locus-tag	class	description
J5W78_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5W78_00010	COG1131	(ABC) transporter
J5W78_00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J5W78_00035	COG0564	pseudouridine synthase activity
J5W78_00060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5W78_00065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5W78_00070	COG3177	Filamentation induced by cAMP protein fic
J5W78_00075	COG0513	Belongs to the DEAD box helicase family
J5W78_00085	COG0673	inositol 2-dehydrogenase activity
J5W78_00110	COG2814	Major facilitator Superfamily
J5W78_00115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5W78_00125	COG1971	Probably functions as a manganese efflux pump
J5W78_00155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W78_00180	COG0442	prolyl-tRNA aminoacylation
J5W78_00520	COG0531	amino acid
J5W78_00525	COG2066	Belongs to the glutaminase family
J5W78_00535	COG1115	amino acid carrier protein
J5W78_00545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W78_00550	COG2890	protein-(glutamine-N5) methyltransferase activity
J5W78_00555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5W78_00560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5W78_00580	COG2226	methyltransferase
J5W78_00585	COG0534	Mate efflux family protein
J5W78_00600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W78_00605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5W78_00610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_00630	COG1121	(ABC) transporter
J5W78_00635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5W78_00640	COG3880	PFAM UvrB UvrC protein
J5W78_00645	COG3869	Catalyzes the specific phosphorylation of arginine residues in
J5W78_00650	COG0542	response to heat
J5W78_00660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5W78_00665	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5W78_00670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W78_00685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W78_00685	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5W78_00695	COG0180	Tryptophanyl-tRNA synthetase
J5W78_00705	COG1692	metallophosphoesterase
J5W78_00715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5W78_00770	COG0443	Heat shock 70 kDa protein
J5W78_00775	COG0443	Heat shock 70 kDa protein
J5W78_00825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5W78_00830	COG0246	Mannitol dehydrogenase
J5W78_00835	COG0738	Major facilitator superfamily
J5W78_00855	COG0156	8-amino-7-oxononanoate synthase activity
J5W78_00865	COG1192	Involved in chromosome partitioning
J5W78_00870	COG0515	serine threonine protein kinase
J5W78_00870	COG3266	domain, Protein
J5W78_00915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5W78_00925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W78_00935	COG3189	MarR family transcriptional regulator
J5W78_00940	COG0181	hydroxymethylbilane synthase activity
J5W78_00945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J5W78_00955	COG1469	GTP cyclohydrolase I activity
J5W78_00960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5W78_00965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5W78_00970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J5W78_00975	COG1940	carbohydrate kinase activity
J5W78_00990	COG0494	nUDIX hydrolase
J5W78_01005	COG1136	(ABC) transporter
J5W78_01005	COG0577	efflux transmembrane transporter activity
J5W78_01010	COG1136	(ABC) transporter
J5W78_01010	COG0577	efflux transmembrane transporter activity
J5W78_01015	COG1538	Outer membrane efflux protein
J5W78_01020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5W78_01050	COG1720	tRNA m6t6A37 methyltransferase activity
J5W78_01055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5W78_01060	COG0540	Belongs to the ATCase OTCase family
J5W78_01065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J5W78_01120	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J5W78_01125	COG2957	Belongs to the agmatine deiminase family
J5W78_01140	COG0750	zinc metalloprotease
J5W78_01150	COG3119	arylsulfatase activity
J5W78_01160	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W78_01160	COG1918	ferrous iron import across plasma membrane
J5W78_01200	COG1475	DNA binding
J5W78_01235	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5W78_01250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5W78_01255	COG0601	transmembrane transport
J5W78_01305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5W78_01320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5W78_01325	COG1132	(ABC) transporter
J5W78_01330	COG1132	(ABC) transporter
J5W78_01345	COG1127	ABC transporter
J5W78_01350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5W78_01385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5W78_01405	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5W78_01410	COG0504	CTP synthase activity
J5W78_01415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5W78_01445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_01455	COG1322	Protein conserved in bacteria
J5W78_01460	COG0546	phosphoglycolate phosphatase activity
J5W78_01465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W78_01475	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W78_01475	COG4591	ABC-type transport system involved in lipoprotein release permease component
J5W78_01500	COG2234	aminopeptidase activity
J5W78_01505	COG2755	lipolytic protein G-D-S-L family
J5W78_01505	COG0657	acetylesterase activity
J5W78_01510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5W78_01530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5W78_01565	COG0335	large ribosomal subunit rRNA binding
J5W78_01575	COG0346	lactoylglutathione lyase activity
J5W78_01590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J5W78_01595	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J5W78_01605	COG0427	acetyl-CoA hydrolase
J5W78_01615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5W78_01625	COG0205	6-phosphofructokinase activity
J5W78_01640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W78_01645	COG0028	Belongs to the TPP enzyme family
J5W78_01660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J5W78_01675	COG0471	metal ion transport
J5W78_01685	COG0351	phosphomethylpyrimidine kinase
J5W78_01760	COG1028	Short-chain dehydrogenase reductase Sdr
J5W78_01770	COG0242	peptide deformylase activity
J5W78_01775	COG1063	alcohol dehydrogenase
J5W78_01785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5W78_01790	COG1393	Belongs to the ArsC family
J5W78_01795	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W78_01820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5W78_01830	COG1187	pseudouridine synthase activity
J5W78_01840	COG0336	Belongs to the RNA methyltransferase TrmD family
J5W78_01855	COG0539	negative regulation of cytoplasmic translation
J5W78_01920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5W78_01925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5W78_01930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5W78_01970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W78_02005	COG1083	cytidylyl-transferase
J5W78_02120	COG0305	Participates in initiation and elongation during chromosome replication
J5W78_02215	COG3969	phosphoadenosine phosphosulfate
