locus-tag	class	description
OKX01_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OKX01_00010	COG0592	DNA-directed DNA polymerase activity
OKX01_00045	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_00050	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_00065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OKX01_00080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_00100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OKX01_00105	COG0583	DNA-binding transcription factor activity
OKX01_00115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OKX01_00125	COG0559	Belongs to the binding-protein-dependent transport system permease family
OKX01_00145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OKX01_00155	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_00165	COG0697	spore germination
OKX01_00180	COG3842	ATPase activity
OKX01_00190	COG0436	Aminotransferase
OKX01_00200	COG0523	cobalamin synthesis protein
OKX01_00260	COG1846	Transcriptional regulator
OKX01_00280	COG0179	Fumarylacetoacetate (FAA) hydrolase
OKX01_00285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OKX01_00290	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OKX01_00300	COG4638	Rieske (2fe-2S)
OKX01_00355	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_00380	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OKX01_00395	COG4608	Belongs to the ABC transporter superfamily
OKX01_00400	COG0444	Belongs to the ABC transporter superfamily
OKX01_00405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKX01_00410	COG0601	transmembrane transport
OKX01_00420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OKX01_00425	COG1595	DNA-templated transcription, initiation
OKX01_00430	COG3712	iron ion homeostasis
OKX01_00435	COG4774	siderophore transport
OKX01_00440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OKX01_00445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OKX01_00480	COG4149	molybdate abc transporter
OKX01_00490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OKX01_00495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OKX01_00505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_00525	COG0028	Belongs to the TPP enzyme family
OKX01_00530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_00565	COG2922	Belongs to the Smg family
OKX01_00580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OKX01_00585	COG0183	Belongs to the thiolase family
OKX01_00590	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OKX01_00595	COG1960	acyl-CoA dehydrogenase activity
OKX01_00615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OKX01_00625	COG0018	arginyl-trna synthetase
OKX01_00650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OKX01_00660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OKX01_00665	COG4774	siderophore transport
OKX01_00670	COG0066	3-isopropylmalate dehydratase activity
OKX01_00675	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OKX01_00680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OKX01_00685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OKX01_00690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_00690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OKX01_00700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_00710	COG0583	DNA-binding transcription factor activity
OKX01_00730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OKX01_00735	COG1280	lysine exporter protein (LysE YggA)
OKX01_00740	COG0513	Belongs to the DEAD box helicase family
OKX01_00750	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OKX01_00765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OKX01_00820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OKX01_00825	COG1127	ABC transporter
OKX01_00845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OKX01_00850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_00860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_00895	COG0583	DNA-binding transcription factor activity
OKX01_00920	COG1254	Belongs to the acylphosphatase family
OKX01_00930	COG2358	TRAP transporter, solute receptor (TAXI family
OKX01_00940	COG0564	pseudouridine synthase activity
OKX01_00945	COG0252	asparaginase activity
OKX01_00970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OKX01_00975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OKX01_00980	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_01000	COG0559	Belongs to the binding-protein-dependent transport system permease family
OKX01_01025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OKX01_01040	COG0758	DNA mediated transformation
OKX01_01045	COG0242	peptide deformylase activity
OKX01_01050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OKX01_01055	COG0697	spore germination
OKX01_01070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_01085	COG4336	lyase activity
OKX01_01090	COG0583	DNA-binding transcription factor activity
OKX01_01095	COG0859	PFAM glycosyl transferase family 9
OKX01_01105	COG1278	Cold shock
OKX01_01110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OKX01_01115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OKX01_01120	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OKX01_01120	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OKX01_01130	COG1686	Belongs to the peptidase S11 family
OKX01_01140	COG2921	Belongs to the UPF0250 family
OKX01_01145	COG0321	lipoyl(octanoyl) transferase activity
OKX01_01165	COG1024	Enoyl-CoA hydratase
OKX01_01170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OKX01_01180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OKX01_01225	COG0826	peptidase U32
OKX01_01235	COG3154	lipid carrier protein
OKX01_01260	COG0134	indole-3-glycerol-phosphate synthase activity
OKX01_01265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OKX01_01270	COG0512	Glutamine amidotransferase of anthranilate synthase
OKX01_01280	COG0546	phosphoglycolate phosphatase activity
OKX01_01290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OKX01_01295	COG2967	ApaG domain
OKX01_01305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OKX01_01310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OKX01_01320	COG0840	transmembrane signaling receptor activity
OKX01_01330	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_01335	COG3433	isochorismatase activity
OKX01_01335	COG1535	isochorismatase
OKX01_01340	COG1169	isochorismate synthase
OKX01_01355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OKX01_01360	COG3433	isochorismatase activity
OKX01_01360	COG1535	isochorismatase
OKX01_01365	COG1021	2,3-dihydroxybenzoate-AMP ligase
OKX01_01380	COG0411	ABC transporter
OKX01_01395	COG0683	leucine binding
OKX01_01410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OKX01_01445	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OKX01_01450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKX01_01455	COG2819	hydrolase of the alpha beta superfamily
OKX01_01460	COG0513	Belongs to the DEAD box helicase family
OKX01_01465	COG2814	Major facilitator Superfamily
OKX01_01485	COG1253	flavin adenine dinucleotide binding
OKX01_01515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OKX01_01520	COG2311	Membrane
OKX01_01545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OKX01_01565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OKX01_01570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OKX01_01580	COG0583	DNA-binding transcription factor activity
OKX01_01585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OKX01_01590	COG1126	abc transporter atp-binding protein
OKX01_01595	COG0765	amino acid transport
OKX01_01600	COG0765	amino acid transport
OKX01_01605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OKX01_01610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OKX01_01625	COG3391	amine dehydrogenase activity
OKX01_01635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OKX01_01660	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OKX01_01665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OKX01_01670	COG0210	DNA helicase
OKX01_01690	COG0069	glutamate synthase activity
OKX01_01690	COG0070	glutamate synthase
OKX01_01690	COG0067	glutamate synthase
OKX01_01695	COG1024	Enoyl-CoA hydratase
OKX01_01705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OKX01_01710	COG1250	3-hydroxyacyl-CoA dehydrogenase
OKX01_01735	COG2918	glutathione biosynthetic process
OKX01_01745	COG2197	response regulator
OKX01_01750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OKX01_01760	COG2223	nitrite transmembrane transporter activity
OKX01_01765	COG2860	membrane
OKX01_01770	COG1346	cytolysis
OKX01_01785	COG0251	oxidation-reduction process
OKX01_01800	COG0745	RESPONSE REGULATOR receiver
OKX01_01815	COG1280	lysine exporter protein (LysE YggA)
OKX01_01820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OKX01_01835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OKX01_01850	COG2096	Adenosyltransferase
OKX01_01865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OKX01_01870	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OKX01_01880	COG0523	cobalamin synthesis protein
OKX01_01885	COG0735	belongs to the Fur family
OKX01_01900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OKX01_01905	COG0803	Belongs to the bacterial solute-binding protein 9 family
OKX01_01910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OKX01_01920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OKX01_01925	COG1560	Kdo2-lipid A biosynthetic process
OKX01_01935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OKX01_01940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OKX01_01945	COG1950	PFAM Membrane protein of
OKX01_01980	COG0275	rRNA processing
OKX01_01985	COG0730	response to heat
OKX01_01990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OKX01_01995	COG0129	dihydroxy-acid dehydratase activity
OKX01_02010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OKX01_02030	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_02040	COG0628	permease
OKX01_02050	COG0582	viral genome integration into host DNA
OKX01_02110	COG2003	Belongs to the UPF0758 family
OKX01_02125	COG3620	sequence-specific DNA binding
OKX01_02205	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_02210	COG1846	Transcriptional regulator
OKX01_02225	COG0277	FAD linked oxidase domain protein
OKX01_02230	COG1304	FMN binding
OKX01_02235	COG2186	Transcriptional regulator
OKX01_02250	COG2188	Transcriptional regulator
OKX01_02255	COG1522	sequence-specific DNA binding
OKX01_02265	COG1113	amino acid transport
OKX01_02270	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OKX01_02275	COG1349	DNA-binding transcription factor activity
OKX01_02295	COG0395	ABC-type sugar transport system, permease component
OKX01_02310	COG0861	Integral membrane protein TerC family
OKX01_02325	COG1671	Belongs to the UPF0178 family
OKX01_02335	COG1418	mRNA catabolic process
OKX01_02345	COG4948	Mandelate Racemase Muconate Lactonizing
OKX01_02355	COG0477	Major facilitator Superfamily
OKX01_02370	COG0154	amidase activity
OKX01_02380	COG0583	DNA-binding transcription factor activity
OKX01_02405	COG0326	Molecular chaperone. Has ATPase activity
OKX01_02410	COG4774	siderophore transport
OKX01_02415	COG3128	pkhd-type hydroxylase
OKX01_02440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OKX01_02445	COG1652	LysM domain
OKX01_02460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OKX01_02475	COG1335	isochorismatase
OKX01_02500	COG0583	DNA-binding transcription factor activity
OKX01_02505	COG0387	Pfam Sodium calcium exchanger
OKX01_02520	COG0477	Major facilitator Superfamily
OKX01_02525	COG0235	Class ii aldolase
OKX01_02535	COG3391	amine dehydrogenase activity
OKX01_02540	COG0590	tRNA wobble adenosine to inosine editing
OKX01_02545	COG3257	ureidoglycine aminohydrolase activity
OKX01_02555	COG0583	DNA-binding transcription factor activity
OKX01_02560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKX01_02565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OKX01_02565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OKX01_02575	COG0489	protein tyrosine kinase activity
