locus-tag	class	description
J5W66_00015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W66_00015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W66_00035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W66_00040	COG0778	Nitroreductase
J5W66_00065	COG0375	protein maturation
J5W66_00080	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W66_00100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5W66_00115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W66_00130	COG0714	Associated with various cellular activities
J5W66_00145	COG1063	alcohol dehydrogenase
J5W66_00150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W66_00190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W66_00205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W66_00210	COG1472	Belongs to the glycosyl hydrolase 3 family
J5W66_00225	COG0280	phosphate acetyltransferase
J5W66_00225	COG0281	malic enzyme
J5W66_00230	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W66_00235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W66_00235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W66_00240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W66_00260	COG2755	lipolytic protein G-D-S-L family
J5W66_00260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W66_00280	COG1216	Glycosyl transferase, family 2
J5W66_00310	COG0438	transferase activity, transferring glycosyl groups
J5W66_00325	COG1216	Glycosyl transferase, family 2
J5W66_00335	COG1215	transferase activity, transferring glycosyl groups
J5W66_00340	COG2244	polysaccharide biosynthetic process
J5W66_00350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W66_00360	COG0489	protein tyrosine kinase activity
J5W66_00395	COG1674	ftsk spoiiie
J5W66_00405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5W66_00410	COG1592	Rubrerythrin
J5W66_00415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W66_00590	COG0753	catalase activity
J5W66_00605	COG1012	belongs to the aldehyde dehydrogenase family
J5W66_00640	COG1518	maintenance of DNA repeat elements
J5W66_00705	COG0586	Pfam SNARE associated Golgi protein
J5W66_00710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W66_00715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W66_00725	COG0038	chloride channel
J5W66_00740	COG4112	unkown
J5W66_00755	COG1538	Outer membrane efflux protein
J5W66_00765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W66_00770	COG0339	signal peptide processing
J5W66_00780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W66_00790	COG0489	protein tyrosine kinase activity
J5W66_00795	COG0534	Mate efflux family protein
J5W66_00825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W66_00845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W66_00860	COG0418	dihydroorotase activity
J5W66_00865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W66_00875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W66_00895	COG1703	isobutyryl-CoA mutase activity
J5W66_00920	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W66_00925	COG0352	thiamine-phosphate diphosphorylase activity
J5W66_00940	COG1959	2 iron, 2 sulfur cluster binding
J5W66_00945	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W66_00970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W66_00975	COG0326	Molecular chaperone. Has ATPase activity
J5W66_00995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W66_00995	COG0072	phenylalanine-tRNA ligase activity
J5W66_01010	COG3033	Beta-eliminating lyase
J5W66_01030	COG2818	Glycosylase
J5W66_01035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W66_01070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W66_01070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W66_01080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W66_01090	COG0166	Belongs to the GPI family
J5W66_01095	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W66_01095	COG0574	Belongs to the PEP-utilizing enzyme family
J5W66_01100	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W66_01105	COG1194	a g-specific adenine glycosylase
J5W66_01110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W66_01115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W66_01125	COG5522	Integral membrane protein (intg_mem_TP0381)
J5W66_01135	COG0527	aspartate kinase activity
J5W66_01140	COG0460	homoserine dehydrogenase
J5W66_01150	COG3610	response to peptide
J5W66_01155	COG2966	Psort location CytoplasmicMembrane, score
J5W66_01160	COG0646	methionine synthase
J5W66_01160	COG1410	methionine synthase
J5W66_01200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W66_01205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W66_01205	COG0519	Catalyzes the synthesis of GMP from XMP
J5W66_01230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W66_01245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W66_01265	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W66_01270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W66_01320	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5W66_01325	COG4605	iron ion homeostasis
J5W66_01330	COG4604	ABC transporter, ATP-binding protein
J5W66_01335	COG4607	ABC-type enterochelin transport system periplasmic component
J5W66_01345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W66_01380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W66_01385	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W66_01385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W66_01395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W66_01400	COG1454	alcohol dehydrogenase
J5W66_01420	COG4974	Belongs to the 'phage' integrase family
J5W66_01445	COG1408	metallophosphoesterase
J5W66_01455	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W66_01465	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W66_01475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W66_01485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W66_01505	COG1968	undecaprenyl-diphosphatase activity
J5W66_01510	COG0805	protein transport
J5W66_01515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W66_01515	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W66_01520	COG0668	transmembrane transport
J5W66_01530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W66_01535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W66_01540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W66_01555	COG0538	isocitrate dehydrogenase activity
J5W66_01560	COG3274	enterobacterial common antigen metabolic process
J5W66_01575	COG3258	Cytochrome c
J5W66_01585	COG2010	Cytochrome c
J5W66_01620	COG0242	peptide deformylase activity
J5W66_01630	COG0811	peptide transport
J5W66_01645	COG0151	Belongs to the GarS family
J5W66_01650	COG3738	Protein conserved in bacteria
