locus-tag	class	description
EGK70_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGK70_000010	COG0592	DNA-directed DNA polymerase activity
EGK70_000045	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_000050	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_000065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGK70_000080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_000100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGK70_000105	COG0583	DNA-binding transcription factor activity
EGK70_000115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EGK70_000125	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGK70_000140	COG0318	PFAM AMP-dependent synthetase and ligase
EGK70_000150	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGK70_000150	COG0596	Alpha beta hydrolase
EGK70_000155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGK70_000170	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_000180	COG0697	spore germination
EGK70_000185	COG0583	DNA-binding transcription factor activity
EGK70_000195	COG3842	ATPase activity
EGK70_000205	COG0436	Aminotransferase
EGK70_000215	COG0523	cobalamin synthesis protein
EGK70_000275	COG1846	Transcriptional regulator
EGK70_000295	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGK70_000300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGK70_000305	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EGK70_000315	COG4638	Rieske (2fe-2S)
EGK70_000375	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_000400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGK70_000415	COG4608	Belongs to the ABC transporter superfamily
EGK70_000420	COG0444	Belongs to the ABC transporter superfamily
EGK70_000425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGK70_000430	COG0601	transmembrane transport
EGK70_000435	COG0747	negative chemotaxis
EGK70_000440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGK70_000445	COG1595	DNA-templated transcription, initiation
EGK70_000450	COG3712	iron ion homeostasis
EGK70_000455	COG4774	siderophore transport
EGK70_000460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGK70_000465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGK70_000500	COG4149	molybdate abc transporter
EGK70_000510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGK70_000515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGK70_000520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_000525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_000540	COG0028	Belongs to the TPP enzyme family
EGK70_000545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_000570	COG0551	DNA topoisomerase type I activity
EGK70_000570	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGK70_000580	COG2922	Belongs to the Smg family
EGK70_000595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGK70_000600	COG0183	Belongs to the thiolase family
EGK70_000605	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EGK70_000610	COG1960	acyl-CoA dehydrogenase activity
EGK70_000630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGK70_000640	COG0018	arginyl-trna synthetase
EGK70_000665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGK70_000680	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGK70_000685	COG4774	siderophore transport
EGK70_000690	COG0066	3-isopropylmalate dehydratase activity
EGK70_000695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGK70_000700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGK70_000705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGK70_000710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_000710	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EGK70_000720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_000730	COG0583	DNA-binding transcription factor activity
EGK70_000750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGK70_000755	COG1280	lysine exporter protein (LysE YggA)
EGK70_000760	COG0513	Belongs to the DEAD box helicase family
EGK70_000770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EGK70_000785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGK70_000840	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGK70_000845	COG1127	ABC transporter
EGK70_000870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGK70_000875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_000885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_000925	COG0583	DNA-binding transcription factor activity
EGK70_000950	COG1254	Belongs to the acylphosphatase family
EGK70_000960	COG2358	TRAP transporter, solute receptor (TAXI family
EGK70_000970	COG0564	pseudouridine synthase activity
EGK70_000975	COG0252	asparaginase activity
EGK70_001000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGK70_001005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGK70_001010	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_001030	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGK70_001055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGK70_001065	COG3712	iron ion homeostasis
EGK70_001085	COG0758	DNA mediated transformation
EGK70_001090	COG0242	peptide deformylase activity
EGK70_001095	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EGK70_001100	COG0697	spore germination
EGK70_001115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_001130	COG4336	lyase activity
EGK70_001135	COG0583	DNA-binding transcription factor activity
EGK70_001140	COG0859	PFAM glycosyl transferase family 9
EGK70_001150	COG1278	Cold shock
EGK70_001155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGK70_001160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EGK70_001165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EGK70_001165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EGK70_001175	COG1686	Belongs to the peptidase S11 family
EGK70_001185	COG2921	Belongs to the UPF0250 family
EGK70_001190	COG0321	lipoyl(octanoyl) transferase activity
EGK70_001195	COG1024	Enoyl-CoA hydratase
EGK70_001200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGK70_001210	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGK70_001255	COG0826	peptidase U32
EGK70_001265	COG3154	lipid carrier protein
EGK70_001290	COG0134	indole-3-glycerol-phosphate synthase activity
EGK70_001295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGK70_001300	COG0512	Glutamine amidotransferase of anthranilate synthase
EGK70_001310	COG0546	phosphoglycolate phosphatase activity
EGK70_001320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGK70_001325	COG2967	ApaG domain
EGK70_001335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGK70_001340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGK70_001350	COG0840	transmembrane signaling receptor activity
EGK70_001360	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_001365	COG3433	isochorismatase activity
EGK70_001365	COG1535	isochorismatase
EGK70_001370	COG1169	isochorismate synthase
EGK70_001385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGK70_001390	COG3433	isochorismatase activity
EGK70_001390	COG1535	isochorismatase
EGK70_001395	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGK70_001410	COG0411	ABC transporter
EGK70_001425	COG0683	leucine binding
EGK70_001440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGK70_001475	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGK70_001480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGK70_001485	COG2819	hydrolase of the alpha beta superfamily
EGK70_001490	COG0513	Belongs to the DEAD box helicase family
EGK70_001495	COG2814	Major facilitator Superfamily
EGK70_001515	COG1253	flavin adenine dinucleotide binding
EGK70_001545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGK70_001550	COG2311	Membrane
EGK70_001575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGK70_001595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGK70_001600	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EGK70_001610	COG0583	DNA-binding transcription factor activity
EGK70_001615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGK70_001620	COG1126	abc transporter atp-binding protein
EGK70_001625	COG0765	amino acid transport
EGK70_001630	COG0765	amino acid transport
EGK70_001635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGK70_001640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGK70_001655	COG3391	amine dehydrogenase activity
EGK70_001665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGK70_001690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EGK70_001695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGK70_001700	COG0210	DNA helicase
EGK70_001715	COG0067	glutamate synthase
EGK70_001715	COG0069	glutamate synthase activity
EGK70_001715	COG0070	glutamate synthase
EGK70_001720	COG1024	Enoyl-CoA hydratase
EGK70_001730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGK70_001735	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGK70_001760	COG2918	glutathione biosynthetic process
EGK70_001770	COG2197	response regulator
EGK70_001775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGK70_001785	COG2223	nitrite transmembrane transporter activity
EGK70_001790	COG2860	membrane
EGK70_001795	COG1346	cytolysis
EGK70_001810	COG0251	oxidation-reduction process
EGK70_001825	COG0745	RESPONSE REGULATOR receiver
EGK70_001840	COG1280	lysine exporter protein (LysE YggA)
EGK70_001845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGK70_001860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EGK70_001875	COG2096	Adenosyltransferase
EGK70_001890	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EGK70_001895	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EGK70_001905	COG0523	cobalamin synthesis protein
EGK70_001910	COG0735	belongs to the Fur family
EGK70_001925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGK70_001930	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGK70_001935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGK70_001945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EGK70_001950	COG1560	Kdo2-lipid A biosynthetic process
EGK70_001960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGK70_001965	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGK70_001970	COG1950	PFAM Membrane protein of
EGK70_002005	COG0275	rRNA processing
EGK70_002010	COG0730	response to heat
EGK70_002015	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EGK70_002020	COG0129	dihydroxy-acid dehydratase activity
EGK70_002030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_002040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_002055	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGK70_002075	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_002085	COG0628	permease
EGK70_002105	COG3311	Transcriptional regulator
EGK70_002120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGK70_002160	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_002165	COG1846	Transcriptional regulator
EGK70_002180	COG0277	FAD linked oxidase domain protein
EGK70_002185	COG1304	FMN binding
EGK70_002190	COG2186	Transcriptional regulator
EGK70_002205	COG2188	Transcriptional regulator
EGK70_002210	COG1522	sequence-specific DNA binding
EGK70_002220	COG1113	amino acid transport
EGK70_002225	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EGK70_002230	COG1349	DNA-binding transcription factor activity
EGK70_002250	COG0395	ABC-type sugar transport system, permease component
EGK70_002265	COG0861	Integral membrane protein TerC family
EGK70_002270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGK70_002280	COG1671	Belongs to the UPF0178 family
EGK70_002290	COG1418	mRNA catabolic process
EGK70_002300	COG4948	Mandelate Racemase Muconate Lactonizing
EGK70_002310	COG0477	Major facilitator Superfamily
EGK70_002325	COG0154	amidase activity
EGK70_002335	COG0583	DNA-binding transcription factor activity
EGK70_002360	COG0326	Molecular chaperone. Has ATPase activity
EGK70_002365	COG4774	siderophore transport
EGK70_002370	COG3128	pkhd-type hydroxylase
EGK70_002395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGK70_002410	COG1652	LysM domain
EGK70_002425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGK70_002435	COG0582	viral genome integration into host DNA
