locus-tag	class	description
FMZ60_00025	COG0494	nUDIX hydrolase
FMZ60_00030	COG1304	FMN binding
FMZ60_00050	COG1476	TRANSCRIPTIONal
FMZ60_00060	COG0477	Major facilitator Superfamily
FMZ60_00065	COG2353	YceI-like domain
FMZ60_00075	COG3038	cytochrome b561
FMZ60_00080	COG3391	amine dehydrogenase activity
FMZ60_00090	COG3618	amidohydrolase
FMZ60_00100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FMZ60_00105	COG1522	sequence-specific DNA binding
FMZ60_00110	COG0028	Belongs to the TPP enzyme family
FMZ60_00115	COG1811	Na channel or pump
FMZ60_00125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FMZ60_00130	COG2922	Belongs to the Smg family
FMZ60_00135	COG0025	NhaP-type Na H and K H
FMZ60_00145	COG4771	TonB-dependent receptor
FMZ60_00160	COG2853	Lipoprotein
FMZ60_00165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FMZ60_00170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FMZ60_00175	COG1127	ABC transporter
FMZ60_00185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FMZ60_00195	COG0018	arginyl-trna synthetase
FMZ60_00230	COG3706	GGDEF domain
FMZ60_00230	COG0745	RESPONSE REGULATOR receiver
FMZ60_00240	COG0625	glutathione transferase activity
FMZ60_00245	COG2857	Cytochrome c1
FMZ60_00250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FMZ60_00255	COG0723	plastoquinol--plastocyanin reductase activity
FMZ60_00260	COG1970	mechanosensitive ion channel activity
FMZ60_00265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FMZ60_00285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FMZ60_00290	COG0537	adenosine 5'-monophosphoramidase activity
FMZ60_00295	COG0140	phosphoribosyl-ATP diphosphatase activity
FMZ60_00300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FMZ60_00305	COG0107	imidazoleglycerol-phosphate synthase activity
FMZ60_00310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FMZ60_00315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FMZ60_00320	COG0131	Imidazoleglycerol-phosphate dehydratase
FMZ60_00325	COG0730	response to heat
FMZ60_00330	COG1309	transcriptional regulator
FMZ60_00335	COG0019	diaminopimelate decarboxylase activity
FMZ60_00345	COG2860	membrane
FMZ60_00355	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FMZ60_00360	COG1088	dTDP-glucose 4,6-dehydratase activity
FMZ60_00365	COG3300	MHYT domain
FMZ60_00365	COG5001	Diguanylate cyclase
FMZ60_00370	COG2205	protein histidine kinase activity
FMZ60_00370	COG0784	Response regulator, receiver
FMZ60_00375	COG2197	response regulator
FMZ60_00380	COG0784	Response regulator, receiver
FMZ60_00380	COG2205	protein histidine kinase activity
FMZ60_00390	COG2197	response regulator
FMZ60_00420	COG3121	Chaperone
FMZ60_00440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FMZ60_00455	COG2207	Transcriptional regulator
FMZ60_00490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FMZ60_00505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FMZ60_00510	COG0367	asparagine synthase
FMZ60_00530	COG0107	imidazoleglycerol-phosphate synthase activity
FMZ60_00540	COG1083	cytidylyl-transferase
FMZ60_00545	COG2089	acid synthase
FMZ60_00550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FMZ60_00560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FMZ60_00575	COG1696	Membrane protein involved in D-alanine export
FMZ60_00610	COG2205	protein histidine kinase activity
FMZ60_00620	COG1956	GAF domain-containing protein
FMZ60_00640	COG2814	Major facilitator Superfamily
FMZ60_00645	COG2233	PERMEase
FMZ60_00650	COG3243	poly(R)-hydroxyalkanoic acid synthase
FMZ60_00660	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_00665	COG0280	phosphate acetyltransferase
FMZ60_00670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FMZ60_00690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FMZ60_00695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FMZ60_00700	COG4988	ABC transporter
FMZ60_00715	COG1294	oxidase, subunit
FMZ60_00730	COG0840	transmembrane signaling receptor activity
FMZ60_00735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_00740	COG0765	amino acid transport
FMZ60_00745	COG0765	amino acid transport
FMZ60_00750	COG1126	abc transporter atp-binding protein
FMZ60_00765	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FMZ60_00770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FMZ60_00775	COG2890	protein-(glutamine-N5) methyltransferase activity
FMZ60_00780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FMZ60_00795	COG0513	Belongs to the DEAD box helicase family
FMZ60_00800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FMZ60_00815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FMZ60_00865	COG4964	Belongs to the GSP D family
FMZ60_00905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FMZ60_00940	COG0745	RESPONSE REGULATOR receiver
FMZ60_00945	COG2205	protein histidine kinase activity
FMZ60_00960	COG2918	glutathione biosynthetic process
FMZ60_00965	COG2197	response regulator
FMZ60_00970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FMZ60_00975	COG2813	Specifically methylates the guanine in position
FMZ60_00975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FMZ60_00980	COG2223	nitrite transmembrane transporter activity
FMZ60_00995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FMZ60_01000	COG0708	Exodeoxyribonuclease III
FMZ60_01005	COG0753	catalase activity
FMZ60_01025	COG2252	PERMEase
FMZ60_01030	COG0166	Belongs to the GPI family
FMZ60_01035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FMZ60_01040	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FMZ60_01050	COG0557	exoribonuclease II activity
FMZ60_01055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FMZ60_01075	COG2264	protein methyltransferase activity
FMZ60_01080	COG0439	Biotin carboxylase
FMZ60_01085	COG0511	ligase activity, forming carbon-carbon bonds
FMZ60_01090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FMZ60_01095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FMZ60_01100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FMZ60_01105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMZ60_01120	COG0823	Involved in the tonB-independent uptake of proteins
FMZ60_01130	COG0848	biopolymer transport protein
FMZ60_01140	COG0824	Thioesterase
FMZ60_01150	COG0494	nUDIX hydrolase
FMZ60_01180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FMZ60_01235	COG2001	Belongs to the MraZ family
FMZ60_01240	COG0275	rRNA processing
FMZ60_01245	COG3116	cell division
FMZ60_01255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FMZ60_01260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FMZ60_01265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FMZ60_01275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FMZ60_01280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FMZ60_01285	COG1181	Belongs to the D-alanine--D-alanine ligase family
FMZ60_01290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FMZ60_01300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FMZ60_01305	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FMZ60_01315	COG0739	heme binding
FMZ60_01320	COG0653	protein targeting
FMZ60_01325	COG0840	transmembrane signaling receptor activity
FMZ60_01335	COG2239	Acts as a magnesium transporter
FMZ60_01340	COG1607	acyl-coa hydrolase
FMZ60_01375	COG1473	amidohydrolase
FMZ60_01385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FMZ60_01385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_01395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMZ60_01400	COG2011	ABC-type metal ion transport system permease component
FMZ60_01415	COG0513	Belongs to the DEAD box helicase family
FMZ60_01420	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_01425	COG4689	acetoacetate decarboxylase
FMZ60_01435	COG0477	Major facilitator Superfamily
FMZ60_01440	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_01445	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FMZ60_01465	COG1473	amidohydrolase
FMZ60_01475	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FMZ60_01480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FMZ60_01500	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_01505	COG1454	alcohol dehydrogenase
FMZ60_01530	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FMZ60_01575	COG4585	Histidine kinase
FMZ60_01590	COG3188	usher protein
FMZ60_01595	COG3121	Chaperone
FMZ60_01605	COG5001	Diguanylate cyclase
FMZ60_01605	COG3300	MHYT domain
FMZ60_01615	COG0668	transmembrane transport
FMZ60_01625	COG0559	Belongs to the binding-protein-dependent transport system permease family
FMZ60_01630	COG1172	Belongs to the binding-protein-dependent transport system permease family
FMZ60_01635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMZ60_01640	COG0410	ABC transporter
FMZ60_01645	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_01675	COG1674	ftsk spoiiie
FMZ60_01705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FMZ60_01715	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FMZ60_01735	COG1595	DNA-templated transcription, initiation
FMZ60_01740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_01745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_01750	COG1522	sequence-specific DNA binding
FMZ60_01770	COG1301	dicarboxylic acid transport
FMZ60_01775	COG4191	Histidine kinase
FMZ60_01785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_01790	COG2200	EAL domain
FMZ60_01805	COG0243	molybdopterin cofactor binding
FMZ60_01805	COG3383	formate dehydrogenase (NAD+) activity
FMZ60_01810	COG0437	4 iron, 4 sulfur cluster binding
FMZ60_01815	COG2864	formate dehydrogenase
FMZ60_01830	COG0842	Transport permease protein
FMZ60_01835	COG1129	ABC transporter
FMZ60_01835	COG0842	Transport permease protein
FMZ60_01840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMZ60_01855	COG2423	ornithine cyclodeaminase activity
FMZ60_01860	COG1522	sequence-specific DNA binding
FMZ60_01870	COG0833	amino acid
FMZ60_01875	COG1522	sequence-specific DNA binding
FMZ60_01880	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FMZ60_01880	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FMZ60_01880	COG0506	proline dehydrogenase activity
FMZ60_01885	COG2199	diguanylate cyclase activity
FMZ60_01885	COG2203	Gaf domain
FMZ60_01890	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FMZ60_01905	COG0583	DNA-binding transcription factor activity
FMZ60_01920	COG0598	Magnesium transport protein CorA
FMZ60_01935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FMZ60_01940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FMZ60_01945	COG2822	iron ion transport
FMZ60_01965	COG4566	intracellular signal transduction
FMZ60_01975	COG1285	pathogenesis
FMZ60_01980	COG2239	Acts as a magnesium transporter
FMZ60_01985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FMZ60_02030	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FMZ60_02035	COG1278	Cold shock
FMZ60_02040	COG1566	PFAM secretion protein HlyD family protein
FMZ60_02050	COG1136	(ABC) transporter
FMZ60_02060	COG0243	molybdopterin cofactor binding
FMZ60_02065	COG1454	alcohol dehydrogenase
FMZ60_02100	COG1414	Transcriptional regulator
FMZ60_02105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FMZ60_02110	COG1116	anion transmembrane transporter activity
FMZ60_02115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FMZ60_02125	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_02130	COG0640	Transcriptional regulator
FMZ60_02135	COG1902	pentaerythritol trinitrate reductase activity
FMZ60_02165	COG2814	Major facilitator Superfamily
