locus-tag	class	description
FE795_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE795_00020	COG1187	pseudouridine synthase activity
FE795_00025	COG1802	Transcriptional regulator
FE795_00030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_00050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FE795_00055	COG0583	DNA-binding transcription factor activity
FE795_00065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FE795_00075	COG0559	Belongs to the binding-protein-dependent transport system permease family
FE795_00090	COG0318	PFAM AMP-dependent synthetase and ligase
FE795_00100	COG0596	Alpha beta hydrolase
FE795_00100	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE795_00105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE795_00120	COG3181	Tripartite tricarboxylate transporter family receptor
FE795_00130	COG0697	spore germination
FE795_00135	COG0583	DNA-binding transcription factor activity
FE795_00145	COG3842	ATPase activity
FE795_00155	COG0436	Aminotransferase
FE795_00165	COG0523	cobalamin synthesis protein
FE795_00180	COG0625	glutathione transferase activity
FE795_00220	COG1846	Transcriptional regulator
FE795_00240	COG0179	Fumarylacetoacetate (FAA) hydrolase
FE795_00245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE795_00250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FE795_00315	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_00325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE795_00340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE795_00355	COG4608	Belongs to the ABC transporter superfamily
FE795_00360	COG0444	Belongs to the ABC transporter superfamily
FE795_00365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE795_00370	COG0601	transmembrane transport
FE795_00375	COG4166	transmembrane transport
FE795_00380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE795_00385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE795_00400	COG1464	Belongs to the NlpA lipoprotein family
FE795_00405	COG1464	Belongs to the NlpA lipoprotein family
FE795_00410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE795_00415	COG2011	ABC-type metal ion transport system permease component
FE795_00440	COG1464	Belongs to the NlpA lipoprotein family
FE795_00450	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FE795_00470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE795_00475	COG0431	NADPH-dependent FMN reductase
FE795_00495	COG4149	molybdate abc transporter
FE795_00505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FE795_00510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE795_00515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FE795_00535	COG0028	Belongs to the TPP enzyme family
FE795_00540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FE795_00590	COG2922	Belongs to the Smg family
FE795_00595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE795_00605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE795_00610	COG0183	Belongs to the thiolase family
FE795_00615	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FE795_00620	COG1960	acyl-CoA dehydrogenase activity
FE795_00640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE795_00650	COG0018	arginyl-trna synthetase
FE795_00680	COG1982	Orn Lys Arg decarboxylase major
FE795_00685	COG0531	amino acid
FE795_00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE795_00700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FE795_00705	COG0066	3-isopropylmalate dehydratase activity
FE795_00710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FE795_00715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE795_00720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE795_00725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FE795_00725	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_00735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FE795_00740	COG1335	isochorismatase
FE795_00745	COG0583	DNA-binding transcription factor activity
FE795_00765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FE795_00770	COG1280	lysine exporter protein (LysE YggA)
FE795_00775	COG0513	Belongs to the DEAD box helicase family
FE795_00785	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FE795_00800	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE795_00850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE795_00855	COG1127	ABC transporter
FE795_00875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE795_00880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FE795_00890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_00920	COG0583	DNA-binding transcription factor activity
FE795_00955	COG2358	TRAP transporter, solute receptor (TAXI family
FE795_00970	COG0252	asparaginase activity
FE795_00995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FE795_01000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE795_01005	COG3181	Tripartite tricarboxylate transporter family receptor
FE795_01050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_01065	COG0758	DNA mediated transformation
FE795_01070	COG0242	peptide deformylase activity
FE795_01075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FE795_01080	COG0697	spore germination
FE795_01095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_01110	COG4336	lyase activity
FE795_01115	COG0583	DNA-binding transcription factor activity
FE795_01120	COG0859	PFAM glycosyl transferase family 9
FE795_01130	COG1278	Cold shock
FE795_01135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE795_01145	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FE795_01150	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FE795_01150	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FE795_01160	COG1686	Belongs to the peptidase S11 family
FE795_01170	COG2921	Belongs to the UPF0250 family
FE795_01175	COG0321	lipoyl(octanoyl) transferase activity
FE795_01180	COG1024	Enoyl-CoA hydratase
FE795_01185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE795_01195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE795_01240	COG0826	peptidase U32
FE795_01250	COG3154	lipid carrier protein
FE795_01275	COG0134	indole-3-glycerol-phosphate synthase activity
FE795_01280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE795_01285	COG0512	Glutamine amidotransferase of anthranilate synthase
FE795_01295	COG0546	phosphoglycolate phosphatase activity
FE795_01305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FE795_01310	COG2967	ApaG domain
FE795_01320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE795_01325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE795_01335	COG0840	transmembrane signaling receptor activity
FE795_01340	COG2382	esterase
FE795_01345	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_01350	COG1535	isochorismatase
FE795_01350	COG3433	isochorismatase activity
FE795_01355	COG1169	isochorismate synthase
FE795_01370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE795_01375	COG3433	isochorismatase activity
FE795_01375	COG1535	isochorismatase
FE795_01380	COG1021	2,3-dihydroxybenzoate-AMP ligase
FE795_01395	COG0411	ABC transporter
FE795_01425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE795_01440	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE795_01460	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FE795_01465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE795_01475	COG0513	Belongs to the DEAD box helicase family
FE795_01480	COG2814	Major facilitator Superfamily
FE795_01500	COG1253	flavin adenine dinucleotide binding
FE795_01530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE795_01545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE795_01565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE795_01570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FE795_01580	COG0583	DNA-binding transcription factor activity
FE795_01585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_01590	COG1126	abc transporter atp-binding protein
FE795_01595	COG0765	amino acid transport
FE795_01600	COG0765	amino acid transport
FE795_01605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE795_01630	COG3391	amine dehydrogenase activity
FE795_01635	COG2259	Doxx family
FE795_01640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE795_01665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FE795_01670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE795_01675	COG0210	DNA helicase
FE795_01700	COG0067	glutamate synthase
FE795_01700	COG0069	glutamate synthase activity
FE795_01700	COG0070	glutamate synthase
FE795_01705	COG1024	Enoyl-CoA hydratase
FE795_01715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE795_01720	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE795_01745	COG2918	glutathione biosynthetic process
FE795_01755	COG2197	response regulator
FE795_01760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE795_01770	COG2223	nitrite transmembrane transporter activity
FE795_01775	COG2860	membrane
FE795_01780	COG1346	cytolysis
FE795_01790	COG0251	oxidation-reduction process
FE795_01795	COG0251	oxidation-reduction process
FE795_01810	COG0745	RESPONSE REGULATOR receiver
FE795_01820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE795_01835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FE795_01850	COG2096	Adenosyltransferase
FE795_01865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FE795_01870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FE795_01880	COG0523	cobalamin synthesis protein
FE795_01885	COG0735	belongs to the Fur family
FE795_01900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE795_01910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE795_01920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FE795_01925	COG1560	Kdo2-lipid A biosynthetic process
FE795_01935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FE795_01940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FE795_01945	COG1950	PFAM Membrane protein of
FE795_01950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FE795_01965	COG0617	tRNA 3'-terminal CCA addition
FE795_01980	COG0275	rRNA processing
FE795_01985	COG0730	response to heat
FE795_01990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FE795_01995	COG0129	dihydroxy-acid dehydratase activity
FE795_02000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE795_02005	COG0628	permease
FE795_02110	COG2826	transposase and inactivated derivatives, IS30 family
FE795_02135	COG4974	Belongs to the 'phage' integrase family
FE795_02175	COG3685	Protein conserved in bacteria
FE795_02190	COG0277	FAD linked oxidase domain protein
FE795_02195	COG1304	FMN binding
FE795_02200	COG2186	Transcriptional regulator
FE795_02215	COG2188	Transcriptional regulator
FE795_02220	COG1522	sequence-specific DNA binding
FE795_02230	COG1113	amino acid transport
FE795_02240	COG1349	DNA-binding transcription factor activity
FE795_02260	COG0395	ABC-type sugar transport system, permease component
FE795_02270	COG0861	Integral membrane protein TerC family
FE795_02275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE795_02285	COG1671	Belongs to the UPF0178 family
FE795_02295	COG1418	mRNA catabolic process
FE795_02305	COG4948	Mandelate Racemase Muconate Lactonizing
FE795_02320	COG0154	amidase activity
FE795_02330	COG0583	DNA-binding transcription factor activity
FE795_02355	COG0326	Molecular chaperone. Has ATPase activity
