locus-tag	class	description
B5T_00001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B5T_00003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B5T_00007	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B5T_00011	COG0683	leucine binding
B5T_00012	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_00014	COG0751	glycine-tRNA ligase activity
B5T_00016	COG2818	Glycosylase
B5T_00017	COG0519	Catalyzes the synthesis of GMP from XMP
B5T_00017	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5T_00021	COG0189	ligase activity
B5T_00021	COG4067	protein conserved in archaea
B5T_00022	COG0179	Fumarylacetoacetate (FAA) hydrolase
B5T_00023	COG0277	FAD linked oxidase domain protein
B5T_00024	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_00033	COG0405	Gamma-glutamyltransferase
B5T_00037	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
B5T_00041	COG1414	Transcriptional regulator
B5T_00044	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B5T_00046	COG0429	hydrolase of the alpha beta-hydrolase fold
B5T_00047	COG0330	HflC and HflK could
B5T_00049	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B5T_00050	COG0154	amidase activity
B5T_00051	COG0640	Transcriptional regulator
B5T_00054	COG2814	Major facilitator Superfamily
B5T_00057	COG0433	COG0433 Predicted ATPase
B5T_00058	COG1047	Peptidyl-prolyl cis-trans
B5T_00062	COG2201	protein-glutamate methylesterase activity
B5T_00065	COG0840	transmembrane signaling receptor activity
B5T_00069	COG0189	ligase activity
B5T_00071	COG1678	Uncharacterized ACR, COG1678
B5T_00072	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B5T_00075	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B5T_00076	COG0540	Belongs to the ATCase OTCase family
B5T_00079	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5T_00080	COG0745	RESPONSE REGULATOR receiver
B5T_00081	COG0642	Histidine kinase
B5T_00084	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B5T_00085	COG0435	Glutathione S-transferase
B5T_00087	COG3093	addiction module antidote protein HigA
B5T_00093	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B5T_00099	COG1960	acyl-CoA dehydrogenase activity
B5T_00103	COG3239	Fatty acid desaturase
B5T_00104	COG0456	acetyltransferase
B5T_00105	COG0415	Belongs to the DNA photolyase family
B5T_00106	COG1024	Enoyl-CoA hydratase
B5T_00107	COG1960	acyl-CoA dehydrogenase activity
B5T_00109	COG0183	Belongs to the thiolase family
B5T_00112	COG3618	amidohydrolase
B5T_00113	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B5T_00114	COG0569	domain protein
B5T_00116	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B5T_00117	COG0242	peptide deformylase activity
B5T_00119	COG0758	DNA mediated transformation
B5T_00121	COG0009	L-threonylcarbamoyladenylate synthase
B5T_00122	COG0408	coproporphyrinogen oxidase activity
B5T_00123	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5T_00125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B5T_00126	COG0339	signal peptide processing
B5T_00131	COG3188	usher protein
B5T_00150	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B5T_00151	COG0583	DNA-binding transcription factor activity
B5T_00153	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B5T_00154	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B5T_00155	COG2272	Belongs to the type-B carboxylesterase lipase family
B5T_00159	COG3012	SEC-C Motif Domain Protein
B5T_00162	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B5T_00164	COG3391	amine dehydrogenase activity
B5T_00165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B5T_00166	COG1758	RNA polymerase activity
B5T_00167	COG0194	GDP metabolic process
B5T_00168	COG3608	succinylglutamate desuccinylase aspartoacylase
B5T_00171	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_00181	COG1561	YicC-like family, N-terminal region
B5T_00182	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B5T_00183	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B5T_00185	COG1309	transcriptional regulator
B5T_00186	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B5T_00188	COG0756	dUTP diphosphatase activity
B5T_00189	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B5T_00190	COG2003	Belongs to the UPF0758 family
B5T_00191	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B5T_00192	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B5T_00195	COG4964	Belongs to the GSP D family
B5T_00205	COG1414	Transcriptional regulator
B5T_00207	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_00208	COG0604	alcohol dehydrogenase
B5T_00208	COG3321	synthase
B5T_00208	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_00215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B5T_00218	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_00219	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_00220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B5T_00222	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_00222	COG2813	Specifically methylates the guanine in position
B5T_00224	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_00227	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B5T_00228	COG2022	thiamine diphosphate biosynthetic process
B5T_00230	COG2363	Small membrane protein
B5T_00232	COG2177	Part of the ABC transporter FtsEX involved in
B5T_00233	COG2884	Cell division ATP-binding protein ftsE
B5T_00234	COG0552	protein localization to endoplasmic reticulum
B5T_00235	COG0612	Peptidase, M16
B5T_00237	COG0742	ribosomal rna small subunit methyltransferase
B5T_00241	COG3123	guanosine phosphorylase activity
B5T_00243	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B5T_00244	COG0402	S-adenosylhomocysteine deaminase activity
B5T_00245	COG0534	Mate efflux family protein
B5T_00246	COG1473	amidohydrolase
B5T_00248	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B5T_00249	COG0583	DNA-binding transcription factor activity
B5T_00251	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B5T_00254	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B5T_00255	COG0640	Transcriptional regulator
B5T_00260	COG3290	protein histidine kinase activity
B5T_00261	COG4565	transcriptional regulatory protein
B5T_00263	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B5T_00264	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B5T_00265	COG0126	phosphoglycerate kinase activity
B5T_00272	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B5T_00279	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B5T_00281	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B5T_00284	COG3079	Belongs to the UPF0149 family
B5T_00285	COG0006	proline dipeptidase activity
B5T_00286	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B5T_00287	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B5T_00289	COG1178	ABC-type Fe3 transport system permease component
B5T_00293	COG4774	siderophore transport
B5T_00294	COG3712	iron ion homeostasis
B5T_00296	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B5T_00297	COG0509	glycine decarboxylation via glycine cleavage system
B5T_00298	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B5T_00299	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B5T_00308	COG1063	alcohol dehydrogenase
B5T_00309	COG1942	4-Oxalocrotonate Tautomerase
B5T_00316	COG0346	lactoylglutathione lyase activity
B5T_00325	COG2171	N-acyltransferase activity
B5T_00331	COG2433	Pfam Transposase IS66
B5T_00338	COG1944	ATP diphosphatase activity
B5T_00339	COG3034	peptidoglycan biosynthetic process
B5T_00342	COG0625	glutathione transferase activity
B5T_00347	COG3321	synthase
B5T_00347	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_00347	COG0604	alcohol dehydrogenase
B5T_00350	COG2226	methyltransferase
B5T_00360	COG0456	acetyltransferase
B5T_00361	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_00362	COG0625	glutathione transferase activity
B5T_00372	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_00373	COG1414	Transcriptional regulator
B5T_00374	COG1960	acyl-CoA dehydrogenase activity
B5T_00376	COG2823	Periplasmic or secreted lipoprotein
B5T_00376	COG1652	LysM domain
B5T_00381	COG3738	Protein conserved in bacteria
B5T_00383	COG0625	glutathione transferase activity
B5T_00392	COG0596	Alpha beta hydrolase
B5T_00393	COG2824	Alkylphosphonate utilization operon protein PhnA
B5T_00394	COG2031	fatty acid transporter
B5T_00396	COG0656	L-ascorbic acid biosynthetic process