FMZ60_02180	COG3290	protein histidine kinase activity
FMZ60_02180	COG0840	transmembrane signaling receptor activity
FMZ60_02195	COG0840	transmembrane signaling receptor activity
FMZ60_02225	COG0395	ABC-type sugar transport system, permease component
FMZ60_02235	COG1653	transport
FMZ60_02240	COG3842	ATPase activity
FMZ60_02245	COG1349	DNA-binding transcription factor activity
FMZ60_02250	COG0450	alkyl hydroperoxide reductase
FMZ60_02255	COG3634	alkyl hydroperoxide reductase activity
FMZ60_02275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FMZ60_02285	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FMZ60_02300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FMZ60_02305	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FMZ60_02310	COG0193	aminoacyl-tRNA hydrolase activity
FMZ60_02320	COG0012	GTP binding
FMZ60_02330	COG1595	DNA-templated transcription, initiation
FMZ60_02335	COG3712	iron ion homeostasis
FMZ60_02340	COG4774	siderophore transport
FMZ60_02345	COG0488	(ABC) transporter
FMZ60_02375	COG2837	iron assimilation
FMZ60_02380	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FMZ60_02385	COG1090	epimerase
FMZ60_02390	COG0415	Belongs to the DNA photolyase family
FMZ60_02395	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_02405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_02410	COG1126	abc transporter atp-binding protein
FMZ60_02415	COG2188	Transcriptional regulator
FMZ60_02425	COG0583	DNA-binding transcription factor activity
FMZ60_02435	COG0540	Belongs to the ATCase OTCase family
FMZ60_02445	COG2153	protein acetylation
FMZ60_02460	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FMZ60_02465	COG0795	lipopolysaccharide-transporting ATPase activity
FMZ60_02470	COG0583	DNA-binding transcription factor activity
FMZ60_02480	COG0791	NLP P60 protein
FMZ60_02485	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FMZ60_02495	COG0840	transmembrane signaling receptor activity
FMZ60_02500	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FMZ60_02510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FMZ60_02530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FMZ60_02545	COG0495	leucyl-tRNA aminoacylation
FMZ60_02555	COG0840	transmembrane signaling receptor activity
FMZ60_02580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FMZ60_02585	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FMZ60_02590	COG3706	GGDEF domain
FMZ60_02610	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FMZ60_02615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FMZ60_02620	COG2391	methyltransferase activity
FMZ60_02625	COG2897	thiosulfate sulfurtransferase activity
FMZ60_02640	COG4176	ABC-type proline glycine betaine transport system permease component
FMZ60_02645	COG4175	Glycine betaine
FMZ60_02645	COG3448	diguanylate cyclase activity
FMZ60_02665	COG2984	ABC transporter substrate binding protein
FMZ60_02680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMZ60_02685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FMZ60_02690	COG1538	Outer membrane efflux protein
FMZ60_02695	COG0736	holo-[acyl-carrier-protein] synthase activity
FMZ60_02700	COG1472	Belongs to the glycosyl hydrolase 3 family
FMZ60_02705	COG0322	excinuclease ABC activity
FMZ60_02710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FMZ60_02730	COG1253	flavin adenine dinucleotide binding
FMZ60_02735	COG1968	undecaprenyl-diphosphatase activity
FMZ60_02740	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FMZ60_02745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FMZ60_02755	COG0215	cysteine-tRNA ligase activity
FMZ60_02765	COG0825	malonyl-CoA metabolic process
FMZ60_02770	COG0037	tRNA processing
FMZ60_02775	COG0527	aspartate kinase activity
FMZ60_02790	COG1335	isochorismatase
FMZ60_02845	COG3384	dioxygenase
FMZ60_02850	COG0583	DNA-binding transcription factor activity
FMZ60_02855	COG0840	transmembrane signaling receptor activity
FMZ60_02860	COG0840	transmembrane signaling receptor activity
FMZ60_02865	COG0730	response to heat
FMZ60_02880	COG0109	protoheme IX farnesyltransferase activity
FMZ60_02885	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FMZ60_02890	COG1845	cytochrome c oxidase, subunit III
FMZ60_02900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FMZ60_02930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FMZ60_02945	COG0583	DNA-binding transcription factor activity
FMZ60_02965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FMZ60_02980	COG1652	LysM domain
FMZ60_02985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FMZ60_03035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FMZ60_03050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FMZ60_03055	COG1408	metallophosphoesterase
FMZ60_03060	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_03065	COG1064	alcohol dehydrogenase
FMZ60_03070	COG0247	lactate metabolic process
FMZ60_03075	COG0277	FAD linked oxidase domain protein
FMZ60_03080	COG0277	FAD linked oxidase domain protein
FMZ60_03085	COG2186	Transcriptional regulator
FMZ60_03090	COG0583	DNA-binding transcription factor activity
FMZ60_03095	COG4948	Mandelate Racemase Muconate Lactonizing
FMZ60_03100	COG2995	paraquat-inducible protein a
FMZ60_03105	COG2995	paraquat-inducible protein a
FMZ60_03110	COG3008	intermembrane lipid transfer
FMZ60_03110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FMZ60_03125	COG0076	glutamate decarboxylase activity
FMZ60_03130	COG0840	transmembrane signaling receptor activity
FMZ60_03145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FMZ60_03155	COG3210	domain, Protein
FMZ60_03180	COG0835	chemotaxis
FMZ60_03180	COG0784	Response regulator, receiver
FMZ60_03205	COG3023	N-Acetylmuramoyl-L-alanine amidase
FMZ60_03210	COG1346	cytolysis
FMZ60_03215	COG1380	Effector of murein hydrolase LrgA
FMZ60_03220	COG0436	Aminotransferase
FMZ60_03230	COG0280	phosphate acetyltransferase
FMZ60_03230	COG0281	malic enzyme
FMZ60_03255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FMZ60_03260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FMZ60_03265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FMZ60_03270	COG0126	phosphoglycerate kinase activity
FMZ60_03280	COG1294	oxidase, subunit
FMZ60_03285	COG1271	oxidase subunit
FMZ60_03295	COG0028	Belongs to the TPP enzyme family
FMZ60_03305	COG0071	Belongs to the small heat shock protein (HSP20) family
FMZ60_03320	COG0306	phosphate transporter
FMZ60_03325	COG0747	negative chemotaxis
FMZ60_03335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMZ60_03340	COG4172	Belongs to the ABC transporter superfamily
FMZ60_03350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_03355	COG4206	TonB-dependent receptor
FMZ60_03355	COG1629	transport
FMZ60_03360	COG3712	iron ion homeostasis
FMZ60_03365	COG1595	DNA-templated transcription, initiation
FMZ60_03390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FMZ60_03395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FMZ60_03400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FMZ60_03405	COG0009	L-threonylcarbamoyladenylate synthase
FMZ60_03415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMZ60_03420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FMZ60_03425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FMZ60_03465	COG0259	pyridoxamine-phosphate oxidase activity
FMZ60_03475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FMZ60_03490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FMZ60_03500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FMZ60_03545	COG0039	L-malate dehydrogenase activity
FMZ60_03550	COG2188	Transcriptional regulator
FMZ60_03555	COG2009	succinate dehydrogenase
FMZ60_03565	COG1053	succinate dehydrogenase
FMZ60_03570	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FMZ60_03575	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FMZ60_03580	COG0372	Belongs to the citrate synthase family
FMZ60_03585	COG0567	Dehydrogenase, E1 component
FMZ60_03590	COG0508	dehydrogenase complex catalyzes the overall conversion of
FMZ60_03595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FMZ60_03605	COG4771	TonB-dependent receptor
FMZ60_03615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FMZ60_03620	COG2363	Small membrane protein
FMZ60_03625	COG0180	Tryptophanyl-tRNA synthetase
FMZ60_03630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FMZ60_03640	COG2999	glutathione oxidoreductase activity
FMZ60_03645	COG2183	response to ionizing radiation
FMZ60_03650	COG1199	ATP-dependent helicase activity
FMZ60_03660	COG0564	pseudouridine synthase activity
FMZ60_03670	COG3243	poly(R)-hydroxyalkanoic acid synthase
FMZ60_03675	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_03680	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FMZ60_03685	COG5487	UPF0391 membrane protein
FMZ60_03690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FMZ60_03695	COG2070	2-Nitropropane dioxygenase
FMZ60_03700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FMZ60_03705	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FMZ60_03715	COG2096	Adenosyltransferase
FMZ60_03720	COG1113	amino acid transport
FMZ60_03775	COG3501	Rhs element vgr protein
FMZ60_03830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FMZ60_03845	COG4566	intracellular signal transduction
FMZ60_03850	COG2962	Rard protein
FMZ60_03855	COG1522	sequence-specific DNA binding
FMZ60_03860	COG3258	Cytochrome c
FMZ60_03880	COG0557	exoribonuclease II activity
FMZ60_03885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FMZ60_03895	COG0776	regulation of translation
FMZ60_03905	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FMZ60_03910	COG1185	polyribonucleotide nucleotidyltransferase activity
FMZ60_03915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FMZ60_03920	COG1595	DNA-templated transcription, initiation
FMZ60_03935	COG0277	FAD linked oxidase domain protein
FMZ60_03965	COG3237	CsbD-like
FMZ60_03995	COG0149	triose-phosphate isomerase activity
FMZ60_04020	COG1923	regulation of RNA biosynthetic process
FMZ60_04025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FMZ60_04030	COG0330	HflC and HflK could
FMZ60_04035	COG0330	HflC and HflK could
FMZ60_04040	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FMZ60_04045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FMZ60_04050	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FMZ60_04055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FMZ60_04095	COG0488	(ABC) transporter
FMZ60_04100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FMZ60_04125	COG1683	Conserved Protein
FMZ60_04130	COG2199	diguanylate cyclase activity
FMZ60_04135	COG1289	transmembrane transporter activity
FMZ60_04145	COG3022	response to hydroperoxide
FMZ60_04150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FMZ60_04155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FMZ60_04160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FMZ60_04165	COG3958	Transketolase
FMZ60_04170	COG3959	Transketolase, thiamine diphosphate binding domain
FMZ60_04175	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_04180	COG0583	DNA-binding transcription factor activity
FMZ60_04185	COG2255	four-way junction helicase activity
FMZ60_04205	COG1280	lysine exporter protein (LysE YggA)
FMZ60_04210	COG1408	metallophosphoesterase
FMZ60_04215	COG4681	YaeQ
FMZ60_04220	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FMZ60_04230	COG3706	GGDEF domain
FMZ60_04240	COG2824	Alkylphosphonate utilization operon protein PhnA
