locus-tag	class	description
J5W54_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W54_00010	COG1131	(ABC) transporter
J5W54_00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W54_00035	COG0564	pseudouridine synthase activity
J5W54_00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W54_00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W54_00060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W54_00090	COG0673	inositol 2-dehydrogenase activity
J5W54_00110	COG2814	Major facilitator Superfamily
J5W54_00115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5W54_00130	COG1971	Probably functions as a manganese efflux pump
J5W54_00155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W54_00180	COG0442	prolyl-tRNA aminoacylation
J5W54_00230	COG0531	amino acid
J5W54_00235	COG2066	Belongs to the glutaminase family
J5W54_00250	COG1115	amino acid carrier protein
J5W54_00260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W54_00265	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W54_00270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W54_00275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W54_00290	COG2226	methyltransferase
J5W54_00295	COG0534	Mate efflux family protein
J5W54_00365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W54_00370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W54_00375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_00395	COG1121	(ABC) transporter
J5W54_00400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W54_00405	COG3880	PFAM UvrB UvrC protein
J5W54_00410	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W54_00415	COG0542	response to heat
J5W54_00430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5W54_00435	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5W54_00440	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W54_00455	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W54_00455	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W54_00465	COG0180	Tryptophanyl-tRNA synthetase
J5W54_00475	COG1692	metallophosphoesterase
J5W54_00480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W54_00550	COG0515	serine threonine protein kinase
J5W54_00585	COG1715	Restriction endonuclease
J5W54_00655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W54_00660	COG2816	NAD+ diphosphatase activity
J5W54_00665	COG0156	8-amino-7-oxononanoate synthase activity
J5W54_00680	COG0515	serine threonine protein kinase
J5W54_00680	COG3266	domain, Protein
J5W54_00725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W54_00735	COG3189	MarR family transcriptional regulator
J5W54_00745	COG0181	hydroxymethylbilane synthase activity
J5W54_00750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W54_00760	COG1469	GTP cyclohydrolase I activity
J5W54_00765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W54_00770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W54_00775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5W54_00780	COG1940	carbohydrate kinase activity
J5W54_00795	COG0494	nUDIX hydrolase
J5W54_00800	COG1566	PFAM secretion protein HlyD family protein
J5W54_00805	COG1136	(ABC) transporter
J5W54_00805	COG0577	efflux transmembrane transporter activity
J5W54_00810	COG0577	efflux transmembrane transporter activity
J5W54_00810	COG1136	(ABC) transporter
J5W54_00830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W54_00870	COG1720	tRNA m6t6A37 methyltransferase activity
J5W54_00875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W54_00880	COG0540	Belongs to the ATCase OTCase family
J5W54_00885	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W54_00900	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W54_00905	COG2957	Belongs to the agmatine deiminase family
J5W54_00915	COG0750	zinc metalloprotease
J5W54_00925	COG3119	arylsulfatase activity
J5W54_00935	COG1918	ferrous iron import across plasma membrane
J5W54_00935	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W54_00985	COG1475	DNA binding
J5W54_01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W54_01040	COG0601	transmembrane transport
J5W54_01100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W54_01105	COG1132	(ABC) transporter
J5W54_01110	COG1132	(ABC) transporter
J5W54_01125	COG1127	ABC transporter
J5W54_01130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W54_01160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5W54_01175	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W54_01180	COG0504	CTP synthase activity
J5W54_01185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W54_01210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W54_01220	COG1322	Protein conserved in bacteria
J5W54_01225	COG0546	phosphoglycolate phosphatase activity
J5W54_01230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W54_01240	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W54_01240	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W54_01245	COG4104	PAAR repeat-containing protein
J5W54_01245	COG3209	COG3209 Rhs family protein
J5W54_01260	COG3209	COG3209 Rhs family protein
J5W54_01270	COG3209	COG3209 Rhs family protein
J5W54_01315	COG2234	aminopeptidase activity
J5W54_01320	COG0657	acetylesterase activity
J5W54_01320	COG2755	lipolytic protein G-D-S-L family
J5W54_01325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W54_01345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W54_01360	COG0335	large ribosomal subunit rRNA binding
J5W54_01370	COG0346	lactoylglutathione lyase activity
J5W54_01385	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J5W54_01390	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W54_01400	COG0427	acetyl-CoA hydrolase
J5W54_01410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W54_01420	COG0205	6-phosphofructokinase activity
J5W54_01430	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W54_01435	COG0028	Belongs to the TPP enzyme family
J5W54_01455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W54_01470	COG0471	metal ion transport
J5W54_01480	COG0351	phosphomethylpyrimidine kinase
J5W54_01535	COG1028	Short-chain dehydrogenase reductase Sdr
J5W54_01545	COG0242	peptide deformylase activity
J5W54_01550	COG1063	alcohol dehydrogenase
J5W54_01560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W54_01565	COG1393	Belongs to the ArsC family
J5W54_01570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W54_01575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W54_01585	COG1187	pseudouridine synthase activity
J5W54_01595	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W54_01610	COG0539	negative regulation of cytoplasmic translation
J5W54_01655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W54_01660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W54_01665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W54_01670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W54_01705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W54_01725	COG0662	Cupin 2, conserved barrel domain protein
