locus-tag	class	description
DMI81_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMI81_00010	COG1131	(ABC) transporter
DMI81_00030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMI81_00035	COG0564	pseudouridine synthase activity
DMI81_00050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DMI81_00055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMI81_00065	COG0513	Belongs to the DEAD box helicase family
DMI81_00085	COG0673	inositol 2-dehydrogenase activity
DMI81_00105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DMI81_00125	COG1971	Probably functions as a manganese efflux pump
DMI81_00155	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DMI81_00335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI81_00360	COG0442	prolyl-tRNA aminoacylation
DMI81_00395	COG0531	amino acid
DMI81_00400	COG2066	Belongs to the glutaminase family
DMI81_00415	COG1115	amino acid carrier protein
DMI81_00425	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DMI81_00430	COG2890	protein-(glutamine-N5) methyltransferase activity
DMI81_00435	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMI81_00440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DMI81_00460	COG2226	methyltransferase
DMI81_00465	COG0534	Mate efflux family protein
DMI81_00475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI81_00480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DMI81_00485	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_00505	COG1121	(ABC) transporter
DMI81_00510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMI81_00515	COG3880	PFAM UvrB UvrC protein
DMI81_00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DMI81_00525	COG0542	response to heat
DMI81_00540	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMI81_00545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI81_00560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DMI81_00560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI81_00575	COG0180	Tryptophanyl-tRNA synthetase
DMI81_00585	COG1692	metallophosphoesterase
DMI81_00595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DMI81_00610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMI81_00615	COG2816	NAD+ diphosphatase activity
DMI81_00630	COG0156	8-amino-7-oxononanoate synthase activity
DMI81_00645	COG0515	serine threonine protein kinase
DMI81_00645	COG3266	domain, Protein
DMI81_00685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMI81_00695	COG3189	MarR family transcriptional regulator
DMI81_00705	COG0181	hydroxymethylbilane synthase activity
DMI81_00710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DMI81_00720	COG1469	GTP cyclohydrolase I activity
DMI81_00725	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DMI81_00730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DMI81_00735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMI81_00740	COG1940	carbohydrate kinase activity
DMI81_00755	COG0494	nUDIX hydrolase
DMI81_00760	COG1566	PFAM secretion protein HlyD family protein
DMI81_00765	COG1136	(ABC) transporter
DMI81_00765	COG0577	efflux transmembrane transporter activity
DMI81_00770	COG1136	(ABC) transporter
DMI81_00770	COG0577	efflux transmembrane transporter activity
DMI81_00775	COG1538	Outer membrane efflux protein
DMI81_00785	COG1720	tRNA m6t6A37 methyltransferase activity
DMI81_00790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DMI81_00795	COG0540	Belongs to the ATCase OTCase family
DMI81_00800	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DMI81_00815	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DMI81_00820	COG2957	Belongs to the agmatine deiminase family
DMI81_00830	COG0750	zinc metalloprotease
DMI81_00840	COG3119	arylsulfatase activity
DMI81_00850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI81_00850	COG1918	ferrous iron import across plasma membrane
DMI81_00910	COG1475	DNA binding
DMI81_00945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMI81_00960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMI81_00965	COG0601	transmembrane transport
DMI81_01025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMI81_01030	COG1132	(ABC) transporter
DMI81_01035	COG1132	(ABC) transporter
DMI81_01050	COG1127	ABC transporter
DMI81_01055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMI81_01085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMI81_01100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DMI81_01105	COG0504	CTP synthase activity
DMI81_01110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMI81_01135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI81_01145	COG1322	Protein conserved in bacteria
DMI81_01150	COG0546	phosphoglycolate phosphatase activity
DMI81_01155	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI81_01165	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMI81_01195	COG0657	acetylesterase activity
DMI81_01195	COG2755	lipolytic protein G-D-S-L family
DMI81_01200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMI81_01220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMI81_01225	COG2267	carboxylic ester hydrolase activity
DMI81_01245	COG0335	large ribosomal subunit rRNA binding
DMI81_01255	COG0346	lactoylglutathione lyase activity
DMI81_01270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DMI81_01275	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DMI81_01280	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DMI81_01280	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DMI81_01285	COG0427	acetyl-CoA hydrolase
DMI81_01295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DMI81_01305	COG0205	6-phosphofructokinase activity
DMI81_01315	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI81_01320	COG0028	Belongs to the TPP enzyme family
DMI81_01345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMI81_01360	COG0471	metal ion transport
DMI81_01370	COG0351	phosphomethylpyrimidine kinase
DMI81_01425	COG1028	Short-chain dehydrogenase reductase Sdr
DMI81_01435	COG0242	peptide deformylase activity
DMI81_01440	COG1063	alcohol dehydrogenase
DMI81_01450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMI81_01455	COG1393	Belongs to the ArsC family
DMI81_01460	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI81_01470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DMI81_01480	COG1187	pseudouridine synthase activity
DMI81_01490	COG0336	Belongs to the RNA methyltransferase TrmD family
DMI81_01495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DMI81_01505	COG0539	negative regulation of cytoplasmic translation
DMI81_01555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DMI81_01560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMI81_01565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DMI81_01570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI81_01610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI81_01690	COG3015	lipoprotein NlpE involved in copper resistance
