locus-tag	class	description
AKKM5201_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AKKM5201_00010	ENOG4105CJ1	ABC, transporter
AKKM5201_00030	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
AKKM5201_00050	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AKKM5201_00055	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AKKM5201_00070	ENOG4105C1J	atp-dependent rna helicase
AKKM5201_00080	ENOG4105EPC	oxidoreductase
AKKM5201_00095	ENOG4108ISG	Major Facilitator
AKKM5201_00100	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKKM5201_00110	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
AKKM5201_00135	ENOG4108IAJ	Nad-dependent epimerase dehydratase
AKKM5201_00160	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AKKM5201_00195	ENOG4105E5D	amino acid
AKKM5201_00200	ENOG4105CSV	Glutaminase
AKKM5201_00215	ENOG4105BZG	amino acid carrier protein
AKKM5201_00225	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AKKM5201_00230	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AKKM5201_00235	ENOG4105C25	Primosomal protein n'
AKKM5201_00240	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AKKM5201_00260	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AKKM5201_00265	ENOG4107QJQ	Mate efflux family protein
AKKM5201_00340	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AKKM5201_00345	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AKKM5201_00355	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
AKKM5201_00370	ENOG4105DIK	(ABC) transporter
AKKM5201_00375	ENOG4105CC5	ABC transporter
AKKM5201_00380	ENOG4108Z0C	Uvrb UvrC protein
AKKM5201_00385	ENOG41066A3	ATP guanido phosphotransferase
AKKM5201_00390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AKKM5201_00405	ENOG4105ERH	Fumarylacetoacetate hydrolase
AKKM5201_00410	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AKKM5201_00425	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AKKM5201_00435	ENOG4105C31	Tryptophanyl-tRNA synthetase
AKKM5201_00445	ENOG4105D48	metallophosphoesterase
AKKM5201_00455	ENOG4105CUZ	uba thif-type nad fad binding protein
AKKM5201_00515	ENOG4106H6R	UPF0380 protein
AKKM5201_00590	ENOG4105D7K	pfkb domain protein
AKKM5201_00600	ENOG4105E09	nadh pyrophosphatase
AKKM5201_00610	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AKKM5201_00620	ENOG4107QJE	Chromosome Partitioning Protein
AKKM5201_00625	ENOG4107WDG	serine threonine protein kinase
AKKM5201_00880	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AKKM5201_00890	ENOG4105K78	MarR family Transcriptional regulator
AKKM5201_00895	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AKKM5201_00900	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AKKM5201_00910	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AKKM5201_00915	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AKKM5201_00920	ENOG41083ND	50S ribosomal protein L33
AKKM5201_00925	ENOG4105SCY	DNAK suppressor
AKKM5201_00930	ENOG4105DKQ	ROK family
AKKM5201_00935	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AKKM5201_00945	ENOG4105M6F	mutator MutT protein
AKKM5201_00950	ENOG4105CW7	secretion protein, HlyD family
AKKM5201_00955	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKKM5201_00960	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKKM5201_00965	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AKKM5201_00980	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AKKM5201_00990	ENOG4108R96	Methyltransferase, YaeB family
AKKM5201_00995	ENOG4105CD3	dihydroorotase
AKKM5201_01000	ENOG4105CXT	aspartate transcarbamylase
AKKM5201_01005	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
AKKM5201_01020	ENOG4105DZ0	fad dependent oxidoreductase
AKKM5201_01025	ENOG4105DWY	Agmatine deiminase
AKKM5201_01035	ENOG4105DZP	Membrane-associated zinc metalloprotease
AKKM5201_01045	ENOG41061MV	Arylsulfatase
AKKM5201_01055	ENOG4105CE1	Ferrous iron transport protein b
AKKM5201_01085	ENOG4105DF5	DNA topoisomerase IV, subunit A
AKKM5201_01120	ENOG4105FA0	parb-like partition protein
AKKM5201_01150	ENOG4105DHU	Bile acid
AKKM5201_01155	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AKKM5201_01175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AKKM5201_01180	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AKKM5201_01185	ENOG4107QSI	ABC, transporter
AKKM5201_01220	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AKKM5201_01225	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AKKM5201_01240	ENOG4105BZ1	(ABC) transporter
AKKM5201_01245	ENOG4105BZ1	(ABC) transporter
AKKM5201_01260	ENOG4105DHJ	ABC, transporter
AKKM5201_01265	ENOG4107PE3	Mammalian cell entry related domain protein
AKKM5201_01290	ENOG4105CZX	twitching motility protein
AKKM5201_01295	ENOG4105CZX	twitching motility protein
AKKM5201_01300	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AKKM5201_01315	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AKKM5201_01320	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AKKM5201_01325	ENOG4107RJ1	sodium solute
AKKM5201_01355	ENOG4108JQC	penicillin-binding protein 1A
AKKM5201_01365	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AKKM5201_01370	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AKKM5201_01380	ENOG4105D60	lipoprotein releasing system transmembrane protein
AKKM5201_01380	ENOG4105D60	lipoprotein releasing system transmembrane protein
AKKM5201_01390	ENOG4105CNA	YD repeat protein
AKKM5201_01440	ENOG4107VAM	peptidase, m28
AKKM5201_01450	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AKKM5201_01455	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AKKM5201_01470	ENOG4105C9B	Cysteine desulfurase
AKKM5201_01480	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
AKKM5201_01490	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AKKM5201_01500	ENOG4108ZVT	methylmalonyl-coA epimerase
AKKM5201_01505	ENOG4107QX3	carboxylase
AKKM5201_01515	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
AKKM5201_01520	ENOG4105D9Q	decarboxylase (Beta subunit)
AKKM5201_01525	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AKKM5201_01530	ENOG4105CYC	Transferase
AKKM5201_01545	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AKKM5201_01550	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AKKM5201_01555	ENOG4105CTQ	phosphohexokinase
AKKM5201_01565	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKKM5201_01570	ENOG4105C7K	acetolactate synthase
AKKM5201_01590	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AKKM5201_01595	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AKKM5201_01605	ENOG4105C8P	)-transporter
AKKM5201_01675	ENOG4105CHR	reductase
AKKM5201_01685	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AKKM5201_01690	ENOG4105CPQ	Dehydrogenase
AKKM5201_01700	ENOG4105EYW	Ion transport protein
AKKM5201_01705	ENOG41080E8	Transcriptional regulator, Spx MgsR family
AKKM5201_01710	ENOG4105CY0	Metallo-Beta-Lactamase
AKKM5201_01720	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AKKM5201_01730	ENOG4105FE9	pseudouridine synthase