J5W54_01725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W54_01735	COG0416	fatty acid biosynthetic process
J5W54_01740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W54_01750	COG0537	adenosine 5'-monophosphoramidase activity
J5W54_01755	COG0009	L-threonylcarbamoyladenylate synthase
J5W54_01760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W54_01765	COG0228	four-way junction DNA binding
J5W54_01785	COG1862	Preprotein translocase
J5W54_01790	COG0343	queuine tRNA-ribosyltransferase activity
J5W54_01795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W54_01805	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W54_01810	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5W54_01815	COG0776	regulation of translation
J5W54_01845	COG0811	peptide transport
J5W54_01860	COG3250	beta-galactosidase activity
J5W54_01865	COG0525	valine-tRNA ligase activity
J5W54_01875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W54_01880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W54_01885	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W54_01890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W54_01895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W54_01900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W54_01910	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W54_01915	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W54_01920	COG0089	rRNA binding
J5W54_01925	COG0088	Forms part of the polypeptide exit tunnel
J5W54_01930	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W54_01935	COG0051	transcription antitermination factor activity, RNA binding
J5W54_01945	COG0049	tRNA binding
J5W54_01950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W54_01955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W54_01965	COG3852	Histidine kinase
J5W54_01970	COG2204	response regulator
J5W54_01980	COG1722	exodeoxyribonuclease VII activity
J5W54_01985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W54_02000	COG0795	lipopolysaccharide-transporting ATPase activity
J5W54_02005	COG1160	GTP binding
J5W54_02010	COG0444	Belongs to the ABC transporter superfamily
J5W54_02025	COG1136	(ABC) transporter
J5W54_02025	COG0577	efflux transmembrane transporter activity
J5W54_02035	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W54_02080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W54_02135	COG1674	ftsk spoiiie
J5W54_02140	COG0799	negative regulation of ribosome biogenesis
J5W54_02145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W54_02200	COG0577	efflux transmembrane transporter activity
J5W54_02200	COG1136	(ABC) transporter
J5W54_02215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5W54_02225	COG4221	oxidoreductase activity
J5W54_02245	COG0038	chloride channel
J5W54_02255	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_02270	COG0076	glutamate decarboxylase activity
J5W54_02285	COG0167	dihydroorotate dehydrogenase activity
J5W54_02290	COG0352	thiamine-phosphate diphosphorylase activity
J5W54_02310	COG1253	flavin adenine dinucleotide binding
J5W54_02315	COG1253	flavin adenine dinucleotide binding
J5W54_02320	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W54_02325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W54_02330	COG0110	maltose O-acetyltransferase activity
J5W54_02355	COG0101	tRNA pseudouridine synthase activity
J5W54_02360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W54_02375	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W54_02390	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_02395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W54_02415	COG1136	(ABC) transporter
J5W54_02420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W54_02430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W54_02440	COG1116	anion transmembrane transporter activity
J5W54_02455	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_02460	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5W54_02465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W54_02475	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W54_02480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W54_02490	COG2814	Major facilitator Superfamily
J5W54_02500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W54_02505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W54_02505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W54_02510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W54_02515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W54_02520	COG0552	protein localization to endoplasmic reticulum
J5W54_02525	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W54_02545	COG1058	Belongs to the CinA family
J5W54_02545	COG1546	Belongs to the CinA family
J5W54_02555	COG0456	acetyltransferase
J5W54_02580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W54_02585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W54_02590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W54_02595	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W54_02610	COG0758	DNA mediated transformation
J5W54_02615	COG1686	Belongs to the peptidase S11 family
J5W54_02620	COG0012	GTP binding
J5W54_02625	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5W54_02635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W54_02635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W54_02650	COG3119	arylsulfatase activity
J5W54_02675	COG2259	Doxx family
J5W54_02680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W54_02710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W54_02730	COG2326	polyphosphate kinase activity
J5W54_02735	COG1349	DNA-binding transcription factor activity
J5W54_02760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W54_02765	COG1162	GTPase activity
J5W54_02780	COG0742	ribosomal rna small subunit methyltransferase
J5W54_02795	COG2326	polyphosphate kinase activity
J5W54_02805	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W54_02810	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W54_02820	COG1073	alpha beta
J5W54_02825	COG0802	atpase or kinase
J5W54_02830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W54_02835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W54_02840	COG0735	belongs to the Fur family
J5W54_02845	COG0396	ATPase activity
J5W54_02850	COG0719	Fe-S assembly protein
J5W54_02870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W54_02910	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W54_02930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W54_02935	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W54_02940	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W54_02945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W54_02950	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5W54_02955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W54_02965	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W54_03015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W54_03050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5W54_03055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W54_03060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5W54_03070	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W54_03080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W54_03085	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W54_03095	COG1363	Peptidase, m42