J5W66_01655	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W66_01660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W66_01675	COG0601	transmembrane transport
J5W66_01680	COG4239	(ABC) transporter, permease
J5W66_01685	COG4166	transmembrane transport
J5W66_01690	COG0444	Belongs to the ABC transporter superfamily
J5W66_01695	COG4608	Belongs to the ABC transporter superfamily
J5W66_01700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W66_01710	COG0697	spore germination
J5W66_01715	COG2132	Multicopper oxidase
J5W66_01720	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W66_01730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W66_01750	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5W66_01770	COG1595	DNA-templated transcription, initiation
J5W66_01785	COG0738	Major facilitator superfamily
J5W66_01800	COG1070	Carbohydrate kinase
J5W66_01825	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W66_01845	COG0363	glucosamine-6-phosphate deaminase activity
J5W66_01850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W66_01855	COG1837	Belongs to the UPF0109 family
J5W66_01870	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W66_01890	COG0534	Mate efflux family protein
J5W66_01905	COG0789	Transcriptional regulator
J5W66_01910	COG2249	NAD(P)H dehydrogenase (quinone) activity
J5W66_01930	COG1408	metallophosphoesterase
J5W66_01935	COG0667	Aldo Keto reductase
J5W66_01945	COG0656	L-ascorbic acid biosynthetic process
J5W66_01955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W66_01975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W66_01975	COG2755	lipolytic protein G-D-S-L family
J5W66_01985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W66_02025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W66_02030	COG0154	amidase activity
J5W66_02035	COG0714	Associated with various cellular activities
J5W66_02050	COG2304	oxidoreductase activity
J5W66_02065	COG0656	L-ascorbic acid biosynthetic process
J5W66_02070	COG0423	glycine-tRNA ligase activity
J5W66_02085	COG0436	Aminotransferase
J5W66_02090	COG1522	sequence-specific DNA binding
J5W66_02105	COG1401	restriction endodeoxyribonuclease activity
J5W66_02105	COG1401	restriction endodeoxyribonuclease activity
J5W66_02120	COG1215	transferase activity, transferring glycosyl groups
J5W66_02135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W66_02150	COG1131	(ABC) transporter
J5W66_02155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W66_02160	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W66_02165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W66_02170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W66_02180	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W66_02185	COG2166	iron-sulfur cluster assembly
J5W66_02195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W66_02200	COG3475	LICD family
J5W66_02205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W66_02215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W66_02220	COG3475	LICD family
J5W66_02235	COG4106	trans-aconitate 2-methyltransferase activity
J5W66_02260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W66_02280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5W66_02290	COG0113	porphobilinogen synthase activity
J5W66_02305	COG2205	protein histidine kinase activity
J5W66_02310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W66_02360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W66_02365	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W66_02370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W66_02385	COG0514	ATP-dependent DNA helicase (RecQ)
J5W66_02420	COG2949	membrane
J5W66_02490	COG3015	lipoprotein NlpE involved in copper resistance
J5W66_02560	COG0305	Participates in initiation and elongation during chromosome replication
J5W66_02695	COG1846	Transcriptional regulator
J5W66_02715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W66_02725	COG1271	oxidase subunit
J5W66_02730	COG1294	oxidase, subunit
J5W66_02750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W66_02755	COG0402	S-adenosylhomocysteine deaminase activity
J5W66_02775	COG4771	TonB-dependent receptor
J5W66_02785	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J5W66_02790	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W66_02795	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W66_02845	COG0205	6-phosphofructokinase activity
J5W66_02855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_02860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W66_02865	COG3250	beta-galactosidase activity
J5W66_02870	COG3250	beta-galactosidase activity
J5W66_02875	COG3250	beta-galactosidase activity
J5W66_02885	COG1166	arginine decarboxylase activity
J5W66_02900	COG3119	arylsulfatase activity
J5W66_02905	COG0495	leucyl-tRNA aminoacylation
J5W66_02910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W66_02915	COG0688	phosphatidylethanolamine metabolic process
J5W66_02925	COG0028	Belongs to the TPP enzyme family
J5W66_02930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W66_02935	COG0268	Binds directly to 16S ribosomal RNA
J5W66_02945	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W66_02950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W66_02970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W66_02985	COG1450	Type ii and iii secretion system protein
J5W66_03010	COG1643	Atp-dependent helicase
J5W66_03020	COG0793	Belongs to the peptidase S41A family
J5W66_03025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W66_03040	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W66_03045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5W66_03050	COG0358	DNA primase activity
J5W66_03055	COG1030	water channel activity
J5W66_03060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W66_03070	COG1640	4-alpha-glucanotransferase
J5W66_03075	COG3210	domain, Protein
J5W66_03085	COG2264	protein methyltransferase activity
J5W66_03090	COG0307	riboflavin synthase, alpha
J5W66_03100	COG0726	polysaccharide deacetylase
J5W66_03110	COG0649	NAD binding
J5W66_03115	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W66_03120	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W66_03125	COG1034	ATP synthesis coupled electron transport
J5W66_03130	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W66_03140	COG0839	Belongs to the complex I subunit 6 family
J5W66_03145	COG0713	ATP synthesis coupled electron transport
J5W66_03155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W66_03160	COG1007	ATP synthesis coupled electron transport
J5W66_03180	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W66_03195	COG0142	geranyltranstransferase activity
J5W66_03200	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W66_03205	COG1606	tRNA processing
J5W66_03210	COG1691	(AIR) carboxylase
J5W66_03215	COG1649	PFAM Uncharacterised BCR, COG1649
