locus-tag	class	description
A4V05_00035	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4V05_00055	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A4V05_00060	ENOG4107QM5	aconitate hydratase
A4V05_00085	ENOG4105E0Y	RtcB Protein
A4V05_00095	ENOG4105CZM	Major Facilitator
A4V05_00105	ENOG4108WBT	adenosyltransferase
A4V05_00115	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A4V05_00120	ENOG4105CFP	Peptidase U32
A4V05_00125	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A4V05_00140	ENOG410823G	oxidoreductase
A4V05_00145	ENOG4105C0D	helicase
A4V05_00150	ENOG4105CGH	5'-nucleotidase
A4V05_00155	ENOG4105K6T	rare lipoprotein A
A4V05_00160	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A4V05_00165	ENOG41082A0	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A4V05_00175	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A4V05_00180	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A4V05_00185	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A4V05_00190	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A4V05_00195	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A4V05_00200	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A4V05_00205	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A4V05_00210	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A4V05_00225	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A4V05_00240	ENOG4105K64	Glycosyl transferase, family 2
A4V05_00250	ENOG4105K64	Glycosyl transferase, family 2
A4V05_00265	ENOG4105K64	Glycosyl transferase, family 2
A4V05_00270	ENOG4108Z0Z	intracellular protease Pfpi family
A4V05_00275	ENOG4105C7S	Dehydrogenase
A4V05_00280	ENOG4105CE4	GlcNAc 6-P deacetylase
A4V05_00285	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
A4V05_00310	ENOG4105ENH	Sulfatase
A4V05_00315	ENOG41084NN	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
A4V05_00320	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A4V05_00325	ENOG4105CHV	Transcription elongation factor NusA
A4V05_00330	ENOG4105CGK	Exodeoxyribonuclease III
A4V05_00335	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A4V05_00360	ENOG4105IDI	abc transporter atp-binding protein
A4V05_00380	ENOG4105VFU	Rna-binding protein
A4V05_00385	ENOG4105D3Q	Sugar transferase
A4V05_00415	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
A4V05_00420	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
A4V05_00425	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
A4V05_00430	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A4V05_00445	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A4V05_00475	ENOG4105E33	succinate dehydrogenase
A4V05_00530	ENOG4105CHR	reductase
A4V05_00540	ENOG4105C5H	ABC transporter
A4V05_00550	ENOG4105MS2	ribosomal subunit Interface protein
A4V05_00565	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A4V05_00575	ENOG4105ENX	hydrolase
A4V05_00585	ENOG4105CPC	Aldo Keto reductase
A4V05_00640	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A4V05_00645	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
A4V05_00685	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
A4V05_00690	ENOG4105C5H	ABC transporter
A4V05_00700	ENOG410631K	Membrane
A4V05_00710	ENOG4105C8N	cysteinyl-tRNA synthetase
A4V05_00715	ENOG4105E2D	ec 3.2.1.52
A4V05_00720	ENOG4105CBG	Sulfatase
A4V05_00735	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
A4V05_00755	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4V05_00760	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4V05_00765	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
A4V05_00770	ENOG4107Z3D	50S ribosomal protein l10
A4V05_00775	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A4V05_00780	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A4V05_00785	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A4V05_00800	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A4V05_00810	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4V05_00820	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
A4V05_00825	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A4V05_00830	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4V05_00840	ENOG4105SYT	Methylenetetrahydrofolate reductase
A4V05_00860	ENOG4108IJF	Heavy metal efflux pump, CzcA
A4V05_00905	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
A4V05_00910	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
A4V05_00915	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A4V05_00945	ENOG4105CBG	Sulfatase
A4V05_00950	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4V05_00960	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
A4V05_00970	ENOG4108IYU	L-aspartate oxidase
A4V05_00975	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A4V05_01025	ENOG4105CE1	Ferrous iron transport protein b
A4V05_01040	ENOG4105CA0	peroxidase
A4V05_01045	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A4V05_01050	ENOG4108Z6B	deaminase
A4V05_01055	ENOG4105DKQ	ROK family
A4V05_01060	ENOG4105C59	p-type ATPase
A4V05_01065	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A4V05_01070	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A4V05_01075	ENOG4105GVR	general secretion pathway protein D
A4V05_01105	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A4V05_01115	ENOG4107RAQ	aminopeptidase
A4V05_01120	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A4V05_01135	ENOG4105BZU	Histidine kinase
A4V05_01140	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A4V05_01145	ENOG4105C01	Dihydroxy-acid dehydratase
A4V05_01170	ENOG4105E0M	Sulfatase
A4V05_01205	ENOG4105CMR	udp-glucose 4-epimerase
A4V05_01210	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A4V05_01230	ENOG4107QI1	Mate efflux family protein
A4V05_01320	ENOG4105CNA	YD repeat protein
A4V05_01365	ENOG4105CNA	YD repeat protein
A4V05_01395	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A4V05_01400	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A4V05_01405	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
A4V05_01410	ENOG4105C08	Histidine kinase
A4V05_01430	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A4V05_01445	ENOG4105CPC	Aldo Keto reductase
A4V05_01450	ENOG4105V75	Transcriptional regulator
A4V05_01500	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4V05_01545	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
A4V05_01550	ENOG4105DKW	ABC transporter
A4V05_01555	ENOG4105C6F	GntR Family Transcriptional Regulator
A4V05_01570	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A4V05_01580	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A4V05_01585	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
A4V05_01590	ENOG4105CJ2	(LipO)protein
A4V05_01605	ENOG41085AM	50S ribosomal protein L28
A4V05_01620	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
