locus-tag	class	description
J5J84_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5J84_00010	COG0592	DNA-directed DNA polymerase activity
J5J84_00020	COG1187	pseudouridine synthase activity
J5J84_00035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_00060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_00065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_00085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_00105	COG2070	2-Nitropropane dioxygenase
J5J84_00115	COG1960	acyl-CoA dehydrogenase activity
J5J84_00125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_00135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_00140	COG1802	Transcriptional regulator
J5J84_00145	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_00165	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5J84_00170	COG0583	DNA-binding transcription factor activity
J5J84_00180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_00190	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_00205	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_00215	COG0596	Alpha beta hydrolase
J5J84_00215	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5J84_00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_00235	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_00245	COG0697	spore germination
J5J84_00250	COG0583	DNA-binding transcription factor activity
J5J84_00260	COG3842	ATPase activity
J5J84_00270	COG0436	Aminotransferase
J5J84_00280	COG0523	cobalamin synthesis protein
J5J84_00335	COG1846	Transcriptional regulator
J5J84_00355	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5J84_00360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_00365	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J5J84_00375	COG4638	Rieske (2fe-2S)
J5J84_00430	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_00450	COG2207	Transcriptional regulator
J5J84_00480	COG1595	DNA-templated transcription, initiation
J5J84_00485	COG4608	Belongs to the ABC transporter superfamily
J5J84_00490	COG0444	Belongs to the ABC transporter superfamily
J5J84_00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5J84_00500	COG0601	transmembrane transport
J5J84_00510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5J84_00515	COG1595	DNA-templated transcription, initiation
J5J84_00520	COG3712	iron ion homeostasis
J5J84_00525	COG4774	siderophore transport
J5J84_00530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J5J84_00535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5J84_00555	COG1464	Belongs to the NlpA lipoprotein family
J5J84_00560	COG1464	Belongs to the NlpA lipoprotein family
J5J84_00565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5J84_00570	COG2011	ABC-type metal ion transport system permease component
J5J84_00595	COG1464	Belongs to the NlpA lipoprotein family
J5J84_00605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J5J84_00625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5J84_00630	COG0431	NADPH-dependent FMN reductase
J5J84_00665	COG4149	molybdate abc transporter
J5J84_00675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J5J84_00680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5J84_00690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_00710	COG0028	Belongs to the TPP enzyme family
J5J84_00715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_00750	COG2922	Belongs to the Smg family
J5J84_00765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5J84_00770	COG0183	Belongs to the thiolase family
J5J84_00775	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J5J84_00780	COG1960	acyl-CoA dehydrogenase activity
J5J84_00800	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5J84_00810	COG0018	arginyl-trna synthetase
J5J84_00830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_00845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J5J84_00850	COG4774	siderophore transport
J5J84_00855	COG0066	3-isopropylmalate dehydratase activity
J5J84_00860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5J84_00865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_00870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_00875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_00875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_00885	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_00890	COG1335	isochorismatase
J5J84_00895	COG0583	DNA-binding transcription factor activity
J5J84_00915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J5J84_00920	COG1280	lysine exporter protein (LysE YggA)
J5J84_00925	COG0513	Belongs to the DEAD box helicase family
J5J84_00935	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J5J84_00950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5J84_00965	COG0154	amidase activity
J5J84_00980	COG0583	DNA-binding transcription factor activity
J5J84_01010	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5J84_01015	COG1127	ABC transporter
J5J84_01020	COG3218	ABC-type transport auxiliary lipoprotein component
J5J84_01020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5J84_01035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5J84_01040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_01050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_01085	COG0583	DNA-binding transcription factor activity
J5J84_01105	COG3093	addiction module antidote protein HigA
J5J84_01130	COG2358	TRAP transporter, solute receptor (TAXI family
J5J84_01140	COG0564	pseudouridine synthase activity
J5J84_01145	COG0252	asparaginase activity
J5J84_01170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5J84_01175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5J84_01180	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_01200	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_01225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_01240	COG0758	DNA mediated transformation
J5J84_01245	COG0242	peptide deformylase activity
J5J84_01250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5J84_01255	COG0697	spore germination
J5J84_01270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_01285	COG4336	lyase activity
J5J84_01290	COG0583	DNA-binding transcription factor activity
J5J84_01295	COG0859	PFAM glycosyl transferase family 9
J5J84_01305	COG1278	Cold shock
J5J84_01310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J5J84_01315	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J5J84_01320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J5J84_01320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J5J84_01330	COG1686	Belongs to the peptidase S11 family
J5J84_01340	COG2921	Belongs to the UPF0250 family
J5J84_01345	COG0321	lipoyl(octanoyl) transferase activity
J5J84_01350	COG1024	Enoyl-CoA hydratase
J5J84_01355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5J84_01365	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J5J84_01410	COG0826	peptidase U32
J5J84_01420	COG3154	lipid carrier protein
J5J84_01445	COG0134	indole-3-glycerol-phosphate synthase activity
J5J84_01450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5J84_01455	COG0512	Glutamine amidotransferase of anthranilate synthase
J5J84_01465	COG0546	phosphoglycolate phosphatase activity
J5J84_01475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J5J84_01480	COG2967	ApaG domain
J5J84_01485	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J5J84_01490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_01495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5J84_01515	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_01520	COG1535	isochorismatase
J5J84_01520	COG3433	isochorismatase activity
J5J84_01525	COG1169	isochorismate synthase
J5J84_01540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J5J84_01540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J5J84_01545	COG3433	isochorismatase activity
J5J84_01545	COG1535	isochorismatase
J5J84_01550	COG1021	2,3-dihydroxybenzoate-AMP ligase
J5J84_01580	COG0683	leucine binding
J5J84_01595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_01630	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5J84_01635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5J84_01640	COG2819	hydrolase of the alpha beta superfamily
J5J84_01645	COG0513	Belongs to the DEAD box helicase family
J5J84_01650	COG2814	Major facilitator Superfamily
J5J84_01660	COG0583	DNA-binding transcription factor activity
J5J84_01670	COG1253	flavin adenine dinucleotide binding
J5J84_01705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5J84_01715	COG2311	Membrane
J5J84_01750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5J84_01770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_01775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J5J84_01785	COG0583	DNA-binding transcription factor activity
J5J84_01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_01800	COG0765	amino acid transport
J5J84_01805	COG0765	amino acid transport
J5J84_01810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_01825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5J84_01840	COG3391	amine dehydrogenase activity
J5J84_01850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5J84_01875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J5J84_01880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J5J84_01885	COG0210	DNA helicase
J5J84_01900	COG0070	glutamate synthase
J5J84_01900	COG0067	glutamate synthase
J5J84_01900	COG0069	glutamate synthase activity
J5J84_01905	COG1024	Enoyl-CoA hydratase
J5J84_01915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_01920	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5J84_01950	COG2918	glutathione biosynthetic process
J5J84_01960	COG2197	response regulator
J5J84_01965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_01975	COG2223	nitrite transmembrane transporter activity
J5J84_01980	COG2860	membrane
J5J84_01985	COG1346	cytolysis
J5J84_02000	COG0251	oxidation-reduction process
J5J84_02015	COG5295	Hep Hag repeat protein
J5J84_02030	COG1280	lysine exporter protein (LysE YggA)
J5J84_02040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5J84_02055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5J84_02070	COG2096	Adenosyltransferase
J5J84_02085	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J5J84_02090	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J5J84_02100	COG0523	cobalamin synthesis protein
J5J84_02105	COG0735	belongs to the Fur family
J5J84_02120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5J84_02125	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5J84_02130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J5J84_02140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5J84_02145	COG1560	Kdo2-lipid A biosynthetic process
J5J84_02155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5J84_02160	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5J84_02165	COG1950	PFAM Membrane protein of
J5J84_02200	COG0275	rRNA processing
J5J84_02205	COG0730	response to heat
J5J84_02210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J5J84_02215	COG0129	dihydroxy-acid dehydratase activity
J5J84_02220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J5J84_02240	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_02250	COG0628	permease
J5J84_02265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_02280	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_02305	COG1021	2,3-dihydroxybenzoate-AMP ligase
J5J84_02320	COG2814	Major facilitator Superfamily
J5J84_02330	COG0656	L-ascorbic acid biosynthetic process
J5J84_02335	COG2814	Major facilitator Superfamily
J5J84_02340	COG0583	DNA-binding transcription factor activity
J5J84_02350	COG3685	Protein conserved in bacteria
J5J84_02375	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5J84_02380	COG2814	Major facilitator Superfamily
J5J84_02385	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5J84_02390	COG0583	DNA-binding transcription factor activity
J5J84_02405	COG4774	siderophore transport
J5J84_02410	COG4607	ABC-type enterochelin transport system periplasmic component
J5J84_02415	COG4604	ABC transporter, ATP-binding protein
J5J84_02420	COG4605	iron ion homeostasis