AKKM5201_01740	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AKKM5201_01745	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AKKM5201_01755	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AKKM5201_01800	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AKKM5201_01805	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AKKM5201_01810	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AKKM5201_01815	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AKKM5201_01855	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKKM5201_02020	ENOG4105CDU	Replicative dna helicase
AKKM5201_02150	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
AKKM5201_02160	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AKKM5201_02180	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AKKM5201_02185	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AKKM5201_02190	ENOG4105K5M	30s ribosomal protein S16
AKKM5201_02215	ENOG4105VIE	preprotein translocase, subunit YajC
AKKM5201_02220	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AKKM5201_02225	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AKKM5201_02235	ENOG4105K6T	rare lipoprotein A
AKKM5201_02240	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AKKM5201_02245	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AKKM5201_02300	ENOG4105CNT	hydrolase family 2
AKKM5201_02305	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AKKM5201_02315	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AKKM5201_02320	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AKKM5201_02325	ENOG41082SA	50s ribosomal protein l29
AKKM5201_02330	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AKKM5201_02335	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AKKM5201_02340	ENOG41080P9	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AKKM5201_02350	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AKKM5201_02355	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKKM5201_02360	ENOG4108542	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AKKM5201_02365	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AKKM5201_02370	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AKKM5201_02375	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AKKM5201_02380	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AKKM5201_02385	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AKKM5201_02390	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AKKM5201_02400	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AKKM5201_02410	ENOG4105BZU	Histidine kinase
AKKM5201_02415	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AKKM5201_02430	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AKKM5201_02445	ENOG4108M8S	permease YjgP YjgQ family protein
AKKM5201_02450	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AKKM5201_02470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKKM5201_02480	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AKKM5201_02510	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AKKM5201_02525	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AKKM5201_02535	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AKKM5201_02540	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AKKM5201_02555	ENOG4108IPT	Naphthoate synthase
AKKM5201_02595	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AKKM5201_02610	ENOG4108IJ6	ABC transporter
AKKM5201_02620	ENOG4105EMU	Dehydrogenase
AKKM5201_02635	ENOG4108JUA	Transcriptional regulator
AKKM5201_02650	ENOG4105E2D	ec 3.2.1.52
AKKM5201_02665	ENOG4105CVK	Glutamate decarboxylase
AKKM5201_02675	ENOG4105C0B	DNA polymerase III (alpha subunit)
AKKM5201_02680	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AKKM5201_02685	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AKKM5201_02705	ENOG4105C37	(CBS) domain
AKKM5201_02710	ENOG4105C37	(CBS) domain
AKKM5201_02720	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AKKM5201_02725	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AKKM5201_02730	ENOG4108UW5	maltose o-acetyltransferase
AKKM5201_02755	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AKKM5201_02760	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AKKM5201_02780	ENOG4106855	Competence protein
AKKM5201_02795	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AKKM5201_02810	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AKKM5201_02815	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AKKM5201_02825	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AKKM5201_02850	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
AKKM5201_02855	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AKKM5201_02860	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AKKM5201_02865	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AKKM5201_02875	ENOG4108775	30S ribosomal protein S21
AKKM5201_02880	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AKKM5201_02895	ENOG4105C54	Major Facilitator superfamily
AKKM5201_02910	ENOG4105CX6	glutaminyL-tRNA synthetase
AKKM5201_02915	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AKKM5201_02920	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AKKM5201_02925	ENOG410803B	Involved in the transcription termination process (By similarity)
AKKM5201_02930	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKKM5201_02935	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AKKM5201_02940	ENOG4105CDU	Replicative dna helicase
AKKM5201_02955	ENOG4105CEV	competence damage-inducible protein
AKKM5201_02965	ENOG4108W0I	acetyltransferase
AKKM5201_02990	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AKKM5201_02995	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AKKM5201_03000	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKKM5201_03005	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AKKM5201_03020	ENOG4105C79	DNA protecting protein DprA
AKKM5201_03025	ENOG4105DZ1	carboxypeptidase
AKKM5201_03030	ENOG4105C3G	gtp-binding protein
AKKM5201_03035	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AKKM5201_03045	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKKM5201_03060	ENOG41061MV	Arylsulfatase
AKKM5201_03090	ENOG4105NQG	DoxX
AKKM5201_03095	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AKKM5201_03100	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AKKM5201_03105	ENOG4105EMN	RNA polymerase sigma factor
AKKM5201_03125	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AKKM5201_03145	ENOG4105CSR	polyphosphate kinase 2
AKKM5201_03150	ENOG4107EDW	L-fucose operon activator
AKKM5201_03165	ENOG4105C3J	Cysteine desulfurase
AKKM5201_03175	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AKKM5201_03190	ENOG4106H78	methyltransferase
AKKM5201_03205	ENOG4105CSR	polyphosphate kinase 2
AKKM5201_03220	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
AKKM5201_03230	ENOG4107XM9	(LipO)protein
AKKM5201_03235	ENOG4105K8N	protein family UPF0079, ATPase
AKKM5201_03240	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AKKM5201_03245	ENOG4105K46	50S ribosomal protein l27
AKKM5201_03250	ENOG4105G5W	regulator Fur family
AKKM5201_03255	ENOG4105C3K	feS assembly ATPase SufC
