locus-tag	class	description
AKMU_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKMU_00020	COG1131	(ABC) transporter
AKMU_00060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AKMU_00070	COG0564	pseudouridine synthase activity
AKMU_00100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKMU_00110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKMU_00120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AKMU_00180	COG0673	inositol 2-dehydrogenase activity
AKMU_00210	COG2814	Major facilitator Superfamily
AKMU_00220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AKMU_00250	COG1971	Probably functions as a manganese efflux pump
AKMU_00300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKMU_00350	COG0442	prolyl-tRNA aminoacylation
AKMU_00370	COG0531	amino acid
AKMU_00380	COG2066	Belongs to the glutaminase family
AKMU_00400	COG1115	amino acid carrier protein
AKMU_00410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKMU_00420	COG2890	protein-(glutamine-N5) methyltransferase activity
AKMU_00430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKMU_00440	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AKMU_00470	COG2226	methyltransferase
AKMU_00480	COG0534	Mate efflux family protein
AKMU_00550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKMU_00560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AKMU_00570	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_00600	COG1121	(ABC) transporter
AKMU_00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKMU_00620	COG3880	PFAM UvrB UvrC protein
AKMU_00630	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AKMU_00640	COG0542	response to heat
AKMU_00670	COG0179	Fumarylacetoacetate (FAA) hydrolase
AKMU_00680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKMU_00710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AKMU_00710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AKMU_00740	COG0180	Tryptophanyl-tRNA synthetase
AKMU_00760	COG1692	metallophosphoesterase
AKMU_00770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AKMU_00790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKMU_00800	COG2816	NAD+ diphosphatase activity
AKMU_00810	COG0156	8-amino-7-oxononanoate synthase activity
AKMU_00830	COG1192	Involved in chromosome partitioning
AKMU_00840	COG3266	domain, Protein
AKMU_00840	COG0515	serine threonine protein kinase
AKMU_00860	COG4974	Belongs to the 'phage' integrase family
AKMU_00900	COG0326	Molecular chaperone. Has ATPase activity
AKMU_00960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AKMU_00980	COG3189	MarR family transcriptional regulator
AKMU_00990	COG0181	hydroxymethylbilane synthase activity
AKMU_01000	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AKMU_01020	COG1469	GTP cyclohydrolase I activity
AKMU_01030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AKMU_01040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AKMU_01050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKMU_01060	COG1940	carbohydrate kinase activity
AKMU_01090	COG0494	nUDIX hydrolase
AKMU_01110	COG1566	PFAM secretion protein HlyD family protein
AKMU_01120	COG0577	efflux transmembrane transporter activity
AKMU_01120	COG1136	(ABC) transporter
AKMU_01130	COG1136	(ABC) transporter
AKMU_01130	COG0577	efflux transmembrane transporter activity
AKMU_01170	COG1720	tRNA m6t6A37 methyltransferase activity
AKMU_01180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AKMU_01190	COG0540	Belongs to the ATCase OTCase family
AKMU_01200	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AKMU_01230	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AKMU_01240	COG2957	Belongs to the agmatine deiminase family
AKMU_01260	COG0750	zinc metalloprotease
AKMU_01280	COG3119	arylsulfatase activity
AKMU_01300	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AKMU_01300	COG1918	ferrous iron import across plasma membrane
AKMU_01390	COG1475	DNA binding
AKMU_01460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKMU_01490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKMU_01500	COG0601	transmembrane transport
AKMU_01620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKMU_01630	COG1132	(ABC) transporter
AKMU_01640	COG1132	(ABC) transporter
AKMU_01680	COG1127	ABC transporter
AKMU_01690	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AKMU_01750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKMU_01770	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AKMU_01780	COG0504	CTP synthase activity
AKMU_01790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKMU_01840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKMU_01860	COG1322	Protein conserved in bacteria
AKMU_01870	COG0546	phosphoglycolate phosphatase activity
AKMU_01880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKMU_01900	COG4591	ABC-type transport system involved in lipoprotein release permease component
AKMU_01900	COG4591	ABC-type transport system involved in lipoprotein release permease component
AKMU_01960	COG0657	acetylesterase activity
AKMU_01960	COG2755	lipolytic protein G-D-S-L family
AKMU_01970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AKMU_02010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKMU_02020	COG2267	carboxylic ester hydrolase activity
AKMU_02050	COG0335	large ribosomal subunit rRNA binding
AKMU_02070	COG0346	lactoylglutathione lyase activity
AKMU_02100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AKMU_02110	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AKMU_02120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AKMU_02120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AKMU_02130	COG0427	acetyl-CoA hydrolase
AKMU_02150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AKMU_02170	COG0205	6-phosphofructokinase activity
AKMU_02190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKMU_02200	COG0028	Belongs to the TPP enzyme family
AKMU_02240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AKMU_02270	COG0471	metal ion transport
AKMU_02290	COG0351	phosphomethylpyrimidine kinase
AKMU_02360	COG1028	Short-chain dehydrogenase reductase Sdr
AKMU_02380	COG0242	peptide deformylase activity
AKMU_02390	COG1063	alcohol dehydrogenase
AKMU_02410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AKMU_02420	COG1393	Belongs to the ArsC family
AKMU_02430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AKMU_02460	COG1187	pseudouridine synthase activity
AKMU_02480	COG0336	Belongs to the RNA methyltransferase TrmD family
AKMU_02490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKMU_02510	COG0539	negative regulation of cytoplasmic translation
AKMU_02600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AKMU_02610	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AKMU_02620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AKMU_02630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKMU_02640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKMU_02790	COG3015	lipoprotein NlpE involved in copper resistance