FMZ60_04245	COG0252	asparaginase activity
FMZ60_04260	COG0765	amino acid transport
FMZ60_04280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FMZ60_04290	COG0697	spore germination
FMZ60_04295	COG1595	DNA-templated transcription, initiation
FMZ60_04335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FMZ60_04355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FMZ60_04360	COG4206	TonB-dependent receptor
FMZ60_04390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FMZ60_04405	COG3300	MHYT domain
FMZ60_04405	COG5001	Diguanylate cyclase
FMZ60_04420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FMZ60_04425	COG3383	formate dehydrogenase (NAD+) activity
FMZ60_04445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FMZ60_04465	COG0259	pyridoxamine-phosphate oxidase activity
FMZ60_04550	COG0303	'Molybdopterin
FMZ60_04555	COG0314	molybdopterin synthase activity
FMZ60_04560	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FMZ60_04565	COG0315	cyclic pyranopterin monophosphate synthase activity
FMZ60_04575	COG0697	spore germination
FMZ60_04580	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FMZ60_04585	COG1764	response to oxidative stress
FMZ60_04590	COG4149	molybdate abc transporter
FMZ60_04595	COG0725	ABC transporter, periplasmic molybdate-binding protein
FMZ60_04620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FMZ60_04625	COG0433	COG0433 Predicted ATPase
FMZ60_04645	COG0697	spore germination
FMZ60_04655	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FMZ60_04660	COG0308	aminopeptidase N
FMZ60_04675	COG0312	modulator of DNA gyrase
FMZ60_04680	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FMZ60_04685	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_04700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FMZ60_04705	COG1702	phosphate starvation-inducible protein PhoH
FMZ60_04710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FMZ60_04715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FMZ60_04725	COG1862	Preprotein translocase
FMZ60_04730	COG0343	queuine tRNA-ribosyltransferase activity
FMZ60_04735	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FMZ60_04740	COG2027	D-alanyl-D-alanine carboxypeptidase
FMZ60_04750	COG1648	precorrin-2 dehydrogenase activity
FMZ60_04750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FMZ60_04770	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FMZ60_04775	COG0741	lytic transglycosylase activity
FMZ60_04780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FMZ60_04790	COG0316	Belongs to the HesB IscA family
FMZ60_04795	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FMZ60_04800	COG0739	heme binding
FMZ60_04805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FMZ60_04810	COG1881	PFAM PEBP family protein
FMZ60_04815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FMZ60_04820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FMZ60_04825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FMZ60_04825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FMZ60_04835	COG1832	CoA-binding protein
FMZ60_04845	COG1278	Cold shock
FMZ60_04850	COG0427	acetyl-CoA hydrolase
FMZ60_04855	COG0583	DNA-binding transcription factor activity
FMZ60_04880	COG1271	oxidase subunit
FMZ60_04885	COG1294	oxidase, subunit
FMZ60_04925	COG2207	Transcriptional regulator
FMZ60_04930	COG4221	oxidoreductase activity
FMZ60_04935	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_04980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FMZ60_04995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FMZ60_05020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FMZ60_05025	COG0425	Belongs to the sulfur carrier protein TusA family
FMZ60_05035	COG0612	Peptidase, M16
FMZ60_05040	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FMZ60_05045	COG2894	cell division
FMZ60_05050	COG0850	regulation of cytokinetic process
FMZ60_05055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FMZ60_05070	COG0514	ATP-dependent DNA helicase (RecQ)
FMZ60_05080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_05085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FMZ60_05090	COG0735	belongs to the Fur family
FMZ60_05105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FMZ60_05115	COG3178	'Phosphotransferase
FMZ60_05125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FMZ60_05130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FMZ60_05135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FMZ60_05145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FMZ60_05155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FMZ60_05160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FMZ60_05175	COG0438	transferase activity, transferring glycosyl groups
FMZ60_05185	COG0438	transferase activity, transferring glycosyl groups
FMZ60_05200	COG0429	hydrolase of the alpha beta-hydrolase fold
FMZ60_05220	COG0513	Belongs to the DEAD box helicase family
FMZ60_05235	COG1546	Belongs to the CinA family
FMZ60_05235	COG1058	Belongs to the CinA family
FMZ60_05270	COG3135	benzoate transporter
FMZ60_05275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FMZ60_05280	COG0167	dihydroorotate dehydrogenase activity
FMZ60_05285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FMZ60_05290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FMZ60_05310	COG0762	integral membrane protein
FMZ60_05315	COG0024	Methionine aminopeptidase
FMZ60_05325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FMZ60_05340	COG3028	Belongs to the UPF0307 family
FMZ60_05345	COG0312	modulator of DNA gyrase
FMZ60_05350	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FMZ60_05355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FMZ60_05360	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FMZ60_05365	COG0300	oxidoreductase activity
FMZ60_05375	COG0741	lytic transglycosylase activity
FMZ60_05375	COG0739	heme binding
FMZ60_05375	COG1196	nuclear chromosome segregation
FMZ60_05405	COG2814	Major facilitator Superfamily
FMZ60_05420	COG1879	ABC-type sugar transport system periplasmic component
FMZ60_05465	COG0456	acetyltransferase
FMZ60_05480	COG1113	amino acid transport
FMZ60_05485	COG1169	isochorismate synthase
FMZ60_05490	COG3433	isochorismatase activity
FMZ60_05490	COG1535	isochorismatase
FMZ60_05495	COG1595	DNA-templated transcription, initiation
FMZ60_05505	COG4774	siderophore transport
FMZ60_05520	COG0251	oxidation-reduction process
FMZ60_05530	COG0129	dihydroxy-acid dehydratase activity
FMZ60_05540	COG2271	Major facilitator Superfamily
FMZ60_05545	COG4948	Mandelate Racemase Muconate Lactonizing
FMZ60_05555	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_05560	COG3604	Transcriptional regulator
FMZ60_05580	COG0318	PFAM AMP-dependent synthetase and ligase
FMZ60_05585	COG1960	acyl-CoA dehydrogenase activity
FMZ60_05595	COG1473	amidohydrolase
FMZ60_05615	COG0492	ferredoxin-NADP+ reductase activity
FMZ60_05620	COG1674	ftsk spoiiie
FMZ60_05625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FMZ60_05630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FMZ60_05635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FMZ60_05640	COG1183	phosphatidylcholine synthase activity
FMZ60_05655	COG1196	nuclear chromosome segregation
FMZ60_05655	COG3264	Mechanosensitive ion channel
FMZ60_05665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FMZ60_05670	COG0586	Pfam SNARE associated Golgi protein
FMZ60_05685	COG0560	Phosphoserine phosphatase
FMZ60_05690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FMZ60_05695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FMZ60_05700	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FMZ60_05705	COG2205	protein histidine kinase activity
FMZ60_05710	COG0745	RESPONSE REGULATOR receiver
FMZ60_05720	COG1573	uracil-dna glycosylase
FMZ60_05725	COG2807	transmembrane transport
FMZ60_05730	COG2207	Transcriptional regulator
FMZ60_05735	COG2814	Major facilitator Superfamily
FMZ60_05740	COG1196	nuclear chromosome segregation
FMZ60_05750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FMZ60_05755	COG3550	peptidyl-serine autophosphorylation
FMZ60_05760	COG3620	sequence-specific DNA binding
FMZ60_05770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FMZ60_05785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FMZ60_05790	COG1122	ATPase activity
FMZ60_05800	COG1268	BioY protein
FMZ60_05830	COG0523	cobalamin synthesis protein
FMZ60_05835	COG0523	cobalamin synthesis protein
FMZ60_05840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FMZ60_05845	COG2878	Part of a membrane complex involved in electron transport
FMZ60_05860	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FMZ60_05865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FMZ60_05870	COG0133	tryptophan synthase activity
FMZ60_05875	COG0159	tryptophan synthase activity
FMZ60_05880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FMZ60_05885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FMZ60_05890	COG1530	ribonuclease E activity
FMZ60_05895	COG0564	pseudouridine synthase activity
FMZ60_05900	COG0546	phosphoglycolate phosphatase activity
FMZ60_05925	COG0424	maF-like protein
FMZ60_05935	COG3135	benzoate transporter
FMZ60_05940	COG1525	nuclease
FMZ60_05945	COG0747	negative chemotaxis
FMZ60_05950	COG0601	transmembrane transport
FMZ60_05955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMZ60_05960	COG4172	Belongs to the ABC transporter superfamily
FMZ60_05975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FMZ60_05985	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FMZ60_05995	COG0501	Belongs to the peptidase M48B family
FMZ60_06000	COG4269	membrane
FMZ60_06005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FMZ60_06040	COG0640	Transcriptional regulator
FMZ60_06045	COG1561	YicC-like family, N-terminal region
FMZ60_06065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FMZ60_06070	COG1187	pseudouridine synthase activity
FMZ60_06075	COG0779	Required for maturation of 30S ribosomal subunits
FMZ60_06080	COG0195	Participates in both transcription termination and antitermination
FMZ60_06080	COG2251	uridine kinase activity
FMZ60_06090	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FMZ60_06095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FMZ60_06110	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FMZ60_06115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FMZ60_06120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FMZ60_06125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FMZ60_06130	COG1388	LysM domain
FMZ60_06130	COG4942	peptidase
FMZ60_06140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FMZ60_06145	COG1758	RNA polymerase activity
FMZ60_06150	COG0194	GDP metabolic process
FMZ60_06155	COG0586	Pfam SNARE associated Golgi protein
FMZ60_06165	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FMZ60_06170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FMZ60_06175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FMZ60_06180	COG0196	riboflavin kinase activity
FMZ60_06185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FMZ60_06190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FMZ60_06190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FMZ60_06195	COG0583	DNA-binding transcription factor activity
FMZ60_06205	COG2814	Major facilitator Superfamily
FMZ60_06215	COG2807	transmembrane transport
FMZ60_06220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FMZ60_06230	COG0210	DNA helicase
FMZ60_06235	COG0488	(ABC) transporter