AKKM5201_03260	ENOG4105DIW	FeS assembly protein SUFB
AKKM5201_03265	ENOG4105JRK	feS assembly protein SufD
AKKM5201_03275	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AKKM5201_03280	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AKKM5201_03325	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AKKM5201_03345	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AKKM5201_03350	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AKKM5201_03355	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AKKM5201_03360	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AKKM5201_03365	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AKKM5201_03380	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AKKM5201_03390	ENOG4105CJN	penicillin-binding protein
AKKM5201_03430	ENOG4105D06	uba thif-type nad fad binding protein
AKKM5201_03435	ENOG4105C2X	Arabinose 5-phosphate isomerase
AKKM5201_03455	ENOG4105D7W	serine acetyltransferase
AKKM5201_03465	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AKKM5201_03470	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AKKM5201_03475	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AKKM5201_03480	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AKKM5201_03490	ENOG4107QPR	SAICAR synthetase
AKKM5201_03500	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AKKM5201_03505	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AKKM5201_03515	ENOG4105CN9	Peptidase m42 family protein
AKKM5201_03535	ENOG4105DFF	Rod shape-determining protein mreb
AKKM5201_03540	ENOG4105C03	ribonuclease
AKKM5201_03570	ENOG4109015	Biopolymer transport protein exbD tolR
AKKM5201_03585	ENOG4105CSM	endonuclease III
AKKM5201_03605	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AKKM5201_03610	ENOG41080R2	UPF0102 protein
AKKM5201_03620	ENOG4105C37	(CBS) domain
AKKM5201_03630	ENOG41082R9	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AKKM5201_03645	ENOG4105CDH	Citrulline--aspartate ligase
AKKM5201_03650	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AKKM5201_03660	ENOG4105CP7	Triose-phosphate isomerase
AKKM5201_03675	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AKKM5201_03695	ENOG41081UC	Inherit from COG: Competence protein
AKKM5201_03705	ENOG4105DXN	mazG family
AKKM5201_03725	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AKKM5201_03730	ENOG4107RAN	Peptidase, M16
AKKM5201_03750	ENOG4105WPN	DNA integration recombination invertion protein
AKKM5201_03755	ENOG4107R11	Transcriptional regulator
AKKM5201_03760	ENOG4105SYT	Methylenetetrahydrofolate reductase
AKKM5201_03785	ENOG4105DGA	Diaminopimelate dehydrogenase
AKKM5201_03790	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
AKKM5201_03810	ENOG4105C7B	Threonine dehydratase
AKKM5201_03815	ENOG4108Z03	MAF-like protein
AKKM5201_03820	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AKKM5201_03840	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AKKM5201_03850	ENOG4105CAT	Cytidine monophosphate kinase
AKKM5201_03860	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AKKM5201_03870	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AKKM5201_03880	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AKKM5201_03970	ENOG4105CGK	Exodeoxyribonuclease III
AKKM5201_03975	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AKKM5201_03990	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AKKM5201_03995	ENOG4107QRG	dna polymerase iii
AKKM5201_04025	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
AKKM5201_04045	ENOG4105W5A	BNR Asp-box repeat protein
AKKM5201_04110	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AKKM5201_04115	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AKKM5201_04120	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AKKM5201_04125	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_04160	ENOG4105E33	succinate dehydrogenase
AKKM5201_04200	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AKKM5201_04215	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AKKM5201_04220	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AKKM5201_04225	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
AKKM5201_04230	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AKKM5201_04250	ENOG4105D3Q	Sugar transferase
AKKM5201_04255	ENOG4105VFU	Rna-binding protein
AKKM5201_04275	ENOG4105IDI	abc transporter atp-binding protein
AKKM5201_04295	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AKKM5201_04300	ENOG4105CGK	Exodeoxyribonuclease III
AKKM5201_04305	ENOG4105CHV	Transcription elongation factor NusA
AKKM5201_04310	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AKKM5201_04315	ENOG41084NN	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AKKM5201_04320	ENOG4105ENH	Sulfatase
AKKM5201_04340	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_04345	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_04350	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_04360	ENOG4105C7S	Dehydrogenase
AKKM5201_04365	ENOG4105CE4	GlcNAc 6-P deacetylase
AKKM5201_04375	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AKKM5201_04410	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AKKM5201_04425	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AKKM5201_04430	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AKKM5201_04435	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AKKM5201_04440	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AKKM5201_04445	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AKKM5201_04450	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AKKM5201_04455	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AKKM5201_04460	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AKKM5201_04470	ENOG41082A0	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AKKM5201_04475	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AKKM5201_04480	ENOG4105K6T	rare lipoprotein A
AKKM5201_04485	ENOG4105CGH	5'-nucleotidase
AKKM5201_04490	ENOG4105C0D	helicase
AKKM5201_04495	ENOG410823G	oxidoreductase
AKKM5201_04510	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AKKM5201_04515	ENOG4105CFP	Peptidase U32
AKKM5201_04545	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AKKM5201_04555	ENOG4108WBT	adenosyltransferase
AKKM5201_04565	ENOG4105CZM	Major Facilitator
AKKM5201_04575	ENOG4105E0Y	RtcB Protein
AKKM5201_04600	ENOG4107QM5	aconitate hydratase
AKKM5201_04605	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
AKKM5201_04625	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKKM5201_04660	ENOG4105BZS	acriflavin resistance protein
AKKM5201_04665	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AKKM5201_04670	ENOG4108Z6Z	Transcriptional regulator
AKKM5201_04675	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AKKM5201_04680	ENOG4105CPP	Dehydrogenase, E1 component
AKKM5201_04715	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AKKM5201_04720	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AKKM5201_04725	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AKKM5201_04730	ENOG4105C59	p-type ATPase
