locus-tag	class	description
DMI67_00010	ENOG4105CBC	glutamate synthase
DMI67_00015	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DMI67_00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DMI67_00060	ENOG4105DSB	aldose 1-epimerase
DMI67_00070	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DMI67_00080	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DMI67_00095	ENOG4105EJQ	L-serine dehydratase
DMI67_00100	ENOG4105C3M	thioredoxin reductase
DMI67_00150	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DMI67_00155	ENOG4105DIN	metallophosphoesterase
DMI67_00165	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
DMI67_00170	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DMI67_00195	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DMI67_00205	ENOG4105CFP	Peptidase U32
DMI67_00210	ENOG4105E6M	Sulphatase-modifying factor protein
DMI67_00230	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
DMI67_00250	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
DMI67_00255	ENOG4105C11	sulfate adenylyltransferase), subunit 2
DMI67_00275	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
DMI67_00280	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DMI67_00285	ENOG4105E2Z	phosphate ABC transporter (Permease
DMI67_00290	ENOG4105C8U	phosphate abc transporter
DMI67_00295	ENOG4105DJH	phosphate
DMI67_00300	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DMI67_00310	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
DMI67_00325	ENOG4105C1V	Peptidase, M16
DMI67_00340	ENOG4108UW5	maltose o-acetyltransferase
DMI67_00375	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DMI67_00380	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DMI67_00390	ENOG4105D3R	alkyl hydroperoxide reductase
DMI67_00395	ENOG4105C8J	)-transporter
DMI67_00420	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DMI67_00425	ENOG4105E0X	reductase
DMI67_00430	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DMI67_00455	ENOG4107QWP	ABC-2 type transporter
DMI67_00460	ENOG4107QWP	ABC-2 type transporter
DMI67_00465	ENOG4105CJ1	ABC, transporter
DMI67_00475	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DMI67_00480	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
DMI67_00490	ENOG4105EEI	dihydropteroate synthase
DMI67_00500	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DMI67_00505	ENOG4105CHR	reductase
DMI67_00525	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DMI67_00545	ENOG4105C9M	aspartyl-trna synthetase
DMI67_00550	ENOG4105CUT	histidyl-tRNA synthetase
DMI67_00575	ENOG4105CQS	hydrogenase expression formation protein HypD
DMI67_00600	ENOG4105CFG	Acts as a chaperone (By similarity)
DMI67_00605	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
DMI67_00610	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DMI67_00645	ENOG4105D75	Capsular exopolysaccharide family
DMI67_00660	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DMI67_00670	ENOG4105BZA	Phosphoglycerate kinase
DMI67_00680	ENOG4105CGS	Alpha-glucosidase
DMI67_00690	ENOG4107YVC	modification (methylase)
DMI67_00700	ENOG4108JA2	transcriptioN-repair coupling factor
DMI67_00710	ENOG4105DJB	Major Facilitator Superfamily
DMI67_00725	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
DMI67_00730	ENOG4105C6K	Malic enzyme
DMI67_00735	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DMI67_00740	ENOG4105NRA	50s ribosomal protein l31 type b
DMI67_00775	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
DMI67_00780	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DMI67_00805	ENOG4108RCM	Nitroreductase
DMI67_00810	ENOG4105C34	Pseudouridine synthase
DMI67_00815	ENOG4105I08	Pseudouridine synthase
DMI67_00835	ENOG4105CDA	abc transporter atp-binding protein
DMI67_00840	ENOG4105E5Q	amino acid AbC transporter
DMI67_00850	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DMI67_00855	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
DMI67_00905	ENOG4105VZ9	UPF0235 protein
DMI67_00910	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DMI67_00915	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DMI67_00920	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DMI67_00930	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
DMI67_00945	ENOG4105CQB	FAD linked oxidase domain protein
DMI67_00970	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DMI67_00975	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DMI67_00985	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DMI67_00990	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DMI67_00995	ENOG4107Q5Z	Binds together with S18 to 16S ribosomal RNA (By similarity)
DMI67_01000	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
DMI67_01015	ENOG4105DZ1	carboxypeptidase
DMI67_01020	ENOG4105CTQ	phosphohexokinase
DMI67_01030	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
DMI67_01035	ENOG4105MH8	Thioredoxin disulfide isomerase
DMI67_01050	ENOG4105JKW	Valine--pyruvate aminotransferase
DMI67_01055	ENOG4105DSJ	YicC domain protein
DMI67_01070	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
DMI67_01085	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
DMI67_01110	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DMI67_01125	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DMI67_01135	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
DMI67_01145	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DMI67_01150	ENOG4108ZT0	50S ribosomal protein l17
DMI67_01155	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DMI67_01170	ENOG4107YBY	Hydrolase
DMI67_01185	ENOG4105KCK	Peptidoglycan-associated lipoprotein
DMI67_01245	ENOG4105CPC	Aldo Keto reductase
DMI67_01250	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DMI67_01265	ENOG4105CRQ	synthase (Component I)
DMI67_01270	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DMI67_01275	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DMI67_01280	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
DMI67_01285	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DMI67_01290	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DMI67_01310	ENOG4105DWV	Homoserine O-trans-acetylase
DMI67_01315	ENOG4105YK5	50S ribosomal protein L36
DMI67_01325	ENOG4105F1A	Pyruvate formate-lyase
DMI67_01360	ENOG4108HCJ	Hydrolase
DMI67_01365	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI67_01370	ENOG4106UW1	Major Facilitator superfamily
DMI67_01385	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DMI67_01390	ENOG4105VJV	50s ribosomal protein L35
DMI67_01395	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DMI67_01415	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
DMI67_01425	ENOG410631K	Membrane