OKX01_02600	COG2081	HI0933 family
OKX01_02605	COG0509	glycine decarboxylation via glycine cleavage system
OKX01_02615	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OKX01_02620	COG1765	OsmC-like protein
OKX01_02625	COG3278	Belongs to the heme-copper respiratory oxidase family
OKX01_02650	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
OKX01_02655	COG0469	pyruvate kinase activity
OKX01_02660	COG3193	protein, possibly involved in utilization of glycolate and propanediol
OKX01_02670	COG2084	Dehydrogenase
OKX01_02675	COG3622	Belongs to the hyi family
OKX01_02680	COG3960	tartronate-semialdehyde synthase activity
OKX01_02685	COG0583	DNA-binding transcription factor activity
OKX01_02695	COG2233	PERMEase
OKX01_02700	COG1942	4-Oxalocrotonate Tautomerase
OKX01_02705	COG0235	Class ii aldolase
OKX01_02715	COG3648	Uricase
OKX01_02715	COG3195	allantoin biosynthetic process
OKX01_02725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OKX01_02730	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OKX01_02745	COG0438	transferase activity, transferring glycosyl groups
OKX01_02755	COG0438	transferase activity, transferring glycosyl groups
OKX01_02765	COG0277	FAD linked oxidase domain protein
OKX01_02775	COG0179	Fumarylacetoacetate (FAA) hydrolase
OKX01_02780	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OKX01_02790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OKX01_02800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OKX01_02810	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OKX01_02825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OKX01_02830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OKX01_02835	COG0193	aminoacyl-tRNA hydrolase activity
OKX01_02845	COG0012	GTP binding
OKX01_02870	COG1024	Enoyl-CoA hydratase
OKX01_02875	COG0367	asparagine synthase
OKX01_02915	COG0288	reversible hydration of carbon dioxide
OKX01_02920	COG0583	DNA-binding transcription factor activity
OKX01_02950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OKX01_02960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OKX01_02965	COG3088	subunit of a heme lyase
OKX01_02970	COG4235	cytochrome complex assembly
OKX01_02975	COG0785	Cytochrome C biogenesis protein
OKX01_02985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OKX01_02985	COG2169	Transcriptional regulator
OKX01_03005	COG0559	Belongs to the binding-protein-dependent transport system permease family
OKX01_03015	COG0411	ABC transporter
OKX01_03025	COG1858	cytochrome C peroxidase
OKX01_03030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OKX01_03035	COG1959	2 iron, 2 sulfur cluster binding
OKX01_03040	COG2346	COG2346, Truncated hemoglobins
OKX01_03045	COG0463	Glycosyl transferase, family 2
OKX01_03085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OKX01_03090	COG3383	formate dehydrogenase (NAD+) activity
OKX01_03110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OKX01_03130	COG0303	'Molybdopterin
OKX01_03135	COG0521	Mo-molybdopterin cofactor biosynthetic process
OKX01_03140	COG0314	molybdopterin synthase activity
OKX01_03150	COG0315	cyclic pyranopterin monophosphate synthase activity
OKX01_03180	COG0678	peroxiredoxin activity
OKX01_03190	COG0697	spore germination
OKX01_03195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OKX01_03215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OKX01_03260	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OKX01_03265	COG4535	Mg2 and Co2 transporter CorC
OKX01_03270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OKX01_03275	COG1702	phosphate starvation-inducible protein PhoH
OKX01_03280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OKX01_03295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OKX01_03300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OKX01_03305	COG1862	Preprotein translocase
OKX01_03310	COG0343	queuine tRNA-ribosyltransferase activity
OKX01_03315	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OKX01_03320	COG2027	D-alanyl-D-alanine carboxypeptidase
OKX01_03325	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OKX01_03335	COG4575	ribosome binding
OKX01_03350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OKX01_03360	COG0436	Aminotransferase
OKX01_03370	COG0280	phosphate acetyltransferase
OKX01_03370	COG0281	malic enzyme
OKX01_03380	COG2732	(Barnase) inhibitor
OKX01_03385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OKX01_03390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OKX01_03395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OKX01_03400	COG0126	phosphoglycerate kinase activity
OKX01_03425	COG0521	Mo-molybdopterin cofactor biosynthetic process
OKX01_03435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OKX01_03440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OKX01_03445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OKX01_03450	COG0009	L-threonylcarbamoyladenylate synthase
OKX01_03455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OKX01_03460	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_03460	COG2030	dehydratase
OKX01_03465	COG1960	acyl-CoA dehydrogenase activity
OKX01_03475	COG0405	Gamma-glutamyltransferase
OKX01_03485	COG0579	oxidoreductase
OKX01_03490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OKX01_03495	COG0259	pyridoxamine-phosphate oxidase activity
OKX01_03505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OKX01_03520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OKX01_03530	COG1215	transferase activity, transferring glycosyl groups
OKX01_03540	COG0488	(ABC) transporter
OKX01_03560	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OKX01_03565	COG2894	cell division
OKX01_03575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OKX01_03585	COG1294	oxidase, subunit
OKX01_03590	COG0038	chloride channel
OKX01_03600	COG0514	ATP-dependent DNA helicase (RecQ)
OKX01_03605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKX01_03610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKX01_03615	COG0633	Ferredoxin
OKX01_03620	COG0488	(ABC) transporter
OKX01_03630	COG2001	Belongs to the MraZ family
OKX01_03635	COG0275	rRNA processing
OKX01_03640	COG3116	cell division
OKX01_03650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OKX01_03655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OKX01_03660	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OKX01_03670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OKX01_03675	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OKX01_03680	COG1181	Belongs to the D-alanine--D-alanine ligase family
OKX01_03685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OKX01_03700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OKX01_03710	COG0739	heme binding
OKX01_03710	COG1196	nuclear chromosome segregation
OKX01_03710	COG0741	lytic transglycosylase activity
OKX01_03715	COG0653	protein targeting
OKX01_03725	COG2239	Acts as a magnesium transporter
OKX01_03735	COG1473	amidohydrolase
OKX01_03740	COG0318	PFAM AMP-dependent synthetase and ligase
OKX01_03750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OKX01_03750	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OKX01_03765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OKX01_03770	COG2011	ABC-type metal ion transport system permease component
OKX01_03780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OKX01_03785	COG0765	amino acid transport
OKX01_03790	COG1126	abc transporter atp-binding protein
OKX01_03800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OKX01_03815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OKX01_03820	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OKX01_03825	COG0700	Nucleoside recognition
OKX01_03840	COG0204	Acyl-transferase
OKX01_03845	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OKX01_03850	COG0751	glycine-tRNA ligase activity
OKX01_03855	COG0752	glycyl-tRNA synthetase alpha subunit
OKX01_03870	COG1309	transcriptional regulator
OKX01_03880	COG2814	Major facilitator Superfamily
OKX01_03890	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OKX01_03895	COG0617	tRNA 3'-terminal CCA addition
OKX01_03905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OKX01_03910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OKX01_03915	COG1953	Uracil, thiamine, allantoin
OKX01_03920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OKX01_03925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OKX01_03930	COG0586	Pfam SNARE associated Golgi protein
OKX01_03935	COG1477	protein flavinylation
OKX01_03955	COG0860	N-Acetylmuramoyl-L-alanine amidase
OKX01_03960	COG0802	atpase or kinase
OKX01_03970	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_03975	COG0280	phosphate acetyltransferase
OKX01_03975	COG0281	malic enzyme
OKX01_03980	COG0583	DNA-binding transcription factor activity
OKX01_03985	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_03990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OKX01_04010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_04020	COG0582	viral genome integration into host DNA
OKX01_04140	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
OKX01_04155	COG1802	Transcriptional regulator
OKX01_04155	COG4626	Terminase
OKX01_04255	COG3772	lysozyme
OKX01_04275	COG1733	regulation of RNA biosynthetic process
OKX01_04280	COG2910	NAD(P)H-binding
OKX01_04290	COG2223	nitrite transmembrane transporter activity
OKX01_04295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OKX01_04300	COG4974	Belongs to the 'phage' integrase family
OKX01_04305	COG0725	ABC transporter, periplasmic molybdate-binding protein
OKX01_04310	COG4149	molybdate abc transporter
OKX01_04315	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OKX01_04330	COG1074	ATP-dependent DNA helicase activity
OKX01_04365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OKX01_04370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OKX01_04375	COG0505	Belongs to the CarA family
OKX01_04380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OKX01_04395	COG0406	alpha-ribazole phosphatase activity
OKX01_04400	COG2233	PERMEase
OKX01_04405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OKX01_04410	COG1534	Rna-binding protein
OKX01_04415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OKX01_04420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OKX01_04430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OKX01_04440	COG0248	Ppx GppA phosphatase
OKX01_04445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OKX01_04465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OKX01_04470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OKX01_04525	COG1368	sulfuric ester hydrolase activity
OKX01_04555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OKX01_04560	COG3327	negative regulation of DNA-templated transcription, initiation
OKX01_04565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OKX01_04580	COG0009	L-threonylcarbamoyladenylate synthase
OKX01_04585	COG1994	Peptidase M50
OKX01_04590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OKX01_04595	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OKX01_04610	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OKX01_04620	COG0156	8-amino-7-oxononanoate synthase activity
OKX01_04625	COG2124	cytochrome p450
OKX01_04630	COG3135	benzoate transporter
OKX01_04635	COG2850	peptidyl-arginine hydroxylation
OKX01_04640	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OKX01_04645	COG3391	amine dehydrogenase activity
OKX01_04660	COG0577	efflux transmembrane transporter activity
OKX01_04660	COG1136	(ABC) transporter
OKX01_04665	COG1538	Outer membrane efflux protein
OKX01_04670	COG0363	glucosamine-6-phosphate deaminase activity
OKX01_04675	COG1132	(ABC) transporter
OKX01_04685	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_04695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKX01_04705	COG0668	transmembrane transport
OKX01_04750	COG0154	amidase activity
