locus-tag	class	description
DMI73_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMI73_00010	COG1131	(ABC) transporter
DMI73_00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMI73_00035	COG0564	pseudouridine synthase activity
DMI73_00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMI73_00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMI73_00065	COG0513	Belongs to the DEAD box helicase family
DMI73_00075	COG0673	inositol 2-dehydrogenase activity
DMI73_00095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DMI73_00115	COG1971	Probably functions as a manganese efflux pump
DMI73_00145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI73_00170	COG0442	prolyl-tRNA aminoacylation
DMI73_00200	COG0531	amino acid
DMI73_00205	COG2066	Belongs to the glutaminase family
DMI73_00215	COG1115	amino acid carrier protein
DMI73_00225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMI73_00230	COG2890	protein-(glutamine-N5) methyltransferase activity
DMI73_00235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMI73_00240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMI73_00260	COG2226	methyltransferase
DMI73_00265	COG0534	Mate efflux family protein
DMI73_00335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI73_00340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DMI73_00345	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_00365	COG1121	(ABC) transporter
DMI73_00370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMI73_00375	COG3880	PFAM UvrB UvrC protein
DMI73_00380	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DMI73_00385	COG0542	response to heat
DMI73_00400	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMI73_00405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI73_00420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI73_00420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMI73_00435	COG0180	Tryptophanyl-tRNA synthetase
DMI73_00445	COG1692	metallophosphoesterase
DMI73_00455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DMI73_00470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMI73_00475	COG2816	NAD+ diphosphatase activity
DMI73_00485	COG0156	8-amino-7-oxononanoate synthase activity
DMI73_00505	COG3266	domain, Protein
DMI73_00505	COG0515	serine threonine protein kinase
DMI73_00695	COG1598	PFAM Uncharacterised protein family UPF0150
DMI73_00775	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMI73_00795	COG0732	type I restriction modification DNA specificity domain
DMI73_00800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DMI73_00805	COG3189	MarR family transcriptional regulator
DMI73_00815	COG0181	hydroxymethylbilane synthase activity
DMI73_00820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMI73_00830	COG1469	GTP cyclohydrolase I activity
DMI73_00835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMI73_00840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMI73_00845	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMI73_00850	COG1940	carbohydrate kinase activity
DMI73_00865	COG0494	nUDIX hydrolase
DMI73_00870	COG1566	PFAM secretion protein HlyD family protein
DMI73_00875	COG0577	efflux transmembrane transporter activity
DMI73_00875	COG1136	(ABC) transporter
DMI73_00880	COG1136	(ABC) transporter
DMI73_00880	COG0577	efflux transmembrane transporter activity
DMI73_00885	COG1538	Outer membrane efflux protein
DMI73_00900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI73_00915	COG1720	tRNA m6t6A37 methyltransferase activity
DMI73_00920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMI73_00925	COG0540	Belongs to the ATCase OTCase family
DMI73_00930	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMI73_00945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DMI73_00950	COG2957	Belongs to the agmatine deiminase family
DMI73_00960	COG0750	zinc metalloprotease
DMI73_00970	COG3119	arylsulfatase activity
DMI73_00980	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI73_00980	COG1918	ferrous iron import across plasma membrane
DMI73_01045	COG1475	DNA binding
DMI73_01095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMI73_01100	COG0601	transmembrane transport
DMI73_01165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMI73_01170	COG1132	(ABC) transporter
DMI73_01175	COG1132	(ABC) transporter
DMI73_01190	COG1127	ABC transporter
DMI73_01195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMI73_01225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMI73_01240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DMI73_01245	COG0504	CTP synthase activity
DMI73_01250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMI73_01275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI73_01285	COG1322	Protein conserved in bacteria
DMI73_01290	COG0546	phosphoglycolate phosphatase activity
DMI73_01295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI73_01305	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI73_01330	COG0657	acetylesterase activity
DMI73_01330	COG2755	lipolytic protein G-D-S-L family
DMI73_01335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMI73_01355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMI73_01375	COG0335	large ribosomal subunit rRNA binding
DMI73_01385	COG0346	lactoylglutathione lyase activity
DMI73_01400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMI73_01405	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DMI73_01410	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DMI73_01410	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DMI73_01415	COG0427	acetyl-CoA hydrolase
DMI73_01425	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMI73_01435	COG0205	6-phosphofructokinase activity
DMI73_01445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI73_01450	COG0028	Belongs to the TPP enzyme family
DMI73_01485	COG0471	metal ion transport
DMI73_01495	COG0351	phosphomethylpyrimidine kinase
DMI73_01560	COG0242	peptide deformylase activity
DMI73_01565	COG1063	alcohol dehydrogenase
DMI73_01575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMI73_01580	COG1393	Belongs to the ArsC family
DMI73_01585	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI73_01595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMI73_01605	COG1187	pseudouridine synthase activity
DMI73_01615	COG0336	Belongs to the RNA methyltransferase TrmD family
DMI73_01620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMI73_01630	COG0539	negative regulation of cytoplasmic translation
DMI73_01680	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMI73_01685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMI73_01690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMI73_01695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI73_01735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI73_01760	COG0662	Cupin 2, conserved barrel domain protein