DMI81_01765	COG0305	Participates in initiation and elongation during chromosome replication
DMI81_01840	COG3645	SOS response
DMI81_01880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DMI81_01880	COG0662	Cupin 2, conserved barrel domain protein
DMI81_01890	COG0416	fatty acid biosynthetic process
DMI81_01895	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DMI81_01905	COG0537	adenosine 5'-monophosphoramidase activity
DMI81_01910	COG0009	L-threonylcarbamoyladenylate synthase
DMI81_01915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DMI81_01920	COG0228	four-way junction DNA binding
DMI81_01940	COG1862	Preprotein translocase
DMI81_01950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMI81_01960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMI81_01965	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMI81_01970	COG0776	regulation of translation
DMI81_02005	COG0811	peptide transport
DMI81_02025	COG3250	beta-galactosidase activity
DMI81_02030	COG0525	valine-tRNA ligase activity
DMI81_02040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DMI81_02045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DMI81_02050	COG0255	Belongs to the universal ribosomal protein uL29 family
DMI81_02055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DMI81_02060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DMI81_02065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DMI81_02075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DMI81_02080	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMI81_02085	COG0089	rRNA binding
DMI81_02090	COG0088	Forms part of the polypeptide exit tunnel
DMI81_02095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DMI81_02100	COG0051	transcription antitermination factor activity, RNA binding
DMI81_02105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DMI81_02110	COG0049	tRNA binding
DMI81_02115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DMI81_02125	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMI81_02135	COG3852	Histidine kinase
DMI81_02140	COG2204	response regulator
DMI81_02150	COG1722	exodeoxyribonuclease VII activity
DMI81_02155	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI81_02170	COG0795	lipopolysaccharide-transporting ATPase activity
DMI81_02175	COG1160	GTP binding
DMI81_02180	COG0444	Belongs to the ABC transporter superfamily
DMI81_02200	COG1136	(ABC) transporter
DMI81_02200	COG0577	efflux transmembrane transporter activity
DMI81_02210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI81_02330	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI81_02415	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DMI81_02455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DMI81_02460	COG0799	negative regulation of ribosome biogenesis
DMI81_02465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMI81_02525	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
DMI81_02540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DMI81_02550	COG0300	oxidoreductase activity
DMI81_02570	COG0038	chloride channel
DMI81_02580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_02595	COG0076	glutamate decarboxylase activity
DMI81_02610	COG0167	dihydroorotate dehydrogenase activity
DMI81_02615	COG0352	thiamine-phosphate diphosphorylase activity
DMI81_02635	COG1253	flavin adenine dinucleotide binding
DMI81_02640	COG1253	flavin adenine dinucleotide binding
DMI81_02645	COG1185	polyribonucleotide nucleotidyltransferase activity
DMI81_02650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DMI81_02655	COG0110	maltose O-acetyltransferase activity
DMI81_02680	COG0101	tRNA pseudouridine synthase activity
DMI81_02685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DMI81_02705	COG4968	Prepilin-type N-terminal cleavage methylation domain
DMI81_02720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_02730	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DMI81_02750	COG1136	(ABC) transporter
DMI81_02755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DMI81_02765	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI81_02790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_02795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DMI81_02800	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DMI81_02810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DMI81_02815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DMI81_02830	COG2814	Major facilitator Superfamily
DMI81_02840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI81_02845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI81_02845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMI81_02850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DMI81_02855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DMI81_02860	COG0552	protein localization to endoplasmic reticulum
DMI81_02865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DMI81_02885	COG1546	Belongs to the CinA family
DMI81_02885	COG1058	Belongs to the CinA family
DMI81_02895	COG0456	acetyltransferase
DMI81_02920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DMI81_02925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DMI81_02930	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMI81_02935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMI81_02950	COG0758	DNA mediated transformation
DMI81_02955	COG1686	Belongs to the peptidase S11 family
DMI81_02960	COG0012	GTP binding
DMI81_02965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DMI81_02975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI81_02975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI81_02990	COG3119	arylsulfatase activity
DMI81_03020	COG2259	Doxx family
DMI81_03025	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DMI81_03055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI81_03075	COG2326	polyphosphate kinase activity
DMI81_03080	COG1349	DNA-binding transcription factor activity
DMI81_03095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMI81_03100	COG1162	GTPase activity
DMI81_03115	COG0742	ribosomal rna small subunit methyltransferase
DMI81_03130	COG2326	polyphosphate kinase activity
DMI81_03140	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI81_03150	COG1073	alpha beta
DMI81_03155	COG0802	atpase or kinase
DMI81_03160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DMI81_03165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DMI81_03170	COG0735	belongs to the Fur family
DMI81_03175	COG0396	ATPase activity
DMI81_03180	COG0719	Fe-S assembly protein
DMI81_03185	COG0719	Fe-S assembly protein
DMI81_03205	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DMI81_03245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMI81_03265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DMI81_03270	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DMI81_03275	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DMI81_03280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DMI81_03285	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DMI81_03290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DMI81_03300	COG0356	it plays a direct role in the translocation of protons across the membrane