EGK70_002485	COG0629	single-stranded DNA binding
EGK70_002490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGK70_002665	COG2003	Belongs to the UPF0758 family
EGK70_002730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGK70_002745	COG0556	nucleotide-excision repair
EGK70_002775	COG0583	DNA-binding transcription factor activity
EGK70_002805	COG0459	protein refolding
EGK70_002815	COG0583	DNA-binding transcription factor activity
EGK70_002875	COG3173	Aminoglycoside phosphotransferase
EGK70_002940	COG1335	isochorismatase
EGK70_002965	COG0583	DNA-binding transcription factor activity
EGK70_002970	COG0387	Pfam Sodium calcium exchanger
EGK70_002985	COG0477	Major facilitator Superfamily
EGK70_002990	COG0235	Class ii aldolase
EGK70_003000	COG3391	amine dehydrogenase activity
EGK70_003005	COG0590	tRNA wobble adenosine to inosine editing
EGK70_003010	COG3257	ureidoglycine aminohydrolase activity
EGK70_003020	COG0583	DNA-binding transcription factor activity
EGK70_003025	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGK70_003030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGK70_003030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGK70_003040	COG0489	protein tyrosine kinase activity
EGK70_003065	COG2081	HI0933 family
EGK70_003070	COG0509	glycine decarboxylation via glycine cleavage system
EGK70_003080	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EGK70_003085	COG1765	OsmC-like protein
EGK70_003090	COG3278	Belongs to the heme-copper respiratory oxidase family
EGK70_003115	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EGK70_003120	COG0469	pyruvate kinase activity
EGK70_003125	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EGK70_003135	COG2084	Dehydrogenase
EGK70_003140	COG3622	Belongs to the hyi family
EGK70_003145	COG3960	tartronate-semialdehyde synthase activity
EGK70_003150	COG0583	DNA-binding transcription factor activity
EGK70_003160	COG2233	PERMEase
EGK70_003165	COG1942	4-Oxalocrotonate Tautomerase
EGK70_003170	COG0235	Class ii aldolase
EGK70_003180	COG3648	Uricase
EGK70_003180	COG3195	allantoin biosynthetic process
EGK70_003190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGK70_003195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGK70_003210	COG0438	transferase activity, transferring glycosyl groups
EGK70_003220	COG0438	transferase activity, transferring glycosyl groups
EGK70_003230	COG0277	FAD linked oxidase domain protein
EGK70_003240	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGK70_003245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EGK70_003255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGK70_003265	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EGK70_003275	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EGK70_003290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGK70_003295	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGK70_003300	COG0193	aminoacyl-tRNA hydrolase activity
EGK70_003310	COG0012	GTP binding
EGK70_003335	COG1024	Enoyl-CoA hydratase
EGK70_003340	COG0367	asparagine synthase
EGK70_003365	COG0488	(ABC) transporter
EGK70_003375	COG0288	reversible hydration of carbon dioxide
EGK70_003380	COG0583	DNA-binding transcription factor activity
EGK70_003410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EGK70_003420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGK70_003425	COG3088	subunit of a heme lyase
EGK70_003430	COG4235	cytochrome complex assembly
EGK70_003435	COG0785	Cytochrome C biogenesis protein
EGK70_003445	COG2169	Transcriptional regulator
EGK70_003445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGK70_003465	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGK70_003475	COG0411	ABC transporter
EGK70_003485	COG1858	cytochrome C peroxidase
EGK70_003490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGK70_003495	COG1959	2 iron, 2 sulfur cluster binding
EGK70_003500	COG2346	COG2346, Truncated hemoglobins
EGK70_003505	COG0463	Glycosyl transferase, family 2
EGK70_003545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGK70_003550	COG3383	formate dehydrogenase (NAD+) activity
EGK70_003565	COG1910	domain protein
EGK70_003570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGK70_003590	COG0303	'Molybdopterin
EGK70_003595	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGK70_003600	COG0314	molybdopterin synthase activity
EGK70_003610	COG0315	cyclic pyranopterin monophosphate synthase activity
EGK70_003640	COG0678	peroxiredoxin activity
EGK70_003650	COG0697	spore germination
EGK70_003655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EGK70_003675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGK70_003720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGK70_003725	COG4535	Mg2 and Co2 transporter CorC
EGK70_003730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGK70_003735	COG1702	phosphate starvation-inducible protein PhoH
EGK70_003740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGK70_003760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGK70_003765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGK70_003770	COG1862	Preprotein translocase
EGK70_003775	COG0343	queuine tRNA-ribosyltransferase activity
EGK70_003780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGK70_003785	COG2027	D-alanyl-D-alanine carboxypeptidase
EGK70_003800	COG4575	ribosome binding
EGK70_003815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EGK70_003825	COG0436	Aminotransferase
EGK70_003835	COG0280	phosphate acetyltransferase
EGK70_003835	COG0281	malic enzyme
EGK70_003845	COG2732	(Barnase) inhibitor
EGK70_003850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGK70_003855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGK70_003860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGK70_003865	COG0126	phosphoglycerate kinase activity
EGK70_003890	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGK70_003900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EGK70_003905	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGK70_003910	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGK70_003915	COG0009	L-threonylcarbamoyladenylate synthase
EGK70_003920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGK70_003925	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_003925	COG2030	dehydratase
EGK70_003930	COG1960	acyl-CoA dehydrogenase activity
EGK70_003940	COG0405	Gamma-glutamyltransferase
EGK70_003950	COG0579	oxidoreductase
EGK70_003955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGK70_003960	COG0259	pyridoxamine-phosphate oxidase activity
EGK70_003970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGK70_003985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGK70_003990	COG1215	transferase activity, transferring glycosyl groups
EGK70_004000	COG0488	(ABC) transporter
EGK70_004020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGK70_004025	COG2894	cell division
EGK70_004035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGK70_004045	COG1294	oxidase, subunit
EGK70_004050	COG0038	chloride channel
EGK70_004060	COG0514	ATP-dependent DNA helicase (RecQ)
EGK70_004065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGK70_004070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGK70_004075	COG0633	Ferredoxin
EGK70_004080	COG0488	(ABC) transporter
EGK70_004090	COG2001	Belongs to the MraZ family
EGK70_004095	COG0275	rRNA processing
EGK70_004100	COG3116	cell division
EGK70_004110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGK70_004115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGK70_004120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGK70_004130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EGK70_004135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGK70_004140	COG1181	Belongs to the D-alanine--D-alanine ligase family
EGK70_004145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGK70_004160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EGK70_004170	COG0739	heme binding
EGK70_004170	COG0741	lytic transglycosylase activity
EGK70_004170	COG1196	nuclear chromosome segregation
EGK70_004175	COG0653	protein targeting
EGK70_004185	COG2239	Acts as a magnesium transporter
EGK70_004195	COG1473	amidohydrolase
EGK70_004200	COG0318	PFAM AMP-dependent synthetase and ligase
EGK70_004210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGK70_004210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGK70_004225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGK70_004230	COG2011	ABC-type metal ion transport system permease component
EGK70_004240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGK70_004245	COG0765	amino acid transport
EGK70_004250	COG1126	abc transporter atp-binding protein
EGK70_004275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGK70_004280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGK70_004285	COG0700	Nucleoside recognition
EGK70_004300	COG0204	Acyl-transferase
EGK70_004305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGK70_004310	COG0751	glycine-tRNA ligase activity
EGK70_004315	COG0752	glycyl-tRNA synthetase alpha subunit
EGK70_004330	COG1309	transcriptional regulator
EGK70_004340	COG2814	Major facilitator Superfamily
EGK70_004355	COG0617	tRNA 3'-terminal CCA addition
EGK70_004365	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGK70_004370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGK70_004375	COG1953	Uracil, thiamine, allantoin
EGK70_004380	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EGK70_004385	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGK70_004390	COG0586	Pfam SNARE associated Golgi protein
EGK70_004395	COG1477	protein flavinylation
EGK70_004415	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGK70_004420	COG0802	atpase or kinase
EGK70_004430	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_004435	COG0280	phosphate acetyltransferase
EGK70_004435	COG0281	malic enzyme
EGK70_004440	COG0583	DNA-binding transcription factor activity
EGK70_004445	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_004450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGK70_004470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_004485	COG1733	regulation of RNA biosynthetic process
EGK70_004490	COG2910	NAD(P)H-binding
EGK70_004500	COG2223	nitrite transmembrane transporter activity
EGK70_004505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGK70_004510	COG4974	Belongs to the 'phage' integrase family
EGK70_004515	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGK70_004520	COG4149	molybdate abc transporter
EGK70_004525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EGK70_004540	COG1074	ATP-dependent DNA helicase activity
EGK70_004575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGK70_004580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGK70_004585	COG0505	Belongs to the CarA family
EGK70_004590	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGK70_004610	COG2233	PERMEase
EGK70_004615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGK70_004620	COG1534	Rna-binding protein
EGK70_004625	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EGK70_004630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGK70_004640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGK70_004650	COG0248	Ppx GppA phosphatase
EGK70_004655	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGK70_004675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGK70_004680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGK70_004735	COG1368	sulfuric ester hydrolase activity
EGK70_004765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGK70_004770	COG3327	negative regulation of DNA-templated transcription, initiation
EGK70_004775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGK70_004790	COG0009	L-threonylcarbamoyladenylate synthase
EGK70_004795	COG1994	Peptidase M50
EGK70_004800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGK70_004805	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGK70_004820	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGK70_004830	COG0156	8-amino-7-oxononanoate synthase activity
EGK70_004835	COG2124	cytochrome p450
EGK70_004840	COG3135	benzoate transporter