DMI73_01760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMI73_01775	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMI73_01785	COG0537	adenosine 5'-monophosphoramidase activity
DMI73_01790	COG0009	L-threonylcarbamoyladenylate synthase
DMI73_01795	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMI73_01800	COG0228	four-way junction DNA binding
DMI73_01820	COG1862	Preprotein translocase
DMI73_01825	COG0343	queuine tRNA-ribosyltransferase activity
DMI73_01830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMI73_01840	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMI73_01845	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMI73_01850	COG0776	regulation of translation
DMI73_01885	COG0811	peptide transport
DMI73_01905	COG3250	beta-galactosidase activity
DMI73_01910	COG0525	valine-tRNA ligase activity
DMI73_01925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMI73_01930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMI73_01935	COG0255	Belongs to the universal ribosomal protein uL29 family
DMI73_01940	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMI73_01945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMI73_01950	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMI73_01960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMI73_01965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMI73_01970	COG0089	rRNA binding
DMI73_01975	COG0088	Forms part of the polypeptide exit tunnel
DMI73_01980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMI73_01985	COG0051	transcription antitermination factor activity, RNA binding
DMI73_01990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMI73_01995	COG0049	tRNA binding
DMI73_02000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMI73_02020	COG3852	Histidine kinase
DMI73_02025	COG2204	response regulator
DMI73_02035	COG1722	exodeoxyribonuclease VII activity
DMI73_02040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI73_02055	COG0795	lipopolysaccharide-transporting ATPase activity
DMI73_02060	COG1160	GTP binding
DMI73_02065	COG0444	Belongs to the ABC transporter superfamily
DMI73_02085	COG1136	(ABC) transporter
DMI73_02085	COG0577	efflux transmembrane transporter activity
DMI73_02095	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI73_02145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMI73_02155	COG0799	negative regulation of ribosome biogenesis
DMI73_02160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMI73_02220	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DMI73_02235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DMI73_02245	COG0300	oxidoreductase activity
DMI73_02265	COG0038	chloride channel
DMI73_02275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_02295	COG0076	glutamate decarboxylase activity
DMI73_02310	COG0167	dihydroorotate dehydrogenase activity
DMI73_02315	COG0352	thiamine-phosphate diphosphorylase activity
DMI73_02335	COG1253	flavin adenine dinucleotide binding
DMI73_02340	COG1253	flavin adenine dinucleotide binding
DMI73_02350	COG1185	polyribonucleotide nucleotidyltransferase activity
DMI73_02355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMI73_02360	COG0110	maltose O-acetyltransferase activity
DMI73_02385	COG0101	tRNA pseudouridine synthase activity
DMI73_02390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMI73_02410	COG4968	Prepilin-type N-terminal cleavage methylation domain
DMI73_02425	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_02430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMI73_02450	COG1136	(ABC) transporter
DMI73_02455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMI73_02465	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI73_02490	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_02495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMI73_02500	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMI73_02515	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DMI73_02520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMI73_02535	COG2814	Major facilitator Superfamily
DMI73_02555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI73_02560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI73_02560	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI73_02565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMI73_02570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMI73_02575	COG0552	protein localization to endoplasmic reticulum
DMI73_02580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMI73_02600	COG1058	Belongs to the CinA family
DMI73_02600	COG1546	Belongs to the CinA family
DMI73_02610	COG0456	acetyltransferase
DMI73_02635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMI73_02640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMI73_02645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMI73_02650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI73_02665	COG0758	DNA mediated transformation
DMI73_02670	COG1686	Belongs to the peptidase S11 family
DMI73_02675	COG0012	GTP binding
DMI73_02680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMI73_02690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI73_02690	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI73_02705	COG3119	arylsulfatase activity
DMI73_02735	COG2259	Doxx family
DMI73_02740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMI73_02770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI73_02790	COG2326	polyphosphate kinase activity
DMI73_02795	COG1349	DNA-binding transcription factor activity
DMI73_02810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI73_02815	COG1162	GTPase activity
DMI73_02830	COG0742	ribosomal rna small subunit methyltransferase
DMI73_02845	COG2326	polyphosphate kinase activity
DMI73_02860	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI73_02870	COG1073	alpha beta
DMI73_02875	COG0802	atpase or kinase
DMI73_02880	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMI73_02885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMI73_02890	COG0735	belongs to the Fur family
DMI73_02895	COG0396	ATPase activity
DMI73_02900	COG0719	Fe-S assembly protein
DMI73_02905	COG0719	Fe-S assembly protein
DMI73_02920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMI73_02960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMI73_02980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMI73_02985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMI73_02990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMI73_02995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMI73_03000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMI73_03005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMI73_03015	COG0356	it plays a direct role in the translocation of protons across the membrane
DMI73_03070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMI73_03095	COG1045	serine acetyltransferase