J5W54_03110	COG1077	Cell shape determining protein MreB Mrl
J5W54_03115	COG1530	ribonuclease E activity
J5W54_03135	COG0848	biopolymer transport protein
J5W54_03150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W54_03165	COG0134	indole-3-glycerol-phosphate synthase activity
J5W54_03170	COG0792	nuclease activity
J5W54_03180	COG1253	flavin adenine dinucleotide binding
J5W54_03190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W54_03195	COG0137	argininosuccinate synthase activity
J5W54_03210	COG0149	triose-phosphate isomerase activity
J5W54_03245	COG1040	competence protein
J5W54_03255	COG3956	TIGRFAM MazG family protein
J5W54_03275	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W54_03280	COG0612	Peptidase, M16
J5W54_03295	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W54_03300	COG0583	DNA-binding transcription factor activity
J5W54_03325	COG0673	inositol 2-dehydrogenase activity
J5W54_03330	COG3034	peptidoglycan biosynthetic process
J5W54_03350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W54_03355	COG0424	maF-like protein
J5W54_03360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W54_03390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W54_03400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W54_03410	COG0571	ribonuclease III activity
J5W54_03420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J5W54_03430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W54_03440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W54_03450	COG0438	transferase activity, transferring glycosyl groups
J5W54_03485	COG0463	Glycosyl transferase, family 2
J5W54_03485	COG1216	Glycosyl transferase, family 2
J5W54_03515	COG1053	succinate dehydrogenase
J5W54_03520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W54_03530	COG3209	COG3209 Rhs family protein
J5W54_03555	COG1490	D-aminoacyl-tRNA deacylase activity
J5W54_03570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W54_03575	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W54_03585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W54_03605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W54_03610	COG0724	RNA recognition motif
J5W54_03630	COG1716	ATPase activity
J5W54_03630	COG0842	Transport permease protein
J5W54_03630	COG1131	(ABC) transporter
J5W54_03640	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W54_03645	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W54_03650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W54_03655	COG0708	Exodeoxyribonuclease III
J5W54_03660	COG0195	Participates in both transcription termination and antitermination
J5W54_03665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W54_03670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W54_03680	COG3119	arylsulfatase activity
J5W54_03690	COG1966	Carbon starvation protein
J5W54_03700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W54_03710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W54_03715	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W54_03725	COG1216	Glycosyl transferase, family 2
J5W54_03730	COG1216	Glycosyl transferase, family 2
J5W54_03735	COG1216	Glycosyl transferase, family 2
J5W54_03740	COG1216	Glycosyl transferase, family 2
J5W54_03745	COG0482	sulfurtransferase activity
J5W54_03750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W54_03760	COG2860	membrane
J5W54_03765	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W54_03770	COG2001	Belongs to the MraZ family
J5W54_03775	COG0275	rRNA processing
J5W54_03785	COG0768	penicillin binding
J5W54_03790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W54_03795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W54_03800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W54_03805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W54_03815	COG0772	Belongs to the SEDS family
J5W54_03820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W54_03825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W54_03830	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W54_03840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5W54_03845	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W54_03850	COG0321	lipoyl(octanoyl) transferase activity
J5W54_03855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W54_03860	COG0066	3-isopropylmalate dehydratase activity
J5W54_03870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W54_03880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W54_03885	COG4608	Belongs to the ABC transporter superfamily
J5W54_03900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W54_03905	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W54_03915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W54_03930	COG1137	ATPase activity
J5W54_03940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W54_03965	COG3468	outer membrane autotransporter barrel domain protein
J5W54_04015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W54_04030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W54_04050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W54_04065	COG2226	methyltransferase
J5W54_04075	COG2076	Multidrug Resistance protein
J5W54_04155	COG2255	four-way junction helicase activity
J5W54_04160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W54_04165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W54_04170	COG1215	transferase activity, transferring glycosyl groups
J5W54_04180	COG0017	Asparaginyl-tRNA synthetase
J5W54_04190	COG3118	belongs to the thioredoxin family
J5W54_04235	COG0583	DNA-binding transcription factor activity
J5W54_04240	COG2855	membrane
J5W54_04245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W54_04255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W54_04265	COG0602	queuosine metabolic process
J5W54_04270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W54_04275	COG0217	transcriptional regulatory protein
J5W54_04280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W54_04285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W54_04285	COG4651	solute:proton antiporter activity
J5W54_04295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W54_04300	COG4864	UPF0365 protein
J5W54_04310	COG2022	thiamine diphosphate biosynthetic process
J5W54_04315	COG0531	amino acid
J5W54_04325	COG0628	permease
J5W54_04330	COG0019	diaminopimelate decarboxylase activity
J5W54_04335	COG0191	fructose-bisphosphate aldolase activity
J5W54_04340	COG1217	gtp-binding protein TYPA
