locus-tag	class	description
EYC51_00015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_00020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_00050	COG2003	Belongs to the UPF0758 family
EYC51_00100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYC51_00155	COG2894	cell division
EYC51_00215	COG3501	Rhs element vgr protein
EYC51_00285	COG3038	cytochrome b561
EYC51_00300	COG1393	Belongs to the ArsC family
EYC51_00305	COG0625	glutathione transferase activity
EYC51_00325	COG0084	hydrolase, TatD family'
EYC51_00340	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYC51_00345	COG0354	folic acid binding
EYC51_00360	COG1960	acyl-CoA dehydrogenase activity
EYC51_00365	COG2914	Belongs to the UPF0125 (RnfH) family
EYC51_00370	COG2867	negative regulation of translational initiation
EYC51_00375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYC51_00380	COG1252	NADH dehydrogenase
EYC51_00395	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYC51_00400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC51_00405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYC51_00410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC51_00420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYC51_00425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC51_00435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC51_00445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYC51_00450	COG0575	Belongs to the CDS family
EYC51_00455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYC51_00460	COG0233	cytoplasmic translational termination
EYC51_00465	COG0528	UMP kinase activity
EYC51_00470	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYC51_00475	COG0052	Belongs to the universal ribosomal protein uS2 family
EYC51_00480	COG0024	Methionine aminopeptidase
EYC51_00485	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EYC51_00505	COG1286	toxin biosynthetic process
EYC51_00515	COG0285	dihydrofolate synthase activity
EYC51_00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC51_00525	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC51_00530	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EYC51_00540	COG4566	intracellular signal transduction
EYC51_00545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYC51_00555	COG1999	signal sequence binding
EYC51_00575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYC51_00585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_00595	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EYC51_00615	COG0183	Belongs to the thiolase family
EYC51_00630	COG0583	DNA-binding transcription factor activity
EYC51_00655	COG0194	GDP metabolic process
EYC51_00660	COG1758	RNA polymerase activity
EYC51_00665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC51_00675	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EYC51_00680	COG0739	heme binding
EYC51_00685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_00690	COG0584	glycerophosphoryl diester phosphodiesterase
EYC51_00695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYC51_00700	COG1187	pseudouridine synthase activity
EYC51_00705	COG3161	chorismate lyase activity
EYC51_00710	COG2814	Major facilitator Superfamily
EYC51_00715	COG0656	L-ascorbic acid biosynthetic process
EYC51_00725	COG0668	transmembrane transport
EYC51_00730	COG0165	Argininosuccinate lyase
EYC51_00735	COG1940	carbohydrate kinase activity
EYC51_00735	COG1846	Transcriptional regulator
EYC51_00745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_00755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYC51_00765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC51_00770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYC51_00775	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EYC51_00780	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYC51_00785	COG2252	PERMEase
EYC51_00790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_00810	COG0488	(ABC) transporter
EYC51_00815	COG1619	proteins homologs of microcin C7 resistance protein MccF
EYC51_00820	COG0590	tRNA wobble adenosine to inosine editing
EYC51_00825	COG1131	(ABC) transporter
EYC51_00830	COG0842	Transport permease protein
EYC51_00845	COG0697	spore germination
EYC51_00865	COG1666	GTP binding
EYC51_00870	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_00875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYC51_00880	COG0519	Catalyzes the synthesis of GMP from XMP
EYC51_00880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC51_00885	COG2207	Transcriptional regulator
EYC51_00895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_00900	COG0135	phosphoribosylanthranilate isomerase activity
EYC51_00905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_00915	COG0101	tRNA pseudouridine synthase activity
EYC51_00925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYC51_00930	COG0473	3-isopropylmalate dehydrogenase activity
EYC51_00935	COG0066	3-isopropylmalate dehydratase activity
EYC51_00940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYC51_00950	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYC51_00955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYC51_00965	COG1295	ribonuclease BN
EYC51_00975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYC51_00980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYC51_01010	COG4964	Belongs to the GSP D family
EYC51_01045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYC51_01055	COG2959	enzyme of heme biosynthesis
EYC51_01065	COG0181	hydroxymethylbilane synthase activity
EYC51_01070	COG0861	Integral membrane protein TerC family
EYC51_01075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYC51_01080	COG0045	succinate-CoA ligase (ADP-forming) activity
EYC51_01090	COG0583	DNA-binding transcription factor activity
EYC51_01095	COG2137	regulation of response to DNA damage stimulus
EYC51_01100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYC51_01115	COG0477	Major facilitator Superfamily
EYC51_01130	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_01135	COG1024	Enoyl-CoA hydratase
EYC51_01140	COG3162	membrane
EYC51_01145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC51_01155	COG0540	Belongs to the ATCase OTCase family
EYC51_01170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC51_01185	COG2070	2-Nitropropane dioxygenase
EYC51_01190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC51_01195	COG2111	Na H antiporter
EYC51_01195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYC51_01200	COG1006	Multisubunit Na H antiporter MnhC subunit
EYC51_01205	COG0651	ATP synthesis coupled electron transport
EYC51_01215	COG2212	antiporter activity
EYC51_01230	COG3158	transport of potassium into the cell
EYC51_01235	COG0642	Histidine kinase
EYC51_01260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC51_01265	COG4208	sulfate ABC transporter
EYC51_01270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC51_01275	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYC51_01285	COG1278	Cold shock
EYC51_01295	COG0776	regulation of translation
EYC51_01305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC51_01305	COG1648	precorrin-2 dehydrogenase activity
EYC51_01310	COG2010	Cytochrome c
EYC51_01340	COG1648	precorrin-2 dehydrogenase activity
EYC51_01340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC51_01350	COG2010	Cytochrome c
EYC51_01355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_01365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYC51_01370	COG0557	exoribonuclease II activity
EYC51_01395	COG2375	cellular response to nickel ion
EYC51_01425	COG0583	DNA-binding transcription factor activity
EYC51_01430	COG3842	ATPase activity
EYC51_01440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC51_01445	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC51_01465	COG0412	Dienelactone hydrolase
EYC51_01470	COG3530	Putative quorum-sensing-regulated virulence factor
EYC51_01475	COG0625	glutathione transferase activity
EYC51_01480	COG1741	Belongs to the pirin family
EYC51_01490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_01495	COG2814	Major facilitator Superfamily
EYC51_01500	COG2807	transmembrane transport
EYC51_01505	COG2207	Transcriptional regulator
EYC51_01510	COG3135	benzoate transporter
EYC51_01520	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EYC51_01545	COG0402	S-adenosylhomocysteine deaminase activity
EYC51_01555	COG0745	RESPONSE REGULATOR receiver
EYC51_01560	COG2205	protein histidine kinase activity
EYC51_01565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYC51_01575	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYC51_01580	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EYC51_01585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYC51_01590	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EYC51_01595	COG0330	HflC and HflK could
EYC51_01600	COG0330	HflC and HflK could
EYC51_01605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYC51_01610	COG1923	regulation of RNA biosynthetic process
EYC51_01620	COG1160	GTP binding
EYC51_01625	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC51_01630	COG2976	Protein conserved in bacteria
EYC51_01635	COG0124	histidyl-tRNA synthetase
EYC51_01640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYC51_01650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYC51_01655	COG0105	UTP biosynthetic process
EYC51_01665	COG0336	Belongs to the RNA methyltransferase TrmD family
EYC51_01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYC51_01675	COG0228	four-way junction DNA binding
EYC51_01680	COG0425	Belongs to the sulfur carrier protein TusA family
EYC51_01685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC51_01700	COG2351	hydroxyisourate hydrolase activity
EYC51_01725	COG1653	transport
EYC51_01730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_01755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYC51_01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYC51_01790	COG0601	transmembrane transport
EYC51_01820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EYC51_01825	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYC51_01830	COG0542	response to heat
EYC51_01835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYC51_01850	COG0348	domain, Protein
EYC51_01870	COG3278	Belongs to the heme-copper respiratory oxidase family
EYC51_01880	COG2217	Heavy metal translocating P-type atpase
EYC51_01885	COG2224	Isocitrate lyase
EYC51_01890	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC51_01890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYC51_01905	COG0322	excinuclease ABC activity
EYC51_01910	COG1472	Belongs to the glycosyl hydrolase 3 family
EYC51_01915	COG0736	holo-[acyl-carrier-protein] synthase activity
EYC51_01925	COG2050	protein possibly involved in aromatic compounds catabolism
EYC51_01930	COG1024	Enoyl-CoA hydratase
EYC51_01935	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_01940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYC51_01945	COG2151	metal-sulfur cluster biosynthetic enzyme
EYC51_01950	COG3396	Phenylacetate-CoA oxygenase
EYC51_01955	COG3460	Phenylacetate-CoA oxygenase
EYC51_01960	COG3396	Phenylacetate-CoA oxygenase
EYC51_01965	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EYC51_01970	COG0501	Belongs to the peptidase M48B family
EYC51_01975	COG1162	GTPase activity
EYC51_01985	COG0335	large ribosomal subunit rRNA binding
EYC51_02005	COG0450	alkyl hydroperoxide reductase
EYC51_02010	COG1960	acyl-CoA dehydrogenase activity
EYC51_02030	COG2951	lytic endotransglycosylase activity