FMZ60_06240	COG2890	protein-(glutamine-N5) methyltransferase activity
FMZ60_06245	COG2171	N-acyltransferase activity
FMZ60_06260	COG0602	queuosine metabolic process
FMZ60_06265	COG0720	synthase
FMZ60_06275	COG2862	Uncharacterized protein family, UPF0114
FMZ60_06280	COG1422	Protein of unknown function (DUF1090)
FMZ60_06300	COG0544	peptidyl-prolyl cis-trans isomerase activity
FMZ60_06305	COG0740	serine-type endopeptidase activity
FMZ60_06310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FMZ60_06315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FMZ60_06320	COG0242	peptide deformylase activity
FMZ60_06325	COG2951	lytic endotransglycosylase activity
FMZ60_06330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FMZ60_06345	COG0165	Argininosuccinate lyase
FMZ60_06350	COG0668	transmembrane transport
FMZ60_06355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FMZ60_06355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FMZ60_06395	COG3161	chorismate lyase activity
FMZ60_06400	COG1187	pseudouridine synthase activity
FMZ60_06405	COG0584	glycerophosphoryl diester phosphodiesterase
FMZ60_06410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FMZ60_06420	COG4181	ATPase activity
FMZ60_06425	COG0285	dihydrofolate synthase activity
FMZ60_06435	COG1286	toxin biosynthetic process
FMZ60_06455	COG0024	Methionine aminopeptidase
FMZ60_06460	COG0052	Belongs to the universal ribosomal protein uS2 family
FMZ60_06465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FMZ60_06470	COG0528	UMP kinase activity
FMZ60_06475	COG0233	cytoplasmic translational termination
FMZ60_06480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FMZ60_06485	COG0575	Belongs to the CDS family
FMZ60_06490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FMZ60_06495	COG0750	zinc metalloprotease
FMZ60_06510	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FMZ60_06515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FMZ60_06520	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FMZ60_06525	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FMZ60_06530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FMZ60_06535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FMZ60_06550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FMZ60_06575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FMZ60_06580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FMZ60_06585	COG2867	negative regulation of translational initiation
FMZ60_06595	COG1024	Enoyl-CoA hydratase
FMZ60_06605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FMZ60_06610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FMZ60_06615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FMZ60_06620	COG0084	hydrolase, TatD family'
FMZ60_06630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FMZ60_06645	COG0625	glutathione transferase activity
FMZ60_06650	COG0386	Belongs to the glutathione peroxidase family
FMZ60_06685	COG0280	phosphate acetyltransferase
FMZ60_06685	COG0281	malic enzyme
FMZ60_06695	COG0410	ABC transporter
FMZ60_06710	COG0559	Belongs to the binding-protein-dependent transport system permease family
FMZ60_06725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FMZ60_06735	COG1175	transmembrane transport
FMZ60_06740	COG0395	ABC-type sugar transport system, permease component
FMZ60_06745	COG3842	ATPase activity
FMZ60_06760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FMZ60_06765	COG4208	sulfate ABC transporter
FMZ60_06775	COG0783	Belongs to the Dps family
FMZ60_06785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FMZ60_06800	COG1840	ABC-type Fe3 transport system, periplasmic component
FMZ60_06805	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FMZ60_06810	COG3842	ATPase activity
FMZ60_06820	COG2204	response regulator
FMZ60_06825	COG3852	Histidine kinase
FMZ60_06835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FMZ60_06840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FMZ60_06855	COG0789	Transcriptional regulator
FMZ60_06865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FMZ60_06870	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FMZ60_06885	COG1595	DNA-templated transcription, initiation
FMZ60_06895	COG4221	oxidoreductase activity
FMZ60_06900	COG2321	neutral zinc metallopeptidase
FMZ60_06915	COG1999	signal sequence binding
FMZ60_06930	COG2010	Cytochrome c
FMZ60_06950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FMZ60_06955	COG0840	transmembrane signaling receptor activity
FMZ60_06970	COG0704	Plays a role in the regulation of phosphate uptake
FMZ60_06975	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FMZ60_06980	COG1322	Protein conserved in bacteria
FMZ60_06985	COG1393	Belongs to the ArsC family
FMZ60_06990	COG1177	transmembrane transport
FMZ60_06995	COG1176	ABC-type spermidine putrescine transport system, permease component I
FMZ60_07000	COG3842	ATPase activity
FMZ60_07005	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FMZ60_07010	COG3642	lipopolysaccharide core region biosynthetic process
FMZ60_07020	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FMZ60_07025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FMZ60_07045	COG3712	iron ion homeostasis
FMZ60_07050	COG1595	DNA-templated transcription, initiation
FMZ60_07065	COG1562	ergosterol biosynthetic process
FMZ60_07090	COG3737	Protein of unknown function (DUF498/DUF598)
FMZ60_07095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FMZ60_07100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FMZ60_07105	COG0305	Participates in initiation and elongation during chromosome replication
FMZ60_07115	COG0359	binds to the 23S rRNA
FMZ60_07120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FMZ60_07130	COG0360	Binds together with S18 to 16S ribosomal RNA
FMZ60_07135	COG1469	GTP cyclohydrolase I activity
FMZ60_07140	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FMZ60_07145	COG0142	geranyltranstransferase activity
FMZ60_07150	COG1722	exodeoxyribonuclease VII activity
FMZ60_07170	COG0501	Belongs to the peptidase M48B family
FMZ60_07190	COG1611	Belongs to the LOG family
FMZ60_07195	COG0488	(ABC) transporter
FMZ60_07205	COG1619	proteins homologs of microcin C7 resistance protein MccF
FMZ60_07210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMZ60_07220	COG2199	diguanylate cyclase activity
FMZ60_07220	COG2200	EAL domain
FMZ60_07220	COG2202	Pas domain
FMZ60_07235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FMZ60_07245	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FMZ60_07255	COG4566	intracellular signal transduction
FMZ60_07260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FMZ60_07285	COG2217	Heavy metal translocating P-type atpase
FMZ60_07290	COG0789	Transcriptional regulator
FMZ60_07295	COG3180	Ammonia monooxygenase
FMZ60_07315	COG3541	Predicted nucleotidyltransferase
FMZ60_07325	COG0625	glutathione transferase activity
FMZ60_07340	COG1116	anion transmembrane transporter activity
FMZ60_07385	COG2233	PERMEase
FMZ60_07395	COG4598	ABC transporter
FMZ60_07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_07405	COG4215	(ABC) transporter
FMZ60_07420	COG0583	DNA-binding transcription factor activity
FMZ60_07425	COG1960	acyl-CoA dehydrogenase activity
FMZ60_07430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FMZ60_07435	COG0748	coenzyme F420 binding
FMZ60_07445	COG1960	acyl-CoA dehydrogenase activity
FMZ60_07450	COG2079	MmgE PrpD family protein
FMZ60_07455	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FMZ60_07465	COG2301	Belongs to the HpcH HpaI aldolase family
FMZ60_07540	COG2264	protein methyltransferase activity
FMZ60_07545	COG0583	DNA-binding transcription factor activity
FMZ60_07560	COG0765	amino acid transport
FMZ60_07570	COG0840	transmembrane signaling receptor activity
FMZ60_07595	COG0840	transmembrane signaling receptor activity
FMZ60_07600	COG1280	lysine exporter protein (LysE YggA)
FMZ60_07610	COG1280	lysine exporter protein (LysE YggA)
FMZ60_07615	COG0702	epimerase
FMZ60_07620	COG1733	regulation of RNA biosynthetic process
FMZ60_07630	COG1846	Transcriptional regulator
FMZ60_07645	COG0579	oxidoreductase
FMZ60_07670	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FMZ60_07725	COG0519	Catalyzes the synthesis of GMP from XMP
FMZ60_07725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FMZ60_07735	COG1320	monovalent cation:proton antiporter activity
FMZ60_07740	COG2212	antiporter activity
FMZ60_07745	COG1863	multisubunit Na H antiporter MnhE subunit
FMZ60_07750	COG0651	ATP synthesis coupled electron transport
FMZ60_07755	COG1006	Multisubunit Na H antiporter MnhC subunit
FMZ60_07760	COG2111	Na H antiporter
FMZ60_07760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FMZ60_07765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMZ60_07765	COG0047	phosphoribosylformylglycinamidine synthase activity
FMZ60_07795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FMZ60_07800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FMZ60_07825	COG4128	Pfam Zonular occludens toxin
FMZ60_07875	COG4974	Belongs to the 'phage' integrase family
FMZ60_07900	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FMZ60_07920	COG0613	PHP domain protein
FMZ60_07925	COG1027	Aspartate ammonia-lyase
FMZ60_07935	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FMZ60_07935	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FMZ60_07935	COG0506	proline dehydrogenase activity
FMZ60_07940	COG0542	response to heat
FMZ60_07945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FMZ60_07950	COG1278	Cold shock
FMZ60_07960	COG1570	exodeoxyribonuclease VII activity
FMZ60_07965	COG0811	peptide transport
FMZ60_07975	COG1663	tetraacyldisaccharide 4'-kinase activity
FMZ60_07980	COG2835	tetraacyldisaccharide 4'-kinase activity
FMZ60_07985	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FMZ60_07990	COG0563	adenylate kinase activity
FMZ60_08000	COG0728	peptidoglycan biosynthetic process
FMZ60_08005	COG0268	Binds directly to 16S ribosomal RNA
FMZ60_08010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMZ60_08020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FMZ60_08025	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FMZ60_08030	COG0137	argininosuccinate synthase activity
FMZ60_08045	COG0642	Histidine kinase
FMZ60_08050	COG0745	RESPONSE REGULATOR receiver
FMZ60_08090	COG0739	heme binding
FMZ60_08100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FMZ60_08105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FMZ60_08110	COG2356	endonuclease I
FMZ60_08125	COG0488	(ABC) transporter
FMZ60_08140	COG0254	rRNA binding
FMZ60_08150	COG0534	Mate efflux family protein
FMZ60_08155	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FMZ60_08165	COG1162	GTPase activity
FMZ60_08170	COG0494	nUDIX hydrolase
FMZ60_08175	COG0335	large ribosomal subunit rRNA binding
FMZ60_08185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FMZ60_08190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FMZ60_08200	COG2205	protein histidine kinase activity
FMZ60_08205	COG0745	RESPONSE REGULATOR receiver
FMZ60_08220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FMZ60_08225	COG4208	sulfate ABC transporter
FMZ60_08230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FMZ60_08235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FMZ60_08240	COG0450	alkyl hydroperoxide reductase
FMZ60_08245	COG1960	acyl-CoA dehydrogenase activity
FMZ60_08265	COG2951	lytic endotransglycosylase activity