AKMU_02930	COG0305	Participates in initiation and elongation during chromosome replication
AKMU_03150	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AKMU_03150	COG0662	Cupin 2, conserved barrel domain protein
AKMU_03170	COG0416	fatty acid biosynthetic process
AKMU_03180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AKMU_03200	COG0537	adenosine 5'-monophosphoramidase activity
AKMU_03210	COG0009	L-threonylcarbamoyladenylate synthase
AKMU_03220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AKMU_03230	COG0228	four-way junction DNA binding
AKMU_03270	COG1862	Preprotein translocase
AKMU_03280	COG0343	queuine tRNA-ribosyltransferase activity
AKMU_03290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AKMU_03310	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKMU_03320	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKMU_03330	COG0776	regulation of translation
AKMU_03390	COG0811	peptide transport
AKMU_03420	COG3250	beta-galactosidase activity
AKMU_03430	COG0525	valine-tRNA ligase activity
AKMU_03450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKMU_03460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKMU_03470	COG0255	Belongs to the universal ribosomal protein uL29 family
AKMU_03480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AKMU_03490	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKMU_03500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKMU_03520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKMU_03530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKMU_03540	COG0089	rRNA binding
AKMU_03550	COG0088	Forms part of the polypeptide exit tunnel
AKMU_03560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKMU_03570	COG0051	transcription antitermination factor activity, RNA binding
AKMU_03580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKMU_03590	COG0049	tRNA binding
AKMU_03600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKMU_03610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKMU_03630	COG3852	Histidine kinase
AKMU_03640	COG2204	response regulator
AKMU_03660	COG1722	exodeoxyribonuclease VII activity
AKMU_03670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKMU_03700	COG0795	lipopolysaccharide-transporting ATPase activity
AKMU_03710	COG1160	GTP binding
AKMU_03720	COG0444	Belongs to the ABC transporter superfamily
AKMU_03760	COG1136	(ABC) transporter
AKMU_03760	COG0577	efflux transmembrane transporter activity
AKMU_03780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AKMU_03870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AKMU_03880	COG0799	negative regulation of ribosome biogenesis
AKMU_03890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AKMU_03990	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AKMU_04020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AKMU_04040	COG0300	oxidoreductase activity
AKMU_04080	COG0038	chloride channel
AKMU_04100	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_04130	COG0076	glutamate decarboxylase activity
AKMU_04160	COG0167	dihydroorotate dehydrogenase activity
AKMU_04170	COG0352	thiamine-phosphate diphosphorylase activity
AKMU_04210	COG1253	flavin adenine dinucleotide binding
AKMU_04220	COG1253	flavin adenine dinucleotide binding
AKMU_04230	COG1185	polyribonucleotide nucleotidyltransferase activity
AKMU_04240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKMU_04250	COG0110	maltose O-acetyltransferase activity
AKMU_04300	COG0101	tRNA pseudouridine synthase activity
AKMU_04310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AKMU_04350	COG4968	Prepilin-type N-terminal cleavage methylation domain
AKMU_04380	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_04390	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AKMU_04430	COG1136	(ABC) transporter
AKMU_04440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AKMU_04460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKMU_04510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_04520	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AKMU_04530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AKMU_04550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AKMU_04560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AKMU_04580	COG2814	Major facilitator Superfamily
AKMU_04600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKMU_04610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AKMU_04610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AKMU_04620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AKMU_04630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKMU_04640	COG0552	protein localization to endoplasmic reticulum
AKMU_04650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AKMU_04730	COG1058	Belongs to the CinA family
AKMU_04730	COG1546	Belongs to the CinA family
AKMU_04750	COG0456	acetyltransferase
AKMU_04800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKMU_04810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKMU_04820	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKMU_04830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AKMU_04860	COG0758	DNA mediated transformation
AKMU_04870	COG1686	Belongs to the peptidase S11 family
AKMU_04880	COG0012	GTP binding
AKMU_04910	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKMU_04910	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AKMU_04940	COG3119	arylsulfatase activity
AKMU_04990	COG2259	Doxx family
AKMU_05000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AKMU_05060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKMU_05100	COG2326	polyphosphate kinase activity
AKMU_05110	COG1349	DNA-binding transcription factor activity
AKMU_05140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKMU_05150	COG1162	GTPase activity
AKMU_05180	COG0742	ribosomal rna small subunit methyltransferase
AKMU_05210	COG2326	polyphosphate kinase activity
AKMU_05230	COG5434	Belongs to the glycosyl hydrolase 28 family
AKMU_05250	COG1073	alpha beta
AKMU_05260	COG0802	atpase or kinase
AKMU_05280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AKMU_05290	COG0735	belongs to the Fur family
AKMU_05300	COG0396	ATPase activity
AKMU_05310	COG0719	Fe-S assembly protein
AKMU_05320	COG0719	Fe-S assembly protein
AKMU_05350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AKMU_05430	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AKMU_05470	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AKMU_05480	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKMU_05490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKMU_05500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKMU_05510	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKMU_05520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKMU_05540	COG0356	it plays a direct role in the translocation of protons across the membrane
