 2
J5W64_09870	COG1216	Glycosyl transferase, family 2
J5W64_09875	COG1216	Glycosyl transferase, family 2
J5W64_09880	COG1442	glycosyl transferase family 8
J5W64_09900	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W64_09915	COG0024	Methionine aminopeptidase
J5W64_09920	COG0563	adenylate kinase activity
J5W64_09925	COG0201	protein transport
J5W64_09930	COG0200	Binds to the 23S rRNA
J5W64_09935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W64_09940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W64_09945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W64_09960	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W64_09965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W64_09975	COG0737	Belongs to the 5'-nucleotidase family
J5W64_09980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W64_09985	COG0673	inositol 2-dehydrogenase activity
J5W64_10000	COG0285	dihydrofolate synthase activity
J5W64_10005	COG0826	peptidase U32
J5W64_10010	COG0557	exoribonuclease II activity
J5W64_10020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W64_10065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W64_10100	COG0517	IMP dehydrogenase activity
J5W64_10100	COG0516	GMP reductase activity
J5W64_10105	COG0519	Catalyzes the synthesis of GMP from XMP
J5W64_10105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W64_10115	COG0546	phosphoglycolate phosphatase activity
J5W64_10130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W64_10145	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W64_10150	COG0196	riboflavin kinase activity
J5W64_10155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W64_10170	COG1408	metallophosphoesterase
J5W64_10185	COG1442	glycosyl transferase family 8
J5W64_10185	COG1216	Glycosyl transferase, family 2
J5W64_10195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W64_10200	COG1216	Glycosyl transferase, family 2
J5W64_10235	COG0490	domain, Protein
J5W64_10235	COG0471	metal ion transport
J5W64_10240	COG0745	RESPONSE REGULATOR receiver
J5W64_10285	COG0588	phosphoglycerate mutase activity
J5W64_10290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W64_10300	COG0477	Major facilitator Superfamily
J5W64_10330	COG1028	Short-chain dehydrogenase reductase Sdr
J5W64_10335	COG2755	lipolytic protein G-D-S-L family
J5W64_10335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W64_10350	COG0473	3-isopropylmalate dehydrogenase activity
J5W64_10375	COG2873	o-acetylhomoserine
J5W64_10380	COG0535	radical SAM domain protein
J5W64_10385	COG0535	radical SAM domain protein
J5W64_10400	COG1073	alpha beta
J5W64_10405	COG1073	alpha beta
J5W64_10410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W64_10435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5W64_10440	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W64_10440	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W64_10440	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W64_10440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W64_10450	COG1733	regulation of RNA biosynthetic process
J5W64_10465	COG0107	imidazoleglycerol-phosphate synthase activity
J5W64_10480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W64_10485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W64_10495	COG1643	Atp-dependent helicase
J5W64_10500	COG0440	acetolactate synthase activity
J5W64_10505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_10515	COG0445	tRNA wobble uridine modification
J5W64_10525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W64_10525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W64_10530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5W64_10540	COG0592	DNA-directed DNA polymerase activity
J5W64_10580	COG0084	hydrolase, TatD family'
J5W64_10590	COG3250	beta-galactosidase activity
J5W64_10620	COG2205	protein histidine kinase activity
J5W64_10625	COG0745	RESPONSE REGULATOR receiver
J5W64_10635	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W64_10655	COG0542	response to heat
J5W64_10690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W64_10700	COG1733	regulation of RNA biosynthetic process
J5W64_10705	COG0659	secondary active sulfate transmembrane transporter activity
J5W64_10710	COG0165	Argininosuccinate lyase
J5W64_10750	COG0148	phosphopyruvate hydratase activity
J5W64_10755	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W64_10765	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W64_10775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W64_10780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W64_10805	COG3345	alpha-galactosidase
J5W64_10875	COG1592	Rubrerythrin
J5W64_10885	COG1363	Peptidase, m42
J5W64_10890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_10900	COG1785	Belongs to the alkaline phosphatase family
J5W64_10905	COG1970	mechanosensitive ion channel activity
J5W64_10910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W64_10920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W64_10925	COG0657	acetylesterase activity
J5W64_10925	COG2755	lipolytic protein G-D-S-L family
J5W64_10935	COG2217	Heavy metal translocating P-type atpase
J5W64_10940	COG0497	DNA recombination
J5W64_10945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W64_10945	COG0321	lipoyl(octanoyl) transferase activity