J5J84_02425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5J84_02430	COG1132	(ABC) transporter
J5J84_02435	COG1132	(ABC) transporter
J5J84_02435	COG2375	cellular response to nickel ion
J5J84_02440	COG0277	FAD linked oxidase domain protein
J5J84_02445	COG1304	FMN binding
J5J84_02450	COG2186	Transcriptional regulator
J5J84_02470	COG1609	Transcriptional regulator
J5J84_02475	COG1522	sequence-specific DNA binding
J5J84_02480	COG3844	kynureninase activity
J5J84_02485	COG1113	amino acid transport
J5J84_02515	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_02520	COG1349	DNA-binding transcription factor activity
J5J84_02540	COG0395	ABC-type sugar transport system, permease component
J5J84_02545	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J5J84_02550	COG0861	Integral membrane protein TerC family
J5J84_02555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_02565	COG1671	Belongs to the UPF0178 family
J5J84_02575	COG1418	mRNA catabolic process
J5J84_02585	COG4948	Mandelate Racemase Muconate Lactonizing
J5J84_02595	COG0477	Major facilitator Superfamily
J5J84_02610	COG0154	amidase activity
J5J84_02620	COG0583	DNA-binding transcription factor activity
J5J84_02645	COG0326	Molecular chaperone. Has ATPase activity
J5J84_02650	COG4774	siderophore transport
J5J84_02655	COG3128	pkhd-type hydroxylase
J5J84_02665	COG3023	N-Acetylmuramoyl-L-alanine amidase
J5J84_02680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5J84_02695	COG1652	LysM domain
J5J84_02710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5J84_02755	COG0583	DNA-binding transcription factor activity
J5J84_02760	COG0387	Pfam Sodium calcium exchanger
J5J84_02775	COG0477	Major facilitator Superfamily
J5J84_02780	COG0235	Class ii aldolase
J5J84_02795	COG3391	amine dehydrogenase activity
J5J84_02800	COG0590	tRNA wobble adenosine to inosine editing
J5J84_02805	COG3257	ureidoglycine aminohydrolase activity
J5J84_02810	COG0583	DNA-binding transcription factor activity
J5J84_02815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5J84_02820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5J84_02820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5J84_02830	COG0489	protein tyrosine kinase activity
J5J84_02855	COG2081	HI0933 family
J5J84_02860	COG0509	glycine decarboxylation via glycine cleavage system
J5J84_02870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5J84_02875	COG1765	OsmC-like protein
J5J84_02880	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_02905	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
J5J84_02910	COG0469	pyruvate kinase activity
J5J84_02915	COG3193	protein, possibly involved in utilization of glycolate and propanediol
J5J84_02925	COG2084	Dehydrogenase
J5J84_02930	COG3622	Belongs to the hyi family
J5J84_02935	COG3960	tartronate-semialdehyde synthase activity
J5J84_02940	COG0583	DNA-binding transcription factor activity
J5J84_02950	COG2233	PERMEase
J5J84_02955	COG1942	4-Oxalocrotonate Tautomerase
J5J84_02960	COG0235	Class ii aldolase
J5J84_02970	COG3195	allantoin biosynthetic process
J5J84_02970	COG3648	Uricase
J5J84_02980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5J84_02985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J5J84_03000	COG0438	transferase activity, transferring glycosyl groups
J5J84_03010	COG0438	transferase activity, transferring glycosyl groups
J5J84_03020	COG0277	FAD linked oxidase domain protein
J5J84_03030	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5J84_03035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J5J84_03045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_03055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J5J84_03065	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J5J84_03080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5J84_03085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5J84_03090	COG0193	aminoacyl-tRNA hydrolase activity
J5J84_03100	COG0012	GTP binding
J5J84_03105	COG0582	viral genome integration into host DNA
J5J84_03120	COG4804	nuclease activity
J5J84_03125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J5J84_03145	COG0488	(ABC) transporter
J5J84_03160	COG0288	reversible hydration of carbon dioxide
J5J84_03165	COG0583	DNA-binding transcription factor activity
J5J84_03175	COG4133	protoheme IX ABC transporter activity
J5J84_03195	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J5J84_03205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5J84_03210	COG3088	subunit of a heme lyase
J5J84_03215	COG4235	cytochrome complex assembly
J5J84_03220	COG0785	Cytochrome C biogenesis protein
J5J84_03230	COG2169	Transcriptional regulator
J5J84_03230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5J84_03250	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_03260	COG0411	ABC transporter
J5J84_03270	COG1858	cytochrome C peroxidase
J5J84_03275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5J84_03280	COG1959	2 iron, 2 sulfur cluster binding
J5J84_03285	COG2346	COG2346, Truncated hemoglobins
J5J84_03290	COG0463	Glycosyl transferase, family 2
J5J84_03330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J5J84_03335	COG3383	formate dehydrogenase (NAD+) activity
J5J84_03350	COG1910	domain protein
J5J84_03355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J5J84_03365	COG0303	'Molybdopterin
J5J84_03370	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5J84_03375	COG0314	molybdopterin synthase activity
J5J84_03385	COG0315	cyclic pyranopterin monophosphate synthase activity
J5J84_03415	COG0678	peroxiredoxin activity
J5J84_03430	COG0697	spore germination
J5J84_03435	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5J84_03515	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5J84_03520	COG4535	Mg2 and Co2 transporter CorC
J5J84_03525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5J84_03530	COG1702	phosphate starvation-inducible protein PhoH
J5J84_03535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5J84_03550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5J84_03555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5J84_03560	COG1862	Preprotein translocase
J5J84_03565	COG0343	queuine tRNA-ribosyltransferase activity
J5J84_03570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5J84_03575	COG2027	D-alanyl-D-alanine carboxypeptidase
J5J84_03580	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J5J84_03590	COG4575	ribosome binding
J5J84_03605	COG0583	DNA-binding transcription factor activity
J5J84_03620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5J84_03635	COG0154	amidase activity
J5J84_03645	COG0477	Major facilitator Superfamily
J5J84_03660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J5J84_03670	COG0436	Aminotransferase
J5J84_03680	COG0281	malic enzyme
J5J84_03680	COG0280	phosphate acetyltransferase
J5J84_03690	COG2732	(Barnase) inhibitor
J5J84_03695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J5J84_03700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J5J84_03705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5J84_03710	COG0126	phosphoglycerate kinase activity
J5J84_03735	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5J84_03745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5J84_03750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J5J84_03755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J5J84_03760	COG0009	L-threonylcarbamoyladenylate synthase
J5J84_03765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_03770	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_03770	COG2030	dehydratase
J5J84_03775	COG1960	acyl-CoA dehydrogenase activity
J5J84_03785	COG0405	Gamma-glutamyltransferase
J5J84_03795	COG0579	oxidoreductase
J5J84_03800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5J84_03805	COG0259	pyridoxamine-phosphate oxidase activity
J5J84_03815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J5J84_03830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5J84_03835	COG1215	transferase activity, transferring glycosyl groups
J5J84_03845	COG0488	(ABC) transporter
J5J84_03865	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J5J84_03870	COG2894	cell division
J5J84_03880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5J84_03885	COG1271	oxidase subunit
J5J84_03890	COG1294	oxidase, subunit
J5J84_03895	COG0038	chloride channel
J5J84_03905	COG0514	ATP-dependent DNA helicase (RecQ)
J5J84_03910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5J84_03915	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5J84_03920	COG0633	Ferredoxin
J5J84_03925	COG0488	(ABC) transporter
J5J84_03935	COG2001	Belongs to the MraZ family
J5J84_03940	COG0275	rRNA processing
J5J84_03945	COG3116	cell division
J5J84_03955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5J84_03960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5J84_03965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5J84_03975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5J84_03980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5J84_03985	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5J84_03990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J5J84_04005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J5J84_04015	COG1196	nuclear chromosome segregation
J5J84_04015	COG0741	lytic transglycosylase activity
J5J84_04015	COG0739	heme binding
J5J84_04020	COG0653	protein targeting
J5J84_04030	COG2239	Acts as a magnesium transporter
J5J84_04040	COG1473	amidohydrolase
J5J84_04045	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_04055	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J5J84_04055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_04070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5J84_04075	COG2011	ABC-type metal ion transport system permease component
J5J84_04085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_04090	COG0765	amino acid transport
J5J84_04095	COG1126	abc transporter atp-binding protein
J5J84_04105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5J84_04120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_04125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5J84_04130	COG0700	Nucleoside recognition
J5J84_04145	COG0204	Acyl-transferase
J5J84_04150	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J5J84_04155	COG0751	glycine-tRNA ligase activity
J5J84_04160	COG0752	glycyl-tRNA synthetase alpha subunit
J5J84_04170	COG1024	Enoyl-CoA hydratase
J5J84_04180	COG1309	transcriptional regulator
J5J84_04190	COG2814	Major facilitator Superfamily
J5J84_04205	COG1573	uracil-dna glycosylase
J5J84_04210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5J84_04215	COG0617	tRNA 3'-terminal CCA addition
J5J84_04225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5J84_04230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5J84_04235	COG1953	Uracil, thiamine, allantoin
J5J84_04240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5J84_04245	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5J84_04250	COG0586	Pfam SNARE associated Golgi protein
J5J84_04255	COG0860	N-Acetylmuramoyl-L-alanine amidase
J5J84_04260	COG0802	atpase or kinase
J5J84_04270	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_04275	COG0280	phosphate acetyltransferase
J5J84_04275	COG0281	malic enzyme
J5J84_04280	COG0583	DNA-binding transcription factor activity
J5J84_04285	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_04290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_04310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_04335	COG1733	regulation of RNA biosynthetic process
J5J84_04340	COG2910	NAD(P)H-binding
J5J84_04350	COG2223	nitrite transmembrane transporter activity
J5J84_04355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5J84_04360	COG4974	Belongs to the 'phage' integrase family
J5J84_04365	COG0725	ABC transporter, periplasmic molybdate-binding protein
J5J84_04370	COG4149	molybdate abc transporter
J5J84_04375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5J84_04390	COG1074	ATP-dependent DNA helicase activity
J5J84_04425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_04445	COG3391	amine dehydrogenase activity
J5J84_04450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J5J84_04455	COG0505	Belongs to the CarA family