J5W54_04370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W54_04380	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W54_04450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W54_04455	COG0516	GMP reductase activity
J5W54_04455	COG0517	IMP dehydrogenase activity
J5W54_04460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W54_04460	COG0519	Catalyzes the synthesis of GMP from XMP
J5W54_04470	COG0546	phosphoglycolate phosphatase activity
J5W54_04490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W54_04505	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W54_04510	COG0196	riboflavin kinase activity
J5W54_04515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W54_04525	COG1408	metallophosphoesterase
J5W54_04535	COG1216	Glycosyl transferase, family 2
J5W54_04535	COG1442	glycosyl transferase family 8
J5W54_04545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W54_04550	COG1216	Glycosyl transferase, family 2
J5W54_04575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W54_04575	COG2755	lipolytic protein G-D-S-L family
J5W54_04590	COG0471	metal ion transport
J5W54_04590	COG0490	domain, Protein
J5W54_04625	COG0588	phosphoglycerate mutase activity
J5W54_04630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W54_04640	COG0477	Major facilitator Superfamily
J5W54_04645	COG1607	acyl-coa hydrolase
J5W54_04655	COG1028	Short-chain dehydrogenase reductase Sdr
J5W54_04665	COG1525	nuclease
J5W54_04675	COG1475	DNA binding
J5W54_04680	COG3969	phosphoadenosine phosphosulfate
J5W54_04695	COG0473	3-isopropylmalate dehydrogenase activity
J5W54_04710	COG0606	chelatase, subunit chli
J5W54_04720	COG2873	o-acetylhomoserine
J5W54_04725	COG0535	radical SAM domain protein
J5W54_04730	COG0535	radical SAM domain protein
J5W54_04745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W54_04750	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5W54_04760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5W54_04765	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W54_04765	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W54_04765	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W54_04765	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W54_04775	COG1733	regulation of RNA biosynthetic process
J5W54_04785	COG0107	imidazoleglycerol-phosphate synthase activity
J5W54_04790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W54_04800	COG1643	Atp-dependent helicase
J5W54_04805	COG0440	acetolactate synthase activity
J5W54_04810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W54_04820	COG0445	tRNA wobble uridine modification
J5W54_04825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W54_04825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W54_04830	COG0592	DNA-directed DNA polymerase activity
J5W54_04885	COG0791	NLP P60 protein
J5W54_04885	COG1388	LysM domain
J5W54_04890	COG0084	hydrolase, TatD family'
J5W54_04900	COG3250	beta-galactosidase activity
J5W54_04915	COG2205	protein histidine kinase activity
J5W54_04920	COG0745	RESPONSE REGULATOR receiver
J5W54_04930	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W54_04955	COG0542	response to heat
J5W54_05000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W54_05010	COG0659	secondary active sulfate transmembrane transporter activity
J5W54_05015	COG0165	Argininosuccinate lyase
J5W54_05030	COG0148	phosphopyruvate hydratase activity
J5W54_05035	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W54_05060	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W54_05070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W54_05075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W54_05100	COG3345	alpha-galactosidase
J5W54_05135	COG0490	domain, Protein
J5W54_05135	COG2985	domain, Protein
J5W54_05150	COG0471	metal ion transport
J5W54_05175	COG2194	sulfuric ester hydrolase activity
J5W54_05180	COG1592	Rubrerythrin
J5W54_05190	COG1363	Peptidase, m42
J5W54_05195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_05205	COG1785	Belongs to the alkaline phosphatase family
J5W54_05210	COG1970	mechanosensitive ion channel activity
J5W54_05215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W54_05225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W54_05235	COG2217	Heavy metal translocating P-type atpase
J5W54_05245	COG0321	lipoyl(octanoyl) transferase activity
J5W54_05245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W54_05250	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J5W54_05285	COG0022	dehydrogenase e1 component
J5W54_05290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W54_05295	COG0789	Transcriptional regulator
J5W54_05300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W54_05310	COG3210	domain, Protein
J5W54_05360	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W54_05360	COG3409	Peptidoglycan-binding domain 1 protein
J5W54_05365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W54_05390	COG1690	Belongs to the RtcB family
J5W54_05400	COG2814	Major facilitator Superfamily
J5W54_05410	COG2096	Adenosyltransferase
J5W54_05420	COG0557	exoribonuclease II activity
J5W54_05450	COG0826	peptidase U32
J5W54_05455	COG0285	dihydrofolate synthase activity
J5W54_05470	COG0673	inositol 2-dehydrogenase activity
J5W54_05475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W54_05480	COG0737	Belongs to the 5'-nucleotidase family
J5W54_05490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W54_05495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W54_05510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W54_05515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W54_05520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W54_05525	COG0200	Binds to the 23S rRNA
J5W54_05530	COG0201	protein transport
J5W54_05535	COG0563	adenylate kinase activity
J5W54_05540	COG0024	Methionine aminopeptidase
J5W54_05555	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W54_05570	COG1442	glycosyl transferase family 8
J5W54_05575	COG1442	glycosyl transferase family 8
J5W54_05595	COG1028	Short-chain dehydrogenase reductase Sdr
J5W54_05605	COG0488	(ABC) transporter
J5W54_05615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W54_05625	COG1253	flavin adenine dinucleotide binding
J5W54_05630	COG1028	Short-chain dehydrogenase reductase Sdr
J5W54_05640	COG1073	alpha beta
J5W54_05650	COG0667	Aldo Keto reductase
J5W54_05705	COG2267	carboxylic ester hydrolase activity
J5W54_05710	COG2095	MarC family integral membrane protein
J5W54_05755	COG0488	(ABC) transporter
J5W54_05760	COG0697	spore germination
J5W54_05770	COG0215	cysteine-tRNA ligase activity
J5W54_05780	COG3119	arylsulfatase activity
J5W54_05795	COG0481	GTPase activity
J5W54_05815	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W54_05825	COG0222	ribosome binding
J5W54_05830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W54_05835	COG0081	regulation of translation
J5W54_05840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W54_05845	COG0250	Participates in transcription elongation, termination and antitermination
