locus-tag	class	description
J5W77_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W77_00010	COG1131	(ABC) transporter
J5W77_00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W77_00035	COG0564	pseudouridine synthase activity
J5W77_00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W77_00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W77_00060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W77_00100	COG0673	inositol 2-dehydrogenase activity
J5W77_00120	COG2814	Major facilitator Superfamily
J5W77_00140	COG1971	Probably functions as a manganese efflux pump
J5W77_00165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W77_00190	COG0442	prolyl-tRNA aminoacylation
J5W77_00210	COG0531	amino acid
J5W77_00215	COG2066	Belongs to the glutaminase family
J5W77_00225	COG1115	amino acid carrier protein
J5W77_00235	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W77_00240	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W77_00245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W77_00250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W77_00265	COG2226	methyltransferase
J5W77_00270	COG0534	Mate efflux family protein
J5W77_00340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W77_00345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W77_00350	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_00370	COG1121	(ABC) transporter
J5W77_00375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W77_00380	COG3880	PFAM UvrB UvrC protein
J5W77_00385	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W77_00390	COG0542	response to heat
J5W77_00400	COG1054	Belongs to the UPF0176 family
J5W77_00405	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5W77_00410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W77_00425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W77_00425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W77_00435	COG0180	Tryptophanyl-tRNA synthetase
J5W77_00445	COG1692	metallophosphoesterase
J5W77_00450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W77_00465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W77_00470	COG2816	NAD+ diphosphatase activity
J5W77_00475	COG0156	8-amino-7-oxononanoate synthase activity
J5W77_00535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W77_00545	COG3189	MarR family transcriptional regulator
J5W77_00550	COG0181	hydroxymethylbilane synthase activity
J5W77_00555	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W77_00565	COG1469	GTP cyclohydrolase I activity
J5W77_00570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W77_00575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W77_00580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5W77_00585	COG1940	carbohydrate kinase activity
J5W77_00600	COG0494	nUDIX hydrolase
J5W77_00605	COG1566	PFAM secretion protein HlyD family protein
J5W77_00610	COG0577	efflux transmembrane transporter activity
J5W77_00610	COG1136	(ABC) transporter
J5W77_00615	COG0577	efflux transmembrane transporter activity
J5W77_00615	COG1136	(ABC) transporter
J5W77_00620	COG1538	Outer membrane efflux protein
J5W77_00635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W77_00645	COG1720	tRNA m6t6A37 methyltransferase activity
J5W77_00650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W77_00655	COG0540	Belongs to the ATCase OTCase family
J5W77_00660	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W77_00675	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W77_00680	COG2957	Belongs to the agmatine deiminase family
J5W77_00690	COG0750	zinc metalloprotease
J5W77_00700	COG3119	arylsulfatase activity
J5W77_00710	COG1918	ferrous iron import across plasma membrane
J5W77_00710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W77_00760	COG1475	DNA binding
J5W77_00795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5W77_00810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W77_00815	COG0601	transmembrane transport
J5W77_00860	COG0849	cell division
J5W77_00870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W77_00875	COG1132	(ABC) transporter
J5W77_00880	COG1132	(ABC) transporter
J5W77_00895	COG1127	ABC transporter
J5W77_00900	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W77_00930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5W77_00945	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W77_00950	COG0504	CTP synthase activity
J5W77_00955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W77_00980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W77_00990	COG1322	Protein conserved in bacteria
J5W77_01015	COG0546	phosphoglycolate phosphatase activity
J5W77_01020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W77_01030	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W77_01030	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W77_01035	COG3209	COG3209 Rhs family protein
J5W77_01035	COG4104	PAAR repeat-containing protein
J5W77_01050	COG3209	COG3209 Rhs family protein
J5W77_01060	COG3209	COG3209 Rhs family protein
J5W77_01105	COG2234	aminopeptidase activity
J5W77_01110	COG2755	lipolytic protein G-D-S-L family
J5W77_01110	COG0657	acetylesterase activity
J5W77_01115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W77_01135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W77_01150	COG0335	large ribosomal subunit rRNA binding
J5W77_01160	COG0346	lactoylglutathione lyase activity
J5W77_01175	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J5W77_01180	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W77_01190	COG0427	acetyl-CoA hydrolase
J5W77_01200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W77_01210	COG0205	6-phosphofructokinase activity
J5W77_01225	COG0028	Belongs to the TPP enzyme family
J5W77_01250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W77_01265	COG0471	metal ion transport
J5W77_01275	COG0351	phosphomethylpyrimidine kinase
J5W77_01330	COG1028	Short-chain dehydrogenase reductase Sdr
J5W77_01340	COG0242	peptide deformylase activity
J5W77_01345	COG1063	alcohol dehydrogenase
J5W77_01355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W77_01360	COG1393	Belongs to the ArsC family
J5W77_01365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W77_01370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W77_01380	COG1187	pseudouridine synthase activity
J5W77_01390	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W77_01405	COG0539	negative regulation of cytoplasmic translation
J5W77_01450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W77_01455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W77_01460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W77_01465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W77_01500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W77_01520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W77_01520	COG0662	Cupin 2, conserved barrel domain protein
J5W77_01530	COG0416	fatty acid biosynthetic process