DMI67_01430	ENOG4107S85	alpha-2-macroglobulin domain protein
DMI67_01435	ENOG4107QW4	alcohol dehydrogenase
DMI67_01445	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DMI67_01470	ENOG4105BZN	citrate synthase
DMI67_01495	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DMI67_01505	ENOG4108R99	pseudouridine synthase
DMI67_01515	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
DMI67_01525	ENOG4105CKK	Glycosyl transferase, family 2
DMI67_01535	ENOG4105D7Q	type ii secretion system
DMI67_01540	ENOG4107QHF	type ii secretion system protein e
DMI67_01545	ENOG4107QHF	type ii secretion system protein e
DMI67_01550	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DMI67_01565	ENOG4105CJR	Integral membrane protein (MviN
DMI67_01570	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DMI67_01580	ENOG4105F32	YngK protein
DMI67_01585	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
DMI67_01590	ENOG4105DVM	PP-loop domain protein
DMI67_01595	ENOG4105C8M	UPF0272 protein
DMI67_01600	ENOG4105EAH	synthase
DMI67_01615	ENOG4105VG1	fes assembly suf system protein
DMI67_01630	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DMI67_01635	ENOG4105C8S	subunit m
DMI67_01645	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DMI67_01650	ENOG4107UFS	subunit j
DMI67_01660	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
DMI67_01665	ENOG4108IEH	NADH dehydrogenase subunit g
DMI67_01670	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
DMI67_01675	ENOG4105GKE	subunit e
DMI67_01680	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DMI67_01690	ENOG4107BJW	polysaccharide deacetylase
DMI67_01700	ENOG4108R6K	riboflavin synthase, subunit alpha
DMI67_01710	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DMI67_01730	ENOG4107S1W	4-alpha-glucanotransferase
DMI67_01740	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
DMI67_01745	ENOG4105F7J	membrane-bound serine protease
DMI67_01750	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DMI67_01755	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DMI67_01760	ENOG4108UQS	dipeptidase
DMI67_01775	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DMI67_01780	ENOG4105CN1	protease
DMI67_01795	ENOG4105CQ7	ATP-dependent helicase
DMI67_01820	ENOG4105GVR	general secretion pathway protein D
DMI67_01835	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DMI67_01855	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
DMI67_01860	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DMI67_01870	ENOG410872P	Binds directly to 16S ribosomal RNA (By similarity)
DMI67_01875	ENOG4107VXZ	Hydrolase
DMI67_01880	ENOG4105C7K	acetolactate synthase
DMI67_01890	ENOG4105DJ4	phosphatidylserine decarboxylase
DMI67_01900	ENOG4105C8T	Leucyl-tRNA synthetase
DMI67_01905	ENOG4105ENH	Sulfatase
DMI67_01920	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
DMI67_01935	ENOG4105CNT	hydrolase family 2
DMI67_01940	ENOG4105CNT	hydrolase family 2
DMI67_01945	ENOG4105D1H	recombination factor protein RarA
DMI67_01950	ENOG4105E2D	ec 3.2.1.52
DMI67_01970	ENOG4105CTQ	phosphohexokinase
DMI67_01985	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DMI67_02020	ENOG4108YZT	Adenosylcobinamide kinase
DMI67_02030	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
DMI67_02035	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
DMI67_02040	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
DMI67_02045	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DMI67_02055	ENOG4107ENK	receptor
DMI67_02075	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
DMI67_02080	ENOG4107QN2	dihydrolipoyl dehydrogenase
DMI67_02100	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DMI67_02105	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DMI67_02115	ENOG4107WAU	Protein tyrosine phosphatase
DMI67_02135	ENOG410834F	Transcriptional regulator
DMI67_02165	ENOG4108UB4	uncharacterized protein ygjQ
DMI67_02195	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DMI67_02210	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DMI67_02215	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DMI67_02255	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DMI67_02260	ENOG4105CEY	Amp-dependent synthetase and ligase
DMI67_02285	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DMI67_02290	ENOG41065SU	Two-component system sensor kinase
DMI67_02305	ENOG4105D52	delta-aminolevulinic acid dehydratase
DMI67_02320	ENOG4105C22	threonyL-tRNA synthetase
DMI67_02325	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DMI67_02340	ENOG4107QTH	restriction modification system DNA specificity domain
DMI67_02345	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DMI67_02355	ENOG4107QTH	restriction modification system DNA specificity domain
DMI67_02365	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
DMI67_02390	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
DMI67_02405	ENOG4105KPE	licD family
DMI67_02410	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
DMI67_02425	ENOG4105KPE	licD family
DMI67_02430	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
DMI67_02440	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
DMI67_02445	ENOG4105DBV	ornithine carbamoyltransferase
DMI67_02450	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DMI67_02455	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
DMI67_02460	ENOG41080Z8	PHOSPHOCARRIER protein
DMI67_02465	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
DMI67_02470	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DMI67_02475	ENOG4105DA5	(ABC) transporter
DMI67_02490	ENOG4105DFA	alanine racemase domain protein
DMI67_02515	ENOG4105NWN	ApaG protein
DMI67_02520	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
DMI67_02520	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
DMI67_02535	ENOG4108ZB6	transcriptional regulator AsnC family
DMI67_02540	ENOG4105CHM	Aminotransferase
DMI67_02555	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
DMI67_02560	ENOG4105CV8	reductase
DMI67_02580	ENOG4107QVM	von Willebrand factor, type A
DMI67_02595	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DMI67_02600	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
DMI67_02605	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DMI67_02645	ENOG4105C0H	protease
DMI67_02660	ENOG4105EXC	Acyl-transferase
DMI67_02690	ENOG4105C87	Aminotransferase class I and II
DMI67_02700	ENOG4105CV8	reductase
DMI67_02705	ENOG4105ENX	hydrolase
DMI67_02710	ENOG4107SET	aldo keto reductase
DMI67_02715	ENOG4105DIN	metallophosphoesterase
DMI67_02735	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
DMI67_02740	ENOG4105VUF	Transcriptional regulator