AKKM5201_04740	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AKKM5201_04750	ENOG4105C8Y	Acetylornithine aminotransferase
AKKM5201_04755	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AKKM5201_04760	ENOG4105G6Z	alkaline phosphatase
AKKM5201_04770	ENOG4105E2D	ec 3.2.1.52
AKKM5201_04775	ENOG4105CN9	Peptidase m42 family protein
AKKM5201_04785	ENOG4108RAC	Rubrerythrin
AKKM5201_04830	ENOG4105C8P	)-transporter
AKKM5201_04845	ENOG4105D0C	transport protein
AKKM5201_04870	ENOG4105DME	alpha-galactosidase
AKKM5201_04875	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AKKM5201_04895	ENOG41082EK	Restriction modification system DNA (Specificity
AKKM5201_04915	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AKKM5201_04920	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AKKM5201_04930	ENOG4105EQI	Metal Dependent Phosphohydrolase
AKKM5201_04940	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AKKM5201_04945	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AKKM5201_04960	ENOG4105CH7	arginosuccinase
AKKM5201_04965	ENOG4105CHH	sulfate transporter
AKKM5201_04975	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AKKM5201_05025	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AKKM5201_05045	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AKKM5201_05050	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AKKM5201_05055	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AKKM5201_05065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AKKM5201_05070	ENOG4105C08	Histidine kinase
AKKM5201_05085	ENOG4105CNT	hydrolase family 2
AKKM5201_05095	ENOG4105F8V	Hydrolase, tatD family
AKKM5201_05125	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AKKM5201_05135	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AKKM5201_05140	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AKKM5201_05145	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AKKM5201_05155	ENOG4105C0H	protease
AKKM5201_05160	ENOG4108ZP8	Acetolactate synthase small subunit
AKKM5201_05165	ENOG4105CQ7	ATP-dependent helicase
AKKM5201_05185	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AKKM5201_05195	ENOG4105KVH	Transcriptional regulator
AKKM5201_05210	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AKKM5201_05220	ENOG4105CRK	lysyL-tRNA synthetase
AKKM5201_05230	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AKKM5201_05235	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AKKM5201_05250	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AKKM5201_05270	ENOG4105C0P	Mg chelatase subunit ChlI
AKKM5201_05285	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AKKM5201_05300	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
AKKM5201_05305	ENOG4105GTN	ParB Domain Protein Nuclease
AKKM5201_05315	ENOG4105KK6	nuclease
AKKM5201_05325	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
AKKM5201_05335	ENOG4105NAU	thioesterase Superfamily protein
AKKM5201_05340	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AKKM5201_05350	ENOG4105C5I	Dehydrogenase
AKKM5201_05355	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AKKM5201_05395	ENOG4107QWE	)-transporter
AKKM5201_05415	ENOG4105EXC	Acyl-transferase
AKKM5201_05435	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_05440	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AKKM5201_05460	ENOG4105DIN	metallophosphoesterase
AKKM5201_05475	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AKKM5201_05485	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AKKM5201_05495	ENOG4105X0D	Fimbrial protein
AKKM5201_05500	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AKKM5201_05530	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AKKM5201_05565	ENOG4107YVC	modification (methylase)
AKKM5201_05585	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AKKM5201_05590	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AKKM5201_05650	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKKM5201_05680	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AKKM5201_05685	ENOG4105CI3	gtp-binding protein typa
AKKM5201_05690	ENOG4107RCW	fructose-bisphosphate aldolase
AKKM5201_05695	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AKKM5201_05700	ENOG4105DSF	transport protein
AKKM5201_05710	ENOG4107RY6	amino acid
AKKM5201_05715	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AKKM5201_05725	ENOG4105DI5	UPF0365 protein
AKKM5201_05730	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AKKM5201_05740	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AKKM5201_05750	ENOG4105CDY	transcriptional regulatory protein
AKKM5201_05755	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AKKM5201_05760	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AKKM5201_05785	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AKKM5201_05790	ENOG4105HMI	Membrane
AKKM5201_05795	ENOG4105DUM	transcriptional regulator, lysR family
AKKM5201_05840	ENOG4105K63	Thioredoxin
AKKM5201_05850	ENOG4105C5S	asparaginyl-tRNA synthetase
AKKM5201_05875	ENOG4105UYK	outer membrane protein a
AKKM5201_05880	ENOG4105DFU	Cell wall formation (By similarity)
AKKM5201_05890	ENOG4108IUZ	ABC transporter
AKKM5201_05905	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AKKM5201_05915	ENOG4105CE9	30S ribosomal protein S2
AKKM5201_05920	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AKKM5201_05930	ENOG4108JQ7	(ABC) transporter
AKKM5201_05940	ENOG4105D49	3-dehydroquinate synthase
AKKM5201_05950	ENOG4105C0H	protease
AKKM5201_05960	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKKM5201_05965	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AKKM5201_05970	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AKKM5201_05975	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
AKKM5201_05980	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AKKM5201_05990	ENOG4105CPF	Cell wall formation (By similarity)
AKKM5201_05995	ENOG4105DFU	Cell wall formation (By similarity)
AKKM5201_06000	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AKKM5201_06005	ENOG4105CNI	cell division protein FtsW
AKKM5201_06015	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AKKM5201_06020	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AKKM5201_06025	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
AKKM5201_06030	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AKKM5201_06035	ENOG4105CJN	penicillin-binding protein
AKKM5201_06045	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AKKM5201_06050	ENOG4108V6E	Cell division protein mraZ
AKKM5201_06055	ENOG4105CY0	Metallo-Beta-Lactamase
AKKM5201_06060	ENOG4105EN6	Membrane
AKKM5201_06070	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AKKM5201_06075	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AKKM5201_06080	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_06105	ENOG4107SBE	Glycosyl transferase (Group 1
AKKM5201_06125	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AKKM5201_06155	ENOG4105CHR	reductase
AKKM5201_06170	ENOG4105C5H	ABC transporter
AKKM5201_06180	ENOG4105MS2	ribosomal subunit Interface protein
AKKM5201_06195	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