J5W77_01535	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W77_01545	COG0537	adenosine 5'-monophosphoramidase activity
J5W77_01550	COG0009	L-threonylcarbamoyladenylate synthase
J5W77_01555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W77_01560	COG0228	four-way junction DNA binding
J5W77_01585	COG1862	Preprotein translocase
J5W77_01590	COG0343	queuine tRNA-ribosyltransferase activity
J5W77_01595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W77_01605	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W77_01610	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5W77_01615	COG0776	regulation of translation
J5W77_01645	COG0811	peptide transport
J5W77_01660	COG3250	beta-galactosidase activity
J5W77_01665	COG0525	valine-tRNA ligase activity
J5W77_01675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W77_01680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W77_01685	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W77_01690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W77_01695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W77_01700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W77_01710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W77_01715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W77_01720	COG0089	rRNA binding
J5W77_01725	COG0088	Forms part of the polypeptide exit tunnel
J5W77_01730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W77_01735	COG0051	transcription antitermination factor activity, RNA binding
J5W77_01740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5W77_01745	COG0049	tRNA binding
J5W77_01750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W77_01755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W77_01765	COG3852	Histidine kinase
J5W77_01770	COG2204	response regulator
J5W77_01780	COG1722	exodeoxyribonuclease VII activity
J5W77_01785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W77_01800	COG0795	lipopolysaccharide-transporting ATPase activity
J5W77_01805	COG1160	GTP binding
J5W77_01810	COG0444	Belongs to the ABC transporter superfamily
J5W77_01825	COG1136	(ABC) transporter
J5W77_01825	COG0577	efflux transmembrane transporter activity
J5W77_01835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W77_01880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W77_01885	COG0799	negative regulation of ribosome biogenesis
J5W77_01890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W77_01940	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J5W77_01955	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5W77_01965	COG4221	oxidoreductase activity
J5W77_01985	COG0038	chloride channel
J5W77_01995	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_02010	COG0076	glutamate decarboxylase activity
J5W77_02025	COG0167	dihydroorotate dehydrogenase activity
J5W77_02030	COG0352	thiamine-phosphate diphosphorylase activity
J5W77_02050	COG1253	flavin adenine dinucleotide binding
J5W77_02055	COG1253	flavin adenine dinucleotide binding
J5W77_02060	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W77_02065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W77_02070	COG0110	maltose O-acetyltransferase activity
J5W77_02095	COG0101	tRNA pseudouridine synthase activity
J5W77_02100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W77_02120	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W77_02135	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_02140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W77_02160	COG1136	(ABC) transporter
J5W77_02165	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W77_02175	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W77_02200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_02205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5W77_02210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W77_02220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W77_02225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W77_02235	COG2814	Major facilitator Superfamily
J5W77_02245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W77_02250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W77_02250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W77_02255	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W77_02260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W77_02265	COG0552	protein localization to endoplasmic reticulum
J5W77_02270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W77_02290	COG1546	Belongs to the CinA family
J5W77_02290	COG1058	Belongs to the CinA family
J5W77_02300	COG0456	acetyltransferase
J5W77_02325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W77_02330	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W77_02335	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W77_02340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W77_02355	COG0758	DNA mediated transformation
J5W77_02360	COG1686	Belongs to the peptidase S11 family
J5W77_02365	COG0012	GTP binding
J5W77_02370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5W77_02380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W77_02380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W77_02400	COG3119	arylsulfatase activity
J5W77_02425	COG2259	Doxx family
J5W77_02430	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W77_02460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W77_02480	COG2326	polyphosphate kinase activity
J5W77_02485	COG1349	DNA-binding transcription factor activity
J5W77_02510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W77_02515	COG1162	GTPase activity
J5W77_02530	COG0742	ribosomal rna small subunit methyltransferase
J5W77_02545	COG2326	polyphosphate kinase activity
J5W77_02555	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W77_02565	COG1073	alpha beta
J5W77_02570	COG0802	atpase or kinase
J5W77_02575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W77_02580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W77_02585	COG0735	belongs to the Fur family
J5W77_02590	COG0396	ATPase activity
J5W77_02595	COG0719	Fe-S assembly protein
J5W77_02615	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W77_02660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W77_02680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W77_02685	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W77_02690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W77_02695	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W77_02700	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5W77_02705	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W77_02715	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W77_02765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W77_02805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5W77_02810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W77_02815	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5W77_02825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W77_02835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W77_02840	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W77_02850	COG1363	Peptidase, m42