AKMU_05680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AKMU_05740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AKMU_05750	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AKMU_05760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AKMU_05780	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AKMU_05800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AKMU_05810	COG0047	phosphoribosylformylglycinamidine synthase activity
AKMU_05830	COG1363	Peptidase, m42
AKMU_05860	COG1077	Cell shape determining protein MreB Mrl
AKMU_05870	COG1530	ribonuclease E activity
AKMU_05910	COG0848	biopolymer transport protein
AKMU_05940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKMU_05970	COG0134	indole-3-glycerol-phosphate synthase activity
AKMU_05980	COG0792	nuclease activity
AKMU_06000	COG1253	flavin adenine dinucleotide binding
AKMU_06020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKMU_06030	COG0137	argininosuccinate synthase activity
AKMU_06060	COG0149	triose-phosphate isomerase activity
AKMU_06130	COG1040	competence protein
AKMU_06150	COG3956	TIGRFAM MazG family protein
AKMU_06190	COG1663	tetraacyldisaccharide 4'-kinase activity
AKMU_06200	COG0612	Peptidase, M16
AKMU_06250	COG0673	inositol 2-dehydrogenase activity
AKMU_06260	COG3034	peptidoglycan biosynthetic process
AKMU_06290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AKMU_06300	COG0424	maF-like protein
AKMU_06310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKMU_06370	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AKMU_06390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKMU_06410	COG0571	ribonuclease III activity
AKMU_06430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AKMU_06560	COG0708	Exodeoxyribonuclease III
AKMU_06570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AKMU_06600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AKMU_06640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AKMU_06670	COG2226	methyltransferase
AKMU_06690	COG2076	Multidrug Resistance protein
AKMU_06780	COG2255	four-way junction helicase activity
AKMU_06790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AKMU_06800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AKMU_06810	COG1215	transferase activity, transferring glycosyl groups
AKMU_06830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AKMU_06850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AKMU_06880	COG0438	transferase activity, transferring glycosyl groups
AKMU_06930	COG1216	Glycosyl transferase, family 2
AKMU_06930	COG0463	Glycosyl transferase, family 2
AKMU_06990	COG1053	succinate dehydrogenase
AKMU_07000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AKMU_07060	COG3209	COG3209 Rhs family protein
AKMU_07090	COG1490	D-aminoacyl-tRNA deacylase activity
AKMU_07120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKMU_07130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AKMU_07140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AKMU_07150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKMU_07190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AKMU_07200	COG0724	RNA recognition motif
AKMU_07240	COG1716	ATPase activity
AKMU_07240	COG1131	(ABC) transporter
AKMU_07240	COG0842	Transport permease protein
AKMU_07260	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKMU_07270	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AKMU_07280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AKMU_07290	COG0708	Exodeoxyribonuclease III
AKMU_07300	COG0195	Participates in both transcription termination and antitermination
AKMU_07310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKMU_07320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKMU_07330	COG3119	arylsulfatase activity
AKMU_07380	COG1966	Carbon starvation protein
AKMU_07400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKMU_07410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AKMU_07420	COG0508	dehydrogenase complex catalyzes the overall conversion of
AKMU_07430	COG0693	protein deglycase activity
AKMU_07440	COG1216	Glycosyl transferase, family 2
AKMU_07460	COG1216	Glycosyl transferase, family 2
AKMU_07480	COG1216	Glycosyl transferase, family 2
AKMU_07510	COG1442	glycosyl transferase family 8
AKMU_07520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AKMU_07550	COG0024	Methionine aminopeptidase
AKMU_07560	COG0563	adenylate kinase activity
AKMU_07570	COG0201	protein transport
AKMU_07590	COG0200	Binds to the 23S rRNA
AKMU_07600	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKMU_07610	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKMU_07620	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKMU_07630	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKMU_07650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKMU_07660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKMU_07670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKMU_07680	COG0737	Belongs to the 5'-nucleotidase family
AKMU_07690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AKMU_07700	COG0673	inositol 2-dehydrogenase activity
AKMU_07720	COG0285	dihydrofolate synthase activity
AKMU_07730	COG0826	peptidase U32
AKMU_07750	COG0557	exoribonuclease II activity
AKMU_07770	COG2096	Adenosyltransferase
AKMU_07790	COG2814	Major facilitator Superfamily
AKMU_07810	COG1690	Belongs to the RtcB family
AKMU_07860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AKMU_07870	COG5632	N-Acetylmuramoyl-L-alanine amidase
AKMU_07870	COG3409	Peptidoglycan-binding domain 1 protein
AKMU_07950	COG2738	Putative neutral zinc metallopeptidase
AKMU_07970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKMU_07980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKMU_07990	COG0789	Transcriptional regulator
AKMU_08000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKMU_08010	COG0022	dehydrogenase e1 component
AKMU_08020	COG0508	dehydrogenase complex catalyzes the overall conversion of
AKMU_08080	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AKMU_08090	COG0321	lipoyl(octanoyl) transferase activity
AKMU_08090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AKMU_08100	COG0497	DNA recombination
AKMU_08110	COG2217	Heavy metal translocating P-type atpase
AKMU_08130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKMU_08150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AKMU_08160	COG1970	mechanosensitive ion channel activity
AKMU_08170	COG1785	Belongs to the alkaline phosphatase family
AKMU_08190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_08200	COG1363	Peptidase, m42
AKMU_08220	COG1592	Rubrerythrin
AKMU_08230	COG2194	sulfuric ester hydrolase activity
AKMU_08280	COG0471	metal ion transport