EGK70_004845	COG2850	peptidyl-arginine hydroxylation
EGK70_004850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EGK70_004855	COG3391	amine dehydrogenase activity
EGK70_004870	COG0577	efflux transmembrane transporter activity
EGK70_004870	COG1136	(ABC) transporter
EGK70_004875	COG1538	Outer membrane efflux protein
EGK70_004880	COG0363	glucosamine-6-phosphate deaminase activity
EGK70_004885	COG1132	(ABC) transporter
EGK70_004895	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_004905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGK70_004915	COG0668	transmembrane transport
EGK70_004960	COG0154	amidase activity
EGK70_004965	COG2031	fatty acid transporter
EGK70_004975	COG2814	Major facilitator Superfamily
EGK70_004985	COG0667	Aldo Keto reductase
EGK70_005010	COG0483	inositol monophosphate 1-phosphatase activity
EGK70_005015	COG1253	flavin adenine dinucleotide binding
EGK70_005020	COG1968	undecaprenyl-diphosphatase activity
EGK70_005040	COG0215	cysteine-tRNA ligase activity
EGK70_005050	COG0825	malonyl-CoA metabolic process
EGK70_005055	COG0037	tRNA processing
EGK70_005080	COG0330	HflC and HflK could
EGK70_005095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGK70_005120	COG4208	sulfate ABC transporter
EGK70_005125	COG3842	ATPase activity
EGK70_005135	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGK70_005165	COG1304	FMN binding
EGK70_005170	COG0435	Glutathione S-transferase
EGK70_005175	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGK70_005190	COG2094	Belongs to the DNA glycosylase MPG family
EGK70_005195	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EGK70_005200	COG2363	Small membrane protein
EGK70_005205	COG0598	Magnesium transport protein CorA
EGK70_005210	COG1960	acyl-CoA dehydrogenase activity
EGK70_005220	COG0747	negative chemotaxis
EGK70_005230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGK70_005235	COG4172	Belongs to the ABC transporter superfamily
EGK70_005245	COG3284	Transcriptional regulator
EGK70_005250	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_005255	COG1454	alcohol dehydrogenase
EGK70_005260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGK70_005285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EGK70_005320	COG3829	transcription factor binding
EGK70_005325	COG0477	Major facilitator Superfamily
EGK70_005335	COG0039	L-malate dehydrogenase activity
EGK70_005340	COG2188	Transcriptional regulator
EGK70_005345	COG2009	succinate dehydrogenase
EGK70_005355	COG1053	succinate dehydrogenase
EGK70_005360	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGK70_005365	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGK70_005370	COG0372	Belongs to the citrate synthase family
EGK70_005375	COG2186	Transcriptional regulator
EGK70_005380	COG1620	l-lactate permease
EGK70_005385	COG0281	malic enzyme
EGK70_005385	COG0280	phosphate acetyltransferase
EGK70_005390	COG0567	Dehydrogenase, E1 component
EGK70_005395	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGK70_005400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGK70_005405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGK70_005425	COG2183	response to ionizing radiation
EGK70_005430	COG1199	ATP-dependent helicase activity
EGK70_005435	COG0659	secondary active sulfate transmembrane transporter activity
EGK70_005445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGK70_005445	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EGK70_005450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGK70_005475	COG0564	pseudouridine synthase activity
EGK70_005485	COG3243	poly(R)-hydroxyalkanoic acid synthase
EGK70_005490	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_005495	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EGK70_005535	COG3328	transposase activity
EGK70_005570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGK70_005575	COG1187	pseudouridine synthase activity
EGK70_005580	COG0779	Required for maturation of 30S ribosomal subunits
EGK70_005585	COG0195	Participates in both transcription termination and antitermination
EGK70_005585	COG2251	uridine kinase activity
EGK70_005590	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EGK70_005595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGK70_005600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGK70_005605	COG1217	gtp-binding protein TYPA
EGK70_005610	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGK70_005620	COG4160	amino acid transport
EGK70_005625	COG4215	(ABC) transporter
EGK70_005635	COG1611	Belongs to the LOG family
EGK70_005645	COG1283	sodium-dependent phosphate transmembrane transporter activity
EGK70_005650	COG0501	Belongs to the peptidase M48B family
EGK70_005665	COG1722	exodeoxyribonuclease VII activity
EGK70_005670	COG0142	geranyltranstransferase activity
EGK70_005675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGK70_005680	COG1469	GTP cyclohydrolase I activity
EGK70_005685	COG0360	Binds together with S18 to 16S ribosomal RNA
EGK70_005690	COG2965	DNA replication, synthesis of RNA primer
EGK70_005695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGK70_005700	COG0359	binds to the 23S rRNA
EGK70_005705	COG0305	Participates in initiation and elongation during chromosome replication
EGK70_005715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EGK70_005720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EGK70_005725	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGK70_005735	COG0436	Aminotransferase
EGK70_005755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGK70_005760	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EGK70_005765	COG1562	ergosterol biosynthetic process
EGK70_005770	COG1562	ergosterol biosynthetic process
EGK70_005775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGK70_005780	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_005805	COG3842	ATPase activity
EGK70_005810	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGK70_005815	COG1177	transmembrane transport
EGK70_005820	COG1393	Belongs to the ArsC family
EGK70_005825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGK70_005830	COG0704	Plays a role in the regulation of phosphate uptake
EGK70_005835	COG4251	negative regulation of phosphorylation
EGK70_005835	COG5001	Diguanylate cyclase
EGK70_005835	COG2203	Gaf domain
EGK70_005835	COG3706	GGDEF domain
EGK70_005840	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EGK70_005845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGK70_005845	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EGK70_005850	COG1643	Atp-dependent helicase
EGK70_005860	COG0438	transferase activity, transferring glycosyl groups
EGK70_005865	COG0726	polysaccharide deacetylase
EGK70_005880	COG0297	glycogen (starch) synthase activity
EGK70_005905	COG1132	(ABC) transporter
EGK70_005950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGK70_005970	COG2186	Transcriptional regulator
EGK70_005975	COG0277	FAD linked oxidase domain protein
EGK70_005980	COG0277	FAD linked oxidase domain protein
EGK70_005985	COG0247	lactate metabolic process
EGK70_006015	COG2159	amidohydrolase
EGK70_006030	COG0583	DNA-binding transcription factor activity
EGK70_006035	COG0477	Major facilitator Superfamily
EGK70_006085	COG0628	permease
EGK70_006090	COG1283	sodium-dependent phosphate transmembrane transporter activity
EGK70_006105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGK70_006115	COG0697	spore germination
EGK70_006135	COG3094	Invasion gene expression up-regulator, SirB
EGK70_006145	COG0640	Transcriptional regulator
EGK70_006170	COG0659	secondary active sulfate transmembrane transporter activity
EGK70_006175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGK70_006185	COG2314	TM2 domain
EGK70_006190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGK70_006195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGK70_006200	COG0791	NLP P60 protein
EGK70_006220	COG1360	Flagellar Motor Protein
EGK70_006230	COG0835	chemotaxis
EGK70_006235	COG0840	transmembrane signaling receptor activity
EGK70_006240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGK70_006250	COG0745	RESPONSE REGULATOR receiver
EGK70_006255	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGK70_006260	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGK70_006265	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGK70_006275	COG3550	peptidyl-serine autophosphorylation
EGK70_006300	COG1815	bacterial-type flagellum-dependent cell motility
EGK70_006305	COG1558	bacterial-type flagellum-dependent cell motility
EGK70_006310	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGK70_006350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EGK70_006365	COG0840	transmembrane signaling receptor activity
EGK70_006385	COG1987	bacterial-type flagellum assembly
EGK70_006400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGK70_006425	COG1157	protein secretion by the type III secretion system
EGK70_006440	COG1766	The M ring may be actively involved in energy transduction
EGK70_006445	COG1677	Flagellar hook-basal body complex protein FliE
EGK70_006450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGK70_006475	COG1334	flagellar protein FlaG
EGK70_006480	COG1191	sigma factor activity
EGK70_006550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGK70_006570	COG2733	membrane
EGK70_006575	COG0840	transmembrane signaling receptor activity
EGK70_006580	COG0840	transmembrane signaling receptor activity
EGK70_006610	COG2610	gluconate transmembrane transporter activity
EGK70_006625	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGK70_006630	COG3657	addiction module killer protein
EGK70_006635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGK70_006650	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_006660	COG2824	Alkylphosphonate utilization operon protein PhnA
EGK70_006675	COG4771	TonB-dependent receptor
EGK70_006680	COG1858	cytochrome C peroxidase
EGK70_006685	COG1454	alcohol dehydrogenase
EGK70_006705	COG0668	transmembrane transport
EGK70_006710	COG1113	amino acid transport
EGK70_006715	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGK70_006755	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGK70_006780	COG1278	Cold shock
EGK70_006785	COG0642	Histidine kinase
EGK70_006795	COG3278	Belongs to the heme-copper respiratory oxidase family
EGK70_006805	COG2863	cytochrome
EGK70_006810	COG3258	Cytochrome c
EGK70_006815	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGK70_006820	COG4774	siderophore transport
EGK70_006855	COG0025	NhaP-type Na H and K H
EGK70_006870	COG1289	transmembrane transporter activity
EGK70_006875	COG2252	PERMEase
EGK70_006895	COG1999	signal sequence binding
EGK70_006910	COG0069	glutamate synthase activity
EGK70_006920	COG1846	Transcriptional regulator
EGK70_006925	COG1058	Belongs to the CinA family
EGK70_006925	COG1546	Belongs to the CinA family
EGK70_006930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGK70_006970	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_006980	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_006995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGK70_007005	COG3264	Mechanosensitive ion channel
EGK70_007005	COG1511	domain protein
EGK70_007010	COG3264	Mechanosensitive ion channel
EGK70_007010	COG1511	domain protein
EGK70_007015	COG0477	Major facilitator Superfamily
EGK70_007030	COG1396	sequence-specific DNA binding
EGK70_007035	COG3437	response regulator, receiver
EGK70_007040	COG0784	Response regulator, receiver
EGK70_007040	COG2205	protein histidine kinase activity
EGK70_007040	COG2198	Histidine kinase
EGK70_007045	COG2239	Acts as a magnesium transporter
EGK70_007055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EGK70_007060	COG1490	D-aminoacyl-tRNA deacylase activity
EGK70_007075	COG0456	acetyltransferase
EGK70_007080	COG3012	SEC-C Motif Domain Protein
EGK70_007085	COG0501	Belongs to the peptidase M48B family
EGK70_007200	COG1396	sequence-specific DNA binding
EGK70_007280	COG5410	chromosome segregation
EGK70_007410	COG2135	peptidase activity
EGK70_007530	COG3772	lysozyme
EGK70_007580	COG3706	GGDEF domain
EGK70_007595	COG1522	sequence-specific DNA binding