DMI67_02760	ENOG4105C3S	Mate efflux family protein
DMI67_02770	ENOG4105E2D	ec 3.2.1.52
DMI67_02785	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
DMI67_02800	ENOG4105VB6	UPF0109 protein
DMI67_02810	ENOG4105DR4	Methyltransferase
DMI67_02815	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
DMI67_02830	ENOG4105DX0	Hemolysin A
DMI67_02840	ENOG4105C2I	pirin domain protein
DMI67_02855	ENOG4105CMG	Carbohydrate kinase
DMI67_02865	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
DMI67_02870	ENOG4105EDR	glucose galactose transporter
DMI67_02910	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
DMI67_02930	ENOG4105C0H	protease
DMI67_02940	ENOG4105EMK	carboxylate amino acid amine transporter
DMI67_02945	ENOG4108HFV	
DMI67_02955	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DMI67_02960	ENOG4108JQ7	(ABC) transporter
DMI67_02970	ENOG4108J59	Extracellular solute-binding protein, family 5
DMI67_02975	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
DMI67_02995	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DMI67_03000	ENOG4105CKU	formyltetrahydrofolate synthetase
DMI67_03005	ENOG4108XC3	NADH ubiquinone oxidoreductase
DMI67_03010	ENOG4107QNG	Phosphoribosylglycinamide synthetase
DMI67_03035	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DMI67_03085	ENOG4105NQN	cytochrome C
DMI67_03095	ENOG4105MEV	Acyl-transferase
DMI67_03100	ENOG4108HMX	isocitrate dehydrogenase (NADP)
DMI67_03115	ENOG4105CY0	Metallo-Beta-Lactamase
DMI67_03120	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DMI67_03125	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DMI67_03135	ENOG4105D64	Mechanosensitive ion channel
DMI67_03140	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
DMI67_03145	ENOG410845M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes (By similarity)
DMI67_03150	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DMI67_03170	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
DMI67_03180	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DMI67_03190	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DMI67_03200	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
DMI67_03210	ENOG4105DIN	metallophosphoesterase
DMI67_03230	ENOG4105DVP	Adenine-specific
DMI67_03235	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DMI67_03255	ENOG4108JB8	alcohol dehydrogenase
DMI67_03265	ENOG4105WMR	Protein CrcB homolog
DMI67_03280	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DMI67_03295	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
DMI67_03325	ENOG4105CRE	cytochrome C
DMI67_03340	ENOG4108IPW	abc transporter atp-binding protein
DMI67_03345	ENOG4105CM4	permease protein
DMI67_03350	ENOG4105DHS	permease protein
DMI67_03385	ENOG4105C2M	dna polymerase I
DMI67_03400	ENOG4105C83	adenylosuccinate lyase
DMI67_03410	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
DMI67_03430	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DMI67_03470	ENOG4108Z66	YbaK ebsC protein
DMI67_03510	ENOG4105C3R	Methionine synthase
DMI67_03515	ENOG4105DWK	Membrane
DMI67_03520	ENOG4107XM3	UPF0442 protein
DMI67_03535	ENOG4105CFH	Aspartokinase
DMI67_03555	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DMI67_03560	ENOG4105E2X	shikimate dehydrogenase
DMI67_03570	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
DMI67_03575	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DMI67_03585	ENOG4107QP8	phosphohexose isomerase
DMI67_03595	ENOG4105DR4	Methyltransferase
DMI67_03605	ENOG4105D5P	Methylmalonyl-coA mutase
DMI67_03645	ENOG4108R3E	Dna-3-methyladenine glycosylase i
DMI67_03665	ENOG4105C0F	tryptophanase EC 4.1.99.1
DMI67_03680	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DMI67_03705	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
DMI67_03730	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DMI67_03735	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
DMI67_03750	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DMI67_03755	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
DMI67_03770	ENOG4105E2D	ec 3.2.1.52
DMI67_03775	ENOG4105E2D	ec 3.2.1.52
DMI67_03780	ENOG4105DJT	lAO AO transport system ATPase
DMI67_03800	ENOG41081ID	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DMI67_03805	ENOG4105C1J	atp-dependent rna helicase
DMI67_03810	ENOG4105C5X	domain protein
DMI67_03815	ENOG4105EKE	dihydroorotase
DMI67_03830	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
DMI67_03840	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
DMI67_03850	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DMI67_03855	ENOG4107QSA	Oxaloacetate decarboxylase
DMI67_03865	ENOG4107QI1	Mate efflux family protein
DMI67_03870	ENOG4105D1F	ATP-binding protein
DMI67_03885	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DMI67_03895	ENOG4105DGW	oligopeptidase A
DMI67_03900	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
DMI67_03910	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DMI67_03930	ENOG4105U6W	MutT NUDIX family protein
DMI67_03965	ENOG4105D82	Glutamate dehydrogenase
DMI67_03975	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DMI67_03980	ENOG4107T5V	SNARE associated Golgi
DMI67_04045	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
DMI67_04060	ENOG4105FB9	CRISPR-associated protein
DMI67_04080	ENOG4105C26	Dehydrogenase
DMI67_04100	ENOG4105CH6	catalase
DMI67_04115	ENOG4105CRE	cytochrome C
DMI67_04120	ENOG4108RAC	Rubrerythrin
DMI67_04125	ENOG41068WN	
DMI67_04135	ENOG4105CNU	cell division protein FtsK
DMI67_04155	ENOG4108QV3	biosynthesis protein
DMI67_04165	ENOG4105D3Q	Sugar transferase
DMI67_04190	ENOG4105K64	Glycosyl transferase, family 2
DMI67_04205	ENOG4105E2K	Glycosyl transferase (Group 1
DMI67_04210	ENOG4107T8Q	Glycosyl transferase (Group 1
DMI67_04235	ENOG4105ECJ	Glycosyl Transferase
DMI67_04255	ENOG4105EXC	Acyl-transferase
DMI67_04275	ENOG4105C87	Aminotransferase class I and II
DMI67_04280	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DMI67_04285	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
DMI67_04290	ENOG4105C6K	Malic enzyme
DMI67_04305	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
DMI67_04325	ENOG4105CSA	Coproporphyrinogen iii oxidase
DMI67_04360	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DMI67_04365	ENOG4105CPQ	Dehydrogenase
DMI67_04380	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DMI67_04390	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DMI67_04395	ENOG4105BZ4	penicillin-binding protein
DMI67_04410	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DMI67_04430	ENOG4105E3S	small subunit
DMI67_04435	ENOG4105DPX	Hydrogenase, large subunit
DMI67_04445	ENOG4108USZ	hydrogenase