DMI81_03370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DMI81_03400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DMI81_03405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DMI81_03410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMI81_03420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DMI81_03430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMI81_03435	COG0047	phosphoribosylformylglycinamidine synthase activity
DMI81_03445	COG1363	Peptidase, m42
DMI81_03460	COG1077	Cell shape determining protein MreB Mrl
DMI81_03465	COG1530	ribonuclease E activity
DMI81_03490	COG0848	biopolymer transport protein
DMI81_03505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMI81_03530	COG0134	indole-3-glycerol-phosphate synthase activity
DMI81_03545	COG1253	flavin adenine dinucleotide binding
DMI81_03555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DMI81_03570	COG0137	argininosuccinate synthase activity
DMI81_03590	COG0149	triose-phosphate isomerase activity
DMI81_03625	COG1040	competence protein
DMI81_03635	COG3956	TIGRFAM MazG family protein
DMI81_03655	COG1663	tetraacyldisaccharide 4'-kinase activity
DMI81_03660	COG0612	Peptidase, M16
DMI81_03690	COG0673	inositol 2-dehydrogenase activity
DMI81_03695	COG3034	peptidoglycan biosynthetic process
DMI81_03715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMI81_03720	COG0424	maF-like protein
DMI81_03725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMI81_03730	COG2815	serine threonine protein kinase
DMI81_03730	COG0515	serine threonine protein kinase
DMI81_03755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DMI81_03765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DMI81_03775	COG0571	ribonuclease III activity
DMI81_03795	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DMI81_03810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMI81_03830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI81_03855	COG2076	Multidrug Resistance protein
DMI81_03930	COG1431	PFAM Stem cell self-renewal protein Piwi
DMI81_03945	COG2255	four-way junction helicase activity
DMI81_03950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DMI81_03955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI81_03960	COG1215	transferase activity, transferring glycosyl groups
DMI81_03965	COG1216	Glycosyl transferase, family 2
DMI81_03990	COG0438	transferase activity, transferring glycosyl groups
DMI81_04000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI81_04010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DMI81_04015	COG0482	sulfurtransferase activity
DMI81_04020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DMI81_04030	COG2860	membrane
DMI81_04035	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI81_04040	COG2001	Belongs to the MraZ family
DMI81_04045	COG0275	rRNA processing
DMI81_04055	COG0768	penicillin binding
DMI81_04060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMI81_04065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMI81_04070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DMI81_04075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DMI81_04085	COG0772	Belongs to the SEDS family
DMI81_04090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DMI81_04095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI81_04100	COG1181	Belongs to the D-alanine--D-alanine ligase family
DMI81_04110	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DMI81_04115	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI81_04120	COG0321	lipoyl(octanoyl) transferase activity
DMI81_04125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DMI81_04130	COG0066	3-isopropylmalate dehydratase activity
DMI81_04140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI81_04150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI81_04160	COG4608	Belongs to the ABC transporter superfamily
DMI81_04170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DMI81_04185	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DMI81_04200	COG1137	ATPase activity
DMI81_04210	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMI81_04235	COG0017	Asparaginyl-tRNA synthetase
DMI81_04245	COG3118	belongs to the thioredoxin family
DMI81_04295	COG0583	DNA-binding transcription factor activity
DMI81_04300	COG2855	membrane
DMI81_04305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMI81_04320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMI81_04330	COG0602	queuosine metabolic process
DMI81_04335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI81_04340	COG0217	transcriptional regulatory protein
DMI81_04350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DMI81_04355	COG4651	solute:proton antiporter activity
DMI81_04355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI81_04365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DMI81_04370	COG4864	UPF0365 protein
DMI81_04380	COG2022	thiamine diphosphate biosynthetic process
DMI81_04385	COG0531	amino acid
DMI81_04395	COG0628	permease
DMI81_04400	COG0019	diaminopimelate decarboxylase activity
DMI81_04405	COG0191	fructose-bisphosphate aldolase activity
DMI81_04440	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMI81_04470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI81_04475	COG0517	IMP dehydrogenase activity
DMI81_04475	COG0516	GMP reductase activity
DMI81_04480	COG0519	Catalyzes the synthesis of GMP from XMP
DMI81_04480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI81_04515	COG0863	Belongs to the N(4) N(6)-methyltransferase family
DMI81_04545	COG0546	phosphoglycolate phosphatase activity
DMI81_04565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DMI81_04580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DMI81_04585	COG0196	riboflavin kinase activity
DMI81_04590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMI81_04605	COG1408	metallophosphoesterase
DMI81_04615	COG1216	Glycosyl transferase, family 2
DMI81_04615	COG1442	glycosyl transferase family 8
DMI81_04625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI81_04630	COG1216	Glycosyl transferase, family 2
DMI81_04650	COG2755	lipolytic protein G-D-S-L family
DMI81_04650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI81_04670	COG0471	metal ion transport
DMI81_04670	COG0490	domain, Protein
DMI81_04710	COG0588	phosphoglycerate mutase activity
DMI81_04715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DMI81_04725	COG0477	Major facilitator Superfamily
DMI81_04730	COG1607	acyl-coa hydrolase
DMI81_04745	COG1525	nuclease
DMI81_04760	COG1475	DNA binding
DMI81_04765	COG3969	phosphoadenosine phosphosulfate
DMI81_04780	COG0473	3-isopropylmalate dehydrogenase activity
DMI81_04805	COG2873	o-acetylhomoserine
DMI81_04815	COG0535	radical SAM domain protein