DMI73_03100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMI73_03105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMI73_03110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMI73_03120	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMI73_03130	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMI73_03135	COG0047	phosphoribosylformylglycinamidine synthase activity
DMI73_03145	COG1363	Peptidase, m42
DMI73_03160	COG1077	Cell shape determining protein MreB Mrl
DMI73_03165	COG1530	ribonuclease E activity
DMI73_03195	COG0848	biopolymer transport protein
DMI73_03210	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMI73_03230	COG0134	indole-3-glycerol-phosphate synthase activity
DMI73_03235	COG0792	nuclease activity
DMI73_03245	COG1253	flavin adenine dinucleotide binding
DMI73_03255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMI73_03270	COG0137	argininosuccinate synthase activity
DMI73_03285	COG0149	triose-phosphate isomerase activity
DMI73_03320	COG1040	competence protein
DMI73_03330	COG3956	TIGRFAM MazG family protein
DMI73_03350	COG1663	tetraacyldisaccharide 4'-kinase activity
DMI73_03360	COG0612	Peptidase, M16
DMI73_03380	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI73_03385	COG0583	DNA-binding transcription factor activity
DMI73_03415	COG0673	inositol 2-dehydrogenase activity
DMI73_03420	COG3034	peptidoglycan biosynthetic process
DMI73_03440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMI73_03445	COG0424	maF-like protein
DMI73_03450	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMI73_03455	COG2815	serine threonine protein kinase
DMI73_03455	COG0515	serine threonine protein kinase
DMI73_03480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMI73_03490	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMI73_03500	COG0571	ribonuclease III activity
DMI73_03520	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMI73_03535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMI73_03555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI73_03570	COG2226	methyltransferase
DMI73_03580	COG2076	Multidrug Resistance protein
DMI73_03810	COG2255	four-way junction helicase activity
DMI73_03815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMI73_03820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI73_03825	COG1215	transferase activity, transferring glycosyl groups
DMI73_03830	COG0463	Glycosyl transferase, family 2
DMI73_03830	COG1216	Glycosyl transferase, family 2
DMI73_03855	COG0438	transferase activity, transferring glycosyl groups
DMI73_03865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI73_03875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMI73_03885	COG0482	sulfurtransferase activity
DMI73_03890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMI73_03900	COG2860	membrane
DMI73_03905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI73_03910	COG2001	Belongs to the MraZ family
DMI73_03915	COG0275	rRNA processing
DMI73_03925	COG0768	penicillin binding
DMI73_03930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMI73_03935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMI73_03940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMI73_03945	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMI73_03955	COG0772	Belongs to the SEDS family
DMI73_03960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMI73_03965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI73_03970	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMI73_03980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMI73_03985	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI73_03990	COG0321	lipoyl(octanoyl) transferase activity
DMI73_03995	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMI73_04000	COG0066	3-isopropylmalate dehydratase activity
DMI73_04010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI73_04025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI73_04035	COG4608	Belongs to the ABC transporter superfamily
DMI73_04040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMI73_04055	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DMI73_04070	COG1137	ATPase activity
DMI73_04080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI73_04105	COG0017	Asparaginyl-tRNA synthetase
DMI73_04115	COG3118	belongs to the thioredoxin family
DMI73_04165	COG0583	DNA-binding transcription factor activity
DMI73_04170	COG2855	membrane
DMI73_04175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMI73_04190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMI73_04200	COG0602	queuosine metabolic process
DMI73_04205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI73_04210	COG0217	transcriptional regulatory protein
DMI73_04215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMI73_04220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI73_04220	COG4651	solute:proton antiporter activity
DMI73_04230	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMI73_04235	COG4864	UPF0365 protein
DMI73_04245	COG2022	thiamine diphosphate biosynthetic process
DMI73_04250	COG0531	amino acid
DMI73_04260	COG0628	permease
DMI73_04265	COG0019	diaminopimelate decarboxylase activity
DMI73_04270	COG0191	fructose-bisphosphate aldolase activity
DMI73_04310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMI73_04340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI73_04345	COG0517	IMP dehydrogenase activity
DMI73_04345	COG0516	GMP reductase activity
DMI73_04350	COG0519	Catalyzes the synthesis of GMP from XMP
DMI73_04350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI73_04360	COG0546	phosphoglycolate phosphatase activity
DMI73_04380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DMI73_04395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMI73_04400	COG0196	riboflavin kinase activity
DMI73_04405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMI73_04420	COG1408	metallophosphoesterase
DMI73_04430	COG1216	Glycosyl transferase, family 2
DMI73_04430	COG1442	glycosyl transferase family 8
DMI73_04440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI73_04445	COG1216	Glycosyl transferase, family 2
DMI73_04465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI73_04465	COG2755	lipolytic protein G-D-S-L family
DMI73_04525	COG0588	phosphoglycerate mutase activity
DMI73_04530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMI73_04540	COG0477	Major facilitator Superfamily
DMI73_04545	COG1607	acyl-coa hydrolase
DMI73_04565	COG1525	nuclease
DMI73_04580	COG1475	DNA binding
DMI73_04585	COG3969	phosphoadenosine phosphosulfate
DMI73_04665	COG3015	lipoprotein NlpE involved in copper resistance
DMI73_04735	COG0305	Participates in initiation and elongation during chromosome replication
DMI73_04835	COG0473	3-isopropylmalate dehydrogenase activity
DMI73_04860	COG2873	o-acetylhomoserine