J5J84_04460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5J84_04480	COG2233	PERMEase
J5J84_04485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5J84_04490	COG1534	Rna-binding protein
J5J84_04495	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J5J84_04500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5J84_04510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5J84_04520	COG0248	Ppx GppA phosphatase
J5J84_04525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5J84_04545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5J84_04550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5J84_04600	COG1231	oxidoreductase activity
J5J84_04605	COG2010	Cytochrome c
J5J84_04610	COG2323	membrane
J5J84_04620	COG1368	sulfuric ester hydrolase activity
J5J84_04650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5J84_04655	COG3327	negative regulation of DNA-templated transcription, initiation
J5J84_04660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5J84_04675	COG0009	L-threonylcarbamoyladenylate synthase
J5J84_04680	COG1994	Peptidase M50
J5J84_04685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5J84_04690	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J5J84_04705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5J84_04715	COG0156	8-amino-7-oxononanoate synthase activity
J5J84_04720	COG2124	cytochrome p450
J5J84_04730	COG3135	benzoate transporter
J5J84_04735	COG2850	peptidyl-arginine hydroxylation
J5J84_04740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5J84_04745	COG3391	amine dehydrogenase activity
J5J84_04755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_04760	COG1136	(ABC) transporter
J5J84_04760	COG0577	efflux transmembrane transporter activity
J5J84_04765	COG1538	Outer membrane efflux protein
J5J84_04770	COG0363	glucosamine-6-phosphate deaminase activity
J5J84_04775	COG1132	(ABC) transporter
J5J84_04785	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_04795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5J84_04805	COG0668	transmembrane transport
J5J84_04815	COG0604	alcohol dehydrogenase
J5J84_04815	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_04815	COG3321	synthase
J5J84_04850	COG0154	amidase activity
J5J84_04855	COG2031	fatty acid transporter
J5J84_04870	COG0483	inositol monophosphate 1-phosphatase activity
J5J84_04875	COG1253	flavin adenine dinucleotide binding
J5J84_04880	COG1968	undecaprenyl-diphosphatase activity
J5J84_04905	COG0215	cysteine-tRNA ligase activity
J5J84_04915	COG0825	malonyl-CoA metabolic process
J5J84_04920	COG0037	tRNA processing
J5J84_04945	COG0330	HflC and HflK could
J5J84_04970	COG4208	sulfate ABC transporter
J5J84_04975	COG3842	ATPase activity
J5J84_04985	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J5J84_05015	COG1304	FMN binding
J5J84_05020	COG0435	Glutathione S-transferase
J5J84_05025	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5J84_05045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5J84_05050	COG2363	Small membrane protein
J5J84_05055	COG0598	Magnesium transport protein CorA
J5J84_05060	COG1960	acyl-CoA dehydrogenase activity
J5J84_05080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5J84_05085	COG4172	Belongs to the ABC transporter superfamily
J5J84_05095	COG3284	Transcriptional regulator
J5J84_05100	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_05105	COG1454	alcohol dehydrogenase
J5J84_05125	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_05135	COG0183	Belongs to the thiolase family
J5J84_05140	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_05150	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_05155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5J84_05180	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_05210	COG3829	transcription factor binding
J5J84_05215	COG0477	Major facilitator Superfamily
J5J84_05225	COG0039	L-malate dehydrogenase activity
J5J84_05230	COG2188	Transcriptional regulator
J5J84_05235	COG2009	succinate dehydrogenase
J5J84_05245	COG1053	succinate dehydrogenase
J5J84_05250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J5J84_05255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J5J84_05260	COG0372	Belongs to the citrate synthase family
J5J84_05265	COG2186	Transcriptional regulator
J5J84_05270	COG1620	l-lactate permease
J5J84_05275	COG0281	malic enzyme
J5J84_05275	COG0280	phosphate acetyltransferase
J5J84_05280	COG0567	Dehydrogenase, E1 component
J5J84_05285	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5J84_05290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5J84_05295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J5J84_05315	COG2183	response to ionizing radiation
J5J84_05320	COG1199	ATP-dependent helicase activity
J5J84_05330	COG1733	regulation of RNA biosynthetic process
J5J84_05350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_05360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_05360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_05375	COG0564	pseudouridine synthase activity
J5J84_05385	COG3243	poly(R)-hydroxyalkanoic acid synthase
J5J84_05390	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_05395	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
J5J84_05420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J5J84_05425	COG1187	pseudouridine synthase activity
J5J84_05430	COG0779	Required for maturation of 30S ribosomal subunits
J5J84_05435	COG2251	uridine kinase activity
J5J84_05435	COG0195	Participates in both transcription termination and antitermination
J5J84_05440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5J84_05445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5J84_05450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5J84_05455	COG1217	gtp-binding protein TYPA
J5J84_05460	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5J84_05470	COG4160	amino acid transport
J5J84_05475	COG4215	(ABC) transporter
J5J84_05495	COG1283	sodium-dependent phosphate transmembrane transporter activity
J5J84_05505	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J5J84_05520	COG0456	acetyltransferase
J5J84_05525	COG0501	Belongs to the peptidase M48B family
J5J84_05540	COG1722	exodeoxyribonuclease VII activity
J5J84_05545	COG0142	geranyltranstransferase activity
J5J84_05555	COG1469	GTP cyclohydrolase I activity
J5J84_05560	COG0360	Binds together with S18 to 16S ribosomal RNA
J5J84_05565	COG2965	DNA replication, synthesis of RNA primer
J5J84_05570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5J84_05580	COG0305	Participates in initiation and elongation during chromosome replication
J5J84_05590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5J84_05595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J5J84_05600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5J84_05610	COG0436	Aminotransferase
J5J84_05625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5J84_05630	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
J5J84_05635	COG1562	ergosterol biosynthetic process
J5J84_05640	COG1562	ergosterol biosynthetic process
J5J84_05645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5J84_05650	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_05675	COG3842	ATPase activity
J5J84_05680	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5J84_05685	COG1177	transmembrane transport
J5J84_05690	COG1393	Belongs to the ArsC family
J5J84_05695	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J5J84_05700	COG0704	Plays a role in the regulation of phosphate uptake
J5J84_05705	COG4251	negative regulation of phosphorylation
J5J84_05705	COG3706	GGDEF domain
J5J84_05705	COG5001	Diguanylate cyclase
J5J84_05705	COG2203	Gaf domain
J5J84_05710	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J5J84_05715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5J84_05715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J5J84_05720	COG1643	Atp-dependent helicase
J5J84_05730	COG0438	transferase activity, transferring glycosyl groups
J5J84_05735	COG0726	polysaccharide deacetylase
J5J84_05775	COG1132	(ABC) transporter
J5J84_05825	COG2186	Transcriptional regulator
J5J84_05830	COG0277	FAD linked oxidase domain protein
J5J84_05835	COG0277	FAD linked oxidase domain protein
J5J84_05840	COG0247	lactate metabolic process
J5J84_05865	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_05915	COG0628	permease
J5J84_05920	COG1283	sodium-dependent phosphate transmembrane transporter activity
J5J84_05935	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_05945	COG0697	spore germination
J5J84_05965	COG3094	Invasion gene expression up-regulator, SirB
J5J84_05975	COG0640	Transcriptional regulator
J5J84_06000	COG0659	secondary active sulfate transmembrane transporter activity
J5J84_06005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5J84_06015	COG2314	TM2 domain
J5J84_06020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5J84_06025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5J84_06030	COG0791	NLP P60 protein
J5J84_06050	COG1360	Flagellar Motor Protein
J5J84_06060	COG0835	chemotaxis
J5J84_06065	COG0840	transmembrane signaling receptor activity
J5J84_06070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5J84_06080	COG0745	RESPONSE REGULATOR receiver
J5J84_06085	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J5J84_06090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5J84_06095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5J84_06115	COG1120	ATPase activity
J5J84_06150	COG3486	L-lysine 6-monooxygenase (NADPH) activity
J5J84_06170	COG1815	bacterial-type flagellum-dependent cell motility
J5J84_06175	COG1558	bacterial-type flagellum-dependent cell motility
J5J84_06180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J5J84_06220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5J84_06235	COG0840	transmembrane signaling receptor activity
J5J84_06245	COG2176	DNA-directed DNA polymerase activity
J5J84_06255	COG1987	bacterial-type flagellum assembly
J5J84_06270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5J84_06280	COG1580	Controls the rotational direction of flagella during chemotaxis
J5J84_06295	COG1157	protein secretion by the type III secretion system
J5J84_06310	COG1766	The M ring may be actively involved in energy transduction
J5J84_06315	COG1677	Flagellar hook-basal body complex protein FliE
J5J84_06320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5J84_06345	COG1334	flagellar protein FlaG
J5J84_06350	COG1191	sigma factor activity
J5J84_06405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5J84_06425	COG2733	membrane
J5J84_06430	COG0840	transmembrane signaling receptor activity
J5J84_06435	COG0840	transmembrane signaling receptor activity
J5J84_06460	COG2610	gluconate transmembrane transporter activity
J5J84_06480	COG4974	Belongs to the 'phage' integrase family
J5J84_06540	COG4128	Pfam Zonular occludens toxin
J5J84_06555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5J84_06565	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5J84_06570	COG3657	addiction module killer protein
J5J84_06575	COG4521	taurine ABC transporter
J5J84_06580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J5J84_06585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_06590	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_06595	COG0583	DNA-binding transcription factor activity
J5J84_06625	COG2824	Alkylphosphonate utilization operon protein PhnA
J5J84_06645	COG1113	amino acid transport
J5J84_06665	COG0583	DNA-binding transcription factor activity
J5J84_06670	COG3755	Protein conserved in bacteria
J5J84_06710	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5J84_06735	COG1278	Cold shock
J5J84_06740	COG0642	Histidine kinase
J5J84_06750	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_06760	COG2863	cytochrome
J5J84_06765	COG3258	Cytochrome c
J5J84_06780	COG4774	siderophore transport
J5J84_06815	COG0025	NhaP-type Na H and K H
J5J84_06830	COG1289	transmembrane transporter activity
J5J84_06835	COG2252	PERMEase
J5J84_06855	COG1999	signal sequence binding
J5J84_06865	COG0069	glutamate synthase activity
J5J84_06875	COG1846	Transcriptional regulator