FMZ60_08280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FMZ60_08285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FMZ60_08290	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FMZ60_08300	COG0776	regulation of translation
FMZ60_08330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FMZ60_08350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FMZ60_08360	COG2205	protein histidine kinase activity
FMZ60_08365	COG0745	RESPONSE REGULATOR receiver
FMZ60_08370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMZ60_08375	COG0577	efflux transmembrane transporter activity
FMZ60_08375	COG1136	(ABC) transporter
FMZ60_08380	COG1538	Outer membrane efflux protein
FMZ60_08400	COG0004	ammonium transporteR
FMZ60_08410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FMZ60_08415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FMZ60_08425	COG0189	ligase activity
FMZ60_08430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FMZ60_08435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FMZ60_08440	COG0628	permease
FMZ60_08450	COG0625	glutathione transferase activity
FMZ60_08455	COG0482	sulfurtransferase activity
FMZ60_08460	COG0277	FAD linked oxidase domain protein
FMZ60_08465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FMZ60_08470	COG2975	iron-sulfur cluster assembly
FMZ60_08475	COG0633	Ferredoxin
FMZ60_08480	COG0443	Heat shock 70 kDa protein
FMZ60_08485	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FMZ60_08490	COG0316	Belongs to the HesB IscA family
FMZ60_08495	COG0822	iron-sulfur transferase activity
FMZ60_08500	COG1104	cysteine desulfurase activity
FMZ60_08510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FMZ60_08515	COG0556	nucleotide-excision repair
FMZ60_08535	COG0756	dUTP diphosphatase activity
FMZ60_08540	COG0708	Exodeoxyribonuclease III
FMZ60_08735	COG4695	Portal protein
FMZ60_08745	COG1192	Involved in chromosome partitioning
FMZ60_08755	COG1610	YqeY-like protein
FMZ60_08760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FMZ60_08770	COG3585	molybdate ion transport
FMZ60_08775	COG1126	abc transporter atp-binding protein
FMZ60_08780	COG0765	amino acid transport
FMZ60_08795	COG3706	GGDEF domain
FMZ60_08825	COG3772	lysozyme
FMZ60_08850	COG3299	homolog of phage Mu protein gp47
FMZ60_08890	COG4386	tail sheath protein
FMZ60_08935	COG1802	Transcriptional regulator
FMZ60_08935	COG4626	Terminase
FMZ60_08985	COG0305	Participates in initiation and elongation during chromosome replication
FMZ60_09075	COG2974	May be involved in recombination
FMZ60_09135	COG0776	regulation of translation
FMZ60_09140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FMZ60_09140	COG0072	phenylalanine-tRNA ligase activity
FMZ60_09145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FMZ60_09150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FMZ60_09155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FMZ60_09165	COG1476	TRANSCRIPTIONal
FMZ60_09200	COG0671	phosphoesterase, PA-phosphatase related
FMZ60_09215	COG1618	nucleotide phosphatase activity, acting on free nucleotides
FMZ60_09215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FMZ60_09225	COG0217	transcriptional regulatory protein
FMZ60_09230	COG0151	Belongs to the GarS family
FMZ60_09235	COG0408	coproporphyrinogen oxidase activity
FMZ60_09240	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FMZ60_09245	COG0799	negative regulation of ribosome biogenesis
FMZ60_09250	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FMZ60_09255	COG0424	maF-like protein
FMZ60_09260	COG1530	ribonuclease E activity
FMZ60_09265	COG1132	(ABC) transporter
FMZ60_09280	COG3307	-O-antigen
FMZ60_09285	COG0726	polysaccharide deacetylase
FMZ60_09305	COG1643	Atp-dependent helicase
FMZ60_09320	COG0726	polysaccharide deacetylase
FMZ60_09330	COG0752	glycyl-tRNA synthetase alpha subunit
FMZ60_09335	COG0751	glycine-tRNA ligase activity
FMZ60_09340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FMZ60_09345	COG0204	Acyl-transferase
FMZ60_09360	COG0700	Nucleoside recognition
FMZ60_09365	COG1929	Belongs to the glycerate kinase type-1 family
FMZ60_09370	COG0006	proline dipeptidase activity
FMZ60_09375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FMZ60_09385	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FMZ60_09395	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FMZ60_09400	COG0632	four-way junction helicase activity
FMZ60_09405	COG1253	flavin adenine dinucleotide binding
FMZ60_09410	COG2833	Protein of unknown function (DUF455)
FMZ60_09420	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FMZ60_09425	COG0440	acetolactate synthase activity
FMZ60_09430	COG0028	Belongs to the TPP enzyme family
FMZ60_09435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FMZ60_09440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FMZ60_09440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FMZ60_09445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FMZ60_09450	COG0659	secondary active sulfate transmembrane transporter activity
FMZ60_09460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FMZ60_09475	COG1653	transport
FMZ60_09480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_09485	COG0543	2 iron, 2 sulfur cluster binding
FMZ60_09485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FMZ60_09490	COG5285	phytanoyl-CoA dioxygenase
FMZ60_09495	COG0662	Cupin 2, conserved barrel domain protein
FMZ60_09500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FMZ60_09505	COG0456	acetyltransferase
FMZ60_09510	COG1846	Transcriptional regulator
FMZ60_09530	COG3118	belongs to the thioredoxin family
FMZ60_09535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FMZ60_09565	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FMZ60_09570	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FMZ60_09580	COG2188	Transcriptional regulator
FMZ60_09585	COG2986	histidine ammonia-lyase
FMZ60_09600	COG0010	Belongs to the arginase family
FMZ60_09605	COG1228	amidohydrolase
FMZ60_09615	COG0084	hydrolase, TatD family'
FMZ60_09620	COG1136	(ABC) transporter
FMZ60_09635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FMZ60_09640	COG0501	Belongs to the peptidase M48B family
FMZ60_09660	COG4974	Belongs to the 'phage' integrase family
FMZ60_09670	COG0114	fumarate hydratase activity
FMZ60_09680	COG0860	N-Acetylmuramoyl-L-alanine amidase
FMZ60_09685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FMZ60_09690	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FMZ60_09705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FMZ60_09720	COG0617	tRNA 3'-terminal CCA addition
FMZ60_09745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FMZ60_09750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FMZ60_09755	COG0066	3-isopropylmalate dehydratase activity
FMZ60_09760	COG0473	3-isopropylmalate dehydrogenase activity
FMZ60_09765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FMZ60_09775	COG0101	tRNA pseudouridine synthase activity
FMZ60_09780	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FMZ60_09790	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FMZ60_09795	COG0135	phosphoribosylanthranilate isomerase activity
FMZ60_09800	COG4783	chaperone-mediated protein folding
FMZ60_09805	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FMZ60_09810	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FMZ60_09820	COG1295	ribonuclease BN
FMZ60_09830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FMZ60_09860	COG4964	Belongs to the GSP D family
FMZ60_09895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FMZ60_09915	COG0181	hydroxymethylbilane synthase activity
FMZ60_09920	COG0861	Integral membrane protein TerC family
FMZ60_09930	COG4977	sequence-specific DNA binding
FMZ60_09935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FMZ60_09940	COG0045	succinate-CoA ligase (ADP-forming) activity
FMZ60_09950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FMZ60_09955	COG0583	DNA-binding transcription factor activity
FMZ60_09960	COG2137	regulation of response to DNA damage stimulus
FMZ60_09965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FMZ60_09970	COG1283	sodium-dependent phosphate transmembrane transporter activity
FMZ60_09990	COG1007	ATP synthesis coupled electron transport
FMZ60_10005	COG0713	ATP synthesis coupled electron transport
FMZ60_10015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FMZ60_10020	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FMZ60_10025	COG1034	ATP synthesis coupled electron transport
FMZ60_10025	COG1034	ATP synthesis coupled electron transport
FMZ60_10035	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FMZ60_10040	COG0649	NAD binding
FMZ60_10045	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FMZ60_10050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FMZ60_10055	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FMZ60_10060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FMZ60_10065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FMZ60_10070	COG1160	GTP binding
FMZ60_10075	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FMZ60_10085	COG0124	histidyl-tRNA synthetase
FMZ60_10090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FMZ60_10100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FMZ60_10105	COG0105	UTP biosynthetic process
FMZ60_10115	COG0525	valine-tRNA ligase activity
FMZ60_10120	COG0745	RESPONSE REGULATOR receiver
FMZ60_10130	COG0336	Belongs to the RNA methyltransferase TrmD family
FMZ60_10135	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FMZ60_10140	COG0228	four-way junction DNA binding
FMZ60_10150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FMZ60_10155	COG0148	phosphopyruvate hydratase activity
FMZ60_10165	COG0504	CTP synthase activity
FMZ60_10175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FMZ60_10185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FMZ60_10190	COG0509	glycine decarboxylation via glycine cleavage system
FMZ60_10200	COG2081	HI0933 family
FMZ60_10205	COG1982	Orn Lys Arg decarboxylase major
FMZ60_10215	COG0717	Belongs to the dCTP deaminase family
FMZ60_10230	COG0489	protein tyrosine kinase activity
FMZ60_10270	COG1289	transmembrane transporter activity
FMZ60_10285	COG0133	tryptophan synthase activity
FMZ60_10305	COG1120	ATPase activity
FMZ60_10310	COG4139	cobalamin transport
FMZ60_10320	COG2814	Major facilitator Superfamily
FMZ60_10330	COG3712	iron ion homeostasis
FMZ60_10335	COG1595	DNA-templated transcription, initiation
FMZ60_10340	COG2205	protein histidine kinase activity
FMZ60_10385	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FMZ60_10395	COG0861	Integral membrane protein TerC family
FMZ60_10400	COG2199	diguanylate cyclase activity
FMZ60_10400	COG2200	EAL domain
FMZ60_10400	COG2202	Pas domain
FMZ60_10410	COG0288	reversible hydration of carbon dioxide
FMZ60_10445	COG0318	PFAM AMP-dependent synthetase and ligase
FMZ60_10455	COG0183	Belongs to the thiolase family
FMZ60_10460	COG1250	3-hydroxyacyl-CoA dehydrogenase
FMZ60_10460	COG1024	Enoyl-CoA hydratase
FMZ60_10465	COG2067	long-chain fatty acid transport protein
FMZ60_10470	COG1024	Enoyl-CoA hydratase
FMZ60_10470	COG1250	3-hydroxyacyl-CoA dehydrogenase
FMZ60_10485	COG0589	response to stress
FMZ60_10490	COG2814	Major facilitator Superfamily
FMZ60_10500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FMZ60_10520	COG1902	pentaerythritol trinitrate reductase activity
FMZ60_10525	COG4535	Mg2 and Co2 transporter CorC
FMZ60_10530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FMZ60_10535	COG1045	serine acetyltransferase
