locus-tag	class	description
MXF72_00005	COG3706	GGDEF domain
MXF72_00010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MXF72_00020	COG0436	Aminotransferase
MXF72_00025	COG0445	tRNA wobble uridine modification
MXF72_00030	COG0357	Ribosomal RNA small subunit methyltransferase G
MXF72_00035	COG1192	Involved in chromosome partitioning
MXF72_00040	COG1475	DNA binding
MXF72_00065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MXF72_00090	COG0081	regulation of translation
MXF72_00095	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MXF72_00100	COG0222	ribosome binding
MXF72_00105	COG0085	RNA polymerase activity
MXF72_00110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MXF72_00115	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
MXF72_00145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MXF72_00150	COG0049	tRNA binding
MXF72_00155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MXF72_00160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MXF72_00165	COG0051	transcription antitermination factor activity, RNA binding
MXF72_00170	COG4176	ABC-type proline glycine betaine transport system permease component
MXF72_00175	COG4175	Glycine betaine
MXF72_00180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MXF72_00185	COG0088	Forms part of the polypeptide exit tunnel
MXF72_00190	COG0089	rRNA binding
MXF72_00195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MXF72_00200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MXF72_00205	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MXF72_00210	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MXF72_00215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MXF72_00220	COG0255	Belongs to the universal ribosomal protein uL29 family
MXF72_00225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MXF72_00240	COG1960	acyl-CoA dehydrogenase activity
MXF72_00245	COG1116	anion transmembrane transporter activity
MXF72_00260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MXF72_00260	COG1648	precorrin-2 dehydrogenase activity
MXF72_00265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MXF72_00270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MXF72_00275	COG0318	PFAM AMP-dependent synthetase and ligase
MXF72_00290	COG2067	long-chain fatty acid transport protein
MXF72_00300	COG0183	Belongs to the thiolase family
MXF72_00305	COG1960	acyl-CoA dehydrogenase activity
MXF72_00320	COG1538	Outer membrane efflux protein
MXF72_00360	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MXF72_00365	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MXF72_00370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MXF72_00375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MXF72_00380	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MXF72_00385	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MXF72_00390	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MXF72_00395	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MXF72_00400	COG1841	ribosomal large subunit assembly
MXF72_00405	COG0200	Binds to the 23S rRNA
MXF72_00410	COG0201	protein transport
MXF72_00420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MXF72_00425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MXF72_00430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MXF72_00435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MXF72_00440	COG0202	RNA polymerase activity
MXF72_00445	COG0203	ribosomal protein L17
MXF72_00450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MXF72_00470	COG4232	protein-disulfide reductase activity
MXF72_00475	COG0113	porphobilinogen synthase activity
MXF72_00480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MXF72_00490	COG1333	cytochrome c biogenesis protein
MXF72_00495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MXF72_00500	COG5001	Diguanylate cyclase
MXF72_00500	COG5002	protein histidine kinase activity
MXF72_00520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MXF72_00525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MXF72_00530	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MXF72_00540	COG2814	Major facilitator Superfamily
MXF72_00555	COG3712	iron ion homeostasis
MXF72_00560	COG1595	DNA-templated transcription, initiation
MXF72_00565	COG2186	Transcriptional regulator
MXF72_00570	COG0179	Fumarylacetoacetate (FAA) hydrolase
MXF72_00575	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_00580	COG0251	oxidation-reduction process
MXF72_00585	COG2814	Major facilitator Superfamily
MXF72_00600	COG2814	Major facilitator Superfamily
MXF72_00605	COG1309	transcriptional regulator
MXF72_00610	COG1802	Transcriptional regulator
MXF72_00620	COG3069	C4-dicarboxylate transmembrane transporter activity
MXF72_00670	COG2423	ornithine cyclodeaminase activity
MXF72_00690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MXF72_00695	COG2365	Tyrosine phosphatase family
MXF72_00725	COG0789	Transcriptional regulator
MXF72_00735	COG0583	DNA-binding transcription factor activity
MXF72_00760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MXF72_00765	COG2986	histidine ammonia-lyase
MXF72_00785	COG1228	amidohydrolase
MXF72_00795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MXF72_00820	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MXF72_00825	COG3568	Endonuclease Exonuclease Phosphatase
MXF72_00845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MXF72_00865	COG0109	protoheme IX farnesyltransferase activity
MXF72_00905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MXF72_00925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MXF72_00935	COG1522	sequence-specific DNA binding
MXF72_00945	COG1595	DNA-templated transcription, initiation
MXF72_00985	COG0583	DNA-binding transcription factor activity
MXF72_00990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MXF72_00995	COG3284	Transcriptional regulator
MXF72_01005	COG2823	Periplasmic or secreted lipoprotein
MXF72_01025	COG1335	isochorismatase
MXF72_01030	COG1335	isochorismatase
MXF72_01040	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_01045	COG0477	Major facilitator Superfamily
MXF72_01050	COG0583	DNA-binding transcription factor activity
MXF72_01055	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MXF72_01070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MXF72_01080	COG2226	methyltransferase
MXF72_01085	COG3706	GGDEF domain
MXF72_01090	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MXF72_01100	COG0656	L-ascorbic acid biosynthetic process
MXF72_01105	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MXF72_01125	COG3483	tryptophan 2,3-dioxygenase activity
MXF72_01135	COG1522	sequence-specific DNA binding
MXF72_01140	COG1802	Transcriptional regulator
MXF72_01145	COG0129	dihydroxy-acid dehydratase activity
MXF72_01150	COG2084	Dehydrogenase
MXF72_01160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MXF72_01165	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MXF72_01185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MXF72_01200	COG4150	thiosulfate binding
MXF72_01205	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MXF72_01210	COG4208	sulfate ABC transporter
MXF72_01215	COG2969	positive regulation of protein catabolic process
MXF72_01220	COG0625	glutathione transferase activity
MXF72_01225	COG2857	Cytochrome c1
MXF72_01230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MXF72_01235	COG0723	plastoquinol--plastocyanin reductase activity
MXF72_01240	COG1970	mechanosensitive ion channel activity
MXF72_01250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MXF72_01260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MXF72_01265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MXF72_01270	COG0537	adenosine 5'-monophosphoramidase activity
MXF72_01275	COG0140	phosphoribosyl-ATP diphosphatase activity
MXF72_01285	COG0107	imidazoleglycerol-phosphate synthase activity
MXF72_01290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MXF72_01300	COG0131	Imidazoleglycerol-phosphate dehydratase
MXF72_01305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MXF72_01315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MXF72_01325	COG0842	Transport permease protein
MXF72_01330	COG1131	(ABC) transporter
MXF72_01345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MXF72_01350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MXF72_01355	COG1127	ABC transporter
MXF72_01370	COG1250	3-hydroxyacyl-CoA dehydrogenase
MXF72_01370	COG1024	Enoyl-CoA hydratase
MXF72_01375	COG0183	Belongs to the thiolase family
MXF72_01470	COG2885	chlorophyll binding
MXF72_01490	COG0697	spore germination
MXF72_01495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MXF72_01500	COG0697	spore germination
MXF72_01505	COG2233	PERMEase
MXF72_01510	COG0604	alcohol dehydrogenase
MXF72_01510	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_01510	COG3321	synthase
MXF72_01515	COG0156	8-amino-7-oxononanoate synthase activity
MXF72_01550	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MXF72_01585	COG1215	transferase activity, transferring glycosyl groups
MXF72_01600	COG0166	Belongs to the GPI family
MXF72_01615	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MXF72_01630	COG4263	nitrous-oxide reductase activity
MXF72_01635	COG0348	domain, Protein
MXF72_01635	COG3901	Regulator of nitric oxide reductase transcription
MXF72_01640	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
MXF72_01645	COG0709	Synthesizes selenophosphate from selenide and ATP
MXF72_01655	COG4771	TonB-dependent receptor
MXF72_01680	COG3276	selenocysteine insertion sequence binding
MXF72_01685	COG1921	L-seryl-tRNASec selenium transferase activity
MXF72_01695	COG2864	formate dehydrogenase
MXF72_01700	COG0437	4 iron, 4 sulfur cluster binding
MXF72_01730	COG1116	anion transmembrane transporter activity
MXF72_01750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MXF72_01755	COG0477	Major facilitator Superfamily
MXF72_01770	COG5002	protein histidine kinase activity
MXF72_01790	COG3180	Ammonia monooxygenase
MXF72_01815	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MXF72_01840	COG2264	protein methyltransferase activity
MXF72_01845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MXF72_01860	COG0811	peptide transport
MXF72_01890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MXF72_01930	COG3550	peptidyl-serine autophosphorylation
MXF72_01940	COG0515	serine threonine protein kinase
MXF72_01940	COG0457	Tetratricopeptide repeat
MXF72_01970	COG2890	protein-(glutamine-N5) methyltransferase activity
MXF72_01975	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MXF72_01980	COG0163	prenyltransferase activity
MXF72_01985	COG0037	tRNA processing
MXF72_02000	COG1024	Enoyl-CoA hydratase
MXF72_02010	COG0356	it plays a direct role in the translocation of protons across the membrane
MXF72_02025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MXF72_02030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MXF72_02035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MXF72_02045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MXF72_02075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MXF72_02120	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MXF72_02135	COG3473	Maleate cis-trans isomerase
MXF72_02140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MXF72_02150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MXF72_02170	COG2204	response regulator
MXF72_02180	COG2205	protein histidine kinase activity
MXF72_02185	COG0745	RESPONSE REGULATOR receiver
MXF72_02190	COG4771	TonB-dependent receptor
MXF72_02195	COG2226	methyltransferase
MXF72_02200	COG1040	competence protein
MXF72_02205	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MXF72_02210	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_02215	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MXF72_02220	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MXF72_02230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MXF72_02235	COG0588	phosphoglycerate mutase activity
MXF72_02245	COG0793	Belongs to the peptidase S41A family
MXF72_02250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MXF72_02270	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MXF72_02285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MXF72_02290	COG0792	nuclease activity
MXF72_02295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MXF72_02300	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MXF72_02305	COG1660	Displays ATPase and GTPase activities
MXF72_02310	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MXF72_02315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MXF72_02325	COG1137	ATPase activity