J5W77_02865	COG1077	Cell shape determining protein MreB Mrl
J5W77_02890	COG0848	biopolymer transport protein
J5W77_02905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W77_02920	COG0134	indole-3-glycerol-phosphate synthase activity
J5W77_02925	COG0792	nuclease activity
J5W77_02935	COG1253	flavin adenine dinucleotide binding
J5W77_02945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W77_02950	COG0137	argininosuccinate synthase activity
J5W77_02965	COG0149	triose-phosphate isomerase activity
J5W77_03060	COG3015	lipoprotein NlpE involved in copper resistance
J5W77_03085	COG1040	competence protein
J5W77_03095	COG3956	TIGRFAM MazG family protein
J5W77_03115	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W77_03125	COG0612	Peptidase, M16
J5W77_03140	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W77_03145	COG0583	DNA-binding transcription factor activity
J5W77_03170	COG0673	inositol 2-dehydrogenase activity
J5W77_03175	COG3034	peptidoglycan biosynthetic process
J5W77_03195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W77_03200	COG0424	maF-like protein
J5W77_03205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W77_03235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W77_03245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W77_03255	COG0571	ribonuclease III activity
J5W77_03265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J5W77_03355	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W77_03370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W77_03390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W77_03405	COG2226	methyltransferase
J5W77_03415	COG2076	Multidrug Resistance protein
J5W77_03485	COG2255	four-way junction helicase activity
J5W77_03490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W77_03495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W77_03500	COG1215	transferase activity, transferring glycosyl groups
J5W77_03510	COG0017	Asparaginyl-tRNA synthetase
J5W77_03520	COG3118	belongs to the thioredoxin family
J5W77_03565	COG0583	DNA-binding transcription factor activity
J5W77_03570	COG2855	membrane
J5W77_03575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W77_03585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W77_03595	COG0602	queuosine metabolic process
J5W77_03600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W77_03605	COG0217	transcriptional regulatory protein
J5W77_03610	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W77_03615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W77_03615	COG4651	solute:proton antiporter activity
J5W77_03630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W77_03635	COG4864	UPF0365 protein
J5W77_03645	COG2022	thiamine diphosphate biosynthetic process
J5W77_03650	COG0531	amino acid
J5W77_03660	COG0628	permease
J5W77_03665	COG0019	diaminopimelate decarboxylase activity
J5W77_03670	COG0191	fructose-bisphosphate aldolase activity
J5W77_03675	COG1217	gtp-binding protein TYPA
J5W77_03705	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W77_03780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W77_03785	COG0517	IMP dehydrogenase activity
J5W77_03785	COG0516	GMP reductase activity
J5W77_03790	COG0519	Catalyzes the synthesis of GMP from XMP
J5W77_03790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W77_03835	COG0546	phosphoglycolate phosphatase activity
J5W77_03860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W77_03875	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W77_03880	COG0196	riboflavin kinase activity
J5W77_03885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W77_03900	COG1408	metallophosphoesterase
J5W77_03910	COG1216	Glycosyl transferase, family 2
J5W77_03910	COG1442	glycosyl transferase family 8
J5W77_03920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W77_03925	COG1216	Glycosyl transferase, family 2
J5W77_03945	COG2755	lipolytic protein G-D-S-L family
J5W77_03945	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W77_03960	COG0471	metal ion transport
J5W77_03960	COG0490	domain, Protein
J5W77_03995	COG0588	phosphoglycerate mutase activity
J5W77_04000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W77_04010	COG0477	Major facilitator Superfamily
J5W77_04015	COG1607	acyl-coa hydrolase
J5W77_04025	COG1028	Short-chain dehydrogenase reductase Sdr
J5W77_04035	COG1525	nuclease
J5W77_04050	COG1475	DNA binding
J5W77_04055	COG3969	phosphoadenosine phosphosulfate
J5W77_04070	COG0473	3-isopropylmalate dehydrogenase activity
J5W77_04095	COG2873	o-acetylhomoserine
J5W77_04100	COG0535	radical SAM domain protein
J5W77_04105	COG0535	radical SAM domain protein
J5W77_04120	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W77_04125	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5W77_04135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5W77_04140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W77_04140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W77_04140	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W77_04140	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W77_04150	COG1733	regulation of RNA biosynthetic process
J5W77_04165	COG0107	imidazoleglycerol-phosphate synthase activity
J5W77_04170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W77_04180	COG1643	Atp-dependent helicase
J5W77_04185	COG0440	acetolactate synthase activity
J5W77_04190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W77_04200	COG0445	tRNA wobble uridine modification
J5W77_04205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W77_04205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W77_04210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5W77_04220	COG0592	DNA-directed DNA polymerase activity
J5W77_04275	COG1388	LysM domain
J5W77_04275	COG0791	NLP P60 protein
J5W77_04280	COG0084	hydrolase, TatD family'
J5W77_04290	COG3250	beta-galactosidase activity
J5W77_04305	COG2205	protein histidine kinase activity
J5W77_04310	COG0745	RESPONSE REGULATOR receiver
J5W77_04320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W77_04345	COG0542	response to heat
J5W77_04390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W77_04400	COG0659	secondary active sulfate transmembrane transporter activity
J5W77_04405	COG0165	Argininosuccinate lyase
J5W77_04420	COG0148	phosphopyruvate hydratase activity
J5W77_04425	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W77_04450	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W77_04460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W77_04465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W77_04490	COG0732	type I restriction modification DNA specificity domain
J5W77_04550	COG2985	domain, Protein
J5W77_04550	COG0490	domain, Protein