J5W78_02245	COG0662	Cupin 2, conserved barrel domain protein
J5W78_02245	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5W78_02255	COG0416	fatty acid biosynthetic process
J5W78_02260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5W78_02270	COG0537	adenosine 5'-monophosphoramidase activity
J5W78_02275	COG0009	L-threonylcarbamoyladenylate synthase
J5W78_02280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5W78_02285	COG0228	four-way junction DNA binding
J5W78_02310	COG0343	queuine tRNA-ribosyltransferase activity
J5W78_02315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5W78_02325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5W78_02335	COG0776	regulation of translation
J5W78_02365	COG0811	peptide transport
J5W78_02380	COG3250	beta-galactosidase activity
J5W78_02385	COG0525	valine-tRNA ligase activity
J5W78_02395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5W78_02400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5W78_02405	COG0255	Belongs to the universal ribosomal protein uL29 family
J5W78_02410	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5W78_02415	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5W78_02420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5W78_02430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5W78_02435	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5W78_02440	COG0089	rRNA binding
J5W78_02445	COG0088	Forms part of the polypeptide exit tunnel
J5W78_02450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5W78_02455	COG0051	transcription antitermination factor activity, RNA binding
J5W78_02460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5W78_02465	COG0049	tRNA binding
J5W78_02470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5W78_02480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5W78_02490	COG3852	Histidine kinase
J5W78_02495	COG2204	response regulator
J5W78_02505	COG1722	exodeoxyribonuclease VII activity
J5W78_02510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5W78_02525	COG0795	lipopolysaccharide-transporting ATPase activity
J5W78_02530	COG1160	GTP binding
J5W78_02535	COG0444	Belongs to the ABC transporter superfamily
J5W78_02570	COG0577	efflux transmembrane transporter activity
J5W78_02570	COG1136	(ABC) transporter
J5W78_02625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5W78_02630	COG0799	negative regulation of ribosome biogenesis
J5W78_02635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5W78_02690	COG1136	(ABC) transporter
J5W78_02705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J5W78_02715	COG4221	oxidoreductase activity
J5W78_02735	COG0038	chloride channel
J5W78_02750	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_02780	COG0067	glutamate synthase
J5W78_02780	COG0069	glutamate synthase activity
J5W78_02780	COG0070	glutamate synthase
J5W78_02790	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W78_02795	COG0505	Belongs to the CarA family
J5W78_02800	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J5W78_02805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W78_02810	COG1757	Na H antiporter
J5W78_02820	COG1482	cell wall glycoprotein biosynthetic process
J5W78_02830	COG0076	glutamate decarboxylase activity
J5W78_02835	COG3468	outer membrane autotransporter barrel domain protein
J5W78_02850	COG0167	dihydroorotate dehydrogenase activity
J5W78_02855	COG0352	thiamine-phosphate diphosphorylase activity
J5W78_02875	COG1253	flavin adenine dinucleotide binding
J5W78_02880	COG1253	flavin adenine dinucleotide binding
J5W78_02890	COG1185	polyribonucleotide nucleotidyltransferase activity
J5W78_02910	COG1309	transcriptional regulator
J5W78_02915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5W78_02950	COG0101	tRNA pseudouridine synthase activity
J5W78_02955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5W78_02975	COG4968	Prepilin-type N-terminal cleavage methylation domain
J5W78_02980	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J5W78_02990	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_02995	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5W78_03015	COG2234	aminopeptidase activity
J5W78_03020	COG1136	(ABC) transporter
J5W78_03025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5W78_03035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W78_03060	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_03070	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5W78_03075	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5W78_03085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5W78_03090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5W78_03100	COG2814	Major facilitator Superfamily
J5W78_03115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W78_03120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W78_03120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5W78_03125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5W78_03130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5W78_03135	COG0552	protein localization to endoplasmic reticulum
J5W78_03140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5W78_03160	COG1546	Belongs to the CinA family
J5W78_03160	COG1058	Belongs to the CinA family
J5W78_03170	COG0456	acetyltransferase
J5W78_03195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5W78_03200	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5W78_03205	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5W78_03210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5W78_03225	COG0758	DNA mediated transformation
J5W78_03235	COG1686	Belongs to the peptidase S11 family
J5W78_03240	COG0012	GTP binding
J5W78_03245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5W78_03255	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W78_03255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5W78_03270	COG3119	arylsulfatase activity
J5W78_03295	COG2755	lipolytic protein G-D-S-L family
J5W78_03295	COG0657	acetylesterase activity
J5W78_03305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5W78_03325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_03335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W78_03355	COG2326	polyphosphate kinase activity
J5W78_03360	COG1349	DNA-binding transcription factor activity
J5W78_03380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5W78_03400	COG0742	ribosomal rna small subunit methyltransferase
J5W78_03415	COG2326	polyphosphate kinase activity
J5W78_03420	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W78_03430	COG1073	alpha beta
J5W78_03435	COG0802	atpase or kinase
J5W78_03440	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5W78_03445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5W78_03450	COG0735	belongs to the Fur family
J5W78_03455	COG0396	ATPase activity
J5W78_03460	COG0719	Fe-S assembly protein
J5W78_03485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5W78_03525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W78_03570	COG3209	COG3209 Rhs family protein
J5W78_03580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5W78_03585	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W78_03590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5W78_03595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5W78_03600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5W78_03605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5W78_03615	COG0356	it plays a direct role in the translocation of protons across the membrane