A4V05_01625	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
A4V05_01635	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
A4V05_01640	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
A4V05_01650	ENOG4105DVT	helicase
A4V05_01655	ENOG4108JJB	ABC transporter
A4V05_01680	ENOG4105CAS	nag kinase
A4V05_01690	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
A4V05_01695	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A4V05_01700	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A4V05_01705	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
A4V05_01715	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A4V05_01720	ENOG4108VPC	n-acetylmuramoyl-l-alanine amidase
A4V05_01735	ENOG4107SFQ	iron-sulfur binding
A4V05_01755	ENOG4105D49	3-dehydroquinate synthase
A4V05_01810	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
A4V05_01830	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A4V05_01855	ENOG4105W5Q	DNA repair protein (RadC
A4V05_01860	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A4V05_01865	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A4V05_01870	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A4V05_01875	ENOG4108UJD	30S ribosomal protein S9
A4V05_01880	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
A4V05_01885	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
A4V05_01895	ENOG4109015	Biopolymer transport protein exbD tolR
A4V05_01905	ENOG4108JQC	penicillin-binding protein 1A
A4V05_01915	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A4V05_01925	ENOG4105DG6	mannose-6-phosphate isomerase
A4V05_01935	ENOG4105DFD	Na H antiporter
A4V05_01940	ENOG4105C30	Nad-dependent epimerase dehydratase
A4V05_01945	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
A4V05_01950	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A4V05_01955	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A4V05_01965	ENOG4105CBC	glutamate synthase
A4V05_01975	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
A4V05_01980	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
A4V05_02010	ENOG4105DSB	aldose 1-epimerase
A4V05_02015	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A4V05_02020	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A4V05_02030	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A4V05_02050	ENOG4105EJQ	L-serine dehydratase
A4V05_02055	ENOG4105C3M	thioredoxin reductase
A4V05_02110	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A4V05_02115	ENOG4105DIN	metallophosphoesterase
A4V05_02125	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A4V05_02130	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A4V05_02145	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4V05_02150	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A4V05_02160	ENOG4105CFP	Peptidase U32
A4V05_02165	ENOG4105E6M	Sulphatase-modifying factor protein
A4V05_02185	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A4V05_02190	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4V05_02195	ENOG4105E2Z	phosphate ABC transporter (Permease
A4V05_02200	ENOG4105C8U	phosphate abc transporter
A4V05_02210	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A4V05_02220	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A4V05_02235	ENOG4105C1V	Peptidase, M16
A4V05_02245	ENOG4108UW5	maltose o-acetyltransferase
A4V05_02295	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
A4V05_02300	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A4V05_02310	ENOG4105D3R	alkyl hydroperoxide reductase
A4V05_02315	ENOG4105C8J	)-transporter
A4V05_02330	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A4V05_02340	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A4V05_02345	ENOG4105E0X	reductase
A4V05_02350	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A4V05_02375	ENOG4107QWP	ABC-2 type transporter
A4V05_02380	ENOG4107QWP	ABC-2 type transporter
A4V05_02385	ENOG4105CJ1	ABC, transporter
A4V05_02395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A4V05_02400	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A4V05_02410	ENOG4105EEI	dihydropteroate synthase
A4V05_02420	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A4V05_02425	ENOG4105CHR	reductase
A4V05_02450	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A4V05_02475	ENOG4105C9M	aspartyl-trna synthetase
A4V05_02480	ENOG4105CUT	histidyl-tRNA synthetase
A4V05_02500	ENOG4105CQS	hydrogenase expression formation protein HypD
A4V05_02525	ENOG4105CFG	Acts as a chaperone (By similarity)
A4V05_02530	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A4V05_02535	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A4V05_02570	ENOG4105D75	Capsular exopolysaccharide family
A4V05_02585	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
A4V05_02595	ENOG4105BZA	Phosphoglycerate kinase
A4V05_02610	ENOG4105CGS	Alpha-glucosidase
A4V05_02620	ENOG4108JA2	transcriptioN-repair coupling factor
A4V05_02630	ENOG4105DJB	Major Facilitator Superfamily
A4V05_02645	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
A4V05_02650	ENOG4105C6K	Malic enzyme
A4V05_02655	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A4V05_02660	ENOG4105NRA	50s ribosomal protein l31 type b
A4V05_02695	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A4V05_02700	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A4V05_02725	ENOG4108RCM	Nitroreductase
A4V05_02730	ENOG4105C34	Pseudouridine synthase
A4V05_02735	ENOG4105I08	Pseudouridine synthase
A4V05_02760	ENOG4105CDA	abc transporter atp-binding protein
A4V05_02775	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A4V05_02780	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
A4V05_02805	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4V05_02835	ENOG4105VZ9	UPF0235 protein
A4V05_02840	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A4V05_02845	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A4V05_02850	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A4V05_02860	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
A4V05_02875	ENOG4105CQB	FAD linked oxidase domain protein
A4V05_02900	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A4V05_02905	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
A4V05_02915	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A4V05_02920	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A4V05_02925	ENOG4107Q5Z	Binds together with S18 to 16S ribosomal RNA (By similarity)
A4V05_02930	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A4V05_02945	ENOG4105DZ1	carboxypeptidase
A4V05_02950	ENOG4105CTQ	phosphohexokinase
A4V05_02960	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
A4V05_02965	ENOG4105MH8	Thioredoxin disulfide isomerase
A4V05_02980	ENOG4105JKW	Valine--pyruvate aminotransferase