EGK70_007600	COG0626	cystathionine gamma-synthase activity
EGK70_007610	COG0494	nUDIX hydrolase
EGK70_007615	COG2832	Protein of unknown function (DUF454)
EGK70_007625	COG0137	argininosuccinate synthase activity
EGK70_007630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGK70_007655	COG1609	Transcriptional regulator
EGK70_007660	COG0519	Catalyzes the synthesis of GMP from XMP
EGK70_007660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGK70_007670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGK70_007680	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EGK70_007685	COG2205	protein histidine kinase activity
EGK70_007690	COG0745	RESPONSE REGULATOR receiver
EGK70_007695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EGK70_007705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGK70_007710	COG0268	Binds directly to 16S ribosomal RNA
EGK70_007715	COG0728	peptidoglycan biosynthetic process
EGK70_007725	COG0563	adenylate kinase activity
EGK70_007730	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EGK70_007735	COG2835	tetraacyldisaccharide 4'-kinase activity
EGK70_007740	COG1663	tetraacyldisaccharide 4'-kinase activity
EGK70_007745	COG0848	biopolymer transport protein
EGK70_007750	COG0811	peptide transport
EGK70_007755	COG1570	exodeoxyribonuclease VII activity
EGK70_007760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGK70_007770	COG0183	Belongs to the thiolase family
EGK70_007780	COG1278	Cold shock
EGK70_007785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EGK70_007790	COG0542	response to heat
EGK70_007795	COG2995	paraquat-inducible protein a
EGK70_007800	COG3008	intermembrane lipid transfer
EGK70_007800	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGK70_007820	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGK70_007850	COG0300	oxidoreductase activity
EGK70_007880	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EGK70_007885	COG0756	dUTP diphosphatase activity
EGK70_007895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGK70_007900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGK70_007905	COG0196	riboflavin kinase activity
EGK70_007910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGK70_007915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGK70_007915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGK70_007925	COG0210	DNA helicase
EGK70_007950	COG0488	(ABC) transporter
EGK70_007955	COG2890	protein-(glutamine-N5) methyltransferase activity
EGK70_007960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGK70_007965	COG2171	N-acyltransferase activity
EGK70_007975	COG2207	Transcriptional regulator
EGK70_007985	COG0471	metal ion transport
EGK70_007985	COG3273	potassium ion transport
EGK70_008045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGK70_008050	COG0544	peptidyl-prolyl cis-trans isomerase activity
EGK70_008055	COG0740	serine-type endopeptidase activity
EGK70_008065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGK70_008075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGK70_008085	COG0556	nucleotide-excision repair
EGK70_008090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGK70_008100	COG1104	cysteine desulfurase activity
EGK70_008110	COG0316	Belongs to the HesB IscA family
EGK70_008175	COG0798	PFAM Bile acid sodium symporter
EGK70_008205	COG4691	Plasmid stability protein
EGK70_008230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGK70_008230	COG0519	Catalyzes the synthesis of GMP from XMP
EGK70_008245	COG0047	phosphoribosylformylglycinamidine synthase activity
EGK70_008245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGK70_008255	COG0613	PHP domain protein
EGK70_008270	COG0084	hydrolase, TatD family'
EGK70_008275	COG1136	(ABC) transporter
EGK70_008290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGK70_008300	COG0385	Bile acid
EGK70_008305	COG0697	spore germination
EGK70_008310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGK70_008315	COG0840	transmembrane signaling receptor activity
EGK70_008325	COG4221	oxidoreductase activity
EGK70_008330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EGK70_008385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGK70_008405	COG0583	DNA-binding transcription factor activity
EGK70_008420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EGK70_008430	COG1960	acyl-CoA dehydrogenase activity
EGK70_008440	COG2378	regulation of single-species biofilm formation
EGK70_008445	COG0523	cobalamin synthesis protein
EGK70_008450	COG1469	GTP cyclohydrolase I activity
EGK70_008455	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGK70_008465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EGK70_008470	COG0735	belongs to the Fur family
EGK70_008475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGK70_008485	COG0494	nUDIX hydrolase
EGK70_008490	COG1942	4-Oxalocrotonate Tautomerase
EGK70_008505	COG2070	2-Nitropropane dioxygenase
EGK70_008510	COG0583	DNA-binding transcription factor activity
EGK70_008545	COG0494	nUDIX hydrolase
EGK70_008550	COG0625	glutathione transferase activity
EGK70_008555	COG0740	serine-type endopeptidase activity
EGK70_008605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGK70_008615	COG1960	acyl-CoA dehydrogenase activity
EGK70_008635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGK70_008640	COG0640	Transcriptional regulator
EGK70_008665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGK70_008680	COG3485	protocatechuate 3,4-dioxygenase
EGK70_008690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGK70_008695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGK70_008705	COG3135	benzoate transporter
EGK70_008710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGK70_008715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EGK70_008725	COG4555	ABC transporter
EGK70_008735	COG2197	response regulator
EGK70_008740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGK70_008765	COG1846	Transcriptional regulator
EGK70_008770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGK70_008775	COG2271	Major facilitator Superfamily
EGK70_008785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGK70_008795	COG0697	spore germination
EGK70_008820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGK70_008825	COG0667	Aldo Keto reductase
EGK70_008840	COG0456	acetyltransferase
EGK70_008850	COG1272	protein, Hemolysin III
EGK70_008855	COG3422	double-strand break repair
EGK70_008865	COG0477	Major facilitator Superfamily
EGK70_008870	COG0154	amidase activity
EGK70_008895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGK70_008900	COG0765	amino acid transport
EGK70_008905	COG0765	amino acid transport
EGK70_008910	COG1126	abc transporter atp-binding protein
EGK70_008960	COG2871	sodium ion transport
EGK70_008975	COG3039	Transposase
EGK70_008980	COG3039	Transposase
EGK70_009010	COG2814	Major facilitator Superfamily
EGK70_009020	COG1280	lysine exporter protein (LysE YggA)
EGK70_009040	COG0402	S-adenosylhomocysteine deaminase activity
EGK70_009060	COG0330	HflC and HflK could
EGK70_009065	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGK70_009070	COG2226	methyltransferase
EGK70_009080	COG3042	response to heat
EGK70_009090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGK70_009100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EGK70_009105	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EGK70_009120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGK70_009125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGK70_009155	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EGK70_009160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EGK70_009165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EGK70_009170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGK70_009170	COG0072	phenylalanine-tRNA ligase activity
EGK70_009185	COG2833	Protein of unknown function (DUF455)
EGK70_009195	COG5265	(ABC) transporter
EGK70_009200	COG1959	2 iron, 2 sulfur cluster binding
EGK70_009205	COG0719	Fe-S assembly protein
EGK70_009210	COG0396	ATPase activity
EGK70_009215	COG0719	Fe-S assembly protein
EGK70_009225	COG0822	iron-sulfur transferase activity
EGK70_009230	COG2151	metal-sulfur cluster biosynthetic enzyme
EGK70_009265	COG1215	transferase activity, transferring glycosyl groups
EGK70_009270	COG0726	polysaccharide deacetylase
EGK70_009270	COG1649	PFAM Uncharacterised BCR, COG1649
EGK70_009275	COG0457	Tetratricopeptide repeat
EGK70_009285	COG1278	Cold shock
EGK70_009340	COG0747	negative chemotaxis
EGK70_009345	COG0601	transmembrane transport
EGK70_009350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGK70_009355	COG4172	Belongs to the ABC transporter superfamily
EGK70_009365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGK70_009420	COG3949	Membrane
EGK70_009430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGK70_009445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGK70_009450	COG0569	domain protein
EGK70_009455	COG1902	pentaerythritol trinitrate reductase activity
EGK70_009465	COG1610	YqeY-like protein
EGK70_009470	COG0587	DNA-directed DNA polymerase activity
EGK70_009500	COG2988	succinylglutamate desuccinylase activity
EGK70_009505	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_009510	COG0583	DNA-binding transcription factor activity
EGK70_009515	COG1686	Belongs to the peptidase S11 family
EGK70_009540	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_009545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGK70_009550	COG4221	oxidoreductase activity
EGK70_009555	COG0307	riboflavin synthase, alpha
EGK70_009570	COG1301	dicarboxylic acid transport
EGK70_009575	COG4191	Histidine kinase
EGK70_009585	COG0583	DNA-binding transcription factor activity
EGK70_009590	COG1053	succinate dehydrogenase
EGK70_009640	COG2233	PERMEase
EGK70_009645	COG0071	Belongs to the small heat shock protein (HSP20) family
EGK70_009650	COG1473	amidohydrolase
EGK70_009660	COG2814	Major facilitator Superfamily
EGK70_009685	COG1846	Transcriptional regulator
EGK70_009690	COG2816	NAD+ diphosphatase activity
EGK70_009695	COG1561	YicC-like family, N-terminal region
EGK70_009710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EGK70_009715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGK70_009720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGK70_009725	COG0174	glutamine synthetase
EGK70_009730	COG2153	protein acetylation
EGK70_009750	COG3842	ATPase activity
EGK70_009755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGK70_009760	COG1840	ABC-type Fe3 transport system, periplasmic component
EGK70_009775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGK70_009785	COG0783	Belongs to the Dps family
EGK70_009795	COG3842	ATPase activity
EGK70_009800	COG0395	ABC-type sugar transport system, permease component
EGK70_009805	COG1175	transmembrane transport
EGK70_009810	COG1653	transport
EGK70_009825	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGK70_009850	COG0625	glutathione transferase activity
EGK70_009860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGK70_009865	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_009870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGK70_009875	COG0114	fumarate hydratase activity
EGK70_009880	COG2133	pyrroloquinoline quinone binding
EGK70_009885	COG2226	methyltransferase
EGK70_009890	COG0589	response to stress
EGK70_009900	COG2807	transmembrane transport
EGK70_009910	COG0583	DNA-binding transcription factor activity
EGK70_009930	COG4974	Belongs to the 'phage' integrase family
EGK70_009940	COG2132	Multicopper oxidase
EGK70_009945	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EGK70_010080	COG1061	Type III restriction enzyme res subunit
EGK70_010115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGK70_010175	COG2003	Belongs to the UPF0758 family
EGK70_010220	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EGK70_010270	COG2894	cell division
EGK70_010365	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_010390	COG3038	cytochrome b561
EGK70_010400	COG2353	YceI-like domain
EGK70_010405	COG1393	Belongs to the ArsC family
EGK70_010410	COG0625	glutathione transferase activity
EGK70_010430	COG0084	hydrolase, TatD family'