J5W78_03675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5W78_03700	COG1045	serine acetyltransferase
J5W78_03710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5W78_03715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5W78_03725	COG0753	catalase activity
J5W78_03735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5W78_03745	COG3119	arylsulfatase activity
J5W78_03770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5W78_03780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5W78_03785	COG0047	phosphoribosylformylglycinamidine synthase activity
J5W78_03795	COG1363	Peptidase, m42
J5W78_03810	COG1077	Cell shape determining protein MreB Mrl
J5W78_03815	COG1530	ribonuclease E activity
J5W78_03845	COG0848	biopolymer transport protein
J5W78_03860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5W78_03880	COG0134	indole-3-glycerol-phosphate synthase activity
J5W78_03885	COG2217	Heavy metal translocating P-type atpase
J5W78_03890	COG0792	nuclease activity
J5W78_03900	COG1253	flavin adenine dinucleotide binding
J5W78_03910	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5W78_03925	COG0137	argininosuccinate synthase activity
J5W78_03930	COG3119	arylsulfatase activity
J5W78_03940	COG0149	triose-phosphate isomerase activity
J5W78_03975	COG1040	competence protein
J5W78_03985	COG3956	TIGRFAM MazG family protein
J5W78_04020	COG1663	tetraacyldisaccharide 4'-kinase activity
J5W78_04025	COG0612	Peptidase, M16
J5W78_04060	COG0673	inositol 2-dehydrogenase activity
J5W78_04065	COG3034	peptidoglycan biosynthetic process
J5W78_04085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5W78_04090	COG0424	maF-like protein
J5W78_04100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5W78_04105	COG0515	serine threonine protein kinase
J5W78_04105	COG2815	serine threonine protein kinase
J5W78_04120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J5W78_04130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5W78_04140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5W78_04150	COG0571	ribonuclease III activity
J5W78_04170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5W78_04185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5W78_04210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5W78_04400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_04405	COG2255	four-way junction helicase activity
J5W78_04410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5W78_04415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W78_04420	COG1215	transferase activity, transferring glycosyl groups
J5W78_04430	COG1215	transferase activity, transferring glycosyl groups
J5W78_04435	COG1215	transferase activity, transferring glycosyl groups
J5W78_04470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5W78_04485	COG0482	sulfurtransferase activity
J5W78_04490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5W78_04500	COG2860	membrane
J5W78_04505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W78_04510	COG2001	Belongs to the MraZ family
J5W78_04515	COG0275	rRNA processing
J5W78_04525	COG0768	penicillin binding
J5W78_04530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5W78_04535	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J5W78_04540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5W78_04545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5W78_04555	COG0772	Belongs to the SEDS family
J5W78_04560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5W78_04565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W78_04570	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W78_04585	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5W78_04590	COG0321	lipoyl(octanoyl) transferase activity
J5W78_04595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5W78_04600	COG0066	3-isopropylmalate dehydratase activity
J5W78_04610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_04620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W78_04635	COG3209	COG3209 Rhs family protein
J5W78_04640	COG4608	Belongs to the ABC transporter superfamily
J5W78_04655	COG0052	Belongs to the universal ribosomal protein uS2 family
J5W78_04660	COG0534	Mate efflux family protein
J5W78_04670	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5W78_04685	COG1137	ATPase activity
J5W78_04695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5W78_04725	COG0017	Asparaginyl-tRNA synthetase
J5W78_04735	COG3118	belongs to the thioredoxin family
J5W78_04795	COG0583	DNA-binding transcription factor activity
J5W78_04800	COG2855	membrane
J5W78_04805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W78_04820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5W78_04830	COG0602	queuosine metabolic process
J5W78_04835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W78_04840	COG0217	transcriptional regulatory protein
J5W78_04850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5W78_04855	COG4106	trans-aconitate 2-methyltransferase activity
J5W78_04860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W78_04860	COG4651	solute:proton antiporter activity
J5W78_04880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5W78_04885	COG4864	UPF0365 protein
J5W78_04895	COG2022	thiamine diphosphate biosynthetic process
J5W78_04900	COG0531	amino acid
J5W78_04910	COG0628	permease
J5W78_04915	COG0019	diaminopimelate decarboxylase activity
J5W78_04925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_04930	COG0191	fructose-bisphosphate aldolase activity
J5W78_04955	COG1217	gtp-binding protein TYPA
J5W78_04980	COG3152	Membrane
J5W78_04985	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5W78_04995	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5W78_05025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W78_05030	COG0517	IMP dehydrogenase activity
J5W78_05030	COG0516	GMP reductase activity
J5W78_05035	COG0519	Catalyzes the synthesis of GMP from XMP
J5W78_05035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W78_05050	COG0546	phosphoglycolate phosphatase activity
J5W78_05065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5W78_05080	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5W78_05085	COG0196	riboflavin kinase activity
J5W78_05090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5W78_05105	COG1408	metallophosphoesterase
J5W78_05120	COG1216	Glycosyl transferase, family 2
J5W78_05120	COG1442	glycosyl transferase family 8
J5W78_05130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W78_05135	COG1216	Glycosyl transferase, family 2
J5W78_05145	COG0297	glycogen (starch) synthase activity
J5W78_05155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W78_05155	COG2755	lipolytic protein G-D-S-L family
J5W78_05175	COG0490	domain, Protein
J5W78_05175	COG0471	metal ion transport
J5W78_05290	COG0588	phosphoglycerate mutase activity
J5W78_05295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5W78_05315	COG0477	Major facilitator Superfamily
J5W78_05320	COG1607	acyl-coa hydrolase
J5W78_05345	COG1028	Short-chain dehydrogenase reductase Sdr
J5W78_05350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J5W78_05370	COG1525	nuclease
