locus-tag	class	description
DMI74_00045	COG0534	Mate efflux family protein
DMI74_00050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI74_00065	COG1876	peptidase activity
DMI74_00110	COG3209	COG3209 Rhs family protein
DMI74_00145	COG3209	COG3209 Rhs family protein
DMI74_00195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI74_00200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMI74_00205	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI74_00210	COG2205	protein histidine kinase activity
DMI74_00220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI74_00230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI74_00245	COG0667	Aldo Keto reductase
DMI74_00250	COG0789	Transcriptional regulator
DMI74_00300	COG0714	Associated with various cellular activities
DMI74_00305	COG2311	Membrane
DMI74_00330	COG1090	epimerase
DMI74_00345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMI74_00350	COG1119	ATPase activity
DMI74_00355	COG2186	Transcriptional regulator
DMI74_00375	COG0148	phosphopyruvate hydratase activity
DMI74_00385	COG0436	Aminotransferase
DMI74_00390	COG1477	protein flavinylation
DMI74_00405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMI74_00420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMI74_00440	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMI74_00450	COG1199	ATP-dependent helicase activity
DMI74_00455	COG1122	ATPase activity
DMI74_00480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMI74_00485	COG0598	Magnesium transport protein CorA
DMI74_00490	COG0359	binds to the 23S rRNA
DMI74_00495	COG0138	bifunctional purine biosynthesis protein purh
DMI74_00500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMI74_00505	COG0736	holo-[acyl-carrier-protein] synthase activity
DMI74_00515	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMI74_00520	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI74_00520	COG3409	Peptidoglycan-binding domain 1 protein
DMI74_00525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMI74_00535	COG0437	4 iron, 4 sulfur cluster binding
DMI74_00555	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI74_00605	COG0284	orotidine-5'-phosphate decarboxylase activity
DMI74_00625	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMI74_00630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMI74_00650	COG2003	Belongs to the UPF0758 family
DMI74_00655	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMI74_00655	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMI74_00660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMI74_00665	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMI74_00670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMI74_00675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMI74_00680	COG0322	excinuclease ABC activity
DMI74_00685	COG0811	peptide transport
DMI74_00690	COG0848	biopolymer transport protein
DMI74_00700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DMI74_00710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI74_00720	COG1482	cell wall glycoprotein biosynthetic process
DMI74_00730	COG1757	Na H antiporter
DMI74_00735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI74_00740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMI74_00745	COG0505	Belongs to the CarA family
DMI74_00750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI74_00760	COG0067	glutamate synthase
DMI74_00760	COG0069	glutamate synthase activity
DMI74_00760	COG0070	glutamate synthase
DMI74_00770	COG0706	membrane insertase activity
DMI74_00775	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMI74_00785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMI74_00800	COG2755	lipolytic protein G-D-S-L family
DMI74_00800	COG0657	acetylesterase activity
DMI74_00810	COG0676	glucose-6-phosphate 1-epimerase activity
DMI74_00815	COG0259	pyridoxamine-phosphate oxidase activity
DMI74_00830	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMI74_00850	COG1760	l-serine dehydratase
DMI74_00855	COG3118	belongs to the thioredoxin family
DMI74_00855	COG0492	ferredoxin-NADP+ reductase activity
DMI74_00910	COG1408	metallophosphoesterase
DMI74_00920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMI74_00925	COG0545	Peptidyl-prolyl cis-trans isomerase
DMI74_00945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMI74_00955	COG0826	peptidase U32
DMI74_00965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI74_00995	COG0581	inorganic phosphate transmembrane transporter activity
DMI74_01000	COG0573	inorganic phosphate transmembrane transporter activity
DMI74_01010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMI74_01020	COG2017	converts alpha-aldose to the beta-anomer
DMI74_01035	COG0612	Peptidase, M16
DMI74_01070	COG0233	cytoplasmic translational termination
DMI74_01075	COG0528	UMP kinase activity
DMI74_01080	COG0668	transmembrane transport
DMI74_01085	COG0450	alkyl hydroperoxide reductase
DMI74_01090	COG0733	neurotransmitter:sodium symporter activity
DMI74_01105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMI74_01115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMI74_01120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMI74_01125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMI74_01150	COG0842	Transport permease protein
DMI74_01155	COG0842	Transport permease protein
DMI74_01160	COG1131	(ABC) transporter
DMI74_01170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMI74_01175	COG1183	phosphatidylcholine synthase activity
DMI74_01185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMI74_01195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMI74_01200	COG1028	Short-chain dehydrogenase reductase Sdr
DMI74_01225	COG0156	8-amino-7-oxononanoate synthase activity
DMI74_01250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMI74_01255	COG0124	histidyl-tRNA synthetase
DMI74_01260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMI74_01265	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DMI74_01270	COG0298	carbon dioxide binding
DMI74_01300	COG0443	Heat shock 70 kDa protein
DMI74_01305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMI74_01310	COG0459	protein refolding
DMI74_01360	COG0632	four-way junction helicase activity
DMI74_01370	COG0126	phosphoglycerate kinase activity
DMI74_01385	COG1082	Xylose isomerase domain protein TIM barrel
DMI74_01390	COG0515	serine threonine protein kinase
DMI74_01390	COG2815	serine threonine protein kinase
DMI74_01395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMI74_01405	COG2271	Major facilitator Superfamily
DMI74_01420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMI74_01430	COG0037	tRNA processing
DMI74_01435	COG0254	rRNA binding
DMI74_01470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMI74_01475	COG0039	L-malate dehydrogenase activity
DMI74_01715	COG0778	Nitroreductase
DMI74_01720	COG0564	pseudouridine synthase activity
DMI74_01750	COG1126	abc transporter atp-binding protein