A4V05_02985	ENOG4105DSJ	YicC domain protein
A4V05_03000	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
A4V05_03015	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
A4V05_03020	ENOG4105FF2	Type I DHQase
A4V05_03040	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A4V05_03050	ENOG4108ZJ4	polysaccharide deacetylase
A4V05_03055	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4V05_03065	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
A4V05_03075	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A4V05_03080	ENOG4108ZT0	50S ribosomal protein l17
A4V05_03085	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A4V05_03095	ENOG4107YBY	Hydrolase
A4V05_03110	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A4V05_03150	ENOG4105C0D	helicase
A4V05_03160	ENOG4107QMH	DNA methylase
A4V05_03190	ENOG4105CPC	Aldo Keto reductase
A4V05_03195	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A4V05_03215	ENOG4105CRQ	synthase (Component I)
A4V05_03220	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A4V05_03225	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A4V05_03230	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
A4V05_03240	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A4V05_03260	ENOG4105DWV	Homoserine O-trans-acetylase
A4V05_03265	ENOG4105YK5	50S ribosomal protein L36
A4V05_03275	ENOG4105F1A	Pyruvate formate-lyase
A4V05_03310	ENOG4108HCJ	Hydrolase
A4V05_03315	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A4V05_03320	ENOG4106UW1	Major Facilitator superfamily
A4V05_03340	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A4V05_03350	ENOG4105VJV	50s ribosomal protein L35
A4V05_03355	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
A4V05_03360	ENOG4105DZP	Membrane-associated zinc metalloprotease
A4V05_03375	ENOG4107QKA	exodeoxyribonuclease V beta
A4V05_03390	ENOG410631K	Membrane
A4V05_03395	ENOG4107S85	alpha-2-macroglobulin domain protein
A4V05_03400	ENOG4107QW4	alcohol dehydrogenase
A4V05_03410	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A4V05_03435	ENOG4105BZN	citrate synthase
A4V05_03455	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
A4V05_03465	ENOG4108R99	pseudouridine synthase
A4V05_03475	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A4V05_03485	ENOG4105CKK	Glycosyl transferase, family 2
A4V05_03495	ENOG4105D7Q	type ii secretion system
A4V05_03500	ENOG4107QHF	type ii secretion system protein e
A4V05_03505	ENOG4107QHF	type ii secretion system protein e
A4V05_03510	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A4V05_03525	ENOG4105CJR	Integral membrane protein (MviN
A4V05_03530	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A4V05_03545	ENOG4105F32	YngK protein
A4V05_03550	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
A4V05_03555	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A4V05_03560	ENOG4105C8M	UPF0272 protein
A4V05_03565	ENOG4105EAH	synthase
A4V05_03580	ENOG4105VG1	fes assembly suf system protein
A4V05_03595	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4V05_03600	ENOG4105C8S	subunit m
A4V05_03610	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4V05_03615	ENOG4107UFS	subunit j
A4V05_03625	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A4V05_03630	ENOG4108IEH	NADH dehydrogenase subunit g
A4V05_03635	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
A4V05_03640	ENOG4105GKE	subunit e
A4V05_03645	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4V05_03655	ENOG4107BJW	polysaccharide deacetylase
A4V05_03665	ENOG4108R6K	riboflavin synthase, subunit alpha
A4V05_03675	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A4V05_03690	ENOG4107S1W	4-alpha-glucanotransferase
A4V05_03705	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
A4V05_03710	ENOG4105F7J	membrane-bound serine protease
A4V05_03715	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A4V05_03720	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4V05_03725	ENOG4108UQS	dipeptidase
A4V05_03740	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A4V05_03745	ENOG4105CN1	protease
A4V05_03760	ENOG4105CQ7	ATP-dependent helicase
A4V05_03785	ENOG4105GVR	general secretion pathway protein D
A4V05_03800	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A4V05_03820	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
A4V05_03825	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
A4V05_03835	ENOG410872P	Binds directly to 16S ribosomal RNA (By similarity)
A4V05_03840	ENOG4107VXZ	Hydrolase
A4V05_03845	ENOG4105C7K	acetolactate synthase
A4V05_03850	ENOG4105DJ4	phosphatidylserine decarboxylase
A4V05_03860	ENOG4105C8T	Leucyl-tRNA synthetase
A4V05_03865	ENOG4105ENH	Sulfatase
A4V05_03880	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
A4V05_03895	ENOG4105CNT	hydrolase family 2
A4V05_03900	ENOG4105CNT	hydrolase family 2
A4V05_03905	ENOG4105D1H	recombination factor protein RarA
A4V05_03910	ENOG4105E2D	ec 3.2.1.52
A4V05_03925	ENOG4105CTQ	phosphohexokinase
A4V05_03950	ENOG4108YZT	Adenosylcobinamide kinase
A4V05_03960	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A4V05_03965	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
A4V05_03970	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A4V05_03975	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A4V05_03985	ENOG4107ENK	receptor
A4V05_04010	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A4V05_04015	ENOG4107QN2	dihydrolipoyl dehydrogenase
A4V05_04035	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A4V05_04040	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A4V05_04045	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A4V05_04055	ENOG4107WAU	Protein tyrosine phosphatase
A4V05_04075	ENOG410834F	Transcriptional regulator
A4V05_04200	ENOG4105CDU	Replicative dna helicase
A4V05_04325	ENOG4108UB4	uncharacterized protein ygjQ
A4V05_04355	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A4V05_04370	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A4V05_04375	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
A4V05_04380	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A4V05_04410	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A4V05_04415	ENOG4105CEY	Amp-dependent synthetase and ligase
A4V05_04445	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A4V05_04450	ENOG41065SU	Two-component system sensor kinase
A4V05_04465	ENOG4105D52	delta-aminolevulinic acid dehydratase
A4V05_04480	ENOG4105C22	threonyL-tRNA synthetase
A4V05_04485	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
A4V05_04500	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
A4V05_04525	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A4V05_04540	ENOG4105KPE	licD family
A4V05_04545	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