EYC51_02045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC51_02050	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EYC51_02055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EYC51_02075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYC51_02080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYC51_02085	COG0287	Prephenate dehydrogenase
EYC51_02095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYC51_02110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYC51_02130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC51_02150	COG0753	catalase activity
EYC51_02160	COG4335	DNA alkylation repair
EYC51_02170	COG0436	Aminotransferase
EYC51_02180	COG0251	oxidation-reduction process
EYC51_02195	COG0625	glutathione transferase activity
EYC51_02205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC51_02210	COG0697	spore germination
EYC51_02220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYC51_02225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_02240	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EYC51_02245	COG1280	lysine exporter protein (LysE YggA)
EYC51_02265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC51_02275	COG0784	Response regulator, receiver
EYC51_02275	COG2198	Histidine kinase
EYC51_02275	COG2205	protein histidine kinase activity
EYC51_02280	COG2046	Belongs to the sulfate adenylyltransferase family
EYC51_02285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYC51_02300	COG0840	transmembrane signaling receptor activity
EYC51_02305	COG2119	membrane
EYC51_02320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYC51_02325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYC51_02340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC51_02345	COG2321	neutral zinc metallopeptidase
EYC51_02355	COG0347	Belongs to the P(II) protein family
EYC51_02360	COG0004	ammonium transporteR
EYC51_02365	COG3909	cytochrome
EYC51_02375	COG0625	glutathione transferase activity
EYC51_02390	COG0730	response to heat
EYC51_02395	COG0482	sulfurtransferase activity
EYC51_02400	COG0277	FAD linked oxidase domain protein
EYC51_02405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYC51_02410	COG2879	small protein
EYC51_02415	COG1966	Carbon starvation protein
EYC51_02420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_02425	COG0765	amino acid transport
EYC51_02430	COG0765	amino acid transport
EYC51_02435	COG1126	abc transporter atp-binding protein
EYC51_02440	COG5285	phytanoyl-CoA dioxygenase
EYC51_02445	COG0662	Cupin 2, conserved barrel domain protein
EYC51_02450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EYC51_02455	COG0456	acetyltransferase
EYC51_02460	COG1846	Transcriptional regulator
EYC51_02470	COG0312	modulator of DNA gyrase
EYC51_02485	COG0308	aminopeptidase N
EYC51_02490	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EYC51_02505	COG0473	3-isopropylmalate dehydrogenase activity
EYC51_02510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC51_02515	COG0433	COG0433 Predicted ATPase
EYC51_02520	COG0217	transcriptional regulatory protein
EYC51_02525	COG0151	Belongs to the GarS family
EYC51_02530	COG0408	coproporphyrinogen oxidase activity
EYC51_02535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYC51_02540	COG0799	negative regulation of ribosome biogenesis
EYC51_02545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYC51_02550	COG0424	maF-like protein
EYC51_02570	COG0023	Translation Initiation Factor
EYC51_02580	COG2084	Dehydrogenase
EYC51_02585	COG0625	glutathione transferase activity
EYC51_02590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYC51_02595	COG1047	Peptidyl-prolyl cis-trans
EYC51_02600	COG2003	Belongs to the UPF0758 family
EYC51_02605	COG1737	Transcriptional regulator
EYC51_02610	COG0477	Major facilitator Superfamily
EYC51_02620	COG2271	Major facilitator Superfamily
EYC51_02625	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EYC51_02630	COG0254	rRNA binding
EYC51_02640	COG0534	Mate efflux family protein
EYC51_02645	COG4175	Glycine betaine
EYC51_02650	COG4176	ABC-type proline glycine betaine transport system permease component
EYC51_02660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC51_02665	COG2814	Major facilitator Superfamily
EYC51_02670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYC51_02675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYC51_02680	COG0495	leucyl-tRNA aminoacylation
EYC51_02690	COG1466	dna polymerase III delta subunit
EYC51_02695	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYC51_02715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYC51_02725	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYC51_02730	COG0148	phosphopyruvate hydratase activity
EYC51_02740	COG2814	Major facilitator Superfamily
EYC51_02760	COG0504	CTP synthase activity
EYC51_02790	COG0697	spore germination
EYC51_02795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYC51_02805	COG0791	NLP P60 protein
EYC51_02815	COG0583	DNA-binding transcription factor activity
EYC51_02825	COG0583	DNA-binding transcription factor activity
EYC51_02835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYC51_02850	COG1045	serine acetyltransferase
EYC51_02865	COG1381	Involved in DNA repair and RecF pathway recombination
EYC51_02870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYC51_02875	COG0571	ribonuclease III activity
EYC51_02885	COG0481	GTPase activity
EYC51_02890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC51_02915	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYC51_02925	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_02930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYC51_02935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYC51_02940	COG0416	fatty acid biosynthetic process
EYC51_02945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYC51_02950	COG1399	metal-binding, possibly nucleic acid-binding protein
EYC51_02955	COG0424	maF-like protein
EYC51_02965	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC51_02970	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EYC51_02975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYC51_02980	COG0546	phosphoglycolate phosphatase activity
EYC51_02990	COG1530	ribonuclease E activity
EYC51_02995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYC51_03000	COG0159	tryptophan synthase activity
EYC51_03005	COG0133	tryptophan synthase activity
EYC51_03010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYC51_03020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYC51_03025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYC51_03035	COG2878	Part of a membrane complex involved in electron transport
EYC51_03040	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYC51_03045	COG1129	ABC transporter
EYC51_03050	COG3047	cAMP biosynthetic process
EYC51_03060	COG0411	ABC transporter
EYC51_03075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC51_03080	COG2917	probably involved in intracellular septation
EYC51_03090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_03095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYC51_03105	COG1196	nuclear chromosome segregation
EYC51_03110	COG0477	Major facilitator Superfamily
EYC51_03115	COG1573	uracil-dna glycosylase
EYC51_03120	COG1214	PFAM Peptidase M22, glycoprotease
EYC51_03125	COG0745	RESPONSE REGULATOR receiver
EYC51_03130	COG2205	protein histidine kinase activity
EYC51_03135	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYC51_03140	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYC51_03145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYC51_03150	COG0560	Phosphoserine phosphatase
EYC51_03165	COG1007	ATP synthesis coupled electron transport
EYC51_03180	COG0713	ATP synthesis coupled electron transport
EYC51_03190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_03195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYC51_03215	COG0649	NAD binding
EYC51_03220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_03225	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_03230	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYC51_03235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EYC51_03250	COG0149	triose-phosphate isomerase activity
EYC51_03275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYC51_03280	COG1183	phosphatidylcholine synthase activity
EYC51_03285	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYC51_03290	COG0440	acetolactate synthase activity
EYC51_03295	COG0028	Belongs to the TPP enzyme family
EYC51_03300	COG1289	transmembrane transporter activity
EYC51_03305	COG3022	response to hydroperoxide
EYC51_03310	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_03320	COG2135	peptidase activity
EYC51_03380	COG3299	homolog of phage Mu protein gp47
EYC51_03420	COG4386	tail sheath protein
EYC51_03460	COG0740	serine-type endopeptidase activity
EYC51_03470	COG4626	Terminase
EYC51_03470	COG1802	Transcriptional regulator
EYC51_03545	COG1475	DNA binding
EYC51_03555	COG0582	viral genome integration into host DNA
EYC51_03575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYC51_03580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYC51_03585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EYC51_03590	COG1674	ftsk spoiiie
EYC51_03595	COG0492	ferredoxin-NADP+ reductase activity
EYC51_03615	COG0477	Major facilitator Superfamily
EYC51_03635	COG2272	Belongs to the type-B carboxylesterase lipase family
EYC51_03640	COG1960	acyl-CoA dehydrogenase activity
EYC51_03665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYC51_03685	COG2204	response regulator
EYC51_03725	COG4964	Belongs to the GSP D family
EYC51_03780	COG0612	Peptidase, M16
EYC51_03785	COG0484	heat shock protein binding
EYC51_03790	COG0443	Heat shock 70 kDa protein
EYC51_03795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYC51_03800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYC51_03805	COG1420	regulation of RNA biosynthetic process
EYC51_03810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYC51_03815	COG0497	DNA recombination
EYC51_03820	COG0735	belongs to the Fur family
EYC51_03825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYC51_03830	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYC51_03845	COG2267	carboxylic ester hydrolase activity
EYC51_03855	COG0477	Major facilitator Superfamily
EYC51_03860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYC51_03880	COG5001	Diguanylate cyclase
EYC51_03880	COG3300	MHYT domain
EYC51_03895	COG2819	hydrolase of the alpha beta superfamily
EYC51_03900	COG1454	alcohol dehydrogenase
EYC51_03920	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_03935	COG1414	Transcriptional regulator
EYC51_03940	COG0513	Belongs to the DEAD box helicase family
EYC51_03945	COG0583	DNA-binding transcription factor activity
EYC51_03950	COG4638	Rieske (2fe-2S)
EYC51_03955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EYC51_03970	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC51_03990	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EYC51_03995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYC51_04000	COG2814	Major facilitator Superfamily
EYC51_04015	COG0154	amidase activity
EYC51_04030	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_04040	COG0842	Transport permease protein
EYC51_04045	COG0842	Transport permease protein
EYC51_04045	COG1129	ABC transporter
EYC51_04050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_04055	COG1538	Outer membrane efflux protein
EYC51_04060	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC51_04070	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYC51_04075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYC51_04085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC51_04090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYC51_04100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC51_04115	COG0505	Belongs to the CarA family