J5W66_03225	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W66_03225	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W66_03230	COG0728	peptidoglycan biosynthetic process
J5W66_03245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W66_03250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W66_03255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W66_03260	COG1459	type II secretion system
J5W66_03270	COG0463	Glycosyl transferase, family 2
J5W66_03275	COG1215	transferase activity, transferring glycosyl groups
J5W66_03280	COG0105	UTP biosynthetic process
J5W66_03290	COG1187	pseudouridine synthase activity
J5W66_03300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W66_03315	COG0372	Belongs to the citrate synthase family
J5W66_03340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5W66_03350	COG1979	alcohol dehydrogenase
J5W66_03355	COG2373	Large extracellular alpha-helical protein
J5W66_03360	COG0697	spore germination
J5W66_03370	COG1074	ATP-dependent DNA helicase activity
J5W66_03395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W66_03400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W66_03420	COG2223	nitrite transmembrane transporter activity
J5W66_03425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W66_03430	COG0561	phosphatase activity
J5W66_03455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W66_03465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W66_03470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W66_03485	COG0159	tryptophan synthase activity
J5W66_03495	COG0135	phosphoribosylanthranilate isomerase activity
J5W66_03500	COG0134	indole-3-glycerol-phosphate synthase activity
J5W66_03505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W66_03510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W66_03525	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W66_03530	COG0667	Aldo Keto reductase
J5W66_03585	COG2885	chlorophyll binding
J5W66_03600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W66_03610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W66_03615	COG0203	ribosomal protein L17
J5W66_03620	COG0202	RNA polymerase activity
J5W66_03640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W66_03640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W66_03675	COG1575	Belongs to the MenA family. Type 1 subfamily
J5W66_03690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W66_03695	COG3273	potassium ion transport
J5W66_03695	COG0471	metal ion transport
J5W66_03705	COG1561	YicC-like family, N-terminal region
J5W66_03710	COG3977	Valine--pyruvate aminotransferase
J5W66_03725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W66_03730	COG0428	transporter
J5W66_03740	COG0205	6-phosphofructokinase activity
J5W66_03745	COG1686	Belongs to the peptidase S11 family
J5W66_03760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W66_03765	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W66_03770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W66_03775	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W66_03785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W66_03790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W66_03815	COG0277	FAD linked oxidase domain protein
J5W66_03830	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W66_03840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W66_03845	COG0484	heat shock protein binding
J5W66_03850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W66_03855	COG1872	DUF167
J5W66_03905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W66_03910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W66_03920	COG0765	amino acid transport
J5W66_03925	COG1126	abc transporter atp-binding protein
J5W66_03950	COG0564	pseudouridine synthase activity
J5W66_03955	COG0778	Nitroreductase
J5W66_03975	COG0039	L-malate dehydrogenase activity
J5W66_03980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W66_04015	COG0254	rRNA binding
J5W66_04020	COG0037	tRNA processing
J5W66_04030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W66_04045	COG2271	Major facilitator Superfamily
J5W66_04055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W66_04070	COG4991	sh3 domain protein
J5W66_04070	COG3064	Membrane
J5W66_04070	COG0515	serine threonine protein kinase
J5W66_04075	COG1082	Xylose isomerase domain protein TIM barrel
J5W66_04085	COG0126	phosphoglycerate kinase activity
J5W66_04095	COG0632	four-way junction helicase activity
J5W66_04145	COG0459	protein refolding
J5W66_04150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W66_04155	COG0443	Heat shock 70 kDa protein
J5W66_04160	COG0438	transferase activity, transferring glycosyl groups
J5W66_04185	COG0298	carbon dioxide binding
J5W66_04190	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W66_04195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W66_04200	COG0124	histidyl-tRNA synthetase
J5W66_04205	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W66_04225	COG0156	8-amino-7-oxononanoate synthase activity
J5W66_04245	COG1028	Short-chain dehydrogenase reductase Sdr
J5W66_04250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W66_04260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W66_04270	COG1183	phosphatidylcholine synthase activity
J5W66_04275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W66_04285	COG1131	(ABC) transporter
J5W66_04290	COG0842	Transport permease protein
J5W66_04295	COG0842	Transport permease protein
J5W66_04320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W66_04325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W66_04330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W66_04340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W66_04355	COG0733	neurotransmitter:sodium symporter activity
J5W66_04360	COG0450	alkyl hydroperoxide reductase
J5W66_04365	COG0668	transmembrane transport
J5W66_04370	COG0528	UMP kinase activity
J5W66_04375	COG0233	cytoplasmic translational termination
J5W66_04410	COG0612	Peptidase, M16
J5W66_04425	COG2017	converts alpha-aldose to the beta-anomer
J5W66_04435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W66_04445	COG0573	inorganic phosphate transmembrane transporter activity
J5W66_04450	COG0581	inorganic phosphate transmembrane transporter activity
J5W66_04470	COG0175	sulfate reduction
J5W66_04475	COG0175	sulfate reduction
J5W66_04480	COG2895	sulfate adenylyltransferase (ATP) activity
J5W66_04480	COG0529	Catalyzes the synthesis of activated sulfate
J5W66_04500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5W66_04520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W66_04525	COG0826	peptidase U32
J5W66_04535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5W66_04555	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W66_04560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W66_04570	COG1408	metallophosphoesterase