DMI67_04450	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
DMI67_04480	ENOG4108RCM	Nitroreductase
DMI67_04485	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DMI67_04520	ENOG4107GFK	fumarate
DMI67_04540	ENOG4107YVC	modification (methylase)
DMI67_04560	ENOG4105E2D	ec 3.2.1.52
DMI67_04610	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
DMI67_04615	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMI67_04630	ENOG4105CEY	Amp-dependent synthetase and ligase
DMI67_04660	ENOG4105DGW	oligopeptidase A
DMI67_04670	ENOG4105C75	arginyL-tRNA synthetase
DMI67_04705	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DMI67_04710	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DMI67_04715	ENOG4107QZM	n-acetylglutamate synthase
DMI67_04725	ENOG4108YZ4	nudix hydrolase
DMI67_04730	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DMI67_04735	ENOG4105CJ1	ABC, transporter
DMI67_04755	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
DMI67_04775	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DMI67_04780	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
DMI67_04790	ENOG4105C1J	atp-dependent rna helicase
DMI67_04805	ENOG4105EPC	oxidoreductase
DMI67_04825	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DMI67_04835	ENOG4105JAB	phenazine biosynthesis protein, phzf family
DMI67_04840	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
DMI67_04870	ENOG4108IAJ	Nad-dependent epimerase dehydratase
DMI67_04895	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DMI67_04945	ENOG4105E5D	amino acid
DMI67_04950	ENOG4105CSV	Glutaminase
DMI67_04965	ENOG4105BZG	amino acid carrier protein
DMI67_04975	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DMI67_04980	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DMI67_04985	ENOG4105C25	Primosomal protein n'
DMI67_04990	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DMI67_05010	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DMI67_05015	ENOG4107QJQ	Mate efflux family protein
DMI67_05060	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DMI67_05065	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
DMI67_05080	ENOG4105DIK	(ABC) transporter
DMI67_05085	ENOG4105CC5	ABC transporter
DMI67_05090	ENOG4108Z0C	Uvrb UvrC protein
DMI67_05095	ENOG41066A3	ATP guanido phosphotransferase
DMI67_05100	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DMI67_05110	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
DMI67_05115	ENOG4105ERH	Fumarylacetoacetate hydrolase
DMI67_05120	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DMI67_05135	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DMI67_05145	ENOG4105C31	Tryptophanyl-tRNA synthetase
DMI67_05155	ENOG4105D48	metallophosphoesterase
DMI67_05165	ENOG4105CUZ	uba thif-type nad fad binding protein
DMI67_05250	ENOG4107QMH	DNA methylase
DMI67_05255	ENOG4105D8D	Type III
DMI67_05325	ENOG4105D7K	pfkb domain protein
DMI67_05330	ENOG4105E09	nadh pyrophosphatase
DMI67_05340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DMI67_05355	ENOG4107WDG	serine threonine protein kinase
DMI67_05395	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
DMI67_05410	ENOG4105K78	MarR family Transcriptional regulator
DMI67_05420	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DMI67_05425	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DMI67_05435	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
DMI67_05440	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DMI67_05445	ENOG41083ND	50S ribosomal protein L33
DMI67_05450	ENOG4105SCY	DNAK suppressor
DMI67_05455	ENOG4105DKQ	ROK family
DMI67_05460	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DMI67_05470	ENOG4105M6F	mutator MutT protein
DMI67_05475	ENOG4105CW7	secretion protein, HlyD family
DMI67_05480	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DMI67_05485	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DMI67_05490	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
DMI67_05505	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
DMI67_05550	ENOG4108R96	Methyltransferase, YaeB family
DMI67_05555	ENOG4105CD3	dihydroorotase
DMI67_05560	ENOG4105CXT	aspartate transcarbamylase
DMI67_05565	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
DMI67_05580	ENOG4105DZ0	fad dependent oxidoreductase
DMI67_05585	ENOG4105DWY	Agmatine deiminase
DMI67_05595	ENOG4105DZP	Membrane-associated zinc metalloprotease
DMI67_05605	ENOG41061MV	Arylsulfatase
DMI67_05615	ENOG4105CE1	Ferrous iron transport protein b
DMI67_05650	ENOG4105DF5	DNA topoisomerase IV, subunit A
DMI67_05685	ENOG4105FA0	parb-like partition protein
DMI67_05715	ENOG4105DHU	Bile acid
DMI67_05720	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DMI67_05740	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DMI67_05745	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DMI67_05750	ENOG4107QSI	ABC, transporter
DMI67_05790	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DMI67_05795	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
DMI67_05810	ENOG4105BZ1	(ABC) transporter
DMI67_05815	ENOG4105BZ1	(ABC) transporter
DMI67_05830	ENOG4105DHJ	ABC, transporter
DMI67_05835	ENOG4107PE3	Mammalian cell entry related domain protein
DMI67_05860	ENOG4105CZX	twitching motility protein
DMI67_05865	ENOG4105CZX	twitching motility protein
DMI67_05870	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
DMI67_05885	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
DMI67_05890	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DMI67_05895	ENOG4107RJ1	sodium solute
DMI67_05925	ENOG4108JQC	penicillin-binding protein 1A
DMI67_05935	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DMI67_05940	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DMI67_05950	ENOG4105D60	lipoprotein releasing system transmembrane protein
DMI67_05950	ENOG4105D60	lipoprotein releasing system transmembrane protein
DMI67_05970	ENOG4107TV1	YD repeat protein
DMI67_05975	ENOG4105CNA	YD repeat protein
DMI67_06035	ENOG4107VAM	peptidase, m28
DMI67_06045	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DMI67_06050	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
DMI67_06065	ENOG4105C9B	Cysteine desulfurase
DMI67_06080	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
DMI67_06090	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DMI67_06100	ENOG4108ZVT	methylmalonyl-coA epimerase
DMI67_06105	ENOG4107QX3	carboxylase
DMI67_06115	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
DMI67_06120	ENOG4105D9Q	decarboxylase (Beta subunit)
DMI67_06125	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DMI67_06130	ENOG4105CYC	Transferase
DMI67_06145	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