DMI74_01755	COG0765	amino acid transport
DMI74_01765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMI74_01770	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMI74_01790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI74_01815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMI74_01820	COG1872	DUF167
DMI74_01825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMI74_01830	COG0484	heat shock protein binding
DMI74_01835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMI74_01845	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI74_01860	COG0277	FAD linked oxidase domain protein
DMI74_01885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMI74_01890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMI74_01905	COG0131	Imidazoleglycerol-phosphate dehydratase
DMI74_01910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMI74_01915	COG0360	Binds together with S18 to 16S ribosomal RNA
DMI74_01920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMI74_01935	COG1686	Belongs to the peptidase S11 family
DMI74_01940	COG0205	6-phosphofructokinase activity
DMI74_01950	COG0428	transporter
DMI74_01955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI74_01970	COG3977	Valine--pyruvate aminotransferase
DMI74_01975	COG1561	YicC-like family, N-terminal region
DMI74_01985	COG0471	metal ion transport
DMI74_01985	COG3273	potassium ion transport
DMI74_01990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI74_02005	COG1575	Belongs to the MenA family. Type 1 subfamily
DMI74_02045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI74_02045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI74_02065	COG0202	RNA polymerase activity
DMI74_02070	COG0203	ribosomal protein L17
DMI74_02075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMI74_02085	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI74_02100	COG2885	chlorophyll binding
DMI74_02170	COG0667	Aldo Keto reductase
DMI74_02175	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMI74_02195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI74_02200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMI74_02205	COG0134	indole-3-glycerol-phosphate synthase activity
DMI74_02210	COG0135	phosphoribosylanthranilate isomerase activity
DMI74_02220	COG0159	tryptophan synthase activity
DMI74_02240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMI74_02245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMI74_02255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMI74_02285	COG0561	phosphatase activity
DMI74_02290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI74_02295	COG2223	nitrite transmembrane transporter activity
DMI74_02300	COG1111	helicase
DMI74_02300	COG1205	dead DEAH box helicase
DMI74_02305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI74_02340	COG0556	nucleotide-excision repair
DMI74_02350	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMI74_02355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMI74_02360	COG0750	zinc metalloprotease
DMI74_02375	COG1074	ATP-dependent DNA helicase activity
DMI74_02385	COG0697	spore germination
DMI74_02395	COG1002	Type II restriction enzyme, methylase subunits
DMI74_02400	COG1061	Type III restriction enzyme res subunit
DMI74_02405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMI74_02410	COG2373	Large extracellular alpha-helical protein
DMI74_02415	COG1979	alcohol dehydrogenase
DMI74_02425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMI74_02450	COG0372	Belongs to the citrate synthase family
DMI74_02465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMI74_02475	COG1187	pseudouridine synthase activity
DMI74_02485	COG0105	UTP biosynthetic process
DMI74_02490	COG1215	transferase activity, transferring glycosyl groups
DMI74_02495	COG0463	Glycosyl transferase, family 2
DMI74_02505	COG1459	type II secretion system
DMI74_02510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI74_02520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI74_02535	COG0728	peptidoglycan biosynthetic process
DMI74_02540	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMI74_02540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI74_02550	COG1649	PFAM Uncharacterised BCR, COG1649
DMI74_02555	COG1691	(AIR) carboxylase
DMI74_02560	COG0037	tRNA processing
DMI74_02565	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMI74_02570	COG0142	geranyltranstransferase activity
DMI74_02585	COG2151	metal-sulfur cluster biosynthetic enzyme
DMI74_02600	COG1007	ATP synthesis coupled electron transport
DMI74_02605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI74_02615	COG0713	ATP synthesis coupled electron transport
DMI74_02620	COG0839	Belongs to the complex I subunit 6 family
DMI74_02630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMI74_02635	COG1034	ATP synthesis coupled electron transport
DMI74_02640	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI74_02645	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DMI74_02650	COG0649	NAD binding
DMI74_02660	COG0726	polysaccharide deacetylase
DMI74_02670	COG0307	riboflavin synthase, alpha
DMI74_02680	COG2264	protein methyltransferase activity
DMI74_02685	COG3210	domain, Protein
DMI74_02690	COG1640	4-alpha-glucanotransferase
DMI74_02705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI74_02710	COG1030	water channel activity
DMI74_02715	COG0358	DNA primase activity
DMI74_02720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMI74_02725	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMI74_02740	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMI74_02745	COG0793	Belongs to the peptidase S41A family
DMI74_02760	COG1643	Atp-dependent helicase
DMI74_02785	COG1450	Type ii and iii secretion system protein
DMI74_02800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMI74_02820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI74_02825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMI74_02835	COG0268	Binds directly to 16S ribosomal RNA
DMI74_02840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI74_02845	COG0028	Belongs to the TPP enzyme family
DMI74_02855	COG0688	phosphatidylethanolamine metabolic process
DMI74_02860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMI74_02865	COG0495	leucyl-tRNA aminoacylation
DMI74_02870	COG3119	arylsulfatase activity
DMI74_02885	COG1166	arginine decarboxylase activity
DMI74_02895	COG3250	beta-galactosidase activity
DMI74_02900	COG3250	beta-galactosidase activity
DMI74_02905	COG3250	beta-galactosidase activity
DMI74_02910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DMI74_02915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_02930	COG0205	6-phosphofructokinase activity
DMI74_02965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMI74_02970	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMI74_02975	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMI74_02990	COG4771	TonB-dependent receptor
DMI74_03010	COG0402	S-adenosylhomocysteine deaminase activity