A4V05_04555	ENOG4105KPE	licD family
A4V05_04560	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
A4V05_04575	ENOG4105KPE	licD family
A4V05_04580	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A4V05_04590	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A4V05_04595	ENOG4105DBV	ornithine carbamoyltransferase
A4V05_04600	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A4V05_04605	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A4V05_04610	ENOG41080Z8	PHOSPHOCARRIER protein
A4V05_04615	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A4V05_04620	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A4V05_04625	ENOG4105DA5	(ABC) transporter
A4V05_04640	ENOG4105DFA	alanine racemase domain protein
A4V05_04655	ENOG4105CND	Glycosyl transferase, family 2
A4V05_04665	ENOG4105NWN	ApaG protein
A4V05_04675	ENOG4108ZB6	transcriptional regulator AsnC family
A4V05_04680	ENOG4105CHM	Aminotransferase
A4V05_04695	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A4V05_04705	ENOG4105CV8	reductase
A4V05_04735	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4V05_04740	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A4V05_04745	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A4V05_04785	ENOG4105C0H	protease
A4V05_04800	ENOG4105EXC	Acyl-transferase
A4V05_04830	ENOG4105C87	Aminotransferase class I and II
A4V05_04840	ENOG4105CV8	reductase
A4V05_04845	ENOG4105ENX	hydrolase
A4V05_04850	ENOG4107SET	aldo keto reductase
A4V05_04855	ENOG4105DIN	metallophosphoesterase
A4V05_04875	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
A4V05_04880	ENOG4105VUF	Transcriptional regulator
A4V05_04900	ENOG4105C3S	Mate efflux family protein
A4V05_04910	ENOG4105E2D	ec 3.2.1.52
A4V05_04920	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A4V05_04925	ENOG4105DR4	Methyltransferase
A4V05_04935	ENOG4105VB6	UPF0109 protein
A4V05_04945	ENOG4105DR4	Methyltransferase
A4V05_04950	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
A4V05_04965	ENOG4105DX0	Hemolysin A
A4V05_04975	ENOG4105C2I	pirin domain protein
A4V05_04995	ENOG4105CMG	Carbohydrate kinase
A4V05_05005	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
A4V05_05010	ENOG4105EDR	glucose galactose transporter
A4V05_05045	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A4V05_05070	ENOG4105C0H	protease
A4V05_05085	ENOG4105E3B	Multicopper oxidase
A4V05_05090	ENOG4105EMK	carboxylate amino acid amine transporter
A4V05_05095	ENOG4108HFV	
A4V05_05110	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4V05_05115	ENOG4108JQ7	(ABC) transporter
A4V05_05125	ENOG4108J59	Extracellular solute-binding protein, family 5
A4V05_05130	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
A4V05_05150	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A4V05_05155	ENOG4105CKU	formyltetrahydrofolate synthetase
A4V05_05160	ENOG4108XC3	NADH ubiquinone oxidoreductase
A4V05_05165	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A4V05_05190	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4V05_05230	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
A4V05_05240	ENOG4105NQN	cytochrome C
A4V05_05250	ENOG4105MEV	Acyl-transferase
A4V05_05255	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A4V05_05275	ENOG4105CY0	Metallo-Beta-Lactamase
A4V05_05280	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A4V05_05285	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A4V05_05295	ENOG4105D64	Mechanosensitive ion channel
A4V05_05300	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A4V05_05305	ENOG410845M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes (By similarity)
A4V05_05310	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A4V05_05330	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A4V05_05340	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
A4V05_05350	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
A4V05_05360	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A4V05_05370	ENOG4105DIN	metallophosphoesterase
A4V05_05390	ENOG4105DVP	Adenine-specific
A4V05_05395	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4V05_05415	ENOG4108JB8	alcohol dehydrogenase
A4V05_05420	ENOG4105WMR	Protein CrcB homolog
A4V05_05435	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4V05_05450	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A4V05_05465	ENOG4105E2D	ec 3.2.1.52
A4V05_05480	ENOG4105CRE	cytochrome C
A4V05_05495	ENOG4108IPW	abc transporter atp-binding protein
A4V05_05500	ENOG4105CM4	permease protein
A4V05_05505	ENOG4105DHS	permease protein
A4V05_05550	ENOG4105C2M	dna polymerase I
A4V05_05565	ENOG4105C83	adenylosuccinate lyase
A4V05_05575	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
A4V05_05635	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A4V05_05640	ENOG4108Z66	YbaK ebsC protein
A4V05_05675	ENOG4105C3R	Methionine synthase
A4V05_05680	ENOG4105DWK	Membrane
A4V05_05685	ENOG4107XM3	UPF0442 protein
A4V05_05700	ENOG4105CFH	Aspartokinase
A4V05_05725	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A4V05_05735	ENOG4105E2X	shikimate dehydrogenase
A4V05_05740	ENOG4105CEN	a g-specific adenine glycosylase
A4V05_05745	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
A4V05_05750	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A4V05_05760	ENOG4105C89	phosphohexose isomerase
A4V05_05770	ENOG4105DR4	Methyltransferase
A4V05_05780	ENOG4105D5P	Methylmalonyl-coA mutase
A4V05_05820	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A4V05_05840	ENOG4105C0F	tryptophanase EC 4.1.99.1
A4V05_05855	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A4V05_05875	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
A4V05_05885	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A4V05_05890	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
A4V05_05905	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A4V05_05910	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
A4V05_05925	ENOG4105E2D	ec 3.2.1.52
A4V05_05930	ENOG4105E2D	ec 3.2.1.52
A4V05_05935	ENOG4105DJT	lAO AO transport system ATPase
A4V05_05955	ENOG41081ID	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
A4V05_05960	ENOG4105C1J	atp-dependent rna helicase
A4V05_05965	ENOG4105C5X	domain protein
A4V05_05970	ENOG4105EKE	dihydroorotase
A4V05_05985	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A4V05_05995	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
A4V05_06005	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A4V05_06010	ENOG4107QSA	Oxaloacetate decarboxylase
A4V05_06020	ENOG4107QI1	Mate efflux family protein
A4V05_06040	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A4V05_06045	ENOG4105DGW	oligopeptidase A
A4V05_06050	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
A4V05_06060	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A4V05_06080	ENOG4105U6W	MutT NUDIX family protein