J5W77_04565	COG0471	metal ion transport
J5W77_04595	COG2194	sulfuric ester hydrolase activity
J5W77_04600	COG1592	Rubrerythrin
J5W77_04610	COG1363	Peptidase, m42
J5W77_04615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_04625	COG1785	Belongs to the alkaline phosphatase family
J5W77_04630	COG1970	mechanosensitive ion channel activity
J5W77_04635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W77_04645	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W77_04655	COG2217	Heavy metal translocating P-type atpase
J5W77_04660	COG0497	DNA recombination
J5W77_04665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W77_04665	COG0321	lipoyl(octanoyl) transferase activity
J5W77_04670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J5W77_04700	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W77_04705	COG0022	dehydrogenase e1 component
J5W77_04710	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W77_04720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W77_04725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W77_04730	COG3210	domain, Protein
J5W77_04780	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W77_04780	COG3409	Peptidoglycan-binding domain 1 protein
J5W77_04785	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W77_04815	COG1690	Belongs to the RtcB family
J5W77_04825	COG2814	Major facilitator Superfamily
J5W77_04835	COG2096	Adenosyltransferase
J5W77_04845	COG0557	exoribonuclease II activity
J5W77_04875	COG0826	peptidase U32
J5W77_04880	COG0285	dihydrofolate synthase activity
J5W77_04895	COG0673	inositol 2-dehydrogenase activity
J5W77_04900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W77_04905	COG0737	Belongs to the 5'-nucleotidase family
J5W77_04915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W77_04920	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W77_04935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W77_04940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W77_04945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W77_04950	COG0200	Binds to the 23S rRNA
J5W77_04955	COG0201	protein transport
J5W77_04960	COG0563	adenylate kinase activity
J5W77_04965	COG0024	Methionine aminopeptidase
J5W77_04980	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W77_04985	COG1442	glycosyl transferase family 8
J5W77_04995	COG1216	Glycosyl transferase, family 2
J5W77_05005	COG1216	Glycosyl transferase, family 2
J5W77_05015	COG1216	Glycosyl transferase, family 2
J5W77_05020	COG0693	protein deglycase activity
J5W77_05025	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W77_05030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W77_05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W77_05045	COG1966	Carbon starvation protein
J5W77_05060	COG3119	arylsulfatase activity
J5W77_05065	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W77_05070	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W77_05075	COG0195	Participates in both transcription termination and antitermination
J5W77_05080	COG0708	Exodeoxyribonuclease III
J5W77_05085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W77_05090	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W77_05095	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W77_05105	COG0842	Transport permease protein
J5W77_05105	COG1131	(ABC) transporter
J5W77_05105	COG1716	ATPase activity
J5W77_05125	COG0724	RNA recognition motif
J5W77_05130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W77_05150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W77_05160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W77_05165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W77_05180	COG1490	D-aminoacyl-tRNA deacylase activity
J5W77_05205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W77_05210	COG1053	succinate dehydrogenase
J5W77_05255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W77_05265	COG1137	ATPase activity
J5W77_05280	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W77_05290	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W77_05295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W77_05305	COG4608	Belongs to the ABC transporter superfamily
J5W77_05310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W77_05320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W77_05330	COG0066	3-isopropylmalate dehydratase activity
J5W77_05335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W77_05340	COG0321	lipoyl(octanoyl) transferase activity
J5W77_05345	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W77_05350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5W77_05360	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W77_05365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W77_05370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W77_05375	COG0772	Belongs to the SEDS family
J5W77_05385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W77_05390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W77_05395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W77_05400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W77_05405	COG0768	penicillin binding
J5W77_05415	COG0275	rRNA processing
J5W77_05420	COG2001	Belongs to the MraZ family
J5W77_05425	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W77_05430	COG2860	membrane
J5W77_05440	COG5290	Psort location Cytoplasmic, score
J5W77_05450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W77_05455	COG0482	sulfurtransferase activity
J5W77_05460	COG0463	Glycosyl transferase, family 2
J5W77_05460	COG1216	Glycosyl transferase, family 2
J5W77_05495	COG0438	transferase activity, transferring glycosyl groups
J5W77_05505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W77_05515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W77_05545	COG1028	Short-chain dehydrogenase reductase Sdr
J5W77_05555	COG0488	(ABC) transporter
J5W77_05565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W77_05575	COG1253	flavin adenine dinucleotide binding
J5W77_05580	COG1028	Short-chain dehydrogenase reductase Sdr
J5W77_05590	COG1073	alpha beta
J5W77_05600	COG0667	Aldo Keto reductase
J5W77_05655	COG2267	carboxylic ester hydrolase activity
J5W77_05660	COG2095	MarC family integral membrane protein
J5W77_05700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W77_05705	COG0488	(ABC) transporter
J5W77_05710	COG0697	spore germination
J5W77_05720	COG0215	cysteine-tRNA ligase activity
J5W77_05730	COG3119	arylsulfatase activity
J5W77_05740	COG0481	GTPase activity
J5W77_05755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W77_05760	COG0085	RNA polymerase activity
J5W77_05765	COG0222	ribosome binding
J5W77_05770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W77_05775	COG0081	regulation of translation
J5W77_05780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W77_05785	COG0250	Participates in transcription elongation, termination and antitermination