DMI81_04830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DMI81_04835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DMI81_04845	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DMI81_04850	COG0674	pyruvate-flavodoxin oxidoreductase activity
DMI81_04850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMI81_04850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DMI81_04850	COG1013	pyruvate-flavodoxin oxidoreductase activity
DMI81_04860	COG1733	regulation of RNA biosynthetic process
DMI81_04870	COG0107	imidazoleglycerol-phosphate synthase activity
DMI81_04880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI81_04890	COG1643	Atp-dependent helicase
DMI81_04895	COG0440	acetolactate synthase activity
DMI81_04900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI81_04910	COG0445	tRNA wobble uridine modification
DMI81_04915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI81_04915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMI81_04920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DMI81_04930	COG0592	DNA-directed DNA polymerase activity
DMI81_04955	COG1388	LysM domain
DMI81_04955	COG0791	NLP P60 protein
DMI81_04960	COG0084	hydrolase, TatD family'
DMI81_04970	COG3250	beta-galactosidase activity
DMI81_04985	COG2205	protein histidine kinase activity
DMI81_04990	COG0745	RESPONSE REGULATOR receiver
DMI81_05000	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI81_05010	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI81_05030	COG0542	response to heat
DMI81_05075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DMI81_05085	COG0659	secondary active sulfate transmembrane transporter activity
DMI81_05090	COG0165	Argininosuccinate lyase
DMI81_05105	COG0148	phosphopyruvate hydratase activity
DMI81_05110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DMI81_05120	COG3481	metal-dependent phosphohydrolase, HD sub domain
DMI81_05130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI81_05135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DMI81_05165	COG2985	domain, Protein
DMI81_05165	COG0490	domain, Protein
DMI81_05180	COG0471	metal ion transport
DMI81_05205	COG2194	sulfuric ester hydrolase activity
DMI81_05215	COG1592	Rubrerythrin
DMI81_05225	COG1363	Peptidase, m42
DMI81_05230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_05240	COG1785	Belongs to the alkaline phosphatase family
DMI81_05245	COG1970	mechanosensitive ion channel activity
DMI81_05250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMI81_05260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DMI81_05280	COG2217	Heavy metal translocating P-type atpase
DMI81_05285	COG0497	DNA recombination
DMI81_05290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DMI81_05290	COG0321	lipoyl(octanoyl) transferase activity
DMI81_05295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DMI81_05325	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI81_05330	COG0022	dehydrogenase e1 component
DMI81_05335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DMI81_05350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI81_05355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI81_05415	COG3409	Peptidoglycan-binding domain 1 protein
DMI81_05415	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI81_05420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMI81_05450	COG1690	Belongs to the RtcB family
DMI81_05460	COG2814	Major facilitator Superfamily
DMI81_05470	COG2096	Adenosyltransferase
DMI81_05480	COG0557	exoribonuclease II activity
DMI81_05490	COG0826	peptidase U32
DMI81_05495	COG0285	dihydrofolate synthase activity
DMI81_05510	COG0673	inositol 2-dehydrogenase activity
DMI81_05515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DMI81_05520	COG0737	Belongs to the 5'-nucleotidase family
DMI81_05530	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMI81_05535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DMI81_05550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DMI81_05555	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DMI81_05560	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DMI81_05565	COG0200	Binds to the 23S rRNA
DMI81_05570	COG0201	protein transport
DMI81_05575	COG0563	adenylate kinase activity
DMI81_05580	COG0024	Methionine aminopeptidase
DMI81_05595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DMI81_05600	COG1442	glycosyl transferase family 8
DMI81_05610	COG1216	Glycosyl transferase, family 2
DMI81_05620	COG1216	Glycosyl transferase, family 2
DMI81_05635	COG1216	Glycosyl transferase, family 2
DMI81_05640	COG0693	protein deglycase activity
DMI81_05645	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMI81_05650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DMI81_05655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI81_05665	COG1966	Carbon starvation protein
DMI81_05675	COG3119	arylsulfatase activity
DMI81_05680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DMI81_05685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DMI81_05690	COG0195	Participates in both transcription termination and antitermination
DMI81_05695	COG0708	Exodeoxyribonuclease III
DMI81_05700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DMI81_05705	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DMI81_05710	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMI81_05720	COG0842	Transport permease protein
DMI81_05720	COG1716	ATPase activity
DMI81_05720	COG1131	(ABC) transporter
DMI81_05740	COG0724	RNA recognition motif
DMI81_05745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI81_05765	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DMI81_05775	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DMI81_05780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMI81_05795	COG1490	D-aminoacyl-tRNA deacylase activity
DMI81_05810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMI81_05815	COG1053	succinate dehydrogenase
DMI81_05860	COG1028	Short-chain dehydrogenase reductase Sdr
DMI81_05870	COG0488	(ABC) transporter
DMI81_05880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DMI81_05890	COG1253	flavin adenine dinucleotide binding
DMI81_05895	COG1028	Short-chain dehydrogenase reductase Sdr
DMI81_05905	COG1073	alpha beta
DMI81_05915	COG0667	Aldo Keto reductase
DMI81_05970	COG2267	carboxylic ester hydrolase activity
DMI81_05975	COG2095	MarC family integral membrane protein
DMI81_06015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMI81_06020	COG0488	(ABC) transporter
DMI81_06035	COG0697	spore germination
DMI81_06045	COG0215	cysteine-tRNA ligase activity
DMI81_06055	COG3119	arylsulfatase activity
DMI81_06065	COG0481	GTPase activity
DMI81_06085	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DMI81_06090	COG0085	RNA polymerase activity
DMI81_06095	COG0222	ribosome binding
DMI81_06100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DMI81_06105	COG0081	regulation of translation