B5T_00397	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B5T_00408	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_00409	COG0436	Aminotransferase
B5T_00411	COG4399	Belongs to the UPF0754 family
B5T_00413	COG0346	lactoylglutathione lyase activity
B5T_00422	COG2205	protein histidine kinase activity
B5T_00423	COG0745	RESPONSE REGULATOR receiver
B5T_00426	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_00430	COG3795	YCII-related domain
B5T_00431	COG4941	Belongs to the sigma-70 factor family
B5T_00435	COG0659	secondary active sulfate transmembrane transporter activity
B5T_00436	COG0730	response to heat
B5T_00438	COG2321	neutral zinc metallopeptidase
B5T_00442	COG2815	serine threonine protein kinase
B5T_00442	COG0515	serine threonine protein kinase
B5T_00443	COG2116	formate transmembrane transporter activity
B5T_00444	COG0586	Pfam SNARE associated Golgi protein
B5T_00445	COG0625	glutathione transferase activity
B5T_00447	COG0583	DNA-binding transcription factor activity
B5T_00449	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B5T_00453	COG0513	Belongs to the DEAD box helicase family
B5T_00458	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B5T_00459	COG2217	Heavy metal translocating P-type atpase
B5T_00463	COG1051	belongs to the nudix hydrolase family
B5T_00464	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
B5T_00466	COG0730	response to heat
B5T_00467	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B5T_00468	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B5T_00477	COG0488	(ABC) transporter
B5T_00479	COG1742	UPF0060 membrane protein
B5T_00484	COG1960	acyl-CoA dehydrogenase activity
B5T_00487	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B5T_00487	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B5T_00488	COG2801	Transposase and inactivated derivatives
B5T_00490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B5T_00491	COG0439	Biotin carboxylase
B5T_00493	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_00494	COG0545	Peptidyl-prolyl cis-trans isomerase
B5T_00496	COG1346	cytolysis
B5T_00498	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B5T_00500	COG2918	glutathione biosynthetic process
B5T_00501	COG2183	response to ionizing radiation
B5T_00503	COG0745	RESPONSE REGULATOR receiver
B5T_00504	COG2205	protein histidine kinase activity
B5T_00505	COG2814	Major facilitator Superfamily
B5T_00508	COG0129	dihydroxy-acid dehydratase activity
B5T_00510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B5T_00511	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_00513	COG2133	pyrroloquinoline quinone binding
B5T_00514	COG0625	glutathione transferase activity
B5T_00518	COG1309	transcriptional regulator
B5T_00521	COG1595	DNA-templated transcription, initiation
B5T_00522	COG3712	iron ion homeostasis
B5T_00523	COG4771	TonB-dependent receptor
B5T_00525	COG2951	lytic endotransglycosylase activity
B5T_00527	COG1252	NADH dehydrogenase
B5T_00528	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_00529	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_00530	COG1012	belongs to the aldehyde dehydrogenase family
B5T_00534	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B5T_00536	COG3391	amine dehydrogenase activity
B5T_00539	COG2207	Transcriptional regulator
B5T_00543	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B5T_00544	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B5T_00545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B5T_00546	COG1011	Hydrolase
B5T_00547	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_00550	COG0494	nUDIX hydrolase
B5T_00551	COG1218	3'(2'),5'-bisphosphate nucleotidase
B5T_00561	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_00564	COG0747	negative chemotaxis
B5T_00565	COG4608	Belongs to the ABC transporter superfamily
B5T_00566	COG0444	Belongs to the ABC transporter superfamily
B5T_00568	COG0439	Biotin carboxylase
B5T_00569	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_00585	COG1595	DNA-templated transcription, initiation
B5T_00586	COG0560	Phosphoserine phosphatase
B5T_00586	COG3830	Belongs to the UPF0237 family
B5T_00590	COG0131	Imidazoleglycerol-phosphate dehydratase
B5T_00591	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B5T_00592	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B5T_00593	COG0107	imidazoleglycerol-phosphate synthase activity
B5T_00594	COG1671	Belongs to the UPF0178 family
B5T_00598	COG0385	Bile acid
B5T_00599	COG2223	nitrite transmembrane transporter activity
B5T_00601	COG2146	nitrite reductase [NAD(P)H] activity
B5T_00601	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_00602	COG0243	molybdopterin cofactor binding
B5T_00603	COG0746	molybdenum cofactor guanylyltransferase activity
B5T_00604	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B5T_00605	COG0314	molybdopterin synthase activity
B5T_00606	COG0521	Mo-molybdopterin cofactor biosynthetic process
B5T_00606	COG0315	cyclic pyranopterin monophosphate synthase activity
B5T_00607	COG0303	'Molybdopterin
B5T_00608	COG0793	Belongs to the peptidase S41A family
B5T_00609	COG4942	peptidase
B5T_00610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5T_00612	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
B5T_00613	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B5T_00618	COG0189	ligase activity
B5T_00619	COG0482	sulfurtransferase activity
B5T_00621	COG0174	glutamine synthetase
B5T_00623	COG3852	Histidine kinase
B5T_00624	COG2204	response regulator
B5T_00626	COG1490	D-aminoacyl-tRNA deacylase activity
B5T_00629	COG1073	alpha beta
B5T_00629	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
B5T_00629	COG3064	Membrane
B5T_00631	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B5T_00632	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B5T_00633	COG0140	phosphoribosyl-ATP diphosphatase activity
B5T_00634	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B5T_00636	COG2226	methyltransferase
B5T_00638	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B5T_00638	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B5T_00639	COG0306	phosphate transporter
B5T_00640	COG1392	Phosphate transport regulator
B5T_00641	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B5T_00644	COG0859	PFAM glycosyl transferase family 9
B5T_00646	COG0859	PFAM glycosyl transferase family 9
B5T_00647	COG0438	transferase activity, transferring glycosyl groups
B5T_00649	COG0463	Glycosyl transferase, family 2
B5T_00651	COG0438	transferase activity, transferring glycosyl groups
B5T_00653	COG1560	Kdo2-lipid A biosynthetic process
B5T_00655	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B5T_00655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B5T_00656	COG2207	Transcriptional regulator
B5T_00658	COG0667	Aldo Keto reductase
B5T_00660	COG1519	Transferase
B5T_00661	COG1538	Outer membrane efflux protein
B5T_00662	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B5T_00664	COG0494	nUDIX hydrolase
B5T_00665	COG3151	Protein conserved in bacteria
B5T_00666	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B5T_00667	COG3501	Rhs element vgr protein
B5T_00671	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_00673	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_00675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B5T_00676	COG4566	intracellular signal transduction
B5T_00677	COG5507	3-demethylubiquinone-9 3-methyltransferase
B5T_00678	COG3150	esterase
B5T_00681	COG0204	Acyl-transferase
B5T_00683	COG3122	Protein conserved in bacteria
B5T_00685	COG2366	antibiotic biosynthetic process
B5T_00687	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_00690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B5T_00691	COG1509	lysine 2,3-aminomutase activity
B5T_00697	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_00702	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_00703	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_00704	COG0583	DNA-binding transcription factor activity
B5T_00705	COG0667	Aldo Keto reductase
B5T_00706	COG0583	DNA-binding transcription factor activity
B5T_00707	COG1024	Enoyl-CoA hydratase
B5T_00711	COG0473	3-isopropylmalate dehydrogenase activity
B5T_00712	COG2207	Transcriptional regulator
B5T_00713	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_00717	COG3781	membrane
B5T_00718	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B5T_00719	COG2375	cellular response to nickel ion