J5J84_06885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5J84_06925	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_06935	COG3264	Mechanosensitive ion channel
J5J84_06935	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J5J84_06940	COG3264	Mechanosensitive ion channel
J5J84_06940	COG1511	domain protein
J5J84_06945	COG0477	Major facilitator Superfamily
J5J84_06960	COG1396	sequence-specific DNA binding
J5J84_06965	COG3437	response regulator, receiver
J5J84_06970	COG2205	protein histidine kinase activity
J5J84_06970	COG0784	Response regulator, receiver
J5J84_06970	COG2198	Histidine kinase
J5J84_06975	COG2239	Acts as a magnesium transporter
J5J84_06985	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J5J84_06990	COG1490	D-aminoacyl-tRNA deacylase activity
J5J84_07005	COG0456	acetyltransferase
J5J84_07015	COG0501	Belongs to the peptidase M48B family
J5J84_07020	COG2814	Major facilitator Superfamily
J5J84_07075	COG2199	diguanylate cyclase activity
J5J84_07090	COG1522	sequence-specific DNA binding
J5J84_07095	COG0626	cystathionine gamma-synthase activity
J5J84_07105	COG0494	nUDIX hydrolase
J5J84_07110	COG2832	Protein of unknown function (DUF454)
J5J84_07120	COG0137	argininosuccinate synthase activity
J5J84_07125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J5J84_07130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5J84_07150	COG1609	Transcriptional regulator
J5J84_07160	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5J84_07170	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5J84_07175	COG2205	protein histidine kinase activity
J5J84_07180	COG0745	RESPONSE REGULATOR receiver
J5J84_07185	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5J84_07195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5J84_07200	COG0268	Binds directly to 16S ribosomal RNA
J5J84_07205	COG0728	peptidoglycan biosynthetic process
J5J84_07215	COG0563	adenylate kinase activity
J5J84_07220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5J84_07225	COG2835	tetraacyldisaccharide 4'-kinase activity
J5J84_07230	COG1663	tetraacyldisaccharide 4'-kinase activity
J5J84_07235	COG0848	biopolymer transport protein
J5J84_07240	COG0811	peptide transport
J5J84_07245	COG1570	exodeoxyribonuclease VII activity
J5J84_07250	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J5J84_07260	COG0183	Belongs to the thiolase family
J5J84_07270	COG1278	Cold shock
J5J84_07275	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5J84_07280	COG0542	response to heat
J5J84_07285	COG2995	paraquat-inducible protein a
J5J84_07290	COG3008	intermembrane lipid transfer
J5J84_07290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5J84_07310	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_07345	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
J5J84_07350	COG0756	dUTP diphosphatase activity
J5J84_07360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J5J84_07365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5J84_07370	COG0196	riboflavin kinase activity
J5J84_07375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5J84_07380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5J84_07380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5J84_07390	COG0210	DNA helicase
J5J84_07445	COG0488	(ABC) transporter
J5J84_07450	COG2890	protein-(glutamine-N5) methyltransferase activity
J5J84_07455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5J84_07460	COG2171	N-acyltransferase activity
J5J84_07470	COG2207	Transcriptional regulator
J5J84_07480	COG3273	potassium ion transport
J5J84_07480	COG0471	metal ion transport
J5J84_07665	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
J5J84_07705	COG0740	serine-type endopeptidase activity
J5J84_07845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_07850	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5J84_07855	COG0740	serine-type endopeptidase activity
J5J84_07865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J5J84_07875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5J84_07885	COG0556	nucleotide-excision repair
J5J84_07890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5J84_07900	COG1104	cysteine desulfurase activity
J5J84_07910	COG0316	Belongs to the HesB IscA family
J5J84_07925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5J84_07930	COG4221	oxidoreductase activity
J5J84_07940	COG0840	transmembrane signaling receptor activity
J5J84_07945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5J84_07950	COG0697	spore germination
J5J84_07955	COG0385	Bile acid
J5J84_07965	COG2831	hemolysin activation secretion protein
J5J84_07975	COG3210	domain, Protein
J5J84_08005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5J84_08020	COG1136	(ABC) transporter
J5J84_08025	COG0084	hydrolase, TatD family'
J5J84_08040	COG0613	PHP domain protein
J5J84_08050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5J84_08050	COG0047	phosphoribosylformylglycinamidine synthase activity
J5J84_08075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5J84_08075	COG0519	Catalyzes the synthesis of GMP from XMP
J5J84_08095	COG1196	nuclear chromosome segregation
J5J84_08105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J5J84_08115	COG3311	Transcriptional regulator
J5J84_08130	COG2076	Multidrug Resistance protein
J5J84_08135	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_08140	COG0583	DNA-binding transcription factor activity
J5J84_08155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J5J84_08165	COG1960	acyl-CoA dehydrogenase activity
J5J84_08170	COG0523	cobalamin synthesis protein
J5J84_08175	COG1469	GTP cyclohydrolase I activity
J5J84_08180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5J84_08190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5J84_08195	COG0735	belongs to the Fur family
J5J84_08200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5J84_08220	COG0745	RESPONSE REGULATOR receiver
J5J84_08235	COG1942	4-Oxalocrotonate Tautomerase
J5J84_08250	COG2070	2-Nitropropane dioxygenase
J5J84_08275	COG1309	transcriptional regulator
J5J84_08290	COG0625	glutathione transferase activity
J5J84_08295	COG0583	DNA-binding transcription factor activity
J5J84_08315	COG0625	glutathione transferase activity
J5J84_08320	COG0740	serine-type endopeptidase activity
J5J84_08370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5J84_08380	COG1960	acyl-CoA dehydrogenase activity
J5J84_08405	COG0640	Transcriptional regulator
J5J84_08430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_08455	COG3485	protocatechuate 3,4-dioxygenase
J5J84_08465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J5J84_08470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_08480	COG3135	benzoate transporter
J5J84_08490	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J5J84_08500	COG1136	(ABC) transporter
J5J84_08510	COG2197	response regulator
J5J84_08515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J5J84_08540	COG1846	Transcriptional regulator
J5J84_08545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_08550	COG2271	Major facilitator Superfamily
J5J84_08560	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J5J84_08570	COG0697	spore germination
J5J84_08595	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5J84_08600	COG0667	Aldo Keto reductase
J5J84_08615	COG0582	viral genome integration into host DNA
J5J84_08675	COG1272	protein, Hemolysin III
J5J84_08680	COG3422	double-strand break repair
J5J84_08705	COG0765	amino acid transport
J5J84_08710	COG0765	amino acid transport
J5J84_08715	COG1126	abc transporter atp-binding protein
J5J84_08770	COG2871	sodium ion transport
J5J84_08800	COG2814	Major facilitator Superfamily
J5J84_08805	COG1280	lysine exporter protein (LysE YggA)
J5J84_08825	COG0402	S-adenosylhomocysteine deaminase activity
J5J84_08850	COG0330	HflC and HflK could
J5J84_08855	COG1585	Membrane protein implicated in regulation of membrane protease activity
J5J84_08860	COG2226	methyltransferase
J5J84_08870	COG3042	response to heat
J5J84_08880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5J84_08900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5J84_08905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J5J84_08920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5J84_08925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5J84_08955	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5J84_08960	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5J84_08965	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J5J84_08970	COG0072	phenylalanine-tRNA ligase activity
J5J84_08970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5J84_08985	COG2833	Protein of unknown function (DUF455)
J5J84_08995	COG5265	(ABC) transporter
J5J84_09000	COG1959	2 iron, 2 sulfur cluster binding
J5J84_09005	COG0719	Fe-S assembly protein
J5J84_09010	COG0396	ATPase activity
J5J84_09015	COG0719	Fe-S assembly protein
J5J84_09025	COG0822	iron-sulfur transferase activity
J5J84_09030	COG2151	metal-sulfur cluster biosynthetic enzyme
J5J84_09045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5J84_09060	COG4197	protein conserved in bacteria, prophage-related
J5J84_09090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_09095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J5J84_09105	COG0745	RESPONSE REGULATOR receiver
J5J84_09150	COG3048	D-serine ammonia-lyase activity
J5J84_09155	COG3258	Cytochrome c
J5J84_09170	COG3949	Membrane
J5J84_09180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5J84_09195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5J84_09200	COG0569	domain protein
J5J84_09205	COG1902	pentaerythritol trinitrate reductase activity
J5J84_09215	COG1610	YqeY-like protein
J5J84_09220	COG0587	DNA-directed DNA polymerase activity
J5J84_09255	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_09260	COG0583	DNA-binding transcription factor activity
J5J84_09265	COG1686	Belongs to the peptidase S11 family
J5J84_09280	COG1360	Flagellar Motor Protein
J5J84_09290	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_09300	COG4221	oxidoreductase activity
J5J84_09310	COG0307	riboflavin synthase, alpha
J5J84_09355	COG2233	PERMEase
J5J84_09360	COG0071	Belongs to the small heat shock protein (HSP20) family
J5J84_09365	COG1473	amidohydrolase
J5J84_09405	COG2816	NAD+ diphosphatase activity
J5J84_09410	COG1561	YicC-like family, N-terminal region
J5J84_09425	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J5J84_09430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5J84_09435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5J84_09440	COG0174	glutamine synthetase
J5J84_09445	COG2153	protein acetylation
J5J84_09465	COG3842	ATPase activity
J5J84_09470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5J84_09475	COG1840	ABC-type Fe3 transport system, periplasmic component
J5J84_09490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5J84_09500	COG0783	Belongs to the Dps family
J5J84_09510	COG3842	ATPase activity
J5J84_09515	COG0395	ABC-type sugar transport system, permease component
J5J84_09520	COG1175	transmembrane transport
J5J84_09525	COG1653	transport
J5J84_09540	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5J84_09560	COG0625	glutathione transferase activity
J5J84_09570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5J84_09575	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_09580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J5J84_09585	COG0114	fumarate hydratase activity
J5J84_09590	COG2133	pyrroloquinoline quinone binding
J5J84_09595	COG2226	methyltransferase
J5J84_09600	COG0589	response to stress
J5J84_09605	COG4654	Cytochrome c, class I
J5J84_09610	COG2207	Transcriptional regulator
J5J84_09615	COG0235	Class ii aldolase
J5J84_09625	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_09630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_09635	COG2807	transmembrane transport
J5J84_09645	COG0583	DNA-binding transcription factor activity
J5J84_09675	COG0583	DNA-binding transcription factor activity
J5J84_09680	COG4974	Belongs to the 'phage' integrase family
J5J84_09695	COG2132	Multicopper oxidase
J5J84_09700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J5J84_09715	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_09740	COG3038	cytochrome b561