DMI81_06110	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DMI81_06115	COG0250	Participates in transcription elongation, termination and antitermination
DMI81_06130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DMI81_06140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DMI81_06150	COG0740	serine-type endopeptidase activity
DMI81_06155	COG0544	peptidyl-prolyl cis-trans isomerase activity
DMI81_06170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMI81_06190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMI81_06230	COG2226	methyltransferase
DMI81_06235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DMI81_06240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMI81_06255	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMI81_06255	COG1902	pentaerythritol trinitrate reductase activity
DMI81_06265	COG3119	arylsulfatase activity
DMI81_06270	COG0514	ATP-dependent DNA helicase (RecQ)
DMI81_06285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DMI81_06290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMI81_06340	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DMI81_06355	COG1858	cytochrome C peroxidase
DMI81_06360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMI81_06365	COG0590	tRNA wobble adenosine to inosine editing
DMI81_06370	COG1940	carbohydrate kinase activity
DMI81_06375	COG2217	Heavy metal translocating P-type atpase
DMI81_06380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DMI81_06385	COG0237	dephospho-CoA kinase activity
DMI81_06415	COG1363	Peptidase, m42
DMI81_06420	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DMI81_06435	COG0006	proline dipeptidase activity
DMI81_06440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMI81_06455	COG5002	protein histidine kinase activity
DMI81_06460	COG0745	RESPONSE REGULATOR receiver
DMI81_06465	COG0129	dihydroxy-acid dehydratase activity
DMI81_06490	COG1368	sulfuric ester hydrolase activity
DMI81_06530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMI81_06535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMI81_06560	COG0534	Mate efflux family protein
DMI81_06565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMI81_06580	COG1876	peptidase activity
DMI81_06625	COG3209	COG3209 Rhs family protein
DMI81_06665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMI81_06670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMI81_06675	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DMI81_06680	COG2205	protein histidine kinase activity
DMI81_06690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI81_06700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI81_06710	COG0515	serine threonine protein kinase
DMI81_06715	COG0667	Aldo Keto reductase
DMI81_06720	COG0789	Transcriptional regulator
DMI81_06770	COG0714	Associated with various cellular activities
DMI81_06775	COG2311	Membrane
DMI81_06800	COG1090	epimerase
DMI81_06815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DMI81_06820	COG1119	ATPase activity
DMI81_06825	COG2186	Transcriptional regulator
DMI81_06850	COG0148	phosphopyruvate hydratase activity
DMI81_06855	COG0436	Aminotransferase
DMI81_06860	COG1477	protein flavinylation
DMI81_06875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DMI81_06885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMI81_06905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DMI81_06915	COG1199	ATP-dependent helicase activity
DMI81_06920	COG1122	ATPase activity
DMI81_06945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DMI81_06950	COG0598	Magnesium transport protein CorA
DMI81_06955	COG0359	binds to the 23S rRNA
DMI81_06960	COG0138	bifunctional purine biosynthesis protein purh
DMI81_06965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMI81_06970	COG0736	holo-[acyl-carrier-protein] synthase activity
DMI81_06980	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DMI81_06985	COG5632	N-Acetylmuramoyl-L-alanine amidase
DMI81_06985	COG3409	Peptidoglycan-binding domain 1 protein
DMI81_06990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMI81_07000	COG0437	4 iron, 4 sulfur cluster binding
DMI81_07020	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DMI81_07075	COG0284	orotidine-5'-phosphate decarboxylase activity
DMI81_07095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DMI81_07100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMI81_07120	COG2003	Belongs to the UPF0758 family
DMI81_07125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMI81_07125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMI81_07130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DMI81_07140	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DMI81_07145	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMI81_07150	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DMI81_07155	COG0322	excinuclease ABC activity
DMI81_07160	COG0811	peptide transport
DMI81_07165	COG0848	biopolymer transport protein
DMI81_07175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DMI81_07185	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DMI81_07195	COG1482	cell wall glycoprotein biosynthetic process
DMI81_07205	COG1757	Na H antiporter
DMI81_07210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI81_07215	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DMI81_07220	COG0505	Belongs to the CarA family
DMI81_07225	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DMI81_07235	COG0067	glutamate synthase
DMI81_07235	COG0069	glutamate synthase activity
DMI81_07235	COG0070	glutamate synthase
DMI81_07245	COG0706	membrane insertase activity
DMI81_07250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DMI81_07260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DMI81_07275	COG2755	lipolytic protein G-D-S-L family
DMI81_07275	COG0657	acetylesterase activity
DMI81_07285	COG0676	glucose-6-phosphate 1-epimerase activity
DMI81_07290	COG0259	pyridoxamine-phosphate oxidase activity
DMI81_07305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DMI81_07355	COG1760	l-serine dehydratase
DMI81_07360	COG0492	ferredoxin-NADP+ reductase activity
DMI81_07360	COG3118	belongs to the thioredoxin family
DMI81_07410	COG1408	metallophosphoesterase
DMI81_07420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMI81_07425	COG0545	Peptidyl-prolyl cis-trans isomerase
DMI81_07445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DMI81_07455	COG0826	peptidase U32
DMI81_07465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMI81_07495	COG0581	inorganic phosphate transmembrane transporter activity
DMI81_07500	COG0573	inorganic phosphate transmembrane transporter activity
DMI81_07510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMI81_07520	COG2017	converts alpha-aldose to the beta-anomer
DMI81_07535	COG0612	Peptidase, M16
DMI81_07595	COG0233	cytoplasmic translational termination
DMI81_07600	COG0528	UMP kinase activity
DMI81_07605	COG0668	transmembrane transport
DMI81_07610	COG0450	alkyl hydroperoxide reductase
DMI81_07615	COG0733	neurotransmitter:sodium symporter activity