AKKM5201_06210	ENOG4105ENX	hydrolase
AKKM5201_06220	ENOG4107SET	aldo keto reductase
AKKM5201_06275	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AKKM5201_06280	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
AKKM5201_06320	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AKKM5201_06325	ENOG4105C5H	ABC transporter
AKKM5201_06330	ENOG410631K	Membrane
AKKM5201_06340	ENOG4105C8N	cysteinyl-tRNA synthetase
AKKM5201_06345	ENOG4105E2D	ec 3.2.1.52
AKKM5201_06350	ENOG4105CBG	Sulfatase
AKKM5201_06360	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AKKM5201_06385	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKKM5201_06390	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKKM5201_06395	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AKKM5201_06400	ENOG4107Z3D	50S ribosomal protein l10
AKKM5201_06405	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AKKM5201_06410	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AKKM5201_06415	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AKKM5201_06430	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AKKM5201_06440	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AKKM5201_06450	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AKKM5201_06455	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AKKM5201_06460	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKKM5201_06470	ENOG4105SYT	Methylenetetrahydrofolate reductase
AKKM5201_06490	ENOG4108IJF	Heavy metal efflux pump, CzcA
AKKM5201_06535	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AKKM5201_06540	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AKKM5201_06570	ENOG4105CBG	Sulfatase
AKKM5201_06575	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKKM5201_06585	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
AKKM5201_06595	ENOG4108IYU	L-aspartate oxidase
AKKM5201_06600	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AKKM5201_06665	ENOG4105CA0	peroxidase
AKKM5201_06670	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AKKM5201_06675	ENOG4108Z6B	deaminase
AKKM5201_06680	ENOG4105DKQ	ROK family
AKKM5201_06685	ENOG4105C59	p-type ATPase
AKKM5201_06690	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AKKM5201_06695	ENOG4105GVR	general secretion pathway protein D
AKKM5201_06725	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AKKM5201_06735	ENOG4107RAQ	aminopeptidase
AKKM5201_06740	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AKKM5201_06760	ENOG4105BZU	Histidine kinase
AKKM5201_06765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AKKM5201_06770	ENOG4105C01	Dihydroxy-acid dehydratase
AKKM5201_06840	ENOG4105E0M	Sulfatase
AKKM5201_06875	ENOG4105CMR	udp-glucose 4-epimerase
AKKM5201_06880	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AKKM5201_06905	ENOG4107QI1	Mate efflux family protein
AKKM5201_07060	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AKKM5201_07065	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AKKM5201_07070	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AKKM5201_07075	ENOG4105C08	Histidine kinase
AKKM5201_07095	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AKKM5201_07115	ENOG4105CPC	Aldo Keto reductase
AKKM5201_07120	ENOG4105V75	Transcriptional regulator
AKKM5201_07170	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKKM5201_07195	ENOG4105ECP	epimerase
AKKM5201_07210	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AKKM5201_07215	ENOG4105DKW	ABC transporter
AKKM5201_07220	ENOG4105C6F	GntR Family Transcriptional Regulator
AKKM5201_07235	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AKKM5201_07245	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AKKM5201_07250	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
AKKM5201_07255	ENOG4105CJ2	(LipO)protein
AKKM5201_07270	ENOG41085AM	50S ribosomal protein L28
AKKM5201_07280	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AKKM5201_07285	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AKKM5201_07295	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
AKKM5201_07300	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AKKM5201_07310	ENOG4105DVT	helicase
AKKM5201_07315	ENOG4108JJB	ABC transporter
AKKM5201_07340	ENOG4105CAS	nag kinase
AKKM5201_07350	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AKKM5201_07355	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AKKM5201_07360	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AKKM5201_07365	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AKKM5201_07375	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AKKM5201_07380	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
AKKM5201_07395	ENOG4107SFQ	iron-sulfur binding
AKKM5201_07415	ENOG4105D49	3-dehydroquinate synthase
AKKM5201_07470	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AKKM5201_07490	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AKKM5201_07495	ENOG4105C6E	dna polymerase iii
AKKM5201_07515	ENOG4105W5Q	DNA repair protein (RadC
AKKM5201_07520	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AKKM5201_07525	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AKKM5201_07530	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AKKM5201_07535	ENOG4108UJD	30S ribosomal protein S9
AKKM5201_07540	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AKKM5201_07545	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AKKM5201_07555	ENOG4109015	Biopolymer transport protein exbD tolR
AKKM5201_07565	ENOG4108JQC	penicillin-binding protein 1A
AKKM5201_07570	ENOG4105ECY	inositol monophosphatase
AKKM5201_07575	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AKKM5201_07585	ENOG4105DG6	mannose-6-phosphate isomerase
AKKM5201_07595	ENOG4105DFD	Na H antiporter
AKKM5201_07600	ENOG4105C30	Nad-dependent epimerase dehydratase
AKKM5201_07605	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AKKM5201_07610	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AKKM5201_07615	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AKKM5201_07625	ENOG4105CBC	glutamate synthase
AKKM5201_07630	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKKM5201_07635	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AKKM5201_07670	ENOG4105DSB	aldose 1-epimerase
AKKM5201_07675	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AKKM5201_07680	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AKKM5201_07690	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AKKM5201_07710	ENOG4105EJQ	L-serine dehydratase
AKKM5201_07715	ENOG4105C3M	thioredoxin reductase
AKKM5201_07765	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AKKM5201_07770	ENOG4105DIN	metallophosphoesterase
AKKM5201_07780	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AKKM5201_07785	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AKKM5201_07800	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AKKM5201_07805	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AKKM5201_07815	ENOG4105CFP	Peptidase U32
AKKM5201_07820	ENOG4105E6M	Sulphatase-modifying factor protein