J5W77_05800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W77_05810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W77_05820	COG0740	serine-type endopeptidase activity
J5W77_05825	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W77_05840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W77_05860	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W77_05905	COG2226	methyltransferase
J5W77_05910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W77_05915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W77_05930	COG1902	pentaerythritol trinitrate reductase activity
J5W77_05930	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5W77_05940	COG3119	arylsulfatase activity
J5W77_05945	COG0514	ATP-dependent DNA helicase (RecQ)
J5W77_05965	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W77_05970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W77_06030	COG1858	cytochrome C peroxidase
J5W77_06035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W77_06040	COG0590	tRNA wobble adenosine to inosine editing
J5W77_06045	COG1940	carbohydrate kinase activity
J5W77_06050	COG2217	Heavy metal translocating P-type atpase
J5W77_06055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W77_06085	COG1363	Peptidase, m42
J5W77_06090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W77_06100	COG0006	proline dipeptidase activity
J5W77_06105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W77_06130	COG5002	protein histidine kinase activity
J5W77_06135	COG0745	RESPONSE REGULATOR receiver
J5W77_06140	COG0129	dihydroxy-acid dehydratase activity
J5W77_06315	COG1368	sulfuric ester hydrolase activity
J5W77_06350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W77_06355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W77_06375	COG0534	Mate efflux family protein
J5W77_06380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W77_06395	COG1876	peptidase activity
J5W77_06545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W77_06550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5W77_06555	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J5W77_06560	COG2205	protein histidine kinase activity
J5W77_06565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W77_06575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W77_06590	COG0789	Transcriptional regulator
J5W77_06640	COG0714	Associated with various cellular activities
J5W77_06645	COG2311	Membrane
J5W77_06665	COG1090	epimerase
J5W77_06675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W77_06680	COG1119	ATPase activity
J5W77_06685	COG2186	Transcriptional regulator
J5W77_06710	COG0148	phosphopyruvate hydratase activity
J5W77_06715	COG0436	Aminotransferase
J5W77_06720	COG1477	protein flavinylation
J5W77_06735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W77_06745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W77_06765	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W77_06775	COG1199	ATP-dependent helicase activity
J5W77_06780	COG1122	ATPase activity
J5W77_06805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W77_06810	COG0598	Magnesium transport protein CorA
J5W77_06815	COG0359	binds to the 23S rRNA
J5W77_06820	COG0138	bifunctional purine biosynthesis protein purh
J5W77_06825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W77_06830	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W77_06840	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W77_06845	COG3409	Peptidoglycan-binding domain 1 protein
J5W77_06845	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W77_06850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W77_06860	COG0437	4 iron, 4 sulfur cluster binding
J5W77_06880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W77_06930	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W77_06950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W77_06955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W77_06975	COG2003	Belongs to the UPF0758 family
J5W77_06980	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W77_06980	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W77_06985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W77_06990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W77_06995	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W77_07000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W77_07005	COG0322	excinuclease ABC activity
J5W77_07010	COG0811	peptide transport
J5W77_07015	COG0848	biopolymer transport protein
J5W77_07025	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W77_07030	COG0483	inositol monophosphate 1-phosphatase activity
J5W77_07035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W77_07045	COG1482	cell wall glycoprotein biosynthetic process
J5W77_07055	COG1757	Na H antiporter
J5W77_07060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W77_07065	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W77_07070	COG0505	Belongs to the CarA family
J5W77_07075	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W77_07085	COG0069	glutamate synthase activity
J5W77_07085	COG0070	glutamate synthase
J5W77_07085	COG0067	glutamate synthase
J5W77_07090	COG0706	membrane insertase activity
J5W77_07095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5W77_07105	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5W77_07120	COG0657	acetylesterase activity
J5W77_07120	COG2755	lipolytic protein G-D-S-L family
J5W77_07130	COG0676	glucose-6-phosphate 1-epimerase activity
J5W77_07135	COG0259	pyridoxamine-phosphate oxidase activity
J5W77_07150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W77_07165	COG1760	l-serine dehydratase
J5W77_07170	COG3118	belongs to the thioredoxin family
J5W77_07170	COG0492	ferredoxin-NADP+ reductase activity
J5W77_07225	COG1408	metallophosphoesterase
J5W77_07235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W77_07240	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W77_07265	COG0826	peptidase U32
J5W77_07270	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W77_07290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5W77_07310	COG2895	sulfate adenylyltransferase (ATP) activity
J5W77_07310	COG0529	Catalyzes the synthesis of activated sulfate
J5W77_07315	COG0175	sulfate reduction
J5W77_07320	COG0175	sulfate reduction
J5W77_07340	COG0581	inorganic phosphate transmembrane transporter activity
J5W77_07345	COG0573	inorganic phosphate transmembrane transporter activity
J5W77_07355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W77_07365	COG2017	converts alpha-aldose to the beta-anomer
J5W77_07380	COG0612	Peptidase, M16
J5W77_07415	COG0233	cytoplasmic translational termination
J5W77_07420	COG0528	UMP kinase activity
J5W77_07425	COG0668	transmembrane transport
J5W77_07430	COG0450	alkyl hydroperoxide reductase
J5W77_07435	COG0733	neurotransmitter:sodium symporter activity