FE795_02360	COG4774	siderophore transport
FE795_02365	COG3128	pkhd-type hydroxylase
FE795_02375	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE795_02390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE795_02395	COG1652	LysM domain
FE795_02410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FE795_02425	COG0387	Pfam Sodium calcium exchanger
FE795_02440	COG0477	Major facilitator Superfamily
FE795_02445	COG0235	Class ii aldolase
FE795_02460	COG3391	amine dehydrogenase activity
FE795_02465	COG0590	tRNA wobble adenosine to inosine editing
FE795_02470	COG3257	ureidoglycine aminohydrolase activity
FE795_02475	COG0583	DNA-binding transcription factor activity
FE795_02480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FE795_02485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE795_02485	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE795_02495	COG0489	protein tyrosine kinase activity
FE795_02520	COG2081	HI0933 family
FE795_02525	COG0509	glycine decarboxylation via glycine cleavage system
FE795_02535	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FE795_02540	COG1765	OsmC-like protein
FE795_02545	COG3278	Belongs to the heme-copper respiratory oxidase family
FE795_02580	COG0469	pyruvate kinase activity
FE795_02585	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FE795_02595	COG2084	Dehydrogenase
FE795_02600	COG3622	Belongs to the hyi family
FE795_02605	COG3960	tartronate-semialdehyde synthase activity
FE795_02610	COG0583	DNA-binding transcription factor activity
FE795_02620	COG2233	PERMEase
FE795_02625	COG1942	4-Oxalocrotonate Tautomerase
FE795_02630	COG0235	Class ii aldolase
FE795_02635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FE795_02640	COG3195	allantoin biosynthetic process
FE795_02640	COG3648	Uricase
FE795_02650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE795_02655	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE795_02670	COG0438	transferase activity, transferring glycosyl groups
FE795_02680	COG0438	transferase activity, transferring glycosyl groups
FE795_02685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE795_02690	COG0277	FAD linked oxidase domain protein
FE795_02700	COG0179	Fumarylacetoacetate (FAA) hydrolase
FE795_02705	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FE795_02715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE795_02725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FE795_02750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE795_02755	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FE795_02760	COG0193	aminoacyl-tRNA hydrolase activity
FE795_02770	COG0012	GTP binding
FE795_02775	COG0582	viral genome integration into host DNA
FE795_02805	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FE795_02815	COG0732	type I restriction modification DNA specificity domain
FE795_02820	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FE795_02880	COG0288	reversible hydration of carbon dioxide
FE795_02885	COG0583	DNA-binding transcription factor activity
FE795_02895	COG4133	protoheme IX ABC transporter activity
FE795_02900	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE795_02915	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FE795_02925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE795_02930	COG3088	subunit of a heme lyase
FE795_02935	COG4235	cytochrome complex assembly
FE795_02940	COG0785	Cytochrome C biogenesis protein
FE795_02950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE795_02950	COG2169	Transcriptional regulator
FE795_02970	COG0559	Belongs to the binding-protein-dependent transport system permease family
FE795_02980	COG0411	ABC transporter
FE795_02990	COG1858	cytochrome C peroxidase
FE795_02995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE795_03000	COG1959	2 iron, 2 sulfur cluster binding
FE795_03005	COG2346	COG2346, Truncated hemoglobins
FE795_03050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FE795_03055	COG3383	formate dehydrogenase (NAD+) activity
FE795_03070	COG1910	domain protein
FE795_03075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE795_03080	COG0746	molybdenum cofactor guanylyltransferase activity
FE795_03085	COG0303	'Molybdopterin
FE795_03090	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE795_03095	COG0314	molybdopterin synthase activity
FE795_03105	COG0315	cyclic pyranopterin monophosphate synthase activity
FE795_03135	COG0678	peroxiredoxin activity
FE795_03150	COG0697	spore germination
FE795_03155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE795_03175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE795_03220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FE795_03225	COG4535	Mg2 and Co2 transporter CorC
FE795_03230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FE795_03235	COG1702	phosphate starvation-inducible protein PhoH
FE795_03240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE795_03255	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE795_03260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE795_03265	COG1862	Preprotein translocase
FE795_03270	COG0343	queuine tRNA-ribosyltransferase activity
FE795_03275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FE795_03280	COG2027	D-alanyl-D-alanine carboxypeptidase
FE795_03285	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FE795_03295	COG4575	ribosome binding
FE795_03310	COG0583	DNA-binding transcription factor activity
FE795_03325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE795_03340	COG0154	amidase activity
FE795_03350	COG0477	Major facilitator Superfamily
FE795_03360	COG0346	lactoylglutathione lyase activity
FE795_03365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FE795_03375	COG0436	Aminotransferase
FE795_03385	COG0280	phosphate acetyltransferase
FE795_03385	COG0281	malic enzyme
FE795_03395	COG2732	(Barnase) inhibitor
FE795_03400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE795_03405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE795_03410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE795_03415	COG0126	phosphoglycerate kinase activity
FE795_03435	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE795_03445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FE795_03455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FE795_03460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FE795_03465	COG0009	L-threonylcarbamoyladenylate synthase
FE795_03475	COG2030	dehydratase
FE795_03475	COG1012	belongs to the aldehyde dehydrogenase family
FE795_03480	COG1960	acyl-CoA dehydrogenase activity
FE795_03490	COG0405	Gamma-glutamyltransferase
FE795_03500	COG0579	oxidoreductase
FE795_03505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE795_03510	COG0259	pyridoxamine-phosphate oxidase activity
FE795_03520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE795_03535	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE795_03540	COG1215	transferase activity, transferring glycosyl groups
FE795_03550	COG0488	(ABC) transporter
FE795_03570	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FE795_03575	COG2894	cell division
FE795_03580	COG0850	regulation of cytokinetic process
FE795_03585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE795_03590	COG1271	oxidase subunit
FE795_03595	COG1294	oxidase, subunit
FE795_03600	COG0038	chloride channel
FE795_03610	COG0514	ATP-dependent DNA helicase (RecQ)
FE795_03615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE795_03620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE795_03625	COG0633	Ferredoxin
FE795_03630	COG0488	(ABC) transporter
FE795_03640	COG2001	Belongs to the MraZ family
FE795_03645	COG0275	rRNA processing
FE795_03650	COG3116	cell division
FE795_03660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FE795_03665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE795_03670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FE795_03680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FE795_03685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE795_03690	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE795_03695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FE795_03710	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FE795_03720	COG0739	heme binding
FE795_03720	COG0741	lytic transglycosylase activity
FE795_03720	COG1196	nuclear chromosome segregation
FE795_03725	COG0653	protein targeting
FE795_03735	COG2239	Acts as a magnesium transporter
FE795_03745	COG1473	amidohydrolase
FE795_03750	COG0318	PFAM AMP-dependent synthetase and ligase
FE795_03760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE795_03760	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FE795_03775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE795_03780	COG2011	ABC-type metal ion transport system permease component
FE795_03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_03795	COG0765	amino acid transport
FE795_03800	COG1126	abc transporter atp-binding protein
FE795_03820	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FE795_03825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE795_03830	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE795_03835	COG0700	Nucleoside recognition
FE795_03850	COG0204	Acyl-transferase
FE795_03855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE795_03860	COG0751	glycine-tRNA ligase activity
FE795_03865	COG0752	glycyl-tRNA synthetase alpha subunit
FE795_03895	COG1573	uracil-dna glycosylase
FE795_03905	COG0617	tRNA 3'-terminal CCA addition
FE795_03915	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE795_03920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FE795_03925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE795_03930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FE795_03935	COG0586	Pfam SNARE associated Golgi protein
FE795_03940	COG1477	protein flavinylation
FE795_03960	COG0860	N-Acetylmuramoyl-L-alanine amidase
FE795_03965	COG0802	atpase or kinase
FE795_03975	COG3181	Tripartite tricarboxylate transporter family receptor
FE795_03980	COG0281	malic enzyme
FE795_03980	COG0280	phosphate acetyltransferase
FE795_03985	COG0583	DNA-binding transcription factor activity
FE795_03990	COG1012	belongs to the aldehyde dehydrogenase family
FE795_03995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE795_04015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FE795_04040	COG1733	regulation of RNA biosynthetic process
FE795_04045	COG2910	NAD(P)H-binding
FE795_04050	COG2223	nitrite transmembrane transporter activity
FE795_04060	COG4974	Belongs to the 'phage' integrase family
FE795_04065	COG0725	ABC transporter, periplasmic molybdate-binding protein
FE795_04070	COG4149	molybdate abc transporter
FE795_04075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE795_04090	COG1074	ATP-dependent DNA helicase activity
FE795_04125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE795_04130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE795_04135	COG0505	Belongs to the CarA family
FE795_04140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE795_04160	COG2233	PERMEase
FE795_04165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE795_04170	COG1534	Rna-binding protein
FE795_04175	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FE795_04180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE795_04190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE795_04200	COG0248	Ppx GppA phosphatase