AKKM5201_07840	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AKKM5201_07860	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AKKM5201_07865	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AKKM5201_07880	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AKKM5201_07885	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AKKM5201_07890	ENOG4105E2Z	phosphate ABC transporter (Permease
AKKM5201_07895	ENOG4105C8U	phosphate abc transporter
AKKM5201_07905	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AKKM5201_07915	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AKKM5201_07930	ENOG4105C1V	Peptidase, M16
AKKM5201_07970	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AKKM5201_07975	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AKKM5201_07985	ENOG4105D3R	alkyl hydroperoxide reductase
AKKM5201_07990	ENOG4105C8J	)-transporter
AKKM5201_08005	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AKKM5201_08015	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AKKM5201_08020	ENOG4105E0X	reductase
AKKM5201_08025	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AKKM5201_08045	ENOG4107QWP	ABC-2 type transporter
AKKM5201_08050	ENOG4107QWP	ABC-2 type transporter
AKKM5201_08055	ENOG4105CJ1	ABC, transporter
AKKM5201_08065	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AKKM5201_08070	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AKKM5201_08080	ENOG4105EEI	dihydropteroate synthase
AKKM5201_08090	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AKKM5201_08095	ENOG4105CHR	reductase
AKKM5201_08120	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AKKM5201_08145	ENOG4105C9M	aspartyl-trna synthetase
AKKM5201_08150	ENOG4105CUT	histidyl-tRNA synthetase
AKKM5201_08170	ENOG4105CQS	hydrogenase expression formation protein HypD
AKKM5201_08175	ENOG4105C45	hydrogenase expression formation protein (HypE)
AKKM5201_08195	ENOG4105CFG	Acts as a chaperone (By similarity)
AKKM5201_08200	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AKKM5201_08205	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AKKM5201_08240	ENOG4105D75	Capsular exopolysaccharide family
AKKM5201_08255	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AKKM5201_08265	ENOG4105BZA	Phosphoglycerate kinase
AKKM5201_08275	ENOG4105CGS	Alpha-glucosidase
AKKM5201_08280	ENOG4105D9P	serine threonine protein kinase
AKKM5201_08285	ENOG4105D9P	serine threonine protein kinase
AKKM5201_08290	ENOG4108JA2	transcriptioN-repair coupling factor
AKKM5201_08300	ENOG4105DJB	Major Facilitator Superfamily
AKKM5201_08315	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
AKKM5201_08320	ENOG4105C6K	Malic enzyme
AKKM5201_08325	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AKKM5201_08330	ENOG4105NRA	50s ribosomal protein l31 type b
AKKM5201_08365	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AKKM5201_08370	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AKKM5201_08395	ENOG4108RCM	Nitroreductase
AKKM5201_08400	ENOG4105C34	Pseudouridine synthase
AKKM5201_08405	ENOG4105I08	Pseudouridine synthase
AKKM5201_08430	ENOG4105CDA	abc transporter atp-binding protein
AKKM5201_08515	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AKKM5201_08520	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AKKM5201_08570	ENOG4105VZ9	UPF0235 protein
AKKM5201_08575	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKKM5201_08580	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AKKM5201_08585	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AKKM5201_08595	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
AKKM5201_08610	ENOG4105CQB	FAD linked oxidase domain protein
AKKM5201_08635	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AKKM5201_08640	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AKKM5201_08650	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AKKM5201_08655	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AKKM5201_08660	ENOG4107Q5Z	Binds together with S18 to 16S ribosomal RNA (By similarity)
AKKM5201_08665	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AKKM5201_08680	ENOG4105DZ1	carboxypeptidase
AKKM5201_08685	ENOG4105CTQ	phosphohexokinase
AKKM5201_08695	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
AKKM5201_08700	ENOG4105MH8	Thioredoxin disulfide isomerase
AKKM5201_08715	ENOG4105JKW	Valine--pyruvate aminotransferase
AKKM5201_08720	ENOG4105DSJ	YicC domain protein
AKKM5201_08735	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AKKM5201_08750	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AKKM5201_08770	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AKKM5201_08780	ENOG4108ZJ4	polysaccharide deacetylase
AKKM5201_08785	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AKKM5201_08795	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AKKM5201_08805	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AKKM5201_08810	ENOG4108ZT0	50S ribosomal protein l17
AKKM5201_08815	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AKKM5201_08825	ENOG4107YBY	Hydrolase
AKKM5201_08840	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AKKM5201_08905	ENOG4105CPC	Aldo Keto reductase
AKKM5201_08910	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AKKM5201_08930	ENOG4105CRQ	synthase (Component I)
AKKM5201_08935	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AKKM5201_08940	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AKKM5201_08945	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AKKM5201_08950	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AKKM5201_08955	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AKKM5201_08970	ENOG4105DWV	Homoserine O-trans-acetylase
AKKM5201_08975	ENOG4105YK5	50S ribosomal protein L36
AKKM5201_08985	ENOG4105F1A	Pyruvate formate-lyase
AKKM5201_09020	ENOG410667J	hydrolase
AKKM5201_09025	ENOG4108HCJ	Hydrolase
AKKM5201_09030	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AKKM5201_09085	ENOG4106H6R	UPF0380 protein
AKKM5201_09140	ENOG4105YB8	TM2 domain containing protein
AKKM5201_09160	ENOG4105D9P	serine threonine protein kinase
AKKM5201_09175	ENOG4107R3N	Filamentation induced by cAMP protein fic
AKKM5201_09205	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AKKM5201_09210	ENOG4105VJV	50s ribosomal protein L35
AKKM5201_09215	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AKKM5201_09235	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AKKM5201_09245	ENOG410631K	Membrane
AKKM5201_09255	ENOG4105D85	methylase
AKKM5201_09260	ENOG4105F6A	helicase
AKKM5201_09265	ENOG4105ECI	YeeC-like protein
AKKM5201_09270	ENOG4107S85	alpha-2-macroglobulin domain protein
AKKM5201_09275	ENOG4107QW4	alcohol dehydrogenase
AKKM5201_09290	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AKKM5201_09315	ENOG4105BZN	citrate synthase
AKKM5201_09335	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AKKM5201_09345	ENOG4108R99	pseudouridine synthase
AKKM5201_09355	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AKKM5201_09365	ENOG4105CKK	Glycosyl transferase, family 2
AKKM5201_09375	ENOG4105D7Q	type ii secretion system
AKKM5201_09380	ENOG4107QHF	type ii secretion system protein e
AKKM5201_09385	ENOG4107QHF	type ii secretion system protein e