DMI74_03015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMI74_03035	COG1196	nuclear chromosome segregation
DMI74_03070	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI74_03080	COG1294	oxidase, subunit
DMI74_03085	COG1271	oxidase subunit
DMI74_03095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI74_03115	COG1846	Transcriptional regulator
DMI74_03140	COG2949	membrane
DMI74_03170	COG0514	ATP-dependent DNA helicase (RecQ)
DMI74_03185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMI74_03190	COG0045	succinate-CoA ligase (ADP-forming) activity
DMI74_03195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMI74_03265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI74_03270	COG2205	protein histidine kinase activity
DMI74_03285	COG0113	porphobilinogen synthase activity
DMI74_03300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMI74_03305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DMI74_03320	COG0732	type I restriction modification DNA specificity domain
DMI74_03335	COG0732	type I restriction modification DNA specificity domain
DMI74_03345	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMI74_03370	COG4106	trans-aconitate 2-methyltransferase activity
DMI74_03385	COG3475	LICD family
DMI74_03390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI74_03400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI74_03405	COG3475	LICD family
DMI74_03410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMI74_03420	COG2166	iron-sulfur cluster assembly
DMI74_03425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMI74_03435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI74_03440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMI74_03445	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMI74_03450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMI74_03455	COG1131	(ABC) transporter
DMI74_03470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DMI74_03485	COG1215	transferase activity, transferring glycosyl groups
DMI74_03495	COG2967	ApaG domain
DMI74_03505	COG1522	sequence-specific DNA binding
DMI74_03510	COG0436	Aminotransferase
DMI74_03525	COG0423	glycine-tRNA ligase activity
DMI74_03530	COG0656	L-ascorbic acid biosynthetic process
DMI74_03560	COG2304	oxidoreductase activity
DMI74_03575	COG0714	Associated with various cellular activities
DMI74_03580	COG0154	amidase activity
DMI74_03585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI74_03625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI74_03630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI74_03640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI74_03640	COG2755	lipolytic protein G-D-S-L family
DMI74_03675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI74_03685	COG0656	L-ascorbic acid biosynthetic process
DMI74_03695	COG0667	Aldo Keto reductase
DMI74_03700	COG1408	metallophosphoesterase
DMI74_03720	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMI74_03725	COG0789	Transcriptional regulator
DMI74_03740	COG0534	Mate efflux family protein
DMI74_03765	COG1091	dTDP-4-dehydrorhamnose reductase activity
DMI74_03780	COG1837	Belongs to the UPF0109 family
DMI74_03790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI74_03795	COG0363	glucosamine-6-phosphate deaminase activity
DMI74_03810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DMI74_03820	COG1741	Belongs to the pirin family
DMI74_03840	COG1070	Carbohydrate kinase
DMI74_03855	COG0738	Major facilitator superfamily
DMI74_03870	COG1595	DNA-templated transcription, initiation
DMI74_03890	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMI74_03910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI74_03920	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMI74_03925	COG2132	Multicopper oxidase
DMI74_03930	COG0697	spore germination
DMI74_03935	COG3586	endonuclease activity
DMI74_03950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI74_03955	COG4608	Belongs to the ABC transporter superfamily
DMI74_03960	COG0444	Belongs to the ABC transporter superfamily
DMI74_03965	COG4166	transmembrane transport
DMI74_03970	COG4239	(ABC) transporter, permease
DMI74_03975	COG0601	transmembrane transport
DMI74_03995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMI74_04000	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DMI74_04005	COG3738	Protein conserved in bacteria
DMI74_04010	COG0151	Belongs to the GarS family
DMI74_04025	COG0811	peptide transport
DMI74_04035	COG0242	peptide deformylase activity
DMI74_04070	COG2010	Cytochrome c
DMI74_04080	COG3258	Cytochrome c
DMI74_04095	COG3274	enterobacterial common antigen metabolic process
DMI74_04100	COG0538	isocitrate dehydrogenase activity
DMI74_04120	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI74_04125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMI74_04130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMI74_04140	COG0668	transmembrane transport
DMI74_04145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI74_04145	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMI74_04150	COG0805	protein transport
DMI74_04155	COG1968	undecaprenyl-diphosphatase activity
DMI74_04175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMI74_04185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMI74_04195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMI74_04210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI74_04220	COG1408	metallophosphoesterase
DMI74_04245	COG4974	Belongs to the 'phage' integrase family
DMI74_04265	COG1454	alcohol dehydrogenase
DMI74_04270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMI74_04280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DMI74_04280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DMI74_04285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMI74_04325	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI74_04335	COG4607	ABC-type enterochelin transport system periplasmic component
DMI74_04340	COG4604	ABC transporter, ATP-binding protein
DMI74_04345	COG4605	iron ion homeostasis
DMI74_04350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMI74_04385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI74_04385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI74_04400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMI74_04410	COG2195	Cleaves the N-terminal amino acid of tripeptides
DMI74_04430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI74_04450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI74_04475	COG0519	Catalyzes the synthesis of GMP from XMP
DMI74_04475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI74_04480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMI74_04520	COG0646	methionine synthase
DMI74_04520	COG1410	methionine synthase
DMI74_04525	COG2966	Psort location CytoplasmicMembrane, score
DMI74_04530	COG3610	response to peptide
DMI74_04540	COG0460	homoserine dehydrogenase
DMI74_04545	COG0527	aspartate kinase activity