FE795_04205	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE795_04225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FE795_04230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE795_04280	COG1231	oxidoreductase activity
FE795_04290	COG2323	membrane
FE795_04300	COG1368	sulfuric ester hydrolase activity
FE795_04330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE795_04335	COG3327	negative regulation of DNA-templated transcription, initiation
FE795_04340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE795_04355	COG0009	L-threonylcarbamoyladenylate synthase
FE795_04360	COG1994	Peptidase M50
FE795_04365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE795_04370	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FE795_04375	COG1595	DNA-templated transcription, initiation
FE795_04385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FE795_04395	COG0156	8-amino-7-oxononanoate synthase activity
FE795_04400	COG2124	cytochrome p450
FE795_04405	COG3135	benzoate transporter
FE795_04410	COG2850	peptidyl-arginine hydroxylation
FE795_04415	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FE795_04440	COG0577	efflux transmembrane transporter activity
FE795_04440	COG1136	(ABC) transporter
FE795_04445	COG1538	Outer membrane efflux protein
FE795_04450	COG0363	glucosamine-6-phosphate deaminase activity
FE795_04455	COG1132	(ABC) transporter
FE795_04470	COG0583	DNA-binding transcription factor activity
FE795_04475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE795_04485	COG0668	transmembrane transport
FE795_04530	COG0154	amidase activity
FE795_04535	COG2031	fatty acid transporter
FE795_04545	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FE795_04550	COG0483	inositol monophosphate 1-phosphatase activity
FE795_04555	COG1253	flavin adenine dinucleotide binding
FE795_04580	COG0215	cysteine-tRNA ligase activity
FE795_04590	COG0825	malonyl-CoA metabolic process
FE795_04595	COG0037	tRNA processing
FE795_04620	COG0330	HflC and HflK could
FE795_04635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE795_04655	COG4208	sulfate ABC transporter
FE795_04660	COG3842	ATPase activity
FE795_04670	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FE795_04700	COG1304	FMN binding
FE795_04705	COG0435	Glutathione S-transferase
FE795_04710	COG0655	NAD(P)H dehydrogenase (quinone) activity
FE795_04725	COG2094	Belongs to the DNA glycosylase MPG family
FE795_04730	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE795_04735	COG2363	Small membrane protein
FE795_04740	COG0598	Magnesium transport protein CorA
FE795_04745	COG1960	acyl-CoA dehydrogenase activity
FE795_04755	COG0747	negative chemotaxis
FE795_04765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE795_04780	COG3284	Transcriptional regulator
FE795_04785	COG1012	belongs to the aldehyde dehydrogenase family
FE795_04790	COG1454	alcohol dehydrogenase
FE795_04795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE795_04835	COG3829	transcription factor binding
FE795_04840	COG0477	Major facilitator Superfamily
FE795_04850	COG0039	L-malate dehydrogenase activity
FE795_04855	COG2188	Transcriptional regulator
FE795_04860	COG2009	succinate dehydrogenase
FE795_04870	COG1053	succinate dehydrogenase
FE795_04875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE795_04880	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FE795_04885	COG0372	Belongs to the citrate synthase family
FE795_04890	COG2186	Transcriptional regulator
FE795_04895	COG1620	l-lactate permease
FE795_04900	COG0280	phosphate acetyltransferase
FE795_04900	COG0281	malic enzyme
FE795_04905	COG0567	Dehydrogenase, E1 component
FE795_04910	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE795_04915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE795_04920	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FE795_04935	COG2183	response to ionizing radiation
FE795_04940	COG1199	ATP-dependent helicase activity
FE795_04945	COG0659	secondary active sulfate transmembrane transporter activity
FE795_04955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE795_04955	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FE795_04960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FE795_04985	COG0564	pseudouridine synthase activity
FE795_04995	COG3243	poly(R)-hydroxyalkanoic acid synthase
FE795_05000	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_05005	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FE795_05030	COG3772	lysozyme
FE795_05125	COG3728	DNA packaging
FE795_05125	COG5484	DNA packaging
FE795_05135	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FE795_05230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE795_05235	COG1187	pseudouridine synthase activity
FE795_05240	COG0779	Required for maturation of 30S ribosomal subunits
FE795_05245	COG2251	uridine kinase activity
FE795_05245	COG0195	Participates in both transcription termination and antitermination
FE795_05250	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE795_05255	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FE795_05260	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FE795_05265	COG1217	gtp-binding protein TYPA
FE795_05270	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE795_05280	COG4160	amino acid transport
FE795_05290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_05305	COG1283	sodium-dependent phosphate transmembrane transporter activity
FE795_05310	COG0501	Belongs to the peptidase M48B family
FE795_05325	COG1722	exodeoxyribonuclease VII activity
FE795_05330	COG0142	geranyltranstransferase activity
FE795_05335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FE795_05340	COG1469	GTP cyclohydrolase I activity
FE795_05345	COG0360	Binds together with S18 to 16S ribosomal RNA
FE795_05350	COG2965	DNA replication, synthesis of RNA primer
FE795_05355	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FE795_05360	COG0359	binds to the 23S rRNA
FE795_05365	COG0305	Participates in initiation and elongation during chromosome replication
FE795_05375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FE795_05380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE795_05385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE795_05395	COG0436	Aminotransferase
FE795_05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FE795_05415	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FE795_05420	COG1562	ergosterol biosynthetic process
FE795_05425	COG1562	ergosterol biosynthetic process
FE795_05430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE795_05435	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_05460	COG3842	ATPase activity
FE795_05465	COG1176	ABC-type spermidine putrescine transport system, permease component I
FE795_05470	COG1177	transmembrane transport
FE795_05475	COG1393	Belongs to the ArsC family
FE795_05480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FE795_05485	COG0704	Plays a role in the regulation of phosphate uptake
FE795_05490	COG5001	Diguanylate cyclase
FE795_05490	COG3706	GGDEF domain
FE795_05490	COG2203	Gaf domain
FE795_05490	COG4251	negative regulation of phosphorylation
FE795_05495	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FE795_05500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE795_05500	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FE795_05505	COG1643	Atp-dependent helicase
FE795_05515	COG0438	transferase activity, transferring glycosyl groups
FE795_05520	COG0726	polysaccharide deacetylase
FE795_05535	COG0297	glycogen (starch) synthase activity
FE795_05540	COG0438	transferase activity, transferring glycosyl groups
FE795_05560	COG1132	(ABC) transporter
FE795_05610	COG2186	Transcriptional regulator
FE795_05615	COG0277	FAD linked oxidase domain protein
FE795_05620	COG0277	FAD linked oxidase domain protein
FE795_05625	COG0247	lactate metabolic process
FE795_05630	COG1012	belongs to the aldehyde dehydrogenase family
FE795_05635	COG4191	Histidine kinase
FE795_05655	COG2985	domain, Protein
FE795_05660	COG0076	glutamate decarboxylase activity
FE795_05675	COG0628	permease
FE795_05680	COG1283	sodium-dependent phosphate transmembrane transporter activity
FE795_05690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FE795_05700	COG0697	spore germination
FE795_05720	COG3094	Invasion gene expression up-regulator, SirB
FE795_05730	COG0640	Transcriptional regulator
FE795_05745	COG0789	Transcriptional regulator
FE795_05755	COG0659	secondary active sulfate transmembrane transporter activity
FE795_05760	COG2314	TM2 domain
FE795_05765	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE795_05770	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FE795_05775	COG0791	NLP P60 protein
FE795_05795	COG1360	Flagellar Motor Protein
FE795_05805	COG0835	chemotaxis
FE795_05810	COG0840	transmembrane signaling receptor activity
FE795_05815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FE795_05825	COG0745	RESPONSE REGULATOR receiver
FE795_05830	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FE795_05840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FE795_05855	COG2747	anti-sigma28 factor FlgM
FE795_05865	COG1815	bacterial-type flagellum-dependent cell motility
FE795_05870	COG1558	bacterial-type flagellum-dependent cell motility
FE795_05875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FE795_05880	COG1749	Flagellar hook protein flgE
FE795_05915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE795_05930	COG0840	transmembrane signaling receptor activity
FE795_05950	COG1987	bacterial-type flagellum assembly
FE795_05990	COG1157	protein secretion by the type III secretion system
FE795_06005	COG1766	The M ring may be actively involved in energy transduction
FE795_06010	COG1677	Flagellar hook-basal body complex protein FliE
FE795_06015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FE795_06040	COG1334	flagellar protein FlaG
FE795_06045	COG1191	sigma factor activity
FE795_06050	COG2161	toxin-antitoxin pair type II binding
FE795_06055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FE795_06105	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE795_06125	COG2733	membrane
FE795_06130	COG0840	transmembrane signaling receptor activity
FE795_06135	COG0840	transmembrane signaling receptor activity
FE795_06150	COG3181	Tripartite tricarboxylate transporter family receptor
FE795_06160	COG2610	gluconate transmembrane transporter activity
FE795_06170	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_06180	COG2824	Alkylphosphonate utilization operon protein PhnA
FE795_06195	COG4771	TonB-dependent receptor
FE795_06200	COG1858	cytochrome C peroxidase
FE795_06210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_06220	COG1113	amino acid transport
FE795_06235	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE795_06260	COG1278	Cold shock
FE795_06265	COG0642	Histidine kinase
FE795_06275	COG3278	Belongs to the heme-copper respiratory oxidase family
FE795_06285	COG2863	cytochrome
FE795_06290	COG3258	Cytochrome c
FE795_06300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE795_06325	COG0025	NhaP-type Na H and K H
FE795_06340	COG1289	transmembrane transporter activity
FE795_06345	COG2252	PERMEase
FE795_06365	COG1999	signal sequence binding
FE795_06380	COG0069	glutamate synthase activity