J5W78_05380	COG1475	DNA binding
J5W78_05385	COG3969	phosphoadenosine phosphosulfate
J5W78_05415	COG0606	chelatase, subunit chli
J5W78_05425	COG2873	o-acetylhomoserine
J5W78_05430	COG0535	radical SAM domain protein
J5W78_05435	COG0535	radical SAM domain protein
J5W78_05455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W78_05460	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5W78_05470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5W78_05475	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5W78_05475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J5W78_05475	COG1013	pyruvate-flavodoxin oxidoreductase activity
J5W78_05475	COG0674	pyruvate-flavodoxin oxidoreductase activity
J5W78_05500	COG0107	imidazoleglycerol-phosphate synthase activity
J5W78_05515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W78_05525	COG1643	Atp-dependent helicase
J5W78_05530	COG0440	acetolactate synthase activity
J5W78_05535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_05545	COG0445	tRNA wobble uridine modification
J5W78_05550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W78_05550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5W78_05555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5W78_05565	COG0592	DNA-directed DNA polymerase activity
J5W78_05630	COG0791	NLP P60 protein
J5W78_05630	COG1388	LysM domain
J5W78_05635	COG0084	hydrolase, TatD family'
J5W78_05645	COG3250	beta-galactosidase activity
J5W78_05665	COG2205	protein histidine kinase activity
J5W78_05670	COG0745	RESPONSE REGULATOR receiver
J5W78_05680	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5W78_05690	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J5W78_05695	COG3345	alpha-galactosidase
J5W78_05700	COG0542	response to heat
J5W78_05740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5W78_05755	COG1733	regulation of RNA biosynthetic process
J5W78_05760	COG0659	secondary active sulfate transmembrane transporter activity
J5W78_05765	COG0165	Argininosuccinate lyase
J5W78_05780	COG0148	phosphopyruvate hydratase activity
J5W78_05785	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J5W78_05810	COG3481	metal-dependent phosphohydrolase, HD sub domain
J5W78_05820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W78_05825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5W78_05855	COG3345	alpha-galactosidase
J5W78_05895	COG1592	Rubrerythrin
J5W78_05905	COG1363	Peptidase, m42
J5W78_05910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_05920	COG1785	Belongs to the alkaline phosphatase family
J5W78_05925	COG1970	mechanosensitive ion channel activity
J5W78_05930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5W78_05940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5W78_05945	COG2755	lipolytic protein G-D-S-L family
J5W78_05945	COG0657	acetylesterase activity
J5W78_05955	COG2217	Heavy metal translocating P-type atpase
J5W78_05960	COG0497	DNA recombination
J5W78_05965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5W78_05965	COG0321	lipoyl(octanoyl) transferase activity
J5W78_05970	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J5W78_06000	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W78_06005	COG0022	dehydrogenase e1 component
J5W78_06015	COG4978	Transcriptional regulator
J5W78_06015	COG0789	Transcriptional regulator
J5W78_06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W78_06025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W78_06030	COG2738	Putative neutral zinc metallopeptidase
J5W78_06060	COG0656	L-ascorbic acid biosynthetic process
J5W78_06065	COG3409	Peptidoglycan-binding domain 1 protein
J5W78_06065	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W78_06070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5W78_06110	COG1690	Belongs to the RtcB family
J5W78_06120	COG2814	Major facilitator Superfamily
J5W78_06125	COG2096	Adenosyltransferase
J5W78_06140	COG3209	COG3209 Rhs family protein
J5W78_06180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W78_06190	COG0557	exoribonuclease II activity
J5W78_06195	COG0826	peptidase U32
J5W78_06200	COG0285	dihydrofolate synthase activity
J5W78_06215	COG0673	inositol 2-dehydrogenase activity
J5W78_06235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W78_06455	COG0737	Belongs to the 5'-nucleotidase family
J5W78_06465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5W78_06470	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5W78_06485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5W78_06490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5W78_06495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5W78_06500	COG0200	Binds to the 23S rRNA
J5W78_06505	COG0201	protein transport
J5W78_06510	COG0563	adenylate kinase activity
J5W78_06515	COG0024	Methionine aminopeptidase
J5W78_06530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5W78_06545	COG1442	glycosyl transferase family 8
J5W78_06550	COG1442	glycosyl transferase family 8
J5W78_06555	COG1216	Glycosyl transferase, family 2
J5W78_06560	COG1216	Glycosyl transferase, family 2
J5W78_06565	COG1216	Glycosyl transferase, family 2
J5W78_06570	COG1216	Glycosyl transferase, family 2
J5W78_06580	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W78_06585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5W78_06595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W78_06605	COG1966	Carbon starvation protein
J5W78_06615	COG3119	arylsulfatase activity
J5W78_06620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5W78_06625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5W78_06630	COG0195	Participates in both transcription termination and antitermination
J5W78_06635	COG0708	Exodeoxyribonuclease III
J5W78_06640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5W78_06645	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J5W78_06650	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5W78_06675	COG1131	(ABC) transporter
J5W78_06675	COG0842	Transport permease protein
J5W78_06675	COG1716	ATPase activity
J5W78_06695	COG0724	RNA recognition motif
J5W78_06700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W78_06725	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5W78_06735	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5W78_06740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5W78_06755	COG1490	D-aminoacyl-tRNA deacylase activity
J5W78_06760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5W78_06765	COG1053	succinate dehydrogenase
J5W78_06810	COG1028	Short-chain dehydrogenase reductase Sdr
J5W78_06820	COG0488	(ABC) transporter
J5W78_06830	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5W78_06850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5W78_06860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W78_06865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5W78_06920	COG2267	carboxylic ester hydrolase activity
J5W78_06925	COG2095	MarC family integral membrane protein
J5W78_06975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J5W78_06980	COG0488	(ABC) transporter
J5W78_06990	COG0697	spore germination
J5W78_07000	COG0215	cysteine-tRNA ligase activity
J5W78_07005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_07010	COG3119	arylsulfatase activity
J5W78_07020	COG0481	GTPase activity