J5J84_09750	COG2353	YceI-like domain
J5J84_09755	COG1393	Belongs to the ArsC family
J5J84_09760	COG0625	glutathione transferase activity
J5J84_09780	COG0084	hydrolase, TatD family'
J5J84_09785	COG0470	DNA polymerase III
J5J84_09795	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J5J84_09815	COG1960	acyl-CoA dehydrogenase activity
J5J84_09820	COG2914	Belongs to the UPF0125 (RnfH) family
J5J84_09825	COG2867	negative regulation of translational initiation
J5J84_09830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5J84_09835	COG1252	NADH dehydrogenase
J5J84_09860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5J84_09865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5J84_09870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5J84_09880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5J84_09885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5J84_09895	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_09905	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5J84_09910	COG0575	Belongs to the CDS family
J5J84_09915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J5J84_09920	COG0233	cytoplasmic translational termination
J5J84_09925	COG0528	UMP kinase activity
J5J84_09930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5J84_09935	COG0052	Belongs to the universal ribosomal protein uS2 family
J5J84_09940	COG0024	Methionine aminopeptidase
J5J84_09945	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J5J84_09960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J5J84_09970	COG1286	toxin biosynthetic process
J5J84_09980	COG0285	dihydrofolate synthase activity
J5J84_09985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5J84_09990	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5J84_09995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J5J84_10005	COG4566	intracellular signal transduction
J5J84_10010	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5J84_10020	COG1999	signal sequence binding
J5J84_10025	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5J84_10030	COG0640	Transcriptional regulator
J5J84_10045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_10050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_10055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_10060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5J84_10065	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_10070	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_10090	COG0183	Belongs to the thiolase family
J5J84_10110	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5J84_10120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5J84_10125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_10130	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J5J84_10150	COG0183	Belongs to the thiolase family
J5J84_10155	COG0183	Belongs to the thiolase family
J5J84_10165	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J5J84_10200	COG0194	GDP metabolic process
J5J84_10205	COG1758	RNA polymerase activity
J5J84_10210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J5J84_10220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J5J84_10225	COG0739	heme binding
J5J84_10230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_10235	COG0584	glycerophosphoryl diester phosphodiesterase
J5J84_10240	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J5J84_10245	COG1187	pseudouridine synthase activity
J5J84_10250	COG3161	chorismate lyase activity
J5J84_10255	COG2814	Major facilitator Superfamily
J5J84_10260	COG0656	L-ascorbic acid biosynthetic process
J5J84_10270	COG0668	transmembrane transport
J5J84_10275	COG0165	Argininosuccinate lyase
J5J84_10290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_10300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5J84_10310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5J84_10315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J5J84_10320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5J84_10325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5J84_10330	COG2252	PERMEase
J5J84_10335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5J84_10355	COG0488	(ABC) transporter
J5J84_10360	COG1619	proteins homologs of microcin C7 resistance protein MccF
J5J84_10365	COG0590	tRNA wobble adenosine to inosine editing
J5J84_10370	COG1131	(ABC) transporter
J5J84_10375	COG0842	Transport permease protein
J5J84_10380	COG0840	transmembrane signaling receptor activity
J5J84_10385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_10385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_10390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5J84_10395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5J84_10400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_10410	COG2022	thiamine diphosphate biosynthetic process
J5J84_10430	COG1414	Transcriptional regulator
J5J84_10440	COG0730	response to heat
J5J84_10450	COG1666	GTP binding
J5J84_10455	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_10460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5J84_10465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5J84_10465	COG0519	Catalyzes the synthesis of GMP from XMP
J5J84_10470	COG2207	Transcriptional regulator
J5J84_10480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5J84_10485	COG0135	phosphoribosylanthranilate isomerase activity
J5J84_10490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_10500	COG0101	tRNA pseudouridine synthase activity
J5J84_10510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5J84_10535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5J84_10545	COG4566	intracellular signal transduction
J5J84_10560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5J84_10565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J5J84_10575	COG1295	ribonuclease BN
J5J84_10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5J84_10615	COG4964	Belongs to the GSP D family
J5J84_10660	COG2959	enzyme of heme biosynthesis
J5J84_10670	COG0181	hydroxymethylbilane synthase activity
J5J84_10675	COG0861	Integral membrane protein TerC family
J5J84_10680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5J84_10685	COG0045	succinate-CoA ligase (ADP-forming) activity
J5J84_10695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J5J84_10700	COG0583	DNA-binding transcription factor activity
J5J84_10705	COG2137	regulation of response to DNA damage stimulus
J5J84_10710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5J84_10725	COG0477	Major facilitator Superfamily
J5J84_10740	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_10745	COG1024	Enoyl-CoA hydratase
J5J84_10750	COG3162	membrane
J5J84_10765	COG0540	Belongs to the ATCase OTCase family
J5J84_10780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5J84_10795	COG2070	2-Nitropropane dioxygenase
J5J84_10805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5J84_10805	COG2111	Na H antiporter
J5J84_10810	COG1006	Multisubunit Na H antiporter MnhC subunit
J5J84_10815	COG0651	ATP synthesis coupled electron transport
J5J84_10825	COG2212	antiporter activity
J5J84_10840	COG0477	Major facilitator Superfamily
J5J84_10865	COG3158	transport of potassium into the cell
J5J84_10870	COG0642	Histidine kinase
J5J84_10895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5J84_10900	COG4208	sulfate ABC transporter
J5J84_10905	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5J84_10910	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J5J84_10925	COG1278	Cold shock
J5J84_10940	COG1648	precorrin-2 dehydrogenase activity
J5J84_10940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5J84_10945	COG2010	Cytochrome c
J5J84_10970	COG0535	radical SAM domain protein
J5J84_10975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5J84_10975	COG1648	precorrin-2 dehydrogenase activity
J5J84_10985	COG2010	Cytochrome c
J5J84_10990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_10995	COG0626	cystathionine gamma-synthase activity
J5J84_11000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5J84_11005	COG0557	exoribonuclease II activity
J5J84_11025	COG0765	amino acid transport
J5J84_11030	COG0765	amino acid transport
J5J84_11035	COG1126	abc transporter atp-binding protein
J5J84_11050	COG1850	ribulose-bisphosphate carboxylase activity
J5J84_11070	COG2375	cellular response to nickel ion
J5J84_11085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_11100	COG0583	DNA-binding transcription factor activity
J5J84_11105	COG3842	ATPase activity
J5J84_11110	COG1175	transmembrane transport
J5J84_11115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5J84_11120	COG1840	ABC-type Fe3 transport system, periplasmic component
J5J84_11140	COG0412	Dienelactone hydrolase
J5J84_11145	COG3530	Putative quorum-sensing-regulated virulence factor
J5J84_11150	COG0625	glutathione transferase activity
J5J84_11155	COG1741	Belongs to the pirin family
J5J84_11165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_11170	COG2814	Major facilitator Superfamily
J5J84_11175	COG2807	transmembrane transport
J5J84_11180	COG2207	Transcriptional regulator
J5J84_11185	COG3135	benzoate transporter
J5J84_11210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5J84_11220	COG0402	S-adenosylhomocysteine deaminase activity
J5J84_11230	COG0745	RESPONSE REGULATOR receiver
J5J84_11235	COG2205	protein histidine kinase activity
J5J84_11250	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5J84_11255	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J5J84_11260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5J84_11270	COG0330	HflC and HflK could
J5J84_11275	COG0330	HflC and HflK could
J5J84_11280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5J84_11285	COG1923	regulation of RNA biosynthetic process
J5J84_11295	COG1160	GTP binding
J5J84_11300	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_11305	COG2976	Protein conserved in bacteria
J5J84_11325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5J84_11330	COG0105	UTP biosynthetic process
J5J84_11340	COG0583	DNA-binding transcription factor activity
J5J84_11345	COG0697	spore germination
J5J84_11350	COG0336	Belongs to the RNA methyltransferase TrmD family
J5J84_11360	COG0228	four-way junction DNA binding
J5J84_11365	COG0425	Belongs to the sulfur carrier protein TusA family
J5J84_11370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5J84_11385	COG2351	hydroxyisourate hydrolase activity
J5J84_11420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_11445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5J84_11450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5J84_11475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5J84_11480	COG0601	transmembrane transport
J5J84_11510	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J5J84_11515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5J84_11520	COG0542	response to heat
J5J84_11525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5J84_11540	COG0348	domain, Protein
J5J84_11560	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_11570	COG2217	Heavy metal translocating P-type atpase
J5J84_11575	COG2224	Isocitrate lyase
J5J84_11580	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5J84_11580	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5J84_11600	COG1472	Belongs to the glycosyl hydrolase 3 family
J5J84_11605	COG0736	holo-[acyl-carrier-protein] synthase activity
J5J84_11615	COG2050	protein possibly involved in aromatic compounds catabolism
J5J84_11620	COG1024	Enoyl-CoA hydratase
J5J84_11625	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_11630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5J84_11635	COG2151	metal-sulfur cluster biosynthetic enzyme
J5J84_11640	COG3396	Phenylacetate-CoA oxygenase
J5J84_11645	COG3460	Phenylacetate-CoA oxygenase
J5J84_11650	COG3396	Phenylacetate-CoA oxygenase
J5J84_11655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J5J84_11660	COG0501	Belongs to the peptidase M48B family
J5J84_11665	COG1162	GTPase activity
J5J84_11675	COG0335	large ribosomal subunit rRNA binding
J5J84_11695	COG0450	alkyl hydroperoxide reductase
J5J84_11700	COG1960	acyl-CoA dehydrogenase activity