MXF72_02340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MXF72_02355	COG1271	oxidase subunit
MXF72_02360	COG1294	oxidase, subunit
MXF72_02370	COG4988	ABC transporter
MXF72_02375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MXF72_02405	COG1238	metal cluster binding
MXF72_02410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MXF72_02415	COG1984	allophanate hydrolase subunit 2
MXF72_02420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MXF72_02435	COG0745	RESPONSE REGULATOR receiver
MXF72_02440	COG2226	methyltransferase
MXF72_02455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MXF72_02465	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MXF72_02470	COG1538	Outer membrane efflux protein
MXF72_02475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MXF72_02480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MXF72_02485	COG0351	phosphomethylpyrimidine kinase
MXF72_02490	COG2022	thiamine diphosphate biosynthetic process
MXF72_02505	COG0598	Magnesium transport protein CorA
MXF72_02525	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MXF72_02540	COG1595	DNA-templated transcription, initiation
MXF72_02555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MXF72_02560	COG4206	TonB-dependent receptor
MXF72_02590	COG0477	Major facilitator Superfamily
MXF72_02600	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MXF72_02605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MXF72_02620	COG0237	dephospho-CoA kinase activity
MXF72_02625	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MXF72_02650	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MXF72_02655	COG0494	nUDIX hydrolase
MXF72_02665	COG0142	geranyltranstransferase activity
MXF72_02670	COG0786	glutamate:sodium symporter activity
MXF72_02685	COG3604	Transcriptional regulator
MXF72_02710	COG3384	dioxygenase
MXF72_02715	COG2259	Doxx family
MXF72_02720	COG0583	DNA-binding transcription factor activity
MXF72_02725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MXF72_02730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MXF72_02735	COG0154	amidase activity
MXF72_02740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MXF72_02745	COG1077	Cell shape determining protein MreB Mrl
MXF72_02750	COG1792	Involved in formation and maintenance of cell shape
MXF72_02760	COG0768	penicillin binding
MXF72_02765	COG0772	Belongs to the SEDS family
MXF72_02775	COG2177	Part of the ABC transporter FtsEX involved in
MXF72_02780	COG2884	Cell division ATP-binding protein ftsE
MXF72_02785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_02790	COG4597	amino acid ABC transporter
MXF72_02795	COG0765	amino acid transport
MXF72_02800	COG1126	abc transporter atp-binding protein
MXF72_02815	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MXF72_02840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MXF72_02845	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MXF72_02850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MXF72_02855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MXF72_02860	COG3237	CsbD-like
MXF72_02870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MXF72_02885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MXF72_02890	COG0352	thiamine-phosphate diphosphorylase activity
MXF72_02905	COG1678	Uncharacterized ACR, COG1678
MXF72_02920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MXF72_02930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MXF72_02935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MXF72_02950	COG3150	esterase
MXF72_02955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MXF72_02965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MXF72_02970	COG0511	ligase activity, forming carbon-carbon bonds
MXF72_02975	COG0439	Biotin carboxylase
MXF72_02990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MXF72_02995	COG3133	Outer membrane lipoprotein
MXF72_03000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MXF72_03000	COG2169	Transcriptional regulator
MXF72_03005	COG0762	integral membrane protein
MXF72_03035	COG0583	DNA-binding transcription factor activity
MXF72_03045	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_03055	COG0596	Alpha beta hydrolase
MXF72_03055	COG2945	thiolester hydrolase activity
MXF72_03060	COG2233	PERMEase
MXF72_03065	COG0402	S-adenosylhomocysteine deaminase activity
MXF72_03070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MXF72_03075	COG4566	intracellular signal transduction
MXF72_03080	COG0745	RESPONSE REGULATOR receiver
MXF72_03080	COG2205	protein histidine kinase activity
MXF72_03080	COG4191	Histidine kinase
MXF72_03105	COG3028	Belongs to the UPF0307 family
MXF72_03110	COG0312	modulator of DNA gyrase
MXF72_03115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MXF72_03120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MXF72_03125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MXF72_03130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MXF72_03140	COG0316	Belongs to the HesB IscA family
MXF72_03145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MXF72_03150	COG0739	heme binding
MXF72_03155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MXF72_03160	COG1881	PFAM PEBP family protein
MXF72_03165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MXF72_03170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MXF72_03175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MXF72_03175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MXF72_03230	COG4977	sequence-specific DNA binding
MXF72_03240	COG0642	Histidine kinase
MXF72_03245	COG0745	RESPONSE REGULATOR receiver
MXF72_03250	COG0431	NADPH-dependent FMN reductase
MXF72_03255	COG1393	Belongs to the ArsC family
MXF72_03270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_03280	COG1280	lysine exporter protein (LysE YggA)
MXF72_03295	COG0583	DNA-binding transcription factor activity
MXF72_03305	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MXF72_03315	COG1454	alcohol dehydrogenase
MXF72_03320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MXF72_03325	COG0583	DNA-binding transcription factor activity
MXF72_03345	COG0583	DNA-binding transcription factor activity
MXF72_03350	COG0604	alcohol dehydrogenase
MXF72_03365	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MXF72_03385	COG1024	Enoyl-CoA hydratase
MXF72_03395	COG0604	alcohol dehydrogenase
MXF72_03430	COG1877	trehalose-phosphatase activity
MXF72_03435	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_03450	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MXF72_03470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MXF72_03495	COG1054	Belongs to the UPF0176 family
MXF72_03505	COG1301	dicarboxylic acid transport
MXF72_03510	COG4191	Histidine kinase
MXF72_03515	COG2204	response regulator
MXF72_03525	COG1388	LysM domain
MXF72_03525	COG0741	lytic transglycosylase activity
MXF72_03530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MXF72_03535	COG2226	methyltransferase
MXF72_03540	COG0328	RNA-DNA hybrid ribonuclease activity
MXF72_03545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MXF72_03550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MXF72_03565	COG2031	fatty acid transporter
MXF72_03570	COG4206	TonB-dependent receptor
MXF72_03580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MXF72_03585	COG1120	ATPase activity
MXF72_03600	COG0596	Alpha beta hydrolase
MXF72_03605	COG2309	aminopeptidase activity
MXF72_03610	COG1335	isochorismatase
MXF72_03635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MXF72_03660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MXF72_03665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MXF72_03675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_03680	COG3608	succinylglutamate desuccinylase aspartoacylase
MXF72_03680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MXF72_03685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MXF72_03685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MXF72_03695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MXF72_03705	COG2188	Transcriptional regulator
MXF72_03710	COG1234	tRNA 3'-trailer cleavage
MXF72_03725	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_03740	COG3706	GGDEF domain
MXF72_03765	COG0411	ABC transporter
MXF72_03770	COG0410	ABC transporter
MXF72_03780	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MXF72_03780	COG2010	Cytochrome c
MXF72_03785	COG2080	2 iron, 2 sulfur cluster binding
MXF72_03790	COG2010	Cytochrome c
MXF72_03790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MXF72_03795	COG0596	Alpha beta hydrolase
MXF72_03800	COG2309	aminopeptidase activity
MXF72_03805	COG1335	isochorismatase
MXF72_03820	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
MXF72_03850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MXF72_03855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MXF72_03860	COG0742	ribosomal rna small subunit methyltransferase
MXF72_03885	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MXF72_03890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MXF72_03900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MXF72_03910	COG1414	Transcriptional regulator
MXF72_03925	COG0284	orotidine-5'-phosphate decarboxylase activity
MXF72_03930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MXF72_03940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MXF72_03955	COG0154	amidase activity
MXF72_03960	COG3706	GGDEF domain
MXF72_03970	COG1741	Belongs to the pirin family
MXF72_03975	COG0583	DNA-binding transcription factor activity
MXF72_03990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MXF72_03995	COG2895	sulfate adenylyltransferase (ATP) activity
MXF72_04005	COG0175	sulfate reduction
MXF72_04010	COG0697	spore germination
MXF72_04025	COG3634	alkyl hydroperoxide reductase activity
MXF72_04030	COG0583	DNA-binding transcription factor activity
MXF72_04035	COG0427	acetyl-CoA hydrolase
MXF72_04055	COG3845	ABC transporter
MXF72_04060	COG4603	Belongs to the binding-protein-dependent transport system permease family
MXF72_04065	COG1079	Belongs to the binding-protein-dependent transport system permease family
MXF72_04090	COG0596	Alpha beta hydrolase
MXF72_04105	COG0823	Involved in the tonB-independent uptake of proteins
MXF72_04120	COG0811	peptide transport
MXF72_04125	COG0824	Thioesterase
MXF72_04130	COG0442	prolyl-tRNA aminoacylation
MXF72_04135	COG0494	nUDIX hydrolase
MXF72_04150	COG2084	Dehydrogenase
MXF72_04155	COG1840	ABC-type Fe3 transport system, periplasmic component
MXF72_04160	COG3842	ATPase activity
MXF72_04165	COG1177	transmembrane transport
MXF72_04205	COG4654	Cytochrome c, class I
MXF72_04210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MXF72_04280	COG0415	Belongs to the DNA photolyase family
MXF72_04290	COG0418	dihydroorotase activity
MXF72_04300	COG2255	four-way junction helicase activity
MXF72_04310	COG0632	four-way junction helicase activity
MXF72_04315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MXF72_04325	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MXF72_04335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MXF72_04360	COG0429	hydrolase of the alpha beta-hydrolase fold
MXF72_04380	COG0513	Belongs to the DEAD box helicase family
MXF72_04400	COG1414	Transcriptional regulator
MXF72_04415	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MXF72_04420	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MXF72_04435	COG1846	Transcriptional regulator
MXF72_04440	COG1027	Aspartate ammonia-lyase
MXF72_04455	COG0516	GMP reductase activity
MXF72_04455	COG0517	IMP dehydrogenase activity
MXF72_04520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MXF72_04565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MXF72_04585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MXF72_04590	COG3278	Belongs to the heme-copper respiratory oxidase family
MXF72_04635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MXF72_04650	COG0789	Transcriptional regulator
MXF72_04660	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MXF72_04665	COG0505	Belongs to the CarA family
MXF72_04680	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MXF72_04695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MXF72_04705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MXF72_04710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MXF72_04720	COG3243	poly(R)-hydroxyalkanoic acid synthase
MXF72_04725	COG1538	Outer membrane efflux protein
MXF72_04730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MXF72_04735	COG0842	Transport permease protein
MXF72_04735	COG1129	ABC transporter
MXF72_04740	COG0842	Transport permease protein