DMI74_04555	COG5522	Integral membrane protein (intg_mem_TP0381)
DMI74_04570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMI74_04580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMI74_04585	COG1194	a g-specific adenine glycosylase
DMI74_04590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMI74_04595	COG0574	Belongs to the PEP-utilizing enzyme family
DMI74_04595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI74_04605	COG0166	Belongs to the GPI family
DMI74_04615	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI74_04635	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI74_04635	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI74_04670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMI74_04675	COG2818	Glycosylase
DMI74_04695	COG3033	Beta-eliminating lyase
DMI74_04710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI74_04710	COG0072	phenylalanine-tRNA ligase activity
DMI74_04725	COG3059	membrane
DMI74_04735	COG0326	Molecular chaperone. Has ATPase activity
DMI74_04760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI74_04765	COG1959	2 iron, 2 sulfur cluster binding
DMI74_04780	COG0352	thiamine-phosphate diphosphorylase activity
DMI74_04785	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMI74_04800	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_04810	COG1703	isobutyryl-CoA mutase activity
DMI74_04830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMI74_04840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI74_04845	COG0418	dihydroorotase activity
DMI74_04860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI74_04880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMI74_04910	COG0534	Mate efflux family protein
DMI74_04915	COG0489	protein tyrosine kinase activity
DMI74_04930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI74_04940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI74_04950	COG1538	Outer membrane efflux protein
DMI74_04970	COG4112	unkown
DMI74_04990	COG0038	chloride channel
DMI74_05015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMI74_05025	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI74_05030	COG0586	Pfam SNARE associated Golgi protein
DMI74_05100	COG1012	belongs to the aldehyde dehydrogenase family
DMI74_05120	COG0753	catalase activity
DMI74_05130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI74_05135	COG1592	Rubrerythrin
DMI74_05140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMI74_05160	COG0489	protein tyrosine kinase activity
DMI74_05170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI74_05180	COG2244	polysaccharide biosynthetic process
DMI74_05185	COG1216	Glycosyl transferase, family 2
DMI74_05195	COG1216	Glycosyl transferase, family 2
DMI74_05205	COG0438	transferase activity, transferring glycosyl groups
DMI74_05210	COG0438	transferase activity, transferring glycosyl groups
DMI74_05240	COG1216	Glycosyl transferase, family 2
DMI74_05285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI74_05295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI74_05300	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DMI74_05315	COG0281	malic enzyme
DMI74_05315	COG0280	phosphate acetyltransferase
DMI74_05330	COG1472	Belongs to the glycosyl hydrolase 3 family
DMI74_05335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMI74_05350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMI74_05360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMI74_05365	COG1063	alcohol dehydrogenase
DMI74_05380	COG0714	Associated with various cellular activities
DMI74_05390	COG0193	aminoacyl-tRNA hydrolase activity
DMI74_05395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMI74_05410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMI74_05435	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DMI74_05450	COG0375	protein maturation
DMI74_05475	COG0778	Nitroreductase
DMI74_05480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI74_05500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI74_05500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI74_05515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI74_05515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI74_05535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_05540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMI74_05545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMI74_05590	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI74_05595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI74_05610	COG0318	PFAM AMP-dependent synthetase and ligase
DMI74_05640	COG0339	signal peptide processing
DMI74_05650	COG0018	arginyl-trna synthetase
DMI74_05685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI74_05690	COG0653	protein targeting
DMI74_05705	COG0494	nUDIX hydrolase
DMI74_05710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMI74_05715	COG1131	(ABC) transporter
DMI74_05735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMI74_05740	COG0564	pseudouridine synthase activity
DMI74_05755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMI74_05760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMI74_05770	COG0513	Belongs to the DEAD box helicase family
DMI74_05780	COG0673	inositol 2-dehydrogenase activity
DMI74_05800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DMI74_05820	COG1971	Probably functions as a manganese efflux pump
DMI74_05850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI74_05875	COG0442	prolyl-tRNA aminoacylation
DMI74_05905	COG0531	amino acid
DMI74_05910	COG2066	Belongs to the glutaminase family
DMI74_05920	COG1115	amino acid carrier protein
DMI74_05930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMI74_05935	COG2890	protein-(glutamine-N5) methyltransferase activity
DMI74_05940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMI74_05945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMI74_05965	COG2226	methyltransferase
DMI74_05970	COG0534	Mate efflux family protein
DMI74_06040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI74_06045	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DMI74_06050	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_06070	COG1121	(ABC) transporter
DMI74_06075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMI74_06080	COG3880	PFAM UvrB UvrC protein
DMI74_06085	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DMI74_06090	COG0542	response to heat
DMI74_06105	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMI74_06110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI74_06125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI74_06125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMI74_06140	COG0180	Tryptophanyl-tRNA synthetase
DMI74_06150	COG1692	metallophosphoesterase
DMI74_06160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DMI74_06175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMI74_06180	COG2816	NAD+ diphosphatase activity
DMI74_06190	COG0156	8-amino-7-oxononanoate synthase activity