B5T_00721	COG3239	Fatty acid desaturase
B5T_00724	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B5T_00725	COG0259	pyridoxamine-phosphate oxidase activity
B5T_00734	COG0410	ABC transporter
B5T_00737	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_00739	COG1802	Transcriptional regulator
B5T_00740	COG0439	Biotin carboxylase
B5T_00743	COG0583	DNA-binding transcription factor activity
B5T_00747	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_00750	COG1335	isochorismatase
B5T_00753	COG0739	heme binding
B5T_00754	COG1595	DNA-templated transcription, initiation
B5T_00755	COG3712	iron ion homeostasis
B5T_00756	COG4774	siderophore transport
B5T_00758	COG2814	Major facilitator Superfamily
B5T_00759	COG1309	transcriptional regulator
B5T_00760	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
B5T_00761	COG1194	a g-specific adenine glycosylase
B5T_00764	COG0688	phosphatidylethanolamine metabolic process
B5T_00766	COG1162	GTPase activity
B5T_00767	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B5T_00769	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B5T_00769	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B5T_00770	COG0802	atpase or kinase
B5T_00771	COG0860	N-Acetylmuramoyl-L-alanine amidase
B5T_00773	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B5T_00774	COG1923	regulation of RNA biosynthetic process
B5T_00775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B5T_00776	COG0330	HflC and HflK could
B5T_00777	COG0330	HflC and HflK could
B5T_00779	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B5T_00780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B5T_00783	COG1785	Belongs to the alkaline phosphatase family
B5T_00789	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5T_00790	COG0360	Binds together with S18 to 16S ribosomal RNA
B5T_00792	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B5T_00793	COG0359	binds to the 23S rRNA
B5T_00794	COG0305	Participates in initiation and elongation during chromosome replication
B5T_00795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B5T_00796	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B5T_00797	COG0569	domain protein
B5T_00798	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B5T_00803	COG2226	methyltransferase
B5T_00806	COG3712	iron ion homeostasis
B5T_00810	COG2259	Doxx family
B5T_00813	COG0488	(ABC) transporter
B5T_00815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B5T_00817	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B5T_00818	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B5T_00818	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B5T_00821	COG3396	Phenylacetate-CoA oxygenase
B5T_00822	COG3460	Phenylacetate-CoA oxygenase
B5T_00823	COG3396	Phenylacetate-CoA oxygenase
B5T_00824	COG2151	metal-sulfur cluster biosynthetic enzyme
B5T_00825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B5T_00826	COG2030	dehydratase
B5T_00826	COG1012	belongs to the aldehyde dehydrogenase family
B5T_00828	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B5T_00831	COG0737	Belongs to the 5'-nucleotidase family
B5T_00833	COG0456	acetyltransferase
B5T_00837	COG0681	Belongs to the peptidase S26 family
B5T_00841	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_00843	COG3327	negative regulation of DNA-templated transcription, initiation
B5T_00844	COG1024	Enoyl-CoA hydratase
B5T_00845	COG2050	protein possibly involved in aromatic compounds catabolism
B5T_00849	COG2197	response regulator
B5T_00856	COG0583	DNA-binding transcription factor activity
B5T_00862	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B5T_00863	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B5T_00864	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B5T_00865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B5T_00866	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B5T_00867	COG0142	geranyltranstransferase activity
B5T_00870	COG0745	RESPONSE REGULATOR receiver
B5T_00871	COG3539	Fimbrial protein
B5T_00872	COG3121	Chaperone
B5T_00876	COG2205	protein histidine kinase activity
B5T_00876	COG0784	Response regulator, receiver
B5T_00878	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_00882	COG5002	protein histidine kinase activity
B5T_00884	COG0662	Cupin 2, conserved barrel domain protein
B5T_00885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B5T_00887	COG1846	Transcriptional regulator
B5T_00888	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_00890	COG1469	GTP cyclohydrolase I activity
B5T_00895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B5T_00896	COG0215	cysteine-tRNA ligase activity
B5T_00897	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B5T_00899	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B5T_00900	COG2203	Gaf domain
B5T_00900	COG5001	Diguanylate cyclase
B5T_00900	COG4251	negative regulation of phosphorylation
B5T_00900	COG3706	GGDEF domain
B5T_00904	COG0537	adenosine 5'-monophosphoramidase activity
B5T_00909	COG1307	EDD domain protein, DegV family
B5T_00913	COG0300	oxidoreductase activity
B5T_00921	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
B5T_00922	COG2835	tetraacyldisaccharide 4'-kinase activity
B5T_00923	COG1960	acyl-CoA dehydrogenase activity
B5T_00924	COG2832	Protein of unknown function (DUF454)
B5T_00925	COG1960	acyl-CoA dehydrogenase activity
B5T_00935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5T_00941	COG2771	luxR family
B5T_00942	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B5T_00944	COG2771	luxR family
B5T_00960	COG2354	Protein conserved in bacteria
B5T_00961	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B5T_00964	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B5T_00965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B5T_00966	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B5T_00967	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B5T_00971	COG0617	tRNA 3'-terminal CCA addition
B5T_00973	COG2719	SpoVR family
B5T_00974	COG2718	Belongs to the UPF0229 family
B5T_00975	COG2766	serine protein kinase
B5T_00977	COG2967	ApaG domain
B5T_00978	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B5T_00979	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B5T_00980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5T_00981	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
B5T_00984	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B5T_00986	COG0791	NLP P60 protein
B5T_00989	COG0477	Major facilitator Superfamily
B5T_00990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B5T_00991	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B5T_00992	COG1845	cytochrome c oxidase, subunit III
B5T_00993	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B5T_00996	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B5T_00997	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B5T_00998	COG0512	Glutamine amidotransferase of anthranilate synthase
B5T_00999	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B5T_01000	COG0134	indole-3-glycerol-phosphate synthase activity
B5T_01002	COG1765	OsmC-like protein
B5T_01003	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B5T_01004	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
B5T_01005	COG2205	protein histidine kinase activity
B5T_01005	COG0784	Response regulator, receiver
B5T_01005	COG5002	protein histidine kinase activity
B5T_01006	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_01007	COG0730	response to heat
B5T_01008	COG0151	Belongs to the GarS family
B5T_01009	COG0138	bifunctional purine biosynthesis protein purh
B5T_01013	COG2264	protein methyltransferase activity
B5T_01017	COG0511	ligase activity, forming carbon-carbon bonds
B5T_01018	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B5T_01023	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B5T_01024	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B5T_01029	COG0747	negative chemotaxis
B5T_01031	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5T_01034	COG2267	carboxylic ester hydrolase activity
B5T_01035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B5T_01043	COG0205	6-phosphofructokinase activity
B5T_01045	COG0745	RESPONSE REGULATOR receiver
B5T_01046	COG0784	Response regulator, receiver
B5T_01046	COG2198	Histidine kinase
B5T_01046	COG2205	protein histidine kinase activity
B5T_01046	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5T_01051	COG0411	ABC transporter