J5W54_05860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W54_05870	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W54_05880	COG0740	serine-type endopeptidase activity
J5W54_05885	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W54_05900	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W54_05925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W54_05965	COG2226	methyltransferase
J5W54_05970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W54_05975	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W54_05990	COG1902	pentaerythritol trinitrate reductase activity
J5W54_05990	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5W54_06000	COG3119	arylsulfatase activity
J5W54_06005	COG0514	ATP-dependent DNA helicase (RecQ)
J5W54_06025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W54_06030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W54_06085	COG1858	cytochrome C peroxidase
J5W54_06090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W54_06095	COG0590	tRNA wobble adenosine to inosine editing
J5W54_06100	COG1940	carbohydrate kinase activity
J5W54_06105	COG2217	Heavy metal translocating P-type atpase
J5W54_06145	COG1363	Peptidase, m42
J5W54_06150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W54_06160	COG0006	proline dipeptidase activity
J5W54_06165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W54_06185	COG5002	protein histidine kinase activity
J5W54_06190	COG0745	RESPONSE REGULATOR receiver
J5W54_06195	COG0129	dihydroxy-acid dehydratase activity
J5W54_06305	COG1368	sulfuric ester hydrolase activity
J5W54_06340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W54_06345	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W54_06365	COG0534	Mate efflux family protein
J5W54_06370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W54_06445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W54_06500	COG3266	domain, Protein
J5W54_06500	COG0515	serine threonine protein kinase
J5W54_06545	COG1876	peptidase activity
J5W54_06590	COG3209	COG3209 Rhs family protein
J5W54_06735	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W54_06740	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5W54_06745	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J5W54_06750	COG2205	protein histidine kinase activity
J5W54_06755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W54_06765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W54_06780	COG0667	Aldo Keto reductase
J5W54_06785	COG0789	Transcriptional regulator
J5W54_06830	COG0714	Associated with various cellular activities
J5W54_06860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W54_06865	COG1119	ATPase activity
J5W54_06870	COG2186	Transcriptional regulator
J5W54_06890	COG0148	phosphopyruvate hydratase activity
J5W54_06895	COG0436	Aminotransferase
J5W54_06900	COG1477	protein flavinylation
J5W54_06915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W54_06925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W54_06945	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W54_06955	COG1199	ATP-dependent helicase activity
J5W54_06960	COG1122	ATPase activity
J5W54_06985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W54_06990	COG0598	Magnesium transport protein CorA
J5W54_06995	COG0359	binds to the 23S rRNA
J5W54_07000	COG0138	bifunctional purine biosynthesis protein purh
J5W54_07005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W54_07010	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W54_07020	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W54_07025	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W54_07025	COG3409	Peptidoglycan-binding domain 1 protein
J5W54_07030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W54_07040	COG0437	4 iron, 4 sulfur cluster binding
J5W54_07060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W54_07115	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W54_07135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W54_07145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W54_07165	COG2003	Belongs to the UPF0758 family
J5W54_07170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W54_07170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W54_07175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W54_07180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W54_07185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W54_07190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W54_07195	COG0322	excinuclease ABC activity
J5W54_07200	COG0811	peptide transport
J5W54_07205	COG0848	biopolymer transport protein
J5W54_07215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W54_07220	COG0483	inositol monophosphate 1-phosphatase activity
J5W54_07225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W54_07235	COG1482	cell wall glycoprotein biosynthetic process
J5W54_07245	COG1757	Na H antiporter
J5W54_07250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W54_07255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W54_07260	COG0505	Belongs to the CarA family
J5W54_07265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W54_07275	COG0067	glutamate synthase
J5W54_07275	COG0070	glutamate synthase
J5W54_07275	COG0069	glutamate synthase activity
J5W54_07280	COG0706	membrane insertase activity
J5W54_07285	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5W54_07295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5W54_07305	COG2755	lipolytic protein G-D-S-L family
J5W54_07305	COG0657	acetylesterase activity
J5W54_07315	COG0676	glucose-6-phosphate 1-epimerase activity
J5W54_07320	COG0259	pyridoxamine-phosphate oxidase activity
J5W54_07335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W54_07350	COG1760	l-serine dehydratase
J5W54_07355	COG3118	belongs to the thioredoxin family
J5W54_07355	COG0492	ferredoxin-NADP+ reductase activity
J5W54_07410	COG1408	metallophosphoesterase
J5W54_07420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W54_07425	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W54_07440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5W54_07450	COG0826	peptidase U32
J5W54_07455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W54_07480	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5W54_07500	COG0529	Catalyzes the synthesis of activated sulfate
J5W54_07500	COG2895	sulfate adenylyltransferase (ATP) activity
J5W54_07505	COG0175	sulfate reduction
J5W54_07510	COG0175	sulfate reduction
J5W54_07530	COG0581	inorganic phosphate transmembrane transporter activity
J5W54_07535	COG0573	inorganic phosphate transmembrane transporter activity
J5W54_07545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W54_07555	COG2017	converts alpha-aldose to the beta-anomer
J5W54_07570	COG0612	Peptidase, M16
J5W54_07580	COG0110	maltose O-acetyltransferase activity
J5W54_07605	COG0233	cytoplasmic translational termination