FE795_06390	COG1846	Transcriptional regulator
FE795_06400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FE795_06440	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_06450	COG1012	belongs to the aldehyde dehydrogenase family
FE795_06455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE795_06460	COG1511	domain protein
FE795_06460	COG3264	Mechanosensitive ion channel
FE795_06465	COG1511	domain protein
FE795_06465	COG3264	Mechanosensitive ion channel
FE795_06485	COG1396	sequence-specific DNA binding
FE795_06490	COG3437	response regulator, receiver
FE795_06495	COG0784	Response regulator, receiver
FE795_06495	COG2198	Histidine kinase
FE795_06495	COG2205	protein histidine kinase activity
FE795_06500	COG2239	Acts as a magnesium transporter
FE795_06515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE795_06520	COG1490	D-aminoacyl-tRNA deacylase activity
FE795_06525	COG2076	Multidrug Resistance protein
FE795_06535	COG0456	acetyltransferase
FE795_06545	COG0501	Belongs to the peptidase M48B family
FE795_06605	COG2199	diguanylate cyclase activity
FE795_06620	COG1522	sequence-specific DNA binding
FE795_06625	COG0626	cystathionine gamma-synthase activity
FE795_06635	COG0494	nUDIX hydrolase
FE795_06640	COG2832	Protein of unknown function (DUF454)
FE795_06650	COG0137	argininosuccinate synthase activity
FE795_06655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FE795_06660	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE795_06680	COG1609	Transcriptional regulator
FE795_06685	COG0519	Catalyzes the synthesis of GMP from XMP
FE795_06685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE795_06695	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FE795_06705	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FE795_06710	COG2205	protein histidine kinase activity
FE795_06715	COG0745	RESPONSE REGULATOR receiver
FE795_06720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE795_06730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE795_06735	COG0268	Binds directly to 16S ribosomal RNA
FE795_06740	COG0728	peptidoglycan biosynthetic process
FE795_06750	COG0563	adenylate kinase activity
FE795_06755	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FE795_06760	COG2835	tetraacyldisaccharide 4'-kinase activity
FE795_06770	COG0848	biopolymer transport protein
FE795_06775	COG0811	peptide transport
FE795_06780	COG1570	exodeoxyribonuclease VII activity
FE795_06785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE795_06795	COG0183	Belongs to the thiolase family
FE795_06805	COG1278	Cold shock
FE795_06810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FE795_06815	COG0542	response to heat
FE795_06820	COG2995	paraquat-inducible protein a
FE795_06825	COG3008	intermembrane lipid transfer
FE795_06845	COG0559	Belongs to the binding-protein-dependent transport system permease family
FE795_06905	COG5001	Diguanylate cyclase
FE795_06905	COG4251	negative regulation of phosphorylation
FE795_06905	COG2203	Gaf domain
FE795_06905	COG3706	GGDEF domain
FE795_06910	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FE795_06915	COG0756	dUTP diphosphatase activity
FE795_06925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE795_06930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FE795_06935	COG0196	riboflavin kinase activity
FE795_06940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE795_06945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FE795_06945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE795_06955	COG0210	DNA helicase
FE795_06980	COG0488	(ABC) transporter
FE795_06985	COG2890	protein-(glutamine-N5) methyltransferase activity
FE795_06990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE795_06995	COG2171	N-acyltransferase activity
FE795_07010	COG0471	metal ion transport
FE795_07010	COG3273	potassium ion transport
FE795_07060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE795_07065	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE795_07070	COG0740	serine-type endopeptidase activity
FE795_07080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FE795_07085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE795_07100	COG0556	nucleotide-excision repair
FE795_07105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE795_07115	COG1104	cysteine desulfurase activity
FE795_07125	COG0316	Belongs to the HesB IscA family
FE795_07135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FE795_07140	COG4221	oxidoreductase activity
FE795_07155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FE795_07160	COG0697	spore germination
FE795_07165	COG0385	Bile acid
FE795_07175	COG2831	hemolysin activation secretion protein
FE795_07205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE795_07220	COG1136	(ABC) transporter
FE795_07225	COG0084	hydrolase, TatD family'
FE795_07240	COG0613	PHP domain protein
FE795_07250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FE795_07250	COG0047	phosphoribosylformylglycinamidine synthase activity
FE795_07265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE795_07265	COG0519	Catalyzes the synthesis of GMP from XMP
FE795_07270	COG0583	DNA-binding transcription factor activity
FE795_07285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FE795_07295	COG1960	acyl-CoA dehydrogenase activity
FE795_07300	COG0523	cobalamin synthesis protein
FE795_07305	COG1469	GTP cyclohydrolase I activity
FE795_07310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FE795_07320	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FE795_07325	COG0735	belongs to the Fur family
FE795_07330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE795_07345	COG3852	Histidine kinase
FE795_07350	COG0745	RESPONSE REGULATOR receiver
FE795_07360	COG1017	nitric oxide dioxygenase activity
FE795_07380	COG0583	DNA-binding transcription factor activity
FE795_07385	COG1276	copper resistance
FE795_07385	COG2372	response to copper ion
FE795_07400	COG0740	serine-type endopeptidase activity
FE795_07415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE795_07420	COG0640	Transcriptional regulator
FE795_07450	COG3485	protocatechuate 3,4-dioxygenase
FE795_07460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE795_07465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE795_07475	COG3135	benzoate transporter
FE795_07480	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FE795_07495	COG4555	ABC transporter
FE795_07505	COG2197	response regulator
FE795_07535	COG1846	Transcriptional regulator
FE795_07540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE795_07545	COG2271	Major facilitator Superfamily
FE795_07555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE795_07565	COG0697	spore germination
FE795_07590	COG3842	ATPase activity
FE795_07620	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FE795_07625	COG0667	Aldo Keto reductase
FE795_07640	COG0582	viral genome integration into host DNA
FE795_07645	COG1278	Cold shock
FE795_07655	COG1272	protein, Hemolysin III
FE795_07660	COG3422	double-strand break repair
FE795_07670	COG0477	Major facilitator Superfamily
FE795_07675	COG0154	amidase activity
FE795_07690	COG3040	lipid binding
FE795_07695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_07700	COG0765	amino acid transport
FE795_07705	COG0765	amino acid transport
FE795_07710	COG1126	abc transporter atp-binding protein
FE795_07755	COG2871	sodium ion transport
FE795_07795	COG2814	Major facilitator Superfamily
FE795_07800	COG1280	lysine exporter protein (LysE YggA)
FE795_07830	COG0330	HflC and HflK could
FE795_07840	COG2226	methyltransferase
FE795_07860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE795_07875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FE795_07880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE795_07895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE795_07900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE795_07930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FE795_07935	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FE795_07940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE795_07945	COG0072	phenylalanine-tRNA ligase activity
FE795_07945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE795_07960	COG2833	Protein of unknown function (DUF455)
FE795_07970	COG5265	(ABC) transporter
FE795_07975	COG1959	2 iron, 2 sulfur cluster binding
FE795_07980	COG0719	Fe-S assembly protein
FE795_07985	COG0396	ATPase activity
FE795_07990	COG0719	Fe-S assembly protein
FE795_08000	COG0822	iron-sulfur transferase activity
FE795_08005	COG2151	metal-sulfur cluster biosynthetic enzyme
FE795_08040	COG1215	transferase activity, transferring glycosyl groups
FE795_08045	COG1649	PFAM Uncharacterised BCR, COG1649
FE795_08045	COG0726	polysaccharide deacetylase
FE795_08050	COG0457	Tetratricopeptide repeat
FE795_08210	COG5410	chromosome segregation
FE795_08285	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE795_08290	COG3657	addiction module killer protein
FE795_08390	COG3949	Membrane
FE795_08405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE795_08420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE795_08425	COG0569	domain protein
FE795_08430	COG1902	pentaerythritol trinitrate reductase activity
FE795_08440	COG1610	YqeY-like protein
FE795_08445	COG0587	DNA-directed DNA polymerase activity
FE795_08485	COG0583	DNA-binding transcription factor activity
FE795_08490	COG1686	Belongs to the peptidase S11 family
FE795_08505	COG1360	Flagellar Motor Protein
FE795_08515	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_08525	COG4221	oxidoreductase activity
FE795_08530	COG0307	riboflavin synthase, alpha
FE795_08545	COG1301	dicarboxylic acid transport
FE795_08550	COG4191	Histidine kinase
FE795_08595	COG2233	PERMEase
FE795_08605	COG1473	amidohydrolase
FE795_08615	COG1846	Transcriptional regulator
FE795_08620	COG2816	NAD+ diphosphatase activity
FE795_08625	COG1561	YicC-like family, N-terminal region
FE795_08640	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FE795_08645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FE795_08650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE795_08655	COG0174	glutamine synthetase
FE795_08660	COG2153	protein acetylation
FE795_08665	COG3842	ATPase activity
FE795_08670	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE795_08675	COG1840	ABC-type Fe3 transport system, periplasmic component
FE795_08690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE795_08700	COG0783	Belongs to the Dps family
FE795_08710	COG3842	ATPase activity
FE795_08715	COG0395	ABC-type sugar transport system, permease component
FE795_08725	COG1653	transport
FE795_08740	COG0559	Belongs to the binding-protein-dependent transport system permease family
FE795_08760	COG0625	glutathione transferase activity
FE795_08770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE795_08775	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_08780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE795_08785	COG0114	fumarate hydratase activity
FE795_08790	COG2133	pyrroloquinoline quinone binding
FE795_08795	COG0589	response to stress
FE795_08805	COG2807	transmembrane transport
FE795_08815	COG0583	DNA-binding transcription factor activity
FE795_08835	COG4974	Belongs to the 'phage' integrase family
FE795_09010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE795_09045	COG0840	transmembrane signaling receptor activity