MXF72_04750	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_04785	COG2814	Major facilitator Superfamily
MXF72_04790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MXF72_04795	COG0154	amidase activity
MXF72_04815	COG2197	response regulator
MXF72_04820	COG2205	protein histidine kinase activity
MXF72_04820	COG0784	Response regulator, receiver
MXF72_04825	COG0784	Response regulator, receiver
MXF72_04825	COG2205	protein histidine kinase activity
MXF72_04835	COG3121	Chaperone
MXF72_04855	COG2814	Major facilitator Superfamily
MXF72_04865	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MXF72_04870	COG3971	2-oxopent-4-enoate hydratase activity
MXF72_04885	COG0446	pyridine nucleotide-disulphide oxidoreductase
MXF72_04900	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MXF72_04905	COG4638	Rieske (2fe-2S)
MXF72_04910	COG0583	DNA-binding transcription factor activity
MXF72_04920	COG0513	Belongs to the DEAD box helicase family
MXF72_04955	COG1414	Transcriptional regulator
MXF72_04990	COG1454	alcohol dehydrogenase
MXF72_05005	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MXF72_05010	COG2819	hydrolase of the alpha beta superfamily
MXF72_05020	COG2814	Major facilitator Superfamily
MXF72_05040	COG2814	Major facilitator Superfamily
MXF72_05065	COG1538	Outer membrane efflux protein
MXF72_05090	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MXF72_05100	COG1301	dicarboxylic acid transport
MXF72_05105	COG0477	Major facilitator Superfamily
MXF72_05115	COG2267	carboxylic ester hydrolase activity
MXF72_05135	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MXF72_05140	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MXF72_05145	COG0735	belongs to the Fur family
MXF72_05150	COG0497	DNA recombination
MXF72_05160	COG1420	regulation of RNA biosynthetic process
MXF72_05165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MXF72_05170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MXF72_05175	COG0443	Heat shock 70 kDa protein
MXF72_05180	COG0484	heat shock protein binding
MXF72_05185	COG0612	Peptidase, M16
MXF72_05250	COG4964	Belongs to the GSP D family
MXF72_05290	COG2204	response regulator
MXF72_05310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MXF72_05335	COG1960	acyl-CoA dehydrogenase activity
MXF72_05340	COG2272	Belongs to the type-B carboxylesterase lipase family
MXF72_05360	COG0477	Major facilitator Superfamily
MXF72_05380	COG0492	ferredoxin-NADP+ reductase activity
MXF72_05385	COG1674	ftsk spoiiie
MXF72_05390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MXF72_05395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MXF72_05400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MXF72_05420	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_05425	COG3022	response to hydroperoxide
MXF72_05430	COG1289	transmembrane transporter activity
MXF72_05435	COG0028	Belongs to the TPP enzyme family
MXF72_05440	COG0440	acetolactate synthase activity
MXF72_05445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MXF72_05455	COG1183	phosphatidylcholine synthase activity
MXF72_05460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MXF72_05465	COG1185	polyribonucleotide nucleotidyltransferase activity
MXF72_05485	COG0604	alcohol dehydrogenase
MXF72_05490	COG0149	triose-phosphate isomerase activity
MXF72_05505	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MXF72_05510	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MXF72_05515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MXF72_05520	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MXF72_05525	COG0649	NAD binding
MXF72_05540	COG1034	ATP synthesis coupled electron transport
MXF72_05545	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MXF72_05550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MXF72_05560	COG0713	ATP synthesis coupled electron transport
MXF72_05575	COG1007	ATP synthesis coupled electron transport
MXF72_05585	COG2070	2-Nitropropane dioxygenase
MXF72_05590	COG0560	Phosphoserine phosphatase
MXF72_05595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MXF72_05600	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MXF72_05605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MXF72_05620	COG1214	PFAM Peptidase M22, glycoprotease
MXF72_05625	COG1573	uracil-dna glycosylase
MXF72_05635	COG1196	nuclear chromosome segregation
MXF72_05645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MXF72_05650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MXF72_05660	COG2917	probably involved in intracellular septation
MXF72_05665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MXF72_05690	COG3047	cAMP biosynthetic process
MXF72_05695	COG1129	ABC transporter
MXF72_05700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MXF72_05705	COG2878	Part of a membrane complex involved in electron transport
MXF72_05715	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MXF72_05720	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MXF72_05730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MXF72_05735	COG0133	tryptophan synthase activity
MXF72_05740	COG0159	tryptophan synthase activity
MXF72_05745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MXF72_05750	COG1530	ribonuclease E activity
MXF72_05755	COG0564	pseudouridine synthase activity
MXF72_05760	COG0546	phosphoglycolate phosphatase activity
MXF72_05765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MXF72_05770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MXF72_05775	COG3023	N-Acetylmuramoyl-L-alanine amidase
MXF72_05785	COG0424	maF-like protein
MXF72_05790	COG1399	metal-binding, possibly nucleic acid-binding protein
MXF72_05795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MXF72_05805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MXF72_05810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MXF72_05815	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MXF72_05825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MXF72_05850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MXF72_05865	COG0571	ribonuclease III activity
MXF72_05870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MXF72_05875	COG1381	Involved in DNA repair and RecF pathway recombination
MXF72_05890	COG1045	serine acetyltransferase
MXF72_05905	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MXF72_05915	COG0583	DNA-binding transcription factor activity
MXF72_05925	COG0583	DNA-binding transcription factor activity
MXF72_05935	COG0791	NLP P60 protein
MXF72_05945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MXF72_05980	COG0504	CTP synthase activity
MXF72_05990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MXF72_06005	COG2814	Major facilitator Superfamily
MXF72_06015	COG0148	phosphopyruvate hydratase activity
MXF72_06020	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MXF72_06030	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MXF72_06045	COG1981	membrane
MXF72_06050	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MXF72_06055	COG1466	dna polymerase III delta subunit
MXF72_06065	COG0495	leucyl-tRNA aminoacylation
MXF72_06070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MXF72_06075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MXF72_06080	COG2814	Major facilitator Superfamily
MXF72_06085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MXF72_06095	COG4176	ABC-type proline glycine betaine transport system permease component
MXF72_06100	COG4175	Glycine betaine
MXF72_06105	COG0534	Mate efflux family protein
MXF72_06120	COG2271	Major facilitator Superfamily
MXF72_06130	COG0477	Major facilitator Superfamily
MXF72_06135	COG1737	Transcriptional regulator
MXF72_06140	COG2003	Belongs to the UPF0758 family
MXF72_06145	COG1047	Peptidyl-prolyl cis-trans
MXF72_06150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MXF72_06155	COG0625	glutathione transferase activity
MXF72_06160	COG2084	Dehydrogenase
MXF72_06170	COG0023	Translation Initiation Factor
MXF72_06190	COG0424	maF-like protein
MXF72_06195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MXF72_06200	COG0799	negative regulation of ribosome biogenesis
MXF72_06205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MXF72_06215	COG0151	Belongs to the GarS family
MXF72_06220	COG0217	transcriptional regulatory protein
MXF72_06225	COG0433	COG0433 Predicted ATPase
MXF72_06235	COG0473	3-isopropylmalate dehydrogenase activity
MXF72_06250	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MXF72_06255	COG0308	aminopeptidase N
MXF72_06270	COG0312	modulator of DNA gyrase
MXF72_06280	COG1846	Transcriptional regulator
MXF72_06285	COG0456	acetyltransferase
MXF72_06295	COG0662	Cupin 2, conserved barrel domain protein
MXF72_06300	COG5285	phytanoyl-CoA dioxygenase
MXF72_06315	COG1126	abc transporter atp-binding protein
MXF72_06320	COG0765	amino acid transport
MXF72_06325	COG0765	amino acid transport
MXF72_06330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_06335	COG1966	Carbon starvation protein
MXF72_06340	COG2879	small protein
MXF72_06345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MXF72_06350	COG0277	FAD linked oxidase domain protein
MXF72_06355	COG0482	sulfurtransferase activity
MXF72_06360	COG0730	response to heat
MXF72_06365	COG0657	acetylesterase activity
MXF72_06375	COG0625	glutathione transferase activity
MXF72_06385	COG3909	cytochrome
MXF72_06390	COG0004	ammonium transporteR
MXF72_06395	COG0347	Belongs to the P(II) protein family
MXF72_06400	COG1846	Transcriptional regulator
MXF72_06405	COG2175	clavaminate synthase activity
MXF72_06410	COG2271	Major facilitator Superfamily
MXF72_06420	COG2321	neutral zinc metallopeptidase
MXF72_06425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MXF72_06440	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MXF72_06445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MXF72_06460	COG2119	membrane
MXF72_06465	COG0840	transmembrane signaling receptor activity
MXF72_06480	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MXF72_06485	COG2046	Belongs to the sulfate adenylyltransferase family
MXF72_06490	COG0784	Response regulator, receiver
MXF72_06490	COG2198	Histidine kinase
MXF72_06490	COG2205	protein histidine kinase activity
MXF72_06500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MXF72_06520	COG1280	lysine exporter protein (LysE YggA)
MXF72_06525	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MXF72_06535	COG0625	glutathione transferase activity
MXF72_06585	COG0488	(ABC) transporter
MXF72_06595	COG1309	transcriptional regulator
MXF72_06600	COG0251	oxidation-reduction process
MXF72_06610	COG0436	Aminotransferase
MXF72_06620	COG4335	DNA alkylation repair
MXF72_06625	COG1408	metallophosphoesterase
MXF72_06630	COG0753	catalase activity
MXF72_06650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MXF72_06660	COG0583	DNA-binding transcription factor activity
MXF72_06670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MXF72_06685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MXF72_06695	COG0287	Prephenate dehydrogenase
MXF72_06700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MXF72_06705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MXF72_06725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MXF72_06730	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MXF72_06735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MXF72_06750	COG2951	lytic endotransglycosylase activity
MXF72_06755	COG0123	including yeast histone deacetylase and acetoin utilization protein
MXF72_06770	COG1960	acyl-CoA dehydrogenase activity
MXF72_06775	COG0450	alkyl hydroperoxide reductase
MXF72_06795	COG0335	large ribosomal subunit rRNA binding
MXF72_06805	COG1162	GTPase activity
MXF72_06810	COG0501	Belongs to the peptidase M48B family
MXF72_06815	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MXF72_06820	COG3396	Phenylacetate-CoA oxygenase
MXF72_06825	COG3460	Phenylacetate-CoA oxygenase
MXF72_06830	COG3396	Phenylacetate-CoA oxygenase
MXF72_06835	COG2151	metal-sulfur cluster biosynthetic enzyme
MXF72_06840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MXF72_06845	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_06850	COG1024	Enoyl-CoA hydratase
MXF72_06855	COG2050	protein possibly involved in aromatic compounds catabolism
MXF72_06865	COG0736	holo-[acyl-carrier-protein] synthase activity
MXF72_06870	COG1472	Belongs to the glycosyl hydrolase 3 family
MXF72_06890	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MXF72_06890	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MXF72_06895	COG2224	Isocitrate lyase
MXF72_06900	COG2217	Heavy metal translocating P-type atpase
MXF72_06910	COG3278	Belongs to the heme-copper respiratory oxidase family
MXF72_06930	COG0348	domain, Protein