B5T_01053	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_01058	COG4774	siderophore transport
B5T_01059	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B5T_01060	COG0163	prenyltransferase activity
B5T_01061	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B5T_01064	COG0811	peptide transport
B5T_01065	COG3015	lipoprotein NlpE involved in copper resistance
B5T_01070	COG2807	transmembrane transport
B5T_01071	COG1846	Transcriptional regulator
B5T_01072	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B5T_01073	COG0321	lipoyl(octanoyl) transferase activity
B5T_01076	COG1686	Belongs to the peptidase S11 family
B5T_01078	COG2951	lytic endotransglycosylase activity
B5T_01079	COG0772	Belongs to the SEDS family
B5T_01080	COG0768	penicillin binding
B5T_01081	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B5T_01083	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B5T_01084	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B5T_01088	COG0495	leucyl-tRNA aminoacylation
B5T_01090	COG0471	metal ion transport
B5T_01091	COG0659	secondary active sulfate transmembrane transporter activity
B5T_01092	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5T_01095	COG0815	Transfers the fatty acyl group on membrane lipoproteins
B5T_01096	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B5T_01097	COG4535	Mg2 and Co2 transporter CorC
B5T_01098	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B5T_01099	COG1702	phosphate starvation-inducible protein PhoH
B5T_01100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B5T_01101	COG4208	sulfate ABC transporter
B5T_01103	COG4150	thiosulfate binding
B5T_01104	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B5T_01105	COG1999	signal sequence binding
B5T_01112	COG2020	methyltransferase activity
B5T_01113	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B5T_01117	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5T_01123	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_01124	COG1278	Cold shock
B5T_01127	COG0501	Belongs to the peptidase M48B family
B5T_01128	COG1704	LemA family
B5T_01129	COG0109	protoheme IX farnesyltransferase activity
B5T_01130	COG1612	heme a metabolic process
B5T_01136	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
B5T_01137	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B5T_01138	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B5T_01151	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B5T_01152	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_01153	COG1022	Amp-dependent synthetase and ligase
B5T_01155	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_01160	COG3284	Transcriptional regulator
B5T_01163	COG0439	Biotin carboxylase
B5T_01167	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_01172	COG2827	Endonuclease containing a URI domain
B5T_01174	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B5T_01180	COG1959	2 iron, 2 sulfur cluster binding
B5T_01181	COG1104	cysteine desulfurase activity
B5T_01183	COG2166	iron-sulfur cluster assembly
B5T_01184	COG2151	metal-sulfur cluster biosynthetic enzyme
B5T_01185	COG0316	Belongs to the HesB IscA family
B5T_01186	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B5T_01187	COG0719	Fe-S assembly protein
B5T_01188	COG0396	ATPase activity
B5T_01189	COG0719	Fe-S assembly protein
B5T_01190	COG0105	UTP biosynthetic process
B5T_01191	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B5T_01193	COG1426	Protein conserved in bacteria
B5T_01194	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B5T_01195	COG0124	histidyl-tRNA synthetase
B5T_01198	COG1160	GTP binding
B5T_01201	COG0784	Response regulator, receiver
B5T_01201	COG2205	protein histidine kinase activity
B5T_01201	COG5002	protein histidine kinase activity
B5T_01202	COG1570	exodeoxyribonuclease VII activity
B5T_01204	COG0519	Catalyzes the synthesis of GMP from XMP
B5T_01204	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5T_01207	COG5290	Psort location Cytoplasmic, score
B5T_01208	COG0519	Catalyzes the synthesis of GMP from XMP
B5T_01208	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B5T_01212	COG0494	nUDIX hydrolase
B5T_01213	COG2205	protein histidine kinase activity
B5T_01214	COG0745	RESPONSE REGULATOR receiver
B5T_01216	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_01217	COG1538	Outer membrane efflux protein
B5T_01219	COG1595	DNA-templated transcription, initiation
B5T_01220	COG3712	iron ion homeostasis
B5T_01222	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01223	COG1733	regulation of RNA biosynthetic process
B5T_01226	COG0179	Fumarylacetoacetate (FAA) hydrolase
B5T_01230	COG1309	transcriptional regulator
B5T_01236	COG3609	addiction module antidote protein, CC2985 family
B5T_01237	COG3668	Plasmid stabilization system
B5T_01241	COG2433	Pfam Transposase IS66
B5T_01246	COG0556	nucleotide-excision repair
B5T_01247	COG0326	Molecular chaperone. Has ATPase activity
B5T_01252	COG1304	FMN binding
B5T_01254	COG1595	DNA-templated transcription, initiation
B5T_01255	COG3712	iron ion homeostasis
B5T_01260	COG0583	DNA-binding transcription factor activity
B5T_01262	COG1335	isochorismatase
B5T_01264	COG1335	isochorismatase
B5T_01266	COG0667	Aldo Keto reductase
B5T_01273	COG0024	Methionine aminopeptidase
B5T_01277	COG1733	regulation of RNA biosynthetic process
B5T_01278	COG2814	Major facilitator Superfamily
B5T_01279	COG2272	Belongs to the type-B carboxylesterase lipase family
B5T_01280	COG2272	Belongs to the type-B carboxylesterase lipase family
B5T_01284	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B5T_01286	COG0251	oxidation-reduction process
B5T_01290	COG2207	Transcriptional regulator
B5T_01290	COG0662	Cupin 2, conserved barrel domain protein
B5T_01293	COG3457	Alanine racemase
B5T_01294	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01295	COG2207	Transcriptional regulator
B5T_01299	COG2207	Transcriptional regulator
B5T_01303	COG3541	Predicted nucleotidyltransferase
B5T_01304	COG4774	siderophore transport
B5T_01310	COG0693	protein deglycase activity
B5T_01311	COG4638	Rieske (2fe-2S)
B5T_01313	COG0667	Aldo Keto reductase
B5T_01323	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
B5T_01328	COG2226	methyltransferase
B5T_01333	COG4993	Dehydrogenase
B5T_01334	COG0477	Major facilitator Superfamily
B5T_01336	COG0583	DNA-binding transcription factor activity
B5T_01337	COG1960	acyl-CoA dehydrogenase activity
B5T_01338	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_01339	COG3795	YCII-related domain
B5T_01343	COG0477	Major facilitator Superfamily
B5T_01345	COG0583	DNA-binding transcription factor activity
B5T_01350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B5T_01352	COG2910	NAD(P)H-binding
B5T_01357	COG0251	oxidation-reduction process
B5T_01358	COG3181	Tripartite tricarboxylate transporter family receptor
B5T_01359	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B5T_01363	COG3971	2-oxopent-4-enoate hydratase activity
B5T_01367	COG1012	belongs to the aldehyde dehydrogenase family
B5T_01372	COG1595	DNA-templated transcription, initiation
B5T_01381	COG0848	biopolymer transport protein
B5T_01383	COG4558	Periplasmic binding protein
B5T_01384	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5T_01385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
B5T_01387	COG1121	(ABC) transporter
B5T_01388	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5T_01389	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5T_01392	COG1024	Enoyl-CoA hydratase
B5T_01393	COG0183	Belongs to the thiolase family
B5T_01396	COG1309	transcriptional regulator
B5T_01401	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
B5T_01402	COG0590	tRNA wobble adenosine to inosine editing
B5T_01403	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B5T_01406	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B5T_01406	COG3323	Protein of unknown function (DUF1653)
B5T_01407	COG2816	NAD+ diphosphatase activity
B5T_01408	COG0494	nUDIX hydrolase
B5T_01411	COG1752	Esterase of the alpha-beta hydrolase superfamily
B5T_01413	COG2801	Transposase and inactivated derivatives
B5T_01414	COG4536	flavin adenine dinucleotide binding
B5T_01416	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B5T_01417	COG0228	four-way junction DNA binding
B5T_01418	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B5T_01419	COG0336	Belongs to the RNA methyltransferase TrmD family