J5W54_07610	COG0528	UMP kinase activity
J5W54_07615	COG0668	transmembrane transport
J5W54_07620	COG0450	alkyl hydroperoxide reductase
J5W54_07625	COG0733	neurotransmitter:sodium symporter activity
J5W54_07645	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W54_07655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W54_07660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W54_07665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W54_07690	COG0842	Transport permease protein
J5W54_07695	COG0842	Transport permease protein
J5W54_07700	COG1131	(ABC) transporter
J5W54_07710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W54_07715	COG1183	phosphatidylcholine synthase activity
J5W54_07725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W54_07735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W54_07740	COG1028	Short-chain dehydrogenase reductase Sdr
J5W54_07760	COG0156	8-amino-7-oxononanoate synthase activity
J5W54_07780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W54_07785	COG0124	histidyl-tRNA synthetase
J5W54_07790	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W54_07795	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W54_07800	COG0298	carbon dioxide binding
J5W54_07820	COG0438	transferase activity, transferring glycosyl groups
J5W54_07825	COG0443	Heat shock 70 kDa protein
J5W54_07830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W54_07835	COG0459	protein refolding
J5W54_07885	COG0632	four-way junction helicase activity
J5W54_07895	COG0126	phosphoglycerate kinase activity
J5W54_07905	COG1082	Xylose isomerase domain protein TIM barrel
J5W54_07915	COG0863	Belongs to the N(4) N(6)-methyltransferase family
J5W54_07925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W54_07935	COG2271	Major facilitator Superfamily
J5W54_07950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W54_07960	COG0037	tRNA processing
J5W54_07965	COG0254	rRNA binding
J5W54_08000	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W54_08005	COG0039	L-malate dehydrogenase activity
J5W54_08030	COG0778	Nitroreductase
J5W54_08035	COG0564	pseudouridine synthase activity
J5W54_08060	COG1126	abc transporter atp-binding protein
J5W54_08065	COG0765	amino acid transport
J5W54_08075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W54_08080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W54_08100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W54_08130	COG1872	DUF167
J5W54_08135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W54_08140	COG0484	heat shock protein binding
J5W54_08145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W54_08155	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W54_08170	COG0277	FAD linked oxidase domain protein
J5W54_08195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W54_08200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W54_08210	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W54_08215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W54_08220	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W54_08225	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W54_08240	COG1686	Belongs to the peptidase S11 family
J5W54_08245	COG0205	6-phosphofructokinase activity
J5W54_08255	COG0428	transporter
J5W54_08260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W54_08275	COG3977	Valine--pyruvate aminotransferase
J5W54_08280	COG1561	YicC-like family, N-terminal region
J5W54_08290	COG0471	metal ion transport
J5W54_08290	COG3273	potassium ion transport
J5W54_08295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W54_08310	COG1575	Belongs to the MenA family. Type 1 subfamily
J5W54_08345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W54_08345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W54_08365	COG0202	RNA polymerase activity
J5W54_08370	COG0203	ribosomal protein L17
J5W54_08375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W54_08385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W54_08400	COG2885	chlorophyll binding
J5W54_08455	COG0667	Aldo Keto reductase
J5W54_08460	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W54_08480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W54_08485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W54_08490	COG0134	indole-3-glycerol-phosphate synthase activity
J5W54_08495	COG0135	phosphoribosylanthranilate isomerase activity
J5W54_08500	COG0133	tryptophan synthase activity
J5W54_08505	COG0159	tryptophan synthase activity
J5W54_08525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W54_08530	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W54_08540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W54_08575	COG0561	phosphatase activity
J5W54_08580	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W54_08585	COG2223	nitrite transmembrane transporter activity
J5W54_08690	COG2314	TM2 domain
J5W54_08710	COG0515	serine threonine protein kinase
J5W54_08725	COG3177	Filamentation induced by cAMP protein fic
J5W54_08755	COG0556	nucleotide-excision repair
J5W54_08760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W54_08765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W54_08785	COG1074	ATP-dependent DNA helicase activity
J5W54_08805	COG1002	Type II restriction enzyme, methylase subunits
J5W54_08810	COG1061	Type III restriction enzyme res subunit
J5W54_08815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J5W54_08820	COG2373	Large extracellular alpha-helical protein
J5W54_08825	COG1979	alcohol dehydrogenase
J5W54_08835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5W54_08860	COG0372	Belongs to the citrate synthase family
J5W54_08875	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W54_08885	COG1187	pseudouridine synthase activity
J5W54_08895	COG0105	UTP biosynthetic process
J5W54_08900	COG1215	transferase activity, transferring glycosyl groups
J5W54_08905	COG0463	Glycosyl transferase, family 2
J5W54_08915	COG1459	type II secretion system
J5W54_08920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W54_08925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W54_08930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W54_08945	COG0728	peptidoglycan biosynthetic process
J5W54_08950	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W54_08950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W54_08960	COG1649	PFAM Uncharacterised BCR, COG1649
J5W54_08965	COG1691	(AIR) carboxylase
J5W54_08970	COG0037	tRNA processing
J5W54_08975	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W54_08980	COG0142	geranyltranstransferase activity
J5W54_08995	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W54_09015	COG1007	ATP synthesis coupled electron transport
J5W54_09020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W54_09030	COG0713	ATP synthesis coupled electron transport
J5W54_09035	COG0839	Belongs to the complex I subunit 6 family