DMI73_04865	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMI73_04870	COG0535	radical SAM domain protein
DMI73_04885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI73_04890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DMI73_04900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMI73_04910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMI73_04910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMI73_04910	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMI73_04910	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMI73_04920	COG1733	regulation of RNA biosynthetic process
DMI73_04930	COG0107	imidazoleglycerol-phosphate synthase activity
DMI73_04940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI73_04950	COG1643	Atp-dependent helicase
DMI73_04955	COG0440	acetolactate synthase activity
DMI73_04960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI73_04970	COG0445	tRNA wobble uridine modification
DMI73_04980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI73_04980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI73_04985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMI73_04995	COG0592	DNA-directed DNA polymerase activity
DMI73_05020	COG1388	LysM domain
DMI73_05020	COG0791	NLP P60 protein
DMI73_05025	COG0084	hydrolase, TatD family'
DMI73_05035	COG3250	beta-galactosidase activity
DMI73_05050	COG2205	protein histidine kinase activity
DMI73_05055	COG0745	RESPONSE REGULATOR receiver
DMI73_05065	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI73_05075	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI73_05095	COG0542	response to heat
DMI73_05145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMI73_05155	COG0659	secondary active sulfate transmembrane transporter activity
DMI73_05160	COG0165	Argininosuccinate lyase
DMI73_05175	COG0148	phosphopyruvate hydratase activity
DMI73_05180	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMI73_05190	COG3481	metal-dependent phosphohydrolase, HD sub domain
DMI73_05200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI73_05205	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMI73_05255	COG2985	domain, Protein
DMI73_05255	COG0490	domain, Protein
DMI73_05270	COG0471	metal ion transport
DMI73_05310	COG1592	Rubrerythrin
DMI73_05320	COG1363	Peptidase, m42
DMI73_05325	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_05335	COG1785	Belongs to the alkaline phosphatase family
DMI73_05340	COG1970	mechanosensitive ion channel activity
DMI73_05345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMI73_05365	COG2217	Heavy metal translocating P-type atpase
DMI73_05370	COG0497	DNA recombination
DMI73_05375	COG0321	lipoyl(octanoyl) transferase activity
DMI73_05375	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DMI73_05380	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DMI73_05410	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI73_05415	COG0022	dehydrogenase e1 component
DMI73_05420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI73_05430	COG0789	Transcriptional regulator
DMI73_05435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI73_05440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI73_05445	COG3210	domain, Protein
DMI73_05495	COG3409	Peptidoglycan-binding domain 1 protein
DMI73_05495	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI73_05500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMI73_05525	COG1690	Belongs to the RtcB family
DMI73_05535	COG2814	Major facilitator Superfamily
DMI73_05545	COG2096	Adenosyltransferase
DMI73_05555	COG0557	exoribonuclease II activity
DMI73_05565	COG0826	peptidase U32
DMI73_05570	COG0285	dihydrofolate synthase activity
DMI73_05585	COG0673	inositol 2-dehydrogenase activity
DMI73_05590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI73_05595	COG0737	Belongs to the 5'-nucleotidase family
DMI73_05605	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMI73_05610	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMI73_05625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMI73_05630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMI73_05635	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMI73_05640	COG0200	Binds to the 23S rRNA
DMI73_05645	COG0201	protein transport
DMI73_05650	COG0563	adenylate kinase activity
DMI73_05655	COG0024	Methionine aminopeptidase
DMI73_05670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMI73_05675	COG1442	glycosyl transferase family 8
DMI73_05685	COG1216	Glycosyl transferase, family 2
DMI73_05695	COG1216	Glycosyl transferase, family 2
DMI73_05710	COG1216	Glycosyl transferase, family 2
DMI73_05715	COG0693	protein deglycase activity
DMI73_05720	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI73_05725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMI73_05730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI73_05745	COG1966	Carbon starvation protein
DMI73_05765	COG3119	arylsulfatase activity
DMI73_05770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMI73_05775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMI73_05780	COG0195	Participates in both transcription termination and antitermination
DMI73_05785	COG0708	Exodeoxyribonuclease III
DMI73_05790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMI73_05795	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMI73_05800	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMI73_05810	COG1716	ATPase activity
DMI73_05810	COG1131	(ABC) transporter
DMI73_05810	COG0842	Transport permease protein
DMI73_05830	COG0724	RNA recognition motif
DMI73_05835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI73_05855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMI73_05865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMI73_05870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMI73_05885	COG1490	D-aminoacyl-tRNA deacylase activity
DMI73_05900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMI73_05905	COG1053	succinate dehydrogenase
DMI73_05955	COG1028	Short-chain dehydrogenase reductase Sdr
DMI73_05965	COG0488	(ABC) transporter
DMI73_05975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMI73_05985	COG1253	flavin adenine dinucleotide binding
DMI73_05990	COG1028	Short-chain dehydrogenase reductase Sdr
DMI73_06000	COG1073	alpha beta
DMI73_06010	COG0667	Aldo Keto reductase
DMI73_06065	COG2267	carboxylic ester hydrolase activity
DMI73_06070	COG2095	MarC family integral membrane protein
DMI73_06110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI73_06115	COG0488	(ABC) transporter
DMI73_06125	COG0697	spore germination
DMI73_06135	COG0215	cysteine-tRNA ligase activity
DMI73_06145	COG3119	arylsulfatase activity
DMI73_06155	COG0481	GTPase activity
DMI73_06175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMI73_06180	COG0085	RNA polymerase activity