AKMU_08310	COG0490	domain, Protein
AKMU_08310	COG2985	domain, Protein
AKMU_08370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKMU_08380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AKMU_08400	COG3481	metal-dependent phosphohydrolase, HD sub domain
AKMU_08420	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AKMU_08430	COG0148	phosphopyruvate hydratase activity
AKMU_08460	COG0165	Argininosuccinate lyase
AKMU_08470	COG0659	secondary active sulfate transmembrane transporter activity
AKMU_08490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKMU_08530	COG0542	response to heat
AKMU_08580	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AKMU_08600	COG0745	RESPONSE REGULATOR receiver
AKMU_08610	COG2205	protein histidine kinase activity
AKMU_08640	COG3250	beta-galactosidase activity
AKMU_08660	COG0084	hydrolase, TatD family'
AKMU_08670	COG1388	LysM domain
AKMU_08670	COG0791	NLP P60 protein
AKMU_08720	COG0592	DNA-directed DNA polymerase activity
AKMU_08740	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKMU_08750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKMU_08750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKMU_08760	COG0445	tRNA wobble uridine modification
AKMU_08780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKMU_08790	COG0440	acetolactate synthase activity
AKMU_08800	COG1643	Atp-dependent helicase
AKMU_08820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AKMU_08840	COG0107	imidazoleglycerol-phosphate synthase activity
AKMU_08860	COG1733	regulation of RNA biosynthetic process
AKMU_08900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AKMU_08920	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AKMU_08930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AKMU_08960	COG0535	radical SAM domain protein
AKMU_09030	COG0473	3-isopropylmalate dehydrogenase activity
AKMU_09050	COG3969	phosphoadenosine phosphosulfate
AKMU_09060	COG1475	DNA binding
AKMU_09080	COG1525	nuclease
AKMU_09100	COG1028	Short-chain dehydrogenase reductase Sdr
AKMU_09120	COG1607	acyl-coa hydrolase
AKMU_09130	COG0477	Major facilitator Superfamily
AKMU_09150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKMU_09160	COG0588	phosphoglycerate mutase activity
AKMU_09220	COG0471	metal ion transport
AKMU_09220	COG0490	domain, Protein
AKMU_09250	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AKMU_09250	COG2755	lipolytic protein G-D-S-L family
AKMU_09290	COG1216	Glycosyl transferase, family 2
AKMU_09300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKMU_09320	COG1442	glycosyl transferase family 8
AKMU_09320	COG1216	Glycosyl transferase, family 2
AKMU_09340	COG1408	metallophosphoesterase
AKMU_09370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKMU_09380	COG0196	riboflavin kinase activity
AKMU_09390	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AKMU_09420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKMU_09460	COG0546	phosphoglycolate phosphatase activity
AKMU_09480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AKMU_09480	COG0519	Catalyzes the synthesis of GMP from XMP
AKMU_09490	COG0516	GMP reductase activity
AKMU_09490	COG0517	IMP dehydrogenase activity
AKMU_09500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKMU_09560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKMU_09620	COG0191	fructose-bisphosphate aldolase activity
AKMU_09630	COG0019	diaminopimelate decarboxylase activity
AKMU_09640	COG0628	permease
AKMU_09660	COG0531	amino acid
AKMU_09670	COG2022	thiamine diphosphate biosynthetic process
AKMU_09690	COG4864	UPF0365 protein
AKMU_09700	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AKMU_09720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AKMU_09720	COG4651	solute:proton antiporter activity
AKMU_09730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AKMU_09740	COG0217	transcriptional regulatory protein
AKMU_09750	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AKMU_09760	COG0602	queuosine metabolic process
AKMU_09780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKMU_09800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AKMU_09810	COG2855	membrane
AKMU_09820	COG0583	DNA-binding transcription factor activity
AKMU_09910	COG3118	belongs to the thioredoxin family
AKMU_09930	COG0017	Asparaginyl-tRNA synthetase
AKMU_09990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKMU_10010	COG1137	ATPase activity
AKMU_10040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AKMU_10070	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKMU_10080	COG4608	Belongs to the ABC transporter superfamily
AKMU_10090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AKMU_10110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKMU_10130	COG0066	3-isopropylmalate dehydratase activity
AKMU_10140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKMU_10150	COG0321	lipoyl(octanoyl) transferase activity
AKMU_10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKMU_10170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AKMU_10190	COG1181	Belongs to the D-alanine--D-alanine ligase family
AKMU_10200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKMU_10210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AKMU_10220	COG0772	Belongs to the SEDS family
AKMU_10240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKMU_10250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKMU_10260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AKMU_10270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AKMU_10280	COG0768	penicillin binding
AKMU_10300	COG0275	rRNA processing
AKMU_10310	COG2001	Belongs to the MraZ family
AKMU_10320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AKMU_10330	COG2860	membrane
AKMU_10350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AKMU_10360	COG0482	sulfurtransferase activity
AKMU_10410	COG1028	Short-chain dehydrogenase reductase Sdr
AKMU_10430	COG0488	(ABC) transporter
AKMU_10460	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKMU_10470	COG1253	flavin adenine dinucleotide binding
AKMU_10480	COG1028	Short-chain dehydrogenase reductase Sdr
AKMU_10500	COG1073	alpha beta
AKMU_10520	COG0667	Aldo Keto reductase
AKMU_10630	COG2267	carboxylic ester hydrolase activity
AKMU_10640	COG2095	MarC family integral membrane protein
AKMU_10720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKMU_10730	COG0488	(ABC) transporter
AKMU_10750	COG0697	spore germination
AKMU_10770	COG0215	cysteine-tRNA ligase activity
AKMU_10790	COG3119	arylsulfatase activity
AKMU_10820	COG0481	GTPase activity
AKMU_10850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKMU_10860	COG0085	RNA polymerase activity
AKMU_10870	COG0222	ribosome binding
AKMU_10880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKMU_10890	COG0081	regulation of translation