EGK70_010435	COG0470	DNA polymerase III
EGK70_010445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGK70_010465	COG1960	acyl-CoA dehydrogenase activity
EGK70_010470	COG2914	Belongs to the UPF0125 (RnfH) family
EGK70_010475	COG2867	negative regulation of translational initiation
EGK70_010480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EGK70_010485	COG1252	NADH dehydrogenase
EGK70_010510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGK70_010515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGK70_010520	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGK70_010530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGK70_010535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGK70_010545	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGK70_010555	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EGK70_010560	COG0575	Belongs to the CDS family
EGK70_010565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGK70_010570	COG0233	cytoplasmic translational termination
EGK70_010575	COG0528	UMP kinase activity
EGK70_010580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EGK70_010585	COG0052	Belongs to the universal ribosomal protein uS2 family
EGK70_010590	COG0024	Methionine aminopeptidase
EGK70_010595	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EGK70_010620	COG1286	toxin biosynthetic process
EGK70_010630	COG0285	dihydrofolate synthase activity
EGK70_010635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGK70_010640	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGK70_010645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGK70_010660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGK70_010670	COG1999	signal sequence binding
EGK70_010690	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGK70_010700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGK70_010705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGK70_010710	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EGK70_010730	COG0183	Belongs to the thiolase family
EGK70_010735	COG0183	Belongs to the thiolase family
EGK70_010780	COG0194	GDP metabolic process
EGK70_010785	COG1758	RNA polymerase activity
EGK70_010790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGK70_010800	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGK70_010805	COG0739	heme binding
EGK70_010810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGK70_010815	COG0584	glycerophosphoryl diester phosphodiesterase
EGK70_010820	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGK70_010825	COG1187	pseudouridine synthase activity
EGK70_010830	COG3161	chorismate lyase activity
EGK70_010835	COG2814	Major facilitator Superfamily
EGK70_010840	COG0656	L-ascorbic acid biosynthetic process
EGK70_010850	COG0668	transmembrane transport
EGK70_010855	COG0165	Argininosuccinate lyase
EGK70_010875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGK70_010885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGK70_010895	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGK70_010900	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EGK70_010905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EGK70_010910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EGK70_010915	COG2252	PERMEase
EGK70_010920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGK70_010940	COG0488	(ABC) transporter
EGK70_010945	COG1619	proteins homologs of microcin C7 resistance protein MccF
EGK70_010950	COG0590	tRNA wobble adenosine to inosine editing
EGK70_010955	COG1131	(ABC) transporter
EGK70_010960	COG0842	Transport permease protein
EGK70_010970	COG1666	GTP binding
EGK70_010975	COG0318	PFAM AMP-dependent synthetase and ligase
EGK70_010980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGK70_010985	COG0519	Catalyzes the synthesis of GMP from XMP
EGK70_010985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGK70_010990	COG2207	Transcriptional regulator
EGK70_011005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGK70_011010	COG0135	phosphoribosylanthranilate isomerase activity
EGK70_011015	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_011025	COG0101	tRNA pseudouridine synthase activity
EGK70_011035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGK70_011040	COG0473	3-isopropylmalate dehydrogenase activity
EGK70_011055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGK70_011065	COG4566	intracellular signal transduction
EGK70_011080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EGK70_011085	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGK70_011095	COG1295	ribonuclease BN
EGK70_011105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGK70_011135	COG4964	Belongs to the GSP D family
EGK70_011175	COG3712	iron ion homeostasis
EGK70_011180	COG1595	DNA-templated transcription, initiation
EGK70_011190	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGK70_011200	COG2959	enzyme of heme biosynthesis
EGK70_011210	COG0181	hydroxymethylbilane synthase activity
EGK70_011215	COG0861	Integral membrane protein TerC family
EGK70_011220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGK70_011225	COG0045	succinate-CoA ligase (ADP-forming) activity
EGK70_011240	COG0583	DNA-binding transcription factor activity
EGK70_011245	COG2137	regulation of response to DNA damage stimulus
EGK70_011265	COG0477	Major facilitator Superfamily
EGK70_011280	COG0318	PFAM AMP-dependent synthetase and ligase
EGK70_011285	COG1024	Enoyl-CoA hydratase
EGK70_011290	COG3162	membrane
EGK70_011305	COG0540	Belongs to the ATCase OTCase family
EGK70_011320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGK70_011335	COG2070	2-Nitropropane dioxygenase
EGK70_011340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGK70_011345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGK70_011345	COG2111	Na H antiporter
EGK70_011350	COG1006	Multisubunit Na H antiporter MnhC subunit
EGK70_011355	COG0651	ATP synthesis coupled electron transport
EGK70_011365	COG2212	antiporter activity
EGK70_011380	COG3158	transport of potassium into the cell
EGK70_011385	COG0642	Histidine kinase
EGK70_011410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGK70_011415	COG4208	sulfate ABC transporter
EGK70_011420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGK70_011425	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGK70_011440	COG1278	Cold shock
EGK70_011465	COG1648	precorrin-2 dehydrogenase activity
EGK70_011465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGK70_011470	COG2010	Cytochrome c
EGK70_011480	COG1522	sequence-specific DNA binding
EGK70_011495	COG0535	radical SAM domain protein
EGK70_011505	COG1648	precorrin-2 dehydrogenase activity
EGK70_011505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGK70_011515	COG2010	Cytochrome c
EGK70_011520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGK70_011530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGK70_011535	COG0557	exoribonuclease II activity
EGK70_011565	COG2375	cellular response to nickel ion
EGK70_011595	COG0583	DNA-binding transcription factor activity
EGK70_011600	COG3842	ATPase activity
EGK70_011610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGK70_011615	COG1840	ABC-type Fe3 transport system, periplasmic component
EGK70_011640	COG3530	Putative quorum-sensing-regulated virulence factor
EGK70_011645	COG0625	glutathione transferase activity
EGK70_011655	COG1741	Belongs to the pirin family
EGK70_011665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGK70_011670	COG2814	Major facilitator Superfamily
EGK70_011675	COG2807	transmembrane transport
EGK70_011680	COG2207	Transcriptional regulator
EGK70_011685	COG3135	benzoate transporter
EGK70_011710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGK70_011720	COG0402	S-adenosylhomocysteine deaminase activity
EGK70_011730	COG0745	RESPONSE REGULATOR receiver
EGK70_011735	COG2205	protein histidine kinase activity
EGK70_011750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EGK70_011755	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EGK70_011760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGK70_011765	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EGK70_011770	COG0330	HflC and HflK could
EGK70_011775	COG0330	HflC and HflK could
EGK70_011780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGK70_011785	COG1923	regulation of RNA biosynthetic process
EGK70_011795	COG1160	GTP binding
EGK70_011800	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGK70_011805	COG2976	Protein conserved in bacteria
EGK70_011825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EGK70_011830	COG0105	UTP biosynthetic process
EGK70_011845	COG0336	Belongs to the RNA methyltransferase TrmD family
EGK70_011855	COG0228	four-way junction DNA binding
EGK70_011860	COG0425	Belongs to the sulfur carrier protein TusA family
EGK70_011865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EGK70_011880	COG2351	hydroxyisourate hydrolase activity
EGK70_011915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGK70_011940	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGK70_011945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGK70_011970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGK70_011975	COG0601	transmembrane transport
EGK70_012005	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EGK70_012010	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGK70_012015	COG0542	response to heat
EGK70_012020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGK70_012035	COG0348	domain, Protein
EGK70_012055	COG3278	Belongs to the heme-copper respiratory oxidase family
EGK70_012065	COG2217	Heavy metal translocating P-type atpase
EGK70_012070	COG2224	Isocitrate lyase
EGK70_012075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGK70_012075	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EGK70_012095	COG1472	Belongs to the glycosyl hydrolase 3 family
EGK70_012100	COG0736	holo-[acyl-carrier-protein] synthase activity
EGK70_012110	COG2050	protein possibly involved in aromatic compounds catabolism
EGK70_012115	COG1024	Enoyl-CoA hydratase
EGK70_012120	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_012125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGK70_012130	COG2151	metal-sulfur cluster biosynthetic enzyme
EGK70_012135	COG3396	Phenylacetate-CoA oxygenase
EGK70_012140	COG3460	Phenylacetate-CoA oxygenase
EGK70_012145	COG3396	Phenylacetate-CoA oxygenase
EGK70_012150	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGK70_012155	COG0501	Belongs to the peptidase M48B family
EGK70_012160	COG1162	GTPase activity
EGK70_012170	COG0335	large ribosomal subunit rRNA binding
EGK70_012190	COG0450	alkyl hydroperoxide reductase
EGK70_012195	COG1960	acyl-CoA dehydrogenase activity
EGK70_012210	COG0123	including yeast histone deacetylase and acetoin utilization protein
EGK70_012215	COG2951	lytic endotransglycosylase activity
EGK70_012230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGK70_012235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EGK70_012240	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGK70_012260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EGK70_012265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGK70_012270	COG0287	Prephenate dehydrogenase
EGK70_012280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EGK70_012295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGK70_012315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGK70_012325	COG4771	TonB-dependent receptor
EGK70_012340	COG0753	catalase activity
EGK70_012350	COG4335	DNA alkylation repair
EGK70_012355	COG1846	Transcriptional regulator
EGK70_012360	COG0436	Aminotransferase
EGK70_012370	COG0251	oxidation-reduction process
EGK70_012375	COG1309	transcriptional regulator
EGK70_012410	COG0625	glutathione transferase activity
EGK70_012430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGK70_012440	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGK70_012550	COG2948	multi-organism process
EGK70_012585	COG0433	COG0433 Predicted ATPase
EGK70_012625	COG1475	DNA binding
EGK70_012660	COG4974	Belongs to the 'phage' integrase family
EGK70_012670	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EGK70_012675	COG1280	lysine exporter protein (LysE YggA)