J5W66_04620	COG0492	ferredoxin-NADP+ reductase activity
J5W66_04620	COG3118	belongs to the thioredoxin family
J5W66_04625	COG1760	l-serine dehydratase
J5W66_04640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W66_04655	COG0259	pyridoxamine-phosphate oxidase activity
J5W66_04660	COG0676	glucose-6-phosphate 1-epimerase activity
J5W66_04670	COG0657	acetylesterase activity
J5W66_04670	COG2755	lipolytic protein G-D-S-L family
J5W66_04680	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5W66_04685	COG0594	ribonuclease P activity
J5W66_04690	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5W66_04695	COG0706	membrane insertase activity
J5W66_04700	COG0067	glutamate synthase
J5W66_04700	COG0069	glutamate synthase activity
J5W66_04700	COG0070	glutamate synthase
J5W66_04710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W66_04715	COG0505	Belongs to the CarA family
J5W66_04720	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W66_04725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W66_04730	COG1757	Na H antiporter
J5W66_04740	COG1482	cell wall glycoprotein biosynthetic process
J5W66_04750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W66_04755	COG0483	inositol monophosphate 1-phosphatase activity
J5W66_04760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W66_04770	COG0848	biopolymer transport protein
J5W66_04775	COG0811	peptide transport
J5W66_04780	COG0322	excinuclease ABC activity
J5W66_04785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W66_04790	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W66_04795	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W66_04800	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W66_04805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W66_04805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W66_04810	COG2003	Belongs to the UPF0758 family
J5W66_04830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W66_04835	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W66_04855	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W66_04905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W66_04925	COG0437	4 iron, 4 sulfur cluster binding
J5W66_04935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W66_04940	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W66_04940	COG3409	Peptidoglycan-binding domain 1 protein
J5W66_04945	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W66_04955	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W66_04960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W66_04965	COG0138	bifunctional purine biosynthesis protein purh
J5W66_04970	COG0359	binds to the 23S rRNA
J5W66_04975	COG0598	Magnesium transport protein CorA
J5W66_04980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W66_05005	COG1122	ATPase activity
J5W66_05010	COG1199	ATP-dependent helicase activity
J5W66_05020	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W66_05040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W66_05050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W66_05065	COG1477	protein flavinylation
J5W66_05070	COG0436	Aminotransferase
J5W66_05075	COG0148	phosphopyruvate hydratase activity
J5W66_05105	COG2186	Transcriptional regulator
J5W66_05110	COG1119	ATPase activity
J5W66_05115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W66_05125	COG1090	epimerase
J5W66_05145	COG2311	Membrane
J5W66_05150	COG0714	Associated with various cellular activities
J5W66_05195	COG0789	Transcriptional regulator
J5W66_05200	COG0667	Aldo Keto reductase
J5W66_05215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W66_05225	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W66_05230	COG2205	protein histidine kinase activity
J5W66_05240	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J5W66_05245	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5W66_05250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W66_05365	COG1876	peptidase activity
J5W66_05380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W66_05385	COG0534	Mate efflux family protein
J5W66_05405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W66_05410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W66_05445	COG1368	sulfuric ester hydrolase activity
J5W66_05480	COG0129	dihydroxy-acid dehydratase activity
J5W66_05485	COG0745	RESPONSE REGULATOR receiver
J5W66_05490	COG5002	protein histidine kinase activity
J5W66_05510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W66_05515	COG0006	proline dipeptidase activity
J5W66_05525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W66_05530	COG1363	Peptidase, m42
J5W66_05560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W66_05565	COG2217	Heavy metal translocating P-type atpase
J5W66_05570	COG1940	carbohydrate kinase activity
J5W66_05575	COG0590	tRNA wobble adenosine to inosine editing
J5W66_05580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W66_05585	COG1858	cytochrome C peroxidase
J5W66_05640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W66_05645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W66_05665	COG0514	ATP-dependent DNA helicase (RecQ)
J5W66_05670	COG3119	arylsulfatase activity
J5W66_05680	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5W66_05680	COG1902	pentaerythritol trinitrate reductase activity
J5W66_05695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W66_05700	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W66_05705	COG2226	methyltransferase
J5W66_05775	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W66_05795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W66_05810	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W66_05815	COG0740	serine-type endopeptidase activity
J5W66_05825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W66_05835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W66_05850	COG0250	Participates in transcription elongation, termination and antitermination
J5W66_05855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W66_05860	COG0081	regulation of translation
J5W66_05865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W66_05870	COG0222	ribosome binding
J5W66_05875	COG0085	RNA polymerase activity
J5W66_05880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W66_05895	COG0481	GTPase activity
J5W66_05905	COG3119	arylsulfatase activity
J5W66_05915	COG0215	cysteine-tRNA ligase activity
J5W66_05925	COG0697	spore germination
J5W66_05930	COG0488	(ABC) transporter
J5W66_05935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W66_05965	COG2095	MarC family integral membrane protein
J5W66_05970	COG2267	carboxylic ester hydrolase activity
J5W66_06025	COG0667	Aldo Keto reductase
J5W66_06035	COG1073	alpha beta
J5W66_06045	COG1028	Short-chain dehydrogenase reductase Sdr
J5W66_06050	COG1253	flavin adenine dinucleotide binding