DMI74_06205	COG0515	serine threonine protein kinase
DMI74_06205	COG3266	domain, Protein
DMI74_06395	COG1598	PFAM Uncharacterised protein family UPF0150
DMI74_06475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMI74_06495	COG0732	type I restriction modification DNA specificity domain
DMI74_06500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DMI74_06505	COG3189	MarR family transcriptional regulator
DMI74_06515	COG0181	hydroxymethylbilane synthase activity
DMI74_06520	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMI74_06530	COG1469	GTP cyclohydrolase I activity
DMI74_06535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMI74_06540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMI74_06545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMI74_06550	COG1940	carbohydrate kinase activity
DMI74_06565	COG0494	nUDIX hydrolase
DMI74_06570	COG1566	PFAM secretion protein HlyD family protein
DMI74_06575	COG0577	efflux transmembrane transporter activity
DMI74_06575	COG1136	(ABC) transporter
DMI74_06580	COG0577	efflux transmembrane transporter activity
DMI74_06580	COG1136	(ABC) transporter
DMI74_06585	COG1538	Outer membrane efflux protein
DMI74_06600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI74_06615	COG1720	tRNA m6t6A37 methyltransferase activity
DMI74_06620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMI74_06625	COG0540	Belongs to the ATCase OTCase family
DMI74_06630	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMI74_06645	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DMI74_06650	COG2957	Belongs to the agmatine deiminase family
DMI74_06660	COG0750	zinc metalloprotease
DMI74_06670	COG3119	arylsulfatase activity
DMI74_06680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI74_06680	COG1918	ferrous iron import across plasma membrane
DMI74_06745	COG1475	DNA binding
DMI74_06780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMI74_06795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMI74_06800	COG0601	transmembrane transport
DMI74_06865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMI74_06870	COG1132	(ABC) transporter
DMI74_06875	COG1132	(ABC) transporter
DMI74_06890	COG1127	ABC transporter
DMI74_06895	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMI74_06925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMI74_06940	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DMI74_06945	COG0504	CTP synthase activity
DMI74_06950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMI74_06975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI74_06985	COG1322	Protein conserved in bacteria
DMI74_06990	COG0546	phosphoglycolate phosphatase activity
DMI74_06995	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI74_07005	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI74_07030	COG2755	lipolytic protein G-D-S-L family
DMI74_07030	COG0657	acetylesterase activity
DMI74_07035	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMI74_07055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMI74_07075	COG0335	large ribosomal subunit rRNA binding
DMI74_07085	COG0346	lactoylglutathione lyase activity
DMI74_07100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMI74_07105	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DMI74_07110	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DMI74_07110	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DMI74_07115	COG0427	acetyl-CoA hydrolase
DMI74_07125	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMI74_07135	COG0205	6-phosphofructokinase activity
DMI74_07145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI74_07150	COG0028	Belongs to the TPP enzyme family
DMI74_07170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMI74_07185	COG0471	metal ion transport
DMI74_07195	COG0351	phosphomethylpyrimidine kinase
DMI74_07260	COG0242	peptide deformylase activity
DMI74_07265	COG1063	alcohol dehydrogenase
DMI74_07275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMI74_07280	COG1393	Belongs to the ArsC family
DMI74_07285	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI74_07295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMI74_07305	COG1187	pseudouridine synthase activity
DMI74_07315	COG0336	Belongs to the RNA methyltransferase TrmD family
DMI74_07320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMI74_07330	COG0539	negative regulation of cytoplasmic translation
DMI74_07375	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMI74_07380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMI74_07385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMI74_07390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI74_07430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI74_07455	COG0662	Cupin 2, conserved barrel domain protein
DMI74_07455	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMI74_07465	COG0416	fatty acid biosynthetic process
DMI74_07470	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMI74_07480	COG0537	adenosine 5'-monophosphoramidase activity
DMI74_07485	COG0009	L-threonylcarbamoyladenylate synthase
DMI74_07490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMI74_07495	COG0228	four-way junction DNA binding
DMI74_07515	COG1862	Preprotein translocase
DMI74_07520	COG0343	queuine tRNA-ribosyltransferase activity
DMI74_07525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMI74_07535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMI74_07540	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMI74_07545	COG0776	regulation of translation
DMI74_07580	COG0811	peptide transport
DMI74_07600	COG3250	beta-galactosidase activity
DMI74_07605	COG0525	valine-tRNA ligase activity
DMI74_07620	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMI74_07625	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMI74_07630	COG0255	Belongs to the universal ribosomal protein uL29 family
DMI74_07635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMI74_07640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMI74_07645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMI74_07655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMI74_07660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMI74_07665	COG0089	rRNA binding
DMI74_07670	COG0088	Forms part of the polypeptide exit tunnel
DMI74_07675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMI74_07680	COG0051	transcription antitermination factor activity, RNA binding
DMI74_07685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMI74_07690	COG0049	tRNA binding
DMI74_07695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMI74_07705	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMI74_07715	COG3852	Histidine kinase
DMI74_07720	COG2204	response regulator
DMI74_07730	COG1722	exodeoxyribonuclease VII activity
DMI74_07735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI74_07750	COG0795	lipopolysaccharide-transporting ATPase activity
DMI74_07755	COG1160	GTP binding