FE795_09080	COG0697	spore germination
FE795_09090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FE795_09165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE795_09170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE795_09190	COG2003	Belongs to the UPF0758 family
FE795_09245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE795_09300	COG2894	cell division
FE795_09445	COG3038	cytochrome b561
FE795_09455	COG2353	YceI-like domain
FE795_09460	COG1393	Belongs to the ArsC family
FE795_09465	COG0625	glutathione transferase activity
FE795_09485	COG0084	hydrolase, TatD family'
FE795_09490	COG0470	DNA polymerase III
FE795_09500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE795_09505	COG0354	folic acid binding
FE795_09520	COG1960	acyl-CoA dehydrogenase activity
FE795_09525	COG2914	Belongs to the UPF0125 (RnfH) family
FE795_09530	COG2867	negative regulation of translational initiation
FE795_09535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE795_09540	COG1252	NADH dehydrogenase
FE795_09560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE795_09565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FE795_09570	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE795_09580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE795_09585	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE795_09595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE795_09605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE795_09610	COG0575	Belongs to the CDS family
FE795_09615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE795_09620	COG0233	cytoplasmic translational termination
FE795_09625	COG0528	UMP kinase activity
FE795_09630	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FE795_09635	COG0052	Belongs to the universal ribosomal protein uS2 family
FE795_09640	COG0024	Methionine aminopeptidase
FE795_09645	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FE795_09665	COG1286	toxin biosynthetic process
FE795_09675	COG0285	dihydrofolate synthase activity
FE795_09680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE795_09685	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE795_09690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FE795_09700	COG4566	intracellular signal transduction
FE795_09705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE795_09715	COG1999	signal sequence binding
FE795_09735	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE795_09745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE795_09750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE795_09755	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FE795_09775	COG0183	Belongs to the thiolase family
FE795_09795	COG0583	DNA-binding transcription factor activity
FE795_09820	COG0194	GDP metabolic process
FE795_09825	COG1758	RNA polymerase activity
FE795_09830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE795_09840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FE795_09845	COG0739	heme binding
FE795_09850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE795_09855	COG0584	glycerophosphoryl diester phosphodiesterase
FE795_09860	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FE795_09865	COG1187	pseudouridine synthase activity
FE795_09870	COG3161	chorismate lyase activity
FE795_09875	COG2814	Major facilitator Superfamily
FE795_09880	COG0656	L-ascorbic acid biosynthetic process
FE795_09890	COG0668	transmembrane transport
FE795_09895	COG0165	Argininosuccinate lyase
FE795_09900	COG1846	Transcriptional regulator
FE795_09900	COG1940	carbohydrate kinase activity
FE795_09910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE795_09920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE795_09930	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE795_09935	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FE795_09940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FE795_09945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FE795_09950	COG2252	PERMEase
FE795_09955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE795_09975	COG0488	(ABC) transporter
FE795_09980	COG1619	proteins homologs of microcin C7 resistance protein MccF
FE795_09990	COG1131	(ABC) transporter
FE795_09995	COG0842	Transport permease protein
FE795_10010	COG0697	spore germination
FE795_10030	COG1666	GTP binding
FE795_10035	COG0318	PFAM AMP-dependent synthetase and ligase
FE795_10040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE795_10045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE795_10045	COG0519	Catalyzes the synthesis of GMP from XMP
FE795_10050	COG2207	Transcriptional regulator
FE795_10060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE795_10065	COG0135	phosphoribosylanthranilate isomerase activity
FE795_10070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_10080	COG0101	tRNA pseudouridine synthase activity
FE795_10090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE795_10095	COG0473	3-isopropylmalate dehydrogenase activity
FE795_10115	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FE795_10120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FE795_10130	COG1295	ribonuclease BN
FE795_10140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE795_10145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FE795_10170	COG4964	Belongs to the GSP D family
FE795_10215	COG2959	enzyme of heme biosynthesis
FE795_10225	COG0181	hydroxymethylbilane synthase activity
FE795_10230	COG0861	Integral membrane protein TerC family
FE795_10235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FE795_10240	COG0045	succinate-CoA ligase (ADP-forming) activity
FE795_10250	COG0583	DNA-binding transcription factor activity
FE795_10255	COG2137	regulation of response to DNA damage stimulus
FE795_10260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE795_10275	COG0477	Major facilitator Superfamily
FE795_10290	COG0318	PFAM AMP-dependent synthetase and ligase
FE795_10295	COG1024	Enoyl-CoA hydratase
FE795_10300	COG3162	membrane
FE795_10305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE795_10315	COG0540	Belongs to the ATCase OTCase family
FE795_10330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE795_10350	COG2070	2-Nitropropane dioxygenase
FE795_10355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE795_10360	COG2111	Na H antiporter
FE795_10360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE795_10365	COG1006	Multisubunit Na H antiporter MnhC subunit
FE795_10370	COG0651	ATP synthesis coupled electron transport
FE795_10380	COG2212	antiporter activity
FE795_10395	COG3158	transport of potassium into the cell
FE795_10400	COG0642	Histidine kinase
FE795_10425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE795_10430	COG4208	sulfate ABC transporter
FE795_10435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE795_10440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FE795_10450	COG1278	Cold shock
FE795_10470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE795_10470	COG1648	precorrin-2 dehydrogenase activity
FE795_10475	COG2010	Cytochrome c
FE795_10485	COG1522	sequence-specific DNA binding
FE795_10500	COG0535	radical SAM domain protein
FE795_10505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE795_10505	COG1648	precorrin-2 dehydrogenase activity
FE795_10515	COG2010	Cytochrome c
FE795_10520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE795_10530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE795_10535	COG0557	exoribonuclease II activity
FE795_10560	COG2375	cellular response to nickel ion
FE795_10590	COG0583	DNA-binding transcription factor activity
FE795_10595	COG3842	ATPase activity
FE795_10605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE795_10610	COG1840	ABC-type Fe3 transport system, periplasmic component
FE795_10630	COG0412	Dienelactone hydrolase
FE795_10635	COG3530	Putative quorum-sensing-regulated virulence factor
FE795_10640	COG0625	glutathione transferase activity
FE795_10645	COG1741	Belongs to the pirin family
FE795_10655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE795_10660	COG2814	Major facilitator Superfamily
FE795_10665	COG2807	transmembrane transport
FE795_10670	COG2207	Transcriptional regulator
FE795_10675	COG3135	benzoate transporter
FE795_10710	COG0402	S-adenosylhomocysteine deaminase activity
FE795_10720	COG0745	RESPONSE REGULATOR receiver
FE795_10725	COG2205	protein histidine kinase activity
FE795_10740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FE795_10745	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FE795_10750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE795_10755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FE795_10760	COG0330	HflC and HflK could
FE795_10765	COG0330	HflC and HflK could
FE795_10770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE795_10775	COG1923	regulation of RNA biosynthetic process
FE795_10785	COG1160	GTP binding
FE795_10790	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE795_10795	COG2976	Protein conserved in bacteria
FE795_10815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FE795_10820	COG0105	UTP biosynthetic process
FE795_10830	COG0336	Belongs to the RNA methyltransferase TrmD family
FE795_10840	COG0228	four-way junction DNA binding
FE795_10845	COG0425	Belongs to the sulfur carrier protein TusA family
FE795_10850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE795_10865	COG2351	hydroxyisourate hydrolase activity
FE795_10895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE795_10920	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FE795_10925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FE795_10950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE795_10955	COG0601	transmembrane transport
FE795_10985	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FE795_10990	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE795_10995	COG0542	response to heat
FE795_11000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE795_11015	COG0348	domain, Protein
FE795_11035	COG3278	Belongs to the heme-copper respiratory oxidase family
FE795_11045	COG2217	Heavy metal translocating P-type atpase
FE795_11050	COG2224	Isocitrate lyase
FE795_11055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE795_11055	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE795_11075	COG1472	Belongs to the glycosyl hydrolase 3 family
FE795_11080	COG0736	holo-[acyl-carrier-protein] synthase activity
FE795_11090	COG2050	protein possibly involved in aromatic compounds catabolism
FE795_11095	COG1024	Enoyl-CoA hydratase
FE795_11100	COG1012	belongs to the aldehyde dehydrogenase family
FE795_11105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE795_11110	COG2151	metal-sulfur cluster biosynthetic enzyme
FE795_11115	COG3396	Phenylacetate-CoA oxygenase
FE795_11120	COG3460	Phenylacetate-CoA oxygenase
FE795_11125	COG3396	Phenylacetate-CoA oxygenase
FE795_11130	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FE795_11135	COG0501	Belongs to the peptidase M48B family
FE795_11140	COG1162	GTPase activity
FE795_11150	COG0335	large ribosomal subunit rRNA binding
FE795_11170	COG0450	alkyl hydroperoxide reductase
FE795_11175	COG1960	acyl-CoA dehydrogenase activity
FE795_11190	COG0123	including yeast histone deacetylase and acetoin utilization protein