OKX01_04755	COG2031	fatty acid transporter
OKX01_04770	COG0483	inositol monophosphate 1-phosphatase activity
OKX01_04775	COG1253	flavin adenine dinucleotide binding
OKX01_04780	COG1968	undecaprenyl-diphosphatase activity
OKX01_04800	COG0215	cysteine-tRNA ligase activity
OKX01_04810	COG0825	malonyl-CoA metabolic process
OKX01_04815	COG0037	tRNA processing
OKX01_04840	COG0330	HflC and HflK could
OKX01_04855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OKX01_04880	COG4208	sulfate ABC transporter
OKX01_04885	COG3842	ATPase activity
OKX01_04895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OKX01_04925	COG1304	FMN binding
OKX01_04930	COG0435	Glutathione S-transferase
OKX01_04935	COG0655	NAD(P)H dehydrogenase (quinone) activity
OKX01_04950	COG2094	Belongs to the DNA glycosylase MPG family
OKX01_04955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OKX01_04960	COG2363	Small membrane protein
OKX01_04965	COG0598	Magnesium transport protein CorA
OKX01_04970	COG1960	acyl-CoA dehydrogenase activity
OKX01_04975	COG1525	nuclease
OKX01_04980	COG0747	negative chemotaxis
OKX01_04990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKX01_04995	COG4172	Belongs to the ABC transporter superfamily
OKX01_05005	COG3284	Transcriptional regulator
OKX01_05010	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_05015	COG1454	alcohol dehydrogenase
OKX01_05020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OKX01_05045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OKX01_05075	COG3829	transcription factor binding
OKX01_05080	COG0477	Major facilitator Superfamily
OKX01_05090	COG0039	L-malate dehydrogenase activity
OKX01_05095	COG2188	Transcriptional regulator
OKX01_05100	COG2009	succinate dehydrogenase
OKX01_05110	COG1053	succinate dehydrogenase
OKX01_05115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OKX01_05120	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OKX01_05125	COG0372	Belongs to the citrate synthase family
OKX01_05130	COG2186	Transcriptional regulator
OKX01_05135	COG1620	l-lactate permease
OKX01_05140	COG0280	phosphate acetyltransferase
OKX01_05140	COG0281	malic enzyme
OKX01_05145	COG0567	Dehydrogenase, E1 component
OKX01_05150	COG0508	dehydrogenase complex catalyzes the overall conversion of
OKX01_05155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OKX01_05160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OKX01_05180	COG2183	response to ionizing radiation
OKX01_05185	COG1199	ATP-dependent helicase activity
OKX01_05190	COG0659	secondary active sulfate transmembrane transporter activity
OKX01_05200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OKX01_05200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OKX01_05205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_05230	COG0564	pseudouridine synthase activity
OKX01_05240	COG3243	poly(R)-hydroxyalkanoic acid synthase
OKX01_05245	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_05250	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
OKX01_05275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OKX01_05280	COG1187	pseudouridine synthase activity
OKX01_05285	COG0779	Required for maturation of 30S ribosomal subunits
OKX01_05290	COG0195	Participates in both transcription termination and antitermination
OKX01_05290	COG2251	uridine kinase activity
OKX01_05300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OKX01_05305	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OKX01_05310	COG1217	gtp-binding protein TYPA
OKX01_05315	COG0446	pyridine nucleotide-disulphide oxidoreductase
OKX01_05325	COG4160	amino acid transport
OKX01_05330	COG4215	(ABC) transporter
OKX01_05340	COG1611	Belongs to the LOG family
OKX01_05350	COG1283	sodium-dependent phosphate transmembrane transporter activity
OKX01_05355	COG0501	Belongs to the peptidase M48B family
OKX01_05370	COG1722	exodeoxyribonuclease VII activity
OKX01_05375	COG0142	geranyltranstransferase activity
OKX01_05380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OKX01_05385	COG1469	GTP cyclohydrolase I activity
OKX01_05390	COG0360	Binds together with S18 to 16S ribosomal RNA
OKX01_05395	COG2965	DNA replication, synthesis of RNA primer
OKX01_05400	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OKX01_05405	COG0359	binds to the 23S rRNA
OKX01_05410	COG0305	Participates in initiation and elongation during chromosome replication
OKX01_05420	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OKX01_05425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OKX01_05430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OKX01_05440	COG0436	Aminotransferase
OKX01_05460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OKX01_05465	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
OKX01_05470	COG1562	ergosterol biosynthetic process
OKX01_05475	COG1562	ergosterol biosynthetic process
OKX01_05480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OKX01_05485	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_05510	COG3842	ATPase activity
OKX01_05515	COG1176	ABC-type spermidine putrescine transport system, permease component I
OKX01_05520	COG1177	transmembrane transport
OKX01_05525	COG1393	Belongs to the ArsC family
OKX01_05530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OKX01_05535	COG0704	Plays a role in the regulation of phosphate uptake
OKX01_05540	COG2203	Gaf domain
OKX01_05540	COG5001	Diguanylate cyclase
OKX01_05540	COG4251	negative regulation of phosphorylation
OKX01_05540	COG3706	GGDEF domain
OKX01_05545	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OKX01_05550	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OKX01_05550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OKX01_05555	COG1643	Atp-dependent helicase
OKX01_05565	COG0438	transferase activity, transferring glycosyl groups
OKX01_05570	COG0726	polysaccharide deacetylase
OKX01_05585	COG0297	glycogen (starch) synthase activity
OKX01_05610	COG1132	(ABC) transporter
OKX01_05655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OKX01_05675	COG2186	Transcriptional regulator
OKX01_05680	COG0277	FAD linked oxidase domain protein
OKX01_05685	COG0277	FAD linked oxidase domain protein
OKX01_05690	COG0247	lactate metabolic process
OKX01_05720	COG2159	amidohydrolase
OKX01_05735	COG0583	DNA-binding transcription factor activity
OKX01_05740	COG0477	Major facilitator Superfamily
OKX01_05790	COG0628	permease
OKX01_05795	COG1283	sodium-dependent phosphate transmembrane transporter activity
OKX01_05810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OKX01_05820	COG0697	spore germination
OKX01_05840	COG3094	Invasion gene expression up-regulator, SirB
OKX01_05850	COG0640	Transcriptional regulator
OKX01_05875	COG0659	secondary active sulfate transmembrane transporter activity
OKX01_05880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OKX01_05890	COG2314	TM2 domain
OKX01_05895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OKX01_05900	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OKX01_05905	COG0791	NLP P60 protein
OKX01_05925	COG1360	Flagellar Motor Protein
OKX01_05935	COG0835	chemotaxis
OKX01_05940	COG0840	transmembrane signaling receptor activity
OKX01_05945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OKX01_05955	COG0745	RESPONSE REGULATOR receiver
OKX01_05960	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OKX01_05965	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OKX01_05970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OKX01_05980	COG3550	peptidyl-serine autophosphorylation
OKX01_06005	COG1815	bacterial-type flagellum-dependent cell motility
OKX01_06010	COG1558	bacterial-type flagellum-dependent cell motility
OKX01_06015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OKX01_06055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OKX01_06070	COG0840	transmembrane signaling receptor activity
OKX01_06090	COG1987	bacterial-type flagellum assembly
OKX01_06105	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OKX01_06130	COG1157	protein secretion by the type III secretion system
OKX01_06145	COG1766	The M ring may be actively involved in energy transduction
OKX01_06150	COG1677	Flagellar hook-basal body complex protein FliE
OKX01_06155	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OKX01_06180	COG1334	flagellar protein FlaG
OKX01_06185	COG1191	sigma factor activity
OKX01_06190	COG2161	toxin-antitoxin pair type II binding
OKX01_06245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OKX01_06265	COG2733	membrane
OKX01_06270	COG0840	transmembrane signaling receptor activity
OKX01_06275	COG0840	transmembrane signaling receptor activity
OKX01_06300	COG2610	gluconate transmembrane transporter activity
OKX01_06325	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OKX01_06330	COG3657	addiction module killer protein
OKX01_06335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OKX01_06350	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_06360	COG2824	Alkylphosphonate utilization operon protein PhnA
OKX01_06375	COG4771	TonB-dependent receptor
OKX01_06380	COG1858	cytochrome C peroxidase
OKX01_06385	COG1454	alcohol dehydrogenase
OKX01_06410	COG1113	amino acid transport
OKX01_06415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OKX01_06455	COG0446	pyridine nucleotide-disulphide oxidoreductase
OKX01_06480	COG1278	Cold shock
OKX01_06490	COG0642	Histidine kinase
OKX01_06500	COG3278	Belongs to the heme-copper respiratory oxidase family
OKX01_06510	COG2863	cytochrome
OKX01_06515	COG3258	Cytochrome c
OKX01_06520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OKX01_06525	COG4774	siderophore transport
OKX01_06570	COG1289	transmembrane transporter activity
OKX01_06575	COG2252	PERMEase
OKX01_06595	COG1999	signal sequence binding
OKX01_06610	COG0069	glutamate synthase activity
OKX01_06620	COG1846	Transcriptional regulator
OKX01_06625	COG1058	Belongs to the CinA family
OKX01_06625	COG1546	Belongs to the CinA family
OKX01_06630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OKX01_06670	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_06680	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_06695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OKX01_06705	COG1511	domain protein
OKX01_06705	COG3264	Mechanosensitive ion channel
OKX01_06710	COG1511	domain protein
OKX01_06710	COG3264	Mechanosensitive ion channel
OKX01_06715	COG0477	Major facilitator Superfamily
OKX01_06730	COG1396	sequence-specific DNA binding
OKX01_06735	COG3437	response regulator, receiver
OKX01_06740	COG0784	Response regulator, receiver
OKX01_06740	COG2198	Histidine kinase
OKX01_06740	COG2205	protein histidine kinase activity
OKX01_06745	COG2239	Acts as a magnesium transporter
OKX01_06755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OKX01_06760	COG1490	D-aminoacyl-tRNA deacylase activity
OKX01_06775	COG0456	acetyltransferase
OKX01_06780	COG3012	SEC-C Motif Domain Protein
OKX01_06785	COG0501	Belongs to the peptidase M48B family
OKX01_06910	COG0582	viral genome integration into host DNA
OKX01_06920	COG3772	lysozyme
OKX01_06970	COG3706	GGDEF domain
OKX01_06985	COG1522	sequence-specific DNA binding
OKX01_06990	COG0626	cystathionine gamma-synthase activity
OKX01_07000	COG0494	nUDIX hydrolase
OKX01_07005	COG2832	Protein of unknown function (DUF454)
OKX01_07015	COG0137	argininosuccinate synthase activity
OKX01_07020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OKX01_07045	COG1609	Transcriptional regulator
OKX01_07050	COG0519	Catalyzes the synthesis of GMP from XMP
OKX01_07050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OKX01_07060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OKX01_07070	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OKX01_07075	COG2205	protein histidine kinase activity
OKX01_07080	COG0745	RESPONSE REGULATOR receiver
OKX01_07085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OKX01_07095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKX01_07100	COG0268	Binds directly to 16S ribosomal RNA
OKX01_07105	COG0728	peptidoglycan biosynthetic process