DMI67_06150	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
DMI67_06155	ENOG4105CTQ	phosphohexokinase
DMI67_06165	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
DMI67_06170	ENOG4105C7K	acetolactate synthase
DMI67_06190	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
DMI67_06195	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
DMI67_06205	ENOG4105C8P	)-transporter
DMI67_06280	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DMI67_06285	ENOG4105CPQ	Dehydrogenase
DMI67_06295	ENOG4105EYW	Ion transport protein
DMI67_06300	ENOG41080E8	Transcriptional regulator, Spx MgsR family
DMI67_06305	ENOG4105CY0	Metallo-Beta-Lactamase
DMI67_06325	ENOG4105FE9	pseudouridine synthase
DMI67_06335	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DMI67_06340	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
DMI67_06350	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DMI67_06400	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DMI67_06405	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMI67_06410	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DMI67_06415	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DMI67_06455	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DMI67_06535	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
DMI67_06605	ENOG4105CDU	Replicative dna helicase
DMI67_06715	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
DMI67_06725	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
DMI67_06745	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DMI67_06750	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DMI67_06755	ENOG4105K5M	30s ribosomal protein S16
DMI67_06780	ENOG4105VIE	preprotein translocase, subunit YajC
DMI67_06785	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DMI67_06790	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DMI67_06800	ENOG4105K6T	rare lipoprotein A
DMI67_06805	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DMI67_06810	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DMI67_06865	ENOG4105CNT	hydrolase family 2
DMI67_06870	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DMI67_06880	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DMI67_06885	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DMI67_06890	ENOG41082SA	50s ribosomal protein l29
DMI67_06895	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DMI67_06900	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DMI67_06905	ENOG41080P9	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DMI67_06915	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DMI67_06920	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DMI67_06925	ENOG4108542	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DMI67_06930	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DMI67_06935	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DMI67_06940	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DMI67_06945	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DMI67_06950	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DMI67_06955	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DMI67_06965	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DMI67_06975	ENOG4105BZU	Histidine kinase
DMI67_06980	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DMI67_06995	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DMI67_07010	ENOG4108M8S	permease YjgP YjgQ family protein
DMI67_07015	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DMI67_07035	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DMI67_07045	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DMI67_07080	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
DMI67_07095	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DMI67_07105	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DMI67_07110	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DMI67_07130	ENOG4108IPT	Naphthoate synthase
DMI67_07175	ENOG4107T0D	ABC, transporter
DMI67_07190	ENOG4108IJ6	ABC transporter
DMI67_07200	ENOG4105EMU	Dehydrogenase
DMI67_07215	ENOG4108JUA	Transcriptional regulator
DMI67_07230	ENOG4105E2D	ec 3.2.1.52
DMI67_07245	ENOG4105CVK	Glutamate decarboxylase
DMI67_07255	ENOG4105C0B	DNA polymerase III (alpha subunit)
DMI67_07260	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
DMI67_07265	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DMI67_07285	ENOG4105C37	(CBS) domain
DMI67_07290	ENOG4105C37	(CBS) domain
DMI67_07295	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DMI67_07300	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DMI67_07330	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DMI67_07335	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DMI67_07355	ENOG4106855	Competence protein
DMI67_07370	ENOG4105E2D	ec 3.2.1.52
DMI67_07375	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DMI67_07395	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DMI67_07400	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DMI67_07410	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DMI67_07435	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
DMI67_07440	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
DMI67_07445	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DMI67_07450	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DMI67_07460	ENOG4108775	30S ribosomal protein S21
DMI67_07465	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DMI67_07475	ENOG4105C54	Major Facilitator superfamily
DMI67_07485	ENOG4105CX6	glutaminyL-tRNA synthetase
DMI67_07490	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
DMI67_07495	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DMI67_07500	ENOG410803B	Involved in the transcription termination process (By similarity)
DMI67_07505	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DMI67_07510	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DMI67_07515	ENOG4105CDU	Replicative dna helicase
DMI67_07530	ENOG4105CEV	competence damage-inducible protein
DMI67_07540	ENOG4108W0I	acetyltransferase
DMI67_07565	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DMI67_07570	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DMI67_07575	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DMI67_07580	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
DMI67_07595	ENOG4105C79	DNA protecting protein DprA
DMI67_07600	ENOG4105DZ1	carboxypeptidase
DMI67_07605	ENOG4105C3G	gtp-binding protein
DMI67_07620	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DMI67_07635	ENOG41061MV	Arylsulfatase
DMI67_07660	ENOG4105NQG	DoxX
DMI67_07665	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DMI67_07670	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