EYC51_04120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYC51_04140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_04255	COG0517	IMP dehydrogenase activity
EYC51_04255	COG0516	GMP reductase activity
EYC51_04265	COG1027	Aspartate ammonia-lyase
EYC51_04270	COG1846	Transcriptional regulator
EYC51_04280	COG0494	nUDIX hydrolase
EYC51_04285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EYC51_04290	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYC51_04305	COG1414	Transcriptional regulator
EYC51_04325	COG0513	Belongs to the DEAD box helicase family
EYC51_04345	COG0429	hydrolase of the alpha beta-hydrolase fold
EYC51_04350	COG4783	chaperone-mediated protein folding
EYC51_04370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_04380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EYC51_04390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYC51_04395	COG0632	four-way junction helicase activity
EYC51_04405	COG2255	four-way junction helicase activity
EYC51_04415	COG0418	dihydroorotase activity
EYC51_04425	COG0415	Belongs to the DNA photolyase family
EYC51_04465	COG2897	thiosulfate sulfurtransferase activity
EYC51_04480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYC51_04485	COG4654	Cytochrome c, class I
EYC51_04520	COG1177	transmembrane transport
EYC51_04525	COG3842	ATPase activity
EYC51_04530	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC51_04535	COG2084	Dehydrogenase
EYC51_04550	COG0494	nUDIX hydrolase
EYC51_04555	COG0442	prolyl-tRNA aminoacylation
EYC51_04560	COG0824	Thioesterase
EYC51_04565	COG0811	peptide transport
EYC51_04570	COG0848	biopolymer transport protein
EYC51_04580	COG0823	Involved in the tonB-independent uptake of proteins
EYC51_04595	COG0596	Alpha beta hydrolase
EYC51_04610	COG0534	Mate efflux family protein
EYC51_04630	COG1129	ABC transporter
EYC51_04650	COG0427	acetyl-CoA hydrolase
EYC51_04655	COG0583	DNA-binding transcription factor activity
EYC51_04665	COG3634	alkyl hydroperoxide reductase activity
EYC51_04680	COG0697	spore germination
EYC51_04685	COG0175	sulfate reduction
EYC51_04695	COG2895	sulfate adenylyltransferase (ATP) activity
EYC51_04705	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_04710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_04715	COG5383	Protein conserved in bacteria
EYC51_04725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYC51_04740	COG0583	DNA-binding transcription factor activity
EYC51_04745	COG1741	Belongs to the pirin family
EYC51_04750	COG3706	GGDEF domain
EYC51_04755	COG0154	amidase activity
EYC51_04760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYC51_04765	COG0459	protein refolding
EYC51_04770	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYC51_04775	COG0284	orotidine-5'-phosphate decarboxylase activity
EYC51_04790	COG1414	Transcriptional regulator
EYC51_04800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EYC51_04810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC51_04815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYC51_04840	COG0742	ribosomal rna small subunit methyltransferase
EYC51_04845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYC51_04850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYC51_04880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EYC51_04895	COG1335	isochorismatase
EYC51_04900	COG2309	aminopeptidase activity
EYC51_04905	COG0596	Alpha beta hydrolase
EYC51_04910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC51_04910	COG2010	Cytochrome c
EYC51_04915	COG2080	2 iron, 2 sulfur cluster binding
EYC51_04920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYC51_04920	COG2010	Cytochrome c
EYC51_04930	COG0410	ABC transporter
EYC51_04935	COG0411	ABC transporter
EYC51_04960	COG5001	Diguanylate cyclase
EYC51_04960	COG3300	MHYT domain
EYC51_04975	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_04985	COG1234	tRNA 3'-trailer cleavage
EYC51_05000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYC51_05010	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYC51_05010	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYC51_05015	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYC51_05015	COG3608	succinylglutamate desuccinylase aspartoacylase
EYC51_05020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_05045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYC51_05070	COG1335	isochorismatase
EYC51_05075	COG2309	aminopeptidase activity
EYC51_05080	COG0596	Alpha beta hydrolase
EYC51_05095	COG2031	fatty acid transporter
EYC51_05105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYC51_05110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_05115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_05120	COG0328	RNA-DNA hybrid ribonuclease activity
EYC51_05125	COG2226	methyltransferase
EYC51_05130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYC51_05135	COG0741	lytic transglycosylase activity
EYC51_05135	COG1388	LysM domain
EYC51_05145	COG2204	response regulator
EYC51_05150	COG4191	Histidine kinase
EYC51_05155	COG1301	dicarboxylic acid transport
EYC51_05185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYC51_05200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EYC51_05205	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EYC51_05220	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_05225	COG1877	trehalose-phosphatase activity
EYC51_05260	COG0604	alcohol dehydrogenase
EYC51_05270	COG1024	Enoyl-CoA hydratase
EYC51_05290	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EYC51_05330	COG1393	Belongs to the ArsC family
EYC51_05335	COG0431	NADPH-dependent FMN reductase
EYC51_05350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC51_05350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYC51_05355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYC51_05360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYC51_05365	COG1881	PFAM PEBP family protein
EYC51_05370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYC51_05375	COG0739	heme binding
EYC51_05380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EYC51_05385	COG0316	Belongs to the HesB IscA family
EYC51_05395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYC51_05400	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYC51_05405	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYC51_05410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYC51_05415	COG0312	modulator of DNA gyrase
EYC51_05420	COG3028	Belongs to the UPF0307 family
EYC51_05450	COG4566	intracellular signal transduction
EYC51_05455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC51_05460	COG4681	YaeQ
EYC51_05495	COG0762	integral membrane protein
EYC51_05505	COG3133	Outer membrane lipoprotein
EYC51_05520	COG2264	protein methyltransferase activity
EYC51_05525	COG0439	Biotin carboxylase
EYC51_05530	COG0511	ligase activity, forming carbon-carbon bonds
EYC51_05535	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYC51_05540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_05545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC51_05550	COG3150	esterase
EYC51_05565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYC51_05570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYC51_05580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC51_05590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYC51_05595	COG1678	Uncharacterized ACR, COG1678
EYC51_05615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYC51_05630	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYC51_05640	COG3237	CsbD-like
EYC51_05645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYC51_05650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYC51_05655	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYC51_05660	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYC51_05685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYC51_05700	COG1126	abc transporter atp-binding protein
EYC51_05705	COG0765	amino acid transport
EYC51_05710	COG4597	amino acid ABC transporter
EYC51_05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_05720	COG2884	Cell division ATP-binding protein ftsE
EYC51_05725	COG2177	Part of the ABC transporter FtsEX involved in
EYC51_05730	COG1194	a g-specific adenine glycosylase
EYC51_05735	COG0772	Belongs to the SEDS family
EYC51_05740	COG0768	penicillin binding
EYC51_05750	COG1792	Involved in formation and maintenance of cell shape
EYC51_05755	COG1077	Cell shape determining protein MreB Mrl
EYC51_05760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYC51_05765	COG0154	amidase activity
EYC51_05770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYC51_05780	COG0583	DNA-binding transcription factor activity
EYC51_05785	COG2259	Doxx family
EYC51_05790	COG3384	dioxygenase
EYC51_05815	COG3604	Transcriptional regulator
EYC51_05850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYC51_05870	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_05875	COG3046	protein related to deoxyribodipyrimidine photolyase
EYC51_05885	COG1090	epimerase
EYC51_05890	COG0786	glutamate:sodium symporter activity
EYC51_05895	COG0142	geranyltranstransferase activity
EYC51_05905	COG0494	nUDIX hydrolase
EYC51_05925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYC51_05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_05935	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EYC51_05940	COG0237	dephospho-CoA kinase activity
EYC51_05955	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYC51_05960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYC51_05970	COG0477	Major facilitator Superfamily
EYC51_05985	COG4206	TonB-dependent receptor
EYC51_05990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYC51_06005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EYC51_06010	COG2022	thiamine diphosphate biosynthetic process
EYC51_06015	COG0351	phosphomethylpyrimidine kinase
EYC51_06020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYC51_06025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYC51_06030	COG1538	Outer membrane efflux protein
EYC51_06035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYC51_06045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYC51_06060	COG2226	methyltransferase
EYC51_06065	COG0745	RESPONSE REGULATOR receiver
EYC51_06080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYC51_06085	COG1984	allophanate hydrolase subunit 2
EYC51_06090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC51_06095	COG1238	metal cluster binding
EYC51_06115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYC51_06120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYC51_06125	COG4988	ABC transporter
EYC51_06135	COG1294	oxidase, subunit
EYC51_06140	COG1271	oxidase subunit
EYC51_06155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYC51_06170	COG1137	ATPase activity
EYC51_06180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC51_06185	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EYC51_06190	COG1660	Displays ATPase and GTPase activities
EYC51_06200	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYC51_06205	COG0792	nuclease activity
EYC51_06210	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EYC51_06225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC51_06235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYC51_06240	COG0793	Belongs to the peptidase S41A family
EYC51_06245	COG4942	peptidase
EYC51_06250	COG0588	phosphoglycerate mutase activity