FMZ60_10540	COG1381	Involved in DNA repair and RecF pathway recombination
FMZ60_10545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FMZ60_10550	COG0571	ribonuclease III activity
FMZ60_10555	COG0681	Belongs to the peptidase S26 family
FMZ60_10560	COG0481	GTPase activity
FMZ60_10565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FMZ60_10590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FMZ60_10595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FMZ60_10605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FMZ60_10610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FMZ60_10615	COG0416	fatty acid biosynthetic process
FMZ60_10620	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FMZ60_10625	COG1399	metal-binding, possibly nucleic acid-binding protein
FMZ60_10630	COG3706	GGDEF domain
FMZ60_10630	COG0745	RESPONSE REGULATOR receiver
FMZ60_10635	COG0542	response to heat
FMZ60_10640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FMZ60_10645	COG0679	Auxin Efflux Carrier
FMZ60_10650	COG2140	Oxalate decarboxylase
FMZ60_10660	COG2010	Cytochrome c
FMZ60_10675	COG3278	Belongs to the heme-copper respiratory oxidase family
FMZ60_10685	COG2217	Heavy metal translocating P-type atpase
FMZ60_10690	COG2224	Isocitrate lyase
FMZ60_10700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMZ60_10705	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMZ60_10710	COG0633	Ferredoxin
FMZ60_10720	COG3228	Belongs to the MtfA family
FMZ60_10725	COG2814	Major facilitator Superfamily
FMZ60_10730	COG2910	NAD(P)H-binding
FMZ60_10735	COG1733	regulation of RNA biosynthetic process
FMZ60_10740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FMZ60_10745	COG2850	peptidyl-arginine hydroxylation
FMZ60_10760	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FMZ60_10765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FMZ60_10770	COG1994	Peptidase M50
FMZ60_10775	COG0009	L-threonylcarbamoyladenylate synthase
FMZ60_10795	COG3012	SEC-C Motif Domain Protein
FMZ60_10795	COG3318	Belongs to the UPF0149 family
FMZ60_10805	COG0583	DNA-binding transcription factor activity
FMZ60_10820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FMZ60_10870	COG4964	Belongs to the GSP D family
FMZ60_10905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FMZ60_10925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FMZ60_10930	COG0248	Ppx GppA phosphatase
FMZ60_10940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FMZ60_10950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FMZ60_10955	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FMZ60_10960	COG1534	Rna-binding protein
FMZ60_10970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FMZ60_10980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FMZ60_10985	COG0505	Belongs to the CarA family
FMZ60_10990	COG3706	GGDEF domain
FMZ60_10995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FMZ60_11000	COG2814	Major facilitator Superfamily
FMZ60_11010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FMZ60_11030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FMZ60_11040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FMZ60_11055	COG0840	transmembrane signaling receptor activity
FMZ60_11085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FMZ60_11090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FMZ60_11095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMZ60_11100	COG0328	RNA-DNA hybrid ribonuclease activity
FMZ60_11105	COG2226	methyltransferase
FMZ60_11110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FMZ60_11115	COG1388	LysM domain
FMZ60_11115	COG0741	lytic transglycosylase activity
FMZ60_11130	COG2832	Protein of unknown function (DUF454)
FMZ60_11135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FMZ60_11140	COG0459	protein refolding
FMZ60_11145	COG4771	TonB-dependent receptor
FMZ60_11155	COG1595	DNA-templated transcription, initiation
FMZ60_11170	COG0284	orotidine-5'-phosphate decarboxylase activity
FMZ60_11175	COG1546	Belongs to the CinA family
FMZ60_11175	COG1058	Belongs to the CinA family
FMZ60_11180	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FMZ60_11190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FMZ60_11195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FMZ60_11220	COG0742	ribosomal rna small subunit methyltransferase
FMZ60_11225	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FMZ60_11230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FMZ60_11250	COG1309	transcriptional regulator
FMZ60_11280	COG1309	transcriptional regulator
FMZ60_11295	COG0484	heat shock protein binding
FMZ60_11300	COG0443	Heat shock 70 kDa protein
FMZ60_11305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FMZ60_11310	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FMZ60_11315	COG1420	regulation of RNA biosynthetic process
FMZ60_11320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FMZ60_11325	COG0497	DNA recombination
FMZ60_11330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FMZ60_11335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FMZ60_11340	COG0668	transmembrane transport
FMZ60_11345	COG0519	Catalyzes the synthesis of GMP from XMP
FMZ60_11345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FMZ60_11350	COG0521	Mo-molybdopterin cofactor biosynthetic process
FMZ60_11355	COG0679	Auxin Efflux Carrier
FMZ60_11360	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FMZ60_11375	COG2223	nitrite transmembrane transporter activity
FMZ60_11385	COG0583	DNA-binding transcription factor activity
FMZ60_11435	COG1595	DNA-templated transcription, initiation
FMZ60_11440	COG3712	iron ion homeostasis
FMZ60_11460	COG0326	Molecular chaperone. Has ATPase activity
FMZ60_11480	COG4585	Histidine kinase
FMZ60_11485	COG0583	DNA-binding transcription factor activity
FMZ60_11490	COG0747	negative chemotaxis
FMZ60_11495	COG0601	transmembrane transport
FMZ60_11500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMZ60_11510	COG4608	Belongs to the ABC transporter superfamily
FMZ60_11515	COG1473	amidohydrolase
FMZ60_11520	COG0625	glutathione transferase activity
FMZ60_11530	COG0477	Major facilitator Superfamily
FMZ60_11535	COG1473	amidohydrolase
FMZ60_11540	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FMZ60_11550	COG1252	NADH dehydrogenase
FMZ60_11565	COG1272	protein, Hemolysin III
FMZ60_11570	COG1321	iron dependent repressor
FMZ60_11575	COG0803	Belongs to the bacterial solute-binding protein 9 family
FMZ60_11580	COG1121	(ABC) transporter
FMZ60_11585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FMZ60_11590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FMZ60_11595	COG3781	membrane
FMZ60_11605	COG0142	geranyltranstransferase activity
FMZ60_11635	COG1760	l-serine dehydratase
FMZ60_11640	COG1473	amidohydrolase
FMZ60_11645	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_11650	COG2084	Dehydrogenase
FMZ60_11660	COG0583	DNA-binding transcription factor activity
FMZ60_11670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FMZ60_11675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FMZ60_11680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FMZ60_11685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FMZ60_11700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FMZ60_11715	COG0745	RESPONSE REGULATOR receiver
FMZ60_11725	COG2198	Histidine kinase
FMZ60_11725	COG0643	Histidine kinase
FMZ60_11730	COG0840	transmembrane signaling receptor activity
FMZ60_11735	COG0835	chemotaxis
FMZ60_11740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FMZ60_11745	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FMZ60_11750	COG2201	protein-glutamate methylesterase activity
FMZ60_11775	COG4953	penicillin-binding protein 1C
FMZ60_11780	COG2373	Large extracellular alpha-helical protein
FMZ60_11785	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_11810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_11830	COG2022	thiamine diphosphate biosynthetic process
FMZ60_11835	COG0351	phosphomethylpyrimidine kinase
FMZ60_11840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FMZ60_11850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FMZ60_11860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FMZ60_11870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FMZ60_11875	COG1678	Uncharacterized ACR, COG1678
FMZ60_11895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FMZ60_11910	COG0471	metal ion transport
FMZ60_11915	COG0039	L-malate dehydrogenase activity
FMZ60_11940	COG0583	DNA-binding transcription factor activity
FMZ60_11945	COG1380	Effector of murein hydrolase LrgA
FMZ60_11950	COG1346	cytolysis
FMZ60_11960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FMZ60_11965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FMZ60_11970	COG4771	TonB-dependent receptor
FMZ60_11975	COG0745	RESPONSE REGULATOR receiver
FMZ60_11980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FMZ60_11995	COG2226	methyltransferase
FMZ60_12000	COG0745	RESPONSE REGULATOR receiver
FMZ60_12020	COG1238	metal cluster binding
FMZ60_12035	COG0601	transmembrane transport
FMZ60_12040	COG0747	negative chemotaxis
FMZ60_12045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FMZ60_12050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FMZ60_12055	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FMZ60_12065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FMZ60_12075	COG0210	DNA helicase
FMZ60_12080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FMZ60_12085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FMZ60_12100	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FMZ60_12105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FMZ60_12110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FMZ60_12115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FMZ60_12120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FMZ60_12125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FMZ60_12130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FMZ60_12140	COG0356	it plays a direct role in the translocation of protons across the membrane
FMZ60_12150	COG0758	DNA mediated transformation
FMZ60_12160	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FMZ60_12175	COG3433	isochorismatase activity
FMZ60_12175	COG1535	isochorismatase
FMZ60_12180	COG1021	2,3-dihydroxybenzoate-AMP ligase
FMZ60_12185	COG0410	ABC transporter
FMZ60_12190	COG0411	ABC transporter
FMZ60_12205	COG0683	leucine binding
FMZ60_12210	COG2819	hydrolase of the alpha beta superfamily
FMZ60_12225	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FMZ60_12240	COG1137	ATPase activity
FMZ60_12245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FMZ60_12255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FMZ60_12275	COG0792	nuclease activity
FMZ60_12280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FMZ60_12280	COG2010	Cytochrome c
FMZ60_12305	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FMZ60_12310	COG2823	Periplasmic or secreted lipoprotein
FMZ60_12325	COG2011	ABC-type metal ion transport system permease component
FMZ60_12330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMZ60_12335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FMZ60_12345	COG0471	metal ion transport
FMZ60_12350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FMZ60_12355	COG0793	Belongs to the peptidase S41A family
FMZ60_12360	COG4942	peptidase
FMZ60_12365	COG0588	phosphoglycerate mutase activity