DMI67_07675	ENOG4105EMN	RNA polymerase sigma factor
DMI67_07695	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DMI67_07715	ENOG4105CSR	polyphosphate kinase 2
DMI67_07720	ENOG4107EDW	L-fucose operon activator
DMI67_07735	ENOG4105C3J	Cysteine desulfurase
DMI67_07745	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DMI67_07760	ENOG4106H78	methyltransferase
DMI67_07775	ENOG4105CSR	polyphosphate kinase 2
DMI67_07785	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
DMI67_07795	ENOG4107XM9	(LipO)protein
DMI67_07800	ENOG4105K8N	protein family UPF0079, ATPase
DMI67_07810	ENOG4105K46	50S ribosomal protein l27
DMI67_07815	ENOG4105G5W	regulator Fur family
DMI67_07820	ENOG4105C3K	feS assembly ATPase SufC
DMI67_07825	ENOG4105DIW	FeS assembly protein SUFB
DMI67_07830	ENOG4105JRK	feS assembly protein SufD
DMI67_07840	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DMI67_07845	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DMI67_07890	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DMI67_07910	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DMI67_07915	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DMI67_07920	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DMI67_07925	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DMI67_07930	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DMI67_07945	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
DMI67_07955	ENOG4105CJN	penicillin-binding protein
DMI67_07995	ENOG4105D06	uba thif-type nad fad binding protein
DMI67_08000	ENOG4105C2X	Arabinose 5-phosphate isomerase
DMI67_08020	ENOG4105D7W	serine acetyltransferase
DMI67_08030	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DMI67_08035	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DMI67_08040	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DMI67_08050	ENOG4107QPR	SAICAR synthetase
DMI67_08060	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
DMI67_08065	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
DMI67_08075	ENOG4105CN9	Peptidase m42 family protein
DMI67_08095	ENOG4105C03	ribonuclease
DMI67_08125	ENOG4109015	Biopolymer transport protein exbD tolR
DMI67_08140	ENOG4105CSM	endonuclease III
DMI67_08165	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DMI67_08170	ENOG41080R2	UPF0102 protein
DMI67_08180	ENOG4105C37	(CBS) domain
DMI67_08190	ENOG41082R9	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DMI67_08205	ENOG4105CDH	Citrulline--aspartate ligase
DMI67_08210	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DMI67_08220	ENOG4105CP7	Triose-phosphate isomerase
DMI67_08235	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DMI67_08255	ENOG41081UC	Inherit from COG: Competence protein
DMI67_08265	ENOG4105DXN	mazG family
DMI67_08290	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
DMI67_08300	ENOG4107RAN	Peptidase, M16
DMI67_08320	ENOG4105WPN	DNA integration recombination invertion protein
DMI67_08325	ENOG4107R11	Transcriptional regulator
DMI67_08330	ENOG4105SYT	Methylenetetrahydrofolate reductase
DMI67_08355	ENOG4105DGA	Diaminopimelate dehydrogenase
DMI67_08360	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
DMI67_08380	ENOG4105C7B	Threonine dehydratase
DMI67_08385	ENOG4108Z03	MAF-like protein
DMI67_08390	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DMI67_08410	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
DMI67_08420	ENOG4105CAT	Cytidine monophosphate kinase
DMI67_08430	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DMI67_08440	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DMI67_08455	ENOG4105CGK	Exodeoxyribonuclease III
DMI67_08460	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DMI67_08475	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DMI67_08480	ENOG4107QRG	dna polymerase iii
DMI67_08510	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
DMI67_08590	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DMI67_08595	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DMI67_08600	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
DMI67_08605	ENOG4105K64	Glycosyl transferase, family 2
DMI67_08610	ENOG4105K64	Glycosyl transferase, family 2
DMI67_08635	ENOG4107TAE	Glycosyl transferase (Group 1
DMI67_08655	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DMI67_08665	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DMI67_08670	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
DMI67_08680	ENOG4105EN6	Membrane
DMI67_08685	ENOG4105CY0	Metallo-Beta-Lactamase
DMI67_08690	ENOG4108V6E	Cell division protein mraZ
DMI67_08695	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DMI67_08705	ENOG4105CJN	penicillin-binding protein
DMI67_08710	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DMI67_08715	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
DMI67_08720	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DMI67_08725	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DMI67_08735	ENOG4105CNI	cell division protein FtsW
DMI67_08740	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DMI67_08745	ENOG4105DFU	Cell wall formation (By similarity)
DMI67_08750	ENOG4105CPF	Cell wall formation (By similarity)
DMI67_08760	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
DMI67_08765	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
DMI67_08770	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DMI67_08775	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DMI67_08780	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DMI67_08790	ENOG4105C0H	protease
DMI67_08800	ENOG4105D49	3-dehydroquinate synthase
DMI67_08810	ENOG4108JQ7	(ABC) transporter
DMI67_08820	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DMI67_08825	ENOG4105CE9	30S ribosomal protein S2
DMI67_08835	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
DMI67_08850	ENOG4108IUZ	ABC transporter
DMI67_08860	ENOG4105DFU	Cell wall formation (By similarity)
DMI67_08865	ENOG4105UYK	outer membrane protein a
DMI67_08890	ENOG4105C5S	asparaginyl-tRNA synthetase
DMI67_08900	ENOG4105K63	Thioredoxin
DMI67_08950	ENOG4105HMI	Membrane
DMI67_08955	ENOG4107STF	Involved in phosphonate degradation (By similarity)
DMI67_08980	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DMI67_08985	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DMI67_08990	ENOG4105CDY	transcriptional regulatory protein
DMI67_09000	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DMI67_09010	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
DMI67_09015	ENOG4105DI5	UPF0365 protein
DMI67_09025	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DMI67_09030	ENOG4107RY6	amino acid
DMI67_09040	ENOG4105DSF	transport protein