MXF72_06945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MXF72_06950	COG0542	response to heat
MXF72_06955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MXF72_06960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MXF72_06990	COG0601	transmembrane transport
MXF72_06995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MXF72_07015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MXF72_07020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MXF72_07025	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MXF72_07050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MXF72_07085	COG2351	hydroxyisourate hydrolase activity
MXF72_07100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MXF72_07105	COG0425	Belongs to the sulfur carrier protein TusA family
MXF72_07110	COG0228	four-way junction DNA binding
MXF72_07120	COG0336	Belongs to the RNA methyltransferase TrmD family
MXF72_07125	COG0697	spore germination
MXF72_07130	COG0583	DNA-binding transcription factor activity
MXF72_07140	COG0105	UTP biosynthetic process
MXF72_07145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MXF72_07160	COG0124	histidyl-tRNA synthetase
MXF72_07165	COG2976	Protein conserved in bacteria
MXF72_07170	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MXF72_07175	COG1160	GTP binding
MXF72_07185	COG1923	regulation of RNA biosynthetic process
MXF72_07190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MXF72_07195	COG0330	HflC and HflK could
MXF72_07200	COG0330	HflC and HflK could
MXF72_07210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MXF72_07215	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MXF72_07220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MXF72_07235	COG2205	protein histidine kinase activity
MXF72_07240	COG0745	RESPONSE REGULATOR receiver
MXF72_07250	COG0402	S-adenosylhomocysteine deaminase activity
MXF72_07260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MXF72_07285	COG3135	benzoate transporter
MXF72_07290	COG2207	Transcriptional regulator
MXF72_07295	COG2807	transmembrane transport
MXF72_07300	COG2814	Major facilitator Superfamily
MXF72_07305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MXF72_07315	COG1741	Belongs to the pirin family
MXF72_07325	COG0625	glutathione transferase activity
MXF72_07330	COG3530	Putative quorum-sensing-regulated virulence factor
MXF72_07335	COG0412	Dienelactone hydrolase
MXF72_07355	COG1840	ABC-type Fe3 transport system, periplasmic component
MXF72_07360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MXF72_07370	COG3842	ATPase activity
MXF72_07375	COG0583	DNA-binding transcription factor activity
MXF72_07410	COG2375	cellular response to nickel ion
MXF72_07430	COG1850	ribulose-bisphosphate carboxylase activity
MXF72_07445	COG1126	abc transporter atp-binding protein
MXF72_07450	COG0765	amino acid transport
MXF72_07455	COG0765	amino acid transport
MXF72_07490	COG0557	exoribonuclease II activity
MXF72_07495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MXF72_07500	COG0626	cystathionine gamma-synthase activity
MXF72_07505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MXF72_07510	COG2010	Cytochrome c
MXF72_07520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MXF72_07520	COG1648	precorrin-2 dehydrogenase activity
MXF72_07525	COG0535	radical SAM domain protein
MXF72_07540	COG1522	sequence-specific DNA binding
MXF72_07555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MXF72_07555	COG1648	precorrin-2 dehydrogenase activity
MXF72_07570	COG1278	Cold shock
MXF72_07590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MXF72_07595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MXF72_07600	COG4208	sulfate ABC transporter
MXF72_07605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MXF72_07630	COG0642	Histidine kinase
MXF72_07635	COG3158	transport of potassium into the cell
MXF72_07650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MXF72_07660	COG0477	Major facilitator Superfamily
MXF72_07675	COG2212	antiporter activity
MXF72_07685	COG0651	ATP synthesis coupled electron transport
MXF72_07690	COG1006	Multisubunit Na H antiporter MnhC subunit
MXF72_07695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MXF72_07695	COG2111	Na H antiporter
MXF72_07705	COG2070	2-Nitropropane dioxygenase
MXF72_07720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MXF72_07735	COG0540	Belongs to the ATCase OTCase family
MXF72_07740	COG1301	dicarboxylic acid transport
MXF72_07760	COG2084	Dehydrogenase
MXF72_07765	COG0129	dihydroxy-acid dehydratase activity
MXF72_07785	COG3162	membrane
MXF72_07790	COG1024	Enoyl-CoA hydratase
MXF72_07795	COG0318	PFAM AMP-dependent synthetase and ligase
MXF72_07810	COG0477	Major facilitator Superfamily
MXF72_07825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MXF72_07830	COG2137	regulation of response to DNA damage stimulus
MXF72_07835	COG0583	DNA-binding transcription factor activity
MXF72_07840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MXF72_07850	COG0045	succinate-CoA ligase (ADP-forming) activity
MXF72_07855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MXF72_07860	COG0861	Integral membrane protein TerC family
MXF72_07865	COG0181	hydroxymethylbilane synthase activity
MXF72_07875	COG2959	enzyme of heme biosynthesis
MXF72_07900	COG3712	iron ion homeostasis
MXF72_07905	COG4774	siderophore transport
MXF72_07915	COG1595	DNA-templated transcription, initiation
MXF72_07955	COG4964	Belongs to the GSP D family
MXF72_07985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MXF72_07990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MXF72_08000	COG1295	ribonuclease BN
MXF72_08010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MXF72_08015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MXF72_08025	COG0583	DNA-binding transcription factor activity
MXF72_08040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MXF72_08045	COG0625	glutathione transferase activity
MXF72_08050	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MXF72_08070	COG0473	3-isopropylmalate dehydrogenase activity
MXF72_08075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MXF72_08085	COG0101	tRNA pseudouridine synthase activity
MXF72_08095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_08100	COG0135	phosphoribosylanthranilate isomerase activity
MXF72_08105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MXF72_08120	COG2207	Transcriptional regulator
MXF72_08125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MXF72_08125	COG0519	Catalyzes the synthesis of GMP from XMP
MXF72_08130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MXF72_08135	COG0318	PFAM AMP-dependent synthetase and ligase
MXF72_08140	COG1666	GTP binding
MXF72_08150	COG0842	Transport permease protein
MXF72_08155	COG1131	(ABC) transporter
MXF72_08160	COG0590	tRNA wobble adenosine to inosine editing
MXF72_08165	COG1619	proteins homologs of microcin C7 resistance protein MccF
MXF72_08170	COG0488	(ABC) transporter
MXF72_08190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MXF72_08195	COG2252	PERMEase
MXF72_08200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MXF72_08205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MXF72_08210	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MXF72_08215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MXF72_08225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MXF72_08235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MXF72_08250	COG0165	Argininosuccinate lyase
MXF72_08255	COG0668	transmembrane transport
MXF72_08265	COG0656	L-ascorbic acid biosynthetic process
MXF72_08270	COG2814	Major facilitator Superfamily
MXF72_08275	COG3161	chorismate lyase activity
MXF72_08280	COG1187	pseudouridine synthase activity
MXF72_08285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MXF72_08290	COG0584	glycerophosphoryl diester phosphodiesterase
MXF72_08295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MXF72_08300	COG0739	heme binding
MXF72_08305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MXF72_08325	COG0179	Fumarylacetoacetate (FAA) hydrolase
MXF72_08335	COG0583	DNA-binding transcription factor activity
MXF72_08340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MXF72_08345	COG1758	RNA polymerase activity
MXF72_08350	COG0194	GDP metabolic process
MXF72_08385	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MXF72_08395	COG0183	Belongs to the thiolase family
MXF72_08400	COG0183	Belongs to the thiolase family
MXF72_08420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MXF72_08425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MXF72_08430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MXF72_08440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MXF72_08460	COG0183	Belongs to the thiolase family
MXF72_08480	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_08485	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_08490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MXF72_08495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_08500	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MXF72_08505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_08520	COG0640	Transcriptional regulator
MXF72_08525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MXF72_08535	COG1999	signal sequence binding
MXF72_08545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MXF72_08560	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MXF72_08565	COG0508	dehydrogenase complex catalyzes the overall conversion of
MXF72_08570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MXF72_08575	COG0285	dihydrofolate synthase activity
MXF72_08585	COG1286	toxin biosynthetic process
MXF72_08610	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MXF72_08615	COG0024	Methionine aminopeptidase
MXF72_08620	COG0052	Belongs to the universal ribosomal protein uS2 family
MXF72_08625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MXF72_08630	COG0528	UMP kinase activity
MXF72_08635	COG0233	cytoplasmic translational termination
MXF72_08640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MXF72_08645	COG0575	Belongs to the CDS family
MXF72_08650	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MXF72_08660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MXF72_08670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MXF72_08675	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MXF72_08685	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MXF72_08690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MXF72_08695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MXF72_08720	COG1252	NADH dehydrogenase
MXF72_08725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MXF72_08730	COG2867	negative regulation of translational initiation
MXF72_08735	COG2914	Belongs to the UPF0125 (RnfH) family
MXF72_08740	COG1960	acyl-CoA dehydrogenase activity
MXF72_08760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MXF72_08770	COG0470	DNA polymerase III
MXF72_08775	COG0084	hydrolase, TatD family'
MXF72_08800	COG0625	glutathione transferase activity
MXF72_08805	COG1393	Belongs to the ArsC family
MXF72_08810	COG2353	YceI-like domain
MXF72_08820	COG3038	cytochrome b561
MXF72_08860	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_08875	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MXF72_08880	COG2132	Multicopper oxidase
MXF72_08890	COG4974	Belongs to the 'phage' integrase family
MXF72_08895	COG0583	DNA-binding transcription factor activity
MXF72_08930	COG0583	DNA-binding transcription factor activity
MXF72_08940	COG2807	transmembrane transport
MXF72_08945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MXF72_08950	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_08960	COG0235	Class ii aldolase
MXF72_08965	COG2207	Transcriptional regulator
MXF72_08970	COG4654	Cytochrome c, class I
MXF72_08975	COG0589	response to stress
MXF72_08980	COG2226	methyltransferase
MXF72_08985	COG2133	pyrroloquinoline quinone binding
MXF72_08990	COG0114	fumarate hydratase activity
MXF72_09000	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_09005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MXF72_09015	COG0625	glutathione transferase activity
MXF72_09035	COG0559	Belongs to the binding-protein-dependent transport system permease family
MXF72_09050	COG1653	transport
MXF72_09055	COG1175	transmembrane transport
MXF72_09060	COG0395	ABC-type sugar transport system, permease component
MXF72_09065	COG3842	ATPase activity
MXF72_09075	COG0783	Belongs to the Dps family
MXF72_09085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MXF72_09100	COG1840	ABC-type Fe3 transport system, periplasmic component