FE795_11195	COG2951	lytic endotransglycosylase activity
FE795_11210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE795_11215	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FE795_11220	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FE795_11240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE795_11245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE795_11250	COG0287	Prephenate dehydrogenase
FE795_11260	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE795_11275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE795_11295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE795_11315	COG0753	catalase activity
FE795_11325	COG4335	DNA alkylation repair
FE795_11335	COG0436	Aminotransferase
FE795_11345	COG0251	oxidation-reduction process
FE795_11360	COG0625	glutathione transferase activity
FE795_11370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE795_11375	COG0697	spore germination
FE795_11390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE795_11405	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FE795_11410	COG1280	lysine exporter protein (LysE YggA)
FE795_11430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE795_11440	COG2205	protein histidine kinase activity
FE795_11440	COG0784	Response regulator, receiver
FE795_11440	COG2198	Histidine kinase
FE795_11445	COG2046	Belongs to the sulfate adenylyltransferase family
FE795_11450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FE795_11465	COG0840	transmembrane signaling receptor activity
FE795_11470	COG2119	membrane
FE795_11485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE795_11490	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE795_11505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE795_11510	COG2321	neutral zinc metallopeptidase
FE795_11520	COG0347	Belongs to the P(II) protein family
FE795_11525	COG0004	ammonium transporteR
FE795_11530	COG3909	cytochrome
FE795_11540	COG0625	glutathione transferase activity
FE795_11555	COG0730	response to heat
FE795_11560	COG0482	sulfurtransferase activity
FE795_11565	COG0277	FAD linked oxidase domain protein
FE795_11570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE795_11575	COG2879	small protein
FE795_11580	COG1966	Carbon starvation protein
FE795_11585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_11590	COG0765	amino acid transport
FE795_11595	COG0765	amino acid transport
FE795_11600	COG1126	abc transporter atp-binding protein
FE795_11605	COG5285	phytanoyl-CoA dioxygenase
FE795_11610	COG0662	Cupin 2, conserved barrel domain protein
FE795_11620	COG0456	acetyltransferase
FE795_11625	COG1846	Transcriptional regulator
FE795_11635	COG0312	modulator of DNA gyrase
FE795_11650	COG0308	aminopeptidase N
FE795_11655	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FE795_11670	COG0473	3-isopropylmalate dehydrogenase activity
FE795_11675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE795_11680	COG0433	COG0433 Predicted ATPase
FE795_11685	COG0217	transcriptional regulatory protein
FE795_11690	COG0151	Belongs to the GarS family
FE795_11700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE795_11705	COG0799	negative regulation of ribosome biogenesis
FE795_11710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FE795_11715	COG0424	maF-like protein
FE795_11735	COG0023	Translation Initiation Factor
FE795_11745	COG2084	Dehydrogenase
FE795_11750	COG0625	glutathione transferase activity
FE795_11755	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FE795_11760	COG1047	Peptidyl-prolyl cis-trans
FE795_11765	COG2003	Belongs to the UPF0758 family
FE795_11770	COG1737	Transcriptional regulator
FE795_11775	COG0477	Major facilitator Superfamily
FE795_11785	COG2271	Major facilitator Superfamily
FE795_11790	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FE795_11805	COG0534	Mate efflux family protein
FE795_11810	COG4175	Glycine betaine
FE795_11815	COG4176	ABC-type proline glycine betaine transport system permease component
FE795_11825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE795_11830	COG2814	Major facilitator Superfamily
FE795_11835	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE795_11840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE795_11845	COG0495	leucyl-tRNA aminoacylation
FE795_11855	COG1466	dna polymerase III delta subunit
FE795_11860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FE795_11865	COG1981	membrane
FE795_11880	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FE795_11890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FE795_11895	COG0148	phosphopyruvate hydratase activity
FE795_11905	COG2814	Major facilitator Superfamily
FE795_11920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FE795_11925	COG0504	CTP synthase activity
FE795_11955	COG0697	spore germination
FE795_11960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE795_11970	COG0791	NLP P60 protein
FE795_11980	COG0583	DNA-binding transcription factor activity
FE795_11990	COG0583	DNA-binding transcription factor activity
FE795_12000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FE795_12015	COG1045	serine acetyltransferase
FE795_12030	COG1381	Involved in DNA repair and RecF pathway recombination
FE795_12035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FE795_12040	COG0571	ribonuclease III activity
FE795_12055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE795_12075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE795_12080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE795_12085	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_12090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FE795_12095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE795_12105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FE795_12110	COG1399	metal-binding, possibly nucleic acid-binding protein
FE795_12115	COG0424	maF-like protein
FE795_12125	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE795_12130	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FE795_12135	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FE795_12140	COG0546	phosphoglycolate phosphatase activity
FE795_12150	COG1530	ribonuclease E activity
FE795_12155	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FE795_12165	COG0133	tryptophan synthase activity
FE795_12170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE795_12180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FE795_12185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE795_12195	COG2878	Part of a membrane complex involved in electron transport
FE795_12200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE795_12205	COG1129	ABC transporter
FE795_12210	COG3047	cAMP biosynthetic process
FE795_12235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE795_12240	COG2917	probably involved in intracellular septation
FE795_12250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE795_12255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE795_12265	COG1196	nuclear chromosome segregation
FE795_12270	COG0477	Major facilitator Superfamily
FE795_12275	COG1573	uracil-dna glycosylase
FE795_12280	COG1214	PFAM Peptidase M22, glycoprotease
FE795_12295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FE795_12300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FE795_12305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE795_12310	COG0560	Phosphoserine phosphatase
FE795_12315	COG2070	2-Nitropropane dioxygenase
FE795_12325	COG1007	ATP synthesis coupled electron transport
FE795_12340	COG0713	ATP synthesis coupled electron transport
FE795_12350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE795_12355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE795_12375	COG0649	NAD binding
FE795_12380	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE795_12385	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE795_12390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE795_12395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FE795_12410	COG0149	triose-phosphate isomerase activity
FE795_12415	COG0604	alcohol dehydrogenase
FE795_12415	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_12415	COG3321	synthase
FE795_12430	COG1185	polyribonucleotide nucleotidyltransferase activity
FE795_12435	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE795_12440	COG1183	phosphatidylcholine synthase activity
FE795_12445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FE795_12450	COG0440	acetolactate synthase activity
FE795_12455	COG0028	Belongs to the TPP enzyme family
FE795_12460	COG1289	transmembrane transporter activity
FE795_12465	COG3022	response to hydroperoxide
FE795_12470	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_12490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE795_12495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE795_12500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FE795_12505	COG1674	ftsk spoiiie
FE795_12510	COG0492	ferredoxin-NADP+ reductase activity
FE795_12530	COG0477	Major facilitator Superfamily
FE795_12550	COG2272	Belongs to the type-B carboxylesterase lipase family
FE795_12555	COG1960	acyl-CoA dehydrogenase activity
FE795_12580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE795_12600	COG2204	response regulator
FE795_12640	COG4964	Belongs to the GSP D family
FE795_12700	COG0612	Peptidase, M16
FE795_12705	COG0484	heat shock protein binding
FE795_12710	COG0443	Heat shock 70 kDa protein
FE795_12715	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FE795_12720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FE795_12730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FE795_12735	COG0497	DNA recombination
FE795_12740	COG0735	belongs to the Fur family
FE795_12745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE795_12775	COG0477	Major facilitator Superfamily
FE795_12800	COG5001	Diguanylate cyclase
FE795_12800	COG3300	MHYT domain
FE795_12815	COG2819	hydrolase of the alpha beta superfamily
FE795_12820	COG1454	alcohol dehydrogenase
FE795_12855	COG1414	Transcriptional regulator
FE795_12860	COG0513	Belongs to the DEAD box helicase family
FE795_12865	COG0583	DNA-binding transcription factor activity
FE795_12870	COG4638	Rieske (2fe-2S)
FE795_12875	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE795_12890	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE795_12905	COG3971	2-oxopent-4-enoate hydratase activity
FE795_12910	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FE795_12915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE795_12920	COG2814	Major facilitator Superfamily
FE795_12935	COG0154	amidase activity
FE795_12950	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_12960	COG0842	Transport permease protein
FE795_12965	COG0842	Transport permease protein
FE795_12965	COG1129	ABC transporter
FE795_12970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE795_12980	COG3243	poly(R)-hydroxyalkanoic acid synthase
FE795_12990	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FE795_12995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FE795_13005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE795_13020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE795_13035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FE795_13040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FE795_13060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE795_13175	COG0517	IMP dehydrogenase activity