B5T_01420	COG0335	large ribosomal subunit rRNA binding
B5T_01424	COG0436	Aminotransferase
B5T_01426	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B5T_01431	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_01432	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5T_01433	COG2264	protein methyltransferase activity
B5T_01439	COG4953	penicillin-binding protein 1C
B5T_01446	COG1196	nuclear chromosome segregation
B5T_01446	COG3264	Mechanosensitive ion channel
B5T_01449	COG0709	Synthesizes selenophosphate from selenide and ATP
B5T_01450	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
B5T_01452	COG1309	transcriptional regulator
B5T_01457	COG3030	protein affecting phage T7 exclusion by the F plasmid
B5T_01459	COG0183	Belongs to the thiolase family
B5T_01460	COG1946	Acyl-CoA thioesterase
B5T_01463	COG0745	RESPONSE REGULATOR receiver
B5T_01464	COG2205	protein histidine kinase activity
B5T_01466	COG1902	pentaerythritol trinitrate reductase activity
B5T_01466	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5T_01467	COG1960	acyl-CoA dehydrogenase activity
B5T_01468	COG1960	acyl-CoA dehydrogenase activity
B5T_01472	COG1115	amino acid carrier protein
B5T_01478	COG3360	Dodecin
B5T_01485	COG4771	TonB-dependent receptor
B5T_01488	COG0175	sulfate reduction
B5T_01490	COG2267	carboxylic ester hydrolase activity
B5T_01495	COG1063	alcohol dehydrogenase
B5T_01499	COG0583	DNA-binding transcription factor activity
B5T_01502	COG4774	siderophore transport
B5T_01505	COG0488	(ABC) transporter
B5T_01516	COG0183	Belongs to the thiolase family
B5T_01517	COG1024	Enoyl-CoA hydratase
B5T_01517	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_01518	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B5T_01521	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B5T_01523	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B5T_01524	COG1024	Enoyl-CoA hydratase
B5T_01525	COG2070	2-Nitropropane dioxygenase
B5T_01534	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5T_01535	COG0481	GTPase activity
B5T_01538	COG0571	ribonuclease III activity
B5T_01540	COG1381	Involved in DNA repair and RecF pathway recombination
B5T_01541	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B5T_01542	COG0784	Response regulator, receiver
B5T_01542	COG5002	protein histidine kinase activity
B5T_01542	COG2205	protein histidine kinase activity
B5T_01545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B5T_01546	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B5T_01547	COG3956	TIGRFAM MazG family protein
B5T_01551	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B5T_01553	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5T_01554	COG3088	subunit of a heme lyase
B5T_01556	COG0563	adenylate kinase activity
B5T_01560	COG0511	ligase activity, forming carbon-carbon bonds
B5T_01560	COG5016	pyruvate
B5T_01561	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B5T_01563	COG1116	anion transmembrane transporter activity
B5T_01563	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_01564	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_01565	COG1116	anion transmembrane transporter activity
B5T_01566	COG3707	response regulator
B5T_01567	COG1116	anion transmembrane transporter activity
B5T_01567	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_01568	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B5T_01569	COG0583	DNA-binding transcription factor activity
B5T_01570	COG2076	Multidrug Resistance protein
B5T_01572	COG4133	protoheme IX ABC transporter activity
B5T_01576	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
B5T_01585	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01591	COG1131	(ABC) transporter
B5T_01592	COG0842	Transport permease protein
B5T_01593	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B5T_01593	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B5T_01594	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
B5T_01596	COG0778	Nitroreductase
B5T_01605	COG0583	DNA-binding transcription factor activity
B5T_01614	COG0183	Belongs to the thiolase family
B5T_01615	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01617	COG1960	acyl-CoA dehydrogenase activity
B5T_01618	COG1960	acyl-CoA dehydrogenase activity
B5T_01619	COG1309	transcriptional regulator
B5T_01620	COG1024	Enoyl-CoA hydratase
B5T_01624	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01628	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_01637	COG0784	Response regulator, receiver
B5T_01637	COG2205	protein histidine kinase activity
B5T_01643	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_01644	COG1012	belongs to the aldehyde dehydrogenase family
B5T_01647	COG1538	Outer membrane efflux protein
B5T_01648	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_01649	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_01650	COG1309	transcriptional regulator
B5T_01651	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01654	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_01655	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_01657	COG0411	ABC transporter
B5T_01658	COG0410	ABC transporter
B5T_01660	COG1024	Enoyl-CoA hydratase
B5T_01660	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_01661	COG1960	acyl-CoA dehydrogenase activity
B5T_01662	COG1960	acyl-CoA dehydrogenase activity
B5T_01663	COG2130	NADP-dependent
B5T_01665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5T_01666	COG0281	malic enzyme
B5T_01666	COG0280	phosphate acetyltransferase
B5T_01667	COG0235	Class ii aldolase
B5T_01674	COG2030	dehydratase
B5T_01675	COG1960	acyl-CoA dehydrogenase activity
B5T_01676	COG1024	Enoyl-CoA hydratase
B5T_01677	COG1960	acyl-CoA dehydrogenase activity
B5T_01678	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01683	COG1960	acyl-CoA dehydrogenase activity
B5T_01684	COG0183	Belongs to the thiolase family
B5T_01685	COG1846	Transcriptional regulator
B5T_01686	COG1764	response to oxidative stress
B5T_01693	COG1739	Uncharacterized protein family UPF0029
B5T_01698	COG0489	protein tyrosine kinase activity
B5T_01698	COG3206	protein involved in exopolysaccharide biosynthesis
B5T_01699	COG0471	metal ion transport
B5T_01699	COG3273	potassium ion transport
B5T_01700	COG0529	Catalyzes the synthesis of activated sulfate
B5T_01701	COG0250	Participates in transcription elongation, termination and antitermination
B5T_01706	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
B5T_01718	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5T_01721	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B5T_01726	COG2433	Pfam Transposase IS66
B5T_01730	COG3549	Plasmid maintenance system killer
B5T_01731	COG3093	addiction module antidote protein HigA
B5T_01736	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_01738	COG0183	Belongs to the thiolase family
B5T_01739	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_01740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B5T_01746	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B5T_01748	COG0166	Belongs to the GPI family
B5T_01753	COG1215	transferase activity, transferring glycosyl groups
B5T_01754	COG1216	Glycosyl transferase, family 2
B5T_01760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B5T_01769	COG3791	Glutathione-dependent formaldehyde-activating
B5T_01772	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5T_01774	COG3115	cell septum assembly
B5T_01775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B5T_01778	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B5T_01778	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B5T_01781	COG5002	protein histidine kinase activity
B5T_01781	COG0784	Response regulator, receiver
B5T_01781	COG2205	protein histidine kinase activity
B5T_01783	COG4106	trans-aconitate 2-methyltransferase activity
B5T_01784	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_01791	COG0583	DNA-binding transcription factor activity
B5T_01792	COG3527	Alpha-acetolactate decarboxylase
B5T_01798	COG1024	Enoyl-CoA hydratase
B5T_01799	COG1960	acyl-CoA dehydrogenase activity
B5T_01800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B5T_01801	COG4221	oxidoreductase activity
B5T_01806	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_01807	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B5T_01809	COG0308	aminopeptidase N
B5T_01812	COG3130	regulation of translation