MXF72_09105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MXF72_09110	COG3842	ATPase activity
MXF72_09125	COG0583	DNA-binding transcription factor activity
MXF72_09130	COG2153	protein acetylation
MXF72_09135	COG0174	glutamine synthetase
MXF72_09140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MXF72_09145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MXF72_09150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MXF72_09165	COG1561	YicC-like family, N-terminal region
MXF72_09170	COG2816	NAD+ diphosphatase activity
MXF72_09200	COG2814	Major facilitator Superfamily
MXF72_09215	COG1473	amidohydrolase
MXF72_09220	COG2867	negative regulation of translational initiation
MXF72_09220	COG2226	methyltransferase
MXF72_09225	COG0071	Belongs to the small heat shock protein (HSP20) family
MXF72_09230	COG2233	PERMEase
MXF72_09275	COG0307	riboflavin synthase, alpha
MXF72_09280	COG4221	oxidoreductase activity
MXF72_09285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MXF72_09290	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_09300	COG1360	Flagellar Motor Protein
MXF72_09315	COG1686	Belongs to the peptidase S11 family
MXF72_09320	COG0583	DNA-binding transcription factor activity
MXF72_09360	COG0587	DNA-directed DNA polymerase activity
MXF72_09365	COG1610	YqeY-like protein
MXF72_09375	COG1902	pentaerythritol trinitrate reductase activity
MXF72_09380	COG0569	domain protein
MXF72_09385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MXF72_09400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MXF72_09410	COG3949	Membrane
MXF72_09430	COG3258	Cytochrome c
MXF72_09435	COG3048	D-serine ammonia-lyase activity
MXF72_09440	COG2207	Transcriptional regulator
MXF72_09500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MXF72_09510	COG4172	Belongs to the ABC transporter superfamily
MXF72_09515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MXF72_09520	COG0601	transmembrane transport
MXF72_09525	COG0747	negative chemotaxis
MXF72_09555	COG1181	Belongs to the D-alanine--D-alanine ligase family
MXF72_09555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MXF72_09565	COG2274	protein secretion by the type I secretion system
MXF72_09590	COG1538	Outer membrane efflux protein
MXF72_09610	COG2151	metal-sulfur cluster biosynthetic enzyme
MXF72_09615	COG0822	iron-sulfur transferase activity
MXF72_09625	COG0719	Fe-S assembly protein
MXF72_09630	COG0396	ATPase activity
MXF72_09635	COG0719	Fe-S assembly protein
MXF72_09640	COG1959	2 iron, 2 sulfur cluster binding
MXF72_09645	COG5265	(ABC) transporter
MXF72_09660	COG2833	Protein of unknown function (DUF455)
MXF72_09675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MXF72_09675	COG0072	phenylalanine-tRNA ligase activity
MXF72_09680	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MXF72_09685	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MXF72_09690	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MXF72_09720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MXF72_09725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MXF72_09740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MXF72_09745	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MXF72_09760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MXF72_09770	COG3042	response to heat
MXF72_09780	COG2226	methyltransferase
MXF72_09790	COG0330	HflC and HflK could
MXF72_09815	COG0402	S-adenosylhomocysteine deaminase activity
MXF72_09825	COG1609	Transcriptional regulator
MXF72_09830	COG1280	lysine exporter protein (LysE YggA)
MXF72_09835	COG2814	Major facilitator Superfamily
MXF72_09865	COG2871	sodium ion transport
MXF72_09915	COG1126	abc transporter atp-binding protein
MXF72_09920	COG0765	amino acid transport
MXF72_09925	COG0765	amino acid transport
MXF72_09930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_09955	COG3422	double-strand break repair
MXF72_09960	COG1272	protein, Hemolysin III
MXF72_09980	COG0667	Aldo Keto reductase
MXF72_09985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MXF72_09990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MXF72_10015	COG3842	ATPase activity
MXF72_10040	COG0697	spore germination
MXF72_10050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MXF72_10060	COG2271	Major facilitator Superfamily
MXF72_10065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MXF72_10070	COG1846	Transcriptional regulator
MXF72_10095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MXF72_10100	COG2197	response regulator
MXF72_10110	COG4555	ABC transporter
MXF72_10135	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MXF72_10140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MXF72_10145	COG3135	benzoate transporter
MXF72_10155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MXF72_10160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MXF72_10170	COG3485	protocatechuate 3,4-dioxygenase
MXF72_10195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MXF72_10220	COG0640	Transcriptional regulator
MXF72_10250	COG1960	acyl-CoA dehydrogenase activity
MXF72_10260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MXF72_10310	COG0740	serine-type endopeptidase activity
MXF72_10315	COG0625	glutathione transferase activity
MXF72_10320	COG2816	NAD+ diphosphatase activity
MXF72_10345	COG1309	transcriptional regulator
MXF72_10380	COG2070	2-Nitropropane dioxygenase
MXF72_10395	COG1942	4-Oxalocrotonate Tautomerase
MXF72_10405	COG1566	PFAM secretion protein HlyD family protein
MXF72_10415	COG1289	transmembrane transporter activity
MXF72_10420	COG0583	DNA-binding transcription factor activity
MXF72_10425	COG0494	nUDIX hydrolase
MXF72_10440	COG2207	Transcriptional regulator
MXF72_10445	COG0745	RESPONSE REGULATOR receiver
MXF72_10475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MXF72_10480	COG0735	belongs to the Fur family
MXF72_10485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MXF72_10495	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MXF72_10500	COG1469	GTP cyclohydrolase I activity
MXF72_10505	COG0523	cobalamin synthesis protein
MXF72_10510	COG2378	regulation of single-species biofilm formation
MXF72_10520	COG1960	acyl-CoA dehydrogenase activity
MXF72_10530	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MXF72_10545	COG0583	DNA-binding transcription factor activity
MXF72_10560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MXF72_10565	COG3971	2-oxopent-4-enoate hydratase activity
MXF72_10625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MXF72_10655	COG0582	viral genome integration into host DNA
MXF72_10735	COG0582	viral genome integration into host DNA
MXF72_10740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MXF72_10740	COG0519	Catalyzes the synthesis of GMP from XMP
MXF72_10770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MXF72_10770	COG0047	phosphoribosylformylglycinamidine synthase activity
MXF72_10780	COG0613	PHP domain protein
MXF72_10795	COG0084	hydrolase, TatD family'
MXF72_10800	COG1136	(ABC) transporter
MXF72_10815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MXF72_10825	COG0385	Bile acid
MXF72_10830	COG0697	spore germination
MXF72_10835	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MXF72_10840	COG0840	transmembrane signaling receptor activity
MXF72_10850	COG4221	oxidoreductase activity
MXF72_10855	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MXF72_10860	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_10870	COG0316	Belongs to the HesB IscA family
MXF72_10880	COG1104	cysteine desulfurase activity
MXF72_10890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MXF72_10895	COG0556	nucleotide-excision repair
MXF72_10915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MXF72_10925	COG0740	serine-type endopeptidase activity
MXF72_10930	COG0544	peptidyl-prolyl cis-trans isomerase activity
MXF72_10935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MXF72_10950	COG0789	Transcriptional regulator
MXF72_10990	COG0471	metal ion transport
MXF72_10990	COG3273	potassium ion transport
MXF72_11000	COG2207	Transcriptional regulator
MXF72_11010	COG2171	N-acyltransferase activity
MXF72_11015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MXF72_11020	COG2890	protein-(glutamine-N5) methyltransferase activity
MXF72_11025	COG0488	(ABC) transporter
MXF72_11080	COG0210	DNA helicase
MXF72_11090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MXF72_11090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MXF72_11095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MXF72_11100	COG0196	riboflavin kinase activity
MXF72_11105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MXF72_11110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MXF72_11120	COG0756	dUTP diphosphatase activity
MXF72_11125	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
MXF72_11160	COG1403	HNH endonuclease
MXF72_11180	COG0559	Belongs to the binding-protein-dependent transport system permease family
MXF72_11200	COG3008	intermembrane lipid transfer
MXF72_11200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MXF72_11205	COG2995	paraquat-inducible protein a
MXF72_11210	COG0542	response to heat
MXF72_11215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MXF72_11220	COG1278	Cold shock
MXF72_11230	COG0183	Belongs to the thiolase family
MXF72_11245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MXF72_11250	COG1570	exodeoxyribonuclease VII activity
MXF72_11255	COG0811	peptide transport
MXF72_11260	COG0848	biopolymer transport protein
MXF72_11265	COG1663	tetraacyldisaccharide 4'-kinase activity
MXF72_11270	COG2835	tetraacyldisaccharide 4'-kinase activity
MXF72_11275	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MXF72_11280	COG0563	adenylate kinase activity
MXF72_11290	COG0728	peptidoglycan biosynthetic process
MXF72_11295	COG0268	Binds directly to 16S ribosomal RNA
MXF72_11300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MXF72_11310	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MXF72_11315	COG0745	RESPONSE REGULATOR receiver
MXF72_11320	COG2205	protein histidine kinase activity
MXF72_11325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MXF72_11335	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MXF72_11345	COG0519	Catalyzes the synthesis of GMP from XMP
MXF72_11345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MXF72_11350	COG1609	Transcriptional regulator
MXF72_11370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MXF72_11375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MXF72_11380	COG0137	argininosuccinate synthase activity
MXF72_11390	COG2832	Protein of unknown function (DUF454)
MXF72_11395	COG0494	nUDIX hydrolase
MXF72_11405	COG0626	cystathionine gamma-synthase activity
MXF72_11410	COG1522	sequence-specific DNA binding
MXF72_11425	COG2199	diguanylate cyclase activity
MXF72_11475	COG3772	lysozyme
MXF72_11485	COG0582	viral genome integration into host DNA
MXF72_11605	COG2814	Major facilitator Superfamily
MXF72_11610	COG0501	Belongs to the peptidase M48B family
MXF72_11620	COG0456	acetyltransferase
MXF72_11635	COG1490	D-aminoacyl-tRNA deacylase activity
MXF72_11640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MXF72_11650	COG2239	Acts as a magnesium transporter
MXF72_11655	COG0784	Response regulator, receiver
MXF72_11655	COG2198	Histidine kinase
MXF72_11655	COG2205	protein histidine kinase activity
MXF72_11660	COG3437	response regulator, receiver
MXF72_11665	COG1396	sequence-specific DNA binding
MXF72_11680	COG0477	Major facilitator Superfamily
MXF72_11685	COG1196	nuclear chromosome segregation
MXF72_11685	COG3264	Mechanosensitive ion channel
MXF72_11690	COG3264	Mechanosensitive ion channel
MXF72_11690	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MXF72_11700	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_11730	COG2828	Protein conserved in bacteria
MXF72_11740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MXF72_11745	COG1058	Belongs to the CinA family
MXF72_11745	COG1546	Belongs to the CinA family
MXF72_11750	COG1846	Transcriptional regulator
MXF72_11760	COG0069	glutamate synthase activity
MXF72_11775	COG1999	signal sequence binding
MXF72_11795	COG2252	PERMEase
MXF72_11800	COG1289	transmembrane transporter activity
MXF72_11815	COG0025	NhaP-type Na H and K H
MXF72_11850	COG4774	siderophore transport
MXF72_11855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MXF72_11860	COG3258	Cytochrome c
MXF72_11875	COG3278	Belongs to the heme-copper respiratory oxidase family
MXF72_11885	COG0642	Histidine kinase
MXF72_11890	COG1278	Cold shock
MXF72_11915	COG0446	pyridine nucleotide-disulphide oxidoreductase
MXF72_11955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MXF72_11960	COG3755	Protein conserved in bacteria