J5W78_07045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5W78_07050	COG0085	RNA polymerase activity
J5W78_07055	COG0222	ribosome binding
J5W78_07060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5W78_07065	COG0081	regulation of translation
J5W78_07070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5W78_07075	COG0250	Participates in transcription elongation, termination and antitermination
J5W78_07090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5W78_07100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5W78_07105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5W78_07110	COG0740	serine-type endopeptidase activity
J5W78_07115	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5W78_07130	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J5W78_07150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5W78_07195	COG2226	methyltransferase
J5W78_07200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5W78_07205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5W78_07215	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5W78_07215	COG1902	pentaerythritol trinitrate reductase activity
J5W78_07225	COG3119	arylsulfatase activity
J5W78_07230	COG0514	ATP-dependent DNA helicase (RecQ)
J5W78_07250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5W78_07255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5W78_07270	COG2217	Heavy metal translocating P-type atpase
J5W78_07320	COG1858	cytochrome C peroxidase
J5W78_07325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5W78_07330	COG0590	tRNA wobble adenosine to inosine editing
J5W78_07335	COG1940	carbohydrate kinase activity
J5W78_07340	COG2217	Heavy metal translocating P-type atpase
J5W78_07350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5W78_07355	COG0237	dephospho-CoA kinase activity
J5W78_07385	COG1363	Peptidase, m42
J5W78_07390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5W78_07405	COG0006	proline dipeptidase activity
J5W78_07410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5W78_07450	COG0745	RESPONSE REGULATOR receiver
J5W78_07455	COG0129	dihydroxy-acid dehydratase activity
J5W78_07485	COG1368	sulfuric ester hydrolase activity
J5W78_07525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5W78_07530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5W78_07555	COG0534	Mate efflux family protein
J5W78_07560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5W78_07585	COG1881	PFAM PEBP family protein
J5W78_07615	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5W78_07620	COG1119	ATPase activity
J5W78_07625	COG2186	Transcriptional regulator
J5W78_07655	COG0148	phosphopyruvate hydratase activity
J5W78_07670	COG0436	Aminotransferase
J5W78_07685	COG3345	alpha-galactosidase
J5W78_07695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5W78_07710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5W78_07730	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5W78_07740	COG1199	ATP-dependent helicase activity
J5W78_07745	COG1122	ATPase activity
J5W78_07770	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W78_07775	COG0598	Magnesium transport protein CorA
J5W78_07780	COG0359	binds to the 23S rRNA
J5W78_07785	COG0138	bifunctional purine biosynthesis protein purh
J5W78_07790	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5W78_07795	COG0736	holo-[acyl-carrier-protein] synthase activity
J5W78_07815	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J5W78_07820	COG3409	Peptidoglycan-binding domain 1 protein
J5W78_07820	COG5632	N-Acetylmuramoyl-L-alanine amidase
J5W78_07825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5W78_07835	COG0437	4 iron, 4 sulfur cluster binding
J5W78_07860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5W78_07905	COG0284	orotidine-5'-phosphate decarboxylase activity
J5W78_07920	COG3568	Endonuclease Exonuclease Phosphatase
J5W78_07925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5W78_07930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5W78_07955	COG2003	Belongs to the UPF0758 family
J5W78_07960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5W78_07960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5W78_07965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5W78_07970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5W78_07975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5W78_07985	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5W78_07990	COG0322	excinuclease ABC activity
J5W78_07995	COG0811	peptide transport
J5W78_08000	COG0848	biopolymer transport protein
J5W78_08010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5W78_08015	COG0483	inositol monophosphate 1-phosphatase activity
J5W78_08020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5W78_08025	COG0706	membrane insertase activity
J5W78_08030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5W78_08040	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5W78_08050	COG0676	glucose-6-phosphate 1-epimerase activity
J5W78_08055	COG0259	pyridoxamine-phosphate oxidase activity
J5W78_08070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5W78_08080	COG1760	l-serine dehydratase
J5W78_08085	COG0492	ferredoxin-NADP+ reductase activity
J5W78_08085	COG3118	belongs to the thioredoxin family
J5W78_08135	COG1408	metallophosphoesterase
J5W78_08145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5W78_08150	COG0545	Peptidyl-prolyl cis-trans isomerase
J5W78_08165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5W78_08175	COG0826	peptidase U32
J5W78_08180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5W78_08210	COG0581	inorganic phosphate transmembrane transporter activity
J5W78_08215	COG0573	inorganic phosphate transmembrane transporter activity
J5W78_08235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5W78_08245	COG2017	converts alpha-aldose to the beta-anomer
J5W78_08260	COG0612	Peptidase, M16
J5W78_08270	COG0233	cytoplasmic translational termination
J5W78_08275	COG0528	UMP kinase activity
J5W78_08280	COG0668	transmembrane transport
J5W78_08290	COG0450	alkyl hydroperoxide reductase
J5W78_08295	COG0733	neurotransmitter:sodium symporter activity
J5W78_08315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5W78_08325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5W78_08335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5W78_08340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5W78_08355	COG2169	Transcriptional regulator
J5W78_08360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5W78_08370	COG0842	Transport permease protein
J5W78_08375	COG0842	Transport permease protein
J5W78_08380	COG1131	(ABC) transporter
J5W78_08390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5W78_08395	COG1183	phosphatidylcholine synthase activity
J5W78_08405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5W78_08435	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5W78_08440	COG1028	Short-chain dehydrogenase reductase Sdr
J5W78_08460	COG0156	8-amino-7-oxononanoate synthase activity
J5W78_08495	COG3209	COG3209 Rhs family protein
J5W78_08520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5W78_08525	COG0124	histidyl-tRNA synthetase
J5W78_08535	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5W78_08540	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
J5W78_08545	COG0298	carbon dioxide binding