J5W64_10990	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W64_10995	COG0022	dehydrogenase e1 component
J5W64_11035	COG0656	L-ascorbic acid biosynthetic process
J5W64_11040	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W64_11040	COG3409	Peptidoglycan-binding domain 1 protein
J5W64_11045	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W64_11085	COG1690	Belongs to the RtcB family
J5W64_11095	COG2814	Major facilitator Superfamily
J5W64_11105	COG2096	Adenosyltransferase
J5W64_11120	COG3209	COG3209 Rhs family protein
J5W64_11135	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W64_11145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W64_11190	COG0191	fructose-bisphosphate aldolase activity
J5W64_11200	COG3250	beta-galactosidase activity
J5W64_11210	COG0628	permease
J5W64_11215	COG0546	phosphoglycolate phosphatase activity
J5W64_11220	COG0531	amino acid
J5W64_11250	COG2022	thiamine diphosphate biosynthetic process
J5W64_11260	COG4864	UPF0365 protein
J5W64_11265	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W64_11275	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W64_11275	COG4651	solute:proton antiporter activity
J5W64_11280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5W64_11285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W64_11300	COG0217	transcriptional regulatory protein
J5W64_11305	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W64_11310	COG0602	queuosine metabolic process
J5W64_11320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W64_11330	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W64_11340	COG0583	DNA-binding transcription factor activity
J5W64_11390	COG3118	belongs to the thioredoxin family
J5W64_11410	COG0017	Asparaginyl-tRNA synthetase
J5W64_11455	COG1137	ATPase activity
J5W64_11470	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W64_11490	COG0534	Mate efflux family protein
J5W64_11495	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W64_11500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W64_11510	COG4608	Belongs to the ABC transporter superfamily
J5W64_11535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W64_11545	COG0066	3-isopropylmalate dehydratase activity
J5W64_11550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W64_11555	COG0321	lipoyl(octanoyl) transferase activity
J5W64_11560	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W64_11570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5W64_11580	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W64_11585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W64_11590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W64_11595	COG0772	Belongs to the SEDS family
J5W64_11605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W64_11610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W64_11615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W64_11620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W64_11625	COG0768	penicillin binding
J5W64_11635	COG0275	rRNA processing
J5W64_11640	COG2001	Belongs to the MraZ family
J5W64_11645	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W64_11650	COG2860	membrane
J5W64_11660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W64_11665	COG0482	sulfurtransferase activity
J5W64_11690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W64_11695	COG0438	transferase activity, transferring glycosyl groups
J5W64_11705	COG1215	transferase activity, transferring glycosyl groups
J5W64_11710	COG1216	Glycosyl transferase, family 2
J5W64_11715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W64_11720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W64_11725	COG2255	four-way junction helicase activity
J5W64_11730	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W64_11795	COG0535	radical SAM domain protein
J5W64_11900	COG2942	2-epimerase
J5W64_11920	COG2226	methyltransferase
J5W64_11935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W64_11960	COG0470	DNA polymerase III
J5W64_11965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W64_11980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W64_11995	COG0571	ribonuclease III activity
J5W64_12005	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W64_12015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W64_12025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J5W64_12045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W64_12050	COG0424	maF-like protein
J5W64_12055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W64_12075	COG3034	peptidoglycan biosynthetic process
J5W64_12080	COG0673	inositol 2-dehydrogenase activity
J5W64_12110	COG0612	Peptidase, M16
J5W64_12115	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W64_12155	COG3956	TIGRFAM MazG family protein
J5W64_12165	COG1040	competence protein
J5W64_12205	COG0149	triose-phosphate isomerase activity
J5W64_12215	COG3119	arylsulfatase activity
J5W64_12220	COG0137	argininosuccinate synthase activity
J5W64_12225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W64_12235	COG1253	flavin adenine dinucleotide binding
J5W64_12245	COG0792	nuclease activity
J5W64_12255	COG0134	indole-3-glycerol-phosphate synthase activity
J5W64_12275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W64_12290	COG0848	biopolymer transport protein
J5W64_12320	COG1530	ribonuclease E activity