B5T_01813	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B5T_01813	COG0116	Belongs to the methyltransferase superfamily
B5T_01815	COG0084	hydrolase, TatD family'
B5T_01817	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B5T_01819	COG0589	response to stress
B5T_01823	COG1309	transcriptional regulator
B5T_01824	COG1376	ErfK ybiS ycfS ynhG family protein
B5T_01826	COG0668	transmembrane transport
B5T_01836	COG2081	HI0933 family
B5T_01837	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B5T_01838	COG1946	Acyl-CoA thioesterase
B5T_01840	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B5T_01841	COG1805	sodium ion transport
B5T_01844	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
B5T_01845	COG2871	sodium ion transport
B5T_01846	COG1477	protein flavinylation
B5T_01847	COG2991	Protein conserved in bacteria
B5T_01850	COG0584	glycerophosphoryl diester phosphodiesterase
B5T_01855	COG0583	DNA-binding transcription factor activity
B5T_01858	COG0625	glutathione transferase activity
B5T_01861	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_01862	COG2957	Belongs to the agmatine deiminase family
B5T_01865	COG1136	(ABC) transporter
B5T_01866	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B5T_01868	COG0714	Associated with various cellular activities
B5T_01875	COG1393	Belongs to the ArsC family
B5T_01876	COG1959	2 iron, 2 sulfur cluster binding
B5T_01876	COG1295	ribonuclease BN
B5T_01877	COG1254	Belongs to the acylphosphatase family
B5T_01889	COG0410	ABC transporter
B5T_01892	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_01893	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
B5T_01894	COG2894	cell division
B5T_01895	COG0850	regulation of cytokinetic process
B5T_01896	COG2026	Addiction module toxin, RelE StbE family
B5T_01898	COG3550	peptidyl-serine autophosphorylation
B5T_01901	COG3118	belongs to the thioredoxin family
B5T_01902	COG0004	ammonium transporteR
B5T_01904	COG2326	polyphosphate kinase activity
B5T_01906	COG1199	ATP-dependent helicase activity
B5T_01909	COG1968	undecaprenyl-diphosphatase activity
B5T_01910	COG0742	ribosomal rna small subunit methyltransferase
B5T_01911	COG2937	Belongs to the GPAT DAPAT family
B5T_01915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B5T_01917	COG1393	Belongs to the ArsC family
B5T_01918	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5T_01919	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B5T_01920	COG0024	Methionine aminopeptidase
B5T_01921	COG0052	Belongs to the universal ribosomal protein uS2 family
B5T_01922	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B5T_01923	COG0528	UMP kinase activity
B5T_01924	COG0233	cytoplasmic translational termination
B5T_01925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B5T_01926	COG0575	Belongs to the CDS family
B5T_01927	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B5T_01931	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B5T_01932	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B5T_01934	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B5T_01935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B5T_01936	COG0587	DNA-directed DNA polymerase activity
B5T_01937	COG0825	malonyl-CoA metabolic process
B5T_01938	COG0037	tRNA processing
B5T_01941	COG0504	CTP synthase activity
B5T_01942	COG2877	3-deoxy-8-phosphooctulonate synthase activity
B5T_01943	COG0148	phosphopyruvate hydratase activity
B5T_01944	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B5T_01946	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B5T_01947	COG0585	pseudouridine synthase activity
B5T_01948	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B5T_01956	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_01958	COG0300	oxidoreductase activity
B5T_01959	COG0037	tRNA processing
B5T_01960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B5T_01961	COG0583	DNA-binding transcription factor activity
B5T_01962	COG2814	Major facilitator Superfamily
B5T_01963	COG0667	Aldo Keto reductase
B5T_01967	COG0667	Aldo Keto reductase
B5T_01970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B5T_01973	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
B5T_01975	COG2850	peptidyl-arginine hydroxylation
B5T_01977	COG2915	High frequency lysogenization protein hflD homolog
B5T_01978	COG0482	sulfurtransferase activity
B5T_01982	COG1278	Cold shock
B5T_01983	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B5T_01984	COG0542	response to heat
B5T_01985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B5T_01986	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
B5T_01987	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_01988	COG4774	siderophore transport
B5T_01989	COG3712	iron ion homeostasis
B5T_01990	COG1595	DNA-templated transcription, initiation
B5T_01991	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B5T_01992	COG0492	ferredoxin-NADP+ reductase activity
B5T_01993	COG1674	ftsk spoiiie
B5T_01994	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B5T_01995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B5T_01996	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B5T_01997	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B5T_01998	COG1648	precorrin-2 dehydrogenase activity
B5T_01998	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B5T_01999	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B5T_02002	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B5T_02006	COG2274	protein secretion by the type I secretion system
B5T_02007	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_02009	COG0477	Major facilitator Superfamily
B5T_02012	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02017	COG1960	acyl-CoA dehydrogenase activity
B5T_02018	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
B5T_02021	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_02024	COG1960	acyl-CoA dehydrogenase activity
B5T_02025	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_02026	COG1802	Transcriptional regulator
B5T_02028	COG1280	lysine exporter protein (LysE YggA)
B5T_02029	COG0003	Pfam Anion-transporting ATPase
B5T_02031	COG1966	Carbon starvation protein
B5T_02032	COG2197	response regulator
B5T_02033	COG0322	excinuclease ABC activity
B5T_02034	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B5T_02046	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_02047	COG1960	acyl-CoA dehydrogenase activity
B5T_02059	COG1021	2,3-dihydroxybenzoate-AMP ligase
B5T_02060	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_02062	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02064	COG2030	dehydratase
B5T_02065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B5T_02074	COG0633	Ferredoxin
B5T_02078	COG1309	transcriptional regulator
B5T_02082	COG2801	Transposase and inactivated derivatives
B5T_02090	COG3209	COG3209 Rhs family protein
B5T_02101	COG3501	Rhs element vgr protein
B5T_02105	COG1074	ATP-dependent DNA helicase activity
B5T_02138	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B5T_02152	COG1192	Involved in chromosome partitioning
B5T_02154	COG5295	Hep Hag repeat protein
B5T_02158	COG1414	Transcriptional regulator
B5T_02159	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B5T_02164	COG0683	leucine binding
B5T_02170	COG2130	NADP-dependent
B5T_02171	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B5T_02172	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_02174	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_02176	COG4977	sequence-specific DNA binding
B5T_02206	COG2205	protein histidine kinase activity
B5T_02206	COG0784	Response regulator, receiver
B5T_02207	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B5T_02210	COG3437	response regulator, receiver
B5T_02217	COG3156	type II secretion system protein K
B5T_02222	COG0646	methionine synthase
B5T_02222	COG1410	methionine synthase
B5T_02224	COG2813	Specifically methylates the guanine in position
B5T_02225	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
B5T_02226	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B5T_02227	COG0235	Class ii aldolase
B5T_02228	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B5T_02235	COG0560	Phosphoserine phosphatase
B5T_02239	COG0616	signal peptide processing
B5T_02240	COG0604	alcohol dehydrogenase
B5T_02243	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_02245	COG0534	Mate efflux family protein
B5T_02246	COG0316	Belongs to the HesB IscA family