J5W78_08565	COG0438	transferase activity, transferring glycosyl groups
J5W78_08570	COG0443	Heat shock 70 kDa protein
J5W78_08575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5W78_08580	COG0459	protein refolding
J5W78_08625	COG0632	four-way junction helicase activity
J5W78_08635	COG0126	phosphoglycerate kinase activity
J5W78_08645	COG1082	Xylose isomerase domain protein TIM barrel
J5W78_08655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5W78_08665	COG2271	Major facilitator Superfamily
J5W78_08670	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
J5W78_08680	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J5W78_08690	COG0037	tRNA processing
J5W78_08695	COG0254	rRNA binding
J5W78_08735	COG3969	phosphoadenosine phosphosulfate
J5W78_08820	COG0305	Participates in initiation and elongation during chromosome replication
J5W78_08935	COG1083	cytidylyl-transferase
J5W78_09015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5W78_09020	COG0039	L-malate dehydrogenase activity
J5W78_09040	COG0778	Nitroreductase
J5W78_09045	COG0564	pseudouridine synthase activity
J5W78_09060	COG1335	isochorismatase
J5W78_09090	COG1126	abc transporter atp-binding protein
J5W78_09095	COG0765	amino acid transport
J5W78_09100	COG1216	Glycosyl transferase, family 2
J5W78_09115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W78_09120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J5W78_09135	COG0489	protein tyrosine kinase activity
J5W78_09135	COG3206	protein involved in exopolysaccharide biosynthesis
J5W78_09140	COG0438	transferase activity, transferring glycosyl groups
J5W78_09150	COG1215	transferase activity, transferring glycosyl groups
J5W78_09175	COG0438	transferase activity, transferring glycosyl groups
J5W78_09180	COG1216	Glycosyl transferase, family 2
J5W78_09180	COG1442	glycosyl transferase family 8
J5W78_09185	COG0438	transferase activity, transferring glycosyl groups
J5W78_09190	COG1215	transferase activity, transferring glycosyl groups
J5W78_09195	COG0438	transferase activity, transferring glycosyl groups
J5W78_09200	COG1216	Glycosyl transferase, family 2
J5W78_09220	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5W78_09225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5W78_09245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W78_09290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5W78_09295	COG1872	DUF167
J5W78_09300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5W78_09305	COG0484	heat shock protein binding
J5W78_09310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5W78_09320	COG5434	Belongs to the glycosyl hydrolase 28 family
J5W78_09335	COG0277	FAD linked oxidase domain protein
J5W78_09360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5W78_09365	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5W78_09375	COG0131	Imidazoleglycerol-phosphate dehydratase
J5W78_09380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5W78_09390	COG0360	Binds together with S18 to 16S ribosomal RNA
J5W78_09400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5W78_09415	COG1686	Belongs to the peptidase S11 family
J5W78_09420	COG0205	6-phosphofructokinase activity
J5W78_09430	COG0428	transporter
J5W78_09435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5W78_09450	COG3977	Valine--pyruvate aminotransferase
J5W78_09455	COG1561	YicC-like family, N-terminal region
J5W78_09475	COG0471	metal ion transport
J5W78_09475	COG3273	potassium ion transport
J5W78_09480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W78_09495	COG1575	Belongs to the MenA family. Type 1 subfamily
J5W78_09530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W78_09530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5W78_09555	COG0202	RNA polymerase activity
J5W78_09560	COG0203	ribosomal protein L17
J5W78_09565	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5W78_09580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W78_09635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W78_09665	COG0667	Aldo Keto reductase
J5W78_09670	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5W78_09675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W78_09680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W78_09685	COG0134	indole-3-glycerol-phosphate synthase activity
J5W78_09690	COG0135	phosphoribosylanthranilate isomerase activity
J5W78_09695	COG0133	tryptophan synthase activity
J5W78_09700	COG0159	tryptophan synthase activity
J5W78_09725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5W78_09730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5W78_09750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J5W78_09780	COG0561	phosphatase activity
J5W78_09790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W78_09795	COG2223	nitrite transmembrane transporter activity
J5W78_09820	COG0556	nucleotide-excision repair
J5W78_09830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5W78_09835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5W78_09860	COG1074	ATP-dependent DNA helicase activity
J5W78_09870	COG0697	spore germination
J5W78_09875	COG2373	Large extracellular alpha-helical protein
J5W78_09880	COG1979	alcohol dehydrogenase
J5W78_09940	COG0372	Belongs to the citrate synthase family
J5W78_09945	COG3647	Membrane
J5W78_09950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J5W78_09960	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5W78_09970	COG1187	pseudouridine synthase activity
J5W78_09980	COG0105	UTP biosynthetic process
J5W78_09985	COG1215	transferase activity, transferring glycosyl groups
J5W78_09990	COG0463	Glycosyl transferase, family 2
J5W78_10000	COG1459	type II secretion system
J5W78_10005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W78_10010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J5W78_10030	COG3468	outer membrane autotransporter barrel domain protein
J5W78_10040	COG0728	peptidoglycan biosynthetic process
J5W78_10045	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W78_10045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W78_10055	COG1649	PFAM Uncharacterised BCR, COG1649
J5W78_10060	COG1691	(AIR) carboxylase
J5W78_10065	COG1606	tRNA processing
J5W78_10070	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
J5W78_10075	COG0142	geranyltranstransferase activity
J5W78_10090	COG1162	GTPase activity
J5W78_10110	COG2151	metal-sulfur cluster biosynthetic enzyme
J5W78_10130	COG1007	ATP synthesis coupled electron transport
J5W78_10135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W78_10145	COG0713	ATP synthesis coupled electron transport
J5W78_10150	COG0839	Belongs to the complex I subunit 6 family
J5W78_10160	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5W78_10165	COG1034	ATP synthesis coupled electron transport
J5W78_10170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5W78_10175	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5W78_10180	COG0649	NAD binding
J5W78_10185	COG0726	polysaccharide deacetylase
J5W78_10195	COG0307	riboflavin synthase, alpha
J5W78_10205	COG2264	protein methyltransferase activity
J5W78_10210	COG1640	4-alpha-glucanotransferase
J5W78_10220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5W78_10225	COG1030	water channel activity
J5W78_10230	COG0358	DNA primase activity