OKX01_07115	COG0563	adenylate kinase activity
OKX01_07120	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OKX01_07125	COG2835	tetraacyldisaccharide 4'-kinase activity
OKX01_07130	COG1663	tetraacyldisaccharide 4'-kinase activity
OKX01_07135	COG0848	biopolymer transport protein
OKX01_07140	COG0811	peptide transport
OKX01_07145	COG1570	exodeoxyribonuclease VII activity
OKX01_07150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OKX01_07160	COG0183	Belongs to the thiolase family
OKX01_07170	COG1278	Cold shock
OKX01_07175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OKX01_07180	COG0542	response to heat
OKX01_07185	COG2995	paraquat-inducible protein a
OKX01_07190	COG3008	intermembrane lipid transfer
OKX01_07190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OKX01_07210	COG0559	Belongs to the binding-protein-dependent transport system permease family
OKX01_07275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
OKX01_07280	COG0756	dUTP diphosphatase activity
OKX01_07290	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OKX01_07295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OKX01_07300	COG0196	riboflavin kinase activity
OKX01_07305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OKX01_07310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OKX01_07310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OKX01_07320	COG0210	DNA helicase
OKX01_07345	COG0488	(ABC) transporter
OKX01_07350	COG2890	protein-(glutamine-N5) methyltransferase activity
OKX01_07355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OKX01_07360	COG2171	N-acyltransferase activity
OKX01_07370	COG2207	Transcriptional regulator
OKX01_07380	COG0471	metal ion transport
OKX01_07380	COG3273	potassium ion transport
OKX01_07425	COG0789	Transcriptional regulator
OKX01_07440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OKX01_07445	COG0544	peptidyl-prolyl cis-trans isomerase activity
OKX01_07450	COG0740	serine-type endopeptidase activity
OKX01_07460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OKX01_07470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OKX01_07480	COG0556	nucleotide-excision repair
OKX01_07485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OKX01_07495	COG1104	cysteine desulfurase activity
OKX01_07505	COG0316	Belongs to the HesB IscA family
OKX01_07510	COG1803	Methylglyoxal synthase
OKX01_07510	COG1597	lipid kinase activity
OKX01_07515	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OKX01_07520	COG4221	oxidoreductase activity
OKX01_07530	COG0840	transmembrane signaling receptor activity
OKX01_07535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OKX01_07540	COG0697	spore germination
OKX01_07545	COG0385	Bile acid
OKX01_07555	COG2831	hemolysin activation secretion protein
OKX01_07560	COG3210	domain, Protein
OKX01_07590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OKX01_07605	COG1136	(ABC) transporter
OKX01_07610	COG0084	hydrolase, TatD family'
OKX01_07625	COG0613	PHP domain protein
OKX01_07635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OKX01_07635	COG0047	phosphoribosylformylglycinamidine synthase activity
OKX01_07650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OKX01_07650	COG0519	Catalyzes the synthesis of GMP from XMP
OKX01_07675	COG4691	Plasmid stability protein
OKX01_07705	COG0798	PFAM Bile acid sodium symporter
OKX01_07770	COG1061	Type III restriction enzyme res subunit
OKX01_07790	COG0583	DNA-binding transcription factor activity
OKX01_07805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OKX01_07815	COG1960	acyl-CoA dehydrogenase activity
OKX01_07825	COG2378	regulation of single-species biofilm formation
OKX01_07830	COG0523	cobalamin synthesis protein
OKX01_07835	COG1469	GTP cyclohydrolase I activity
OKX01_07840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OKX01_07850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OKX01_07855	COG0735	belongs to the Fur family
OKX01_07860	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OKX01_07870	COG0494	nUDIX hydrolase
OKX01_07875	COG1942	4-Oxalocrotonate Tautomerase
OKX01_07890	COG2070	2-Nitropropane dioxygenase
OKX01_07935	COG0494	nUDIX hydrolase
OKX01_07940	COG0625	glutathione transferase activity
OKX01_07945	COG0740	serine-type endopeptidase activity
OKX01_07995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OKX01_08005	COG1960	acyl-CoA dehydrogenase activity
OKX01_08025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OKX01_08030	COG0640	Transcriptional regulator
OKX01_08050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OKX01_08065	COG3485	protocatechuate 3,4-dioxygenase
OKX01_08075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OKX01_08080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OKX01_08090	COG3135	benzoate transporter
OKX01_08095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OKX01_08100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OKX01_08115	COG4555	ABC transporter
OKX01_08125	COG2197	response regulator
OKX01_08130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OKX01_08155	COG1846	Transcriptional regulator
OKX01_08160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OKX01_08165	COG2271	Major facilitator Superfamily
OKX01_08175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OKX01_08185	COG0697	spore germination
OKX01_08215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OKX01_08220	COG0667	Aldo Keto reductase
OKX01_08235	COG1272	protein, Hemolysin III
OKX01_08240	COG3422	double-strand break repair
OKX01_08250	COG0477	Major facilitator Superfamily
OKX01_08255	COG0154	amidase activity
OKX01_08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OKX01_08285	COG0765	amino acid transport
OKX01_08290	COG0765	amino acid transport
OKX01_08295	COG1126	abc transporter atp-binding protein
OKX01_08345	COG2871	sodium ion transport
OKX01_08385	COG2814	Major facilitator Superfamily
OKX01_08395	COG1280	lysine exporter protein (LysE YggA)
OKX01_08415	COG0402	S-adenosylhomocysteine deaminase activity
OKX01_08435	COG0330	HflC and HflK could
OKX01_08440	COG1585	Membrane protein implicated in regulation of membrane protease activity
OKX01_08445	COG2226	methyltransferase
OKX01_08455	COG3042	response to heat
OKX01_08465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OKX01_08475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OKX01_08480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OKX01_08495	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OKX01_08500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OKX01_08530	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OKX01_08535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OKX01_08540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OKX01_08545	COG0072	phenylalanine-tRNA ligase activity
OKX01_08545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OKX01_08560	COG2833	Protein of unknown function (DUF455)
OKX01_08570	COG5265	(ABC) transporter
OKX01_08575	COG1959	2 iron, 2 sulfur cluster binding
OKX01_08580	COG0719	Fe-S assembly protein
OKX01_08585	COG0396	ATPase activity
OKX01_08590	COG0719	Fe-S assembly protein
OKX01_08600	COG0822	iron-sulfur transferase activity
OKX01_08605	COG2151	metal-sulfur cluster biosynthetic enzyme
OKX01_08640	COG1215	transferase activity, transferring glycosyl groups
OKX01_08645	COG1649	PFAM Uncharacterised BCR, COG1649
OKX01_08645	COG0726	polysaccharide deacetylase
OKX01_08650	COG0457	Tetratricopeptide repeat
OKX01_08660	COG1278	Cold shock
OKX01_08710	COG0747	negative chemotaxis
OKX01_08715	COG0601	transmembrane transport
OKX01_08720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKX01_08725	COG4172	Belongs to the ABC transporter superfamily
OKX01_08735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OKX01_08855	COG3949	Membrane
OKX01_08865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OKX01_08880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OKX01_08885	COG0569	domain protein
OKX01_08890	COG1902	pentaerythritol trinitrate reductase activity
OKX01_08900	COG1610	YqeY-like protein
OKX01_08905	COG0587	DNA-directed DNA polymerase activity
OKX01_08940	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_08945	COG0583	DNA-binding transcription factor activity
OKX01_08950	COG1686	Belongs to the peptidase S11 family
OKX01_08975	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_08980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKX01_08985	COG4221	oxidoreductase activity
OKX01_08990	COG0307	riboflavin synthase, alpha
OKX01_09005	COG1301	dicarboxylic acid transport
OKX01_09010	COG4191	Histidine kinase
OKX01_09020	COG0583	DNA-binding transcription factor activity
OKX01_09025	COG1053	succinate dehydrogenase
OKX01_09075	COG2233	PERMEase
OKX01_09080	COG0071	Belongs to the small heat shock protein (HSP20) family
OKX01_09120	COG1846	Transcriptional regulator
OKX01_09125	COG2816	NAD+ diphosphatase activity
OKX01_09130	COG1561	YicC-like family, N-terminal region
OKX01_09145	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OKX01_09150	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OKX01_09155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OKX01_09160	COG0174	glutamine synthetase
OKX01_09165	COG2153	protein acetylation
OKX01_09185	COG3842	ATPase activity
OKX01_09190	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OKX01_09195	COG1840	ABC-type Fe3 transport system, periplasmic component
OKX01_09215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OKX01_09225	COG0783	Belongs to the Dps family
OKX01_09235	COG3842	ATPase activity
OKX01_09240	COG0395	ABC-type sugar transport system, permease component
OKX01_09245	COG1175	transmembrane transport
OKX01_09250	COG1653	transport
OKX01_09265	COG0559	Belongs to the binding-protein-dependent transport system permease family
OKX01_09290	COG0625	glutathione transferase activity
OKX01_09300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKX01_09305	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_09310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OKX01_09315	COG0114	fumarate hydratase activity
OKX01_09320	COG2133	pyrroloquinoline quinone binding
OKX01_09325	COG2226	methyltransferase
OKX01_09330	COG0589	response to stress
OKX01_09340	COG2807	transmembrane transport
OKX01_09350	COG0583	DNA-binding transcription factor activity
OKX01_09370	COG4974	Belongs to the 'phage' integrase family
OKX01_09385	COG2132	Multicopper oxidase
OKX01_09390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OKX01_09570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OKX01_09640	COG2003	Belongs to the UPF0758 family
OKX01_09705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OKX01_09750	COG2894	cell division
OKX01_09855	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_09860	COG1683	Conserved Protein
OKX01_09895	COG3038	cytochrome b561
OKX01_09905	COG2353	YceI-like domain
OKX01_09910	COG1393	Belongs to the ArsC family
OKX01_09915	COG0625	glutathione transferase activity
OKX01_09940	COG0084	hydrolase, TatD family'
OKX01_09945	COG0470	DNA polymerase III
OKX01_09955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OKX01_09960	COG0354	folic acid binding
OKX01_09975	COG1960	acyl-CoA dehydrogenase activity
OKX01_09980	COG2914	Belongs to the UPF0125 (RnfH) family
OKX01_09985	COG2867	negative regulation of translational initiation
OKX01_09990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OKX01_09995	COG1252	NADH dehydrogenase
OKX01_10020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OKX01_10025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OKX01_10030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OKX01_10040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OKX01_10045	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OKX01_10055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OKX01_10065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OKX01_10070	COG0575	Belongs to the CDS family
OKX01_10075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OKX01_10080	COG0233	cytoplasmic translational termination