AKMU_10900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKMU_10910	COG0250	Participates in transcription elongation, termination and antitermination
AKMU_10930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKMU_10940	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKMU_10960	COG0740	serine-type endopeptidase activity
AKMU_10970	COG0544	peptidyl-prolyl cis-trans isomerase activity
AKMU_11000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AKMU_11040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKMU_11130	COG2226	methyltransferase
AKMU_11140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKMU_11150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AKMU_11180	COG1902	pentaerythritol trinitrate reductase activity
AKMU_11180	COG0446	pyridine nucleotide-disulphide oxidoreductase
AKMU_11200	COG3119	arylsulfatase activity
AKMU_11210	COG0514	ATP-dependent DNA helicase (RecQ)
AKMU_11250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AKMU_11260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKMU_11370	COG1858	cytochrome C peroxidase
AKMU_11380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AKMU_11390	COG0590	tRNA wobble adenosine to inosine editing
AKMU_11400	COG1940	carbohydrate kinase activity
AKMU_11410	COG2217	Heavy metal translocating P-type atpase
AKMU_11420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AKMU_11430	COG0237	dephospho-CoA kinase activity
AKMU_11490	COG1363	Peptidase, m42
AKMU_11500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKMU_11520	COG0006	proline dipeptidase activity
AKMU_11530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AKMU_11570	COG5002	protein histidine kinase activity
AKMU_11580	COG0745	RESPONSE REGULATOR receiver
AKMU_11590	COG0129	dihydroxy-acid dehydratase activity
AKMU_11640	COG1368	sulfuric ester hydrolase activity
AKMU_11710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AKMU_11720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AKMU_11760	COG0534	Mate efflux family protein
AKMU_11770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AKMU_11790	COG1876	peptidase activity
AKMU_12070	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AKMU_12080	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AKMU_12090	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AKMU_12100	COG2205	protein histidine kinase activity
AKMU_12130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AKMU_12180	COG0789	Transcriptional regulator
AKMU_12280	COG0714	Associated with various cellular activities
AKMU_12290	COG2311	Membrane
AKMU_12330	COG1090	epimerase
AKMU_12350	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AKMU_12360	COG1119	ATPase activity
AKMU_12370	COG2186	Transcriptional regulator
AKMU_12410	COG0148	phosphopyruvate hydratase activity
AKMU_12430	COG1477	protein flavinylation
AKMU_12460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AKMU_12480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKMU_12520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AKMU_12540	COG1199	ATP-dependent helicase activity
AKMU_12550	COG1122	ATPase activity
AKMU_12600	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AKMU_12620	COG0359	binds to the 23S rRNA
AKMU_12630	COG0138	bifunctional purine biosynthesis protein purh
AKMU_12640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AKMU_12650	COG0736	holo-[acyl-carrier-protein] synthase activity
AKMU_12670	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AKMU_12680	COG5632	N-Acetylmuramoyl-L-alanine amidase
AKMU_12680	COG3409	Peptidoglycan-binding domain 1 protein
AKMU_12690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKMU_12710	COG0437	4 iron, 4 sulfur cluster binding
AKMU_12750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AKMU_12790	COG0284	orotidine-5'-phosphate decarboxylase activity
AKMU_12830	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AKMU_12840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKMU_12990	COG0305	Participates in initiation and elongation during chromosome replication
AKMU_13240	COG2003	Belongs to the UPF0758 family
AKMU_13250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AKMU_13250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AKMU_13260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKMU_13270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKMU_13280	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AKMU_13290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AKMU_13310	COG0811	peptide transport
AKMU_13320	COG0848	biopolymer transport protein
AKMU_13340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AKMU_13360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AKMU_13380	COG1482	cell wall glycoprotein biosynthetic process
AKMU_13400	COG1757	Na H antiporter
AKMU_13410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKMU_13420	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AKMU_13430	COG0505	Belongs to the CarA family
AKMU_13440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AKMU_13470	COG0070	glutamate synthase
AKMU_13470	COG0069	glutamate synthase activity
AKMU_13470	COG0067	glutamate synthase
AKMU_13480	COG0706	membrane insertase activity
AKMU_13490	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AKMU_13510	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AKMU_13530	COG0657	acetylesterase activity
AKMU_13530	COG2755	lipolytic protein G-D-S-L family
AKMU_13550	COG0676	glucose-6-phosphate 1-epimerase activity
AKMU_13590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKMU_13620	COG1760	l-serine dehydratase
AKMU_13630	COG3118	belongs to the thioredoxin family
AKMU_13630	COG0492	ferredoxin-NADP+ reductase activity
AKMU_13730	COG1408	metallophosphoesterase
AKMU_13750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AKMU_13760	COG0545	Peptidyl-prolyl cis-trans isomerase
AKMU_13780	COG0187	DNA topoisomerase II activity
AKMU_13790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKMU_13810	COG0826	peptidase U32
AKMU_13830	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AKMU_13870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AKMU_13890	COG1116	anion transmembrane transporter activity
AKMU_13910	COG2895	sulfate adenylyltransferase (ATP) activity
AKMU_13910	COG0529	Catalyzes the synthesis of activated sulfate
AKMU_13920	COG0175	sulfate reduction
AKMU_13930	COG0175	sulfate reduction
AKMU_13970	COG0581	inorganic phosphate transmembrane transporter activity
AKMU_13980	COG0573	inorganic phosphate transmembrane transporter activity
AKMU_14000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AKMU_14020	COG2017	converts alpha-aldose to the beta-anomer
AKMU_14050	COG0612	Peptidase, M16
AKMU_14140	COG0233	cytoplasmic translational termination
AKMU_14150	COG0528	UMP kinase activity
AKMU_14160	COG0668	transmembrane transport
AKMU_14170	COG0450	alkyl hydroperoxide reductase