EYC51_06255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYC51_06265	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYC51_06270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYC51_06275	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_06280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYC51_06285	COG1040	competence protein
EYC51_06290	COG2226	methyltransferase
EYC51_06300	COG2204	response regulator
EYC51_06330	COG3473	Maleate cis-trans isomerase
EYC51_06345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC51_06400	COG0482	sulfurtransferase activity
EYC51_06405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYC51_06415	COG1086	Polysaccharide biosynthesis protein
EYC51_06440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC51_06465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EYC51_06480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYC51_06485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYC51_06490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYC51_06495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYC51_06500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYC51_06505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYC51_06515	COG0356	it plays a direct role in the translocation of protons across the membrane
EYC51_06525	COG1024	Enoyl-CoA hydratase
EYC51_06540	COG0037	tRNA processing
EYC51_06545	COG0163	prenyltransferase activity
EYC51_06550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYC51_06555	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC51_06565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYC51_06575	COG0582	viral genome integration into host DNA
EYC51_06645	COG2948	multi-organism process
EYC51_06650	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EYC51_06680	COG1674	ftsk spoiiie
EYC51_06680	COG1280	lysine exporter protein (LysE YggA)
EYC51_06750	COG2135	peptidase activity
EYC51_06755	COG0629	single-stranded DNA binding
EYC51_06780	COG2003	Belongs to the UPF0758 family
EYC51_06805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYC51_06810	COG2264	protein methyltransferase activity
EYC51_06825	COG3180	Ammonia monooxygenase
EYC51_06845	COG5002	protein histidine kinase activity
EYC51_06860	COG0477	Major facilitator Superfamily
EYC51_06865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_06870	COG0243	molybdopterin cofactor binding
EYC51_06870	COG3383	formate dehydrogenase (NAD+) activity
EYC51_06875	COG3383	formate dehydrogenase (NAD+) activity
EYC51_06875	COG0243	molybdopterin cofactor binding
EYC51_06880	COG0437	4 iron, 4 sulfur cluster binding
EYC51_06885	COG2864	formate dehydrogenase
EYC51_06900	COG3276	selenocysteine insertion sequence binding
EYC51_06910	COG0235	Class ii aldolase
EYC51_06915	COG4771	TonB-dependent receptor
EYC51_06925	COG0709	Synthesizes selenophosphate from selenide and ATP
EYC51_06930	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EYC51_06935	COG0348	domain, Protein
EYC51_06935	COG3901	Regulator of nitric oxide reductase transcription
EYC51_06940	COG4263	nitrous-oxide reductase activity
EYC51_06955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYC51_06970	COG0166	Belongs to the GPI family
EYC51_06990	COG1215	transferase activity, transferring glycosyl groups
EYC51_07025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC51_07060	COG0156	8-amino-7-oxononanoate synthase activity
EYC51_07070	COG2233	PERMEase
EYC51_07075	COG0697	spore germination
EYC51_07080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_07085	COG0697	spore germination
EYC51_07105	COG2885	chlorophyll binding
EYC51_07205	COG0183	Belongs to the thiolase family
EYC51_07210	COG1024	Enoyl-CoA hydratase
EYC51_07210	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_07220	COG2059	Chromate
EYC51_07225	COG1127	ABC transporter
EYC51_07230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC51_07235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EYC51_07250	COG1131	(ABC) transporter
EYC51_07255	COG0842	Transport permease protein
EYC51_07265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYC51_07270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYC51_07275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYC51_07280	COG0131	Imidazoleglycerol-phosphate dehydratase
EYC51_07290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYC51_07295	COG0107	imidazoleglycerol-phosphate synthase activity
EYC51_07300	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYC51_07305	COG0140	phosphoribosyl-ATP diphosphatase activity
EYC51_07310	COG0537	adenosine 5'-monophosphoramidase activity
EYC51_07315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYC51_07330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYC51_07340	COG1970	mechanosensitive ion channel activity
EYC51_07345	COG0723	plastoquinol--plastocyanin reductase activity
EYC51_07350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYC51_07355	COG2857	Cytochrome c1
EYC51_07360	COG0625	glutathione transferase activity
EYC51_07365	COG2969	positive regulation of protein catabolic process
EYC51_07370	COG4208	sulfate ABC transporter
EYC51_07375	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC51_07380	COG4150	thiosulfate binding
EYC51_07400	COG1522	sequence-specific DNA binding
EYC51_07405	COG3483	tryptophan 2,3-dioxygenase activity
EYC51_07420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYC51_07425	COG0656	L-ascorbic acid biosynthetic process
EYC51_07435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC51_07440	COG3706	GGDEF domain
EYC51_07445	COG2226	methyltransferase
EYC51_07455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_07470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYC51_07475	COG0583	DNA-binding transcription factor activity
EYC51_07480	COG0477	Major facilitator Superfamily
EYC51_07485	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_07490	COG1335	isochorismatase
EYC51_07510	COG2823	Periplasmic or secreted lipoprotein
EYC51_07520	COG3284	Transcriptional regulator
EYC51_07530	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYC51_07535	COG1522	sequence-specific DNA binding
EYC51_07545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYC51_07565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYC51_07595	COG1612	heme a metabolic process
EYC51_07600	COG0109	protoheme IX farnesyltransferase activity
EYC51_07640	COG3568	Endonuclease Exonuclease Phosphatase
EYC51_07645	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYC51_07670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_07680	COG1228	amidohydrolase
EYC51_07690	COG2986	histidine ammonia-lyase
EYC51_07695	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYC51_07740	COG0625	glutathione transferase activity
EYC51_07765	COG1448	Aminotransferase
EYC51_07770	COG2365	Tyrosine phosphatase family
EYC51_07775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYC51_07795	COG2423	ornithine cyclodeaminase activity
EYC51_07845	COG3069	C4-dicarboxylate transmembrane transporter activity
EYC51_07855	COG1802	Transcriptional regulator
EYC51_07870	COG2814	Major facilitator Superfamily
EYC51_07875	COG0629	single-stranded DNA binding
EYC51_07880	COG2814	Major facilitator Superfamily
EYC51_07890	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYC51_07895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYC51_07900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYC51_07920	COG5002	protein histidine kinase activity
EYC51_07920	COG5001	Diguanylate cyclase
EYC51_07925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC51_07930	COG1333	cytochrome c biogenesis protein
EYC51_07940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYC51_07945	COG0113	porphobilinogen synthase activity
EYC51_07950	COG4232	protein-disulfide reductase activity
EYC51_07970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC51_07975	COG0203	ribosomal protein L17
EYC51_07980	COG0202	RNA polymerase activity
EYC51_07985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYC51_07990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYC51_07995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYC51_08000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYC51_08010	COG0201	protein transport
EYC51_08015	COG0200	Binds to the 23S rRNA
EYC51_08020	COG1841	ribosomal large subunit assembly
EYC51_08025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYC51_08030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYC51_08035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYC51_08040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYC51_08045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYC51_08050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYC51_08055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYC51_08060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYC51_08085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_08100	COG1538	Outer membrane efflux protein
EYC51_08120	COG0183	Belongs to the thiolase family
EYC51_08125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_08125	COG1024	Enoyl-CoA hydratase
EYC51_08145	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_08150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYC51_08155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYC51_08160	COG1648	precorrin-2 dehydrogenase activity
EYC51_08160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYC51_08175	COG1116	anion transmembrane transporter activity
EYC51_08195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYC51_08200	COG0255	Belongs to the universal ribosomal protein uL29 family
EYC51_08205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYC51_08210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYC51_08215	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYC51_08220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYC51_08225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYC51_08230	COG0089	rRNA binding
EYC51_08235	COG0088	Forms part of the polypeptide exit tunnel
EYC51_08240	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYC51_08245	COG4175	Glycine betaine
EYC51_08255	COG0051	transcription antitermination factor activity, RNA binding
EYC51_08260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYC51_08265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYC51_08270	COG0049	tRNA binding
EYC51_08275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYC51_08280	COG0745	RESPONSE REGULATOR receiver
EYC51_08290	COG0642	Histidine kinase
EYC51_08305	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EYC51_08315	COG0085	RNA polymerase activity
EYC51_08320	COG0222	ribosome binding
EYC51_08325	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYC51_08330	COG0081	regulation of translation
EYC51_08335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYC51_08355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYC51_08375	COG1475	DNA binding
EYC51_08380	COG1192	Involved in chromosome partitioning
EYC51_08390	COG0445	tRNA wobble uridine modification
EYC51_08395	COG0436	Aminotransferase
EYC51_08400	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC51_08405	COG3706	GGDEF domain
EYC51_08410	COG0688	phosphatidylethanolamine metabolic process
EYC51_08420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYC51_08460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYC51_08500	COG0753	catalase activity
EYC51_08505	COG0706	membrane insertase activity
EYC51_08510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYC51_08515	COG0594	ribonuclease P activity
EYC51_08520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EYC51_08540	COG1187	pseudouridine synthase activity