OKX01_10085	COG0528	UMP kinase activity
OKX01_10090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OKX01_10095	COG0052	Belongs to the universal ribosomal protein uS2 family
OKX01_10100	COG0024	Methionine aminopeptidase
OKX01_10105	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OKX01_10130	COG1286	toxin biosynthetic process
OKX01_10140	COG0285	dihydrofolate synthase activity
OKX01_10145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OKX01_10150	COG0508	dehydrogenase complex catalyzes the overall conversion of
OKX01_10155	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OKX01_10170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OKX01_10180	COG1999	signal sequence binding
OKX01_10185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OKX01_10200	COG0640	Transcriptional regulator
OKX01_10215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_10220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OKX01_10225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OKX01_10230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OKX01_10235	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_10260	COG0183	Belongs to the thiolase family
OKX01_10280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OKX01_10290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OKX01_10295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OKX01_10300	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OKX01_10320	COG0183	Belongs to the thiolase family
OKX01_10325	COG0183	Belongs to the thiolase family
OKX01_10335	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OKX01_10370	COG0194	GDP metabolic process
OKX01_10375	COG1758	RNA polymerase activity
OKX01_10380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OKX01_10390	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OKX01_10395	COG0739	heme binding
OKX01_10400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OKX01_10405	COG0584	glycerophosphoryl diester phosphodiesterase
OKX01_10410	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OKX01_10415	COG1187	pseudouridine synthase activity
OKX01_10420	COG3161	chorismate lyase activity
OKX01_10425	COG2814	Major facilitator Superfamily
OKX01_10430	COG0656	L-ascorbic acid biosynthetic process
OKX01_10440	COG0668	transmembrane transport
OKX01_10445	COG0165	Argininosuccinate lyase
OKX01_10460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OKX01_10470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OKX01_10480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OKX01_10485	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OKX01_10490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OKX01_10495	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OKX01_10500	COG2252	PERMEase
OKX01_10505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OKX01_10525	COG0488	(ABC) transporter
OKX01_10530	COG1619	proteins homologs of microcin C7 resistance protein MccF
OKX01_10535	COG0590	tRNA wobble adenosine to inosine editing
OKX01_10540	COG1131	(ABC) transporter
OKX01_10545	COG0842	Transport permease protein
OKX01_10555	COG1666	GTP binding
OKX01_10560	COG0318	PFAM AMP-dependent synthetase and ligase
OKX01_10565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OKX01_10570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OKX01_10570	COG0519	Catalyzes the synthesis of GMP from XMP
OKX01_10575	COG2207	Transcriptional regulator
OKX01_10590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OKX01_10595	COG0135	phosphoribosylanthranilate isomerase activity
OKX01_10600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_10610	COG0101	tRNA pseudouridine synthase activity
OKX01_10620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OKX01_10625	COG0473	3-isopropylmalate dehydrogenase activity
OKX01_10640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OKX01_10650	COG4566	intracellular signal transduction
OKX01_10665	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OKX01_10670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OKX01_10680	COG1295	ribonuclease BN
OKX01_10690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OKX01_10720	COG4964	Belongs to the GSP D family
OKX01_10760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OKX01_10770	COG2959	enzyme of heme biosynthesis
OKX01_10780	COG0181	hydroxymethylbilane synthase activity
OKX01_10790	COG0861	Integral membrane protein TerC family
OKX01_10795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OKX01_10800	COG0045	succinate-CoA ligase (ADP-forming) activity
OKX01_10810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OKX01_10815	COG0583	DNA-binding transcription factor activity
OKX01_10820	COG2137	regulation of response to DNA damage stimulus
OKX01_10825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OKX01_10840	COG0477	Major facilitator Superfamily
OKX01_10855	COG0318	PFAM AMP-dependent synthetase and ligase
OKX01_10860	COG1024	Enoyl-CoA hydratase
OKX01_10865	COG3162	membrane
OKX01_10880	COG0540	Belongs to the ATCase OTCase family
OKX01_10895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OKX01_10910	COG2070	2-Nitropropane dioxygenase
OKX01_10915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OKX01_10920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OKX01_10920	COG2111	Na H antiporter
OKX01_10925	COG1006	Multisubunit Na H antiporter MnhC subunit
OKX01_10930	COG0651	ATP synthesis coupled electron transport
OKX01_10940	COG2212	antiporter activity
OKX01_10955	COG3158	transport of potassium into the cell
OKX01_10960	COG0642	Histidine kinase
OKX01_10985	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OKX01_10990	COG4208	sulfate ABC transporter
OKX01_10995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OKX01_11000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OKX01_11005	COG2890	protein-(glutamine-N5) methyltransferase activity
OKX01_11015	COG1278	Cold shock
OKX01_11035	COG1648	precorrin-2 dehydrogenase activity
OKX01_11035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OKX01_11040	COG2010	Cytochrome c
OKX01_11050	COG1522	sequence-specific DNA binding
OKX01_11065	COG0535	radical SAM domain protein
OKX01_11075	COG1648	precorrin-2 dehydrogenase activity
OKX01_11075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OKX01_11085	COG2010	Cytochrome c
OKX01_11090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OKX01_11100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OKX01_11105	COG0557	exoribonuclease II activity
OKX01_11135	COG2375	cellular response to nickel ion
OKX01_11165	COG0583	DNA-binding transcription factor activity
OKX01_11170	COG3842	ATPase activity
OKX01_11180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OKX01_11185	COG1840	ABC-type Fe3 transport system, periplasmic component
OKX01_11210	COG3530	Putative quorum-sensing-regulated virulence factor
OKX01_11215	COG0625	glutathione transferase activity
OKX01_11225	COG1741	Belongs to the pirin family
OKX01_11235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OKX01_11240	COG2814	Major facilitator Superfamily
OKX01_11245	COG2807	transmembrane transport
OKX01_11250	COG2207	Transcriptional regulator
OKX01_11255	COG3135	benzoate transporter
OKX01_11280	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OKX01_11290	COG0402	S-adenosylhomocysteine deaminase activity
OKX01_11300	COG0745	RESPONSE REGULATOR receiver
OKX01_11305	COG2205	protein histidine kinase activity
OKX01_11320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OKX01_11325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OKX01_11330	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OKX01_11335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OKX01_11340	COG0330	HflC and HflK could
OKX01_11345	COG0330	HflC and HflK could
OKX01_11350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OKX01_11355	COG1923	regulation of RNA biosynthetic process
OKX01_11365	COG1160	GTP binding
OKX01_11370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OKX01_11375	COG2976	Protein conserved in bacteria
OKX01_11395	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OKX01_11400	COG0105	UTP biosynthetic process
OKX01_11415	COG0336	Belongs to the RNA methyltransferase TrmD family
OKX01_11425	COG0228	four-way junction DNA binding
OKX01_11430	COG0425	Belongs to the sulfur carrier protein TusA family
OKX01_11435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OKX01_11450	COG2351	hydroxyisourate hydrolase activity
OKX01_11485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OKX01_11510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OKX01_11515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OKX01_11530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OKX01_11535	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OKX01_11540	COG0542	response to heat
OKX01_11545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OKX01_11560	COG0348	domain, Protein
OKX01_11580	COG3278	Belongs to the heme-copper respiratory oxidase family
OKX01_11590	COG2217	Heavy metal translocating P-type atpase
OKX01_11595	COG2224	Isocitrate lyase
OKX01_11600	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OKX01_11600	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OKX01_11620	COG1472	Belongs to the glycosyl hydrolase 3 family
OKX01_11625	COG0736	holo-[acyl-carrier-protein] synthase activity
OKX01_11635	COG2050	protein possibly involved in aromatic compounds catabolism
OKX01_11640	COG1024	Enoyl-CoA hydratase
OKX01_11645	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_11650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OKX01_11655	COG2151	metal-sulfur cluster biosynthetic enzyme
OKX01_11660	COG3396	Phenylacetate-CoA oxygenase
OKX01_11665	COG3460	Phenylacetate-CoA oxygenase
OKX01_11670	COG3396	Phenylacetate-CoA oxygenase
OKX01_11675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OKX01_11680	COG0501	Belongs to the peptidase M48B family
OKX01_11685	COG1162	GTPase activity
OKX01_11695	COG0335	large ribosomal subunit rRNA binding
OKX01_11705	COG0095	Lipoate-protein ligase
OKX01_11715	COG0450	alkyl hydroperoxide reductase
OKX01_11720	COG1960	acyl-CoA dehydrogenase activity
OKX01_11735	COG0123	including yeast histone deacetylase and acetoin utilization protein
OKX01_11740	COG2951	lytic endotransglycosylase activity
OKX01_11755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OKX01_11760	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OKX01_11765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OKX01_11785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OKX01_11790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OKX01_11795	COG0287	Prephenate dehydrogenase
OKX01_11805	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OKX01_11820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OKX01_11840	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OKX01_11850	COG4771	TonB-dependent receptor
OKX01_11865	COG0753	catalase activity
OKX01_11875	COG4335	DNA alkylation repair
OKX01_11880	COG1846	Transcriptional regulator
OKX01_11885	COG0436	Aminotransferase
OKX01_11895	COG0251	oxidation-reduction process
OKX01_11900	COG1309	transcriptional regulator
OKX01_11935	COG0625	glutathione transferase activity
OKX01_11945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OKX01_11950	COG1280	lysine exporter protein (LysE YggA)
OKX01_11975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OKX01_11985	COG5002	protein histidine kinase activity
OKX01_11995	COG2046	Belongs to the sulfate adenylyltransferase family
OKX01_12000	COG2814	Major facilitator Superfamily
OKX01_12010	COG0583	DNA-binding transcription factor activity
OKX01_12015	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OKX01_12030	COG0840	transmembrane signaling receptor activity
OKX01_12035	COG2119	membrane
OKX01_12050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OKX01_12060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OKX01_12075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OKX01_12080	COG2321	neutral zinc metallopeptidase