EGK70_012700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGK70_012710	COG5002	protein histidine kinase activity
EGK70_012720	COG2046	Belongs to the sulfate adenylyltransferase family
EGK70_012725	COG2814	Major facilitator Superfamily
EGK70_012735	COG0583	DNA-binding transcription factor activity
EGK70_012740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EGK70_012760	COG0840	transmembrane signaling receptor activity
EGK70_012765	COG2119	membrane
EGK70_012780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGK70_012785	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGK70_012800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGK70_012805	COG2321	neutral zinc metallopeptidase
EGK70_012815	COG0347	Belongs to the P(II) protein family
EGK70_012820	COG0004	ammonium transporteR
EGK70_012825	COG3909	cytochrome
EGK70_012835	COG0625	glutathione transferase activity
EGK70_012840	COG0730	response to heat
EGK70_012845	COG0482	sulfurtransferase activity
EGK70_012850	COG0277	FAD linked oxidase domain protein
EGK70_012855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGK70_012860	COG2879	small protein
EGK70_012870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGK70_012875	COG0765	amino acid transport
EGK70_012880	COG0765	amino acid transport
EGK70_012885	COG1126	abc transporter atp-binding protein
EGK70_012895	COG5285	phytanoyl-CoA dioxygenase
EGK70_012900	COG0662	Cupin 2, conserved barrel domain protein
EGK70_012910	COG0456	acetyltransferase
EGK70_012915	COG1846	Transcriptional regulator
EGK70_012925	COG0312	modulator of DNA gyrase
EGK70_012940	COG0308	aminopeptidase N
EGK70_012945	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EGK70_012970	COG0473	3-isopropylmalate dehydrogenase activity
EGK70_012980	COG0433	COG0433 Predicted ATPase
EGK70_012985	COG0217	transcriptional regulatory protein
EGK70_012990	COG0151	Belongs to the GarS family
EGK70_013000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EGK70_013005	COG0799	negative regulation of ribosome biogenesis
EGK70_013010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EGK70_013015	COG0424	maF-like protein
EGK70_013035	COG0023	Translation Initiation Factor
EGK70_013045	COG2084	Dehydrogenase
EGK70_013050	COG0625	glutathione transferase activity
EGK70_013055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EGK70_013060	COG1047	Peptidyl-prolyl cis-trans
EGK70_013065	COG2003	Belongs to the UPF0758 family
EGK70_013070	COG1737	Transcriptional regulator
EGK70_013075	COG0477	Major facilitator Superfamily
EGK70_013085	COG2271	Major facilitator Superfamily
EGK70_013100	COG0534	Mate efflux family protein
EGK70_013105	COG4175	Glycine betaine
EGK70_013110	COG4176	ABC-type proline glycine betaine transport system permease component
EGK70_013120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGK70_013125	COG2814	Major facilitator Superfamily
EGK70_013130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EGK70_013135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGK70_013140	COG0495	leucyl-tRNA aminoacylation
EGK70_013155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EGK70_013160	COG1981	membrane
EGK70_013175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGK70_013185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EGK70_013190	COG0148	phosphopyruvate hydratase activity
EGK70_013200	COG2814	Major facilitator Superfamily
EGK70_013215	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EGK70_013220	COG0504	CTP synthase activity
EGK70_013255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGK70_013265	COG0791	NLP P60 protein
EGK70_013275	COG0583	DNA-binding transcription factor activity
EGK70_013285	COG0583	DNA-binding transcription factor activity
EGK70_013290	COG4774	siderophore transport
EGK70_013300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGK70_013315	COG1309	transcriptional regulator
EGK70_013325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EGK70_013340	COG1045	serine acetyltransferase
EGK70_013355	COG1381	Involved in DNA repair and RecF pathway recombination
EGK70_013360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGK70_013365	COG0571	ribonuclease III activity
EGK70_013380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGK70_013400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGK70_013405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGK70_013410	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_013415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGK70_013420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGK70_013430	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGK70_013435	COG1399	metal-binding, possibly nucleic acid-binding protein
EGK70_013440	COG0424	maF-like protein
EGK70_013450	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGK70_013455	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EGK70_013460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EGK70_013465	COG0546	phosphoglycolate phosphatase activity
EGK70_013470	COG0564	pseudouridine synthase activity
EGK70_013475	COG1530	ribonuclease E activity
EGK70_013480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EGK70_013485	COG0159	tryptophan synthase activity
EGK70_013490	COG0133	tryptophan synthase activity
EGK70_013495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGK70_013505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGK70_013510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGK70_013520	COG2878	Part of a membrane complex involved in electron transport
EGK70_013525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGK70_013535	COG3047	cAMP biosynthetic process
EGK70_013560	COG3039	Transposase
EGK70_013565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGK70_013570	COG2917	probably involved in intracellular septation
EGK70_013580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGK70_013585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGK70_013595	COG1196	nuclear chromosome segregation
EGK70_013605	COG1573	uracil-dna glycosylase
EGK70_013610	COG1214	PFAM Peptidase M22, glycoprotease
EGK70_013625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EGK70_013630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EGK70_013635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGK70_013640	COG0560	Phosphoserine phosphatase
EGK70_013655	COG1007	ATP synthesis coupled electron transport
EGK70_013670	COG0713	ATP synthesis coupled electron transport
EGK70_013680	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGK70_013685	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EGK70_013690	COG1034	ATP synthesis coupled electron transport
EGK70_013705	COG0649	NAD binding
EGK70_013710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGK70_013715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGK70_013720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGK70_013725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGK70_013740	COG0149	triose-phosphate isomerase activity
EGK70_013745	COG0604	alcohol dehydrogenase
EGK70_013765	COG1185	polyribonucleotide nucleotidyltransferase activity
EGK70_013770	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EGK70_013775	COG1183	phosphatidylcholine synthase activity
EGK70_013780	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EGK70_013785	COG0440	acetolactate synthase activity
EGK70_013790	COG0028	Belongs to the TPP enzyme family
EGK70_013795	COG1289	transmembrane transporter activity
EGK70_013800	COG3022	response to hydroperoxide
EGK70_013805	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_013835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGK70_013840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGK70_013845	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EGK70_013850	COG1674	ftsk spoiiie
EGK70_013855	COG0492	ferredoxin-NADP+ reductase activity
EGK70_013875	COG0477	Major facilitator Superfamily
EGK70_013895	COG2272	Belongs to the type-B carboxylesterase lipase family
EGK70_013900	COG1960	acyl-CoA dehydrogenase activity
EGK70_013925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGK70_013945	COG2204	response regulator
EGK70_013985	COG4964	Belongs to the GSP D family
EGK70_014045	COG0612	Peptidase, M16
EGK70_014050	COG0484	heat shock protein binding
EGK70_014055	COG0443	Heat shock 70 kDa protein
EGK70_014060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGK70_014065	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGK70_014070	COG1420	regulation of RNA biosynthetic process
EGK70_014080	COG0497	DNA recombination
EGK70_014085	COG0735	belongs to the Fur family
EGK70_014090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGK70_014105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EGK70_014125	COG0582	viral genome integration into host DNA
EGK70_014135	COG1396	sequence-specific DNA binding
EGK70_014140	COG0583	DNA-binding transcription factor activity
EGK70_014145	COG0589	response to stress
EGK70_014150	COG0659	secondary active sulfate transmembrane transporter activity
EGK70_014155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EGK70_014160	COG3039	Transposase
EGK70_014165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGK70_014170	COG0785	Cytochrome C biogenesis protein
EGK70_014200	COG3220	belongs to the UPF0276 family
EGK70_014235	COG3039	Transposase
EGK70_014245	COG1595	DNA-templated transcription, initiation
EGK70_014250	COG0431	NADPH-dependent FMN reductase
EGK70_014260	COG0798	PFAM Bile acid sodium symporter
EGK70_014315	COG0459	protein refolding
EGK70_014540	COG2003	Belongs to the UPF0758 family
EGK70_014590	COG0640	Transcriptional regulator
EGK70_014640	COG0629	single-stranded DNA binding
EGK70_014690	COG5001	Diguanylate cyclase
EGK70_014690	COG3300	MHYT domain
EGK70_014705	COG2814	Major facilitator Superfamily
EGK70_014720	COG3383	formate dehydrogenase (NAD+) activity
EGK70_014720	COG0243	molybdopterin cofactor binding
EGK70_014725	COG0437	4 iron, 4 sulfur cluster binding
EGK70_014730	COG2864	formate dehydrogenase
EGK70_014735	COG3058	Necessary for formate dehydrogenase activity
EGK70_014740	COG2819	hydrolase of the alpha beta superfamily
EGK70_014750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGK70_014750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGK70_014750	COG0506	proline dehydrogenase activity
EGK70_014765	COG2423	ornithine cyclodeaminase activity
EGK70_014770	COG0477	Major facilitator Superfamily
EGK70_014775	COG0513	Belongs to the DEAD box helicase family
EGK70_014780	COG3657	addiction module killer protein
EGK70_014785	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGK70_014790	COG0583	DNA-binding transcription factor activity
EGK70_014795	COG4638	Rieske (2fe-2S)
EGK70_014815	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGK70_014835	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EGK70_014840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGK70_014845	COG2814	Major facilitator Superfamily
EGK70_014860	COG0154	amidase activity
EGK70_014865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGK70_014870	COG2814	Major facilitator Superfamily
EGK70_014900	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_014910	COG0842	Transport permease protein
EGK70_014915	COG0842	Transport permease protein
EGK70_014915	COG1129	ABC transporter
EGK70_014920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGK70_014925	COG1538	Outer membrane efflux protein
EGK70_014930	COG3243	poly(R)-hydroxyalkanoic acid synthase
EGK70_014935	COG1309	transcriptional regulator
EGK70_014940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGK70_014945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGK70_014950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGK70_014965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGK70_014980	COG0505	Belongs to the CarA family
EGK70_014985	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EGK70_014995	COG0789	Transcriptional regulator
EGK70_015005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGK70_015050	COG3278	Belongs to the heme-copper respiratory oxidase family