EYC51_08545	COG1802	Transcriptional regulator
EYC51_08550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_08570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYC51_08575	COG0583	DNA-binding transcription factor activity
EYC51_08585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYC51_08595	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_08610	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_08620	COG0596	Alpha beta hydrolase
EYC51_08620	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC51_08625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYC51_08640	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_08650	COG0697	spore germination
EYC51_08655	COG0583	DNA-binding transcription factor activity
EYC51_08665	COG3842	ATPase activity
EYC51_08685	COG0523	cobalamin synthesis protein
EYC51_08700	COG0625	glutathione transferase activity
EYC51_08740	COG1846	Transcriptional regulator
EYC51_08760	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC51_08765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_08770	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EYC51_08805	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_08835	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_08845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_08860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_08875	COG4608	Belongs to the ABC transporter superfamily
EYC51_08880	COG0444	Belongs to the ABC transporter superfamily
EYC51_08885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYC51_08895	COG4166	transmembrane transport
EYC51_08900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_08905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYC51_08920	COG1464	Belongs to the NlpA lipoprotein family
EYC51_08925	COG1464	Belongs to the NlpA lipoprotein family
EYC51_08930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYC51_08935	COG2011	ABC-type metal ion transport system permease component
EYC51_08960	COG1464	Belongs to the NlpA lipoprotein family
EYC51_08970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYC51_08990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC51_08995	COG0431	NADPH-dependent FMN reductase
EYC51_09015	COG4149	molybdate abc transporter
EYC51_09025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EYC51_09030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYC51_09035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_09055	COG0028	Belongs to the TPP enzyme family
EYC51_09060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_09110	COG2922	Belongs to the Smg family
EYC51_09115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC51_09125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYC51_09130	COG0183	Belongs to the thiolase family
EYC51_09135	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EYC51_09140	COG1960	acyl-CoA dehydrogenase activity
EYC51_09160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC51_09170	COG0018	arginyl-trna synthetase
EYC51_09200	COG1982	Orn Lys Arg decarboxylase major
EYC51_09205	COG0531	amino acid
EYC51_09210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYC51_09220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EYC51_09225	COG0066	3-isopropylmalate dehydratase activity
EYC51_09230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYC51_09235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYC51_09240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYC51_09245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_09260	COG1335	isochorismatase
EYC51_09265	COG0583	DNA-binding transcription factor activity
EYC51_09285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYC51_09290	COG1280	lysine exporter protein (LysE YggA)
EYC51_09295	COG0513	Belongs to the DEAD box helicase family
EYC51_09305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EYC51_09320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYC51_09370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYC51_09375	COG1127	ABC transporter
EYC51_09395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYC51_09400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYC51_09410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_09440	COG0583	DNA-binding transcription factor activity
EYC51_09465	COG1254	Belongs to the acylphosphatase family
EYC51_09490	COG0252	asparaginase activity
EYC51_09515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYC51_09520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC51_09525	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_09540	COG0411	ABC transporter
EYC51_09545	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_09570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_09585	COG0758	DNA mediated transformation
EYC51_09590	COG0242	peptide deformylase activity
EYC51_09595	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYC51_09600	COG0697	spore germination
EYC51_09615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_09630	COG4336	lyase activity
EYC51_09635	COG0583	DNA-binding transcription factor activity
EYC51_09640	COG0859	PFAM glycosyl transferase family 9
EYC51_09650	COG1278	Cold shock
EYC51_09655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYC51_09660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYC51_09665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYC51_09665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYC51_09675	COG1686	Belongs to the peptidase S11 family
EYC51_09685	COG2921	Belongs to the UPF0250 family
EYC51_09690	COG0321	lipoyl(octanoyl) transferase activity
EYC51_09695	COG1024	Enoyl-CoA hydratase
EYC51_09700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EYC51_09710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYC51_09790	COG0134	indole-3-glycerol-phosphate synthase activity
EYC51_09795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYC51_09800	COG0512	Glutamine amidotransferase of anthranilate synthase
EYC51_09810	COG0546	phosphoglycolate phosphatase activity
EYC51_09825	COG2967	ApaG domain
EYC51_09835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_09840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC51_09850	COG0840	transmembrane signaling receptor activity
EYC51_09855	COG2382	esterase
EYC51_09860	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_09865	COG1535	isochorismatase
EYC51_09865	COG3433	isochorismatase activity
EYC51_09870	COG1169	isochorismate synthase
EYC51_09885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYC51_09890	COG3433	isochorismatase activity
EYC51_09890	COG1535	isochorismatase
EYC51_09895	COG1021	2,3-dihydroxybenzoate-AMP ligase
EYC51_09905	COG0410	ABC transporter
EYC51_09910	COG0411	ABC transporter
EYC51_09940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC51_09955	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_09975	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EYC51_09980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYC51_09990	COG0513	Belongs to the DEAD box helicase family
EYC51_09995	COG2814	Major facilitator Superfamily
EYC51_10015	COG1253	flavin adenine dinucleotide binding
EYC51_10045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYC51_10060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_10080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC51_10085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EYC51_10095	COG0583	DNA-binding transcription factor activity
EYC51_10100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_10105	COG1126	abc transporter atp-binding protein
EYC51_10110	COG0765	amino acid transport
EYC51_10115	COG0765	amino acid transport
EYC51_10145	COG3391	amine dehydrogenase activity
EYC51_10150	COG2259	Doxx family
EYC51_10155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC51_10180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EYC51_10185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYC51_10190	COG0210	DNA helicase
EYC51_10215	COG0070	glutamate synthase
EYC51_10215	COG0069	glutamate synthase activity
EYC51_10215	COG0067	glutamate synthase
EYC51_10220	COG1024	Enoyl-CoA hydratase
EYC51_10230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYC51_10235	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYC51_10260	COG2918	glutathione biosynthetic process
EYC51_10270	COG2197	response regulator
EYC51_10275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC51_10285	COG2223	nitrite transmembrane transporter activity
EYC51_10290	COG2860	membrane
EYC51_10295	COG1346	cytolysis
EYC51_10305	COG0251	oxidation-reduction process
EYC51_10310	COG0251	oxidation-reduction process
EYC51_10325	COG0745	RESPONSE REGULATOR receiver
EYC51_10335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYC51_10350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYC51_10365	COG2096	Adenosyltransferase
EYC51_10380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EYC51_10385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYC51_10390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYC51_10395	COG0523	cobalamin synthesis protein
EYC51_10400	COG0735	belongs to the Fur family
EYC51_10410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYC51_10420	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EYC51_10430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYC51_10435	COG1560	Kdo2-lipid A biosynthetic process
EYC51_10445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYC51_10450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYC51_10455	COG1950	PFAM Membrane protein of
EYC51_10460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYC51_10475	COG0617	tRNA 3'-terminal CCA addition
EYC51_10490	COG0275	rRNA processing
EYC51_10495	COG0730	response to heat
EYC51_10500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EYC51_10505	COG0129	dihydroxy-acid dehydratase activity
EYC51_10510	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYC51_10515	COG0628	permease
EYC51_10545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EYC51_10560	COG0210	DNA helicase
EYC51_10570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EYC51_10585	COG3685	Protein conserved in bacteria
EYC51_10605	COG0277	FAD linked oxidase domain protein
EYC51_10610	COG1304	FMN binding
EYC51_10615	COG2186	Transcriptional regulator
EYC51_10630	COG2188	Transcriptional regulator
EYC51_10635	COG1522	sequence-specific DNA binding
EYC51_10645	COG1113	amino acid transport
EYC51_10655	COG1349	DNA-binding transcription factor activity
EYC51_10675	COG0395	ABC-type sugar transport system, permease component
EYC51_10685	COG0861	Integral membrane protein TerC family
EYC51_10690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_10700	COG1671	Belongs to the UPF0178 family
EYC51_10710	COG1418	mRNA catabolic process
EYC51_10720	COG4948	Mandelate Racemase Muconate Lactonizing
EYC51_10735	COG0154	amidase activity
EYC51_10745	COG0583	DNA-binding transcription factor activity
EYC51_10770	COG0326	Molecular chaperone. Has ATPase activity
EYC51_10775	COG4774	siderophore transport
EYC51_10780	COG3128	pkhd-type hydroxylase
EYC51_10790	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYC51_10805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYC51_10810	COG1652	LysM domain
EYC51_10825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYC51_10845	COG0387	Pfam Sodium calcium exchanger
EYC51_10850	COG0745	RESPONSE REGULATOR receiver
EYC51_10850	COG3706	GGDEF domain
EYC51_10860	COG0477	Major facilitator Superfamily
EYC51_10865	COG0235	Class ii aldolase
EYC51_10880	COG3391	amine dehydrogenase activity