OKX01_12095	COG0347	Belongs to the P(II) protein family
OKX01_12100	COG0004	ammonium transporteR
OKX01_12105	COG3909	cytochrome
OKX01_12115	COG0625	glutathione transferase activity
OKX01_12125	COG0657	acetylesterase activity
OKX01_12130	COG0730	response to heat
OKX01_12135	COG0482	sulfurtransferase activity
OKX01_12140	COG0277	FAD linked oxidase domain protein
OKX01_12145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OKX01_12150	COG2879	small protein
OKX01_12155	COG1966	Carbon starvation protein
OKX01_12160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OKX01_12165	COG0765	amino acid transport
OKX01_12170	COG0765	amino acid transport
OKX01_12175	COG1126	abc transporter atp-binding protein
OKX01_12185	COG5285	phytanoyl-CoA dioxygenase
OKX01_12190	COG0662	Cupin 2, conserved barrel domain protein
OKX01_12200	COG0456	acetyltransferase
OKX01_12205	COG1846	Transcriptional regulator
OKX01_12215	COG0312	modulator of DNA gyrase
OKX01_12230	COG0308	aminopeptidase N
OKX01_12235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OKX01_12260	COG0473	3-isopropylmalate dehydrogenase activity
OKX01_12270	COG0433	COG0433 Predicted ATPase
OKX01_12275	COG0217	transcriptional regulatory protein
OKX01_12280	COG0151	Belongs to the GarS family
OKX01_12290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OKX01_12295	COG0799	negative regulation of ribosome biogenesis
OKX01_12300	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OKX01_12305	COG0424	maF-like protein
OKX01_12325	COG0023	Translation Initiation Factor
OKX01_12335	COG2084	Dehydrogenase
OKX01_12340	COG0625	glutathione transferase activity
OKX01_12345	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OKX01_12350	COG1047	Peptidyl-prolyl cis-trans
OKX01_12355	COG2003	Belongs to the UPF0758 family
OKX01_12360	COG1737	Transcriptional regulator
OKX01_12365	COG0477	Major facilitator Superfamily
OKX01_12375	COG2271	Major facilitator Superfamily
OKX01_12390	COG0534	Mate efflux family protein
OKX01_12395	COG4175	Glycine betaine
OKX01_12400	COG4176	ABC-type proline glycine betaine transport system permease component
OKX01_12410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OKX01_12415	COG2814	Major facilitator Superfamily
OKX01_12420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OKX01_12425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OKX01_12430	COG0495	leucyl-tRNA aminoacylation
OKX01_12440	COG1466	dna polymerase III delta subunit
OKX01_12445	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OKX01_12450	COG1981	membrane
OKX01_12465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OKX01_12475	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OKX01_12480	COG0148	phosphopyruvate hydratase activity
OKX01_12490	COG2814	Major facilitator Superfamily
OKX01_12505	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OKX01_12510	COG0504	CTP synthase activity
OKX01_12545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OKX01_12555	COG0791	NLP P60 protein
OKX01_12565	COG0583	DNA-binding transcription factor activity
OKX01_12575	COG0583	DNA-binding transcription factor activity
OKX01_12580	COG4774	siderophore transport
OKX01_12590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKX01_12600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKX01_12605	COG1309	transcriptional regulator
OKX01_12615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OKX01_12630	COG1045	serine acetyltransferase
OKX01_12645	COG1381	Involved in DNA repair and RecF pathway recombination
OKX01_12650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OKX01_12655	COG0571	ribonuclease III activity
OKX01_12670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OKX01_12690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OKX01_12695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OKX01_12700	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_12705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OKX01_12710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OKX01_12720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OKX01_12725	COG1399	metal-binding, possibly nucleic acid-binding protein
OKX01_12730	COG0424	maF-like protein
OKX01_12740	COG3023	N-Acetylmuramoyl-L-alanine amidase
OKX01_12745	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OKX01_12750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OKX01_12755	COG0546	phosphoglycolate phosphatase activity
OKX01_12760	COG0564	pseudouridine synthase activity
OKX01_12765	COG1530	ribonuclease E activity
OKX01_12775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OKX01_12780	COG0159	tryptophan synthase activity
OKX01_12785	COG0133	tryptophan synthase activity
OKX01_12790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OKX01_12800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OKX01_12805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OKX01_12815	COG2878	Part of a membrane complex involved in electron transport
OKX01_12820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OKX01_12830	COG3047	cAMP biosynthetic process
OKX01_12855	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OKX01_12860	COG2917	probably involved in intracellular septation
OKX01_12870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OKX01_12875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OKX01_12885	COG1196	nuclear chromosome segregation
OKX01_12895	COG1573	uracil-dna glycosylase
OKX01_12900	COG1214	PFAM Peptidase M22, glycoprotease
OKX01_12915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OKX01_12920	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OKX01_12925	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OKX01_12930	COG0560	Phosphoserine phosphatase
OKX01_12945	COG1007	ATP synthesis coupled electron transport
OKX01_12960	COG0713	ATP synthesis coupled electron transport
OKX01_12970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OKX01_12975	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OKX01_12980	COG1034	ATP synthesis coupled electron transport
OKX01_12995	COG0649	NAD binding
OKX01_13000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OKX01_13005	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OKX01_13010	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OKX01_13015	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OKX01_13030	COG0149	triose-phosphate isomerase activity
OKX01_13035	COG0604	alcohol dehydrogenase
OKX01_13050	COG1185	polyribonucleotide nucleotidyltransferase activity
OKX01_13055	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OKX01_13060	COG1183	phosphatidylcholine synthase activity
OKX01_13065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OKX01_13070	COG0440	acetolactate synthase activity
OKX01_13075	COG0028	Belongs to the TPP enzyme family
OKX01_13080	COG1289	transmembrane transporter activity
OKX01_13085	COG3022	response to hydroperoxide
OKX01_13090	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_13115	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OKX01_13120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OKX01_13125	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OKX01_13130	COG1674	ftsk spoiiie
OKX01_13135	COG0492	ferredoxin-NADP+ reductase activity
OKX01_13155	COG0477	Major facilitator Superfamily
OKX01_13175	COG2272	Belongs to the type-B carboxylesterase lipase family
OKX01_13180	COG1960	acyl-CoA dehydrogenase activity
OKX01_13205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OKX01_13225	COG2204	response regulator
OKX01_13265	COG4964	Belongs to the GSP D family
OKX01_13325	COG0612	Peptidase, M16
OKX01_13330	COG0484	heat shock protein binding
OKX01_13335	COG0443	Heat shock 70 kDa protein
OKX01_13340	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OKX01_13345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OKX01_13350	COG1420	regulation of RNA biosynthetic process
OKX01_13360	COG0497	DNA recombination
OKX01_13365	COG0735	belongs to the Fur family
OKX01_13370	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OKX01_13385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OKX01_13405	COG0582	viral genome integration into host DNA
OKX01_13415	COG1396	sequence-specific DNA binding
OKX01_13420	COG0583	DNA-binding transcription factor activity
OKX01_13430	COG0589	response to stress
OKX01_13435	COG0659	secondary active sulfate transmembrane transporter activity
OKX01_13440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OKX01_13445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OKX01_13450	COG0785	Cytochrome C biogenesis protein
OKX01_13520	COG3220	belongs to the UPF0276 family
OKX01_13535	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OKX01_13565	COG1595	DNA-templated transcription, initiation
OKX01_13595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OKX01_13605	COG1215	transferase activity, transferring glycosyl groups
OKX01_13625	COG2226	methyltransferase
OKX01_13630	COG0306	phosphate transporter
OKX01_13645	COG0798	PFAM Bile acid sodium symporter
OKX01_13665	COG0640	Transcriptional regulator
OKX01_13725	COG2003	Belongs to the UPF0758 family
OKX01_13835	COG3344	reverse transcriptase
OKX01_13895	COG0270	DNA (cytosine-5-)-methyltransferase activity
OKX01_13905	COG0629	single-stranded DNA binding
OKX01_13960	COG5001	Diguanylate cyclase
OKX01_13960	COG3300	MHYT domain
OKX01_13975	COG2814	Major facilitator Superfamily
OKX01_13990	COG0243	molybdopterin cofactor binding
OKX01_13990	COG3383	formate dehydrogenase (NAD+) activity
OKX01_13995	COG0437	4 iron, 4 sulfur cluster binding
OKX01_14000	COG2864	formate dehydrogenase
OKX01_14005	COG3058	Necessary for formate dehydrogenase activity
OKX01_14010	COG2819	hydrolase of the alpha beta superfamily
OKX01_14020	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OKX01_14020	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OKX01_14020	COG0506	proline dehydrogenase activity
OKX01_14035	COG2423	ornithine cyclodeaminase activity
OKX01_14040	COG0477	Major facilitator Superfamily
OKX01_14045	COG0513	Belongs to the DEAD box helicase family
OKX01_14050	COG0583	DNA-binding transcription factor activity
OKX01_14055	COG4638	Rieske (2fe-2S)
OKX01_14060	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OKX01_14075	COG0446	pyridine nucleotide-disulphide oxidoreductase
OKX01_14095	COG4569	acetaldehyde dehydrogenase (acetylating) activity
OKX01_14100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OKX01_14105	COG2814	Major facilitator Superfamily
OKX01_14120	COG0154	amidase activity
OKX01_14125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OKX01_14130	COG2814	Major facilitator Superfamily
OKX01_14160	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_14170	COG0842	Transport permease protein
OKX01_14175	COG0842	Transport permease protein
OKX01_14175	COG1129	ABC transporter
OKX01_14180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OKX01_14185	COG1538	Outer membrane efflux protein
OKX01_14190	COG3243	poly(R)-hydroxyalkanoic acid synthase
OKX01_14195	COG1309	transcriptional regulator
OKX01_14200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OKX01_14205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OKX01_14210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OKX01_14225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OKX01_14240	COG0505	Belongs to the CarA family
OKX01_14245	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OKX01_14255	COG0789	Transcriptional regulator
OKX01_14265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OKX01_14310	COG3278	Belongs to the heme-copper respiratory oxidase family
OKX01_14315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OKX01_14335	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OKX01_14415	COG0516	GMP reductase activity
OKX01_14415	COG0517	IMP dehydrogenase activity
OKX01_14430	COG1027	Aspartate ammonia-lyase
OKX01_14435	COG1846	Transcriptional regulator
OKX01_14445	COG0494	nUDIX hydrolase