FMZ60_12380	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FMZ60_12385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FMZ60_12395	COG1040	competence protein
FMZ60_12400	COG2226	methyltransferase
FMZ60_12405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FMZ60_12410	COG0569	domain protein
FMZ60_12415	COG2204	response regulator
FMZ60_12420	COG5000	phosphorelay sensor kinase activity
FMZ60_12430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FMZ60_12440	COG0668	transmembrane transport
FMZ60_12445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FMZ60_12450	COG0242	peptide deformylase activity
FMZ60_12460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FMZ60_12475	COG1176	ABC-type spermidine putrescine transport system, permease component I
FMZ60_12490	COG4771	TonB-dependent receptor
FMZ60_12515	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FMZ60_12520	COG1024	Enoyl-CoA hydratase
FMZ60_12540	COG1113	amino acid transport
FMZ60_12545	COG2423	ornithine cyclodeaminase activity
FMZ60_12555	COG0463	Glycosyl transferase, family 2
FMZ60_12560	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FMZ60_12570	COG5002	protein histidine kinase activity
FMZ60_12575	COG1368	sulfuric ester hydrolase activity
FMZ60_12615	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_12625	COG0037	tRNA processing
FMZ60_12640	COG2900	Belongs to the SlyX family
FMZ60_12660	COG0513	Belongs to the DEAD box helicase family
FMZ60_12665	COG1280	lysine exporter protein (LysE YggA)
FMZ60_12675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FMZ60_12680	COG1741	Belongs to the pirin family
FMZ60_12685	COG0583	DNA-binding transcription factor activity
FMZ60_12690	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FMZ60_12710	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FMZ60_12715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FMZ60_12725	COG0697	spore germination
FMZ60_12730	COG1846	Transcriptional regulator
FMZ60_12735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FMZ60_12740	COG1780	Probably involved in ribonucleotide reductase function
FMZ60_12750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMZ60_12760	COG1595	DNA-templated transcription, initiation
FMZ60_12785	COG2326	polyphosphate kinase activity
FMZ60_12790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FMZ60_12810	COG0251	oxidation-reduction process
FMZ60_12815	COG1028	Short-chain dehydrogenase reductase Sdr
FMZ60_12820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FMZ60_12835	COG0745	RESPONSE REGULATOR receiver
FMZ60_12840	COG2205	protein histidine kinase activity
FMZ60_12845	COG1595	DNA-templated transcription, initiation
FMZ60_12870	COG5265	(ABC) transporter
FMZ60_12890	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FMZ60_12895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FMZ60_12900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FMZ60_12920	COG0095	Lipoate-protein ligase
FMZ60_12930	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FMZ60_12935	COG0237	dephospho-CoA kinase activity
FMZ60_12940	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FMZ60_12950	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FMZ60_12975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FMZ60_12985	COG1126	abc transporter atp-binding protein
FMZ60_12990	COG0765	amino acid transport
FMZ60_12995	COG4597	amino acid ABC transporter
FMZ60_13000	COG5001	Diguanylate cyclase
FMZ60_13005	COG2884	Cell division ATP-binding protein ftsE
FMZ60_13010	COG2177	Part of the ABC transporter FtsEX involved in
FMZ60_13015	COG1194	a g-specific adenine glycosylase
FMZ60_13020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FMZ60_13045	COG0772	Belongs to the SEDS family
FMZ60_13050	COG0768	penicillin binding
FMZ60_13060	COG1792	Involved in formation and maintenance of cell shape
FMZ60_13065	COG1077	Cell shape determining protein MreB Mrl
FMZ60_13070	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FMZ60_13075	COG0154	amidase activity
FMZ60_13080	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FMZ60_13090	COG2345	Transcriptional regulator
FMZ60_13105	COG0840	transmembrane signaling receptor activity
FMZ60_13110	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FMZ60_13120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FMZ60_13135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FMZ60_13140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FMZ60_13145	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FMZ60_13150	COG2967	ApaG domain
FMZ60_13160	COG0546	phosphoglycolate phosphatase activity
FMZ60_13165	COG0617	tRNA 3'-terminal CCA addition
FMZ60_13170	COG0741	lytic transglycosylase activity
FMZ60_13175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FMZ60_13180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FMZ60_13180	COG0646	methionine synthase
FMZ60_13185	COG0747	negative chemotaxis
FMZ60_13190	COG0601	transmembrane transport
FMZ60_13195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FMZ60_13200	COG4172	Belongs to the ABC transporter superfamily
FMZ60_13205	COG1309	transcriptional regulator
FMZ60_13210	COG0840	transmembrane signaling receptor activity
FMZ60_13215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FMZ60_13220	COG1950	PFAM Membrane protein of
FMZ60_13225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FMZ60_13230	COG0583	DNA-binding transcription factor activity
FMZ60_13235	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_13240	COG1454	alcohol dehydrogenase
FMZ60_13245	COG3038	cytochrome b561
FMZ60_13250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FMZ60_13255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FMZ60_13260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FMZ60_13270	COG0277	FAD linked oxidase domain protein
FMZ60_13275	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_13280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMZ60_13285	COG2011	ABC-type metal ion transport system permease component
FMZ60_13310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FMZ60_13330	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_13335	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_13340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMZ60_13345	COG2011	ABC-type metal ion transport system permease component
FMZ60_13360	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_13370	COG1464	Belongs to the NlpA lipoprotein family
FMZ60_13375	COG0431	NADPH-dependent FMN reductase
FMZ60_13385	COG3829	transcription factor binding
FMZ60_13390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FMZ60_13400	COG0579	oxidoreductase
FMZ60_13410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FMZ60_13420	COG1560	Kdo2-lipid A biosynthetic process
FMZ60_13425	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FMZ60_13440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FMZ60_13495	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FMZ60_13505	COG0803	Belongs to the bacterial solute-binding protein 9 family
FMZ60_13510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FMZ60_13515	COG1121	(ABC) transporter
FMZ60_13525	COG0735	belongs to the Fur family
FMZ60_13530	COG0523	cobalamin synthesis protein
FMZ60_13535	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FMZ60_13540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FMZ60_13545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FMZ60_13565	COG1126	abc transporter atp-binding protein
FMZ60_13570	COG0765	amino acid transport
FMZ60_13575	COG4597	amino acid ABC transporter
FMZ60_13580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_13585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FMZ60_13590	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FMZ60_13595	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FMZ60_13605	COG3721	Heme iron utilization protein
FMZ60_13615	COG2146	nitrite reductase [NAD(P)H] activity
FMZ60_13615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FMZ60_13620	COG2146	nitrite reductase [NAD(P)H] activity
FMZ60_13620	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FMZ60_13625	COG1116	anion transmembrane transporter activity
FMZ60_13625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FMZ60_13635	COG1116	anion transmembrane transporter activity
FMZ60_13640	COG0243	molybdopterin cofactor binding
FMZ60_13650	COG3707	response regulator
FMZ60_13655	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FMZ60_13660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FMZ60_13675	COG4215	(ABC) transporter
FMZ60_13680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_13730	COG1301	dicarboxylic acid transport
FMZ60_13735	COG4191	Histidine kinase
FMZ60_13740	COG2204	response regulator
FMZ60_13745	COG2188	Transcriptional regulator
FMZ60_13765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FMZ60_13780	COG1686	Belongs to the peptidase S11 family
FMZ60_13785	COG2945	thiolester hydrolase activity
FMZ60_13800	COG1127	ABC transporter
FMZ60_13805	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FMZ60_13815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FMZ60_13835	COG0859	PFAM glycosyl transferase family 9
FMZ60_13840	COG0477	Major facilitator Superfamily
FMZ60_13855	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FMZ60_13885	COG0436	Aminotransferase
FMZ60_13900	COG1126	abc transporter atp-binding protein
FMZ60_13905	COG0765	amino acid transport
FMZ60_13910	COG0765	amino acid transport
FMZ60_13915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_13925	COG2814	Major facilitator Superfamily
FMZ60_13930	COG1566	PFAM secretion protein HlyD family protein
FMZ60_13935	COG1538	Outer membrane efflux protein
FMZ60_13940	COG1846	Transcriptional regulator
FMZ60_13945	COG1063	alcohol dehydrogenase
FMZ60_13975	COG2807	transmembrane transport
FMZ60_13980	COG0590	tRNA wobble adenosine to inosine editing
FMZ60_14000	COG4191	Histidine kinase
FMZ60_14005	COG0629	single-stranded DNA binding
FMZ60_14010	COG2814	Major facilitator Superfamily
FMZ60_14035	COG0500	methyltransferase
FMZ60_14045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMZ60_14050	COG1120	ATPase activity
FMZ60_14070	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FMZ60_14075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FMZ60_14090	COG1965	Belongs to the frataxin family
FMZ60_14095	COG0019	diaminopimelate decarboxylase activity
FMZ60_14100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FMZ60_14105	COG1333	cytochrome c biogenesis protein
FMZ60_14115	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FMZ60_14125	COG4232	protein-disulfide reductase activity
FMZ60_14130	COG1324	tolerance protein
FMZ60_14135	COG0583	DNA-binding transcription factor activity
FMZ60_14150	COG0765	amino acid transport
FMZ60_14155	COG0765	amino acid transport
FMZ60_14175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FMZ60_14180	COG0203	ribosomal protein L17
FMZ60_14185	COG0202	RNA polymerase activity
FMZ60_14190	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FMZ60_14195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FMZ60_14200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FMZ60_14205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FMZ60_14210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FMZ60_14215	COG0201	protein transport
FMZ60_14220	COG0200	Binds to the 23S rRNA
FMZ60_14225	COG1841	ribosomal large subunit assembly