J5W54_09045	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W54_09050	COG1034	ATP synthesis coupled electron transport
J5W54_09055	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W54_09060	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W54_09065	COG0649	NAD binding
J5W54_09075	COG0726	polysaccharide deacetylase
J5W54_09085	COG0307	riboflavin synthase, alpha
J5W54_09090	COG2264	protein methyltransferase activity
J5W54_09100	COG3210	domain, Protein
J5W54_09105	COG1640	4-alpha-glucanotransferase
J5W54_09115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W54_09120	COG1030	water channel activity
J5W54_09125	COG0358	DNA primase activity
J5W54_09130	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5W54_09135	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W54_09150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W54_09155	COG0793	Belongs to the peptidase S41A family
J5W54_09170	COG1643	Atp-dependent helicase
J5W54_09195	COG1450	Type ii and iii secretion system protein
J5W54_09210	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W54_09245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W54_09250	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W54_09260	COG0268	Binds directly to 16S ribosomal RNA
J5W54_09265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W54_09270	COG0028	Belongs to the TPP enzyme family
J5W54_09280	COG0688	phosphatidylethanolamine metabolic process
J5W54_09285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W54_09290	COG0495	leucyl-tRNA aminoacylation
J5W54_09295	COG3119	arylsulfatase activity
J5W54_09310	COG1166	arginine decarboxylase activity
J5W54_09320	COG3250	beta-galactosidase activity
J5W54_09325	COG3250	beta-galactosidase activity
J5W54_09330	COG3250	beta-galactosidase activity
J5W54_09335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W54_09340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_09350	COG0205	6-phosphofructokinase activity
J5W54_09370	COG0535	radical SAM domain protein
J5W54_09410	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W54_09415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W54_09420	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J5W54_09435	COG4771	TonB-dependent receptor
J5W54_09455	COG0402	S-adenosylhomocysteine deaminase activity
J5W54_09460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W54_09465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5W54_09495	COG0582	viral genome integration into host DNA
J5W54_09500	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W54_09510	COG1294	oxidase, subunit
J5W54_09515	COG1271	oxidase subunit
J5W54_09525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W54_09545	COG1846	Transcriptional regulator
J5W54_09575	COG2949	membrane
J5W54_09600	COG0514	ATP-dependent DNA helicase (RecQ)
J5W54_09615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W54_09620	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W54_09625	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W54_09680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W54_09685	COG2205	protein histidine kinase activity
J5W54_09700	COG0113	porphobilinogen synthase activity
J5W54_09710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5W54_09730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W54_09755	COG4106	trans-aconitate 2-methyltransferase activity
J5W54_09770	COG3475	LICD family
J5W54_09775	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W54_09785	COG3475	LICD family
J5W54_09800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W54_09805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W54_09815	COG3475	LICD family
J5W54_09820	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W54_09830	COG2166	iron-sulfur cluster assembly
J5W54_09835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W54_09845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W54_09850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W54_09855	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W54_09860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W54_09865	COG1131	(ABC) transporter
J5W54_09880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W54_09895	COG1215	transferase activity, transferring glycosyl groups
J5W54_09910	COG1401	restriction endodeoxyribonuclease activity
J5W54_09910	COG1401	restriction endodeoxyribonuclease activity
J5W54_09925	COG1522	sequence-specific DNA binding
J5W54_09930	COG0436	Aminotransferase
J5W54_09945	COG0423	glycine-tRNA ligase activity
J5W54_09950	COG0656	L-ascorbic acid biosynthetic process
J5W54_09965	COG2304	oxidoreductase activity
J5W54_09980	COG0714	Associated with various cellular activities
J5W54_09985	COG0154	amidase activity
J5W54_09990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W54_10030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W54_10085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W54_10095	COG0656	L-ascorbic acid biosynthetic process
J5W54_10105	COG0667	Aldo Keto reductase
J5W54_10110	COG1408	metallophosphoesterase
J5W54_10130	COG0789	Transcriptional regulator
J5W54_10145	COG0534	Mate efflux family protein
J5W54_10170	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W54_10185	COG1837	Belongs to the UPF0109 family
J5W54_10190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W54_10195	COG0363	glucosamine-6-phosphate deaminase activity
J5W54_10210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W54_10230	COG1741	Belongs to the pirin family
J5W54_10260	COG1070	Carbohydrate kinase
J5W54_10275	COG0738	Major facilitator superfamily
J5W54_10290	COG1595	DNA-templated transcription, initiation
J5W54_10305	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5W54_10325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W54_10335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W54_10340	COG2132	Multicopper oxidase
J5W54_10345	COG0697	spore germination
J5W54_10355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W54_10360	COG4608	Belongs to the ABC transporter superfamily
J5W54_10365	COG0444	Belongs to the ABC transporter superfamily
J5W54_10375	COG4166	transmembrane transport
J5W54_10380	COG4239	(ABC) transporter, permease
J5W54_10385	COG0601	transmembrane transport
J5W54_10400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W54_10405	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W54_10410	COG3738	Protein conserved in bacteria
J5W54_10415	COG0151	Belongs to the GarS family
J5W54_10430	COG0811	peptide transport
J5W54_10440	COG0242	peptide deformylase activity
J5W54_10480	COG3258	Cytochrome c
J5W54_10495	COG3274	enterobacterial common antigen metabolic process
J5W54_10500	COG0538	isocitrate dehydrogenase activity
J5W54_10515	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W54_10520	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W54_10525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W54_10535	COG0668	transmembrane transport