AKMU_14180	COG0733	neurotransmitter:sodium symporter activity
AKMU_14230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AKMU_14240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKMU_14250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKMU_14280	COG0842	Transport permease protein
AKMU_14290	COG0842	Transport permease protein
AKMU_14300	COG1131	(ABC) transporter
AKMU_14320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKMU_14330	COG1183	phosphatidylcholine synthase activity
AKMU_14350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AKMU_14370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AKMU_14380	COG1028	Short-chain dehydrogenase reductase Sdr
AKMU_14420	COG0156	8-amino-7-oxononanoate synthase activity
AKMU_14450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AKMU_14460	COG0124	histidyl-tRNA synthetase
AKMU_14470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AKMU_14480	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AKMU_14490	COG0298	carbon dioxide binding
AKMU_14530	COG0438	transferase activity, transferring glycosyl groups
AKMU_14540	COG0443	Heat shock 70 kDa protein
AKMU_14550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKMU_14560	COG0459	protein refolding
AKMU_14650	COG0632	four-way junction helicase activity
AKMU_14670	COG0126	phosphoglycerate kinase activity
AKMU_14700	COG1082	Xylose isomerase domain protein TIM barrel
AKMU_14710	COG4991	sh3 domain protein
AKMU_14710	COG0515	serine threonine protein kinase
AKMU_14710	COG3064	Membrane
AKMU_14720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKMU_14740	COG2271	Major facilitator Superfamily
AKMU_14770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AKMU_14790	COG0037	tRNA processing
AKMU_14810	COG0254	rRNA binding
AKMU_14850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AKMU_14860	COG0039	L-malate dehydrogenase activity
AKMU_14900	COG0778	Nitroreductase
AKMU_14910	COG0564	pseudouridine synthase activity
AKMU_14950	COG1126	abc transporter atp-binding protein
AKMU_14960	COG0765	amino acid transport
AKMU_15190	COG2856	Zn peptidase
AKMU_15220	COG4085	toxin activity
AKMU_15220	COG0737	Belongs to the 5'-nucleotidase family
AKMU_15220	COG1525	nuclease
AKMU_15420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AKMU_15430	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AKMU_15460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AKMU_15510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AKMU_15520	COG1872	DUF167
AKMU_15540	COG0484	heat shock protein binding
AKMU_15550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AKMU_15570	COG5434	Belongs to the glycosyl hydrolase 28 family
AKMU_15600	COG0277	FAD linked oxidase domain protein
AKMU_15650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKMU_15660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AKMU_15690	COG0131	Imidazoleglycerol-phosphate dehydratase
AKMU_15700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AKMU_15710	COG0360	Binds together with S18 to 16S ribosomal RNA
AKMU_15720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AKMU_15750	COG1686	Belongs to the peptidase S11 family
AKMU_15760	COG0205	6-phosphofructokinase activity
AKMU_15780	COG0428	transporter
AKMU_15790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKMU_15820	COG3977	Valine--pyruvate aminotransferase
AKMU_15830	COG1561	YicC-like family, N-terminal region
AKMU_15850	COG3273	potassium ion transport
AKMU_15850	COG0471	metal ion transport
AKMU_15860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKMU_15890	COG1575	Belongs to the MenA family. Type 1 subfamily
AKMU_15900	COG0710	3-dehydroquinate dehydratase activity
AKMU_15950	COG0726	polysaccharide deacetylase
AKMU_15960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AKMU_15960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AKMU_16000	COG0202	RNA polymerase activity
AKMU_16010	COG0203	ribosomal protein L17
AKMU_16020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AKMU_16030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKMU_16060	COG2885	chlorophyll binding
AKMU_16130	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AKMU_16210	COG0667	Aldo Keto reductase
AKMU_16220	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AKMU_16260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKMU_16270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKMU_16280	COG0134	indole-3-glycerol-phosphate synthase activity
AKMU_16290	COG0135	phosphoribosylanthranilate isomerase activity
AKMU_16310	COG0159	tryptophan synthase activity
AKMU_16340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKMU_16350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AKMU_16370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKMU_16430	COG0561	phosphatase activity
AKMU_16440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKMU_16450	COG2223	nitrite transmembrane transporter activity
AKMU_16500	COG1403	HNH endonuclease
AKMU_16510	COG0305	Participates in initiation and elongation during chromosome replication
AKMU_16730	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKMU_16910	COG0863	Belongs to the N(4) N(6)-methyltransferase family
AKMU_16990	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AKMU_17020	COG1715	Restriction endonuclease
AKMU_17150	COG0556	nucleotide-excision repair
AKMU_17160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AKMU_17170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKMU_17180	COG0750	zinc metalloprotease
AKMU_17210	COG1074	ATP-dependent DNA helicase activity
AKMU_17230	COG0697	spore germination
AKMU_17240	COG2373	Large extracellular alpha-helical protein
AKMU_17250	COG1979	alcohol dehydrogenase
AKMU_17260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AKMU_17310	COG0372	Belongs to the citrate synthase family
AKMU_17350	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AKMU_17370	COG1187	pseudouridine synthase activity
AKMU_17390	COG0105	UTP biosynthetic process
AKMU_17400	COG1215	transferase activity, transferring glycosyl groups
AKMU_17410	COG0463	Glycosyl transferase, family 2
AKMU_17430	COG1459	type II secretion system
AKMU_17440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AKMU_17460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKMU_17490	COG0728	peptidoglycan biosynthetic process
AKMU_17500	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AKMU_17500	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AKMU_17520	COG1649	PFAM Uncharacterised BCR, COG1649
AKMU_17530	COG1691	(AIR) carboxylase
AKMU_17540	COG0037	tRNA processing
AKMU_17550	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AKMU_17560	COG0142	geranyltranstransferase activity
AKMU_17590	COG2151	metal-sulfur cluster biosynthetic enzyme
AKMU_17630	COG1007	ATP synthesis coupled electron transport