B5T_02246	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B5T_02247	COG0501	Belongs to the peptidase M48B family
B5T_02248	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B5T_02251	COG0564	pseudouridine synthase activity
B5T_02252	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B5T_02256	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B5T_02262	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
B5T_02263	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B5T_02264	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B5T_02265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B5T_02268	COG0700	Nucleoside recognition
B5T_02270	COG0598	Magnesium transport protein CorA
B5T_02273	COG3022	response to hydroperoxide
B5T_02274	COG0589	response to stress
B5T_02275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_02281	COG0348	domain, Protein
B5T_02282	COG2010	Cytochrome c
B5T_02285	COG3278	Belongs to the heme-copper respiratory oxidase family
B5T_02286	COG4774	siderophore transport
B5T_02287	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_02289	COG1846	Transcriptional regulator
B5T_02293	COG1335	isochorismatase
B5T_02294	COG3473	Maleate cis-trans isomerase
B5T_02295	COG0596	Alpha beta hydrolase
B5T_02296	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B5T_02297	COG2309	aminopeptidase activity
B5T_02298	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B5T_02298	COG2010	Cytochrome c
B5T_02299	COG2080	2 iron, 2 sulfur cluster binding
B5T_02300	COG2010	Cytochrome c
B5T_02300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B5T_02302	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B5T_02308	COG0583	DNA-binding transcription factor activity
B5T_02309	COG0583	DNA-binding transcription factor activity
B5T_02310	COG2814	Major facilitator Superfamily
B5T_02313	COG0330	HflC and HflK could
B5T_02314	COG0697	spore germination
B5T_02316	COG0542	response to heat
B5T_02319	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B5T_02321	COG0180	Tryptophanyl-tRNA synthetase
B5T_02322	COG0009	L-threonylcarbamoyladenylate synthase
B5T_02323	COG0613	PHP domain protein
B5T_02324	COG2917	probably involved in intracellular septation
B5T_02325	COG2350	Protein conserved in bacteria
B5T_02328	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_02329	COG0204	Acyl-transferase
B5T_02333	COG4181	ATPase activity
B5T_02335	COG2814	Major facilitator Superfamily
B5T_02338	COG1070	Carbohydrate kinase
B5T_02339	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B5T_02340	COG0277	FAD linked oxidase domain protein
B5T_02341	COG2885	chlorophyll binding
B5T_02346	COG3243	poly(R)-hydroxyalkanoic acid synthase
B5T_02347	COG3339	Conserved Protein
B5T_02348	COG1192	Involved in chromosome partitioning
B5T_02351	COG0069	glutamate synthase activity
B5T_02352	COG0741	lytic transglycosylase activity
B5T_02352	COG1196	nuclear chromosome segregation
B5T_02352	COG0739	heme binding
B5T_02355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B5T_02357	COG2079	MmgE PrpD family protein
B5T_02359	COG2852	Protein conserved in bacteria
B5T_02361	COG0372	Belongs to the citrate synthase family
B5T_02362	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B5T_02363	COG1802	Transcriptional regulator
B5T_02366	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B5T_02367	COG0328	RNA-DNA hybrid ribonuclease activity
B5T_02369	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_02370	COG0741	lytic transglycosylase activity
B5T_02370	COG1388	LysM domain
B5T_02371	COG4166	transmembrane transport
B5T_02372	COG4174	ABC transporter (Permease)
B5T_02373	COG4239	(ABC) transporter, permease
B5T_02374	COG4172	Belongs to the ABC transporter superfamily
B5T_02376	COG0737	Belongs to the 5'-nucleotidase family
B5T_02377	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B5T_02379	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B5T_02380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B5T_02381	COG0740	serine-type endopeptidase activity
B5T_02382	COG0544	peptidyl-prolyl cis-trans isomerase activity
B5T_02383	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B5T_02386	COG1289	transmembrane transporter activity
B5T_02388	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5T_02391	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B5T_02394	COG1309	transcriptional regulator
B5T_02396	COG2814	Major facilitator Superfamily
B5T_02398	COG2814	Major facilitator Superfamily
B5T_02412	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B5T_02419	COG1643	Atp-dependent helicase
B5T_02422	COG0625	glutathione transferase activity
B5T_02423	COG0583	DNA-binding transcription factor activity
B5T_02427	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B5T_02431	COG0271	Belongs to the BolA IbaG family
B5T_02434	COG0039	L-malate dehydrogenase activity
B5T_02435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B5T_02436	COG0702	epimerase
B5T_02439	COG1960	acyl-CoA dehydrogenase activity
B5T_02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B5T_02441	COG1024	Enoyl-CoA hydratase
B5T_02443	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_02445	COG0824	Thioesterase
B5T_02450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B5T_02452	COG0587	DNA-directed DNA polymerase activity
B5T_02454	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5T_02456	COG0589	response to stress
B5T_02457	COG0659	secondary active sulfate transmembrane transporter activity
B5T_02460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B5T_02461	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B5T_02463	COG2853	Lipoprotein
B5T_02465	COG3220	belongs to the UPF0276 family
B5T_02467	COG1309	transcriptional regulator
B5T_02469	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02470	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02471	COG1960	acyl-CoA dehydrogenase activity
B5T_02472	COG1024	Enoyl-CoA hydratase
B5T_02473	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_02482	COG1643	Atp-dependent helicase
B5T_02485	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
B5T_02490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5T_02492	COG2271	Major facilitator Superfamily
B5T_02494	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B5T_02496	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B5T_02498	COG2205	protein histidine kinase activity
B5T_02503	COG1021	2,3-dihydroxybenzoate-AMP ligase
B5T_02508	COG3321	synthase
B5T_02508	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_02508	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B5T_02508	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5T_02509	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5T_02512	COG3433	isochorismatase activity
B5T_02512	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_02512	COG2226	methyltransferase
B5T_02513	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_02515	COG1131	(ABC) transporter
B5T_02517	COG4771	TonB-dependent receptor
B5T_02518	COG4771	TonB-dependent receptor
B5T_02524	COG2311	Membrane
B5T_02527	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B5T_02528	COG4771	TonB-dependent receptor
B5T_02529	COG1429	ligase activity, forming nitrogen-metal bonds
B5T_02533	COG2356	endonuclease I
B5T_02534	COG1802	Transcriptional regulator
B5T_02538	COG2801	Transposase and inactivated derivatives
B5T_02548	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B5T_02551	COG0535	radical SAM domain protein
B5T_02554	COG0625	glutathione transferase activity
B5T_02560	COG5002	protein histidine kinase activity
B5T_02571	COG3501	Rhs element vgr protein
B5T_02572	COG2186	Transcriptional regulator
B5T_02573	COG1620	l-lactate permease
B5T_02574	COG0247	lactate metabolic process
B5T_02584	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
B5T_02599	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5T_02602	COG4574	serine-type endopeptidase inhibitor activity
B5T_02606	COG2433	Pfam Transposase IS66
B5T_02611	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B5T_02613	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
B5T_02614	COG3622	Belongs to the hyi family
B5T_02615	COG0672	)-iron permease
B5T_02617	COG0436	Aminotransferase
B5T_02619	COG0501	Belongs to the peptidase M48B family
B5T_02620	COG0745	RESPONSE REGULATOR receiver
B5T_02620	COG3706	GGDEF domain
B5T_02625	COG0714	Associated with various cellular activities