J5W66_06060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W66_06070	COG0488	(ABC) transporter
J5W66_06080	COG1028	Short-chain dehydrogenase reductase Sdr
J5W66_06125	COG1053	succinate dehydrogenase
J5W66_06130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W66_06140	COG1490	D-aminoacyl-tRNA deacylase activity
J5W66_06155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W66_06160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W66_06170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W66_06190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W66_06195	COG0724	RNA recognition motif
J5W66_06215	COG1131	(ABC) transporter
J5W66_06215	COG0842	Transport permease protein
J5W66_06215	COG1716	ATPase activity
J5W66_06225	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W66_06230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W66_06235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W66_06240	COG0708	Exodeoxyribonuclease III
J5W66_06245	COG0195	Participates in both transcription termination and antitermination
J5W66_06250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W66_06255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W66_06260	COG3119	arylsulfatase activity
J5W66_06270	COG1966	Carbon starvation protein
J5W66_06280	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W66_06285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W66_06290	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W66_06300	COG1216	Glycosyl transferase, family 2
J5W66_06305	COG1216	Glycosyl transferase, family 2
J5W66_06310	COG1216	Glycosyl transferase, family 2
J5W66_06315	COG1216	Glycosyl transferase, family 2
J5W66_06320	COG1442	glycosyl transferase family 8
J5W66_06325	COG1442	glycosyl transferase family 8
J5W66_06340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W66_06355	COG0024	Methionine aminopeptidase
J5W66_06360	COG0563	adenylate kinase activity
J5W66_06365	COG0201	protein transport
J5W66_06370	COG0200	Binds to the 23S rRNA
J5W66_06375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W66_06380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W66_06385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W66_06400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W66_06405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W66_06415	COG0737	Belongs to the 5'-nucleotidase family
J5W66_06420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W66_06425	COG0673	inositol 2-dehydrogenase activity
J5W66_06440	COG0285	dihydrofolate synthase activity
J5W66_06445	COG0826	peptidase U32
J5W66_06475	COG0557	exoribonuclease II activity
J5W66_06485	COG2096	Adenosyltransferase
J5W66_06495	COG2814	Major facilitator Superfamily
J5W66_06505	COG1690	Belongs to the RtcB family
J5W66_06530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W66_06535	COG3409	Peptidoglycan-binding domain 1 protein
J5W66_06535	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W66_06590	COG3210	domain, Protein
J5W66_06595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W66_06600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W66_06610	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W66_06615	COG0022	dehydrogenase e1 component
J5W66_06620	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W66_06650	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J5W66_06655	COG0321	lipoyl(octanoyl) transferase activity
J5W66_06655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W66_06660	COG0497	DNA recombination
J5W66_06665	COG2217	Heavy metal translocating P-type atpase
J5W66_06675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W66_06685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W66_06690	COG1970	mechanosensitive ion channel activity
J5W66_06695	COG1785	Belongs to the alkaline phosphatase family
J5W66_06705	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_06710	COG1363	Peptidase, m42
J5W66_06720	COG1592	Rubrerythrin
J5W66_06725	COG2194	sulfuric ester hydrolase activity
J5W66_06750	COG0471	metal ion transport
J5W66_06765	COG2985	domain, Protein
J5W66_06765	COG0490	domain, Protein
J5W66_06835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W66_06840	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W66_06850	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W66_06860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W66_06865	COG0148	phosphopyruvate hydratase activity
J5W66_06880	COG0165	Argininosuccinate lyase
J5W66_06885	COG0659	secondary active sulfate transmembrane transporter activity
J5W66_06895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W66_06940	COG0542	response to heat
J5W66_06965	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W66_06975	COG0745	RESPONSE REGULATOR receiver
J5W66_06980	COG2205	protein histidine kinase activity
J5W66_06995	COG3250	beta-galactosidase activity
J5W66_07005	COG0084	hydrolase, TatD family'
J5W66_07010	COG0791	NLP P60 protein
J5W66_07010	COG1388	LysM domain
J5W66_07040	COG0592	DNA-directed DNA polymerase activity
J5W66_07050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5W66_07055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W66_07055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W66_07060	COG0445	tRNA wobble uridine modification
J5W66_07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W66_07075	COG0440	acetolactate synthase activity
J5W66_07080	COG1643	Atp-dependent helicase
J5W66_07090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W66_07095	COG0107	imidazoleglycerol-phosphate synthase activity
J5W66_07105	COG1733	regulation of RNA biosynthetic process
J5W66_07115	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W66_07115	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W66_07115	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W66_07115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W66_07120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5W66_07130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5W66_07135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W66_07150	COG0535	radical SAM domain protein
J5W66_07155	COG0535	radical SAM domain protein
J5W66_07160	COG2873	o-acetylhomoserine
J5W66_07185	COG0473	3-isopropylmalate dehydrogenase activity
J5W66_07195	COG3969	phosphoadenosine phosphosulfate
J5W66_07200	COG1475	DNA binding
J5W66_07210	COG1525	nuclease
J5W66_07220	COG1028	Short-chain dehydrogenase reductase Sdr
J5W66_07230	COG1607	acyl-coa hydrolase
J5W66_07235	COG0477	Major facilitator Superfamily
J5W66_07245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W66_07250	COG0588	phosphoglycerate mutase activity
J5W66_07285	COG0471	metal ion transport
J5W66_07285	COG0490	domain, Protein
J5W66_07300	COG2755	lipolytic protein G-D-S-L family
J5W66_07300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W66_07320	COG1216	Glycosyl transferase, family 2