AKMU_17640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKMU_17660	COG0713	ATP synthesis coupled electron transport
AKMU_17670	COG0839	Belongs to the complex I subunit 6 family
AKMU_17690	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AKMU_17700	COG1034	ATP synthesis coupled electron transport
AKMU_17710	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AKMU_17720	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AKMU_17730	COG0649	NAD binding
AKMU_17750	COG0726	polysaccharide deacetylase
AKMU_17770	COG0307	riboflavin synthase, alpha
AKMU_17780	COG2264	protein methyltransferase activity
AKMU_17790	COG3210	domain, Protein
AKMU_17800	COG1640	4-alpha-glucanotransferase
AKMU_17820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AKMU_17830	COG1030	water channel activity
AKMU_17840	COG0358	DNA primase activity
AKMU_17850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AKMU_17860	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AKMU_17890	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKMU_17900	COG0793	Belongs to the peptidase S41A family
AKMU_17920	COG1643	Atp-dependent helicase
AKMU_17970	COG1450	Type ii and iii secretion system protein
AKMU_18000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AKMU_18040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKMU_18050	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AKMU_18070	COG0268	Binds directly to 16S ribosomal RNA
AKMU_18080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AKMU_18090	COG0028	Belongs to the TPP enzyme family
AKMU_18100	COG0688	phosphatidylethanolamine metabolic process
AKMU_18110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AKMU_18120	COG0495	leucyl-tRNA aminoacylation
AKMU_18130	COG3119	arylsulfatase activity
AKMU_18160	COG1166	arginine decarboxylase activity
AKMU_18190	COG3250	beta-galactosidase activity
AKMU_18200	COG3250	beta-galactosidase activity
AKMU_18210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AKMU_18220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_18240	COG0205	6-phosphofructokinase activity
AKMU_18330	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AKMU_18340	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AKMU_18350	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AKMU_18370	COG4771	TonB-dependent receptor
AKMU_18420	COG0402	S-adenosylhomocysteine deaminase activity
AKMU_18430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKMU_18480	COG1294	oxidase, subunit
AKMU_18490	COG1271	oxidase subunit
AKMU_18510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKMU_18550	COG1846	Transcriptional regulator
AKMU_18590	COG2949	membrane
AKMU_18620	COG0514	ATP-dependent DNA helicase (RecQ)
AKMU_18640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AKMU_18650	COG0045	succinate-CoA ligase (ADP-forming) activity
AKMU_18770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKMU_18780	COG2205	protein histidine kinase activity
AKMU_18810	COG0113	porphobilinogen synthase activity
AKMU_18830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKMU_18840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AKMU_18870	COG0732	type I restriction modification DNA specificity domain
AKMU_18900	COG0732	type I restriction modification DNA specificity domain
AKMU_18920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AKMU_18980	COG4106	trans-aconitate 2-methyltransferase activity
AKMU_19010	COG3475	LICD family
AKMU_19020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AKMU_19040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKMU_19050	COG3475	LICD family
AKMU_19060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AKMU_19080	COG2166	iron-sulfur cluster assembly
AKMU_19090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKMU_19110	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKMU_19120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AKMU_19130	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AKMU_19140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AKMU_19150	COG1131	(ABC) transporter
AKMU_19180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AKMU_19210	COG1215	transferase activity, transferring glycosyl groups
AKMU_19230	COG2967	ApaG domain
AKMU_19250	COG1522	sequence-specific DNA binding
AKMU_19260	COG0436	Aminotransferase
AKMU_19290	COG0423	glycine-tRNA ligase activity
AKMU_19300	COG0656	L-ascorbic acid biosynthetic process
AKMU_19360	COG0714	Associated with various cellular activities
AKMU_19370	COG0154	amidase activity
AKMU_19380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKMU_19450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKMU_19460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKMU_19530	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AKMU_19550	COG0656	L-ascorbic acid biosynthetic process
AKMU_19570	COG0667	Aldo Keto reductase
AKMU_19580	COG1408	metallophosphoesterase
AKMU_19620	COG2249	NAD(P)H dehydrogenase (quinone) activity
AKMU_19630	COG0789	Transcriptional regulator
AKMU_19660	COG0534	Mate efflux family protein
AKMU_19700	COG1091	dTDP-4-dehydrorhamnose reductase activity
AKMU_19710	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AKMU_19730	COG1837	Belongs to the UPF0109 family
AKMU_19750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AKMU_19760	COG0363	glucosamine-6-phosphate deaminase activity
AKMU_19800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AKMU_19820	COG1741	Belongs to the pirin family
AKMU_19860	COG1070	Carbohydrate kinase
AKMU_19890	COG0738	Major facilitator superfamily
AKMU_19920	COG1595	DNA-templated transcription, initiation
AKMU_19960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AKMU_20000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKMU_20020	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AKMU_20030	COG2132	Multicopper oxidase
AKMU_20050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKMU_20060	COG4608	Belongs to the ABC transporter superfamily
AKMU_20070	COG0444	Belongs to the ABC transporter superfamily
AKMU_20080	COG4166	transmembrane transport
AKMU_20090	COG4239	(ABC) transporter, permease
AKMU_20100	COG0601	transmembrane transport
AKMU_20140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AKMU_20150	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AKMU_20160	COG3738	Protein conserved in bacteria
AKMU_20170	COG0151	Belongs to the GarS family
AKMU_20200	COG0811	peptide transport
AKMU_20220	COG0242	peptide deformylase activity
AKMU_20310	COG3258	Cytochrome c
AKMU_20340	COG3274	enterobacterial common antigen metabolic process
AKMU_20350	COG0538	isocitrate dehydrogenase activity
AKMU_20380	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AKMU_20390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKMU_20400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AKMU_20420	COG0668	transmembrane transport