A4V05_06110	ENOG4105D82	Glutamate dehydrogenase
A4V05_06115	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4V05_06120	ENOG4107T5V	SNARE associated Golgi
A4V05_06195	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A4V05_06230	ENOG4105C26	Dehydrogenase
A4V05_06250	ENOG4105CH6	catalase
A4V05_06270	ENOG4105CRE	cytochrome C
A4V05_06275	ENOG4108RAC	Rubrerythrin
A4V05_06280	ENOG41068WN	
A4V05_06290	ENOG4105CNU	cell division protein FtsK
A4V05_06300	ENOG4108QV3	biosynthesis protein
A4V05_06310	ENOG4105D3Q	Sugar transferase
A4V05_06320	ENOG4107XU6	Glycosyl transferase (Group 1
A4V05_06330	ENOG4105E2K	Glycosyl transferase (Group 1
A4V05_06370	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
A4V05_06380	ENOG4105K64	Glycosyl transferase, family 2
A4V05_06385	ENOG4105K64	Glycosyl transferase, family 2
A4V05_06405	ENOG4105EXC	Acyl-transferase
A4V05_06430	ENOG4105C87	Aminotransferase class I and II
A4V05_06440	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A4V05_06445	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
A4V05_06465	ENOG4105C6K	Malic enzyme
A4V05_06480	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A4V05_06485	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A4V05_06500	ENOG4105CSA	Coproporphyrinogen iii oxidase
A4V05_06535	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A4V05_06545	ENOG4105CPQ	Dehydrogenase
A4V05_06560	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A4V05_06570	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
A4V05_06575	ENOG4105BZ4	penicillin-binding protein
A4V05_06590	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A4V05_06610	ENOG4105E3S	small subunit
A4V05_06625	ENOG4108USZ	hydrogenase
A4V05_06630	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
A4V05_06655	ENOG4108RCM	Nitroreductase
A4V05_06660	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A4V05_06680	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A4V05_06690	ENOG4107GFK	fumarate
A4V05_06710	ENOG4105E2D	ec 3.2.1.52
A4V05_06720	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A4V05_06755	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A4V05_06760	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A4V05_06775	ENOG4105CEY	Amp-dependent synthetase and ligase
A4V05_06800	ENOG4105DGW	oligopeptidase A
A4V05_06810	ENOG4105C75	arginyL-tRNA synthetase
A4V05_06850	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4V05_06855	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A4V05_06860	ENOG4107QZM	n-acetylglutamate synthase
A4V05_07055	ENOG4108YZ4	nudix hydrolase
A4V05_07060	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
A4V05_07065	ENOG4105CJ1	ABC, transporter
A4V05_07085	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A4V05_07105	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A4V05_07110	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A4V05_07120	ENOG4105C1J	atp-dependent rna helicase
A4V05_07135	ENOG4105EPC	oxidoreductase
A4V05_07150	ENOG4108ISG	Major Facilitator
A4V05_07155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A4V05_07170	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A4V05_07175	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
A4V05_07205	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A4V05_07230	ENOG4107QP0	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A4V05_07260	ENOG4105E5D	amino acid
A4V05_07265	ENOG4105CSV	Glutaminase
A4V05_07280	ENOG4105BZG	amino acid carrier protein
A4V05_07290	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A4V05_07295	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A4V05_07300	ENOG4105C25	Primosomal protein n'
A4V05_07305	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A4V05_07325	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A4V05_07330	ENOG4107QJQ	Mate efflux family protein
A4V05_07345	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A4V05_07350	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A4V05_07355	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
A4V05_07375	ENOG4105DIK	(ABC) transporter
A4V05_07380	ENOG4105CC5	ABC transporter
A4V05_07385	ENOG4108Z0C	Uvrb UvrC protein
A4V05_07390	ENOG41066A3	ATP guanido phosphotransferase
A4V05_07395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4V05_07410	ENOG4105ERH	Fumarylacetoacetate hydrolase
A4V05_07415	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A4V05_07430	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A4V05_07440	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A4V05_07445	ENOG4105C31	Tryptophanyl-tRNA synthetase
A4V05_07455	ENOG4105D48	metallophosphoesterase
A4V05_07465	ENOG4105CUZ	uba thif-type nad fad binding protein
A4V05_07480	ENOG4105D7K	pfkb domain protein
A4V05_07490	ENOG4105E09	nadh pyrophosphatase
A4V05_07500	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A4V05_07510	ENOG4107QJE	Chromosome Partitioning Protein
A4V05_07520	ENOG4107WDG	serine threonine protein kinase
A4V05_07565	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A4V05_07575	ENOG4105K78	MarR family Transcriptional regulator
A4V05_07585	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A4V05_07590	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A4V05_07600	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A4V05_07605	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
A4V05_07610	ENOG41083ND	50S ribosomal protein L33
A4V05_07615	ENOG4105SCY	DNAK suppressor
A4V05_07620	ENOG4105DKQ	ROK family
A4V05_07625	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A4V05_07635	ENOG4105M6F	mutator MutT protein
A4V05_07640	ENOG4105CW7	secretion protein, HlyD family
A4V05_07645	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4V05_07650	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4V05_07655	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A4V05_07670	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A4V05_07680	ENOG4108R96	Methyltransferase, YaeB family
A4V05_07685	ENOG4105CD3	dihydroorotase
A4V05_07690	ENOG4105CXT	aspartate transcarbamylase
A4V05_07695	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A4V05_07715	ENOG4105DZ0	fad dependent oxidoreductase
A4V05_07720	ENOG4105DWY	Agmatine deiminase
A4V05_07730	ENOG4105DZP	Membrane-associated zinc metalloprotease
A4V05_07740	ENOG41061MV	Arylsulfatase
A4V05_07750	ENOG4105CE1	Ferrous iron transport protein b
A4V05_07775	ENOG4105DF5	DNA topoisomerase IV, subunit A
A4V05_07810	ENOG4105FA0	parb-like partition protein
A4V05_07840	ENOG4105DHU	Bile acid
A4V05_07845	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
A4V05_07860	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A4V05_07865	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A4V05_07870	ENOG4107QSI	ABC, transporter