EYC51_10885	COG0590	tRNA wobble adenosine to inosine editing
EYC51_10890	COG3257	ureidoglycine aminohydrolase activity
EYC51_10895	COG0583	DNA-binding transcription factor activity
EYC51_10900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYC51_10905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC51_10905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC51_10915	COG0489	protein tyrosine kinase activity
EYC51_10930	COG0717	Belongs to the dCTP deaminase family
EYC51_10935	COG1982	Orn Lys Arg decarboxylase major
EYC51_10940	COG2081	HI0933 family
EYC51_10945	COG0509	glycine decarboxylation via glycine cleavage system
EYC51_10955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EYC51_10960	COG1765	OsmC-like protein
EYC51_10965	COG3278	Belongs to the heme-copper respiratory oxidase family
EYC51_10990	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EYC51_11000	COG0469	pyruvate kinase activity
EYC51_11005	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EYC51_11015	COG2084	Dehydrogenase
EYC51_11020	COG3622	Belongs to the hyi family
EYC51_11025	COG3960	tartronate-semialdehyde synthase activity
EYC51_11030	COG0583	DNA-binding transcription factor activity
EYC51_11040	COG2233	PERMEase
EYC51_11045	COG1942	4-Oxalocrotonate Tautomerase
EYC51_11055	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EYC51_11060	COG3195	allantoin biosynthetic process
EYC51_11060	COG3648	Uricase
EYC51_11070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC51_11075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYC51_11090	COG0438	transferase activity, transferring glycosyl groups
EYC51_11100	COG0438	transferase activity, transferring glycosyl groups
EYC51_11105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC51_11110	COG0277	FAD linked oxidase domain protein
EYC51_11120	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYC51_11125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EYC51_11135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_11145	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYC51_11155	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EYC51_11170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYC51_11175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYC51_11180	COG0193	aminoacyl-tRNA hydrolase activity
EYC51_11190	COG0012	GTP binding
EYC51_11200	COG0288	reversible hydration of carbon dioxide
EYC51_11205	COG0583	DNA-binding transcription factor activity
EYC51_11215	COG4133	protoheme IX ABC transporter activity
EYC51_11220	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYC51_11235	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EYC51_11245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYC51_11250	COG3088	subunit of a heme lyase
EYC51_11255	COG4235	cytochrome complex assembly
EYC51_11260	COG0785	Cytochrome C biogenesis protein
EYC51_11270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYC51_11270	COG2169	Transcriptional regulator
EYC51_11290	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_11300	COG0411	ABC transporter
EYC51_11305	COG0410	ABC transporter
EYC51_11310	COG1858	cytochrome C peroxidase
EYC51_11315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYC51_11325	COG1959	2 iron, 2 sulfur cluster binding
EYC51_11330	COG2346	COG2346, Truncated hemoglobins
EYC51_11375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYC51_11380	COG3383	formate dehydrogenase (NAD+) activity
EYC51_11395	COG1910	domain protein
EYC51_11400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYC51_11405	COG0746	molybdenum cofactor guanylyltransferase activity
EYC51_11410	COG0303	'Molybdopterin
EYC51_11415	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC51_11420	COG0314	molybdopterin synthase activity
EYC51_11430	COG0315	cyclic pyranopterin monophosphate synthase activity
EYC51_11460	COG0678	peroxiredoxin activity
EYC51_11475	COG0697	spore germination
EYC51_11480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYC51_11500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYC51_11530	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EYC51_11535	COG4535	Mg2 and Co2 transporter CorC
EYC51_11540	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYC51_11545	COG1702	phosphate starvation-inducible protein PhoH
EYC51_11550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYC51_11560	COG0024	Methionine aminopeptidase
EYC51_11565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC51_11570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYC51_11575	COG1862	Preprotein translocase
EYC51_11580	COG0343	queuine tRNA-ribosyltransferase activity
EYC51_11585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYC51_11590	COG2027	D-alanyl-D-alanine carboxypeptidase
EYC51_11595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYC51_11605	COG4575	ribosome binding
EYC51_11620	COG0583	DNA-binding transcription factor activity
EYC51_11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYC51_11650	COG0154	amidase activity
EYC51_11660	COG0477	Major facilitator Superfamily
EYC51_11670	COG0346	lactoylglutathione lyase activity
EYC51_11675	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYC51_11685	COG0436	Aminotransferase
EYC51_11695	COG0280	phosphate acetyltransferase
EYC51_11695	COG0281	malic enzyme
EYC51_11705	COG2732	(Barnase) inhibitor
EYC51_11710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYC51_11715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYC51_11720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC51_11745	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYC51_11755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYC51_11760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYC51_11765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EYC51_11770	COG0009	L-threonylcarbamoyladenylate synthase
EYC51_11780	COG2030	dehydratase
EYC51_11780	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_11785	COG1960	acyl-CoA dehydrogenase activity
EYC51_11795	COG0405	Gamma-glutamyltransferase
EYC51_11805	COG0579	oxidoreductase
EYC51_11810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYC51_11815	COG0259	pyridoxamine-phosphate oxidase activity
EYC51_11825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYC51_11840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYC51_11845	COG1215	transferase activity, transferring glycosyl groups
EYC51_11855	COG0488	(ABC) transporter
EYC51_11875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYC51_11880	COG2894	cell division
EYC51_11885	COG0850	regulation of cytokinetic process
EYC51_11890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYC51_11895	COG1271	oxidase subunit
EYC51_11900	COG1294	oxidase, subunit
EYC51_11905	COG0038	chloride channel
EYC51_11915	COG0514	ATP-dependent DNA helicase (RecQ)
EYC51_11920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC51_11925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYC51_11930	COG0633	Ferredoxin
EYC51_11935	COG0488	(ABC) transporter
EYC51_11945	COG2001	Belongs to the MraZ family
EYC51_11950	COG0275	rRNA processing
EYC51_11955	COG3116	cell division
EYC51_11965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYC51_11970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYC51_11975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYC51_11985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYC51_11990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYC51_11995	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYC51_12000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYC51_12015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYC51_12025	COG0739	heme binding
EYC51_12025	COG0741	lytic transglycosylase activity
EYC51_12025	COG1196	nuclear chromosome segregation
EYC51_12030	COG0653	protein targeting
EYC51_12040	COG2239	Acts as a magnesium transporter
EYC51_12045	COG1607	acyl-coa hydrolase
EYC51_12050	COG1473	amidohydrolase
EYC51_12055	COG0318	PFAM AMP-dependent synthetase and ligase
EYC51_12065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_12065	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EYC51_12080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYC51_12085	COG2011	ABC-type metal ion transport system permease component
EYC51_12095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_12105	COG0765	amino acid transport
EYC51_12110	COG1126	abc transporter atp-binding protein
EYC51_12130	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EYC51_12135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYC51_12140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYC51_12145	COG0700	Nucleoside recognition
EYC51_12160	COG0204	Acyl-transferase
EYC51_12165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EYC51_12170	COG0751	glycine-tRNA ligase activity
EYC51_12175	COG0752	glycyl-tRNA synthetase alpha subunit
EYC51_12205	COG1573	uracil-dna glycosylase
EYC51_12215	COG0617	tRNA 3'-terminal CCA addition
EYC51_12225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYC51_12230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYC51_12235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYC51_12240	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYC51_12245	COG0586	Pfam SNARE associated Golgi protein
EYC51_12250	COG1477	protein flavinylation
EYC51_12270	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYC51_12275	COG0802	atpase or kinase
EYC51_12285	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_12290	COG0280	phosphate acetyltransferase
EYC51_12290	COG0281	malic enzyme
EYC51_12295	COG0583	DNA-binding transcription factor activity
EYC51_12300	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_12305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC51_12350	COG1733	regulation of RNA biosynthetic process
EYC51_12355	COG2910	NAD(P)H-binding
EYC51_12360	COG2223	nitrite transmembrane transporter activity
EYC51_12370	COG4974	Belongs to the 'phage' integrase family
EYC51_12375	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYC51_12380	COG4149	molybdate abc transporter
EYC51_12385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC51_12400	COG1074	ATP-dependent DNA helicase activity
EYC51_12420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYC51_12435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYC51_12440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYC51_12445	COG0505	Belongs to the CarA family
EYC51_12450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYC51_12465	COG0406	alpha-ribazole phosphatase activity
EYC51_12470	COG2233	PERMEase
EYC51_12475	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYC51_12480	COG1534	Rna-binding protein
EYC51_12485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYC51_12490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYC51_12495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYC51_12500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYC51_12510	COG0248	Ppx GppA phosphatase
EYC51_12515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYC51_12535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYC51_12540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYC51_12555	COG0745	RESPONSE REGULATOR receiver
EYC51_12560	COG2205	protein histidine kinase activity
EYC51_12575	COG0583	DNA-binding transcription factor activity
EYC51_12590	COG1231	oxidoreductase activity
EYC51_12600	COG2323	membrane
EYC51_12610	COG1368	sulfuric ester hydrolase activity
EYC51_12640	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYC51_12645	COG3327	negative regulation of DNA-templated transcription, initiation
EYC51_12665	COG0009	L-threonylcarbamoyladenylate synthase
EYC51_12670	COG1994	Peptidase M50