OKX01_14450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OKX01_14455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OKX01_14470	COG1414	Transcriptional regulator
OKX01_14490	COG0513	Belongs to the DEAD box helicase family
OKX01_14510	COG0429	hydrolase of the alpha beta-hydrolase fold
OKX01_14535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OKX01_14545	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OKX01_14555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OKX01_14560	COG0632	four-way junction helicase activity
OKX01_14570	COG2255	four-way junction helicase activity
OKX01_14580	COG0418	dihydroorotase activity
OKX01_14590	COG0415	Belongs to the DNA photolyase family
OKX01_14650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OKX01_14685	COG1177	transmembrane transport
OKX01_14690	COG3842	ATPase activity
OKX01_14695	COG1840	ABC-type Fe3 transport system, periplasmic component
OKX01_14700	COG2084	Dehydrogenase
OKX01_14715	COG0494	nUDIX hydrolase
OKX01_14720	COG0442	prolyl-tRNA aminoacylation
OKX01_14725	COG0824	Thioesterase
OKX01_14730	COG0811	peptide transport
OKX01_14745	COG0823	Involved in the tonB-independent uptake of proteins
OKX01_14785	COG1079	Belongs to the binding-protein-dependent transport system permease family
OKX01_14790	COG4603	Belongs to the binding-protein-dependent transport system permease family
OKX01_14795	COG3845	ABC transporter
OKX01_14815	COG0427	acetyl-CoA hydrolase
OKX01_14820	COG0583	DNA-binding transcription factor activity
OKX01_14830	COG2814	Major facilitator Superfamily
OKX01_14845	COG3634	alkyl hydroperoxide reductase activity
OKX01_14860	COG0697	spore germination
OKX01_14865	COG0175	sulfate reduction
OKX01_14875	COG2895	sulfate adenylyltransferase (ATP) activity
OKX01_14885	COG1012	belongs to the aldehyde dehydrogenase family
OKX01_14890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OKX01_14895	COG5383	Protein conserved in bacteria
OKX01_14905	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OKX01_14920	COG0583	DNA-binding transcription factor activity
OKX01_14925	COG1741	Belongs to the pirin family
OKX01_14930	COG3706	GGDEF domain
OKX01_14935	COG0154	amidase activity
OKX01_14945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OKX01_14960	COG0284	orotidine-5'-phosphate decarboxylase activity
OKX01_14980	COG1414	Transcriptional regulator
OKX01_14990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OKX01_15000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OKX01_15005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OKX01_15030	COG0742	ribosomal rna small subunit methyltransferase
OKX01_15035	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OKX01_15040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OKX01_15070	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OKX01_15085	COG1335	isochorismatase
OKX01_15090	COG2309	aminopeptidase activity
OKX01_15095	COG0596	Alpha beta hydrolase
OKX01_15100	COG2010	Cytochrome c
OKX01_15100	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OKX01_15105	COG2080	2 iron, 2 sulfur cluster binding
OKX01_15110	COG2010	Cytochrome c
OKX01_15110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OKX01_15125	COG0411	ABC transporter
OKX01_15145	COG3706	GGDEF domain
OKX01_15160	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_15170	COG1234	tRNA 3'-trailer cleavage
OKX01_15175	COG2188	Transcriptional regulator
OKX01_15185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OKX01_15195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OKX01_15195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OKX01_15200	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OKX01_15200	COG3608	succinylglutamate desuccinylase aspartoacylase
OKX01_15205	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OKX01_15230	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OKX01_15255	COG1335	isochorismatase
OKX01_15260	COG2309	aminopeptidase activity
OKX01_15265	COG0596	Alpha beta hydrolase
OKX01_15280	COG1120	ATPase activity
OKX01_15285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKX01_15295	COG4206	TonB-dependent receptor
OKX01_15300	COG2031	fatty acid transporter
OKX01_15310	COG0402	S-adenosylhomocysteine deaminase activity
OKX01_15315	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_15330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OKX01_15335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OKX01_15340	COG0328	RNA-DNA hybrid ribonuclease activity
OKX01_15345	COG2226	methyltransferase
OKX01_15350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OKX01_15355	COG1388	LysM domain
OKX01_15355	COG0741	lytic transglycosylase activity
OKX01_15365	COG2204	response regulator
OKX01_15370	COG4191	Histidine kinase
OKX01_15375	COG1301	dicarboxylic acid transport
OKX01_15385	COG1054	Belongs to the UPF0176 family
OKX01_15405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OKX01_15430	COG0604	alcohol dehydrogenase
OKX01_15440	COG1024	Enoyl-CoA hydratase
OKX01_15460	COG1902	pentaerythritol trinitrate reductase activity
OKX01_15485	COG0583	DNA-binding transcription factor activity
OKX01_15490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OKX01_15495	COG1454	alcohol dehydrogenase
OKX01_15505	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OKX01_15515	COG0583	DNA-binding transcription factor activity
OKX01_15550	COG1393	Belongs to the ArsC family
OKX01_15555	COG0431	NADPH-dependent FMN reductase
OKX01_15560	COG0745	RESPONSE REGULATOR receiver
OKX01_15565	COG0642	Histidine kinase
OKX01_15580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OKX01_15580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OKX01_15585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OKX01_15590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OKX01_15595	COG1881	PFAM PEBP family protein
OKX01_15600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OKX01_15605	COG0739	heme binding
OKX01_15610	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OKX01_15615	COG0316	Belongs to the HesB IscA family
OKX01_15625	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OKX01_15630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OKX01_15635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OKX01_15640	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OKX01_15645	COG0312	modulator of DNA gyrase
OKX01_15650	COG3028	Belongs to the UPF0307 family
OKX01_15685	COG4566	intracellular signal transduction
OKX01_15690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OKX01_15695	COG4681	YaeQ
OKX01_15720	COG0762	integral membrane protein
OKX01_15725	COG2169	Transcriptional regulator
OKX01_15725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OKX01_15730	COG3133	Outer membrane lipoprotein
OKX01_15735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OKX01_15750	COG0439	Biotin carboxylase
OKX01_15755	COG0511	ligase activity, forming carbon-carbon bonds
OKX01_15760	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OKX01_15765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OKX01_15770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OKX01_15775	COG3150	esterase
OKX01_15790	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OKX01_15795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OKX01_15805	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OKX01_15820	COG1678	Uncharacterized ACR, COG1678
OKX01_15835	COG0352	thiamine-phosphate diphosphorylase activity
OKX01_15840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OKX01_15855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OKX01_15865	COG3237	CsbD-like
OKX01_15870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OKX01_15875	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OKX01_15880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OKX01_15885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OKX01_15910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OKX01_15925	COG1126	abc transporter atp-binding protein
OKX01_15930	COG0765	amino acid transport
OKX01_15935	COG4597	amino acid ABC transporter
OKX01_15940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OKX01_15945	COG2884	Cell division ATP-binding protein ftsE
OKX01_15950	COG2177	Part of the ABC transporter FtsEX involved in
OKX01_15960	COG0772	Belongs to the SEDS family
OKX01_15965	COG0768	penicillin binding
OKX01_15975	COG1792	Involved in formation and maintenance of cell shape
OKX01_15980	COG1077	Cell shape determining protein MreB Mrl
OKX01_15985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OKX01_15990	COG0154	amidase activity
OKX01_15995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OKX01_16000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OKX01_16005	COG0583	DNA-binding transcription factor activity
OKX01_16010	COG2259	Doxx family
OKX01_16015	COG3384	dioxygenase
OKX01_16025	COG3245	cytochrome
OKX01_16035	COG1846	Transcriptional regulator
OKX01_16040	COG1960	acyl-CoA dehydrogenase activity
OKX01_16045	COG2814	Major facilitator Superfamily
OKX01_16055	COG1024	Enoyl-CoA hydratase
OKX01_16065	COG3604	Transcriptional regulator
OKX01_16085	COG1309	transcriptional regulator
OKX01_16100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OKX01_16125	COG1090	epimerase
OKX01_16130	COG0786	glutamate:sodium symporter activity
OKX01_16135	COG0142	geranyltranstransferase activity
OKX01_16145	COG0494	nUDIX hydrolase
OKX01_16150	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OKX01_16175	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
OKX01_16180	COG0237	dephospho-CoA kinase activity
OKX01_16190	COG2197	response regulator
OKX01_16195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OKX01_16200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OKX01_16210	COG0477	Major facilitator Superfamily
OKX01_16225	COG4206	TonB-dependent receptor
OKX01_16230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OKX01_16245	COG1595	DNA-templated transcription, initiation
OKX01_16255	COG2022	thiamine diphosphate biosynthetic process
OKX01_16260	COG0351	phosphomethylpyrimidine kinase
OKX01_16265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OKX01_16270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OKX01_16280	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OKX01_16290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OKX01_16305	COG2226	methyltransferase
OKX01_16310	COG0745	RESPONSE REGULATOR receiver
OKX01_16315	COG5002	protein histidine kinase activity
OKX01_16325	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OKX01_16330	COG1984	allophanate hydrolase subunit 2
OKX01_16335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OKX01_16340	COG1238	metal cluster binding
OKX01_16370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OKX01_16375	COG4988	ABC transporter
OKX01_16385	COG1294	oxidase, subunit
OKX01_16390	COG1271	oxidase subunit
OKX01_16405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OKX01_16420	COG1137	ATPase activity
OKX01_16430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OKX01_16435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OKX01_16440	COG1660	Displays ATPase and GTPase activities
OKX01_16450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OKX01_16455	COG0792	nuclease activity
OKX01_16460	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OKX01_16475	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OKX01_16495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OKX01_16500	COG0793	Belongs to the peptidase S41A family
OKX01_16505	COG4942	peptidase
OKX01_16510	COG0588	phosphoglycerate mutase activity
OKX01_16515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OKX01_16525	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OKX01_16530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OKX01_16535	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_16540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OKX01_16545	COG1040	competence protein
OKX01_16550	COG2226	methyltransferase
OKX01_16560	COG2204	response regulator