J5W77_07450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W77_07460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W77_07465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W77_07470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W77_07495	COG0842	Transport permease protein
J5W77_07500	COG0842	Transport permease protein
J5W77_07505	COG1131	(ABC) transporter
J5W77_07515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W77_07520	COG1183	phosphatidylcholine synthase activity
J5W77_07530	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W77_07540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W77_07545	COG1028	Short-chain dehydrogenase reductase Sdr
J5W77_07565	COG0156	8-amino-7-oxononanoate synthase activity
J5W77_07585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W77_07590	COG0124	histidyl-tRNA synthetase
J5W77_07595	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W77_07600	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W77_07605	COG0298	carbon dioxide binding
J5W77_07630	COG0438	transferase activity, transferring glycosyl groups
J5W77_07635	COG0443	Heat shock 70 kDa protein
J5W77_07640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W77_07645	COG0459	protein refolding
J5W77_07695	COG0632	four-way junction helicase activity
J5W77_07705	COG0126	phosphoglycerate kinase activity
J5W77_07715	COG1082	Xylose isomerase domain protein TIM barrel
J5W77_07725	COG0863	Belongs to the N(4) N(6)-methyltransferase family
J5W77_07735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W77_07745	COG2271	Major facilitator Superfamily
J5W77_07760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W77_07770	COG0037	tRNA processing
J5W77_07775	COG0254	rRNA binding
J5W77_07815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W77_07820	COG0039	L-malate dehydrogenase activity
J5W77_07840	COG0778	Nitroreductase
J5W77_07845	COG0564	pseudouridine synthase activity
J5W77_07870	COG1126	abc transporter atp-binding protein
J5W77_07875	COG0765	amino acid transport
J5W77_07885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W77_07890	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W77_07910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W77_07940	COG1872	DUF167
J5W77_07945	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W77_07950	COG0484	heat shock protein binding
J5W77_07955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W77_07965	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W77_07980	COG0277	FAD linked oxidase domain protein
J5W77_08005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W77_08010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W77_08020	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W77_08025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W77_08030	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W77_08035	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W77_08050	COG1686	Belongs to the peptidase S11 family
J5W77_08055	COG0205	6-phosphofructokinase activity
J5W77_08065	COG0428	transporter
J5W77_08070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W77_08085	COG3977	Valine--pyruvate aminotransferase
J5W77_08090	COG1561	YicC-like family, N-terminal region
J5W77_08100	COG3273	potassium ion transport
J5W77_08100	COG0471	metal ion transport
J5W77_08105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W77_08120	COG1575	Belongs to the MenA family. Type 1 subfamily
J5W77_08155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W77_08155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W77_08175	COG0202	RNA polymerase activity
J5W77_08180	COG0203	ribosomal protein L17
J5W77_08185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W77_08195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W77_08210	COG2885	chlorophyll binding
J5W77_08265	COG0667	Aldo Keto reductase
J5W77_08270	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W77_08290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W77_08295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W77_08300	COG0134	indole-3-glycerol-phosphate synthase activity
J5W77_08305	COG0135	phosphoribosylanthranilate isomerase activity
J5W77_08310	COG0133	tryptophan synthase activity
J5W77_08315	COG0159	tryptophan synthase activity
J5W77_08330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W77_08335	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W77_08345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W77_08380	COG0561	phosphatase activity
J5W77_08385	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W77_08390	COG2223	nitrite transmembrane transporter activity
J5W77_08520	COG2314	TM2 domain
J5W77_08540	COG0515	serine threonine protein kinase
J5W77_08555	COG3177	Filamentation induced by cAMP protein fic
J5W77_08585	COG0556	nucleotide-excision repair
J5W77_08590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W77_08595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W77_08615	COG1074	ATP-dependent DNA helicase activity
J5W77_08625	COG0697	spore germination
J5W77_08635	COG1002	Type II restriction enzyme, methylase subunits
J5W77_08640	COG1061	Type III restriction enzyme res subunit
J5W77_08645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J5W77_08650	COG2373	Large extracellular alpha-helical protein
J5W77_08655	COG1979	alcohol dehydrogenase
J5W77_08665	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5W77_08690	COG0372	Belongs to the citrate synthase family
J5W77_08705	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W77_08715	COG1187	pseudouridine synthase activity
J5W77_08725	COG0105	UTP biosynthetic process
J5W77_08730	COG1215	transferase activity, transferring glycosyl groups
J5W77_08735	COG0463	Glycosyl transferase, family 2
J5W77_08745	COG1459	type II secretion system
J5W77_08750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W77_08755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W77_08760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W77_08775	COG0728	peptidoglycan biosynthetic process
J5W77_08780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W77_08780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W77_08790	COG1649	PFAM Uncharacterised BCR, COG1649
J5W77_08795	COG1691	(AIR) carboxylase
J5W77_08800	COG1606	tRNA processing
J5W77_08805	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W77_08810	COG0142	geranyltranstransferase activity
J5W77_08825	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W77_08845	COG1007	ATP synthesis coupled electron transport
J5W77_08850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W77_08860	COG0713	ATP synthesis coupled electron transport
J5W77_08865	COG0839	Belongs to the complex I subunit 6 family
J5W77_08875	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W77_08880	COG1034	ATP synthesis coupled electron transport
J5W77_08885	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W77_08890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W77_08895	COG0649	NAD binding