AKKM5201_09390	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AKKM5201_09405	ENOG4105CJR	Integral membrane protein (MviN
AKKM5201_09410	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AKKM5201_09425	ENOG4105F32	YngK protein
AKKM5201_09430	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AKKM5201_09440	ENOG4105C8M	UPF0272 protein
AKKM5201_09445	ENOG4105EAH	synthase
AKKM5201_09460	ENOG4105VG1	fes assembly suf system protein
AKKM5201_09475	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKKM5201_09480	ENOG4105C8S	subunit m
AKKM5201_09490	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKKM5201_09495	ENOG4107UFS	subunit j
AKKM5201_09505	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AKKM5201_09510	ENOG4108IEH	NADH dehydrogenase subunit g
AKKM5201_09515	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
AKKM5201_09520	ENOG4105GKE	subunit e
AKKM5201_09525	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKKM5201_09530	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AKKM5201_09540	ENOG4108R6K	riboflavin synthase, subunit alpha
AKKM5201_09550	ENOG4107BJW	polysaccharide deacetylase
AKKM5201_09570	ENOG4107S1W	4-alpha-glucanotransferase
AKKM5201_09580	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AKKM5201_09585	ENOG4105F7J	membrane-bound serine protease
AKKM5201_09590	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AKKM5201_09595	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AKKM5201_09600	ENOG4108UQS	dipeptidase
AKKM5201_09615	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AKKM5201_09620	ENOG4105CN1	protease
AKKM5201_09635	ENOG4105CQ7	ATP-dependent helicase
AKKM5201_09660	ENOG4105GVR	general secretion pathway protein D
AKKM5201_09675	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AKKM5201_09695	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AKKM5201_09700	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AKKM5201_09710	ENOG410872P	Binds directly to 16S ribosomal RNA (By similarity)
AKKM5201_09715	ENOG4107VXZ	Hydrolase
AKKM5201_09720	ENOG4105C7K	acetolactate synthase
AKKM5201_09740	ENOG4105C8T	Leucyl-tRNA synthetase
AKKM5201_09745	ENOG4105ENH	Sulfatase
AKKM5201_09760	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AKKM5201_09775	ENOG4105CNT	hydrolase family 2
AKKM5201_09780	ENOG4105CNT	hydrolase family 2
AKKM5201_09785	ENOG4105D1H	recombination factor protein RarA
AKKM5201_09790	ENOG4105E2D	ec 3.2.1.52
AKKM5201_09810	ENOG4105CTQ	phosphohexokinase
AKKM5201_09845	ENOG4108YZT	Adenosylcobinamide kinase
AKKM5201_09855	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AKKM5201_09860	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AKKM5201_09865	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AKKM5201_09870	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AKKM5201_09880	ENOG4107ENK	receptor
AKKM5201_09900	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AKKM5201_09905	ENOG4107QN2	dihydrolipoyl dehydrogenase
AKKM5201_09925	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AKKM5201_09930	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AKKM5201_09940	ENOG4107WAU	Protein tyrosine phosphatase
AKKM5201_09960	ENOG410834F	Transcriptional regulator
AKKM5201_09990	ENOG4108UB4	uncharacterized protein ygjQ
AKKM5201_10020	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AKKM5201_10035	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AKKM5201_10040	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AKKM5201_10045	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AKKM5201_10085	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AKKM5201_10090	ENOG4105CEY	Amp-dependent synthetase and ligase
AKKM5201_10115	ENOG4108IAJ	Nad-dependent epimerase dehydratase
AKKM5201_10120	ENOG41065SU	Two-component system sensor kinase
AKKM5201_10135	ENOG4105D52	delta-aminolevulinic acid dehydratase
AKKM5201_10150	ENOG4105C22	threonyL-tRNA synthetase
AKKM5201_10155	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AKKM5201_10185	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AKKM5201_10220	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
AKKM5201_10235	ENOG4105KPE	licD family
AKKM5201_10240	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
AKKM5201_10250	ENOG4105KPE	licD family
AKKM5201_10270	ENOG4105KPE	licD family
AKKM5201_10275	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AKKM5201_10285	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AKKM5201_10290	ENOG4105DBV	ornithine carbamoyltransferase
AKKM5201_10295	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AKKM5201_10300	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
AKKM5201_10305	ENOG41080Z8	PHOSPHOCARRIER protein
AKKM5201_10310	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
AKKM5201_10315	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AKKM5201_10320	ENOG4105DA5	(ABC) transporter
AKKM5201_10335	ENOG4105DFA	alanine racemase domain protein
AKKM5201_10350	ENOG4105CND	Glycosyl transferase, family 2
AKKM5201_10365	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AKKM5201_10365	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AKKM5201_10380	ENOG4108ZB6	transcriptional regulator AsnC family
AKKM5201_10385	ENOG4105CHM	Aminotransferase
AKKM5201_10400	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AKKM5201_10405	ENOG4105CV8	reductase
AKKM5201_10435	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKKM5201_10440	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AKKM5201_10445	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AKKM5201_10485	ENOG4105C0H	protease
AKKM5201_10500	ENOG4105EXC	Acyl-transferase
AKKM5201_10520	ENOG4105C87	Aminotransferase class I and II
AKKM5201_10530	ENOG4105CV8	reductase
AKKM5201_10535	ENOG4105ENX	hydrolase
AKKM5201_10540	ENOG4107SET	aldo keto reductase
AKKM5201_10545	ENOG4105DIN	metallophosphoesterase
AKKM5201_10565	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
AKKM5201_10570	ENOG4105VUF	Transcriptional regulator
AKKM5201_10590	ENOG4105C3S	Mate efflux family protein
AKKM5201_10600	ENOG4105E2D	ec 3.2.1.52
AKKM5201_10615	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AKKM5201_10630	ENOG4105VB6	UPF0109 protein
AKKM5201_10640	ENOG4105DR4	Methyltransferase
AKKM5201_10645	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AKKM5201_10660	ENOG4105DX0	Hemolysin A
AKKM5201_10680	ENOG4105C2I	pirin domain protein
AKKM5201_10700	ENOG4105CMG	Carbohydrate kinase
AKKM5201_10710	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
AKKM5201_10715	ENOG4105EDR	glucose galactose transporter
AKKM5201_10750	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AKKM5201_10770	ENOG4105C0H	protease
AKKM5201_10780	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AKKM5201_10790	ENOG4105E3B	Multicopper oxidase
AKKM5201_10795	ENOG4105EMK	carboxylate amino acid amine transporter
AKKM5201_10810	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AKKM5201_10815	ENOG4108JQ7	(ABC) transporter
AKKM5201_10825	ENOG4108J59	Extracellular solute-binding protein, family 5