OKX01_16580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OKX01_16595	COG3473	Maleate cis-trans isomerase
OKX01_16610	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OKX01_16640	COG0662	Cupin 2, conserved barrel domain protein
OKX01_16640	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OKX01_16645	COG1215	transferase activity, transferring glycosyl groups
OKX01_16655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OKX01_16670	COG1088	dTDP-glucose 4,6-dehydratase activity
OKX01_16675	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OKX01_16690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OKX01_16700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OKX01_16705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OKX01_16710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OKX01_16725	COG0356	it plays a direct role in the translocation of protons across the membrane
OKX01_16735	COG1024	Enoyl-CoA hydratase
OKX01_16750	COG0037	tRNA processing
OKX01_16760	COG0163	prenyltransferase activity
OKX01_16765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OKX01_16770	COG2890	protein-(glutamine-N5) methyltransferase activity
OKX01_16790	COG0582	viral genome integration into host DNA
OKX01_16965	COG4695	Portal protein
OKX01_17005	COG3180	Ammonia monooxygenase
OKX01_17025	COG5002	protein histidine kinase activity
OKX01_17040	COG0477	Major facilitator Superfamily
OKX01_17045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OKX01_17070	COG1116	anion transmembrane transporter activity
OKX01_17100	COG0437	4 iron, 4 sulfur cluster binding
OKX01_17105	COG2864	formate dehydrogenase
OKX01_17110	COG3058	Necessary for formate dehydrogenase activity
OKX01_17115	COG1921	L-seryl-tRNASec selenium transferase activity
OKX01_17120	COG3276	selenocysteine insertion sequence binding
OKX01_17130	COG1476	TRANSCRIPTIONal
OKX01_17135	COG0235	Class ii aldolase
OKX01_17145	COG3181	Tripartite tricarboxylate transporter family receptor
OKX01_17165	COG0709	Synthesizes selenophosphate from selenide and ATP
OKX01_17170	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
OKX01_17175	COG3901	Regulator of nitric oxide reductase transcription
OKX01_17175	COG0348	domain, Protein
OKX01_17180	COG4263	nitrous-oxide reductase activity
OKX01_17195	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OKX01_17210	COG0166	Belongs to the GPI family
OKX01_17225	COG1215	transferase activity, transferring glycosyl groups
OKX01_17235	COG0297	glycogen (starch) synthase activity
OKX01_17250	COG0662	Cupin 2, conserved barrel domain protein
OKX01_17250	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
OKX01_17265	COG0438	transferase activity, transferring glycosyl groups
OKX01_17275	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OKX01_17310	COG0156	8-amino-7-oxononanoate synthase activity
OKX01_17315	COG0604	alcohol dehydrogenase
OKX01_17315	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_17315	COG3321	synthase
OKX01_17320	COG2233	PERMEase
OKX01_17325	COG0697	spore germination
OKX01_17330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OKX01_17335	COG0697	spore germination
OKX01_17345	COG0183	Belongs to the thiolase family
OKX01_17350	COG1024	Enoyl-CoA hydratase
OKX01_17350	COG1250	3-hydroxyacyl-CoA dehydrogenase
OKX01_17365	COG1127	ABC transporter
OKX01_17370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OKX01_17375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OKX01_17390	COG1131	(ABC) transporter
OKX01_17395	COG0842	Transport permease protein
OKX01_17405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OKX01_17415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OKX01_17420	COG0131	Imidazoleglycerol-phosphate dehydratase
OKX01_17430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OKX01_17435	COG0107	imidazoleglycerol-phosphate synthase activity
OKX01_17445	COG0140	phosphoribosyl-ATP diphosphatase activity
OKX01_17450	COG0537	adenosine 5'-monophosphoramidase activity
OKX01_17455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OKX01_17460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OKX01_17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OKX01_17480	COG1970	mechanosensitive ion channel activity
OKX01_17485	COG0723	plastoquinol--plastocyanin reductase activity
OKX01_17490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OKX01_17495	COG2857	Cytochrome c1
OKX01_17500	COG0625	glutathione transferase activity
OKX01_17505	COG2969	positive regulation of protein catabolic process
OKX01_17510	COG4208	sulfate ABC transporter
OKX01_17515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OKX01_17520	COG4150	thiosulfate binding
OKX01_17540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKX01_17560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OKX01_17565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OKX01_17570	COG3622	Belongs to the hyi family
OKX01_17575	COG2084	Dehydrogenase
OKX01_17580	COG0129	dihydroxy-acid dehydratase activity
OKX01_17585	COG1802	Transcriptional regulator
OKX01_17590	COG1522	sequence-specific DNA binding
OKX01_17595	COG3483	tryptophan 2,3-dioxygenase activity
OKX01_17615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OKX01_17620	COG0656	L-ascorbic acid biosynthetic process
OKX01_17630	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OKX01_17635	COG3706	GGDEF domain
OKX01_17640	COG2226	methyltransferase
OKX01_17650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OKX01_17665	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
OKX01_17670	COG0583	DNA-binding transcription factor activity
OKX01_17675	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_17680	COG1335	isochorismatase
OKX01_17700	COG2823	Periplasmic or secreted lipoprotein
OKX01_17710	COG3284	Transcriptional regulator
OKX01_17740	COG1595	DNA-templated transcription, initiation
OKX01_17750	COG1522	sequence-specific DNA binding
OKX01_17760	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OKX01_17780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OKX01_17820	COG0109	protoheme IX farnesyltransferase activity
OKX01_17825	COG3177	Filamentation induced by cAMP protein fic
OKX01_17865	COG3568	Endonuclease Exonuclease Phosphatase
OKX01_17870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OKX01_17895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OKX01_17905	COG1228	amidohydrolase
OKX01_17925	COG2986	histidine ammonia-lyase
OKX01_17930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OKX01_17955	COG0789	Transcriptional regulator
OKX01_17975	COG0625	glutathione transferase activity
OKX01_18000	COG1448	Aminotransferase
OKX01_18005	COG2365	Tyrosine phosphatase family
OKX01_18010	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
OKX01_18020	COG0318	PFAM AMP-dependent synthetase and ligase
OKX01_18030	COG2030	dehydratase
OKX01_18040	COG1028	Short-chain dehydrogenase reductase Sdr
OKX01_18050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OKX01_18075	COG2423	ornithine cyclodeaminase activity
OKX01_18125	COG3069	C4-dicarboxylate transmembrane transporter activity
OKX01_18135	COG1802	Transcriptional regulator
OKX01_18145	COG2814	Major facilitator Superfamily
OKX01_18160	COG2814	Major facilitator Superfamily
OKX01_18170	COG2814	Major facilitator Superfamily
OKX01_18180	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OKX01_18185	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OKX01_18190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OKX01_18210	COG5001	Diguanylate cyclase
OKX01_18210	COG5002	protein histidine kinase activity
OKX01_18215	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OKX01_18220	COG1333	cytochrome c biogenesis protein
OKX01_18230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OKX01_18240	COG4232	protein-disulfide reductase activity
OKX01_18260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OKX01_18265	COG0203	ribosomal protein L17
OKX01_18270	COG0202	RNA polymerase activity
OKX01_18275	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OKX01_18280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OKX01_18285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OKX01_18290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OKX01_18300	COG0201	protein transport
OKX01_18305	COG0200	Binds to the 23S rRNA
OKX01_18310	COG1841	ribosomal large subunit assembly
OKX01_18315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OKX01_18320	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OKX01_18325	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OKX01_18330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OKX01_18335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OKX01_18340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OKX01_18345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OKX01_18350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OKX01_18375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OKX01_18380	COG2274	protein secretion by the type I secretion system
OKX01_18390	COG1538	Outer membrane efflux protein
OKX01_18415	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OKX01_18425	COG0647	UMP catabolic process
OKX01_18430	COG1737	Transcriptional regulator
OKX01_18445	COG1960	acyl-CoA dehydrogenase activity
OKX01_18450	COG0183	Belongs to the thiolase family
OKX01_18460	COG2067	long-chain fatty acid transport protein
OKX01_18475	COG0318	PFAM AMP-dependent synthetase and ligase
OKX01_18480	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OKX01_18485	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OKX01_18490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OKX01_18490	COG1648	precorrin-2 dehydrogenase activity
OKX01_18505	COG1116	anion transmembrane transporter activity
OKX01_18510	COG1960	acyl-CoA dehydrogenase activity
OKX01_18525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OKX01_18530	COG0255	Belongs to the universal ribosomal protein uL29 family
OKX01_18535	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OKX01_18540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OKX01_18545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OKX01_18550	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OKX01_18555	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OKX01_18560	COG0089	rRNA binding
OKX01_18565	COG0088	Forms part of the polypeptide exit tunnel
OKX01_18570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OKX01_18575	COG4175	Glycine betaine
OKX01_18580	COG4176	ABC-type proline glycine betaine transport system permease component
OKX01_18585	COG0051	transcription antitermination factor activity, RNA binding
OKX01_18590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OKX01_18595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OKX01_18600	COG0049	tRNA binding
OKX01_18605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OKX01_18635	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OKX01_18640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKX01_18645	COG0085	RNA polymerase activity
OKX01_18650	COG0222	ribosome binding
OKX01_18655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OKX01_18660	COG0081	regulation of translation
OKX01_18685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OKX01_18705	COG1475	DNA binding
OKX01_18710	COG1192	Involved in chromosome partitioning
OKX01_18715	COG0357	Ribosomal RNA small subunit methyltransferase G
OKX01_18720	COG0445	tRNA wobble uridine modification
OKX01_18725	COG0436	Aminotransferase
OKX01_18730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OKX01_18735	COG3706	GGDEF domain
OKX01_18740	COG0688	phosphatidylethanolamine metabolic process
OKX01_18750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OKX01_18795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OKX01_18840	COG0753	catalase activity
OKX01_18845	COG0706	membrane insertase activity
OKX01_18850	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OKX01_18855	COG0594	ribonuclease P activity
OKX01_18860	COG0230	Belongs to the bacterial ribosomal protein bL34 family