DMI74_07760	COG0444	Belongs to the ABC transporter superfamily
DMI74_07780	COG1136	(ABC) transporter
DMI74_07780	COG0577	efflux transmembrane transporter activity
DMI74_07790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI74_07840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMI74_07850	COG0799	negative regulation of ribosome biogenesis
DMI74_07855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMI74_07915	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DMI74_07930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DMI74_07940	COG0300	oxidoreductase activity
DMI74_07960	COG0038	chloride channel
DMI74_07970	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_07985	COG0076	glutamate decarboxylase activity
DMI74_08000	COG0167	dihydroorotate dehydrogenase activity
DMI74_08005	COG0352	thiamine-phosphate diphosphorylase activity
DMI74_08025	COG1253	flavin adenine dinucleotide binding
DMI74_08030	COG1253	flavin adenine dinucleotide binding
DMI74_08040	COG1185	polyribonucleotide nucleotidyltransferase activity
DMI74_08045	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMI74_08050	COG0110	maltose O-acetyltransferase activity
DMI74_08075	COG0101	tRNA pseudouridine synthase activity
DMI74_08080	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMI74_08100	COG4968	Prepilin-type N-terminal cleavage methylation domain
DMI74_08115	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_08120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMI74_08140	COG1136	(ABC) transporter
DMI74_08145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMI74_08155	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI74_08180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_08185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMI74_08190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMI74_08205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DMI74_08210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMI74_08225	COG2814	Major facilitator Superfamily
DMI74_08240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI74_08245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI74_08245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI74_08250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMI74_08255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMI74_08260	COG0552	protein localization to endoplasmic reticulum
DMI74_08265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMI74_08285	COG1058	Belongs to the CinA family
DMI74_08285	COG1546	Belongs to the CinA family
DMI74_08295	COG0456	acetyltransferase
DMI74_08320	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMI74_08325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMI74_08330	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMI74_08335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI74_08350	COG0758	DNA mediated transformation
DMI74_08355	COG1686	Belongs to the peptidase S11 family
DMI74_08360	COG0012	GTP binding
DMI74_08365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMI74_08375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI74_08375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI74_08390	COG3119	arylsulfatase activity
DMI74_08420	COG2259	Doxx family
DMI74_08425	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMI74_08455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI74_08475	COG2326	polyphosphate kinase activity
DMI74_08480	COG1349	DNA-binding transcription factor activity
DMI74_08495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI74_08500	COG1162	GTPase activity
DMI74_08515	COG0742	ribosomal rna small subunit methyltransferase
DMI74_08530	COG2326	polyphosphate kinase activity
DMI74_08545	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI74_08555	COG1073	alpha beta
DMI74_08560	COG0802	atpase or kinase
DMI74_08565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMI74_08570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMI74_08575	COG0735	belongs to the Fur family
DMI74_08580	COG0396	ATPase activity
DMI74_08585	COG0719	Fe-S assembly protein
DMI74_08590	COG0719	Fe-S assembly protein
DMI74_08605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMI74_08645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMI74_08665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMI74_08670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMI74_08675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMI74_08680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMI74_08685	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMI74_08690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMI74_08700	COG0356	it plays a direct role in the translocation of protons across the membrane
DMI74_08755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMI74_08780	COG1045	serine acetyltransferase
DMI74_08785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMI74_08790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMI74_08795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMI74_08805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMI74_08815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMI74_08820	COG0047	phosphoribosylformylglycinamidine synthase activity
DMI74_08830	COG1363	Peptidase, m42
DMI74_08845	COG1077	Cell shape determining protein MreB Mrl
DMI74_08850	COG1530	ribonuclease E activity
DMI74_08880	COG0848	biopolymer transport protein
DMI74_08900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMI74_08920	COG0134	indole-3-glycerol-phosphate synthase activity
DMI74_08925	COG0792	nuclease activity
DMI74_08935	COG1253	flavin adenine dinucleotide binding
DMI74_08945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMI74_08960	COG0137	argininosuccinate synthase activity
DMI74_08975	COG0149	triose-phosphate isomerase activity
DMI74_09010	COG1040	competence protein
DMI74_09020	COG3956	TIGRFAM MazG family protein
DMI74_09040	COG1663	tetraacyldisaccharide 4'-kinase activity
DMI74_09050	COG0612	Peptidase, M16
DMI74_09070	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI74_09075	COG0583	DNA-binding transcription factor activity
DMI74_09105	COG0673	inositol 2-dehydrogenase activity
DMI74_09110	COG3034	peptidoglycan biosynthetic process
DMI74_09130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMI74_09135	COG0424	maF-like protein
DMI74_09140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMI74_09145	COG2815	serine threonine protein kinase
DMI74_09145	COG0515	serine threonine protein kinase
DMI74_09170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMI74_09180	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMI74_09190	COG0571	ribonuclease III activity
DMI74_09210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMI74_09225	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMI74_09245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI74_09260	COG2226	methyltransferase
DMI74_09270	COG2076	Multidrug Resistance protein