FMZ60_14230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FMZ60_14235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FMZ60_14240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FMZ60_14245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FMZ60_14250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FMZ60_14255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FMZ60_14260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FMZ60_14265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FMZ60_14280	COG1595	DNA-templated transcription, initiation
FMZ60_14295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FMZ60_14305	COG0477	Major facilitator Superfamily
FMZ60_14315	COG1984	allophanate hydrolase subunit 2
FMZ60_14320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FMZ60_14330	COG0439	Biotin carboxylase
FMZ60_14340	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FMZ60_14345	COG0255	Belongs to the universal ribosomal protein uL29 family
FMZ60_14350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FMZ60_14355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FMZ60_14360	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FMZ60_14365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FMZ60_14370	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FMZ60_14375	COG0089	rRNA binding
FMZ60_14380	COG0088	Forms part of the polypeptide exit tunnel
FMZ60_14385	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FMZ60_14405	COG2197	response regulator
FMZ60_14415	COG1966	Carbon starvation protein
FMZ60_14420	COG2879	small protein
FMZ60_14445	COG2197	response regulator
FMZ60_14450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FMZ60_14465	COG1538	Outer membrane efflux protein
FMZ60_14475	COG0051	transcription antitermination factor activity, RNA binding
FMZ60_14480	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FMZ60_14485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FMZ60_14490	COG0049	tRNA binding
FMZ60_14495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FMZ60_14500	COG1677	Flagellar hook-basal body complex protein FliE
FMZ60_14505	COG1766	The M ring may be actively involved in energy transduction
FMZ60_14510	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FMZ60_14520	COG1157	protein secretion by the type III secretion system
FMZ60_14545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FMZ60_14550	COG3190	flagellar
FMZ60_14560	COG1987	bacterial-type flagellum assembly
FMZ60_14570	COG0840	transmembrane signaling receptor activity
FMZ60_14580	COG0840	transmembrane signaling receptor activity
FMZ60_14600	COG1256	bacterial-type flagellum assembly
FMZ60_14610	COG1706	bacterial-type flagellum-dependent cell motility
FMZ60_14620	COG4786	Flagellar basal body rod
FMZ60_14625	COG4787	bacterial-type flagellum-dependent cell motility
FMZ60_14630	COG1749	Flagellar hook protein flgE
FMZ60_14635	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FMZ60_14640	COG1558	bacterial-type flagellum-dependent cell motility
FMZ60_14670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FMZ60_14680	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FMZ60_14685	COG0745	RESPONSE REGULATOR receiver
FMZ60_14690	COG2201	protein-glutamate methylesterase activity
FMZ60_14695	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FMZ60_14700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FMZ60_14715	COG0643	Histidine kinase
FMZ60_14715	COG2198	Histidine kinase
FMZ60_14770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FMZ60_14775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FMZ60_14810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FMZ60_14815	COG1215	transferase activity, transferring glycosyl groups
FMZ60_14820	COG0438	transferase activity, transferring glycosyl groups
FMZ60_14820	COG1216	Glycosyl transferase, family 2
FMZ60_14830	COG0582	viral genome integration into host DNA
FMZ60_14840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FMZ60_14840	COG4797	methyltransferase
FMZ60_14870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMZ60_14900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FMZ60_14905	COG1138	Cytochrome C-type biogenesis protein
FMZ60_14910	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FMZ60_14930	COG4133	protoheme IX ABC transporter activity
FMZ60_14935	COG3005	denitrification pathway
FMZ60_14940	COG3043	anaerobic respiration
FMZ60_14945	COG0348	domain, Protein
FMZ60_14955	COG0243	molybdopterin cofactor binding
FMZ60_14980	COG3550	peptidyl-serine autophosphorylation
FMZ60_14985	COG1522	sequence-specific DNA binding
FMZ60_14990	COG0583	DNA-binding transcription factor activity
FMZ60_14995	COG0473	3-isopropylmalate dehydrogenase activity
FMZ60_15000	COG1396	sequence-specific DNA binding
FMZ60_15015	COG3012	SEC-C Motif Domain Protein
FMZ60_15035	COG4172	Belongs to the ABC transporter superfamily
FMZ60_15045	COG0601	transmembrane transport
FMZ60_15055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_15065	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_15100	COG0840	transmembrane signaling receptor activity
FMZ60_15145	COG3300	MHYT domain
FMZ60_15145	COG5001	Diguanylate cyclase
FMZ60_15150	COG1191	sigma factor activity
FMZ60_15155	COG0436	Aminotransferase
FMZ60_15160	COG4574	serine-type endopeptidase inhibitor activity
FMZ60_15165	COG0445	tRNA wobble uridine modification
FMZ60_15170	COG0357	Ribosomal RNA small subunit methyltransferase G
FMZ60_15175	COG1192	Involved in chromosome partitioning
FMZ60_15180	COG1475	DNA binding
FMZ60_15200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FMZ60_15210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FMZ60_15220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FMZ60_15225	COG0081	regulation of translation
FMZ60_15230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FMZ60_15235	COG0222	ribosome binding
FMZ60_15240	COG0085	RNA polymerase activity
FMZ60_15245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMZ60_15255	COG5002	protein histidine kinase activity
FMZ60_15270	COG0745	RESPONSE REGULATOR receiver
FMZ60_15280	COG1047	Peptidyl-prolyl cis-trans
FMZ60_15295	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FMZ60_15305	COG3712	iron ion homeostasis
FMZ60_15315	COG3284	Transcriptional regulator
FMZ60_15320	COG1012	belongs to the aldehyde dehydrogenase family
FMZ60_15330	COG3706	GGDEF domain
FMZ60_15375	COG0840	transmembrane signaling receptor activity
FMZ60_15385	COG0067	glutamate synthase
FMZ60_15385	COG0069	glutamate synthase activity
FMZ60_15385	COG0070	glutamate synthase
FMZ60_15395	COG0457	Tetratricopeptide repeat
FMZ60_15400	COG0438	transferase activity, transferring glycosyl groups
FMZ60_15425	COG4783	chaperone-mediated protein folding
FMZ60_15425	COG1560	Kdo2-lipid A biosynthetic process
FMZ60_15430	COG3866	Pectate lyase
FMZ60_15440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FMZ60_15445	COG3204	pilus organization
FMZ60_15480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FMZ60_15485	COG2814	Major facilitator Superfamily
FMZ60_15495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FMZ60_15515	COG1045	serine acetyltransferase
FMZ60_15525	COG0583	DNA-binding transcription factor activity
FMZ60_15555	COG4608	Belongs to the ABC transporter superfamily
FMZ60_15560	COG1024	Enoyl-CoA hydratase
FMZ60_15565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FMZ60_15580	COG2011	ABC-type metal ion transport system permease component
FMZ60_15585	COG0583	DNA-binding transcription factor activity
FMZ60_15595	COG3842	ATPase activity
FMZ60_15600	COG1176	ABC-type spermidine putrescine transport system, permease component I
FMZ60_15605	COG1177	transmembrane transport
FMZ60_15625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FMZ60_15630	COG0251	oxidation-reduction process
FMZ60_15640	COG0134	indole-3-glycerol-phosphate synthase activity
FMZ60_15645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FMZ60_15650	COG0512	Glutamine amidotransferase of anthranilate synthase
FMZ60_15660	COG0277	FAD linked oxidase domain protein
FMZ60_15665	COG1304	FMN binding
FMZ60_15670	COG2186	Transcriptional regulator
FMZ60_15675	COG1620	l-lactate permease
FMZ60_15680	COG1490	D-aminoacyl-tRNA deacylase activity
FMZ60_15695	COG4263	nitrous-oxide reductase activity
FMZ60_15710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FMZ60_15730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FMZ60_15740	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FMZ60_15745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FMZ60_15750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FMZ60_15760	COG0842	Transport permease protein
FMZ60_15765	COG1131	(ABC) transporter
FMZ60_15790	COG3639	organic phosphonate transmembrane transporter activity
FMZ60_15820	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FMZ60_15830	COG3284	Transcriptional regulator
FMZ60_15860	COG0405	Gamma-glutamyltransferase
FMZ60_15865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FMZ60_15875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FMZ60_15880	COG0765	amino acid transport
FMZ60_15885	COG0765	amino acid transport
FMZ60_15900	COG0688	phosphatidylethanolamine metabolic process
FMZ60_15930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FMZ60_15940	COG4149	molybdate abc transporter
FMZ60_15945	COG0157	Belongs to the NadC ModD family
FMZ60_15960	COG3391	amine dehydrogenase activity
FMZ60_15965	COG4774	siderophore transport
FMZ60_15965	COG1629	transport
FMZ60_15975	COG1595	DNA-templated transcription, initiation
FMZ60_15980	COG4558	Periplasmic binding protein
FMZ60_15985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMZ60_15990	COG1120	ATPase activity
FMZ60_15995	COG0745	RESPONSE REGULATOR receiver
FMZ60_16000	COG2205	protein histidine kinase activity
FMZ60_16020	COG4964	Belongs to the GSP D family
FMZ60_16105	COG0583	DNA-binding transcription factor activity
FMZ60_16120	COG0583	DNA-binding transcription factor activity
FMZ60_16125	COG1247	-acetyltransferase
FMZ60_16135	COG2186	Transcriptional regulator
FMZ60_16140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FMZ60_16145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FMZ60_16150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FMZ60_16155	COG4948	Mandelate Racemase Muconate Lactonizing
FMZ60_16160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FMZ60_16175	COG1764	response to oxidative stress
FMZ60_16180	COG1846	Transcriptional regulator
FMZ60_16185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FMZ60_16195	COG4521	taurine ABC transporter
FMZ60_16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FMZ60_16205	COG1116	anion transmembrane transporter activity
FMZ60_16210	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FMZ60_16230	COG1196	nuclear chromosome segregation
FMZ60_16245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FMZ60_16260	COG4336	lyase activity
FMZ60_16265	COG0583	DNA-binding transcription factor activity
FMZ60_16275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FMZ60_16285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FMZ60_16295	COG0732	type I restriction modification DNA specificity domain
FMZ60_16300	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FMZ60_16320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FMZ60_16330	COG0706	membrane insertase activity
FMZ60_16335	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FMZ60_16340	COG0594	ribonuclease P activity
FMZ60_16345	COG0230	Belongs to the bacterial ribosomal protein bL34 family