MXF72_11965	COG0583	DNA-binding transcription factor activity
MXF72_11985	COG1113	amino acid transport
MXF72_12005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MXF72_12005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MXF72_12035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_12045	COG1858	cytochrome C peroxidase
MXF72_12050	COG4771	TonB-dependent receptor
MXF72_12065	COG2824	Alkylphosphonate utilization operon protein PhnA
MXF72_12075	COG0583	DNA-binding transcription factor activity
MXF72_12080	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_12085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MXF72_12090	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MXF72_12095	COG4521	taurine ABC transporter
MXF72_12115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MXF72_12140	COG4128	Pfam Zonular occludens toxin
MXF72_12190	COG4974	Belongs to the 'phage' integrase family
MXF72_12205	COG2135	peptidase activity
MXF72_12215	COG3772	lysozyme
MXF72_12305	COG1783	phage Terminase large subunit
MXF72_12310	COG5484	DNA packaging
MXF72_12310	COG3728	DNA packaging
MXF72_12325	COG1802	Transcriptional regulator
MXF72_12325	COG4626	Terminase
MXF72_12455	COG0582	viral genome integration into host DNA
MXF72_12465	COG2610	gluconate transmembrane transporter activity
MXF72_12470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MXF72_12470	COG2010	Cytochrome c
MXF72_12475	COG2080	2 iron, 2 sulfur cluster binding
MXF72_12485	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_12500	COG0840	transmembrane signaling receptor activity
MXF72_12505	COG0840	transmembrane signaling receptor activity
MXF72_12510	COG2733	membrane
MXF72_12530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MXF72_12585	COG1191	sigma factor activity
MXF72_12590	COG1334	flagellar protein FlaG
MXF72_12615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MXF72_12620	COG1677	Flagellar hook-basal body complex protein FliE
MXF72_12625	COG1766	The M ring may be actively involved in energy transduction
MXF72_12640	COG1157	protein secretion by the type III secretion system
MXF72_12655	COG1580	Controls the rotational direction of flagella during chemotaxis
MXF72_12665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MXF72_12680	COG1987	bacterial-type flagellum assembly
MXF72_12690	COG2176	DNA-directed DNA polymerase activity
MXF72_12715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MXF72_12755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MXF72_12760	COG1558	bacterial-type flagellum-dependent cell motility
MXF72_12765	COG1815	bacterial-type flagellum-dependent cell motility
MXF72_12775	COG2747	anti-sigma28 factor FlgM
MXF72_12790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MXF72_12800	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MXF72_12805	COG0745	RESPONSE REGULATOR receiver
MXF72_12815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MXF72_12820	COG0840	transmembrane signaling receptor activity
MXF72_12825	COG0835	chemotaxis
MXF72_12835	COG1360	Flagellar Motor Protein
MXF72_12855	COG0791	NLP P60 protein
MXF72_12860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MXF72_12865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MXF72_12870	COG2314	TM2 domain
MXF72_12880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MXF72_12885	COG0659	secondary active sulfate transmembrane transporter activity
MXF72_12910	COG0640	Transcriptional regulator
MXF72_12920	COG3094	Invasion gene expression up-regulator, SirB
MXF72_12940	COG0697	spore germination
MXF72_12950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MXF72_12965	COG1283	sodium-dependent phosphate transmembrane transporter activity
MXF72_12970	COG0628	permease
MXF72_13015	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_13040	COG0247	lactate metabolic process
MXF72_13045	COG0277	FAD linked oxidase domain protein
MXF72_13050	COG0277	FAD linked oxidase domain protein
MXF72_13055	COG2186	Transcriptional regulator
MXF72_13105	COG1132	(ABC) transporter
MXF72_13130	COG0438	transferase activity, transferring glycosyl groups
MXF72_13145	COG0726	polysaccharide deacetylase
MXF72_13150	COG0438	transferase activity, transferring glycosyl groups
MXF72_13160	COG1643	Atp-dependent helicase
MXF72_13165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MXF72_13165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MXF72_13170	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MXF72_13175	COG4251	negative regulation of phosphorylation
MXF72_13175	COG5001	Diguanylate cyclase
MXF72_13175	COG2203	Gaf domain
MXF72_13175	COG3706	GGDEF domain
MXF72_13180	COG0704	Plays a role in the regulation of phosphate uptake
MXF72_13185	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MXF72_13190	COG1393	Belongs to the ArsC family
MXF72_13195	COG1177	transmembrane transport
MXF72_13200	COG1176	ABC-type spermidine putrescine transport system, permease component I
MXF72_13205	COG3842	ATPase activity
MXF72_13230	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_13235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MXF72_13240	COG1562	ergosterol biosynthetic process
MXF72_13245	COG1562	ergosterol biosynthetic process
MXF72_13250	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MXF72_13255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MXF72_13270	COG0436	Aminotransferase
MXF72_13280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MXF72_13285	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MXF72_13290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MXF72_13300	COG0305	Participates in initiation and elongation during chromosome replication
MXF72_13310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MXF72_13315	COG2965	DNA replication, synthesis of RNA primer
MXF72_13320	COG0360	Binds together with S18 to 16S ribosomal RNA
MXF72_13325	COG1469	GTP cyclohydrolase I activity
MXF72_13330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MXF72_13335	COG0142	geranyltranstransferase activity
MXF72_13340	COG1722	exodeoxyribonuclease VII activity
MXF72_13360	COG0501	Belongs to the peptidase M48B family
MXF72_13380	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MXF72_13390	COG1283	sodium-dependent phosphate transmembrane transporter activity
MXF72_13410	COG4215	(ABC) transporter
MXF72_13415	COG4160	amino acid transport
MXF72_13425	COG0446	pyridine nucleotide-disulphide oxidoreductase
MXF72_13430	COG1217	gtp-binding protein TYPA
MXF72_13435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MXF72_13440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MXF72_13450	COG0195	Participates in both transcription termination and antitermination
MXF72_13450	COG2251	uridine kinase activity
MXF72_13455	COG0779	Required for maturation of 30S ribosomal subunits
MXF72_13460	COG1187	pseudouridine synthase activity
MXF72_13465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MXF72_13510	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MXF72_13515	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_13520	COG3243	poly(R)-hydroxyalkanoic acid synthase
MXF72_13530	COG0564	pseudouridine synthase activity
MXF72_13555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_13560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MXF72_13560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MXF72_13575	COG1733	regulation of RNA biosynthetic process
MXF72_13585	COG1199	ATP-dependent helicase activity
MXF72_13590	COG2183	response to ionizing radiation
MXF72_13610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MXF72_13615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MXF72_13620	COG0508	dehydrogenase complex catalyzes the overall conversion of
MXF72_13625	COG0567	Dehydrogenase, E1 component
MXF72_13630	COG0280	phosphate acetyltransferase
MXF72_13630	COG0281	malic enzyme
MXF72_13640	COG0038	chloride channel
MXF72_13645	COG0372	Belongs to the citrate synthase family
MXF72_13650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MXF72_13655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MXF72_13660	COG1053	succinate dehydrogenase
MXF72_13670	COG2009	succinate dehydrogenase
MXF72_13675	COG2188	Transcriptional regulator
MXF72_13680	COG0039	L-malate dehydrogenase activity
MXF72_13700	COG3829	transcription factor binding
MXF72_13730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MXF72_13755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MXF72_13760	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_13770	COG0318	PFAM AMP-dependent synthetase and ligase
MXF72_13775	COG0183	Belongs to the thiolase family
MXF72_13785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_13815	COG1454	alcohol dehydrogenase
MXF72_13820	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_13825	COG3284	Transcriptional regulator
MXF72_13835	COG4172	Belongs to the ABC transporter superfamily
MXF72_13840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MXF72_13850	COG0747	negative chemotaxis
MXF72_13860	COG1960	acyl-CoA dehydrogenase activity
MXF72_13865	COG0598	Magnesium transport protein CorA
MXF72_13870	COG2363	Small membrane protein
MXF72_13875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MXF72_13880	COG2094	Belongs to the DNA glycosylase MPG family
MXF72_13895	COG0655	NAD(P)H dehydrogenase (quinone) activity
MXF72_13900	COG0435	Glutathione S-transferase
MXF72_13905	COG1304	FMN binding
MXF72_13920	COG4773	Receptor
MXF72_13950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MXF72_13960	COG3842	ATPase activity
MXF72_13965	COG4208	sulfate ABC transporter
MXF72_13985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MXF72_14000	COG0330	HflC and HflK could
MXF72_14025	COG0037	tRNA processing
MXF72_14030	COG0825	malonyl-CoA metabolic process
MXF72_14040	COG0215	cysteine-tRNA ligase activity
MXF72_14060	COG1968	undecaprenyl-diphosphatase activity
MXF72_14065	COG1253	flavin adenine dinucleotide binding
MXF72_14070	COG0483	inositol monophosphate 1-phosphatase activity
MXF72_14085	COG2031	fatty acid transporter
MXF72_14090	COG0154	amidase activity
MXF72_14135	COG0668	transmembrane transport
MXF72_14145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MXF72_14155	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_14165	COG1132	(ABC) transporter
MXF72_14170	COG0363	glucosamine-6-phosphate deaminase activity
MXF72_14175	COG1538	Outer membrane efflux protein
MXF72_14180	COG1136	(ABC) transporter
MXF72_14180	COG0577	efflux transmembrane transporter activity
MXF72_14185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MXF72_14195	COG3391	amine dehydrogenase activity
MXF72_14205	COG2850	peptidyl-arginine hydroxylation
MXF72_14210	COG3135	benzoate transporter
MXF72_14220	COG2124	cytochrome p450
MXF72_14225	COG0156	8-amino-7-oxononanoate synthase activity
MXF72_14235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MXF72_14250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MXF72_14255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MXF72_14260	COG1994	Peptidase M50
MXF72_14265	COG0009	L-threonylcarbamoyladenylate synthase
MXF72_14280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MXF72_14285	COG3327	negative regulation of DNA-templated transcription, initiation
MXF72_14290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MXF72_14320	COG1368	sulfuric ester hydrolase activity
MXF72_14335	COG2323	membrane
MXF72_14340	COG2010	Cytochrome c
MXF72_14345	COG1231	oxidoreductase activity
MXF72_14395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MXF72_14400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MXF72_14420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MXF72_14425	COG0248	Ppx GppA phosphatase
MXF72_14435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MXF72_14445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MXF72_14450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MXF72_14455	COG1534	Rna-binding protein
MXF72_14460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MXF72_14465	COG2233	PERMEase
MXF72_14485	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MXF72_14490	COG0505	Belongs to the CarA family
MXF72_14495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MXF72_14500	COG3391	amine dehydrogenase activity
MXF72_14520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MXF72_14555	COG1074	ATP-dependent DNA helicase activity
MXF72_14570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MXF72_14575	COG4149	molybdate abc transporter
MXF72_14580	COG0725	ABC transporter, periplasmic molybdate-binding protein
MXF72_14585	COG4974	Belongs to the 'phage' integrase family