DMI74_09495	COG2255	four-way junction helicase activity
DMI74_09500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMI74_09505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI74_09510	COG1215	transferase activity, transferring glycosyl groups
DMI74_09515	COG0463	Glycosyl transferase, family 2
DMI74_09515	COG1216	Glycosyl transferase, family 2
DMI74_09540	COG0438	transferase activity, transferring glycosyl groups
DMI74_09550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI74_09560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMI74_09575	COG0482	sulfurtransferase activity
DMI74_09580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMI74_09590	COG2860	membrane
DMI74_09595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI74_09600	COG2001	Belongs to the MraZ family
DMI74_09605	COG0275	rRNA processing
DMI74_09615	COG0768	penicillin binding
DMI74_09620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMI74_09625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMI74_09630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMI74_09635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMI74_09645	COG0772	Belongs to the SEDS family
DMI74_09650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMI74_09655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI74_09660	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMI74_09670	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMI74_09675	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI74_09680	COG0321	lipoyl(octanoyl) transferase activity
DMI74_09685	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMI74_09690	COG0066	3-isopropylmalate dehydratase activity
DMI74_09700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI74_09710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI74_09720	COG4608	Belongs to the ABC transporter superfamily
DMI74_09725	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMI74_09740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DMI74_09755	COG1137	ATPase activity
DMI74_09765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI74_09790	COG0017	Asparaginyl-tRNA synthetase
DMI74_09800	COG3118	belongs to the thioredoxin family
DMI74_09850	COG0583	DNA-binding transcription factor activity
DMI74_09855	COG2855	membrane
DMI74_09860	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMI74_09875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMI74_09885	COG0602	queuosine metabolic process
DMI74_09890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI74_09895	COG0217	transcriptional regulatory protein
DMI74_09900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMI74_09905	COG4651	solute:proton antiporter activity
DMI74_09905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI74_09915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMI74_09920	COG4864	UPF0365 protein
DMI74_09930	COG2022	thiamine diphosphate biosynthetic process
DMI74_09935	COG0531	amino acid
DMI74_09945	COG0628	permease
DMI74_09950	COG0019	diaminopimelate decarboxylase activity
DMI74_09955	COG0191	fructose-bisphosphate aldolase activity
DMI74_09995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMI74_10025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI74_10030	COG0517	IMP dehydrogenase activity
DMI74_10030	COG0516	GMP reductase activity
DMI74_10035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI74_10035	COG0519	Catalyzes the synthesis of GMP from XMP
DMI74_10045	COG0546	phosphoglycolate phosphatase activity
DMI74_10065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DMI74_10080	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMI74_10085	COG0196	riboflavin kinase activity
DMI74_10090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMI74_10105	COG1408	metallophosphoesterase
DMI74_10115	COG1216	Glycosyl transferase, family 2
DMI74_10115	COG1442	glycosyl transferase family 8
DMI74_10125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI74_10130	COG1216	Glycosyl transferase, family 2
DMI74_10150	COG2755	lipolytic protein G-D-S-L family
DMI74_10150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI74_10170	COG0490	domain, Protein
DMI74_10170	COG0471	metal ion transport
DMI74_10210	COG0588	phosphoglycerate mutase activity
DMI74_10215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMI74_10225	COG0477	Major facilitator Superfamily
DMI74_10230	COG1607	acyl-coa hydrolase
DMI74_10250	COG1525	nuclease
DMI74_10265	COG1475	DNA binding
DMI74_10270	COG3969	phosphoadenosine phosphosulfate
DMI74_10350	COG3015	lipoprotein NlpE involved in copper resistance
DMI74_10420	COG0305	Participates in initiation and elongation during chromosome replication
DMI74_10525	COG0473	3-isopropylmalate dehydrogenase activity
DMI74_10550	COG2873	o-acetylhomoserine
DMI74_10555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMI74_10560	COG0535	radical SAM domain protein
DMI74_10575	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI74_10580	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DMI74_10590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMI74_10600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMI74_10600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMI74_10600	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMI74_10600	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMI74_10610	COG1733	regulation of RNA biosynthetic process
DMI74_10620	COG0107	imidazoleglycerol-phosphate synthase activity
DMI74_10630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI74_10640	COG1643	Atp-dependent helicase
DMI74_10645	COG0440	acetolactate synthase activity
DMI74_10650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI74_10660	COG0445	tRNA wobble uridine modification
DMI74_10670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI74_10670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI74_10675	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMI74_10685	COG0592	DNA-directed DNA polymerase activity
DMI74_10710	COG1388	LysM domain
DMI74_10710	COG0791	NLP P60 protein
DMI74_10715	COG0084	hydrolase, TatD family'
DMI74_10725	COG3250	beta-galactosidase activity
DMI74_10740	COG2205	protein histidine kinase activity
DMI74_10745	COG0745	RESPONSE REGULATOR receiver
DMI74_10755	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI74_10765	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI74_10785	COG0542	response to heat
DMI74_10835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMI74_10845	COG0659	secondary active sulfate transmembrane transporter activity
DMI74_10850	COG0165	Argininosuccinate lyase
DMI74_10865	COG0148	phosphopyruvate hydratase activity
DMI74_10870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMI74_10880	COG3481	metal-dependent phosphohydrolase, HD sub domain
DMI74_10890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI74_10895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMI74_10945	COG2985	domain, Protein
DMI74_10945	COG0490	domain, Protein