DMI67_09045	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DMI67_09050	ENOG4107RCW	fructose-bisphosphate aldolase
DMI67_09055	ENOG4105CI3	gtp-binding protein typa
DMI67_09060	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DMI67_09090	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DMI67_09140	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DMI67_09145	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DMI67_09170	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DMI67_09195	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DMI67_09200	ENOG4105X0D	Fimbrial protein
DMI67_09210	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
DMI67_09220	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DMI67_09235	ENOG4105DIN	metallophosphoesterase
DMI67_09255	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
DMI67_09260	ENOG4105K64	Glycosyl transferase, family 2
DMI67_09280	ENOG4105EXC	Acyl-transferase
DMI67_09300	ENOG4107QWE	)-transporter
DMI67_09340	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DMI67_09345	ENOG4105C5I	Dehydrogenase
DMI67_09355	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DMI67_09360	ENOG4105NAU	thioesterase Superfamily protein
DMI67_09370	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DMI67_09380	ENOG4105KK6	nuclease
DMI67_09395	ENOG4105GTN	ParB Domain Protein Nuclease
DMI67_09400	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
DMI67_09415	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DMI67_09430	ENOG4105C0P	Mg chelatase subunit ChlI
DMI67_09450	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
DMI67_09465	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DMI67_09470	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
DMI67_09480	ENOG4105CRK	lysyL-tRNA synthetase
DMI67_09505	ENOG4105KVH	Transcriptional regulator
DMI67_09515	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DMI67_09535	ENOG4105CQ7	ATP-dependent helicase
DMI67_09540	ENOG4108ZP8	Acetolactate synthase small subunit
DMI67_09545	ENOG4105C0H	protease
DMI67_09555	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
DMI67_09560	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DMI67_09565	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DMI67_09595	ENOG4105F8V	Hydrolase, tatD family
DMI67_09605	ENOG4105CNT	hydrolase family 2
DMI67_09620	ENOG4105C08	Histidine kinase
DMI67_09625	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
DMI67_09635	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DMI67_09640	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DMI67_09645	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
DMI67_09665	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DMI67_09715	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DMI67_09725	ENOG4105CHH	sulfate transporter
DMI67_09730	ENOG4105CH7	arginosuccinase
DMI67_09745	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DMI67_09750	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
DMI67_09760	ENOG4105EQI	Metal Dependent Phosphohydrolase
DMI67_09770	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DMI67_09775	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DMI67_09820	ENOG4105DME	alpha-galactosidase
DMI67_09840	ENOG4105D0C	transport protein
DMI67_09855	ENOG4105C8P	)-transporter
DMI67_09890	ENOG4108RAC	Rubrerythrin
DMI67_09900	ENOG4105CN9	Peptidase m42 family protein
DMI67_09905	ENOG4105E2D	ec 3.2.1.52
DMI67_09915	ENOG4105G6Z	alkaline phosphatase
DMI67_09920	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
DMI67_09925	ENOG4105C8Y	Acetylornithine aminotransferase
DMI67_09935	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DMI67_09945	ENOG4105C59	p-type ATPase
DMI67_09950	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DMI67_09955	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DMI67_09960	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
DMI67_09995	ENOG4105CPP	Dehydrogenase, E1 component
DMI67_10000	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DMI67_10015	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
DMI67_10020	ENOG4105BZS	acriflavin resistance protein
DMI67_10055	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DMI67_10075	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
DMI67_10080	ENOG4107QM5	aconitate hydratase
DMI67_10110	ENOG4105E0Y	RtcB Protein
DMI67_10120	ENOG4105CZM	Major Facilitator
DMI67_10130	ENOG4108WBT	adenosyltransferase
DMI67_10140	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DMI67_10165	ENOG4105CFP	Peptidase U32
DMI67_10170	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DMI67_10185	ENOG410823G	oxidoreductase
DMI67_10190	ENOG4105C0D	helicase
DMI67_10195	ENOG4105CGH	5'-nucleotidase
DMI67_10200	ENOG4105K6T	rare lipoprotein A
DMI67_10205	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DMI67_10210	ENOG41082A0	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DMI67_10225	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DMI67_10230	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
DMI67_10235	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DMI67_10240	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DMI67_10245	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DMI67_10250	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DMI67_10255	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DMI67_10270	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
DMI67_10285	ENOG4107QRS	glycosyltransferase group 2 family protein
DMI67_10295	ENOG4105K64	Glycosyl transferase, family 2
DMI67_10310	ENOG4105K64	Glycosyl transferase, family 2
DMI67_10315	ENOG4108Z0Z	intracellular protease Pfpi family
DMI67_10320	ENOG4105C7S	Dehydrogenase
DMI67_10325	ENOG4105CE4	GlcNAc 6-P deacetylase
DMI67_10330	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
DMI67_10350	ENOG4105ENH	Sulfatase
DMI67_10355	ENOG41084NN	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DMI67_10360	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DMI67_10365	ENOG4105CHV	Transcription elongation factor NusA
DMI67_10370	ENOG4105CGK	Exodeoxyribonuclease III
DMI67_10375	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DMI67_10395	ENOG4105IDI	abc transporter atp-binding protein
DMI67_10415	ENOG4105VFU	Rna-binding protein
DMI67_10420	ENOG4105D3Q	Sugar transferase
DMI67_10440	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DMI67_10450	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
DMI67_10455	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DMI67_10470	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
DMI67_10480	ENOG4105E33	succinate dehydrogenase
DMI67_10535	ENOG4105CHR	reductase