DMI81_07630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMI81_07640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMI81_07645	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DMI81_07650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMI81_07675	COG0842	Transport permease protein
DMI81_07680	COG0842	Transport permease protein
DMI81_07685	COG1131	(ABC) transporter
DMI81_07695	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DMI81_07700	COG1183	phosphatidylcholine synthase activity
DMI81_07710	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMI81_07720	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DMI81_07725	COG1028	Short-chain dehydrogenase reductase Sdr
DMI81_07745	COG0156	8-amino-7-oxononanoate synthase activity
DMI81_07770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DMI81_07775	COG0124	histidyl-tRNA synthetase
DMI81_07780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DMI81_07785	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DMI81_07790	COG0298	carbon dioxide binding
DMI81_07825	COG0443	Heat shock 70 kDa protein
DMI81_07830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DMI81_07835	COG0459	protein refolding
DMI81_07885	COG0632	four-way junction helicase activity
DMI81_07895	COG0126	phosphoglycerate kinase activity
DMI81_07905	COG1082	Xylose isomerase domain protein TIM barrel
DMI81_07910	COG4991	sh3 domain protein
DMI81_07910	COG3064	Membrane
DMI81_07910	COG0515	serine threonine protein kinase
DMI81_07915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMI81_07925	COG2271	Major facilitator Superfamily
DMI81_07940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DMI81_07950	COG0037	tRNA processing
DMI81_07955	COG0254	rRNA binding
DMI81_07990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DMI81_07995	COG0039	L-malate dehydrogenase activity
DMI81_08020	COG0778	Nitroreductase
DMI81_08025	COG0564	pseudouridine synthase activity
DMI81_08045	COG1126	abc transporter atp-binding protein
DMI81_08050	COG0765	amino acid transport
DMI81_08060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DMI81_08065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMI81_08090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI81_08115	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DMI81_08120	COG1872	DUF167
DMI81_08125	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMI81_08130	COG0484	heat shock protein binding
DMI81_08135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMI81_08145	COG5434	Belongs to the glycosyl hydrolase 28 family
DMI81_08160	COG0277	FAD linked oxidase domain protein
DMI81_08185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMI81_08190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DMI81_08205	COG0131	Imidazoleglycerol-phosphate dehydratase
DMI81_08210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMI81_08215	COG0360	Binds together with S18 to 16S ribosomal RNA
DMI81_08225	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DMI81_08240	COG1686	Belongs to the peptidase S11 family
DMI81_08245	COG0205	6-phosphofructokinase activity
DMI81_08255	COG0428	transporter
DMI81_08260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DMI81_08275	COG3977	Valine--pyruvate aminotransferase
DMI81_08280	COG1561	YicC-like family, N-terminal region
DMI81_08290	COG3273	potassium ion transport
DMI81_08290	COG0471	metal ion transport
DMI81_08295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI81_08310	COG1575	Belongs to the MenA family. Type 1 subfamily
DMI81_08350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI81_08350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMI81_08375	COG0202	RNA polymerase activity
DMI81_08380	COG0203	ribosomal protein L17
DMI81_08385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMI81_08395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI81_08410	COG2885	chlorophyll binding
DMI81_08470	COG0667	Aldo Keto reductase
DMI81_08475	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMI81_08495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI81_08500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMI81_08505	COG0134	indole-3-glycerol-phosphate synthase activity
DMI81_08510	COG0135	phosphoribosylanthranilate isomerase activity
DMI81_08520	COG0159	tryptophan synthase activity
DMI81_08540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMI81_08545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DMI81_08555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DMI81_08585	COG0561	phosphatase activity
DMI81_08590	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI81_08595	COG2223	nitrite transmembrane transporter activity
DMI81_08615	COG0556	nucleotide-excision repair
DMI81_08620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DMI81_08625	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DMI81_08645	COG1074	ATP-dependent DNA helicase activity
DMI81_08655	COG0697	spore germination
DMI81_08665	COG1002	Type II restriction enzyme, methylase subunits
DMI81_08670	COG1061	Type III restriction enzyme res subunit
DMI81_08675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMI81_08680	COG2373	Large extracellular alpha-helical protein
DMI81_08685	COG1979	alcohol dehydrogenase
DMI81_08695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMI81_08720	COG0372	Belongs to the citrate synthase family
DMI81_08735	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DMI81_08745	COG1187	pseudouridine synthase activity
DMI81_08755	COG0105	UTP biosynthetic process
DMI81_08760	COG1215	transferase activity, transferring glycosyl groups
DMI81_08765	COG0463	Glycosyl transferase, family 2
DMI81_08775	COG1459	type II secretion system
DMI81_08780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMI81_08790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI81_08805	COG0728	peptidoglycan biosynthetic process
DMI81_08810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DMI81_08810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI81_08825	COG1649	PFAM Uncharacterised BCR, COG1649
DMI81_08830	COG1691	(AIR) carboxylase
DMI81_08835	COG0482	sulfurtransferase activity
DMI81_08840	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DMI81_08845	COG0142	geranyltranstransferase activity
DMI81_08860	COG2151	metal-sulfur cluster biosynthetic enzyme
DMI81_08875	COG1007	ATP synthesis coupled electron transport
DMI81_08880	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI81_08890	COG0713	ATP synthesis coupled electron transport
DMI81_08895	COG0839	Belongs to the complex I subunit 6 family
DMI81_08905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DMI81_08910	COG1034	ATP synthesis coupled electron transport
DMI81_08915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI81_08920	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DMI81_08925	COG0649	NAD binding
DMI81_08935	COG0726	polysaccharide deacetylase
DMI81_08945	COG0307	riboflavin synthase, alpha