MXF72_14590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MXF72_14595	COG2223	nitrite transmembrane transporter activity
MXF72_14605	COG2910	NAD(P)H-binding
MXF72_14610	COG1733	regulation of RNA biosynthetic process
MXF72_14655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MXF72_14660	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_14665	COG0583	DNA-binding transcription factor activity
MXF72_14670	COG0280	phosphate acetyltransferase
MXF72_14670	COG0281	malic enzyme
MXF72_14675	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_14685	COG0802	atpase or kinase
MXF72_14690	COG0860	N-Acetylmuramoyl-L-alanine amidase
MXF72_14695	COG0586	Pfam SNARE associated Golgi protein
MXF72_14700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MXF72_14705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MXF72_14710	COG1953	Uracil, thiamine, allantoin
MXF72_14715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MXF72_14720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MXF72_14730	COG0617	tRNA 3'-terminal CCA addition
MXF72_14735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MXF72_14740	COG1573	uracil-dna glycosylase
MXF72_14755	COG2814	Major facilitator Superfamily
MXF72_14765	COG1309	transcriptional regulator
MXF72_14775	COG1024	Enoyl-CoA hydratase
MXF72_14785	COG0752	glycyl-tRNA synthetase alpha subunit
MXF72_14790	COG0751	glycine-tRNA ligase activity
MXF72_14795	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MXF72_14800	COG0204	Acyl-transferase
MXF72_14815	COG0700	Nucleoside recognition
MXF72_14820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MXF72_14825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MXF72_14830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MXF72_14850	COG1126	abc transporter atp-binding protein
MXF72_14855	COG0765	amino acid transport
MXF72_14860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_14870	COG2011	ABC-type metal ion transport system permease component
MXF72_14875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MXF72_14890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MXF72_14890	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MXF72_14900	COG0318	PFAM AMP-dependent synthetase and ligase
MXF72_14905	COG1473	amidohydrolase
MXF72_14915	COG2239	Acts as a magnesium transporter
MXF72_14925	COG0653	protein targeting
MXF72_14930	COG0739	heme binding
MXF72_14930	COG0741	lytic transglycosylase activity
MXF72_14930	COG1196	nuclear chromosome segregation
MXF72_14940	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MXF72_14955	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MXF72_14960	COG1181	Belongs to the D-alanine--D-alanine ligase family
MXF72_14965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MXF72_14970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MXF72_14980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MXF72_14985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MXF72_14990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MXF72_15000	COG3116	cell division
MXF72_15005	COG0275	rRNA processing
MXF72_15010	COG2001	Belongs to the MraZ family
MXF72_15020	COG0488	(ABC) transporter
MXF72_15025	COG0633	Ferredoxin
MXF72_15030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MXF72_15035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MXF72_15040	COG0514	ATP-dependent DNA helicase (RecQ)
MXF72_15050	COG0038	chloride channel
MXF72_15060	COG1271	oxidase subunit
MXF72_15065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MXF72_15075	COG2894	cell division
MXF72_15080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MXF72_15100	COG0488	(ABC) transporter
MXF72_15110	COG1215	transferase activity, transferring glycosyl groups
MXF72_15115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MXF72_15130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MXF72_15140	COG0259	pyridoxamine-phosphate oxidase activity
MXF72_15145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MXF72_15150	COG0579	oxidoreductase
MXF72_15160	COG0405	Gamma-glutamyltransferase
MXF72_15170	COG1960	acyl-CoA dehydrogenase activity
MXF72_15175	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_15175	COG2030	dehydratase
MXF72_15180	COG0596	Alpha beta hydrolase
MXF72_15185	COG0009	L-threonylcarbamoyladenylate synthase
MXF72_15190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MXF72_15195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MXF72_15200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MXF72_15210	COG0521	Mo-molybdopterin cofactor biosynthetic process
MXF72_15235	COG0126	phosphoglycerate kinase activity
MXF72_15240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MXF72_15245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MXF72_15250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MXF72_15255	COG2732	(Barnase) inhibitor
MXF72_15265	COG0281	malic enzyme
MXF72_15265	COG0280	phosphate acetyltransferase
MXF72_15275	COG0436	Aminotransferase
MXF72_15285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MXF72_15290	COG0346	lactoylglutathione lyase activity
MXF72_15300	COG0477	Major facilitator Superfamily
MXF72_15310	COG0154	amidase activity
MXF72_15325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MXF72_15340	COG0583	DNA-binding transcription factor activity
MXF72_15355	COG4575	ribosome binding
MXF72_15365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MXF72_15370	COG2027	D-alanyl-D-alanine carboxypeptidase
MXF72_15375	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MXF72_15380	COG0343	queuine tRNA-ribosyltransferase activity
MXF72_15385	COG1862	Preprotein translocase
MXF72_15390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MXF72_15395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MXF72_15400	COG0024	Methionine aminopeptidase
MXF72_15410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MXF72_15415	COG1702	phosphate starvation-inducible protein PhoH
MXF72_15420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MXF72_15425	COG4535	Mg2 and Co2 transporter CorC
MXF72_15430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MXF72_15470	COG2814	Major facilitator Superfamily
MXF72_15505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MXF72_15510	COG0697	spore germination
MXF72_15525	COG0678	peroxiredoxin activity
MXF72_15565	COG0315	cyclic pyranopterin monophosphate synthase activity
MXF72_15575	COG0314	molybdopterin synthase activity
MXF72_15580	COG0521	Mo-molybdopterin cofactor biosynthetic process
MXF72_15585	COG0303	'Molybdopterin
MXF72_15595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MXF72_15600	COG1910	domain protein
MXF72_15615	COG3383	formate dehydrogenase (NAD+) activity
MXF72_15620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MXF72_15660	COG0463	Glycosyl transferase, family 2
MXF72_15665	COG2346	COG2346, Truncated hemoglobins
MXF72_15670	COG1959	2 iron, 2 sulfur cluster binding
MXF72_15675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MXF72_15680	COG1858	cytochrome C peroxidase
MXF72_15690	COG0411	ABC transporter
MXF72_15700	COG0559	Belongs to the binding-protein-dependent transport system permease family
MXF72_15720	COG2169	Transcriptional regulator
MXF72_15720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MXF72_15730	COG0785	Cytochrome C biogenesis protein
MXF72_15735	COG4235	cytochrome complex assembly
MXF72_15740	COG3088	subunit of a heme lyase
MXF72_15745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MXF72_15755	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MXF72_15765	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MXF72_15775	COG4133	protoheme IX ABC transporter activity
MXF72_15785	COG0583	DNA-binding transcription factor activity
MXF72_15790	COG0288	reversible hydration of carbon dioxide
MXF72_15805	COG0488	(ABC) transporter
MXF72_15830	COG0012	GTP binding
MXF72_15840	COG0193	aminoacyl-tRNA hydrolase activity
MXF72_15845	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MXF72_15850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MXF72_15865	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MXF72_15875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MXF72_15885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MXF72_15895	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MXF72_15900	COG0179	Fumarylacetoacetate (FAA) hydrolase
MXF72_15910	COG0277	FAD linked oxidase domain protein
MXF72_15920	COG0438	transferase activity, transferring glycosyl groups
MXF72_15925	COG0438	transferase activity, transferring glycosyl groups
MXF72_15930	COG0438	transferase activity, transferring glycosyl groups
MXF72_15945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MXF72_15950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MXF72_15960	COG3648	Uricase
MXF72_15960	COG3195	allantoin biosynthetic process
MXF72_15965	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MXF72_15970	COG0235	Class ii aldolase
MXF72_15975	COG1942	4-Oxalocrotonate Tautomerase
MXF72_15980	COG2233	PERMEase
MXF72_15990	COG0583	DNA-binding transcription factor activity
MXF72_15995	COG3960	tartronate-semialdehyde synthase activity
MXF72_16000	COG3622	Belongs to the hyi family
MXF72_16005	COG2084	Dehydrogenase
MXF72_16015	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MXF72_16020	COG0469	pyruvate kinase activity
MXF72_16025	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MXF72_16050	COG3278	Belongs to the heme-copper respiratory oxidase family
MXF72_16055	COG1765	OsmC-like protein
MXF72_16060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MXF72_16070	COG0509	glycine decarboxylation via glycine cleavage system
MXF72_16075	COG2081	HI0933 family
MXF72_16100	COG0489	protein tyrosine kinase activity
MXF72_16110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MXF72_16110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MXF72_16115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MXF72_16120	COG0583	DNA-binding transcription factor activity
MXF72_16125	COG3257	ureidoglycine aminohydrolase activity
MXF72_16130	COG0590	tRNA wobble adenosine to inosine editing
MXF72_16135	COG3391	amine dehydrogenase activity
MXF72_16150	COG0235	Class ii aldolase
MXF72_16155	COG0477	Major facilitator Superfamily
MXF72_16170	COG0387	Pfam Sodium calcium exchanger
MXF72_16180	COG0583	DNA-binding transcription factor activity
MXF72_16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MXF72_16205	COG1116	anion transmembrane transporter activity
MXF72_16215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MXF72_16235	COG1535	isochorismatase
MXF72_16235	COG3433	isochorismatase activity
MXF72_16255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MXF72_16270	COG1652	LysM domain
MXF72_16275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MXF72_16290	COG3023	N-Acetylmuramoyl-L-alanine amidase
MXF72_16300	COG3128	pkhd-type hydroxylase
MXF72_16305	COG4774	siderophore transport
MXF72_16310	COG0326	Molecular chaperone. Has ATPase activity
MXF72_16335	COG0583	DNA-binding transcription factor activity
MXF72_16345	COG0154	amidase activity
MXF72_16360	COG0477	Major facilitator Superfamily
MXF72_16370	COG4948	Mandelate Racemase Muconate Lactonizing
MXF72_16380	COG1418	mRNA catabolic process
MXF72_16390	COG1671	Belongs to the UPF0178 family
MXF72_16400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MXF72_16405	COG0861	Integral membrane protein TerC family
MXF72_16430	COG0395	ABC-type sugar transport system, permease component
MXF72_16450	COG1349	DNA-binding transcription factor activity
MXF72_16470	COG1113	amino acid transport
MXF72_16475	COG3844	kynureninase activity
MXF72_16480	COG1522	sequence-specific DNA binding
MXF72_16490	COG4585	Histidine kinase
MXF72_16510	COG1609	Transcriptional regulator
MXF72_16530	COG2186	Transcriptional regulator
MXF72_16535	COG1304	FMN binding
MXF72_16540	COG0277	FAD linked oxidase domain protein
MXF72_16545	COG2375	cellular response to nickel ion
MXF72_16545	COG1132	(ABC) transporter
MXF72_16550	COG1132	(ABC) transporter
MXF72_16555	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MXF72_16560	COG4605	iron ion homeostasis
MXF72_16565	COG4604	ABC transporter, ATP-binding protein
MXF72_16570	COG4607	ABC-type enterochelin transport system periplasmic component
MXF72_16575	COG4774	siderophore transport
MXF72_16595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MXF72_16610	COG1846	Transcriptional regulator
MXF72_16630	COG3685	Protein conserved in bacteria
MXF72_16640	COG0583	DNA-binding transcription factor activity
MXF72_16645	COG2814	Major facilitator Superfamily
MXF72_16650	COG0656	L-ascorbic acid biosynthetic process
MXF72_16655	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MXF72_16705	COG1121	(ABC) transporter