EGK70_015055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGK70_015075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGK70_015155	COG0517	IMP dehydrogenase activity
EGK70_015155	COG0516	GMP reductase activity
EGK70_015170	COG1027	Aspartate ammonia-lyase
EGK70_015175	COG1846	Transcriptional regulator
EGK70_015185	COG0494	nUDIX hydrolase
EGK70_015190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EGK70_015195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EGK70_015210	COG1414	Transcriptional regulator
EGK70_015230	COG0513	Belongs to the DEAD box helicase family
EGK70_015250	COG0429	hydrolase of the alpha beta-hydrolase fold
EGK70_015275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGK70_015285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGK70_015295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EGK70_015300	COG0632	four-way junction helicase activity
EGK70_015310	COG2255	four-way junction helicase activity
EGK70_015320	COG0418	dihydroorotase activity
EGK70_015330	COG0415	Belongs to the DNA photolyase family
EGK70_015395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGK70_015430	COG1177	transmembrane transport
EGK70_015435	COG3842	ATPase activity
EGK70_015440	COG1840	ABC-type Fe3 transport system, periplasmic component
EGK70_015445	COG2084	Dehydrogenase
EGK70_015460	COG0494	nUDIX hydrolase
EGK70_015465	COG0442	prolyl-tRNA aminoacylation
EGK70_015470	COG0824	Thioesterase
EGK70_015475	COG0811	peptide transport
EGK70_015490	COG0823	Involved in the tonB-independent uptake of proteins
EGK70_015530	COG1079	Belongs to the binding-protein-dependent transport system permease family
EGK70_015535	COG4603	Belongs to the binding-protein-dependent transport system permease family
EGK70_015540	COG3845	ABC transporter
EGK70_015560	COG0427	acetyl-CoA hydrolase
EGK70_015565	COG0583	DNA-binding transcription factor activity
EGK70_015575	COG3634	alkyl hydroperoxide reductase activity
EGK70_015590	COG0697	spore germination
EGK70_015595	COG0175	sulfate reduction
EGK70_015605	COG2895	sulfate adenylyltransferase (ATP) activity
EGK70_015615	COG1012	belongs to the aldehyde dehydrogenase family
EGK70_015620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGK70_015625	COG5383	Protein conserved in bacteria
EGK70_015635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGK70_015650	COG0583	DNA-binding transcription factor activity
EGK70_015655	COG1741	Belongs to the pirin family
EGK70_015660	COG3706	GGDEF domain
EGK70_015665	COG0154	amidase activity
EGK70_015680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EGK70_015695	COG0284	orotidine-5'-phosphate decarboxylase activity
EGK70_015710	COG1414	Transcriptional regulator
EGK70_015720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGK70_015730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGK70_015735	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGK70_015760	COG0742	ribosomal rna small subunit methyltransferase
EGK70_015765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EGK70_015770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGK70_015800	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EGK70_015815	COG1335	isochorismatase
EGK70_015820	COG2309	aminopeptidase activity
EGK70_015825	COG0596	Alpha beta hydrolase
EGK70_015830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGK70_015830	COG2010	Cytochrome c
EGK70_015835	COG2080	2 iron, 2 sulfur cluster binding
EGK70_015840	COG2010	Cytochrome c
EGK70_015840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGK70_015850	COG0410	ABC transporter
EGK70_015855	COG0411	ABC transporter
EGK70_015865	COG0683	leucine binding
EGK70_015875	COG3706	GGDEF domain
EGK70_015890	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_015905	COG1234	tRNA 3'-trailer cleavage
EGK70_015910	COG2188	Transcriptional regulator
EGK70_015920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGK70_015930	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGK70_015930	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGK70_015935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EGK70_015935	COG3608	succinylglutamate desuccinylase aspartoacylase
EGK70_015940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EGK70_015965	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EGK70_015990	COG3328	transposase activity
EGK70_015995	COG1335	isochorismatase
EGK70_016000	COG2309	aminopeptidase activity
EGK70_016005	COG0596	Alpha beta hydrolase
EGK70_016020	COG1120	ATPase activity
EGK70_016025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGK70_016040	COG2031	fatty acid transporter
EGK70_016045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGK70_016060	COG3039	Transposase
EGK70_016070	COG1960	acyl-CoA dehydrogenase activity
EGK70_016095	COG1022	Amp-dependent synthetase and ligase
EGK70_016115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGK70_016120	COG1024	Enoyl-CoA hydratase
EGK70_016155	COG0443	Heat shock 70 kDa protein
EGK70_016210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGK70_016215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGK70_016220	COG0328	RNA-DNA hybrid ribonuclease activity
EGK70_016225	COG2226	methyltransferase
EGK70_016230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGK70_016235	COG0741	lytic transglycosylase activity
EGK70_016235	COG1388	LysM domain
EGK70_016245	COG2204	response regulator
EGK70_016250	COG4191	Histidine kinase
EGK70_016255	COG1301	dicarboxylic acid transport
EGK70_016265	COG1054	Belongs to the UPF0176 family
EGK70_016285	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGK70_016310	COG0604	alcohol dehydrogenase
EGK70_016320	COG1024	Enoyl-CoA hydratase
EGK70_016340	COG1902	pentaerythritol trinitrate reductase activity
EGK70_016365	COG0583	DNA-binding transcription factor activity
EGK70_016370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGK70_016375	COG1454	alcohol dehydrogenase
EGK70_016395	COG0583	DNA-binding transcription factor activity
EGK70_016430	COG1393	Belongs to the ArsC family
EGK70_016435	COG0431	NADPH-dependent FMN reductase
EGK70_016440	COG0745	RESPONSE REGULATOR receiver
EGK70_016445	COG0642	Histidine kinase
EGK70_016460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGK70_016460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGK70_016465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGK70_016470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EGK70_016475	COG1881	PFAM PEBP family protein
EGK70_016480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGK70_016485	COG0739	heme binding
EGK70_016490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EGK70_016495	COG0316	Belongs to the HesB IscA family
EGK70_016505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EGK70_016510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGK70_016515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGK70_016520	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EGK70_016525	COG0312	modulator of DNA gyrase
EGK70_016530	COG3028	Belongs to the UPF0307 family
EGK70_016555	COG4566	intracellular signal transduction
EGK70_016560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGK70_016565	COG4681	YaeQ
EGK70_016590	COG0762	integral membrane protein
EGK70_016600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGK70_016600	COG2169	Transcriptional regulator
EGK70_016605	COG3133	Outer membrane lipoprotein
EGK70_016610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGK70_016625	COG0439	Biotin carboxylase
EGK70_016630	COG0511	ligase activity, forming carbon-carbon bonds
EGK70_016635	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EGK70_016640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGK70_016645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGK70_016650	COG3150	esterase
EGK70_016665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGK70_016670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGK70_016680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGK70_016695	COG1678	Uncharacterized ACR, COG1678
EGK70_016710	COG0352	thiamine-phosphate diphosphorylase activity
EGK70_016715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EGK70_016725	COG3039	Transposase
EGK70_016735	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGK70_016745	COG3237	CsbD-like
EGK70_016750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EGK70_016755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGK70_016760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGK70_016765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EGK70_016790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGK70_016805	COG1126	abc transporter atp-binding protein
EGK70_016810	COG0765	amino acid transport
EGK70_016815	COG4597	amino acid ABC transporter
EGK70_016820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGK70_016825	COG2884	Cell division ATP-binding protein ftsE
EGK70_016830	COG2177	Part of the ABC transporter FtsEX involved in
EGK70_016840	COG0772	Belongs to the SEDS family
EGK70_016845	COG0768	penicillin binding
EGK70_016855	COG1792	Involved in formation and maintenance of cell shape
EGK70_016860	COG1077	Cell shape determining protein MreB Mrl
EGK70_016865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGK70_016870	COG0154	amidase activity
EGK70_016875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGK70_016880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EGK70_016885	COG0583	DNA-binding transcription factor activity
EGK70_016890	COG2259	Doxx family
EGK70_016895	COG3384	dioxygenase
EGK70_016905	COG3245	cytochrome
EGK70_016915	COG1846	Transcriptional regulator
EGK70_016920	COG1960	acyl-CoA dehydrogenase activity
EGK70_016925	COG2814	Major facilitator Superfamily
EGK70_016935	COG1024	Enoyl-CoA hydratase
EGK70_016945	COG3604	Transcriptional regulator
EGK70_016965	COG1309	transcriptional regulator
EGK70_016980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGK70_017005	COG1090	epimerase
EGK70_017010	COG0786	glutamate:sodium symporter activity
EGK70_017015	COG0142	geranyltranstransferase activity
EGK70_017025	COG0494	nUDIX hydrolase
EGK70_017030	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EGK70_017055	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EGK70_017060	COG0237	dephospho-CoA kinase activity
EGK70_017070	COG2197	response regulator
EGK70_017075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGK70_017080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGK70_017090	COG0477	Major facilitator Superfamily
EGK70_017120	COG4206	TonB-dependent receptor
EGK70_017125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGK70_017140	COG1595	DNA-templated transcription, initiation
EGK70_017150	COG2022	thiamine diphosphate biosynthetic process
EGK70_017155	COG0351	phosphomethylpyrimidine kinase
EGK70_017160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGK70_017165	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGK70_017170	COG1538	Outer membrane efflux protein
EGK70_017175	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EGK70_017185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGK70_017200	COG2226	methyltransferase
EGK70_017205	COG0745	RESPONSE REGULATOR receiver
EGK70_017210	COG5002	protein histidine kinase activity
EGK70_017220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGK70_017225	COG1984	allophanate hydrolase subunit 2
EGK70_017230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGK70_017235	COG1238	metal cluster binding
EGK70_017270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGK70_017275	COG4988	ABC transporter
EGK70_017285	COG1294	oxidase, subunit
EGK70_017290	COG1271	oxidase subunit
EGK70_017305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGK70_017320	COG1137	ATPase activity
EGK70_017330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGK70_017335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EGK70_017340	COG1660	Displays ATPase and GTPase activities
EGK70_017350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGK70_017355	COG0792	nuclease activity
EGK70_017360	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EGK70_017375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGK70_017395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGK70_017400	COG0793	Belongs to the peptidase S41A family