DMI81_08955	COG2264	protein methyltransferase activity
DMI81_08965	COG3210	domain, Protein
DMI81_08970	COG1640	4-alpha-glucanotransferase
DMI81_08985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DMI81_08990	COG1030	water channel activity
DMI81_08995	COG0358	DNA primase activity
DMI81_09000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DMI81_09005	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
DMI81_09020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DMI81_09025	COG0793	Belongs to the peptidase S41A family
DMI81_09040	COG1643	Atp-dependent helicase
DMI81_09065	COG1450	Type ii and iii secretion system protein
DMI81_09080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DMI81_09100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMI81_09105	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DMI81_09115	COG0268	Binds directly to 16S ribosomal RNA
DMI81_09120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMI81_09125	COG0028	Belongs to the TPP enzyme family
DMI81_09130	COG0305	Participates in initiation and elongation during chromosome replication
DMI81_09240	COG0860	N-Acetylmuramoyl-L-alanine amidase
DMI81_09535	COG0688	phosphatidylethanolamine metabolic process
DMI81_09540	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMI81_09545	COG0495	leucyl-tRNA aminoacylation
DMI81_09550	COG3119	arylsulfatase activity
DMI81_09565	COG1166	arginine decarboxylase activity
DMI81_09575	COG3250	beta-galactosidase activity
DMI81_09580	COG3250	beta-galactosidase activity
DMI81_09585	COG3250	beta-galactosidase activity
DMI81_09590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DMI81_09595	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_09610	COG0205	6-phosphofructokinase activity
DMI81_09645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DMI81_09650	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMI81_09655	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DMI81_09670	COG4771	TonB-dependent receptor
DMI81_09690	COG0402	S-adenosylhomocysteine deaminase activity
DMI81_09695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMI81_09720	COG1294	oxidase, subunit
DMI81_09725	COG1271	oxidase subunit
DMI81_09735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMI81_09755	COG1846	Transcriptional regulator
DMI81_09780	COG2949	membrane
DMI81_09810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DMI81_10010	COG0514	ATP-dependent DNA helicase (RecQ)
DMI81_10180	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DMI81_10185	COG0045	succinate-CoA ligase (ADP-forming) activity
DMI81_10190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMI81_10255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMI81_10260	COG2205	protein histidine kinase activity
DMI81_10275	COG0113	porphobilinogen synthase activity
DMI81_10290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DMI81_10310	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DMI81_10355	COG3475	LICD family
DMI81_10360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DMI81_10370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI81_10375	COG3475	LICD family
DMI81_10380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DMI81_10390	COG2166	iron-sulfur cluster assembly
DMI81_10395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DMI81_10405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI81_10410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMI81_10415	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DMI81_10420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DMI81_10425	COG1131	(ABC) transporter
DMI81_10440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DMI81_10455	COG1215	transferase activity, transferring glycosyl groups
DMI81_10465	COG2967	ApaG domain
DMI81_10475	COG1522	sequence-specific DNA binding
DMI81_10480	COG0436	Aminotransferase
DMI81_10495	COG0423	glycine-tRNA ligase activity
DMI81_10500	COG0656	L-ascorbic acid biosynthetic process
DMI81_10515	COG2304	oxidoreductase activity
DMI81_10530	COG0714	Associated with various cellular activities
DMI81_10535	COG0154	amidase activity
DMI81_10540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMI81_10575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI81_10580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI81_10590	COG2755	lipolytic protein G-D-S-L family
DMI81_10590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI81_10615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI81_10625	COG0656	L-ascorbic acid biosynthetic process
DMI81_10635	COG0667	Aldo Keto reductase
DMI81_10640	COG1408	metallophosphoesterase
DMI81_10660	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMI81_10665	COG0789	Transcriptional regulator
DMI81_10680	COG0534	Mate efflux family protein
DMI81_10705	COG1091	dTDP-4-dehydrorhamnose reductase activity
DMI81_10720	COG1837	Belongs to the UPF0109 family
DMI81_10730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI81_10735	COG0363	glucosamine-6-phosphate deaminase activity
DMI81_10750	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DMI81_10760	COG1741	Belongs to the pirin family
DMI81_10780	COG1070	Carbohydrate kinase
DMI81_10795	COG0738	Major facilitator superfamily
DMI81_10810	COG1595	DNA-templated transcription, initiation
DMI81_10835	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DMI81_10855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMI81_10865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DMI81_10870	COG2132	Multicopper oxidase
DMI81_10875	COG0697	spore germination
DMI81_10880	COG3586	endonuclease activity
DMI81_10895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI81_10900	COG4608	Belongs to the ABC transporter superfamily
DMI81_10905	COG0444	Belongs to the ABC transporter superfamily
DMI81_10910	COG4166	transmembrane transport
DMI81_10915	COG4239	(ABC) transporter, permease
DMI81_10920	COG0601	transmembrane transport
DMI81_10940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DMI81_10945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DMI81_10950	COG3738	Protein conserved in bacteria
DMI81_10955	COG0151	Belongs to the GarS family
DMI81_10970	COG0811	peptide transport
DMI81_10980	COG0242	peptide deformylase activity
DMI81_11015	COG2010	Cytochrome c
DMI81_11025	COG3258	Cytochrome c
DMI81_11040	COG3274	enterobacterial common antigen metabolic process
DMI81_11045	COG0538	isocitrate dehydrogenase activity
DMI81_11065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DMI81_11070	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DMI81_11075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMI81_11085	COG0668	transmembrane transport
DMI81_11090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMI81_11090	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DMI81_11095	COG0805	protein transport
DMI81_11100	COG1968	undecaprenyl-diphosphatase activity