FE795_13175	COG0516	GMP reductase activity
FE795_13185	COG1027	Aspartate ammonia-lyase
FE795_13190	COG1846	Transcriptional regulator
FE795_13200	COG0494	nUDIX hydrolase
FE795_13205	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FE795_13210	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FE795_13225	COG1414	Transcriptional regulator
FE795_13245	COG0513	Belongs to the DEAD box helicase family
FE795_13265	COG0429	hydrolase of the alpha beta-hydrolase fold
FE795_13290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE795_13300	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FE795_13305	COG0138	bifunctional purine biosynthesis protein purh
FE795_13310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FE795_13315	COG0632	four-way junction helicase activity
FE795_13325	COG2255	four-way junction helicase activity
FE795_13335	COG0418	dihydroorotase activity
FE795_13345	COG0415	Belongs to the DNA photolyase family
FE795_13385	COG2897	thiosulfate sulfurtransferase activity
FE795_13405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE795_13410	COG4654	Cytochrome c, class I
FE795_13445	COG1177	transmembrane transport
FE795_13450	COG3842	ATPase activity
FE795_13455	COG1840	ABC-type Fe3 transport system, periplasmic component
FE795_13460	COG2084	Dehydrogenase
FE795_13475	COG0494	nUDIX hydrolase
FE795_13480	COG0442	prolyl-tRNA aminoacylation
FE795_13485	COG0824	Thioesterase
FE795_13490	COG0811	peptide transport
FE795_13495	COG0848	biopolymer transport protein
FE795_13505	COG0823	Involved in the tonB-independent uptake of proteins
FE795_13520	COG0596	Alpha beta hydrolase
FE795_13545	COG1079	Belongs to the binding-protein-dependent transport system permease family
FE795_13550	COG4603	Belongs to the binding-protein-dependent transport system permease family
FE795_13555	COG3845	ABC transporter
FE795_13575	COG0427	acetyl-CoA hydrolase
FE795_13580	COG0583	DNA-binding transcription factor activity
FE795_13590	COG3634	alkyl hydroperoxide reductase activity
FE795_13605	COG0697	spore germination
FE795_13610	COG0175	sulfate reduction
FE795_13620	COG2895	sulfate adenylyltransferase (ATP) activity
FE795_13630	COG1012	belongs to the aldehyde dehydrogenase family
FE795_13635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE795_13640	COG5383	Protein conserved in bacteria
FE795_13650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FE795_13665	COG0583	DNA-binding transcription factor activity
FE795_13670	COG1741	Belongs to the pirin family
FE795_13675	COG3706	GGDEF domain
FE795_13680	COG0154	amidase activity
FE795_13685	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FE795_13695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FE795_13700	COG0284	orotidine-5'-phosphate decarboxylase activity
FE795_13715	COG1414	Transcriptional regulator
FE795_13725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FE795_13735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE795_13740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FE795_13765	COG0742	ribosomal rna small subunit methyltransferase
FE795_13770	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FE795_13775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE795_13805	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FE795_13820	COG1335	isochorismatase
FE795_13825	COG2309	aminopeptidase activity
FE795_13830	COG0596	Alpha beta hydrolase
FE795_13835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE795_13835	COG2010	Cytochrome c
FE795_13840	COG2080	2 iron, 2 sulfur cluster binding
FE795_13845	COG2010	Cytochrome c
FE795_13845	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE795_13860	COG0411	ABC transporter
FE795_13900	COG3181	Tripartite tricarboxylate transporter family receptor
FE795_13910	COG1234	tRNA 3'-trailer cleavage
FE795_13915	COG2188	Transcriptional regulator
FE795_13925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE795_13935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE795_13935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE795_13940	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FE795_13940	COG3608	succinylglutamate desuccinylase aspartoacylase
FE795_13945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FE795_13970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FE795_13995	COG1335	isochorismatase
FE795_14000	COG2309	aminopeptidase activity
FE795_14005	COG0596	Alpha beta hydrolase
FE795_14020	COG2031	fatty acid transporter
FE795_14035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE795_14040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE795_14045	COG0328	RNA-DNA hybrid ribonuclease activity
FE795_14050	COG2226	methyltransferase
FE795_14055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE795_14060	COG0741	lytic transglycosylase activity
FE795_14060	COG1388	LysM domain
FE795_14070	COG2204	response regulator
FE795_14075	COG4191	Histidine kinase
FE795_14080	COG1301	dicarboxylic acid transport
FE795_14090	COG1054	Belongs to the UPF0176 family
FE795_14110	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE795_14125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FE795_14130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FE795_14145	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_14150	COG1877	trehalose-phosphatase activity
FE795_14185	COG0604	alcohol dehydrogenase
FE795_14195	COG1024	Enoyl-CoA hydratase
FE795_14215	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FE795_14255	COG1393	Belongs to the ArsC family
FE795_14260	COG0431	NADPH-dependent FMN reductase
FE795_14275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE795_14275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE795_14280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE795_14285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE795_14290	COG1881	PFAM PEBP family protein
FE795_14295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE795_14300	COG0739	heme binding
FE795_14305	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FE795_14310	COG0316	Belongs to the HesB IscA family
FE795_14320	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FE795_14325	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE795_14330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FE795_14335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FE795_14340	COG0312	modulator of DNA gyrase
FE795_14345	COG3028	Belongs to the UPF0307 family
FE795_14375	COG4566	intracellular signal transduction
FE795_14380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE795_14420	COG0762	integral membrane protein
FE795_14425	COG2169	Transcriptional regulator
FE795_14425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE795_14430	COG3133	Outer membrane lipoprotein
FE795_14435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE795_14450	COG0439	Biotin carboxylase
FE795_14455	COG0511	ligase activity, forming carbon-carbon bonds
FE795_14460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FE795_14465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE795_14470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE795_14475	COG3150	esterase
FE795_14490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FE795_14495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE795_14505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE795_14520	COG1678	Uncharacterized ACR, COG1678
FE795_14535	COG0352	thiamine-phosphate diphosphorylase activity
FE795_14540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FE795_14555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FE795_14565	COG3237	CsbD-like
FE795_14570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FE795_14575	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FE795_14580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE795_14585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FE795_14610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FE795_14625	COG1126	abc transporter atp-binding protein
FE795_14630	COG0765	amino acid transport
FE795_14635	COG4597	amino acid ABC transporter
FE795_14640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE795_14645	COG2884	Cell division ATP-binding protein ftsE
FE795_14650	COG2177	Part of the ABC transporter FtsEX involved in
FE795_14655	COG1194	a g-specific adenine glycosylase
FE795_14660	COG0772	Belongs to the SEDS family
FE795_14665	COG0768	penicillin binding
FE795_14675	COG1792	Involved in formation and maintenance of cell shape
FE795_14680	COG1077	Cell shape determining protein MreB Mrl
FE795_14685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FE795_14690	COG0154	amidase activity
FE795_14695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FE795_14700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FE795_14705	COG0583	DNA-binding transcription factor activity
FE795_14710	COG2259	Doxx family
FE795_14715	COG3384	dioxygenase
FE795_14740	COG3604	Transcriptional regulator
FE795_14775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FE795_14795	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_14800	COG3046	protein related to deoxyribodipyrimidine photolyase
FE795_14810	COG1090	epimerase
FE795_14815	COG0786	glutamate:sodium symporter activity
FE795_14820	COG0142	geranyltranstransferase activity
FE795_14830	COG0494	nUDIX hydrolase
FE795_14840	COG1538	Outer membrane efflux protein
FE795_14850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE795_14855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE795_14860	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FE795_14880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FE795_14885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FE795_14895	COG0477	Major facilitator Superfamily
FE795_14910	COG4206	TonB-dependent receptor
FE795_14915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FE795_14930	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FE795_14935	COG2022	thiamine diphosphate biosynthetic process
FE795_14940	COG0351	phosphomethylpyrimidine kinase
FE795_14945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE795_14950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE795_14960	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FE795_14970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE795_14985	COG2226	methyltransferase
FE795_14990	COG0745	RESPONSE REGULATOR receiver
FE795_15005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FE795_15010	COG1984	allophanate hydrolase subunit 2
FE795_15015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE795_15020	COG1238	metal cluster binding
FE795_15055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FE795_15060	COG4988	ABC transporter
FE795_15070	COG1294	oxidase, subunit
FE795_15075	COG1271	oxidase subunit
FE795_15090	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE795_15105	COG1137	ATPase activity
FE795_15115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE795_15120	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FE795_15125	COG1660	Displays ATPase and GTPase activities
FE795_15135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FE795_15140	COG0792	nuclease activity
FE795_15145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FE795_15160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE795_15170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE795_15175	COG0793	Belongs to the peptidase S41A family