EYC51_12675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYC51_12680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EYC51_12685	COG1595	DNA-templated transcription, initiation
EYC51_12695	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYC51_12705	COG0156	8-amino-7-oxononanoate synthase activity
EYC51_12710	COG2124	cytochrome p450
EYC51_12715	COG3135	benzoate transporter
EYC51_12720	COG2850	peptidyl-arginine hydroxylation
EYC51_12725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYC51_12750	COG0577	efflux transmembrane transporter activity
EYC51_12750	COG1136	(ABC) transporter
EYC51_12755	COG1538	Outer membrane efflux protein
EYC51_12760	COG0363	glucosamine-6-phosphate deaminase activity
EYC51_12765	COG1132	(ABC) transporter
EYC51_12780	COG0583	DNA-binding transcription factor activity
EYC51_12785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYC51_12795	COG0668	transmembrane transport
EYC51_12840	COG0154	amidase activity
EYC51_12845	COG2031	fatty acid transporter
EYC51_12855	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EYC51_12865	COG1253	flavin adenine dinucleotide binding
EYC51_12870	COG1968	undecaprenyl-diphosphatase activity
EYC51_12875	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYC51_12890	COG0215	cysteine-tRNA ligase activity
EYC51_12900	COG0825	malonyl-CoA metabolic process
EYC51_12905	COG0037	tRNA processing
EYC51_12925	COG0330	HflC and HflK could
EYC51_12935	COG4977	sequence-specific DNA binding
EYC51_12940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYC51_12960	COG4208	sulfate ABC transporter
EYC51_12965	COG3842	ATPase activity
EYC51_12970	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC51_12975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EYC51_12980	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EYC51_13005	COG1304	FMN binding
EYC51_13010	COG0435	Glutathione S-transferase
EYC51_13015	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYC51_13030	COG2094	Belongs to the DNA glycosylase MPG family
EYC51_13035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EYC51_13040	COG2363	Small membrane protein
EYC51_13045	COG0598	Magnesium transport protein CorA
EYC51_13050	COG1960	acyl-CoA dehydrogenase activity
EYC51_13060	COG0747	negative chemotaxis
EYC51_13070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYC51_13075	COG4172	Belongs to the ABC transporter superfamily
EYC51_13085	COG3284	Transcriptional regulator
EYC51_13090	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_13095	COG1454	alcohol dehydrogenase
EYC51_13100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYC51_13140	COG3829	transcription factor binding
EYC51_13145	COG0477	Major facilitator Superfamily
EYC51_13155	COG0039	L-malate dehydrogenase activity
EYC51_13160	COG2188	Transcriptional regulator
EYC51_13165	COG2009	succinate dehydrogenase
EYC51_13175	COG1053	succinate dehydrogenase
EYC51_13180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYC51_13185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EYC51_13190	COG0372	Belongs to the citrate synthase family
EYC51_13195	COG2186	Transcriptional regulator
EYC51_13200	COG1620	l-lactate permease
EYC51_13205	COG0280	phosphate acetyltransferase
EYC51_13205	COG0281	malic enzyme
EYC51_13210	COG0567	Dehydrogenase, E1 component
EYC51_13215	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYC51_13220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYC51_13225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYC51_13240	COG2183	response to ionizing radiation
EYC51_13245	COG1199	ATP-dependent helicase activity
EYC51_13250	COG0659	secondary active sulfate transmembrane transporter activity
EYC51_13260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYC51_13260	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EYC51_13290	COG0564	pseudouridine synthase activity
EYC51_13300	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYC51_13305	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_13310	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EYC51_13335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYC51_13340	COG1187	pseudouridine synthase activity
EYC51_13345	COG0779	Required for maturation of 30S ribosomal subunits
EYC51_13350	COG0195	Participates in both transcription termination and antitermination
EYC51_13350	COG2251	uridine kinase activity
EYC51_13355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYC51_13360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYC51_13365	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYC51_13375	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC51_13385	COG4160	amino acid transport
EYC51_13390	COG4215	(ABC) transporter
EYC51_13395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYC51_13410	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYC51_13415	COG0501	Belongs to the peptidase M48B family
EYC51_13430	COG1722	exodeoxyribonuclease VII activity
EYC51_13440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYC51_13445	COG1469	GTP cyclohydrolase I activity
EYC51_13450	COG0360	Binds together with S18 to 16S ribosomal RNA
EYC51_13455	COG2965	DNA replication, synthesis of RNA primer
EYC51_13460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYC51_13465	COG0359	binds to the 23S rRNA
EYC51_13470	COG0305	Participates in initiation and elongation during chromosome replication
EYC51_13480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYC51_13485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYC51_13490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYC51_13500	COG0436	Aminotransferase
EYC51_13515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYC51_13520	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EYC51_13525	COG1562	ergosterol biosynthetic process
EYC51_13530	COG1562	ergosterol biosynthetic process
EYC51_13535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYC51_13540	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_13565	COG3842	ATPase activity
EYC51_13570	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYC51_13575	COG1177	transmembrane transport
EYC51_13580	COG1393	Belongs to the ArsC family
EYC51_13585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EYC51_13590	COG0704	Plays a role in the regulation of phosphate uptake
EYC51_13595	COG5001	Diguanylate cyclase
EYC51_13595	COG4251	negative regulation of phosphorylation
EYC51_13595	COG2203	Gaf domain
EYC51_13595	COG3706	GGDEF domain
EYC51_13600	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EYC51_13605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EYC51_13605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYC51_13610	COG1643	Atp-dependent helicase
EYC51_13620	COG0438	transferase activity, transferring glycosyl groups
EYC51_13625	COG0726	polysaccharide deacetylase
EYC51_13640	COG0297	glycogen (starch) synthase activity
EYC51_13645	COG0438	transferase activity, transferring glycosyl groups
EYC51_13665	COG1132	(ABC) transporter
EYC51_13675	COG1530	ribonuclease E activity
EYC51_13720	COG2186	Transcriptional regulator
EYC51_13725	COG0277	FAD linked oxidase domain protein
EYC51_13730	COG0277	FAD linked oxidase domain protein
EYC51_13735	COG0247	lactate metabolic process
EYC51_13740	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_13750	COG4191	Histidine kinase
EYC51_13770	COG2985	domain, Protein
EYC51_13775	COG0076	glutamate decarboxylase activity
EYC51_13795	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYC51_13805	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EYC51_13815	COG0697	spore germination
EYC51_13835	COG3094	Invasion gene expression up-regulator, SirB
EYC51_13845	COG0640	Transcriptional regulator
EYC51_13860	COG0789	Transcriptional regulator
EYC51_13870	COG0659	secondary active sulfate transmembrane transporter activity
EYC51_13875	COG2314	TM2 domain
EYC51_13880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYC51_13885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYC51_13890	COG0791	NLP P60 protein
EYC51_13910	COG1360	Flagellar Motor Protein
EYC51_13920	COG0835	chemotaxis
EYC51_13925	COG0840	transmembrane signaling receptor activity
EYC51_13930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYC51_13940	COG0745	RESPONSE REGULATOR receiver
EYC51_13945	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EYC51_13955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC51_13970	COG2747	anti-sigma28 factor FlgM
EYC51_13980	COG1815	bacterial-type flagellum-dependent cell motility
EYC51_13985	COG1558	bacterial-type flagellum-dependent cell motility
EYC51_13990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYC51_13995	COG1749	Flagellar hook protein flgE
EYC51_14005	COG4786	Flagellar basal body rod
EYC51_14015	COG1706	bacterial-type flagellum-dependent cell motility
EYC51_14025	COG1256	bacterial-type flagellum assembly
EYC51_14030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYC51_14035	COG0840	transmembrane signaling receptor activity
EYC51_14045	COG0840	transmembrane signaling receptor activity
EYC51_14065	COG1987	bacterial-type flagellum assembly
EYC51_14105	COG1157	protein secretion by the type III secretion system
EYC51_14115	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYC51_14120	COG1766	The M ring may be actively involved in energy transduction
EYC51_14125	COG1677	Flagellar hook-basal body complex protein FliE
EYC51_14130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYC51_14155	COG1334	flagellar protein FlaG
EYC51_14160	COG1191	sigma factor activity
EYC51_14220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC51_14240	COG2733	membrane
EYC51_14245	COG0840	transmembrane signaling receptor activity
EYC51_14250	COG0840	transmembrane signaling receptor activity
EYC51_14265	COG3181	Tripartite tricarboxylate transporter family receptor
EYC51_14275	COG2610	gluconate transmembrane transporter activity
EYC51_14285	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_14295	COG2824	Alkylphosphonate utilization operon protein PhnA
EYC51_14310	COG4771	TonB-dependent receptor
EYC51_14315	COG1858	cytochrome C peroxidase
EYC51_14325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYC51_14335	COG1113	amino acid transport
EYC51_14350	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYC51_14375	COG1278	Cold shock
EYC51_14380	COG0642	Histidine kinase
EYC51_14385	COG0745	RESPONSE REGULATOR receiver
EYC51_14400	COG2863	cytochrome
EYC51_14405	COG3258	Cytochrome c
EYC51_14415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYC51_14440	COG0025	NhaP-type Na H and K H
EYC51_14455	COG1289	transmembrane transporter activity
EYC51_14460	COG2252	PERMEase
EYC51_14465	COG0560	Phosphoserine phosphatase
EYC51_14480	COG1999	signal sequence binding
EYC51_14490	COG0069	glutamate synthase activity
EYC51_14500	COG1846	Transcriptional regulator
EYC51_14510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYC51_14550	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_14560	COG1012	belongs to the aldehyde dehydrogenase family
EYC51_14565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC51_14570	COG3264	Mechanosensitive ion channel
EYC51_14570	COG1511	domain protein
EYC51_14575	COG3264	Mechanosensitive ion channel
EYC51_14575	COG1511	domain protein
EYC51_14595	COG1396	sequence-specific DNA binding
EYC51_14600	COG3437	response regulator, receiver
EYC51_14605	COG2205	protein histidine kinase activity
EYC51_14605	COG2198	Histidine kinase
EYC51_14605	COG0784	Response regulator, receiver
EYC51_14610	COG2239	Acts as a magnesium transporter
EYC51_14625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EYC51_14630	COG1490	D-aminoacyl-tRNA deacylase activity