J5W66_07325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W66_07335	COG1216	Glycosyl transferase, family 2
J5W66_07335	COG1442	glycosyl transferase family 8
J5W66_07345	COG1408	metallophosphoesterase
J5W66_07360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W66_07365	COG0196	riboflavin kinase activity
J5W66_07370	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W66_07385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W66_07410	COG0546	phosphoglycolate phosphatase activity
J5W66_07420	COG1196	nuclear chromosome segregation
J5W66_07425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W66_07425	COG0519	Catalyzes the synthesis of GMP from XMP
J5W66_07430	COG0516	GMP reductase activity
J5W66_07430	COG0517	IMP dehydrogenase activity
J5W66_07435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W66_07490	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W66_07500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W66_07530	COG1217	gtp-binding protein TYPA
J5W66_07535	COG0191	fructose-bisphosphate aldolase activity
J5W66_07540	COG0019	diaminopimelate decarboxylase activity
J5W66_07545	COG0628	permease
J5W66_07555	COG0531	amino acid
J5W66_07560	COG2022	thiamine diphosphate biosynthetic process
J5W66_07570	COG4864	UPF0365 protein
J5W66_07575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W66_07585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W66_07585	COG4651	solute:proton antiporter activity
J5W66_07590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W66_07595	COG0217	transcriptional regulatory protein
J5W66_07600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W66_07605	COG0602	queuosine metabolic process
J5W66_07615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W66_07625	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W66_07630	COG2855	membrane
J5W66_07635	COG0583	DNA-binding transcription factor activity
J5W66_07680	COG3118	belongs to the thioredoxin family
J5W66_07690	COG0017	Asparaginyl-tRNA synthetase
J5W66_07730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W66_07740	COG1733	regulation of RNA biosynthetic process
J5W66_07755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W66_07765	COG1137	ATPase activity
J5W66_07780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W66_07790	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W66_07795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W66_07805	COG4608	Belongs to the ABC transporter superfamily
J5W66_07810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W66_07820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W66_07830	COG0066	3-isopropylmalate dehydratase activity
J5W66_07835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W66_07840	COG0321	lipoyl(octanoyl) transferase activity
J5W66_07845	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W66_07850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5W66_07860	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W66_07865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W66_07870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W66_07875	COG0772	Belongs to the SEDS family
J5W66_07885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W66_07890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W66_07895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W66_07900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W66_07905	COG0768	penicillin binding
J5W66_07910	COG0768	penicillin binding
J5W66_07920	COG0275	rRNA processing
J5W66_07925	COG2001	Belongs to the MraZ family
J5W66_07930	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W66_07935	COG2860	membrane
J5W66_07945	COG5290	Psort location Cytoplasmic, score
J5W66_07955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W66_07960	COG0482	sulfurtransferase activity
J5W66_07965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W66_07975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W66_07985	COG0438	transferase activity, transferring glycosyl groups
J5W66_08010	COG0463	Glycosyl transferase, family 2
J5W66_08010	COG1216	Glycosyl transferase, family 2
J5W66_08015	COG1215	transferase activity, transferring glycosyl groups
J5W66_08020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W66_08025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W66_08030	COG2255	four-way junction helicase activity
J5W66_08090	COG2076	Multidrug Resistance protein
J5W66_08100	COG2226	methyltransferase
J5W66_08110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W66_08130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W66_08145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W66_08165	COG0571	ribonuclease III activity
J5W66_08175	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W66_08185	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W66_08215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W66_08220	COG0424	maF-like protein
J5W66_08225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W66_08245	COG3034	peptidoglycan biosynthetic process
J5W66_08250	COG0673	inositol 2-dehydrogenase activity
J5W66_08275	COG0583	DNA-binding transcription factor activity
J5W66_08280	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W66_08295	COG0612	Peptidase, M16
J5W66_08305	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W66_08325	COG3956	TIGRFAM MazG family protein
J5W66_08335	COG1040	competence protein
J5W66_08370	COG0149	triose-phosphate isomerase activity
J5W66_08385	COG0137	argininosuccinate synthase activity
J5W66_08390	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W66_08400	COG1253	flavin adenine dinucleotide binding
J5W66_08410	COG0792	nuclease activity
J5W66_08415	COG0134	indole-3-glycerol-phosphate synthase activity
J5W66_08430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W66_08445	COG0848	biopolymer transport protein
J5W66_08465	COG1530	ribonuclease E activity
J5W66_08470	COG1077	Cell shape determining protein MreB Mrl
J5W66_08485	COG1363	Peptidase, m42
J5W66_08495	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W66_08500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W66_08510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W66_08520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5W66_08525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W66_08530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5W66_08565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W66_08620	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W66_08630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W66_08635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5W66_08640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W66_08645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W66_08650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W66_08655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W66_08680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W66_08725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W66_08745	COG0719	Fe-S assembly protein