J5W78_10235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5W78_10240	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
J5W78_10265	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5W78_10270	COG0793	Belongs to the peptidase S41A family
J5W78_10280	COG1643	Atp-dependent helicase
J5W78_10305	COG1450	Type ii and iii secretion system protein
J5W78_10320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5W78_10345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5W78_10350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5W78_10360	COG0268	Binds directly to 16S ribosomal RNA
J5W78_10365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5W78_10370	COG0028	Belongs to the TPP enzyme family
J5W78_10390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5W78_10395	COG0495	leucyl-tRNA aminoacylation
J5W78_10400	COG3119	arylsulfatase activity
J5W78_10415	COG1166	arginine decarboxylase activity
J5W78_10425	COG3250	beta-galactosidase activity
J5W78_10430	COG3250	beta-galactosidase activity
J5W78_10435	COG3250	beta-galactosidase activity
J5W78_10440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5W78_10445	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_10455	COG1335	isochorismatase
J5W78_10465	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J5W78_10485	COG0205	6-phosphofructokinase activity
J5W78_10550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5W78_10555	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5W78_10560	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
J5W78_10570	COG4771	TonB-dependent receptor
J5W78_10575	COG0747	negative chemotaxis
J5W78_10590	COG0402	S-adenosylhomocysteine deaminase activity
J5W78_10595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5W78_10610	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5W78_10620	COG1294	oxidase, subunit
J5W78_10625	COG1271	oxidase subunit
J5W78_10635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5W78_10655	COG1846	Transcriptional regulator
J5W78_10695	COG2949	membrane
J5W78_10710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W78_10720	COG0489	protein tyrosine kinase activity
J5W78_10765	COG0438	transferase activity, transferring glycosyl groups
J5W78_10785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5W78_10785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W78_10815	COG0514	ATP-dependent DNA helicase (RecQ)
J5W78_10840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5W78_10845	COG0045	succinate-CoA ligase (ADP-forming) activity
J5W78_10850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5W78_10880	COG1570	exodeoxyribonuclease VII activity
J5W78_10905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5W78_10910	COG2205	protein histidine kinase activity
J5W78_10925	COG0113	porphobilinogen synthase activity
J5W78_10940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5W78_10960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5W78_10975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5W78_10990	COG4106	trans-aconitate 2-methyltransferase activity
J5W78_11005	COG3475	LICD family
J5W78_11010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5W78_11015	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5W78_11020	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W78_11025	COG3475	LICD family
J5W78_11030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5W78_11040	COG2166	iron-sulfur cluster assembly
J5W78_11045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5W78_11055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W78_11060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5W78_11065	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5W78_11070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5W78_11075	COG1131	(ABC) transporter
J5W78_11090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5W78_11105	COG1215	transferase activity, transferring glycosyl groups
J5W78_11115	COG2967	ApaG domain
J5W78_11120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5W78_11125	COG1522	sequence-specific DNA binding
J5W78_11130	COG0436	Aminotransferase
J5W78_11145	COG0423	glycine-tRNA ligase activity
J5W78_11175	COG1518	maintenance of DNA repeat elements
J5W78_11245	COG0586	Pfam SNARE associated Golgi protein
J5W78_11250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5W78_11255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5W78_11275	COG0038	chloride channel
J5W78_11290	COG4112	unkown
J5W78_11310	COG1538	Outer membrane efflux protein
J5W78_11320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W78_11330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5W78_11350	COG3209	COG3209 Rhs family protein
J5W78_11370	COG0489	protein tyrosine kinase activity
J5W78_11375	COG0534	Mate efflux family protein
J5W78_11405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5W78_11410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5W78_11425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5W78_11440	COG0418	dihydroorotase activity
J5W78_11445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5W78_11450	COG0513	Belongs to the DEAD box helicase family
J5W78_11455	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5W78_11480	COG2015	COG2015, Alkyl sulfatase and related hydrolases
J5W78_11490	COG1703	isobutyryl-CoA mutase activity
J5W78_11525	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5W78_11530	COG0352	thiamine-phosphate diphosphorylase activity
J5W78_11550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W78_11555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5W78_11560	COG0326	Molecular chaperone. Has ATPase activity
J5W78_11575	COG3059	membrane
J5W78_11590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W78_11590	COG0072	phenylalanine-tRNA ligase activity
J5W78_11605	COG3033	Beta-eliminating lyase
J5W78_11635	COG2818	Glycosylase
J5W78_11640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5W78_11675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W78_11675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5W78_11685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W78_11695	COG0166	Belongs to the GPI family
J5W78_11705	COG0574	Belongs to the PEP-utilizing enzyme family
J5W78_11705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5W78_11715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5W78_11725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5W78_11735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5W78_11750	COG5522	Integral membrane protein (intg_mem_TP0381)
J5W78_11775	COG0527	aspartate kinase activity
J5W78_11780	COG0460	homoserine dehydrogenase
J5W78_11790	COG3610	response to peptide
J5W78_11795	COG2966	Psort location CytoplasmicMembrane, score
J5W78_11800	COG1410	methionine synthase
J5W78_11800	COG0646	methionine synthase
J5W78_11840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5W78_11845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5W78_11845	COG0519	Catalyzes the synthesis of GMP from XMP
J5W78_11865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5W78_11865	COG0512	Glutamine amidotransferase of anthranilate synthase
J5W78_11870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5W78_11890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5W78_11900	COG3468	outer membrane autotransporter barrel domain protein