AKMU_20430	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AKMU_20430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKMU_20440	COG0805	protein transport
AKMU_20450	COG1968	undecaprenyl-diphosphatase activity
AKMU_20490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AKMU_20500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKMU_20520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AKMU_20540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AKMU_20560	COG1408	metallophosphoesterase
AKMU_20610	COG4974	Belongs to the 'phage' integrase family
AKMU_20650	COG1454	alcohol dehydrogenase
AKMU_20660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKMU_20680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AKMU_20680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AKMU_20690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AKMU_20760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AKMU_20780	COG4607	ABC-type enterochelin transport system periplasmic component
AKMU_20790	COG4604	ABC transporter, ATP-binding protein
AKMU_20800	COG4605	iron ion homeostasis
AKMU_20810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKMU_20880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKMU_20880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKMU_20910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AKMU_20920	COG2195	Cleaves the N-terminal amino acid of tripeptides
AKMU_21000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKMU_21050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AKMU_21050	COG0519	Catalyzes the synthesis of GMP from XMP
AKMU_21060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKMU_21120	COG0646	methionine synthase
AKMU_21120	COG1410	methionine synthase
AKMU_21130	COG2966	Psort location CytoplasmicMembrane, score
AKMU_21140	COG3610	response to peptide
AKMU_21150	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AKMU_21190	COG4974	Belongs to the 'phage' integrase family
AKMU_21210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AKMU_21220	COG0460	homoserine dehydrogenase
AKMU_21230	COG0527	aspartate kinase activity
AKMU_21250	COG5522	Integral membrane protein (intg_mem_TP0381)
AKMU_21270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKMU_21280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKMU_21290	COG1194	a g-specific adenine glycosylase
AKMU_21300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AKMU_21310	COG0574	Belongs to the PEP-utilizing enzyme family
AKMU_21310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKMU_21320	COG0166	Belongs to the GPI family
AKMU_21340	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AKMU_21370	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AKMU_21370	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AKMU_21440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AKMU_21450	COG2818	Glycosylase
AKMU_21490	COG3033	Beta-eliminating lyase
AKMU_21520	COG0072	phenylalanine-tRNA ligase activity
AKMU_21520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKMU_21560	COG0326	Molecular chaperone. Has ATPase activity
AKMU_21570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AKMU_21580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKMU_21590	COG1959	2 iron, 2 sulfur cluster binding
AKMU_21620	COG0352	thiamine-phosphate diphosphorylase activity
AKMU_21630	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AKMU_21670	COG1703	isobutyryl-CoA mutase activity
AKMU_21710	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AKMU_21730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AKMU_21740	COG0418	dihydroorotase activity
AKMU_21760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKMU_21800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKMU_21830	COG0534	Mate efflux family protein
AKMU_21840	COG0489	protein tyrosine kinase activity
AKMU_21860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKMU_21870	COG0339	signal peptide processing
AKMU_21880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKMU_21900	COG1538	Outer membrane efflux protein
AKMU_21930	COG4112	unkown
AKMU_21960	COG0038	chloride channel
AKMU_21980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AKMU_21990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKMU_22000	COG0586	Pfam SNARE associated Golgi protein
AKMU_22130	COG1012	belongs to the aldehyde dehydrogenase family
AKMU_22170	COG0753	catalase activity
AKMU_22180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AKMU_22190	COG1592	Rubrerythrin
AKMU_22200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AKMU_22240	COG0489	protein tyrosine kinase activity
AKMU_22260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AKMU_22280	COG0438	transferase activity, transferring glycosyl groups
AKMU_22300	COG0438	transferase activity, transferring glycosyl groups
AKMU_22380	COG0110	maltose O-acetyltransferase activity
AKMU_22400	COG1216	Glycosyl transferase, family 2
AKMU_22410	COG1216	Glycosyl transferase, family 2
AKMU_22500	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AKMU_22510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKMU_22510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKMU_22520	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AKMU_22540	COG0281	malic enzyme
AKMU_22540	COG0280	phosphate acetyltransferase
AKMU_22570	COG1472	Belongs to the glycosyl hydrolase 3 family
AKMU_22610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AKMU_22630	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AKMU_22640	COG1063	alcohol dehydrogenase
AKMU_22670	COG0714	Associated with various cellular activities
AKMU_22690	COG0193	aminoacyl-tRNA hydrolase activity
AKMU_22700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKMU_22730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKMU_22770	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AKMU_22800	COG0375	protein maturation
AKMU_22840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_22850	COG0778	Nitroreductase
AKMU_22860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKMU_22900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AKMU_22900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AKMU_22920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AKMU_22920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AKMU_22960	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AKMU_22970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKMU_23120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKMU_23130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AKMU_23160	COG0318	PFAM AMP-dependent synthetase and ligase
AKMU_23220	COG0339	signal peptide processing
AKMU_23240	COG0018	arginyl-trna synthetase
AKMU_23290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AKMU_23300	COG0653	protein targeting
AKMU_23320	COG0494	nUDIX hydrolase
AKMU_P340	COG1783	phage Terminase large subunit