FE795_15180	COG4942	peptidase
FE795_15185	COG0588	phosphoglycerate mutase activity
FE795_15190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FE795_15200	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FE795_15205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FE795_15210	COG3181	Tripartite tricarboxylate transporter family receptor
FE795_15215	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FE795_15220	COG1040	competence protein
FE795_15225	COG2226	methyltransferase
FE795_15235	COG2204	response regulator
FE795_15255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE795_15265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE795_15270	COG3473	Maleate cis-trans isomerase
FE795_15285	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FE795_15300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FE795_15300	COG2755	lipolytic protein G-D-S-L family
FE795_15310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FE795_15320	COG1216	Glycosyl transferase, family 2
FE795_15325	COG1216	Glycosyl transferase, family 2
FE795_15375	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FE795_15390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FE795_15400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FE795_15405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FE795_15410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE795_15425	COG0356	it plays a direct role in the translocation of protons across the membrane
FE795_15435	COG1024	Enoyl-CoA hydratase
FE795_15450	COG0037	tRNA processing
FE795_15455	COG0163	prenyltransferase activity
FE795_15460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE795_15465	COG2890	protein-(glutamine-N5) methyltransferase activity
FE795_15485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE795_15490	COG2264	protein methyltransferase activity
FE795_15505	COG3180	Ammonia monooxygenase
FE795_15525	COG5002	protein histidine kinase activity
FE795_15540	COG0477	Major facilitator Superfamily
FE795_15545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE795_15555	COG0437	4 iron, 4 sulfur cluster binding
FE795_15560	COG2864	formate dehydrogenase
FE795_15570	COG1921	L-seryl-tRNASec selenium transferase activity
FE795_15575	COG3276	selenocysteine insertion sequence binding
FE795_15590	COG4771	TonB-dependent receptor
FE795_15600	COG0709	Synthesizes selenophosphate from selenide and ATP
FE795_15605	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FE795_15610	COG0348	domain, Protein
FE795_15610	COG3901	Regulator of nitric oxide reductase transcription
FE795_15615	COG4263	nitrous-oxide reductase activity
FE795_15630	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FE795_15645	COG0166	Belongs to the GPI family
FE795_15665	COG1215	transferase activity, transferring glycosyl groups
FE795_15675	COG0297	glycogen (starch) synthase activity
FE795_15700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE795_15735	COG0156	8-amino-7-oxononanoate synthase activity
FE795_15740	COG3321	synthase
FE795_15740	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_15740	COG0604	alcohol dehydrogenase
FE795_15745	COG2233	PERMEase
FE795_15755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE795_15760	COG0697	spore germination
FE795_15780	COG2885	chlorophyll binding
FE795_15880	COG0183	Belongs to the thiolase family
FE795_15885	COG1024	Enoyl-CoA hydratase
FE795_15885	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE795_15895	COG2059	Chromate
FE795_15900	COG1127	ABC transporter
FE795_15905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE795_15910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE795_15925	COG1131	(ABC) transporter
FE795_15930	COG0842	Transport permease protein
FE795_15940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE795_15950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE795_15955	COG0131	Imidazoleglycerol-phosphate dehydratase
FE795_15965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FE795_15970	COG0107	imidazoleglycerol-phosphate synthase activity
FE795_15980	COG0140	phosphoribosyl-ATP diphosphatase activity
FE795_15985	COG0537	adenosine 5'-monophosphoramidase activity
FE795_15990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE795_15995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE795_16005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE795_16015	COG1970	mechanosensitive ion channel activity
FE795_16020	COG0723	plastoquinol--plastocyanin reductase activity
FE795_16025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FE795_16030	COG2857	Cytochrome c1
FE795_16035	COG0625	glutathione transferase activity
FE795_16040	COG2969	positive regulation of protein catabolic process
FE795_16045	COG4208	sulfate ABC transporter
FE795_16050	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE795_16055	COG4150	thiosulfate binding
FE795_16075	COG1522	sequence-specific DNA binding
FE795_16080	COG3483	tryptophan 2,3-dioxygenase activity
FE795_16095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FE795_16100	COG0656	L-ascorbic acid biosynthetic process
FE795_16110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FE795_16115	COG3706	GGDEF domain
FE795_16120	COG2226	methyltransferase
FE795_16130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE795_16145	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FE795_16150	COG0583	DNA-binding transcription factor activity
FE795_16155	COG0477	Major facilitator Superfamily
FE795_16160	COG1028	Short-chain dehydrogenase reductase Sdr
FE795_16165	COG1335	isochorismatase
FE795_16185	COG2823	Periplasmic or secreted lipoprotein
FE795_16195	COG3284	Transcriptional regulator
FE795_16210	COG1522	sequence-specific DNA binding
FE795_16220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FE795_16240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE795_16270	COG1612	heme a metabolic process
FE795_16275	COG0109	protoheme IX farnesyltransferase activity
FE795_16315	COG3568	Endonuclease Exonuclease Phosphatase
FE795_16320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE795_16345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE795_16355	COG1228	amidohydrolase
FE795_16365	COG2986	histidine ammonia-lyase
FE795_16370	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FE795_16410	COG0625	glutathione transferase activity
FE795_16435	COG1448	Aminotransferase
FE795_16440	COG2365	Tyrosine phosphatase family
FE795_16445	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FE795_16465	COG2423	ornithine cyclodeaminase activity
FE795_16515	COG3069	C4-dicarboxylate transmembrane transporter activity
FE795_16525	COG1802	Transcriptional regulator
FE795_16540	COG2814	Major facilitator Superfamily
FE795_16550	COG2814	Major facilitator Superfamily
FE795_16560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FE795_16565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FE795_16570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE795_16590	COG5002	protein histidine kinase activity
FE795_16590	COG5001	Diguanylate cyclase
FE795_16595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE795_16600	COG1333	cytochrome c biogenesis protein
FE795_16610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FE795_16615	COG0113	porphobilinogen synthase activity
FE795_16620	COG4232	protein-disulfide reductase activity
FE795_16640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE795_16645	COG0203	ribosomal protein L17
FE795_16650	COG0202	RNA polymerase activity
FE795_16655	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FE795_16660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FE795_16665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FE795_16670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FE795_16680	COG0201	protein transport
FE795_16685	COG0200	Binds to the 23S rRNA
FE795_16690	COG1841	ribosomal large subunit assembly
FE795_16695	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FE795_16700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FE795_16705	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FE795_16710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FE795_16715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE795_16720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FE795_16725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE795_16730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FE795_16770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE795_16785	COG1538	Outer membrane efflux protein
FE795_16805	COG0183	Belongs to the thiolase family
FE795_16810	COG1024	Enoyl-CoA hydratase
FE795_16810	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE795_16830	COG0318	PFAM AMP-dependent synthetase and ligase
FE795_16835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE795_16840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE795_16845	COG1648	precorrin-2 dehydrogenase activity
FE795_16845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE795_16860	COG1116	anion transmembrane transporter activity
FE795_16880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE795_16885	COG0255	Belongs to the universal ribosomal protein uL29 family
FE795_16890	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE795_16895	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FE795_16900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FE795_16905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FE795_16910	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE795_16915	COG0089	rRNA binding
FE795_16920	COG0088	Forms part of the polypeptide exit tunnel
FE795_16925	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FE795_16930	COG4175	Glycine betaine
FE795_16935	COG4176	ABC-type proline glycine betaine transport system permease component
FE795_16940	COG0051	transcription antitermination factor activity, RNA binding
FE795_16945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE795_16950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FE795_16955	COG0049	tRNA binding
FE795_16960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE795_16965	COG0745	RESPONSE REGULATOR receiver
FE795_16975	COG0642	Histidine kinase
FE795_16990	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FE795_17000	COG0085	RNA polymerase activity
FE795_17005	COG0222	ribosome binding
FE795_17010	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE795_17015	COG0081	regulation of translation
FE795_17040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE795_17060	COG1475	DNA binding
FE795_17065	COG1192	Involved in chromosome partitioning
FE795_17070	COG0357	Ribosomal RNA small subunit methyltransferase G
FE795_17075	COG0445	tRNA wobble uridine modification
FE795_17080	COG0436	Aminotransferase
FE795_17085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE795_17090	COG3706	GGDEF domain
FE795_17095	COG0688	phosphatidylethanolamine metabolic process
FE795_17105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE795_17145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE795_17180	COG0753	catalase activity
FE795_17185	COG0706	membrane insertase activity
FE795_17190	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FE795_17195	COG0594	ribonuclease P activity
FE795_17200	COG0230	Belongs to the bacterial ribosomal protein bL34 family