DMI73_06185	COG0222	ribosome binding
DMI73_06190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMI73_06195	COG0081	regulation of translation
DMI73_06200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMI73_06205	COG0250	Participates in transcription elongation, termination and antitermination
DMI73_06220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMI73_06240	COG0740	serine-type endopeptidase activity
DMI73_06245	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMI73_06260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMI73_06280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI73_06325	COG2226	methyltransferase
DMI73_06330	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMI73_06335	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMI73_06355	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMI73_06355	COG1902	pentaerythritol trinitrate reductase activity
DMI73_06365	COG3119	arylsulfatase activity
DMI73_06370	COG0514	ATP-dependent DNA helicase (RecQ)
DMI73_06390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMI73_06395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMI73_06460	COG1858	cytochrome C peroxidase
DMI73_06465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMI73_06470	COG0590	tRNA wobble adenosine to inosine editing
DMI73_06475	COG1940	carbohydrate kinase activity
DMI73_06480	COG2217	Heavy metal translocating P-type atpase
DMI73_06485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI73_06490	COG0237	dephospho-CoA kinase activity
DMI73_06520	COG1363	Peptidase, m42
DMI73_06525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMI73_06535	COG0006	proline dipeptidase activity
DMI73_06540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMI73_06560	COG5002	protein histidine kinase activity
DMI73_06565	COG0745	RESPONSE REGULATOR receiver
DMI73_06570	COG0129	dihydroxy-acid dehydratase activity
DMI73_06595	COG1368	sulfuric ester hydrolase activity
DMI73_06630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMI73_06660	COG0534	Mate efflux family protein
DMI73_06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI73_06680	COG1876	peptidase activity
DMI73_06725	COG3209	COG3209 Rhs family protein
DMI73_06760	COG3209	COG3209 Rhs family protein
DMI73_06810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI73_06815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMI73_06820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI73_06825	COG2205	protein histidine kinase activity
DMI73_06835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI73_06845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI73_06860	COG0667	Aldo Keto reductase
DMI73_06865	COG0789	Transcriptional regulator
DMI73_06915	COG0714	Associated with various cellular activities
DMI73_06920	COG2311	Membrane
DMI73_06945	COG1090	epimerase
DMI73_06960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMI73_06965	COG1119	ATPase activity
DMI73_06970	COG2186	Transcriptional regulator
DMI73_06990	COG0148	phosphopyruvate hydratase activity
DMI73_07000	COG0436	Aminotransferase
DMI73_07005	COG1477	protein flavinylation
DMI73_07020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMI73_07035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMI73_07055	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMI73_07065	COG1199	ATP-dependent helicase activity
DMI73_07070	COG1122	ATPase activity
DMI73_07095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMI73_07100	COG0598	Magnesium transport protein CorA
DMI73_07105	COG0359	binds to the 23S rRNA
DMI73_07110	COG0138	bifunctional purine biosynthesis protein purh
DMI73_07115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMI73_07120	COG0736	holo-[acyl-carrier-protein] synthase activity
DMI73_07130	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMI73_07135	COG3409	Peptidoglycan-binding domain 1 protein
DMI73_07135	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI73_07140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMI73_07150	COG0437	4 iron, 4 sulfur cluster binding
DMI73_07170	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI73_07220	COG0284	orotidine-5'-phosphate decarboxylase activity
DMI73_07240	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMI73_07245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMI73_07265	COG2003	Belongs to the UPF0758 family
DMI73_07270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMI73_07270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMI73_07275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMI73_07280	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMI73_07285	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMI73_07290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMI73_07295	COG0322	excinuclease ABC activity
DMI73_07300	COG0811	peptide transport
DMI73_07305	COG0848	biopolymer transport protein
DMI73_07315	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DMI73_07325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI73_07335	COG1482	cell wall glycoprotein biosynthetic process
DMI73_07345	COG1757	Na H antiporter
DMI73_07350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI73_07355	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMI73_07360	COG0505	Belongs to the CarA family
DMI73_07365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI73_07375	COG0070	glutamate synthase
DMI73_07375	COG0069	glutamate synthase activity
DMI73_07375	COG0067	glutamate synthase
DMI73_07385	COG0706	membrane insertase activity
DMI73_07390	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMI73_07400	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMI73_07420	COG2755	lipolytic protein G-D-S-L family
DMI73_07420	COG0657	acetylesterase activity
DMI73_07430	COG0676	glucose-6-phosphate 1-epimerase activity
DMI73_07435	COG0259	pyridoxamine-phosphate oxidase activity
DMI73_07450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMI73_07465	COG1760	l-serine dehydratase
DMI73_07470	COG3118	belongs to the thioredoxin family
DMI73_07470	COG0492	ferredoxin-NADP+ reductase activity
DMI73_07525	COG1408	metallophosphoesterase
DMI73_07535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMI73_07540	COG0545	Peptidyl-prolyl cis-trans isomerase
DMI73_07560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMI73_07570	COG0826	peptidase U32
DMI73_07580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI73_07610	COG0581	inorganic phosphate transmembrane transporter activity
DMI73_07615	COG0573	inorganic phosphate transmembrane transporter activity
DMI73_07625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMI73_07635	COG2017	converts alpha-aldose to the beta-anomer
DMI73_07650	COG0612	Peptidase, M16
DMI73_07685	COG0233	cytoplasmic translational termination
DMI73_07690	COG0528	UMP kinase activity
DMI73_07695	COG0668	transmembrane transport