DMI81_11120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMI81_11130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMI81_11140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DMI81_11150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMI81_11160	COG1408	metallophosphoesterase
DMI81_11185	COG4974	Belongs to the 'phage' integrase family
DMI81_11210	COG1454	alcohol dehydrogenase
DMI81_11215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DMI81_11230	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DMI81_11230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DMI81_11235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMI81_11270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI81_11280	COG4607	ABC-type enterochelin transport system periplasmic component
DMI81_11285	COG4604	ABC transporter, ATP-binding protein
DMI81_11290	COG4605	iron ion homeostasis
DMI81_11295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMI81_11330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI81_11330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DMI81_11345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMI81_11355	COG2195	Cleaves the N-terminal amino acid of tripeptides
DMI81_11375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMI81_11395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMI81_11420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMI81_11420	COG0519	Catalyzes the synthesis of GMP from XMP
DMI81_11425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMI81_11460	COG1410	methionine synthase
DMI81_11460	COG0646	methionine synthase
DMI81_11465	COG2966	Psort location CytoplasmicMembrane, score
DMI81_11470	COG3610	response to peptide
DMI81_11475	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DMI81_11495	COG3177	Filamentation induced by cAMP protein fic
DMI81_11500	COG4974	Belongs to the 'phage' integrase family
DMI81_11510	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DMI81_11525	COG0460	homoserine dehydrogenase
DMI81_11530	COG0527	aspartate kinase activity
DMI81_11545	COG5522	Integral membrane protein (intg_mem_TP0381)
DMI81_11560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMI81_11575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DMI81_11580	COG1194	a g-specific adenine glycosylase
DMI81_11585	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMI81_11590	COG0574	Belongs to the PEP-utilizing enzyme family
DMI81_11590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMI81_11600	COG0166	Belongs to the GPI family
DMI81_11610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DMI81_11620	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI81_11620	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DMI81_11655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DMI81_11660	COG2818	Glycosylase
DMI81_11680	COG3033	Beta-eliminating lyase
DMI81_11695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI81_11695	COG0072	phenylalanine-tRNA ligase activity
DMI81_11715	COG0326	Molecular chaperone. Has ATPase activity
DMI81_11720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMI81_11730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMI81_11735	COG1959	2 iron, 2 sulfur cluster binding
DMI81_11750	COG0352	thiamine-phosphate diphosphorylase activity
DMI81_11755	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DMI81_11780	COG1703	isobutyryl-CoA mutase activity
DMI81_11800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DMI81_11810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMI81_11815	COG0418	dihydroorotase activity
DMI81_11830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI81_11850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMI81_11865	COG0534	Mate efflux family protein
DMI81_11870	COG0489	protein tyrosine kinase activity
DMI81_11885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMI81_11890	COG0339	signal peptide processing
DMI81_11895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMI81_11905	COG1538	Outer membrane efflux protein
DMI81_11925	COG4112	unkown
DMI81_11940	COG0038	chloride channel
DMI81_11965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMI81_11970	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMI81_11975	COG0586	Pfam SNARE associated Golgi protein
DMI81_12040	COG1518	maintenance of DNA repeat elements
DMI81_12080	COG1012	belongs to the aldehyde dehydrogenase family
DMI81_12100	COG0753	catalase activity
DMI81_12115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DMI81_12120	COG1592	Rubrerythrin
DMI81_12125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DMI81_12145	COG0489	protein tyrosine kinase activity
DMI81_12155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMI81_12165	COG2244	polysaccharide biosynthetic process
DMI81_12170	COG1215	transferase activity, transferring glycosyl groups
DMI81_12180	COG1216	Glycosyl transferase, family 2
DMI81_12190	COG0438	transferase activity, transferring glycosyl groups
DMI81_12195	COG0438	transferase activity, transferring glycosyl groups
DMI81_12225	COG1216	Glycosyl transferase, family 2
DMI81_12250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DMI81_12250	COG2755	lipolytic protein G-D-S-L family
DMI81_12270	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DMI81_12280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI81_12280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMI81_12285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DMI81_12295	COG0281	malic enzyme
DMI81_12295	COG0280	phosphate acetyltransferase
DMI81_12310	COG1472	Belongs to the glycosyl hydrolase 3 family
DMI81_12315	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DMI81_12330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMI81_12340	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DMI81_12345	COG1063	alcohol dehydrogenase
DMI81_12360	COG0714	Associated with various cellular activities
DMI81_12370	COG0193	aminoacyl-tRNA hydrolase activity
DMI81_12380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMI81_12395	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMI81_12420	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DMI81_12435	COG0375	protein maturation
DMI81_12460	COG0778	Nitroreductase
DMI81_12465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DMI81_12490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI81_12490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMI81_12510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DMI81_12515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMI81_12520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMI81_12560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI81_12565	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMI81_12580	COG0318	PFAM AMP-dependent synthetase and ligase
DMI81_12610	COG0339	signal peptide processing
DMI81_12625	COG0018	arginyl-trna synthetase
DMI81_12660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMI81_12665	COG0653	protein targeting
DMI81_12685	COG0494	nUDIX hydrolase