AKKM5201_10830	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AKKM5201_10850	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AKKM5201_10855	ENOG4105CKU	formyltetrahydrofolate synthetase
AKKM5201_10860	ENOG4108XC3	NADH ubiquinone oxidoreductase
AKKM5201_10875	ENOG4107QNG	Phosphoribosylglycinamide synthetase
AKKM5201_10900	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AKKM5201_10940	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AKKM5201_10950	ENOG4105NQN	cytochrome C
AKKM5201_10965	ENOG4105MEV	Acyl-transferase
AKKM5201_10970	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AKKM5201_10990	ENOG4105CY0	Metallo-Beta-Lactamase
AKKM5201_10995	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AKKM5201_11000	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AKKM5201_11010	ENOG4105D64	Mechanosensitive ion channel
AKKM5201_11015	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AKKM5201_11020	ENOG410845M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes (By similarity)
AKKM5201_11025	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AKKM5201_11045	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AKKM5201_11055	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AKKM5201_11065	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AKKM5201_11075	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AKKM5201_11085	ENOG4105DIN	metallophosphoesterase
AKKM5201_11105	ENOG4105DVP	Adenine-specific
AKKM5201_11110	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AKKM5201_11130	ENOG4108JB8	alcohol dehydrogenase
AKKM5201_11155	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AKKM5201_11170	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AKKM5201_11190	ENOG4105E2D	ec 3.2.1.52
AKKM5201_11195	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AKKM5201_11200	ENOG4105CBG	Sulfatase
AKKM5201_11210	ENOG4105CRE	cytochrome C
AKKM5201_11225	ENOG4108IPW	abc transporter atp-binding protein
AKKM5201_11230	ENOG4105CM4	permease protein
AKKM5201_11235	ENOG4105DHS	permease protein
AKKM5201_11270	ENOG4105C2M	dna polymerase I
AKKM5201_11285	ENOG4105C83	adenylosuccinate lyase
AKKM5201_11290	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AKKM5201_11350	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AKKM5201_11355	ENOG4108Z66	YbaK ebsC protein
AKKM5201_11395	ENOG4105C3R	Methionine synthase
AKKM5201_11400	ENOG4105DWK	Membrane
AKKM5201_11405	ENOG4107XM3	UPF0442 protein
AKKM5201_11420	ENOG4105CFH	Aspartokinase
AKKM5201_11445	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AKKM5201_11450	ENOG4105E2X	shikimate dehydrogenase
AKKM5201_11460	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AKKM5201_11465	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AKKM5201_11475	ENOG4107QP8	phosphohexose isomerase
AKKM5201_11485	ENOG4105DR4	Methyltransferase
AKKM5201_11495	ENOG4105D5P	Methylmalonyl-coA mutase
AKKM5201_11535	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AKKM5201_11555	ENOG4105C0F	tryptophanase EC 4.1.99.1
AKKM5201_11570	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AKKM5201_11590	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AKKM5201_11610	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
AKKM5201_11625	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AKKM5201_11630	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AKKM5201_11645	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AKKM5201_11650	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AKKM5201_11665	ENOG4105E2D	ec 3.2.1.52
AKKM5201_11670	ENOG4105E2D	ec 3.2.1.52
AKKM5201_11675	ENOG4105DJT	lAO AO transport system ATPase
AKKM5201_11695	ENOG41081ID	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AKKM5201_11700	ENOG4105C1J	atp-dependent rna helicase
AKKM5201_11705	ENOG4105C5X	domain protein
AKKM5201_11710	ENOG4105EKE	dihydroorotase
AKKM5201_11725	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AKKM5201_11735	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AKKM5201_11745	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AKKM5201_11750	ENOG4107QSA	Oxaloacetate decarboxylase
AKKM5201_11760	ENOG4107QI1	Mate efflux family protein
AKKM5201_11780	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AKKM5201_11785	ENOG4105DGW	oligopeptidase A
AKKM5201_11790	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AKKM5201_11800	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AKKM5201_11815	ENOG4105U6W	MutT NUDIX family protein
AKKM5201_11845	ENOG4105D82	Glutamate dehydrogenase
AKKM5201_11855	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AKKM5201_11860	ENOG4107T5V	SNARE associated Golgi
AKKM5201_11935	ENOG4105C26	Dehydrogenase
AKKM5201_11955	ENOG4105CH6	catalase
AKKM5201_11970	ENOG4105CRE	cytochrome C
AKKM5201_11975	ENOG4108RAC	Rubrerythrin
AKKM5201_11985	ENOG41068WN	
AKKM5201_11995	ENOG4105CNU	cell division protein FtsK
AKKM5201_12015	ENOG4108QV3	biosynthesis protein
AKKM5201_12025	ENOG4105D3Q	Sugar transferase
AKKM5201_12035	ENOG4107XU6	Glycosyl transferase (Group 1
AKKM5201_12045	ENOG4105E2K	Glycosyl transferase (Group 1
AKKM5201_12075	ENOG4105CPK	Glycosyl transferase (Group 1
AKKM5201_12085	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
AKKM5201_12095	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_12100	ENOG4105K64	Glycosyl transferase, family 2
AKKM5201_12130	ENOG4105EXC	Acyl-transferase
AKKM5201_12150	ENOG4105C87	Aminotransferase class I and II
AKKM5201_12160	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AKKM5201_12165	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AKKM5201_12170	ENOG4105C6K	Malic enzyme
AKKM5201_12190	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AKKM5201_12240	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AKKM5201_12245	ENOG4105CPQ	Dehydrogenase
AKKM5201_12260	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AKKM5201_12270	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AKKM5201_12275	ENOG4105BZ4	penicillin-binding protein
AKKM5201_12290	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AKKM5201_12305	ENOG4105E3S	small subunit
AKKM5201_12310	ENOG4105DPX	Hydrogenase, large subunit
AKKM5201_12320	ENOG4108USZ	hydrogenase
AKKM5201_12325	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AKKM5201_12350	ENOG4108RCM	Nitroreductase
AKKM5201_12355	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AKKM5201_12375	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AKKM5201_12385	ENOG4107GFK	fumarate
AKKM5201_12405	ENOG4105E2D	ec 3.2.1.52
AKKM5201_12415	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AKKM5201_12425	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AKKM5201_12430	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AKKM5201_12445	ENOG4105CEY	Amp-dependent synthetase and ligase
AKKM5201_12475	ENOG4105DGW	oligopeptidase A
AKKM5201_12485	ENOG4105C75	arginyL-tRNA synthetase
AKKM5201_12520	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AKKM5201_12525	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AKKM5201_12530	ENOG4107QZM	n-acetylglutamate synthase
AKKM5201_12540	ENOG4108YZ4	nudix hydrolase