DMI73_07700	COG0450	alkyl hydroperoxide reductase
DMI73_07705	COG0733	neurotransmitter:sodium symporter activity
DMI73_07720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMI73_07730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMI73_07735	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMI73_07740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMI73_07765	COG0842	Transport permease protein
DMI73_07770	COG0842	Transport permease protein
DMI73_07775	COG1131	(ABC) transporter
DMI73_07785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMI73_07790	COG1183	phosphatidylcholine synthase activity
DMI73_07800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMI73_07810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMI73_07815	COG1028	Short-chain dehydrogenase reductase Sdr
DMI73_07835	COG0156	8-amino-7-oxononanoate synthase activity
DMI73_07860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMI73_07865	COG0124	histidyl-tRNA synthetase
DMI73_07870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMI73_07875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DMI73_07880	COG0298	carbon dioxide binding
DMI73_07910	COG0443	Heat shock 70 kDa protein
DMI73_07915	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMI73_07920	COG0459	protein refolding
DMI73_07975	COG0632	four-way junction helicase activity
DMI73_07985	COG0126	phosphoglycerate kinase activity
DMI73_08000	COG1082	Xylose isomerase domain protein TIM barrel
DMI73_08005	COG0515	serine threonine protein kinase
DMI73_08005	COG2815	serine threonine protein kinase
DMI73_08010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMI73_08020	COG2271	Major facilitator Superfamily
DMI73_08035	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMI73_08045	COG0037	tRNA processing
DMI73_08050	COG0254	rRNA binding
DMI73_08085	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMI73_08090	COG0039	L-malate dehydrogenase activity
DMI73_08330	COG0778	Nitroreductase
DMI73_08335	COG0564	pseudouridine synthase activity
DMI73_08365	COG1126	abc transporter atp-binding protein
DMI73_08370	COG0765	amino acid transport
DMI73_08380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMI73_08385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMI73_08405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI73_08430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMI73_08435	COG1872	DUF167
DMI73_08440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMI73_08445	COG0484	heat shock protein binding
DMI73_08450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMI73_08460	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI73_08475	COG0277	FAD linked oxidase domain protein
DMI73_08500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMI73_08505	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMI73_08520	COG0131	Imidazoleglycerol-phosphate dehydratase
DMI73_08525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMI73_08530	COG0360	Binds together with S18 to 16S ribosomal RNA
DMI73_08535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMI73_08550	COG1686	Belongs to the peptidase S11 family
DMI73_08555	COG0205	6-phosphofructokinase activity
DMI73_08565	COG0428	transporter
DMI73_08570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI73_08585	COG3977	Valine--pyruvate aminotransferase
DMI73_08590	COG1561	YicC-like family, N-terminal region
DMI73_08600	COG0471	metal ion transport
DMI73_08600	COG3273	potassium ion transport
DMI73_08605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI73_08620	COG1575	Belongs to the MenA family. Type 1 subfamily
DMI73_08660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI73_08660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI73_08680	COG0202	RNA polymerase activity
DMI73_08685	COG0203	ribosomal protein L17
DMI73_08690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMI73_08700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI73_08715	COG2885	chlorophyll binding
DMI73_08785	COG0667	Aldo Keto reductase
DMI73_08790	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMI73_08810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI73_08815	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMI73_08820	COG0134	indole-3-glycerol-phosphate synthase activity
DMI73_08825	COG0135	phosphoribosylanthranilate isomerase activity
DMI73_08835	COG0159	tryptophan synthase activity
DMI73_08855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMI73_08860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMI73_08870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMI73_08900	COG0561	phosphatase activity
DMI73_08905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI73_08910	COG2223	nitrite transmembrane transporter activity
DMI73_08915	COG1205	dead DEAH box helicase
DMI73_08915	COG1111	helicase
DMI73_08920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI73_08955	COG0556	nucleotide-excision repair
DMI73_08965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMI73_08970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMI73_08975	COG0750	zinc metalloprotease
DMI73_08990	COG1074	ATP-dependent DNA helicase activity
DMI73_09000	COG0697	spore germination
DMI73_09010	COG1002	Type II restriction enzyme, methylase subunits
DMI73_09015	COG1061	Type III restriction enzyme res subunit
DMI73_09020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMI73_09025	COG2373	Large extracellular alpha-helical protein
DMI73_09030	COG1979	alcohol dehydrogenase
DMI73_09040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMI73_09065	COG0372	Belongs to the citrate synthase family
DMI73_09080	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMI73_09090	COG1187	pseudouridine synthase activity
DMI73_09100	COG0105	UTP biosynthetic process
DMI73_09105	COG1215	transferase activity, transferring glycosyl groups
DMI73_09110	COG0463	Glycosyl transferase, family 2
DMI73_09120	COG1459	type II secretion system
DMI73_09125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI73_09135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI73_09150	COG0728	peptidoglycan biosynthetic process
DMI73_09155	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMI73_09155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI73_09165	COG1649	PFAM Uncharacterised BCR, COG1649
DMI73_09170	COG1691	(AIR) carboxylase
DMI73_09175	COG0037	tRNA processing
DMI73_09180	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMI73_09185	COG0142	geranyltranstransferase activity
DMI73_09200	COG2151	metal-sulfur cluster biosynthetic enzyme
DMI73_09215	COG1007	ATP synthesis coupled electron transport
DMI73_09220	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI73_09230	COG0713	ATP synthesis coupled electron transport
DMI73_09235	COG0839	Belongs to the complex I subunit 6 family