J5W64_12345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5W64_12360	COG1136	(ABC) transporter
J5W64_12425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W64_12430	COG0799	negative regulation of ribosome biogenesis
J5W64_12435	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W64_12485	COG4774	siderophore transport
J5W64_12490	COG1136	(ABC) transporter
J5W64_12490	COG0577	efflux transmembrane transporter activity
J5W64_12520	COG0444	Belongs to the ABC transporter superfamily
J5W64_12525	COG1160	GTP binding
J5W64_12530	COG0795	lipopolysaccharide-transporting ATPase activity
J5W64_12545	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W64_12550	COG1722	exodeoxyribonuclease VII activity
J5W64_12560	COG2204	response regulator
J5W64_12565	COG3852	Histidine kinase
J5W64_12575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W64_12580	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W64_12585	COG0049	tRNA binding
J5W64_12590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5W64_12595	COG0051	transcription antitermination factor activity, RNA binding
J5W64_12600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W64_12605	COG0088	Forms part of the polypeptide exit tunnel
J5W64_12610	COG0089	rRNA binding
J5W64_12615	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W64_12620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W64_12630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W64_12635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W64_12640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W64_12645	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W64_12650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W64_12655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W64_12665	COG0525	valine-tRNA ligase activity
J5W64_12670	COG3250	beta-galactosidase activity
J5W64_12685	COG0811	peptide transport
J5W64_12720	COG0776	regulation of translation
J5W64_12725	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5W64_12730	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W64_12740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W64_12745	COG0343	queuine tRNA-ribosyltransferase activity
J5W64_12750	COG1862	Preprotein translocase
J5W64_12770	COG0228	four-way junction DNA binding
J5W64_12775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W64_12780	COG0009	L-threonylcarbamoyladenylate synthase
J5W64_12785	COG0537	adenosine 5'-monophosphoramidase activity
J5W64_12795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W64_12800	COG0416	fatty acid biosynthetic process
J5W64_12810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W64_12810	COG0662	Cupin 2, conserved barrel domain protein
J5W64_12870	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W64_12890	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W64_12895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W64_12915	COG2003	Belongs to the UPF0758 family
J5W64_12920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W64_12920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W64_12925	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W64_12930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W64_12935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W64_12945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W64_12950	COG0322	excinuclease ABC activity
J5W64_12955	COG0811	peptide transport
J5W64_12960	COG0848	biopolymer transport protein
J5W64_12970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W64_12980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W64_12985	COG1234	tRNA 3'-trailer cleavage
J5W64_12990	COG0706	membrane insertase activity
J5W64_12995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5W64_13000	COG0594	ribonuclease P activity
J5W64_13005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5W64_13020	COG0676	glucose-6-phosphate 1-epimerase activity
J5W64_13025	COG0259	pyridoxamine-phosphate oxidase activity
J5W64_13040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W64_13050	COG1760	l-serine dehydratase
J5W64_13055	COG0492	ferredoxin-NADP+ reductase activity
J5W64_13055	COG3118	belongs to the thioredoxin family
J5W64_13090	COG1408	metallophosphoesterase
J5W64_13100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W64_13105	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W64_13115	COG0187	DNA topoisomerase II activity
J5W64_13130	COG0826	peptidase U32
J5W64_13140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W64_13215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W64_13220	COG0581	inorganic phosphate transmembrane transporter activity
J5W64_13225	COG0573	inorganic phosphate transmembrane transporter activity
J5W64_13240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W64_13275	COG0612	Peptidase, M16
J5W64_13285	COG0233	cytoplasmic translational termination
J5W64_13290	COG0528	UMP kinase activity
J5W64_13295	COG0668	transmembrane transport
J5W64_13305	COG0450	alkyl hydroperoxide reductase
J5W64_13310	COG0733	neurotransmitter:sodium symporter activity
J5W64_13335	COG4335	DNA alkylation repair
J5W64_13340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W64_13350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W64_13360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W64_13365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W64_13380	COG0456	acetyltransferase