EYC51_14635	COG2076	Multidrug Resistance protein
EYC51_14645	COG0456	acetyltransferase
EYC51_14655	COG0501	Belongs to the peptidase M48B family
EYC51_14785	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EYC51_14815	COG0740	serine-type endopeptidase activity
EYC51_14850	COG4386	tail sheath protein
EYC51_14890	COG3299	homolog of phage Mu protein gp47
EYC51_14910	COG0582	viral genome integration into host DNA
EYC51_14925	COG3179	chitinase
EYC51_14935	COG2135	peptidase activity
EYC51_14995	COG2199	diguanylate cyclase activity
EYC51_15010	COG1522	sequence-specific DNA binding
EYC51_15015	COG0626	cystathionine gamma-synthase activity
EYC51_15025	COG0494	nUDIX hydrolase
EYC51_15030	COG2832	Protein of unknown function (DUF454)
EYC51_15040	COG0137	argininosuccinate synthase activity
EYC51_15045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EYC51_15050	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYC51_15070	COG1609	Transcriptional regulator
EYC51_15085	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYC51_15095	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYC51_15100	COG2205	protein histidine kinase activity
EYC51_15105	COG0745	RESPONSE REGULATOR receiver
EYC51_15110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYC51_15120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC51_15125	COG0268	Binds directly to 16S ribosomal RNA
EYC51_15130	COG0728	peptidoglycan biosynthetic process
EYC51_15140	COG0563	adenylate kinase activity
EYC51_15145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EYC51_15155	COG1663	tetraacyldisaccharide 4'-kinase activity
EYC51_15160	COG0848	biopolymer transport protein
EYC51_15165	COG0811	peptide transport
EYC51_15170	COG1570	exodeoxyribonuclease VII activity
EYC51_15175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYC51_15185	COG0183	Belongs to the thiolase family
EYC51_15195	COG1278	Cold shock
EYC51_15200	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYC51_15205	COG0542	response to heat
EYC51_15210	COG2995	paraquat-inducible protein a
EYC51_15215	COG3008	intermembrane lipid transfer
EYC51_15235	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_15245	COG0411	ABC transporter
EYC51_15270	COG3706	GGDEF domain
EYC51_15270	COG5001	Diguanylate cyclase
EYC51_15270	COG4251	negative regulation of phosphorylation
EYC51_15270	COG2203	Gaf domain
EYC51_15275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EYC51_15280	COG0756	dUTP diphosphatase activity
EYC51_15290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYC51_15295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYC51_15300	COG0196	riboflavin kinase activity
EYC51_15305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYC51_15310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYC51_15310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYC51_15320	COG0210	DNA helicase
EYC51_15345	COG0488	(ABC) transporter
EYC51_15350	COG2890	protein-(glutamine-N5) methyltransferase activity
EYC51_15355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYC51_15360	COG2171	N-acyltransferase activity
EYC51_15375	COG0471	metal ion transport
EYC51_15375	COG3273	potassium ion transport
EYC51_15425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYC51_15430	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYC51_15435	COG0740	serine-type endopeptidase activity
EYC51_15440	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYC51_15445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYC51_15450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYC51_15465	COG0556	nucleotide-excision repair
EYC51_15470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYC51_15475	COG1959	2 iron, 2 sulfur cluster binding
EYC51_15480	COG1104	cysteine desulfurase activity
EYC51_15490	COG0316	Belongs to the HesB IscA family
EYC51_15500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYC51_15505	COG4221	oxidoreductase activity
EYC51_15520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYC51_15525	COG0697	spore germination
EYC51_15530	COG0385	Bile acid
EYC51_15540	COG2831	hemolysin activation secretion protein
EYC51_15570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYC51_15585	COG1136	(ABC) transporter
EYC51_15590	COG0084	hydrolase, TatD family'
EYC51_15605	COG0613	PHP domain protein
EYC51_15615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYC51_15615	COG0047	phosphoribosylformylglycinamidine synthase activity
EYC51_15630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYC51_15630	COG0519	Catalyzes the synthesis of GMP from XMP
EYC51_15635	COG0582	viral genome integration into host DNA
EYC51_15795	COG1484	DNA-dependent DNA replication
EYC51_16040	COG3344	reverse transcriptase
EYC51_16050	COG3344	reverse transcriptase
EYC51_16055	COG0583	DNA-binding transcription factor activity
EYC51_16070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYC51_16085	COG1960	acyl-CoA dehydrogenase activity
EYC51_16090	COG0523	cobalamin synthesis protein
EYC51_16095	COG1469	GTP cyclohydrolase I activity
EYC51_16100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYC51_16110	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYC51_16115	COG0735	belongs to the Fur family
EYC51_16120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYC51_16135	COG3852	Histidine kinase
EYC51_16140	COG0745	RESPONSE REGULATOR receiver
EYC51_16150	COG1017	nitric oxide dioxygenase activity
EYC51_16170	COG0583	DNA-binding transcription factor activity
EYC51_16175	COG2372	response to copper ion
EYC51_16175	COG1276	copper resistance
EYC51_16190	COG0740	serine-type endopeptidase activity
EYC51_16200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYC51_16205	COG0640	Transcriptional regulator
EYC51_16235	COG3485	protocatechuate 3,4-dioxygenase
EYC51_16245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYC51_16250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EYC51_16260	COG3135	benzoate transporter
EYC51_16265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYC51_16270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYC51_16280	COG4555	ABC transporter
EYC51_16290	COG2197	response regulator
EYC51_16320	COG1846	Transcriptional regulator
EYC51_16325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYC51_16330	COG2271	Major facilitator Superfamily
EYC51_16340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYC51_16350	COG0697	spore germination
EYC51_16375	COG3842	ATPase activity
EYC51_16390	COG0642	Histidine kinase
EYC51_16405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYC51_16410	COG0667	Aldo Keto reductase
EYC51_16425	COG0582	viral genome integration into host DNA
EYC51_16430	COG1278	Cold shock
EYC51_16440	COG1272	protein, Hemolysin III
EYC51_16445	COG3422	double-strand break repair
EYC51_16455	COG0477	Major facilitator Superfamily
EYC51_16460	COG0154	amidase activity
EYC51_16475	COG3040	lipid binding
EYC51_16490	COG0765	amino acid transport
EYC51_16495	COG1126	abc transporter atp-binding protein
EYC51_16540	COG2871	sodium ion transport
EYC51_16580	COG2814	Major facilitator Superfamily
EYC51_16585	COG1280	lysine exporter protein (LysE YggA)
EYC51_16615	COG0330	HflC and HflK could
EYC51_16625	COG2226	methyltransferase
EYC51_16635	COG3042	response to heat
EYC51_16645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYC51_16660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYC51_16665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYC51_16670	COG0189	ligase activity
EYC51_16680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYC51_16685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYC51_16715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYC51_16720	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYC51_16725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYC51_16730	COG0072	phenylalanine-tRNA ligase activity
EYC51_16730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYC51_16735	COG0776	regulation of translation
EYC51_16745	COG2833	Protein of unknown function (DUF455)
EYC51_16755	COG5265	(ABC) transporter
EYC51_16760	COG1959	2 iron, 2 sulfur cluster binding
EYC51_16765	COG0719	Fe-S assembly protein
EYC51_16770	COG0396	ATPase activity
EYC51_16775	COG0719	Fe-S assembly protein
EYC51_16785	COG0822	iron-sulfur transferase activity
EYC51_16790	COG2151	metal-sulfur cluster biosynthetic enzyme
EYC51_16805	COG1462	curli production assembly transport component CsgG
EYC51_16825	COG1215	transferase activity, transferring glycosyl groups
EYC51_16830	COG1649	PFAM Uncharacterised BCR, COG1649
EYC51_16830	COG0726	polysaccharide deacetylase
EYC51_16835	COG0457	Tetratricopeptide repeat
EYC51_16935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYC51_17005	COG5410	chromosome segregation
EYC51_17080	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYC51_17085	COG3657	addiction module killer protein
EYC51_17190	COG3949	Membrane
EYC51_17205	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EYC51_17220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYC51_17225	COG0569	domain protein
EYC51_17230	COG1902	pentaerythritol trinitrate reductase activity
EYC51_17240	COG1610	YqeY-like protein
EYC51_17245	COG0587	DNA-directed DNA polymerase activity
EYC51_17285	COG0583	DNA-binding transcription factor activity
EYC51_17290	COG1686	Belongs to the peptidase S11 family
EYC51_17305	COG1360	Flagellar Motor Protein
EYC51_17315	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_17325	COG4221	oxidoreductase activity
EYC51_17330	COG0307	riboflavin synthase, alpha
EYC51_17345	COG1301	dicarboxylic acid transport
EYC51_17350	COG4191	Histidine kinase
EYC51_17395	COG2233	PERMEase
EYC51_17415	COG1846	Transcriptional regulator
EYC51_17420	COG2816	NAD+ diphosphatase activity
EYC51_17425	COG1561	YicC-like family, N-terminal region
EYC51_17440	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYC51_17445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYC51_17450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYC51_17460	COG2153	protein acetylation
EYC51_17465	COG3842	ATPase activity
EYC51_17470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYC51_17475	COG1840	ABC-type Fe3 transport system, periplasmic component
EYC51_17490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYC51_17505	COG0783	Belongs to the Dps family
EYC51_17515	COG3842	ATPase activity
EYC51_17520	COG0395	ABC-type sugar transport system, permease component
EYC51_17525	COG1175	transmembrane transport
EYC51_17530	COG1653	transport
EYC51_17545	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYC51_17565	COG0625	glutathione transferase activity
EYC51_17575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYC51_17580	COG1028	Short-chain dehydrogenase reductase Sdr
EYC51_17585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYC51_17590	COG0114	fumarate hydratase activity
EYC51_17595	COG2133	pyrroloquinoline quinone binding
EYC51_17600	COG0589	response to stress
EYC51_17610	COG2807	transmembrane transport
EYC51_17620	COG0583	DNA-binding transcription factor activity
EYC51_17640	COG4974	Belongs to the 'phage' integrase family
EYC51_17815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYC51_17860	COG0840	transmembrane signaling receptor activity
EYC51_17890	COG0697	spore germination
EYC51_17900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYC51_17920	COG3316	Transposase and inactivated derivatives
EYC51_17990	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYC51_17995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYC51_18015	COG2003	Belongs to the UPF0758 family
EYC51_18125	COG2894	cell division