J5W77_08905	COG0726	polysaccharide deacetylase
J5W77_08915	COG0307	riboflavin synthase, alpha
J5W77_08920	COG2264	protein methyltransferase activity
J5W77_08925	COG3210	domain, Protein
J5W77_08930	COG1640	4-alpha-glucanotransferase
J5W77_08940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W77_08945	COG1030	water channel activity
J5W77_08950	COG0358	DNA primase activity
J5W77_08955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5W77_08960	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W77_08970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W77_08975	COG0793	Belongs to the peptidase S41A family
J5W77_08985	COG1643	Atp-dependent helicase
J5W77_09010	COG1450	Type ii and iii secretion system protein
J5W77_09025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W77_09045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W77_09050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W77_09060	COG0268	Binds directly to 16S ribosomal RNA
J5W77_09065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W77_09070	COG0028	Belongs to the TPP enzyme family
J5W77_09160	COG0688	phosphatidylethanolamine metabolic process
J5W77_09165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W77_09170	COG0495	leucyl-tRNA aminoacylation
J5W77_09175	COG3119	arylsulfatase activity
J5W77_09190	COG1166	arginine decarboxylase activity
J5W77_09200	COG3250	beta-galactosidase activity
J5W77_09205	COG3250	beta-galactosidase activity
J5W77_09210	COG3250	beta-galactosidase activity
J5W77_09215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W77_09220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_09230	COG0205	6-phosphofructokinase activity
J5W77_09340	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W77_09345	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W77_09350	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J5W77_09355	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J5W77_09365	COG4771	TonB-dependent receptor
J5W77_09385	COG0402	S-adenosylhomocysteine deaminase activity
J5W77_09390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W77_09410	COG1294	oxidase, subunit
J5W77_09415	COG1271	oxidase subunit
J5W77_09425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W77_09445	COG1846	Transcriptional regulator
J5W77_09475	COG2949	membrane
J5W77_09500	COG0514	ATP-dependent DNA helicase (RecQ)
J5W77_09515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W77_09520	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W77_09525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W77_09585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W77_09590	COG2205	protein histidine kinase activity
J5W77_09605	COG0113	porphobilinogen synthase activity
J5W77_09615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5W77_09620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J5W77_09635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W77_09660	COG4106	trans-aconitate 2-methyltransferase activity
J5W77_09675	COG3475	LICD family
J5W77_09680	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W77_09690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W77_09695	COG3475	LICD family
J5W77_09700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W77_09710	COG2166	iron-sulfur cluster assembly
J5W77_09715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W77_09725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W77_09730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W77_09735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W77_09740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W77_09745	COG1131	(ABC) transporter
J5W77_09760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W77_09775	COG1215	transferase activity, transferring glycosyl groups
J5W77_09785	COG2967	ApaG domain
J5W77_09795	COG1522	sequence-specific DNA binding
J5W77_09800	COG0436	Aminotransferase
J5W77_09815	COG0423	glycine-tRNA ligase activity
J5W77_09820	COG0656	L-ascorbic acid biosynthetic process
J5W77_09835	COG2304	oxidoreductase activity
J5W77_09850	COG0714	Associated with various cellular activities
J5W77_09855	COG0154	amidase activity
J5W77_09860	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W77_09900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W77_09910	COG2755	lipolytic protein G-D-S-L family
J5W77_09910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W77_09930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W77_09940	COG0656	L-ascorbic acid biosynthetic process
J5W77_09950	COG0667	Aldo Keto reductase
J5W77_09955	COG1408	metallophosphoesterase
J5W77_09975	COG2249	NAD(P)H dehydrogenase (quinone) activity
J5W77_09980	COG0789	Transcriptional regulator
J5W77_09995	COG0534	Mate efflux family protein
J5W77_10015	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W77_10030	COG1837	Belongs to the UPF0109 family
J5W77_10035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W77_10040	COG0363	glucosamine-6-phosphate deaminase activity
J5W77_10055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W77_10075	COG1741	Belongs to the pirin family
J5W77_10095	COG1070	Carbohydrate kinase
J5W77_10110	COG0738	Major facilitator superfamily
J5W77_10125	COG1595	DNA-templated transcription, initiation
J5W77_10140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5W77_10160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W77_10165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W77_10170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W77_10175	COG0697	spore germination
J5W77_10180	COG3586	endonuclease activity
J5W77_10190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W77_10195	COG4608	Belongs to the ABC transporter superfamily
J5W77_10200	COG0444	Belongs to the ABC transporter superfamily
J5W77_10205	COG4166	transmembrane transport
J5W77_10210	COG4239	(ABC) transporter, permease
J5W77_10215	COG0601	transmembrane transport
J5W77_10230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W77_10235	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W77_10240	COG3738	Protein conserved in bacteria
J5W77_10245	COG0151	Belongs to the GarS family
J5W77_10260	COG0811	peptide transport
J5W77_10270	COG0242	peptide deformylase activity
J5W77_10525	COG2010	Cytochrome c
J5W77_10535	COG3258	Cytochrome c
J5W77_10550	COG3274	enterobacterial common antigen metabolic process
J5W77_10570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W77_10575	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W77_10580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W77_10590	COG0668	transmembrane transport
J5W77_10595	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W77_10595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W77_10600	COG0805	protein transport
J5W77_10605	COG1968	undecaprenyl-diphosphatase activity