DMI67_10550	ENOG4105C5H	ABC transporter
DMI67_10560	ENOG4105MS2	ribosomal subunit Interface protein
DMI67_10575	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
DMI67_10585	ENOG4105ENX	hydrolase
DMI67_10595	ENOG4105CPC	Aldo Keto reductase
DMI67_10615	ENOG4105DY9	regulatoR
DMI67_10650	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DMI67_10655	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
DMI67_10685	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
DMI67_10690	ENOG4105C5H	ABC transporter
DMI67_10760	ENOG4105C8N	cysteinyl-tRNA synthetase
DMI67_10765	ENOG4105E2D	ec 3.2.1.52
DMI67_10770	ENOG4105CBG	Sulfatase
DMI67_10785	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DMI67_10810	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DMI67_10815	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DMI67_10820	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DMI67_10825	ENOG4107Z3D	50S ribosomal protein l10
DMI67_10830	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DMI67_10835	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DMI67_10840	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DMI67_10855	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DMI67_10865	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DMI67_10875	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DMI67_10880	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DMI67_10885	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMI67_10895	ENOG4105SYT	Methylenetetrahydrofolate reductase
DMI67_10915	ENOG4108IJF	Heavy metal efflux pump, CzcA
DMI67_10960	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
DMI67_10965	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DMI67_10970	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
DMI67_10995	ENOG4105CBG	Sulfatase
DMI67_11000	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DMI67_11010	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
DMI67_11020	ENOG4108IYU	L-aspartate oxidase
DMI67_11025	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DMI67_11090	ENOG4105CA0	peroxidase
DMI67_11095	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DMI67_11100	ENOG4108Z6B	deaminase
DMI67_11105	ENOG4105DKQ	ROK family
DMI67_11110	ENOG4105C59	p-type ATPase
DMI67_11115	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DMI67_11120	ENOG4105GVR	general secretion pathway protein D
DMI67_11150	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DMI67_11160	ENOG4107RAQ	aminopeptidase
DMI67_11165	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DMI67_11185	ENOG4105BZU	Histidine kinase
DMI67_11190	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DMI67_11195	ENOG4105C01	Dihydroxy-acid dehydratase
DMI67_11280	ENOG4105E0M	Sulfatase
DMI67_11315	ENOG4105CMR	udp-glucose 4-epimerase
DMI67_11320	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DMI67_11345	ENOG4107QI1	Mate efflux family protein
DMI67_11490	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DMI67_11495	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
DMI67_11500	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
DMI67_11505	ENOG4105C08	Histidine kinase
DMI67_11515	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
DMI67_11525	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DMI67_11540	ENOG4105CPC	Aldo Keto reductase
DMI67_11545	ENOG4105V75	Transcriptional regulator
DMI67_11595	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DMI67_11620	ENOG4105ECP	epimerase
DMI67_11635	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DMI67_11640	ENOG4105DKW	ABC transporter
DMI67_11645	ENOG4105C6F	GntR Family Transcriptional Regulator
DMI67_11660	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
DMI67_11670	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DMI67_11680	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
DMI67_11685	ENOG4105CJ2	(LipO)protein
DMI67_11700	ENOG41085AM	50S ribosomal protein L28
DMI67_11715	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DMI67_11720	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
DMI67_11730	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
DMI67_11735	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DMI67_11745	ENOG4105DVT	helicase
DMI67_11750	ENOG4108JJB	ABC transporter
DMI67_11775	ENOG4105CAS	nag kinase
DMI67_11780	ENOG4107QUT	magnesium and cobalt transport protein CorA
DMI67_11785	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DMI67_11790	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DMI67_11795	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
DMI67_11800	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DMI67_11810	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
DMI67_11815	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
DMI67_11830	ENOG4107SFQ	iron-sulfur binding
DMI67_11850	ENOG4105D49	3-dehydroquinate synthase
DMI67_11905	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
DMI67_11925	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
DMI67_11930	ENOG4105C6E	dna polymerase iii
DMI67_11950	ENOG4105W5Q	DNA repair protein (RadC
DMI67_11955	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DMI67_11960	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DMI67_11965	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DMI67_11970	ENOG4108UJD	30S ribosomal protein S9
DMI67_11975	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
DMI67_11980	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DMI67_11990	ENOG4109015	Biopolymer transport protein exbD tolR
DMI67_12000	ENOG4108JQC	penicillin-binding protein 1A
DMI67_12005	ENOG4105ECY	inositol monophosphatase
DMI67_12010	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DMI67_12020	ENOG4105DG6	mannose-6-phosphate isomerase
DMI67_12030	ENOG4105DFD	Na H antiporter
DMI67_12035	ENOG4105C30	Nad-dependent epimerase dehydratase
DMI67_12040	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
DMI67_12045	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DMI67_12050	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DMI67_12060	ENOG4105CBC	glutamate synthase
DMI67_12065	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DMI67_12070	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DMI67_12110	ENOG4105DSB	aldose 1-epimerase
DMI67_12120	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DMI67_12130	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DMI67_12150	ENOG4105EJQ	L-serine dehydratase
DMI67_12155	ENOG4105C3M	thioredoxin reductase
DMI67_12210	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DMI67_12215	ENOG4105DIN	metallophosphoesterase
DMI67_12230	ENOG4108V1T	peptidylprolyl cis-trans isomerase