DMI74_10960	COG0471	metal ion transport
DMI74_10985	COG2194	sulfuric ester hydrolase activity
DMI74_10995	COG1592	Rubrerythrin
DMI74_11005	COG1363	Peptidase, m42
DMI74_11010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI74_11020	COG1785	Belongs to the alkaline phosphatase family
DMI74_11025	COG1970	mechanosensitive ion channel activity
DMI74_11030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMI74_11040	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMI74_11050	COG2217	Heavy metal translocating P-type atpase
DMI74_11055	COG0497	DNA recombination
DMI74_11060	COG0321	lipoyl(octanoyl) transferase activity
DMI74_11060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DMI74_11065	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DMI74_11095	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI74_11100	COG0022	dehydrogenase e1 component
DMI74_11105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI74_11115	COG0789	Transcriptional regulator
DMI74_11120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI74_11125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI74_11130	COG3210	domain, Protein
DMI74_11180	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI74_11180	COG3409	Peptidoglycan-binding domain 1 protein
DMI74_11185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMI74_11210	COG1690	Belongs to the RtcB family
DMI74_11220	COG2814	Major facilitator Superfamily
DMI74_11230	COG2096	Adenosyltransferase
DMI74_11240	COG0557	exoribonuclease II activity
DMI74_11250	COG0826	peptidase U32
DMI74_11255	COG0285	dihydrofolate synthase activity
DMI74_11270	COG0673	inositol 2-dehydrogenase activity
DMI74_11275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI74_11280	COG0737	Belongs to the 5'-nucleotidase family
DMI74_11290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMI74_11295	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMI74_11310	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMI74_11315	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMI74_11320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMI74_11325	COG0200	Binds to the 23S rRNA
DMI74_11330	COG0201	protein transport
DMI74_11335	COG0563	adenylate kinase activity
DMI74_11340	COG0024	Methionine aminopeptidase
DMI74_11355	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMI74_11360	COG1442	glycosyl transferase family 8
DMI74_11370	COG1216	Glycosyl transferase, family 2
DMI74_11380	COG1216	Glycosyl transferase, family 2
DMI74_11395	COG1216	Glycosyl transferase, family 2
DMI74_11400	COG0693	protein deglycase activity
DMI74_11405	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI74_11410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMI74_11415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI74_11425	COG1966	Carbon starvation protein
DMI74_11440	COG3119	arylsulfatase activity
DMI74_11445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMI74_11450	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMI74_11455	COG0195	Participates in both transcription termination and antitermination
DMI74_11460	COG0708	Exodeoxyribonuclease III
DMI74_11465	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMI74_11470	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMI74_11475	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMI74_11485	COG1131	(ABC) transporter
DMI74_11485	COG1716	ATPase activity
DMI74_11485	COG0842	Transport permease protein
DMI74_11505	COG0724	RNA recognition motif
DMI74_11510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI74_11530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMI74_11540	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMI74_11545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMI74_11560	COG1490	D-aminoacyl-tRNA deacylase activity
DMI74_11575	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMI74_11580	COG1053	succinate dehydrogenase
DMI74_11630	COG1028	Short-chain dehydrogenase reductase Sdr
DMI74_11640	COG0488	(ABC) transporter
DMI74_11650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMI74_11660	COG1253	flavin adenine dinucleotide binding
DMI74_11665	COG1028	Short-chain dehydrogenase reductase Sdr
DMI74_11675	COG1073	alpha beta
DMI74_11685	COG0667	Aldo Keto reductase
DMI74_11740	COG2267	carboxylic ester hydrolase activity
DMI74_11745	COG2095	MarC family integral membrane protein
DMI74_11785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI74_11790	COG0488	(ABC) transporter
DMI74_11800	COG0697	spore germination
DMI74_11810	COG0215	cysteine-tRNA ligase activity
DMI74_11820	COG3119	arylsulfatase activity
DMI74_11830	COG0481	GTPase activity
DMI74_11850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMI74_11855	COG0085	RNA polymerase activity
DMI74_11860	COG0222	ribosome binding
DMI74_11865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMI74_11870	COG0081	regulation of translation
DMI74_11875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMI74_11880	COG0250	Participates in transcription elongation, termination and antitermination
DMI74_11895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMI74_11915	COG0740	serine-type endopeptidase activity
DMI74_11920	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMI74_11935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMI74_11955	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI74_12000	COG2226	methyltransferase
DMI74_12005	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMI74_12010	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMI74_12030	COG1902	pentaerythritol trinitrate reductase activity
DMI74_12030	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMI74_12040	COG3119	arylsulfatase activity
DMI74_12045	COG0514	ATP-dependent DNA helicase (RecQ)
DMI74_12060	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMI74_12065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMI74_12130	COG1858	cytochrome C peroxidase
DMI74_12135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMI74_12140	COG0590	tRNA wobble adenosine to inosine editing
DMI74_12145	COG1940	carbohydrate kinase activity
DMI74_12150	COG2217	Heavy metal translocating P-type atpase
DMI74_12155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI74_12160	COG0237	dephospho-CoA kinase activity
DMI74_12190	COG1363	Peptidase, m42
DMI74_12195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMI74_12205	COG0006	proline dipeptidase activity
DMI74_12210	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMI74_12230	COG5002	protein histidine kinase activity
DMI74_12235	COG0745	RESPONSE REGULATOR receiver
DMI74_12240	COG0129	dihydroxy-acid dehydratase activity
DMI74_12265	COG1368	sulfuric ester hydrolase activity
DMI74_12300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMI74_12305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMI74_12330	COG0534	Mate efflux family protein
DMI74_12335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI74_12350	COG1876	peptidase activity