J5J84_11715	COG0123	including yeast histone deacetylase and acetoin utilization protein
J5J84_11720	COG2951	lytic endotransglycosylase activity
J5J84_11730	COG1596	polysaccharide export
J5J84_11730	COG1555	photosystem II stabilization
J5J84_11735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5J84_11740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J5J84_11745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J5J84_11765	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5J84_11770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5J84_11775	COG0287	Prephenate dehydrogenase
J5J84_11785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J5J84_11800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5J84_11820	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5J84_11830	COG4771	TonB-dependent receptor
J5J84_11845	COG0753	catalase activity
J5J84_11855	COG4335	DNA alkylation repair
J5J84_11865	COG0436	Aminotransferase
J5J84_11875	COG0251	oxidation-reduction process
J5J84_11880	COG1309	transcriptional regulator
J5J84_11935	COG0625	glutathione transferase activity
J5J84_11945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J5J84_11950	COG1280	lysine exporter protein (LysE YggA)
J5J84_11970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5J84_11980	COG2205	protein histidine kinase activity
J5J84_11980	COG0784	Response regulator, receiver
J5J84_11980	COG2198	Histidine kinase
J5J84_11985	COG2046	Belongs to the sulfate adenylyltransferase family
J5J84_11990	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J5J84_11995	COG0642	Histidine kinase
J5J84_12005	COG0840	transmembrane signaling receptor activity
J5J84_12010	COG2119	membrane
J5J84_12025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5J84_12030	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5J84_12045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5J84_12050	COG2321	neutral zinc metallopeptidase
J5J84_12065	COG2175	clavaminate synthase activity
J5J84_12070	COG1846	Transcriptional regulator
J5J84_12075	COG0347	Belongs to the P(II) protein family
J5J84_12080	COG0004	ammonium transporteR
J5J84_12085	COG3909	cytochrome
J5J84_12095	COG0625	glutathione transferase activity
J5J84_12100	COG0730	response to heat
J5J84_12105	COG0482	sulfurtransferase activity
J5J84_12110	COG0277	FAD linked oxidase domain protein
J5J84_12115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J5J84_12120	COG2879	small protein
J5J84_12125	COG1966	Carbon starvation protein
J5J84_12130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_12135	COG0765	amino acid transport
J5J84_12140	COG0765	amino acid transport
J5J84_12145	COG1126	abc transporter atp-binding protein
J5J84_12150	COG0028	Belongs to the TPP enzyme family
J5J84_12155	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_12160	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
J5J84_12165	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_12170	COG2226	methyltransferase
J5J84_12170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J5J84_12170	COG0596	Alpha beta hydrolase
J5J84_12175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_12180	COG1116	anion transmembrane transporter activity
J5J84_12195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_12210	COG5285	phytanoyl-CoA dioxygenase
J5J84_12215	COG0662	Cupin 2, conserved barrel domain protein
J5J84_12225	COG0456	acetyltransferase
J5J84_12230	COG1846	Transcriptional regulator
J5J84_12240	COG0312	modulator of DNA gyrase
J5J84_12255	COG0308	aminopeptidase N
J5J84_12260	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J5J84_12275	COG0473	3-isopropylmalate dehydrogenase activity
J5J84_12285	COG0433	COG0433 Predicted ATPase
J5J84_12290	COG0217	transcriptional regulatory protein
J5J84_12295	COG0151	Belongs to the GarS family
J5J84_12305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5J84_12310	COG0799	negative regulation of ribosome biogenesis
J5J84_12315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5J84_12320	COG0424	maF-like protein
J5J84_12340	COG0023	Translation Initiation Factor
J5J84_12350	COG2084	Dehydrogenase
J5J84_12355	COG0625	glutathione transferase activity
J5J84_12360	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5J84_12365	COG1047	Peptidyl-prolyl cis-trans
J5J84_12370	COG2003	Belongs to the UPF0758 family
J5J84_12375	COG1737	Transcriptional regulator
J5J84_12380	COG0477	Major facilitator Superfamily
J5J84_12390	COG2271	Major facilitator Superfamily
J5J84_12405	COG0534	Mate efflux family protein
J5J84_12410	COG4175	Glycine betaine
J5J84_12415	COG4176	ABC-type proline glycine betaine transport system permease component
J5J84_12425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5J84_12430	COG2814	Major facilitator Superfamily
J5J84_12435	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5J84_12440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5J84_12445	COG0495	leucyl-tRNA aminoacylation
J5J84_12455	COG1466	dna polymerase III delta subunit
J5J84_12460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5J84_12465	COG1981	membrane
J5J84_12480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J5J84_12490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J5J84_12495	COG0148	phosphopyruvate hydratase activity
J5J84_12505	COG2814	Major facilitator Superfamily
J5J84_12520	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5J84_12530	COG0504	CTP synthase activity
J5J84_12565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5J84_12575	COG0791	NLP P60 protein
J5J84_12585	COG0583	DNA-binding transcription factor activity
J5J84_12595	COG0583	DNA-binding transcription factor activity
J5J84_12605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5J84_12620	COG1045	serine acetyltransferase
J5J84_12635	COG1381	Involved in DNA repair and RecF pathway recombination
J5J84_12640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J5J84_12645	COG0571	ribonuclease III activity
J5J84_12660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5J84_12680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5J84_12685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5J84_12690	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_12695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5J84_12700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5J84_12710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5J84_12715	COG1399	metal-binding, possibly nucleic acid-binding protein
J5J84_12720	COG0424	maF-like protein
J5J84_12730	COG3023	N-Acetylmuramoyl-L-alanine amidase
J5J84_12735	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J5J84_12740	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J5J84_12745	COG0546	phosphoglycolate phosphatase activity
J5J84_12750	COG0564	pseudouridine synthase activity
J5J84_12755	COG1530	ribonuclease E activity
J5J84_12760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J5J84_12765	COG0159	tryptophan synthase activity
J5J84_12770	COG0133	tryptophan synthase activity
J5J84_12775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J5J84_12785	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J5J84_12790	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5J84_12800	COG2878	Part of a membrane complex involved in electron transport
J5J84_12805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J5J84_12810	COG1129	ABC transporter
J5J84_12815	COG3047	cAMP biosynthetic process
J5J84_12840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5J84_12845	COG2917	probably involved in intracellular septation
J5J84_12855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5J84_12860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5J84_12870	COG1196	nuclear chromosome segregation
J5J84_12880	COG1573	uracil-dna glycosylase
J5J84_12885	COG1214	PFAM Peptidase M22, glycoprotease
J5J84_12900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5J84_12905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5J84_12910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5J84_12915	COG0560	Phosphoserine phosphatase
J5J84_12930	COG1007	ATP synthesis coupled electron transport
J5J84_12945	COG0713	ATP synthesis coupled electron transport
J5J84_12955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_12960	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5J84_12965	COG1034	ATP synthesis coupled electron transport
J5J84_12980	COG0649	NAD binding
J5J84_12985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_12990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_12995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5J84_13005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_13020	COG0149	triose-phosphate isomerase activity
J5J84_13025	COG0604	alcohol dehydrogenase
J5J84_13045	COG1185	polyribonucleotide nucleotidyltransferase activity
J5J84_13050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5J84_13055	COG1183	phosphatidylcholine synthase activity
J5J84_13060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5J84_13065	COG0440	acetolactate synthase activity
J5J84_13070	COG0028	Belongs to the TPP enzyme family
J5J84_13075	COG1289	transmembrane transporter activity
J5J84_13080	COG3022	response to hydroperoxide
J5J84_13085	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_13095	COG3772	lysozyme
J5J84_13105	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5J84_13105	COG2755	lipolytic protein G-D-S-L family
J5J84_13230	COG3728	DNA packaging
J5J84_13365	COG0582	viral genome integration into host DNA
J5J84_13385	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5J84_13390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5J84_13395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J5J84_13400	COG1674	ftsk spoiiie
J5J84_13405	COG0492	ferredoxin-NADP+ reductase activity
J5J84_13425	COG0477	Major facilitator Superfamily
J5J84_13445	COG2272	Belongs to the type-B carboxylesterase lipase family
J5J84_13450	COG1960	acyl-CoA dehydrogenase activity
J5J84_13475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5J84_13495	COG2204	response regulator
J5J84_13535	COG4964	Belongs to the GSP D family
J5J84_13595	COG0612	Peptidase, M16
J5J84_13600	COG0484	heat shock protein binding
J5J84_13605	COG0443	Heat shock 70 kDa protein
J5J84_13610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5J84_13615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J5J84_13620	COG1420	regulation of RNA biosynthetic process
J5J84_13630	COG0497	DNA recombination
J5J84_13635	COG0735	belongs to the Fur family
J5J84_13640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5J84_13645	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5J84_13670	COG0477	Major facilitator Superfamily
J5J84_13680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J5J84_13710	COG1538	Outer membrane efflux protein
J5J84_13740	COG2814	Major facilitator Superfamily
J5J84_13750	COG2819	hydrolase of the alpha beta superfamily
J5J84_13770	COG1454	alcohol dehydrogenase
J5J84_13805	COG1414	Transcriptional regulator
J5J84_13810	COG0513	Belongs to the DEAD box helicase family
J5J84_13815	COG3657	addiction module killer protein
J5J84_13820	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5J84_13825	COG0583	DNA-binding transcription factor activity
J5J84_13830	COG4638	Rieske (2fe-2S)
J5J84_13835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J5J84_13850	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5J84_13865	COG3971	2-oxopent-4-enoate hydratase activity
J5J84_13870	COG4569	acetaldehyde dehydrogenase (acetylating) activity
J5J84_13875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5J84_13880	COG2814	Major facilitator Superfamily
J5J84_13895	COG0154	amidase activity
J5J84_13900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_13905	COG2814	Major facilitator Superfamily
J5J84_13935	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_13945	COG0842	Transport permease protein
J5J84_13950	COG0842	Transport permease protein
J5J84_13950	COG1129	ABC transporter
J5J84_13955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_13965	COG3243	poly(R)-hydroxyalkanoic acid synthase