J5W66_08750	COG0396	ATPase activity
J5W66_08755	COG0735	belongs to the Fur family
J5W66_08760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W66_08765	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W66_08770	COG0802	atpase or kinase
J5W66_08785	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W66_08800	COG2326	polyphosphate kinase activity
J5W66_08815	COG0742	ribosomal rna small subunit methyltransferase
J5W66_08830	COG1162	GTPase activity
J5W66_08835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W66_08870	COG2326	polyphosphate kinase activity
J5W66_08890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W66_08920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W66_08925	COG2259	Doxx family
J5W66_08950	COG3119	arylsulfatase activity
J5W66_08965	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W66_08965	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W66_08975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5W66_08980	COG0012	GTP binding
J5W66_08985	COG1686	Belongs to the peptidase S11 family
J5W66_08990	COG0758	DNA mediated transformation
J5W66_09005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W66_09010	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W66_09015	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W66_09020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W66_09045	COG0456	acetyltransferase
J5W66_09055	COG1546	Belongs to the CinA family
J5W66_09055	COG1058	Belongs to the CinA family
J5W66_09110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W66_09115	COG0552	protein localization to endoplasmic reticulum
J5W66_09120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W66_09125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W66_09130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W66_09130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W66_09135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W66_09145	COG2814	Major facilitator Superfamily
J5W66_09155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W66_09160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W66_09170	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W66_09175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5W66_09180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_09195	COG1116	anion transmembrane transporter activity
J5W66_09205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W66_09215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W66_09220	COG1136	(ABC) transporter
J5W66_09240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W66_09245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_09260	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W66_09275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W66_09280	COG0101	tRNA pseudouridine synthase activity
J5W66_09310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W66_09315	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W66_09320	COG1253	flavin adenine dinucleotide binding
J5W66_09325	COG1253	flavin adenine dinucleotide binding
J5W66_09345	COG0352	thiamine-phosphate diphosphorylase activity
J5W66_09350	COG0167	dihydroorotate dehydrogenase activity
J5W66_09365	COG0076	glutamate decarboxylase activity
J5W66_09380	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_09390	COG0038	chloride channel
J5W66_09410	COG4221	oxidoreductase activity
J5W66_09420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5W66_09435	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J5W66_09485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W66_09490	COG0799	negative regulation of ribosome biogenesis
J5W66_09495	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W66_09540	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W66_09550	COG1136	(ABC) transporter
J5W66_09550	COG0577	efflux transmembrane transporter activity
J5W66_09565	COG0444	Belongs to the ABC transporter superfamily
J5W66_09570	COG1160	GTP binding
J5W66_09575	COG0795	lipopolysaccharide-transporting ATPase activity
J5W66_09595	COG1722	exodeoxyribonuclease VII activity
J5W66_09610	COG3852	Histidine kinase
J5W66_09625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W66_09630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W66_09635	COG0049	tRNA binding
J5W66_09640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5W66_09645	COG0051	transcription antitermination factor activity, RNA binding
J5W66_09650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W66_09655	COG0088	Forms part of the polypeptide exit tunnel
J5W66_09660	COG0089	rRNA binding
J5W66_09665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W66_09670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W66_09680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W66_09685	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W66_09690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W66_09695	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W66_09700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W66_09705	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W66_09715	COG0525	valine-tRNA ligase activity
J5W66_09720	COG3250	beta-galactosidase activity
J5W66_09735	COG0811	peptide transport
J5W66_09765	COG0776	regulation of translation
J5W66_09770	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5W66_09775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W66_09785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W66_09790	COG0343	queuine tRNA-ribosyltransferase activity
J5W66_09795	COG1862	Preprotein translocase
J5W66_09820	COG0228	four-way junction DNA binding
J5W66_09825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W66_09830	COG0009	L-threonylcarbamoyladenylate synthase
J5W66_09835	COG0537	adenosine 5'-monophosphoramidase activity
J5W66_09845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W66_09850	COG0416	fatty acid biosynthetic process
J5W66_09860	COG0662	Cupin 2, conserved barrel domain protein
J5W66_09860	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W66_09880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W66_09915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W66_09920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W66_09925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W66_09930	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W66_09975	COG0539	negative regulation of cytoplasmic translation
J5W66_09990	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W66_10000	COG1187	pseudouridine synthase activity
J5W66_10010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W66_10015	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W66_10020	COG1393	Belongs to the ArsC family