DMI73_09245	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMI73_09250	COG1034	ATP synthesis coupled electron transport
DMI73_09255	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI73_09260	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DMI73_09275	COG0726	polysaccharide deacetylase
DMI73_09285	COG0307	riboflavin synthase, alpha
DMI73_09295	COG2264	protein methyltransferase activity
DMI73_09305	COG3210	domain, Protein
DMI73_09310	COG1640	4-alpha-glucanotransferase
DMI73_09325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI73_09330	COG1030	water channel activity
DMI73_09335	COG0358	DNA primase activity
DMI73_09340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMI73_09345	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMI73_09360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMI73_09365	COG0793	Belongs to the peptidase S41A family
DMI73_09380	COG1643	Atp-dependent helicase
DMI73_09405	COG1450	Type ii and iii secretion system protein
DMI73_09420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMI73_09440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI73_09445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMI73_09455	COG0268	Binds directly to 16S ribosomal RNA
DMI73_09460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI73_09465	COG0028	Belongs to the TPP enzyme family
DMI73_09475	COG0688	phosphatidylethanolamine metabolic process
DMI73_09480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMI73_09485	COG0495	leucyl-tRNA aminoacylation
DMI73_09490	COG3119	arylsulfatase activity
DMI73_09505	COG1166	arginine decarboxylase activity
DMI73_09515	COG3250	beta-galactosidase activity
DMI73_09520	COG3250	beta-galactosidase activity
DMI73_09525	COG3250	beta-galactosidase activity
DMI73_09530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DMI73_09535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_09550	COG0205	6-phosphofructokinase activity
DMI73_09585	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMI73_09590	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMI73_09595	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMI73_09610	COG4771	TonB-dependent receptor
DMI73_09630	COG0402	S-adenosylhomocysteine deaminase activity
DMI73_09635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMI73_09655	COG1196	nuclear chromosome segregation
DMI73_09690	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI73_09700	COG1294	oxidase, subunit
DMI73_09705	COG1271	oxidase subunit
DMI73_09715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI73_09740	COG1846	Transcriptional regulator
DMI73_09765	COG2949	membrane
DMI73_09795	COG0514	ATP-dependent DNA helicase (RecQ)
DMI73_09810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMI73_09815	COG0045	succinate-CoA ligase (ADP-forming) activity
DMI73_09820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMI73_09890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI73_09895	COG2205	protein histidine kinase activity
DMI73_09910	COG0113	porphobilinogen synthase activity
DMI73_09925	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMI73_09930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMI73_09945	COG0732	type I restriction modification DNA specificity domain
DMI73_09960	COG0732	type I restriction modification DNA specificity domain
DMI73_09970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMI73_09995	COG4106	trans-aconitate 2-methyltransferase activity
DMI73_10010	COG3475	LICD family
DMI73_10015	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI73_10025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI73_10030	COG3475	LICD family
DMI73_10035	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMI73_10045	COG2166	iron-sulfur cluster assembly
DMI73_10050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMI73_10060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI73_10065	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMI73_10070	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMI73_10075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMI73_10080	COG1131	(ABC) transporter
DMI73_10110	COG1215	transferase activity, transferring glycosyl groups
DMI73_10120	COG2967	ApaG domain
DMI73_10130	COG1522	sequence-specific DNA binding
DMI73_10135	COG0436	Aminotransferase
DMI73_10150	COG0423	glycine-tRNA ligase activity
DMI73_10155	COG0656	L-ascorbic acid biosynthetic process
DMI73_10175	COG2304	oxidoreductase activity
DMI73_10195	COG0714	Associated with various cellular activities
DMI73_10200	COG0154	amidase activity
DMI73_10205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI73_10245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI73_10250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI73_10260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI73_10260	COG2755	lipolytic protein G-D-S-L family
DMI73_10295	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI73_10305	COG0656	L-ascorbic acid biosynthetic process
DMI73_10315	COG0667	Aldo Keto reductase
DMI73_10320	COG1408	metallophosphoesterase
DMI73_10340	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMI73_10345	COG0789	Transcriptional regulator
DMI73_10360	COG0534	Mate efflux family protein
DMI73_10380	COG1091	dTDP-4-dehydrorhamnose reductase activity
DMI73_10395	COG1837	Belongs to the UPF0109 family
DMI73_10405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI73_10410	COG0363	glucosamine-6-phosphate deaminase activity
DMI73_10425	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DMI73_10435	COG1741	Belongs to the pirin family
DMI73_10455	COG1070	Carbohydrate kinase
DMI73_10470	COG0738	Major facilitator superfamily
DMI73_10485	COG1595	DNA-templated transcription, initiation
DMI73_10505	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMI73_10525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI73_10535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMI73_10540	COG2132	Multicopper oxidase
DMI73_10545	COG0697	spore germination
DMI73_10550	COG3586	endonuclease activity
DMI73_10565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI73_10570	COG4608	Belongs to the ABC transporter superfamily
DMI73_10575	COG0444	Belongs to the ABC transporter superfamily
DMI73_10580	COG4166	transmembrane transport
DMI73_10585	COG4239	(ABC) transporter, permease
DMI73_10590	COG0601	transmembrane transport
DMI73_10610	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMI73_10615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DMI73_10620	COG3738	Protein conserved in bacteria
DMI73_10625	COG0151	Belongs to the GarS family
DMI73_10640	COG0811	peptide transport
DMI73_10650	COG0242	peptide deformylase activity
DMI73_10685	COG2010	Cytochrome c
DMI73_10695	COG3258	Cytochrome c
DMI73_10710	COG3274	enterobacterial common antigen metabolic process
DMI73_10715	COG0538	isocitrate dehydrogenase activity