J5W54_10540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W54_10540	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W54_10545	COG0805	protein transport
J5W54_10550	COG1968	undecaprenyl-diphosphatase activity
J5W54_10570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W54_10580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W54_10590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W54_10600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W54_10610	COG1408	metallophosphoesterase
J5W54_10635	COG4974	Belongs to the 'phage' integrase family
J5W54_10660	COG1454	alcohol dehydrogenase
J5W54_10665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W54_10675	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W54_10675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W54_10680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W54_10715	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W54_10725	COG4607	ABC-type enterochelin transport system periplasmic component
J5W54_10730	COG4604	ABC transporter, ATP-binding protein
J5W54_10735	COG4605	iron ion homeostasis
J5W54_10740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5W54_10775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W54_10775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W54_10790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W54_10795	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W54_10815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W54_10830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W54_10855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W54_10890	COG1410	methionine synthase
J5W54_10890	COG0646	methionine synthase
J5W54_10895	COG2966	Psort location CytoplasmicMembrane, score
J5W54_10900	COG3610	response to peptide
J5W54_10910	COG0460	homoserine dehydrogenase
J5W54_10915	COG0527	aspartate kinase activity
J5W54_10925	COG5522	Integral membrane protein (intg_mem_TP0381)
J5W54_10935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W54_10940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W54_10950	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W54_10955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W54_10955	COG0574	Belongs to the PEP-utilizing enzyme family
J5W54_10960	COG0166	Belongs to the GPI family
J5W54_10970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W54_10980	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W54_10980	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W54_11015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W54_11020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W54_11025	COG2818	Glycosylase
J5W54_11050	COG3033	Beta-eliminating lyase
J5W54_11065	COG0072	phenylalanine-tRNA ligase activity
J5W54_11065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W54_11085	COG0326	Molecular chaperone. Has ATPase activity
J5W54_11090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W54_11115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W54_11120	COG1959	2 iron, 2 sulfur cluster binding
J5W54_11135	COG0352	thiamine-phosphate diphosphorylase activity
J5W54_11140	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W54_11155	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_11165	COG1703	isobutyryl-CoA mutase activity
J5W54_11185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W54_11195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W54_11200	COG0418	dihydroorotase activity
J5W54_11215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W54_11235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W54_11265	COG0534	Mate efflux family protein
J5W54_11270	COG0489	protein tyrosine kinase activity
J5W54_11280	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W54_11295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W54_11305	COG1538	Outer membrane efflux protein
J5W54_11320	COG4112	unkown
J5W54_11335	COG0038	chloride channel
J5W54_11345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W54_11350	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W54_11355	COG0586	Pfam SNARE associated Golgi protein
J5W54_11780	COG1012	belongs to the aldehyde dehydrogenase family
J5W54_11800	COG0753	catalase activity
J5W54_11810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W54_11815	COG1592	Rubrerythrin
J5W54_11820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5W54_11830	COG1674	ftsk spoiiie
J5W54_12055	COG0863	Belongs to the N(4) N(6)-methyltransferase family
J5W54_12065	COG0489	protein tyrosine kinase activity
J5W54_12075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W54_12085	COG0438	transferase activity, transferring glycosyl groups
J5W54_12095	COG0438	transferase activity, transferring glycosyl groups
J5W54_12130	COG0438	transferase activity, transferring glycosyl groups
J5W54_12140	COG0110	maltose O-acetyltransferase activity
J5W54_12150	COG1216	Glycosyl transferase, family 2
J5W54_12155	COG1216	Glycosyl transferase, family 2
J5W54_12185	COG2755	lipolytic protein G-D-S-L family
J5W54_12185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W54_12210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W54_12215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W54_12220	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W54_12225	COG0280	phosphate acetyltransferase
J5W54_12225	COG0281	malic enzyme
J5W54_12265	COG1472	Belongs to the glycosyl hydrolase 3 family
J5W54_12270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W54_12285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W54_12325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W54_12330	COG1063	alcohol dehydrogenase
J5W54_12345	COG0714	Associated with various cellular activities
J5W54_12355	COG0193	aminoacyl-tRNA hydrolase activity
J5W54_12360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W54_12375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5W54_12395	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W54_12410	COG0375	protein maturation
J5W54_12440	COG0778	Nitroreductase
J5W54_12445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W54_12465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W54_12475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W54_12475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W54_12495	COG0863	Belongs to the N(4) N(6)-methyltransferase family
J5W54_12515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W54_12520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5W54_12525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W54_12575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W54_12580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W54_12595	COG0318	PFAM AMP-dependent synthetase and ligase
J5W54_12615	COG0339	signal peptide processing
J5W54_12625	COG0018	arginyl-trna synthetase
J5W54_12665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W54_12670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W54_12675	COG0653	protein targeting
J5W54_12690	COG0494	nUDIX hydrolase