J5J84_13975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J5J84_13980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5J84_13985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5J84_14000	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5J84_14015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5J84_14020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J5J84_14030	COG0789	Transcriptional regulator
J5J84_14040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5J84_14085	COG3278	Belongs to the heme-copper respiratory oxidase family
J5J84_14090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_14110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J5J84_14160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J5J84_14225	COG0516	GMP reductase activity
J5J84_14225	COG0517	IMP dehydrogenase activity
J5J84_14235	COG1027	Aspartate ammonia-lyase
J5J84_14240	COG1846	Transcriptional regulator
J5J84_14255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5J84_14260	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J5J84_14275	COG1414	Transcriptional regulator
J5J84_14295	COG0513	Belongs to the DEAD box helicase family
J5J84_14315	COG0429	hydrolase of the alpha beta-hydrolase fold
J5J84_14340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5J84_14350	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J5J84_14360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5J84_14365	COG0632	four-way junction helicase activity
J5J84_14375	COG2255	four-way junction helicase activity
J5J84_14385	COG0418	dihydroorotase activity
J5J84_14395	COG0415	Belongs to the DNA photolyase family
J5J84_14455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5J84_14460	COG4654	Cytochrome c, class I
J5J84_14500	COG1177	transmembrane transport
J5J84_14505	COG3842	ATPase activity
J5J84_14510	COG1840	ABC-type Fe3 transport system, periplasmic component
J5J84_14515	COG2084	Dehydrogenase
J5J84_14530	COG0494	nUDIX hydrolase
J5J84_14535	COG0442	prolyl-tRNA aminoacylation
J5J84_14540	COG0824	Thioesterase
J5J84_14545	COG0811	peptide transport
J5J84_14560	COG0823	Involved in the tonB-independent uptake of proteins
J5J84_14575	COG0596	Alpha beta hydrolase
J5J84_14600	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5J84_14605	COG4603	Belongs to the binding-protein-dependent transport system permease family
J5J84_14610	COG3845	ABC transporter
J5J84_14630	COG0427	acetyl-CoA hydrolase
J5J84_14635	COG0583	DNA-binding transcription factor activity
J5J84_14640	COG3634	alkyl hydroperoxide reductase activity
J5J84_14655	COG0697	spore germination
J5J84_14660	COG0175	sulfate reduction
J5J84_14680	COG1012	belongs to the aldehyde dehydrogenase family
J5J84_14685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5J84_14690	COG5383	Protein conserved in bacteria
J5J84_14700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J5J84_14715	COG0583	DNA-binding transcription factor activity
J5J84_14720	COG1741	Belongs to the pirin family
J5J84_14725	COG3706	GGDEF domain
J5J84_14730	COG0154	amidase activity
J5J84_14740	COG3712	iron ion homeostasis
J5J84_14745	COG1595	DNA-templated transcription, initiation
J5J84_14755	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5J84_14765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J5J84_14770	COG0284	orotidine-5'-phosphate decarboxylase activity
J5J84_14790	COG1414	Transcriptional regulator
J5J84_14800	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J5J84_14810	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5J84_14815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5J84_14840	COG0742	ribosomal rna small subunit methyltransferase
J5J84_14845	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J5J84_14850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J5J84_14880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
J5J84_14905	COG1335	isochorismatase
J5J84_14910	COG2309	aminopeptidase activity
J5J84_14915	COG0596	Alpha beta hydrolase
J5J84_14920	COG2010	Cytochrome c
J5J84_14920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5J84_14925	COG2080	2 iron, 2 sulfur cluster binding
J5J84_14930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5J84_14930	COG2010	Cytochrome c
J5J84_14940	COG0410	ABC transporter
J5J84_14945	COG0411	ABC transporter
J5J84_14970	COG3706	GGDEF domain
J5J84_15000	COG1234	tRNA 3'-trailer cleavage
J5J84_15005	COG2188	Transcriptional regulator
J5J84_15015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5J84_15025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5J84_15025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5J84_15030	COG3608	succinylglutamate desuccinylase aspartoacylase
J5J84_15030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J5J84_15035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5J84_15045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5J84_15075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_15110	COG1335	isochorismatase
J5J84_15115	COG2309	aminopeptidase activity
J5J84_15120	COG0596	Alpha beta hydrolase
J5J84_15135	COG1120	ATPase activity
J5J84_15140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5J84_15150	COG4206	TonB-dependent receptor
J5J84_15155	COG2031	fatty acid transporter
J5J84_15160	COG0583	DNA-binding transcription factor activity
J5J84_15165	COG0402	S-adenosylhomocysteine deaminase activity
J5J84_15170	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_15190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5J84_15195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5J84_15200	COG0328	RNA-DNA hybrid ribonuclease activity
J5J84_15205	COG2226	methyltransferase
J5J84_15210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5J84_15215	COG0741	lytic transglycosylase activity
J5J84_15215	COG1388	LysM domain
J5J84_15235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J5J84_15260	COG2204	response regulator
J5J84_15265	COG4191	Histidine kinase
J5J84_15270	COG1301	dicarboxylic acid transport
J5J84_15280	COG1054	Belongs to the UPF0176 family
J5J84_15305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5J84_15330	COG0604	alcohol dehydrogenase
J5J84_15360	COG1902	pentaerythritol trinitrate reductase activity
J5J84_15370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5J84_15375	COG1454	alcohol dehydrogenase
J5J84_15395	COG0583	DNA-binding transcription factor activity
J5J84_15420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_15435	COG1393	Belongs to the ArsC family
J5J84_15440	COG0431	NADPH-dependent FMN reductase
J5J84_15445	COG0745	RESPONSE REGULATOR receiver
J5J84_15450	COG0642	Histidine kinase
J5J84_15465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5J84_15465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5J84_15470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5J84_15475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5J84_15480	COG1881	PFAM PEBP family protein
J5J84_15485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5J84_15490	COG0739	heme binding
J5J84_15495	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J5J84_15500	COG0316	Belongs to the HesB IscA family
J5J84_15510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5J84_15515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5J84_15520	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5J84_15525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_15530	COG0312	modulator of DNA gyrase
J5J84_15535	COG3028	Belongs to the UPF0307 family
J5J84_15560	COG4191	Histidine kinase
J5J84_15560	COG2205	protein histidine kinase activity
J5J84_15560	COG0745	RESPONSE REGULATOR receiver
J5J84_15565	COG4566	intracellular signal transduction
J5J84_15570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5J84_15600	COG0762	integral membrane protein
J5J84_15610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5J84_15610	COG2169	Transcriptional regulator
J5J84_15615	COG3133	Outer membrane lipoprotein
J5J84_15620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5J84_15635	COG0439	Biotin carboxylase
J5J84_15640	COG0511	ligase activity, forming carbon-carbon bonds
J5J84_15645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5J84_15655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5J84_15660	COG3150	esterase
J5J84_15675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5J84_15680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5J84_15690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5J84_15705	COG1678	Uncharacterized ACR, COG1678
J5J84_15720	COG0352	thiamine-phosphate diphosphorylase activity
J5J84_15725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5J84_15740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5J84_15750	COG3237	CsbD-like
J5J84_15755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5J84_15760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5J84_15765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5J84_15770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5J84_15795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5J84_15810	COG1126	abc transporter atp-binding protein
J5J84_15815	COG0765	amino acid transport
J5J84_15820	COG4597	amino acid ABC transporter
J5J84_15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5J84_15830	COG2884	Cell division ATP-binding protein ftsE
J5J84_15835	COG2177	Part of the ABC transporter FtsEX involved in
J5J84_15845	COG0772	Belongs to the SEDS family
J5J84_15850	COG0768	penicillin binding
J5J84_15860	COG1792	Involved in formation and maintenance of cell shape
J5J84_15865	COG1077	Cell shape determining protein MreB Mrl
J5J84_15870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5J84_15875	COG0154	amidase activity
J5J84_15880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5J84_15885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5J84_15890	COG0583	DNA-binding transcription factor activity
J5J84_15895	COG2259	Doxx family
J5J84_15900	COG3384	dioxygenase
J5J84_15910	COG3245	cytochrome
J5J84_15925	COG3604	Transcriptional regulator
J5J84_15940	COG0786	glutamate:sodium symporter activity
J5J84_15945	COG0142	geranyltranstransferase activity
J5J84_15955	COG0494	nUDIX hydrolase
J5J84_15960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J5J84_15985	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J5J84_15990	COG0237	dephospho-CoA kinase activity
J5J84_16005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5J84_16010	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J5J84_16020	COG0477	Major facilitator Superfamily
J5J84_16035	COG4206	TonB-dependent receptor
J5J84_16040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5J84_16055	COG1595	DNA-templated transcription, initiation
J5J84_16065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J5J84_16085	COG0598	Magnesium transport protein CorA
J5J84_16100	COG2022	thiamine diphosphate biosynthetic process
J5J84_16105	COG0351	phosphomethylpyrimidine kinase
J5J84_16110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5J84_16115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5J84_16120	COG1538	Outer membrane efflux protein
J5J84_16125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J5J84_16135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5J84_16150	COG2226	methyltransferase
J5J84_16155	COG0745	RESPONSE REGULATOR receiver
J5J84_16170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J5J84_16175	COG1984	allophanate hydrolase subunit 2
J5J84_16180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5J84_16185	COG1238	metal cluster binding
J5J84_16210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J5J84_16215	COG4988	ABC transporter
J5J84_16225	COG1294	oxidase, subunit
J5J84_16230	COG1271	oxidase subunit
J5J84_16245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J5J84_16260	COG1137	ATPase activity
J5J84_16270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5J84_16275	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5J84_16280	COG1660	Displays ATPase and GTPase activities
J5J84_16290	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5J84_16295	COG0792	nuclease activity
J5J84_16300	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J5J84_16315	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5J84_16335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J5J84_16340	COG0793	Belongs to the peptidase S41A family