DMI73_10735	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI73_10740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMI73_10745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMI73_10755	COG0668	transmembrane transport
DMI73_10760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI73_10760	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMI73_10765	COG0805	protein transport
DMI73_10770	COG1968	undecaprenyl-diphosphatase activity
DMI73_10790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMI73_10800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMI73_10810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMI73_10820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI73_10830	COG1408	metallophosphoesterase
DMI73_10855	COG4974	Belongs to the 'phage' integrase family
DMI73_10875	COG1454	alcohol dehydrogenase
DMI73_10880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMI73_10890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DMI73_10890	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DMI73_10895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMI73_10945	COG4607	ABC-type enterochelin transport system periplasmic component
DMI73_10950	COG4604	ABC transporter, ATP-binding protein
DMI73_10955	COG4605	iron ion homeostasis
DMI73_10960	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMI73_10995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI73_10995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI73_11010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMI73_11020	COG2195	Cleaves the N-terminal amino acid of tripeptides
DMI73_11040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI73_11060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI73_11085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI73_11085	COG0519	Catalyzes the synthesis of GMP from XMP
DMI73_11090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMI73_11135	COG2966	Psort location CytoplasmicMembrane, score
DMI73_11140	COG3610	response to peptide
DMI73_11150	COG0460	homoserine dehydrogenase
DMI73_11155	COG0527	aspartate kinase activity
DMI73_11165	COG5522	Integral membrane protein (intg_mem_TP0381)
DMI73_11180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMI73_11190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMI73_11195	COG1194	a g-specific adenine glycosylase
DMI73_11200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMI73_11205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI73_11205	COG0574	Belongs to the PEP-utilizing enzyme family
DMI73_11215	COG0166	Belongs to the GPI family
DMI73_11225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI73_11245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI73_11245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI73_11280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMI73_11285	COG2818	Glycosylase
DMI73_11305	COG3033	Beta-eliminating lyase
DMI73_11320	COG0072	phenylalanine-tRNA ligase activity
DMI73_11320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI73_11335	COG3059	membrane
DMI73_11345	COG0326	Molecular chaperone. Has ATPase activity
DMI73_11370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI73_11375	COG1959	2 iron, 2 sulfur cluster binding
DMI73_11390	COG0352	thiamine-phosphate diphosphorylase activity
DMI73_11395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMI73_11410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_11420	COG1703	isobutyryl-CoA mutase activity
DMI73_11440	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMI73_11450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI73_11455	COG0418	dihydroorotase activity
DMI73_11470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI73_11490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMI73_11520	COG0534	Mate efflux family protein
DMI73_11525	COG0489	protein tyrosine kinase activity
DMI73_11540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI73_11550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI73_11560	COG1538	Outer membrane efflux protein
DMI73_11580	COG4112	unkown
DMI73_11600	COG0038	chloride channel
DMI73_11625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMI73_11635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI73_11640	COG0586	Pfam SNARE associated Golgi protein
DMI73_11710	COG1012	belongs to the aldehyde dehydrogenase family
DMI73_11730	COG0753	catalase activity
DMI73_11740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI73_11745	COG1592	Rubrerythrin
DMI73_11750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMI73_11770	COG0489	protein tyrosine kinase activity
DMI73_11780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI73_11790	COG2244	polysaccharide biosynthetic process
DMI73_11795	COG1216	Glycosyl transferase, family 2
DMI73_11805	COG1216	Glycosyl transferase, family 2
DMI73_11815	COG0438	transferase activity, transferring glycosyl groups
DMI73_11820	COG0438	transferase activity, transferring glycosyl groups
DMI73_11850	COG1216	Glycosyl transferase, family 2
DMI73_11895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI73_11900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI73_11905	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DMI73_11920	COG0281	malic enzyme
DMI73_11920	COG0280	phosphate acetyltransferase
DMI73_11935	COG1472	Belongs to the glycosyl hydrolase 3 family
DMI73_11940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMI73_11955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMI73_11965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMI73_11970	COG1063	alcohol dehydrogenase
DMI73_11985	COG0714	Associated with various cellular activities
DMI73_11995	COG0193	aminoacyl-tRNA hydrolase activity
DMI73_12000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMI73_12015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMI73_12040	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DMI73_12055	COG0375	protein maturation
DMI73_12080	COG0778	Nitroreductase
DMI73_12085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI73_12105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI73_12105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI73_12120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI73_12120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI73_12140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI73_12145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMI73_12150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMI73_12195	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI73_12200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI73_12215	COG0318	PFAM AMP-dependent synthetase and ligase
DMI73_12250	COG0339	signal peptide processing
DMI73_12260	COG0018	arginyl-trna synthetase
DMI73_12295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI73_12300	COG0653	protein targeting
DMI73_12315	COG0494	nUDIX hydrolase