A4V05_07905	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A4V05_07920	ENOG4105BZ1	(ABC) transporter
A4V05_07925	ENOG4105BZ1	(ABC) transporter
A4V05_07940	ENOG4105DHJ	ABC, transporter
A4V05_07945	ENOG4107PE3	Mammalian cell entry related domain protein
A4V05_07965	ENOG4105CZX	twitching motility protein
A4V05_07970	ENOG4105CZX	twitching motility protein
A4V05_07975	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A4V05_07990	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A4V05_07995	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A4V05_08000	ENOG4107RJ1	sodium solute
A4V05_08030	ENOG4108JQC	penicillin-binding protein 1A
A4V05_08040	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4V05_08045	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4V05_08055	ENOG4105D60	lipoprotein releasing system transmembrane protein
A4V05_08080	ENOG4107VAM	peptidase, m28
A4V05_08090	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A4V05_08095	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A4V05_08110	ENOG4105C9B	Cysteine desulfurase
A4V05_08120	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
A4V05_08130	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
A4V05_08140	ENOG4108ZVT	methylmalonyl-coA epimerase
A4V05_08145	ENOG4107QX3	carboxylase
A4V05_08155	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A4V05_08165	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A4V05_08170	ENOG4105CYC	Transferase
A4V05_08180	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A4V05_08185	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A4V05_08190	ENOG4105CTQ	phosphohexokinase
A4V05_08200	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A4V05_08205	ENOG4105C7K	acetolactate synthase
A4V05_08215	ENOG4107UNZ	domain protein
A4V05_08270	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A4V05_08275	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A4V05_08285	ENOG4105C8P	)-transporter
A4V05_08350	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A4V05_08360	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A4V05_08365	ENOG4105CPQ	Dehydrogenase
A4V05_08375	ENOG4105EYW	Ion transport protein
A4V05_08380	ENOG41080E8	Transcriptional regulator, Spx MgsR family
A4V05_08385	ENOG4105CY0	Metallo-Beta-Lactamase
A4V05_08410	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
A4V05_08415	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A4V05_08425	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A4V05_08475	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A4V05_08480	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4V05_08485	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
A4V05_08490	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A4V05_08530	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4V05_08555	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
A4V05_08565	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
A4V05_08585	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A4V05_08590	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A4V05_08595	ENOG4105K5M	30s ribosomal protein S16
A4V05_08620	ENOG4105VIE	preprotein translocase, subunit YajC
A4V05_08625	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A4V05_08630	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A4V05_08640	ENOG4105K6T	rare lipoprotein A
A4V05_08645	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A4V05_08650	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A4V05_08705	ENOG4105CNT	hydrolase family 2
A4V05_08710	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A4V05_08725	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A4V05_08730	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A4V05_08735	ENOG41082SA	50s ribosomal protein l29
A4V05_08740	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
A4V05_08745	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A4V05_08750	ENOG41080P9	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A4V05_08760	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A4V05_08765	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A4V05_08770	ENOG4108542	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A4V05_08775	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
A4V05_08780	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A4V05_08785	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A4V05_08790	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A4V05_08795	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A4V05_08800	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A4V05_08805	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4V05_08815	ENOG4105BZU	Histidine kinase
A4V05_08820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A4V05_08835	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A4V05_08850	ENOG4108M8S	permease YjgP YjgQ family protein
A4V05_08855	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A4V05_08880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A4V05_08890	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4V05_08920	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A4V05_08935	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A4V05_08945	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
A4V05_08950	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A4V05_08970	ENOG4108IPT	Naphthoate synthase
A4V05_09010	ENOG4107T0D	ABC, transporter
A4V05_09025	ENOG4108IJ6	ABC transporter
A4V05_09035	ENOG4107FW0	short-chain dehydrogenase reductase
A4V05_09050	ENOG4108JUA	Transcriptional regulator
A4V05_09065	ENOG4105E2D	ec 3.2.1.52
A4V05_09080	ENOG4105CVK	Glutamate decarboxylase
A4V05_09090	ENOG4105C0B	DNA polymerase III (alpha subunit)
A4V05_09095	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
A4V05_09100	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A4V05_09120	ENOG4105C37	(CBS) domain
A4V05_09125	ENOG4105C37	(CBS) domain
A4V05_09135	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A4V05_09140	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A4V05_09145	ENOG4108UW5	maltose o-acetyltransferase
A4V05_09170	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A4V05_09175	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A4V05_09195	ENOG4106855	Competence protein
A4V05_09210	ENOG4105E2D	ec 3.2.1.52
A4V05_09215	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A4V05_09235	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A4V05_09240	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A4V05_09250	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A4V05_09275	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
A4V05_09280	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