J5W66_10025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W66_10035	COG1063	alcohol dehydrogenase
J5W66_10040	COG0242	peptide deformylase activity
J5W66_10050	COG1028	Short-chain dehydrogenase reductase Sdr
J5W66_10105	COG0351	phosphomethylpyrimidine kinase
J5W66_10115	COG0471	metal ion transport
J5W66_10130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W66_10150	COG0028	Belongs to the TPP enzyme family
J5W66_10155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W66_10165	COG0205	6-phosphofructokinase activity
J5W66_10175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W66_10190	COG0427	acetyl-CoA hydrolase
J5W66_10200	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W66_10205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J5W66_10220	COG0346	lactoylglutathione lyase activity
J5W66_10230	COG0335	large ribosomal subunit rRNA binding
J5W66_10250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W66_10270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W66_10275	COG2755	lipolytic protein G-D-S-L family
J5W66_10275	COG0657	acetylesterase activity
J5W66_10280	COG2234	aminopeptidase activity
J5W66_10320	COG3209	COG3209 Rhs family protein
J5W66_10325	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W66_10335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W66_10340	COG0546	phosphoglycolate phosphatase activity
J5W66_10345	COG1322	Protein conserved in bacteria
J5W66_10375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W66_10400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W66_10405	COG0504	CTP synthase activity
J5W66_10410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W66_10425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5W66_10455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W66_10460	COG1127	ABC transporter
J5W66_10475	COG1132	(ABC) transporter
J5W66_10480	COG1132	(ABC) transporter
J5W66_10485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W66_10495	COG0849	cell division
J5W66_10545	COG0601	transmembrane transport
J5W66_10550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W66_10565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5W66_10600	COG1475	DNA binding
J5W66_10660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W66_10660	COG1918	ferrous iron import across plasma membrane
J5W66_10670	COG3119	arylsulfatase activity
J5W66_10680	COG0750	zinc metalloprotease
J5W66_10690	COG2957	Belongs to the agmatine deiminase family
J5W66_10695	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W66_10710	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W66_10715	COG0540	Belongs to the ATCase OTCase family
J5W66_10720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W66_10725	COG1720	tRNA m6t6A37 methyltransferase activity
J5W66_10735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W66_10750	COG1538	Outer membrane efflux protein
J5W66_10755	COG0577	efflux transmembrane transporter activity
J5W66_10755	COG1136	(ABC) transporter
J5W66_10760	COG0577	efflux transmembrane transporter activity
J5W66_10760	COG1136	(ABC) transporter
J5W66_10765	COG1566	PFAM secretion protein HlyD family protein
J5W66_10770	COG0494	nUDIX hydrolase
J5W66_10785	COG1940	carbohydrate kinase activity
J5W66_10790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5W66_10795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W66_10800	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W66_10805	COG1469	GTP cyclohydrolase I activity
J5W66_10815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W66_10820	COG0181	hydroxymethylbilane synthase activity
J5W66_10830	COG3189	MarR family transcriptional regulator
J5W66_10840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W66_10880	COG0515	serine threonine protein kinase
J5W66_10880	COG3266	domain, Protein
J5W66_10895	COG0156	8-amino-7-oxononanoate synthase activity
J5W66_10900	COG2816	NAD+ diphosphatase activity
J5W66_10905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W66_10980	COG1715	Restriction endonuclease
J5W66_11010	COG0515	serine threonine protein kinase
J5W66_11070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W66_11075	COG1692	metallophosphoesterase
J5W66_11085	COG0180	Tryptophanyl-tRNA synthetase
J5W66_11095	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W66_11095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W66_11110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W66_11115	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5W66_11120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5W66_11130	COG0542	response to heat
J5W66_11135	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W66_11140	COG3880	PFAM UvrB UvrC protein
J5W66_11145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W66_11150	COG1121	(ABC) transporter
J5W66_11165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_11170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W66_11175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W66_11215	COG0534	Mate efflux family protein
J5W66_11220	COG2226	methyltransferase
J5W66_11235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W66_11240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W66_11245	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W66_11250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W66_11260	COG1115	amino acid carrier protein
J5W66_11275	COG2066	Belongs to the glutaminase family
J5W66_11280	COG0531	amino acid
J5W66_11315	COG0442	prolyl-tRNA aminoacylation
J5W66_11340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W66_11365	COG1971	Probably functions as a manganese efflux pump
J5W66_11400	COG0673	inositol 2-dehydrogenase activity
J5W66_11410	COG0513	Belongs to the DEAD box helicase family
J5W66_11420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W66_11425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W66_11440	COG0564	pseudouridine synthase activity
J5W66_11445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W66_11465	COG1131	(ABC) transporter
J5W66_11470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W66_11475	COG0494	nUDIX hydrolase
J5W66_11490	COG0653	protein targeting
J5W66_11495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W66_11535	COG0018	arginyl-trna synthetase
J5W66_11545	COG0339	signal peptide processing
J5W66_11570	COG0318	PFAM AMP-dependent synthetase and ligase
J5W66_11585	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W66_11590	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W66_11640	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W66_11645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5W66_11650	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W66_11670	COG0863	Belongs to the N(4) N(6)-methyltransferase family