J5W78_11925	COG2195	Cleaves the N-terminal amino acid of tripeptides
J5W78_11930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5W78_11950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W78_11950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5W78_11965	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J5W78_11965	COG0037	tRNA processing
J5W78_11980	COG1247	-acetyltransferase
J5W78_12020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5W78_12030	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5W78_12035	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5W78_12035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5W78_12045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5W78_12055	COG1454	alcohol dehydrogenase
J5W78_12065	COG4974	Belongs to the 'phage' integrase family
J5W78_12090	COG1408	metallophosphoesterase
J5W78_12100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5W78_12115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5W78_12125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5W78_12140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5W78_12165	COG5002	protein histidine kinase activity
J5W78_12170	COG0745	RESPONSE REGULATOR receiver
J5W78_12185	COG1968	undecaprenyl-diphosphatase activity
J5W78_12190	COG0805	protein transport
J5W78_12195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5W78_12195	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J5W78_12205	COG0668	transmembrane transport
J5W78_12210	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5W78_12215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5W78_12220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5W78_12225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5W78_12230	COG0456	acetyltransferase
J5W78_12250	COG0538	isocitrate dehydrogenase activity
J5W78_12265	COG3258	Cytochrome c
J5W78_12310	COG0640	Transcriptional regulator
J5W78_12320	COG0242	peptide deformylase activity
J5W78_12330	COG0811	peptide transport
J5W78_12345	COG0151	Belongs to the GarS family
J5W78_12350	COG3738	Protein conserved in bacteria
J5W78_12355	COG2759	Belongs to the formate--tetrahydrofolate ligase family
J5W78_12360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J5W78_12380	COG0601	transmembrane transport
J5W78_12385	COG4239	(ABC) transporter, permease
J5W78_12395	COG0444	Belongs to the ABC transporter superfamily
J5W78_12400	COG4608	Belongs to the ABC transporter superfamily
J5W78_12405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5W78_12415	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J5W78_12425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5W78_12445	COG0697	spore germination
J5W78_12450	COG2132	Multicopper oxidase
J5W78_12455	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5W78_12460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_12480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5W78_12515	COG0738	Major facilitator superfamily
J5W78_12555	COG1741	Belongs to the pirin family
J5W78_12565	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5W78_12580	COG0363	glucosamine-6-phosphate deaminase activity
J5W78_12585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J5W78_12590	COG1837	Belongs to the UPF0109 family
J5W78_12615	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5W78_12655	COG0789	Transcriptional regulator
J5W78_12670	COG1408	metallophosphoesterase
J5W78_12680	COG0656	L-ascorbic acid biosynthetic process
J5W78_12695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W78_12705	COG0697	spore germination
J5W78_12710	COG2311	Membrane
J5W78_12720	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5W78_12740	COG2755	lipolytic protein G-D-S-L family
J5W78_12740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5W78_12940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_12945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5W78_12980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5W78_12985	COG0154	amidase activity
J5W78_12990	COG0714	Associated with various cellular activities
J5W78_13005	COG2304	oxidoreductase activity
J5W78_13020	COG0656	L-ascorbic acid biosynthetic process
J5W78_13025	COG0110	maltose O-acetyltransferase activity
J5W78_13035	COG2207	Transcriptional regulator
J5W78_13045	COG1012	belongs to the aldehyde dehydrogenase family
J5W78_13065	COG0753	catalase activity
J5W78_13090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5W78_13095	COG1592	Rubrerythrin
J5W78_13110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5W78_13125	COG4464	protein tyrosine phosphatase activity
J5W78_13135	COG0438	transferase activity, transferring glycosyl groups
J5W78_13140	COG0438	transferase activity, transferring glycosyl groups
J5W78_13150	COG0438	transferase activity, transferring glycosyl groups
J5W78_13185	COG0110	maltose O-acetyltransferase activity
J5W78_13195	COG1216	Glycosyl transferase, family 2
J5W78_13205	COG1216	Glycosyl transferase, family 2
J5W78_13250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J5W78_13260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W78_13260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5W78_13265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J5W78_13270	COG0280	phosphate acetyltransferase
J5W78_13270	COG0281	malic enzyme
J5W78_13290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5W78_13305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5W78_13310	COG0724	RNA recognition motif
J5W78_13320	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5W78_13325	COG1063	alcohol dehydrogenase
J5W78_13340	COG0714	Associated with various cellular activities
J5W78_13350	COG0193	aminoacyl-tRNA hydrolase activity
J5W78_13360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5W78_13375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5W78_13390	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J5W78_13405	COG0375	protein maturation
J5W78_13430	COG0778	Nitroreductase
J5W78_13435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5W78_13470	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W78_13470	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J5W78_13490	COG3525	Glycosyl hydrolase, family 20, catalytic domain
J5W78_13495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5W78_13500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5W78_13515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W78_13520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5W78_13550	COG0305	Participates in initiation and elongation during chromosome replication
J5W78_13765	COG0339	signal peptide processing
J5W78_13770	COG0110	maltose O-acetyltransferase activity
J5W78_13780	COG0018	arginyl-trna synthetase
J5W78_13815	COG4822	anaerobic cobalamin biosynthetic process
J5W78_13835	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
J5W78_13850	COG1797	cobyrinic acid a,c-diamide synthase activity
J5W78_13855	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J5W78_13905	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5W78_13950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5W78_13965	COG0653	protein targeting
J5W78_13970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5W78_13970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5W78_14000	COG0494	nUDIX hydrolase