A4V05_09285	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
A4V05_09290	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A4V05_09300	ENOG4108775	30S ribosomal protein S21
A4V05_09305	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
A4V05_09320	ENOG4105C54	Major Facilitator superfamily
A4V05_09335	ENOG4105CX6	glutaminyL-tRNA synthetase
A4V05_09340	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A4V05_09345	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A4V05_09350	ENOG410803B	Involved in the transcription termination process (By similarity)
A4V05_09355	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A4V05_09360	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A4V05_09365	ENOG4105CDU	Replicative dna helicase
A4V05_09380	ENOG4105CEV	competence damage-inducible protein
A4V05_09390	ENOG4108W0I	acetyltransferase
A4V05_09415	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A4V05_09420	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A4V05_09425	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A4V05_09430	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A4V05_09445	ENOG4105C79	DNA protecting protein DprA
A4V05_09450	ENOG4105DZ1	carboxypeptidase
A4V05_09455	ENOG4105C3G	gtp-binding protein
A4V05_09460	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A4V05_09470	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A4V05_09485	ENOG41061MV	Arylsulfatase
A4V05_09510	ENOG4105NQG	DoxX
A4V05_09515	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A4V05_09520	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A4V05_09525	ENOG4105EMN	RNA polymerase sigma factor
A4V05_09545	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A4V05_09570	ENOG4107EDW	L-fucose operon activator
A4V05_09580	ENOG4105C3J	Cysteine desulfurase
A4V05_09590	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A4V05_09605	ENOG4106H78	methyltransferase
A4V05_09620	ENOG4105CSR	polyphosphate kinase 2
A4V05_09635	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
A4V05_09645	ENOG4107XM9	(LipO)protein
A4V05_09650	ENOG4105K8N	protein family UPF0079, ATPase
A4V05_09655	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
A4V05_09660	ENOG4105K46	50S ribosomal protein l27
A4V05_09665	ENOG4105G5W	regulator Fur family
A4V05_09670	ENOG4105C3K	feS assembly ATPase SufC
A4V05_09675	ENOG4105DIW	FeS assembly protein SUFB
A4V05_09680	ENOG4105JRK	feS assembly protein SufD
A4V05_09690	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A4V05_09695	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A4V05_09735	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A4V05_09755	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A4V05_09760	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A4V05_09765	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
A4V05_09770	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
A4V05_09775	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A4V05_09790	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
A4V05_09800	ENOG4105CJN	penicillin-binding protein
A4V05_09860	ENOG4105D06	uba thif-type nad fad binding protein
A4V05_09865	ENOG4105C2X	Arabinose 5-phosphate isomerase
A4V05_09885	ENOG4105D7W	serine acetyltransferase
A4V05_09890	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
A4V05_09895	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A4V05_09905	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A4V05_09910	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
A4V05_09915	ENOG4107QPR	SAICAR synthetase
A4V05_09925	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A4V05_09930	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A4V05_09940	ENOG4105CN9	Peptidase m42 family protein
A4V05_09960	ENOG4105DFF	Rod shape-determining protein mreb
A4V05_09965	ENOG4105C03	ribonuclease
A4V05_09995	ENOG4109015	Biopolymer transport protein exbD tolR
A4V05_10010	ENOG4105CSM	endonuclease III
A4V05_10030	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A4V05_10035	ENOG41080R2	UPF0102 protein
A4V05_10045	ENOG4105C37	(CBS) domain
A4V05_10055	ENOG41082R9	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
A4V05_10070	ENOG4105CDH	Citrulline--aspartate ligase
A4V05_10075	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A4V05_10085	ENOG4105CP7	Triose-phosphate isomerase
A4V05_10100	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
A4V05_10120	ENOG41081UC	Inherit from COG: Competence protein
A4V05_10130	ENOG4105DXN	mazG family
A4V05_10155	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
A4V05_10165	ENOG4107RAN	Peptidase, M16
A4V05_10185	ENOG4105WPN	DNA integration recombination invertion protein
A4V05_10190	ENOG4107R11	Transcriptional regulator
A4V05_10195	ENOG4105SYT	Methylenetetrahydrofolate reductase
A4V05_10210	ENOG4105DGA	Diaminopimelate dehydrogenase
A4V05_10215	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
A4V05_10235	ENOG4105C7B	Threonine dehydratase
A4V05_10240	ENOG4108Z03	MAF-like protein
A4V05_10245	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A4V05_10250	ENOG4105D9P	serine threonine protein kinase
A4V05_10265	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A4V05_10275	ENOG4105CAT	Cytidine monophosphate kinase
A4V05_10285	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A4V05_10295	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A4V05_10305	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A4V05_10335	ENOG4105CGK	Exodeoxyribonuclease III
A4V05_10340	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A4V05_10355	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A4V05_10360	ENOG4107QRG	dna polymerase iii
A4V05_10390	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
A4V05_10410	ENOG4105W5A	BNR Asp-box repeat protein
A4V05_10435	ENOG4105D9P	serine threonine protein kinase
A4V05_10450	ENOG4105KAF	membrAne
A4V05_10480	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A4V05_10485	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A4V05_10490	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
A4V05_10495	ENOG4105K64	Glycosyl transferase, family 2
A4V05_10500	ENOG4105K64	Glycosyl transferase, family 2
A4V05_10525	ENOG4107TAE	Glycosyl transferase (Group 1
A4V05_10545	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
A4V05_10550	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A4V05_10555	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
A4V05_10565	ENOG4105EN6	Membrane
A4V05_10570	ENOG4105CY0	Metallo-Beta-Lactamase
A4V05_10575	ENOG4108V6E	Cell division protein mraZ
A4V05_10580	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A4V05_10590	ENOG4105CJN	penicillin-binding protein
A4V05_10595	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A4V05_10600	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