MXF72_16725	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MXF72_16755	COG0628	permease
MXF72_16765	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_16785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MXF72_16800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_16800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MXF72_16810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_16820	COG0129	dihydroxy-acid dehydratase activity
MXF72_16825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MXF72_16830	COG0730	response to heat
MXF72_16835	COG0275	rRNA processing
MXF72_16870	COG1950	PFAM Membrane protein of
MXF72_16875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MXF72_16880	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MXF72_16890	COG1560	Kdo2-lipid A biosynthetic process
MXF72_16895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MXF72_16905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MXF72_16910	COG0803	Belongs to the bacterial solute-binding protein 9 family
MXF72_16915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MXF72_16930	COG0735	belongs to the Fur family
MXF72_16935	COG0523	cobalamin synthesis protein
MXF72_16945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MXF72_16950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MXF72_16965	COG2096	Adenosyltransferase
MXF72_16980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MXF72_17005	COG1280	lysine exporter protein (LysE YggA)
MXF72_17045	COG0251	oxidation-reduction process
MXF72_17060	COG1346	cytolysis
MXF72_17065	COG2860	membrane
MXF72_17070	COG2223	nitrite transmembrane transporter activity
MXF72_17080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MXF72_17095	COG2918	glutathione biosynthetic process
MXF72_17125	COG2271	Major facilitator Superfamily
MXF72_17155	COG1012	belongs to the aldehyde dehydrogenase family
MXF72_17160	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MXF72_17170	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_17175	COG1414	Transcriptional regulator
MXF72_17190	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_17195	COG1250	3-hydroxyacyl-CoA dehydrogenase
MXF72_17200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MXF72_17210	COG1024	Enoyl-CoA hydratase
MXF72_17215	COG0067	glutamate synthase
MXF72_17215	COG0069	glutamate synthase activity
MXF72_17215	COG0070	glutamate synthase
MXF72_17235	COG0210	DNA helicase
MXF72_17240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MXF72_17245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MXF72_17270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MXF72_17280	COG3391	amine dehydrogenase activity
MXF72_17295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MXF72_17300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MXF72_17305	COG0765	amino acid transport
MXF72_17310	COG0765	amino acid transport
MXF72_17315	COG1126	abc transporter atp-binding protein
MXF72_17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_17325	COG0583	DNA-binding transcription factor activity
MXF72_17335	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MXF72_17340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MXF72_17360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MXF72_17380	COG0456	acetyltransferase
MXF72_17395	COG2311	Membrane
MXF72_17410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MXF72_17420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MXF72_17445	COG1253	flavin adenine dinucleotide binding
MXF72_17455	COG0583	DNA-binding transcription factor activity
MXF72_17465	COG2814	Major facilitator Superfamily
MXF72_17470	COG0513	Belongs to the DEAD box helicase family
MXF72_17475	COG2819	hydrolase of the alpha beta superfamily
MXF72_17480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MXF72_17485	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MXF72_17505	COG1250	3-hydroxyacyl-CoA dehydrogenase
MXF72_17520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MXF72_17535	COG0683	leucine binding
MXF72_17565	COG1021	2,3-dihydroxybenzoate-AMP ligase
MXF72_17570	COG1535	isochorismatase
MXF72_17570	COG3433	isochorismatase activity
MXF72_17575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MXF72_17590	COG1169	isochorismate synthase
MXF72_17595	COG3433	isochorismatase activity
MXF72_17595	COG1535	isochorismatase
MXF72_17600	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_17610	COG0840	transmembrane signaling receptor activity
MXF72_17620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MXF72_17625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MXF72_17630	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MXF72_17635	COG2967	ApaG domain
MXF72_17640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MXF72_17650	COG0546	phosphoglycolate phosphatase activity
MXF72_17660	COG0512	Glutamine amidotransferase of anthranilate synthase
MXF72_17665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MXF72_17670	COG0134	indole-3-glycerol-phosphate synthase activity
MXF72_17695	COG3154	lipid carrier protein
MXF72_17705	COG0826	peptidase U32
MXF72_17750	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MXF72_17760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MXF72_17765	COG1024	Enoyl-CoA hydratase
MXF72_17785	COG0321	lipoyl(octanoyl) transferase activity
MXF72_17790	COG2921	Belongs to the UPF0250 family
MXF72_17800	COG1686	Belongs to the peptidase S11 family
MXF72_17810	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MXF72_17810	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MXF72_17815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MXF72_17820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MXF72_17825	COG1278	Cold shock
MXF72_17835	COG0859	PFAM glycosyl transferase family 9
MXF72_17840	COG0583	DNA-binding transcription factor activity
MXF72_17845	COG4336	lyase activity
MXF72_17860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_17875	COG0697	spore germination
MXF72_17880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MXF72_17885	COG0242	peptide deformylase activity
MXF72_17890	COG0758	DNA mediated transformation
MXF72_17905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MXF72_17930	COG0559	Belongs to the binding-protein-dependent transport system permease family
MXF72_17950	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_17955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MXF72_17960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MXF72_17985	COG0252	asparaginase activity
MXF72_17990	COG0564	pseudouridine synthase activity
MXF72_18000	COG2358	TRAP transporter, solute receptor (TAXI family
MXF72_18010	COG1254	Belongs to the acylphosphatase family
MXF72_18020	COG4680	protein conserved in bacteria
MXF72_18045	COG0583	DNA-binding transcription factor activity
MXF72_18075	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_18085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_18090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MXF72_18110	COG1127	ABC transporter
MXF72_18115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MXF72_18145	COG0583	DNA-binding transcription factor activity
MXF72_18160	COG0154	amidase activity
MXF72_18175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MXF72_18190	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MXF72_18200	COG0513	Belongs to the DEAD box helicase family
MXF72_18205	COG1280	lysine exporter protein (LysE YggA)
MXF72_18210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MXF72_18220	COG2031	fatty acid transporter
MXF72_18235	COG0583	DNA-binding transcription factor activity
MXF72_18240	COG1335	isochorismatase
MXF72_18245	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MXF72_18255	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MXF72_18255	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_18260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MXF72_18265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MXF72_18270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MXF72_18275	COG0066	3-isopropylmalate dehydratase activity
MXF72_18280	COG4774	siderophore transport
MXF72_18285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MXF72_18300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MXF72_18325	COG0018	arginyl-trna synthetase
MXF72_18335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MXF72_18355	COG1960	acyl-CoA dehydrogenase activity
MXF72_18360	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MXF72_18365	COG0183	Belongs to the thiolase family
MXF72_18370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MXF72_18385	COG2922	Belongs to the Smg family
MXF72_18415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_18420	COG0028	Belongs to the TPP enzyme family
MXF72_18440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MXF72_18450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MXF72_18455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MXF72_18470	COG4149	molybdate abc transporter
MXF72_18510	COG0431	NADPH-dependent FMN reductase
MXF72_18515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MXF72_18530	COG1464	Belongs to the NlpA lipoprotein family
MXF72_18555	COG2011	ABC-type metal ion transport system permease component
MXF72_18560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MXF72_18565	COG1464	Belongs to the NlpA lipoprotein family
MXF72_18570	COG1464	Belongs to the NlpA lipoprotein family
MXF72_18580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MXF72_18585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MXF72_18595	COG0601	transmembrane transport
MXF72_18600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MXF72_18605	COG0444	Belongs to the ABC transporter superfamily
MXF72_18610	COG4608	Belongs to the ABC transporter superfamily
MXF72_18615	COG1595	DNA-templated transcription, initiation
MXF72_18640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MXF72_18665	COG1028	Short-chain dehydrogenase reductase Sdr
MXF72_18720	COG4638	Rieske (2fe-2S)
MXF72_18730	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MXF72_18735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MXF72_18740	COG0179	Fumarylacetoacetate (FAA) hydrolase
MXF72_18760	COG1846	Transcriptional regulator
MXF72_18780	COG2814	Major facilitator Superfamily
MXF72_18830	COG0523	cobalamin synthesis protein
MXF72_18845	COG3181	Tripartite tricarboxylate transporter family receptor
MXF72_18860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MXF72_18865	COG0596	Alpha beta hydrolase
MXF72_18865	COG0508	dehydrogenase complex catalyzes the overall conversion of
MXF72_18875	COG0318	PFAM AMP-dependent synthetase and ligase
MXF72_18890	COG0559	Belongs to the binding-protein-dependent transport system permease family
MXF72_18910	COG2271	Major facilitator Superfamily
MXF72_18915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MXF72_18920	COG1802	Transcriptional regulator
MXF72_18925	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MXF72_18935	COG0583	DNA-binding transcription factor activity
MXF72_18940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MXF72_18960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_18965	COG2186	Transcriptional regulator
MXF72_18980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MXF72_18995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MXF72_19000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MXF72_19025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MXF72_19040	COG1187	pseudouridine synthase activity
MXF72_19050	COG0592	DNA-directed DNA polymerase activity
MXF72_19055	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MXF72_19060	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MXF72_19065	COG0594	ribonuclease P activity
MXF72_19070	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MXF72_19075	COG0706	membrane insertase activity
MXF72_19080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MXF72_19110	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MXF72_19120	COG1136	(ABC) transporter
MXF72_19135	COG2205	protein histidine kinase activity
MXF72_19140	COG0745	RESPONSE REGULATOR receiver
MXF72_19150	COG0753	catalase activity
MXF72_19175	COG1335	isochorismatase
MXF72_19180	COG2309	aminopeptidase activity
MXF72_19185	COG0596	Alpha beta hydrolase
MXF72_19205	COG0559	Belongs to the binding-protein-dependent transport system permease family
MXF72_19240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MXF72_19245	COG3645	SOS response
MXF72_19285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MXF72_19295	COG0688	phosphatidylethanolamine metabolic process