J5J84_16350	COG0588	phosphoglycerate mutase activity
J5J84_16355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J5J84_16365	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J5J84_16370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5J84_16375	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_16380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J5J84_16385	COG1040	competence protein
J5J84_16390	COG2226	methyltransferase
J5J84_16395	COG4771	TonB-dependent receptor
J5J84_16400	COG0745	RESPONSE REGULATOR receiver
J5J84_16405	COG2205	protein histidine kinase activity
J5J84_16415	COG2204	response regulator
J5J84_16430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5J84_16430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5J84_16435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5J84_16445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5J84_16450	COG3473	Maleate cis-trans isomerase
J5J84_16465	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J5J84_16535	COG0438	transferase activity, transferring glycosyl groups
J5J84_16540	COG0500	methyltransferase
J5J84_16565	COG3328	transposase activity
J5J84_16570	COG1215	transferase activity, transferring glycosyl groups
J5J84_16580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5J84_16585	COG3307	-O-antigen
J5J84_16595	COG1088	dTDP-glucose 4,6-dehydratase activity
J5J84_16600	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5J84_16620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5J84_16630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5J84_16635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5J84_16640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5J84_16655	COG0356	it plays a direct role in the translocation of protons across the membrane
J5J84_16665	COG1024	Enoyl-CoA hydratase
J5J84_16680	COG0037	tRNA processing
J5J84_16685	COG0163	prenyltransferase activity
J5J84_16690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J5J84_16695	COG2890	protein-(glutamine-N5) methyltransferase activity
J5J84_16720	COG3550	peptidyl-serine autophosphorylation
J5J84_16735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5J84_16740	COG2264	protein methyltransferase activity
J5J84_16745	COG4773	Receptor
J5J84_16765	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J5J84_16790	COG3180	Ammonia monooxygenase
J5J84_16810	COG5002	protein histidine kinase activity
J5J84_16825	COG0477	Major facilitator Superfamily
J5J84_16830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_16855	COG1116	anion transmembrane transporter activity
J5J84_16885	COG0437	4 iron, 4 sulfur cluster binding
J5J84_16890	COG2864	formate dehydrogenase
J5J84_16900	COG1921	L-seryl-tRNASec selenium transferase activity
J5J84_16905	COG3276	selenocysteine insertion sequence binding
J5J84_16915	COG1476	TRANSCRIPTIONal
J5J84_16930	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_16950	COG0709	Synthesizes selenophosphate from selenide and ATP
J5J84_16965	COG0583	DNA-binding transcription factor activity
J5J84_16970	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J5J84_16975	COG0348	domain, Protein
J5J84_16975	COG3901	Regulator of nitric oxide reductase transcription
J5J84_16980	COG4263	nitrous-oxide reductase activity
J5J84_16995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J5J84_17010	COG0166	Belongs to the GPI family
J5J84_17055	COG2233	PERMEase
J5J84_17060	COG0697	spore germination
J5J84_17065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_17070	COG0697	spore germination
J5J84_17090	COG2885	chlorophyll binding
J5J84_17185	COG0183	Belongs to the thiolase family
J5J84_17190	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5J84_17190	COG1024	Enoyl-CoA hydratase
J5J84_17205	COG1127	ABC transporter
J5J84_17210	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5J84_17215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J5J84_17230	COG1131	(ABC) transporter
J5J84_17235	COG0842	Transport permease protein
J5J84_17245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5J84_17255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5J84_17260	COG0131	Imidazoleglycerol-phosphate dehydratase
J5J84_17270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5J84_17275	COG0107	imidazoleglycerol-phosphate synthase activity
J5J84_17285	COG0140	phosphoribosyl-ATP diphosphatase activity
J5J84_17290	COG0537	adenosine 5'-monophosphoramidase activity
J5J84_17295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5J84_17300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5J84_17310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5J84_17320	COG1970	mechanosensitive ion channel activity
J5J84_17325	COG0723	plastoquinol--plastocyanin reductase activity
J5J84_17330	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J5J84_17335	COG2857	Cytochrome c1
J5J84_17340	COG0625	glutathione transferase activity
J5J84_17345	COG2969	positive regulation of protein catabolic process
J5J84_17350	COG4208	sulfate ABC transporter
J5J84_17355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5J84_17360	COG4150	thiosulfate binding
J5J84_17380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5J84_17400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5J84_17405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5J84_17415	COG2084	Dehydrogenase
J5J84_17420	COG0129	dihydroxy-acid dehydratase activity
J5J84_17425	COG1802	Transcriptional regulator
J5J84_17430	COG1522	sequence-specific DNA binding
J5J84_17440	COG3483	tryptophan 2,3-dioxygenase activity
J5J84_17460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5J84_17465	COG0656	L-ascorbic acid biosynthetic process
J5J84_17475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5J84_17480	COG3706	GGDEF domain
J5J84_17485	COG2226	methyltransferase
J5J84_17495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5J84_17510	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
J5J84_17515	COG0583	DNA-binding transcription factor activity
J5J84_17520	COG0477	Major facilitator Superfamily
J5J84_17525	COG1028	Short-chain dehydrogenase reductase Sdr
J5J84_17535	COG1335	isochorismatase
J5J84_17555	COG2823	Periplasmic or secreted lipoprotein
J5J84_17565	COG3284	Transcriptional regulator
J5J84_17595	COG1595	DNA-templated transcription, initiation
J5J84_17605	COG1522	sequence-specific DNA binding
J5J84_17615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5J84_17635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5J84_17670	COG0109	protoheme IX farnesyltransferase activity
J5J84_17690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5J84_17710	COG3568	Endonuclease Exonuclease Phosphatase
J5J84_17715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5J84_17740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5J84_17750	COG1228	amidohydrolase
J5J84_17770	COG2986	histidine ammonia-lyase
J5J84_17775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J5J84_17805	COG2814	Major facilitator Superfamily
J5J84_17815	COG0789	Transcriptional regulator
J5J84_17845	COG0625	glutathione transferase activity
J5J84_17875	COG2365	Tyrosine phosphatase family
J5J84_17880	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5J84_17900	COG2423	ornithine cyclodeaminase activity
J5J84_17950	COG3069	C4-dicarboxylate transmembrane transporter activity
J5J84_17960	COG1802	Transcriptional regulator
J5J84_17970	COG2814	Major facilitator Superfamily
J5J84_17985	COG2814	Major facilitator Superfamily
J5J84_17990	COG0251	oxidation-reduction process
J5J84_17995	COG3181	Tripartite tricarboxylate transporter family receptor
J5J84_18000	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5J84_18005	COG2186	Transcriptional regulator
J5J84_18015	COG2814	Major facilitator Superfamily
J5J84_18025	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5J84_18030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5J84_18035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5J84_18055	COG5001	Diguanylate cyclase
J5J84_18055	COG5002	protein histidine kinase activity
J5J84_18065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5J84_18070	COG1333	cytochrome c biogenesis protein
J5J84_18080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J5J84_18085	COG0113	porphobilinogen synthase activity
J5J84_18090	COG4232	protein-disulfide reductase activity
J5J84_18110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5J84_18115	COG0203	ribosomal protein L17
J5J84_18120	COG0202	RNA polymerase activity
J5J84_18125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5J84_18130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5J84_18135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5J84_18140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5J84_18150	COG0201	protein transport
J5J84_18155	COG0200	Binds to the 23S rRNA
J5J84_18160	COG1841	ribosomal large subunit assembly
J5J84_18165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5J84_18170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5J84_18175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5J84_18180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J5J84_18185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5J84_18190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J5J84_18195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5J84_18200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5J84_18240	COG1538	Outer membrane efflux protein
J5J84_18255	COG1960	acyl-CoA dehydrogenase activity
J5J84_18260	COG0183	Belongs to the thiolase family
J5J84_18270	COG2067	long-chain fatty acid transport protein
J5J84_18285	COG0318	PFAM AMP-dependent synthetase and ligase
J5J84_18290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5J84_18295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5J84_18300	COG1648	precorrin-2 dehydrogenase activity
J5J84_18300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5J84_18315	COG1116	anion transmembrane transporter activity
J5J84_18335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5J84_18340	COG0255	Belongs to the universal ribosomal protein uL29 family
J5J84_18345	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5J84_18350	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5J84_18355	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5J84_18360	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5J84_18365	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5J84_18370	COG0089	rRNA binding
J5J84_18375	COG0088	Forms part of the polypeptide exit tunnel
J5J84_18380	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5J84_18385	COG4175	Glycine betaine
J5J84_18390	COG4176	ABC-type proline glycine betaine transport system permease component
J5J84_18395	COG0051	transcription antitermination factor activity, RNA binding
J5J84_18400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5J84_18405	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5J84_18410	COG0049	tRNA binding
J5J84_18415	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5J84_18445	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J5J84_18450	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5J84_18455	COG0085	RNA polymerase activity
J5J84_18460	COG0222	ribosome binding
J5J84_18465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5J84_18470	COG0081	regulation of translation
J5J84_18495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5J84_18515	COG1475	DNA binding
J5J84_18520	COG1192	Involved in chromosome partitioning
J5J84_18525	COG0357	Ribosomal RNA small subunit methyltransferase G
J5J84_18530	COG0445	tRNA wobble uridine modification
J5J84_18535	COG0436	Aminotransferase
J5J84_18545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J5J84_18555	COG3706	GGDEF domain
J5J84_18560	COG0688	phosphatidylethanolamine metabolic process
J5J84_18570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5J84_18615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5J84_18650	COG0753	catalase activity
J5J84_18655	COG0706	membrane insertase activity
J5J84_18660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5J84_18665	COG0594	ribonuclease P activity
J5J84_18670	COG0230	Belongs to the bacterial ribosomal protein bL34 family