A4V05_10605	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A4V05_10610	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A4V05_10620	ENOG4105CNI	cell division protein FtsW
A4V05_10625	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
A4V05_10630	ENOG4105DFU	Cell wall formation (By similarity)
A4V05_10635	ENOG4105CPF	Cell wall formation (By similarity)
A4V05_10645	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A4V05_10650	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
A4V05_10655	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A4V05_10660	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4V05_10665	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
A4V05_10675	ENOG4105C0H	protease
A4V05_10685	ENOG4105D49	3-dehydroquinate synthase
A4V05_10695	ENOG4108JQ7	(ABC) transporter
A4V05_10705	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
A4V05_10710	ENOG4105CE9	30S ribosomal protein S2
A4V05_10720	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A4V05_10735	ENOG4108IUZ	ABC transporter
A4V05_10745	ENOG4105DFU	Cell wall formation (By similarity)
A4V05_10750	ENOG4105UYK	outer membrane protein a
A4V05_10760	ENOG4105KVH	Transcriptional regulator
A4V05_10770	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
A4V05_10785	ENOG4105C5S	asparaginyl-tRNA synthetase
A4V05_10795	ENOG4105K63	Thioredoxin
A4V05_10845	ENOG4105DUM	transcriptional regulator, lysR family
A4V05_10850	ENOG4105HMI	Membrane
A4V05_10855	ENOG4107STF	Involved in phosphonate degradation (By similarity)
A4V05_10880	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A4V05_10885	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A4V05_10890	ENOG4105CDY	transcriptional regulatory protein
A4V05_10900	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A4V05_10910	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
A4V05_10915	ENOG4105DI5	UPF0365 protein
A4V05_10925	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A4V05_10930	ENOG4107RY6	amino acid
A4V05_10940	ENOG4105DSF	transport protein
A4V05_10945	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A4V05_10950	ENOG4107RCW	fructose-bisphosphate aldolase
A4V05_10955	ENOG4105CI3	gtp-binding protein typa
A4V05_10960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A4V05_10985	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A4V05_11045	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A4V05_11050	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A4V05_11060	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A4V05_11075	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A4V05_11080	ENOG4105X0D	Fimbrial protein
A4V05_11090	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
A4V05_11100	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A4V05_11115	ENOG4105DIN	metallophosphoesterase
A4V05_11135	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
A4V05_11140	ENOG4105K64	Glycosyl transferase, family 2
A4V05_11165	ENOG4105EXC	Acyl-transferase
A4V05_11180	ENOG4107QWE	)-transporter
A4V05_11225	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A4V05_11230	ENOG4105C5I	Dehydrogenase
A4V05_11240	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A4V05_11245	ENOG4105NAU	thioesterase Superfamily protein
A4V05_11255	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A4V05_11265	ENOG4105KK6	nuclease
A4V05_11280	ENOG4105GTN	ParB Domain Protein Nuclease
A4V05_11285	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
A4V05_11300	ENOG4105F5P	DNA-damage-inducible protein d
A4V05_11430	ENOG4105CDU	Replicative dna helicase
A4V05_11515	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A4V05_11530	ENOG4105C0P	Mg chelatase subunit ChlI
A4V05_11550	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A4V05_11565	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
A4V05_11570	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
A4V05_11580	ENOG4105CRK	lysyL-tRNA synthetase
A4V05_11590	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A4V05_11600	ENOG4105KVH	Transcriptional regulator
A4V05_11610	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A4V05_11630	ENOG4105CQ7	ATP-dependent helicase
A4V05_11635	ENOG4108ZP8	Acetolactate synthase small subunit
A4V05_11640	ENOG4105C0H	protease
A4V05_11655	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
A4V05_11665	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A4V05_11670	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A4V05_11680	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A4V05_11710	ENOG4105F8V	Hydrolase, tatD family
A4V05_11720	ENOG4105CNT	hydrolase family 2
A4V05_11740	ENOG4105C08	Histidine kinase
A4V05_11745	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A4V05_11755	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A4V05_11760	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
A4V05_11765	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
A4V05_11785	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A4V05_11830	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
A4V05_11840	ENOG4105CHH	sulfate transporter
A4V05_11845	ENOG4105CH7	arginosuccinase
A4V05_11860	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A4V05_11865	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A4V05_11875	ENOG4105EQI	Metal Dependent Phosphohydrolase
A4V05_11885	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A4V05_11890	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A4V05_11910	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A4V05_11915	ENOG4105DME	alpha-galactosidase
A4V05_11920	ENOG4105D0C	transport protein
A4V05_11935	ENOG4105C8P	)-transporter
A4V05_11970	ENOG4108RAC	Rubrerythrin
A4V05_11980	ENOG4105CN9	Peptidase m42 family protein
A4V05_11985	ENOG4105E2D	ec 3.2.1.52
A4V05_11995	ENOG4105G6Z	alkaline phosphatase
A4V05_12000	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
A4V05_12005	ENOG4105C8Y	Acetylornithine aminotransferase
A4V05_12015	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A4V05_12025	ENOG4105C59	p-type ATPase
A4V05_12030	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A4V05_12035	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A4V05_12040	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A4V05_12075	ENOG4105CPP	Dehydrogenase, E1 component
A4V05_12080	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
A4V05_12090	ENOG4108Z6Z	Transcriptional regulator
A4V05_12095	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A4V05_12100	ENOG4105BZS	acriflavin resistance protein
A4V05_12125	ENOG4105C6E	dna polymerase iii
A4V05_12145	ENOG4105E5Q	amino acid AbC transporter
A4V05_12205	ENOG4105D9Q	decarboxylase (Beta subunit)
A4V05_12215	ENOG4105FE9	pseudouridine synthase
A4V05_12225	ENOG4105CSR	polyphosphate kinase 2