J5W77_10625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W77_10635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W77_10645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W77_10655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W77_10665	COG1408	metallophosphoesterase
J5W77_10690	COG4974	Belongs to the 'phage' integrase family
J5W77_10710	COG1454	alcohol dehydrogenase
J5W77_10715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W77_10725	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W77_10725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W77_10730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W77_10770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W77_10780	COG4607	ABC-type enterochelin transport system periplasmic component
J5W77_10785	COG4604	ABC transporter, ATP-binding protein
J5W77_10790	COG4605	iron ion homeostasis
J5W77_10795	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5W77_10830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W77_10830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W77_10845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W77_10850	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W77_10870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W77_10885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W77_10910	COG0519	Catalyzes the synthesis of GMP from XMP
J5W77_10910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W77_10915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W77_10955	COG0646	methionine synthase
J5W77_10955	COG1410	methionine synthase
J5W77_10960	COG2966	Psort location CytoplasmicMembrane, score
J5W77_10965	COG3610	response to peptide
J5W77_10975	COG0460	homoserine dehydrogenase
J5W77_10980	COG0527	aspartate kinase activity
J5W77_10990	COG5522	Integral membrane protein (intg_mem_TP0381)
J5W77_11000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W77_11005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W77_11010	COG1194	a g-specific adenine glycosylase
J5W77_11015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W77_11020	COG0574	Belongs to the PEP-utilizing enzyme family
J5W77_11020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W77_11025	COG0166	Belongs to the GPI family
J5W77_11035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W77_11045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W77_11045	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W77_11080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W77_11085	COG2818	Glycosylase
J5W77_11100	COG2815	serine threonine protein kinase
J5W77_11100	COG0515	serine threonine protein kinase
J5W77_11110	COG3033	Beta-eliminating lyase
J5W77_11125	COG0072	phenylalanine-tRNA ligase activity
J5W77_11125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W77_11145	COG0326	Molecular chaperone. Has ATPase activity
J5W77_11150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W77_11175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W77_11180	COG1959	2 iron, 2 sulfur cluster binding
J5W77_11195	COG0352	thiamine-phosphate diphosphorylase activity
J5W77_11200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W77_11215	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_11225	COG1703	isobutyryl-CoA mutase activity
J5W77_11245	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W77_11255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W77_11260	COG0418	dihydroorotase activity
J5W77_11275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W77_11295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W77_11325	COG0534	Mate efflux family protein
J5W77_11330	COG0489	protein tyrosine kinase activity
J5W77_11340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W77_11350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W77_11360	COG1538	Outer membrane efflux protein
J5W77_11375	COG4112	unkown
J5W77_11390	COG0038	chloride channel
J5W77_11400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W77_11405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W77_11410	COG0586	Pfam SNARE associated Golgi protein
J5W77_11865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J5W77_11865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J5W77_11865	COG0506	proline dehydrogenase activity
J5W77_11880	COG0753	catalase activity
J5W77_11890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W77_11895	COG1592	Rubrerythrin
J5W77_11900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5W77_11910	COG1674	ftsk spoiiie
J5W77_11935	COG0489	protein tyrosine kinase activity
J5W77_11945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W77_11955	COG0438	transferase activity, transferring glycosyl groups
J5W77_11965	COG0438	transferase activity, transferring glycosyl groups
J5W77_11995	COG0438	transferase activity, transferring glycosyl groups
J5W77_12005	COG0110	maltose O-acetyltransferase activity
J5W77_12015	COG1216	Glycosyl transferase, family 2
J5W77_12020	COG1216	Glycosyl transferase, family 2
J5W77_12045	COG2755	lipolytic protein G-D-S-L family
J5W77_12045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W77_12065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W77_12070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W77_12075	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W77_12080	COG0280	phosphate acetyltransferase
J5W77_12080	COG0281	malic enzyme
J5W77_12095	COG1472	Belongs to the glycosyl hydrolase 3 family
J5W77_12100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W77_12115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W77_12155	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W77_12160	COG1063	alcohol dehydrogenase
J5W77_12175	COG0714	Associated with various cellular activities
J5W77_12185	COG0193	aminoacyl-tRNA hydrolase activity
J5W77_12190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W77_12205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5W77_12225	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W77_12240	COG0375	protein maturation
J5W77_12265	COG0778	Nitroreductase
J5W77_12270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W77_12290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W77_12305	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W77_12305	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W77_12325	COG0863	Belongs to the N(4) N(6)-methyltransferase family
J5W77_12345	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W77_12350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5W77_12355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W77_12415	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W77_12420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W77_12435	COG0318	PFAM AMP-dependent synthetase and ligase
J5W77_12460	COG0339	signal peptide processing
J5W77_12475	COG0018	arginyl-trna synthetase
J5W77_12515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W77_12520	COG0653	protein targeting
J5W77_12555	COG0740	serine-type endopeptidase activity
J5W77_12745	COG0494	nUDIX hydrolase