EGK70_017405	COG4942	peptidase
EGK70_017410	COG0588	phosphoglycerate mutase activity
EGK70_017415	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGK70_017425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EGK70_017435	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_017440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGK70_017445	COG1040	competence protein
EGK70_017450	COG2226	methyltransferase
EGK70_017460	COG2204	response regulator
EGK70_017480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGK70_017490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGK70_017495	COG3473	Maleate cis-trans isomerase
EGK70_017510	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EGK70_017525	COG0463	Glycosyl transferase, family 2
EGK70_017530	COG0438	transferase activity, transferring glycosyl groups
EGK70_017540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGK70_017565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGK70_017580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EGK70_017590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EGK70_017595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EGK70_017600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGK70_017615	COG0356	it plays a direct role in the translocation of protons across the membrane
EGK70_017625	COG1024	Enoyl-CoA hydratase
EGK70_017640	COG0037	tRNA processing
EGK70_017645	COG0163	prenyltransferase activity
EGK70_017650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGK70_017655	COG2890	protein-(glutamine-N5) methyltransferase activity
EGK70_017700	COG3180	Ammonia monooxygenase
EGK70_017720	COG3850	Histidine kinase
EGK70_017720	COG5002	protein histidine kinase activity
EGK70_017735	COG0477	Major facilitator Superfamily
EGK70_017740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGK70_017760	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EGK70_017790	COG0437	4 iron, 4 sulfur cluster binding
EGK70_017795	COG2864	formate dehydrogenase
EGK70_017805	COG1921	L-seryl-tRNASec selenium transferase activity
EGK70_017810	COG3276	selenocysteine insertion sequence binding
EGK70_017820	COG1476	TRANSCRIPTIONal
EGK70_017825	COG0235	Class ii aldolase
EGK70_017835	COG3181	Tripartite tricarboxylate transporter family receptor
EGK70_017850	COG0709	Synthesizes selenophosphate from selenide and ATP
EGK70_017855	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EGK70_017860	COG0348	domain, Protein
EGK70_017860	COG3901	Regulator of nitric oxide reductase transcription
EGK70_017865	COG4263	nitrous-oxide reductase activity
EGK70_017880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EGK70_017895	COG0166	Belongs to the GPI family
EGK70_017920	COG1215	transferase activity, transferring glycosyl groups
EGK70_017955	COG3039	Transposase
EGK70_017975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGK70_018010	COG0156	8-amino-7-oxononanoate synthase activity
EGK70_018015	COG0604	alcohol dehydrogenase
EGK70_018015	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_018015	COG3321	synthase
EGK70_018020	COG2233	PERMEase
EGK70_018025	COG0697	spore germination
EGK70_018030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGK70_018035	COG0697	spore germination
EGK70_018045	COG0183	Belongs to the thiolase family
EGK70_018050	COG1024	Enoyl-CoA hydratase
EGK70_018050	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGK70_018065	COG1127	ABC transporter
EGK70_018070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGK70_018075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGK70_018090	COG1131	(ABC) transporter
EGK70_018095	COG0842	Transport permease protein
EGK70_018105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGK70_018115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGK70_018120	COG0131	Imidazoleglycerol-phosphate dehydratase
EGK70_018130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EGK70_018135	COG0107	imidazoleglycerol-phosphate synthase activity
EGK70_018145	COG0140	phosphoribosyl-ATP diphosphatase activity
EGK70_018150	COG0537	adenosine 5'-monophosphoramidase activity
EGK70_018155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGK70_018160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGK70_018170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGK70_018180	COG1970	mechanosensitive ion channel activity
EGK70_018185	COG0723	plastoquinol--plastocyanin reductase activity
EGK70_018190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EGK70_018195	COG2857	Cytochrome c1
EGK70_018200	COG0625	glutathione transferase activity
EGK70_018205	COG2969	positive regulation of protein catabolic process
EGK70_018210	COG4208	sulfate ABC transporter
EGK70_018215	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGK70_018220	COG4150	thiosulfate binding
EGK70_018260	COG0789	Transcriptional regulator
EGK70_018285	COG0789	Transcriptional regulator
EGK70_018295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGK70_018320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGK70_018345	COG0582	viral genome integration into host DNA
EGK70_018360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGK70_018380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EGK70_018385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGK70_018390	COG3622	Belongs to the hyi family
EGK70_018395	COG2084	Dehydrogenase
EGK70_018400	COG0129	dihydroxy-acid dehydratase activity
EGK70_018405	COG1802	Transcriptional regulator
EGK70_018410	COG1522	sequence-specific DNA binding
EGK70_018420	COG3483	tryptophan 2,3-dioxygenase activity
EGK70_018440	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EGK70_018445	COG0656	L-ascorbic acid biosynthetic process
EGK70_018455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGK70_018460	COG3706	GGDEF domain
EGK70_018465	COG2226	methyltransferase
EGK70_018475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGK70_018490	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EGK70_018495	COG0583	DNA-binding transcription factor activity
EGK70_018500	COG1028	Short-chain dehydrogenase reductase Sdr
EGK70_018505	COG1335	isochorismatase
EGK70_018525	COG2823	Periplasmic or secreted lipoprotein
EGK70_018535	COG3284	Transcriptional regulator
EGK70_018565	COG1595	DNA-templated transcription, initiation
EGK70_018575	COG1522	sequence-specific DNA binding
EGK70_018585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGK70_018605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGK70_018645	COG0109	protoheme IX farnesyltransferase activity
EGK70_018650	COG3177	Filamentation induced by cAMP protein fic
EGK70_018690	COG3568	Endonuclease Exonuclease Phosphatase
EGK70_018695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGK70_018720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGK70_018730	COG1228	amidohydrolase
EGK70_018740	COG2986	histidine ammonia-lyase
EGK70_018745	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EGK70_018775	COG0789	Transcriptional regulator
EGK70_018795	COG0625	glutathione transferase activity
EGK70_018825	COG2365	Tyrosine phosphatase family
EGK70_018830	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EGK70_018850	COG2423	ornithine cyclodeaminase activity
EGK70_018900	COG3069	C4-dicarboxylate transmembrane transporter activity
EGK70_018910	COG1802	Transcriptional regulator
EGK70_018920	COG2814	Major facilitator Superfamily
EGK70_018935	COG2814	Major facilitator Superfamily
EGK70_018945	COG2814	Major facilitator Superfamily
EGK70_018955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EGK70_018980	COG5002	protein histidine kinase activity
EGK70_018980	COG5001	Diguanylate cyclase
EGK70_018985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGK70_018990	COG1333	cytochrome c biogenesis protein
EGK70_019000	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EGK70_019010	COG4232	protein-disulfide reductase activity
EGK70_019030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGK70_019035	COG0203	ribosomal protein L17
EGK70_019040	COG0202	RNA polymerase activity
EGK70_019045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGK70_019050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EGK70_019055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGK70_019060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGK70_019070	COG0201	protein transport
EGK70_019075	COG0200	Binds to the 23S rRNA
EGK70_019080	COG1841	ribosomal large subunit assembly
EGK70_019085	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGK70_019090	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EGK70_019095	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGK70_019100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGK70_019105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EGK70_019110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGK70_019115	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EGK70_019120	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGK70_019145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGK70_019150	COG2274	protein secretion by the type I secretion system
EGK70_019160	COG1538	Outer membrane efflux protein
EGK70_019185	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EGK70_019195	COG0647	UMP catabolic process
EGK70_019200	COG1737	Transcriptional regulator
EGK70_019215	COG1960	acyl-CoA dehydrogenase activity
EGK70_019220	COG0183	Belongs to the thiolase family
EGK70_019230	COG2067	long-chain fatty acid transport protein
EGK70_019245	COG0318	PFAM AMP-dependent synthetase and ligase
EGK70_019250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGK70_019255	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGK70_019260	COG1648	precorrin-2 dehydrogenase activity
EGK70_019260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGK70_019275	COG1116	anion transmembrane transporter activity
EGK70_019280	COG1960	acyl-CoA dehydrogenase activity
EGK70_019295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGK70_019300	COG0255	Belongs to the universal ribosomal protein uL29 family
EGK70_019305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGK70_019310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGK70_019315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EGK70_019320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGK70_019325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGK70_019330	COG0089	rRNA binding
EGK70_019335	COG0088	Forms part of the polypeptide exit tunnel
EGK70_019340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGK70_019345	COG4175	Glycine betaine
EGK70_019350	COG4176	ABC-type proline glycine betaine transport system permease component
EGK70_019355	COG0051	transcription antitermination factor activity, RNA binding
EGK70_019360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGK70_019365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EGK70_019370	COG0049	tRNA binding
EGK70_019375	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGK70_019405	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EGK70_019410	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGK70_019415	COG0085	RNA polymerase activity
EGK70_019420	COG0222	ribosome binding
EGK70_019425	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGK70_019430	COG0081	regulation of translation
EGK70_019455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGK70_019475	COG1475	DNA binding
EGK70_019480	COG1192	Involved in chromosome partitioning
EGK70_019485	COG0357	Ribosomal RNA small subunit methyltransferase G
EGK70_019490	COG0445	tRNA wobble uridine modification
EGK70_019495	COG0436	Aminotransferase
EGK70_019500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGK70_019505	COG3706	GGDEF domain
EGK70_019510	COG0688	phosphatidylethanolamine metabolic process
EGK70_019520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGK70_019565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EGK70_019610	COG0753	catalase activity
EGK70_019615	COG0706	membrane insertase activity
EGK70_019620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGK70_019625	COG0594	ribonuclease P activity
EGK70_019630	COG0230	Belongs to the bacterial ribosomal protein bL34 family