B5T_02628	COG1286	toxin biosynthetic process
B5T_02630	COG0285	dihydrofolate synthase activity
B5T_02631	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B5T_02632	COG0159	tryptophan synthase activity
B5T_02633	COG0133	tryptophan synthase activity
B5T_02634	COG0135	phosphoribosylanthranilate isomerase activity
B5T_02635	COG0101	tRNA pseudouridine synthase activity
B5T_02637	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B5T_02639	COG0473	3-isopropylmalate dehydrogenase activity
B5T_02640	COG0066	3-isopropylmalate dehydratase activity
B5T_02641	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B5T_02643	COG2801	Transposase and inactivated derivatives
B5T_02645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B5T_02649	COG1301	dicarboxylic acid transport
B5T_02652	COG3268	Saccharopine dehydrogenase
B5T_02654	COG3712	iron ion homeostasis
B5T_02660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B5T_02661	COG1522	sequence-specific DNA binding
B5T_02662	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B5T_02664	COG0708	Exodeoxyribonuclease III
B5T_02667	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B5T_02668	COG0326	Molecular chaperone. Has ATPase activity
B5T_02669	COG1090	epimerase
B5T_02674	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5T_02677	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B5T_02679	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B5T_02680	COG0045	succinate-CoA ligase (ADP-forming) activity
B5T_02685	COG1053	succinate dehydrogenase
B5T_02686	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B5T_02687	COG2009	succinate dehydrogenase
B5T_02692	COG2084	Dehydrogenase
B5T_02696	COG0579	oxidoreductase
B5T_02698	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_02701	COG1305	Transglutaminase-like
B5T_02703	COG2308	Evidence 4 Homologs of previously reported genes of
B5T_02708	COG0583	DNA-binding transcription factor activity
B5T_02709	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_02709	COG3153	acetyltransferase
B5T_02711	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B5T_02712	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B5T_02714	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_02715	COG2146	nitrite reductase [NAD(P)H] activity
B5T_02716	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_02716	COG2146	nitrite reductase [NAD(P)H] activity
B5T_02722	COG1322	Protein conserved in bacteria
B5T_02723	COG0084	hydrolase, TatD family'
B5T_02726	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B5T_02727	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B5T_02728	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B5T_02729	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B5T_02730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5T_02733	COG0416	fatty acid biosynthetic process
B5T_02734	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B5T_02736	COG0424	maF-like protein
B5T_02738	COG0546	phosphoglycolate phosphatase activity
B5T_02739	COG0564	pseudouridine synthase activity
B5T_02740	COG1530	ribonuclease E activity
B5T_02742	COG4804	nuclease activity
B5T_02743	COG2003	Belongs to the UPF0758 family
B5T_02750	COG5489	Protein of unknown function (DUF736)
B5T_02758	COG1192	Involved in chromosome partitioning
B5T_02764	COG0583	DNA-binding transcription factor activity
B5T_02765	COG3384	dioxygenase
B5T_02766	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B5T_02770	COG2207	Transcriptional regulator
B5T_02771	COG0667	Aldo Keto reductase
B5T_02774	COG4584	PFAM Integrase catalytic
B5T_02775	COG1484	DNA-dependent DNA replication
B5T_02776	COG2378	regulation of single-species biofilm formation
B5T_02778	COG0583	DNA-binding transcription factor activity
B5T_02780	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02787	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B5T_02788	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02790	COG0300	oxidoreductase activity
B5T_02793	COG0583	DNA-binding transcription factor activity
B5T_02797	COG4962	Type ii secretion system protein e
B5T_02798	COG3838	Conjugal transfer protein Trbc
B5T_02800	COG3451	type IV secretory pathway VirB4
B5T_02803	COG3846	protein secretion by the type IV secretion system
B5T_02806	COG2948	multi-organism process
B5T_02808	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B5T_02809	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B5T_02810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B5T_02811	COG1663	tetraacyldisaccharide 4'-kinase activity
B5T_02812	COG1132	(ABC) transporter
B5T_02813	COG0848	biopolymer transport protein
B5T_02814	COG0811	peptide transport
B5T_02815	COG0658	competence protein
B5T_02815	COG2333	competence protein COMEC
B5T_02817	COG3101	peptidyl-lysine hydroxylation
B5T_02828	COG2223	nitrite transmembrane transporter activity
B5T_02829	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
B5T_02830	COG0788	formyltetrahydrofolate deformylase activity
B5T_02831	COG2207	Transcriptional regulator
B5T_02834	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_02835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_02836	COG1116	anion transmembrane transporter activity
B5T_02839	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_02840	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B5T_02841	COG4771	TonB-dependent receptor
B5T_02843	COG0314	molybdopterin synthase activity
B5T_02844	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B5T_02849	COG1024	Enoyl-CoA hydratase
B5T_02851	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_02853	COG0028	Belongs to the TPP enzyme family
B5T_02854	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_02857	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_02858	COG1304	FMN binding
B5T_02861	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B5T_02865	COG1012	belongs to the aldehyde dehydrogenase family
B5T_02866	COG0583	DNA-binding transcription factor activity
B5T_02867	COG0163	prenyltransferase activity
B5T_02878	COG4774	siderophore transport
B5T_02879	COG3712	iron ion homeostasis
B5T_02884	COG1024	Enoyl-CoA hydratase
B5T_02886	COG1960	acyl-CoA dehydrogenase activity
B5T_02891	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5T_02891	COG1042	CoA-binding domain protein
B5T_02891	COG0045	succinate-CoA ligase (ADP-forming) activity
B5T_02896	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_02901	COG2144	transferase activity, transferring acyl groups
B5T_02904	COG2193	ferroxidase activity
B5T_02905	COG1024	Enoyl-CoA hydratase
B5T_02905	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_02906	COG0183	Belongs to the thiolase family
B5T_02908	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B5T_02910	COG2840	Smr protein MutS2
B5T_02911	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B5T_02912	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B5T_02914	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B5T_02915	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B5T_02918	COG0717	Belongs to the dCTP deaminase family
B5T_02919	COG0489	protein tyrosine kinase activity
B5T_02922	COG0450	alkyl hydroperoxide reductase
B5T_02923	COG0583	DNA-binding transcription factor activity
B5T_02924	COG1064	alcohol dehydrogenase
B5T_02930	COG3042	response to heat
B5T_02934	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B5T_02938	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B5T_02940	COG3383	formate dehydrogenase (NAD+) activity
B5T_02943	COG2005	Transcriptional regulator
B5T_02943	COG3585	molybdate ion transport
B5T_02945	COG1793	dna ligase
B5T_02946	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B5T_02947	COG2813	Specifically methylates the guanine in position
B5T_02948	COG0741	lytic transglycosylase activity
B5T_02957	COG5002	protein histidine kinase activity
B5T_02957	COG2205	protein histidine kinase activity
B5T_02957	COG0784	Response regulator, receiver
B5T_02958	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5T_02958	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5T_02960	COG4657	Part of a membrane complex involved in electron transport
B5T_02961	COG2878	Part of a membrane complex involved in electron transport
B5T_02962	COG4656	Part of a membrane complex involved in electron transport
B5T_02963	COG4658	electron transport chain
B5T_02964	COG4659	FMN binding
B5T_02965	COG4660	Part of a membrane complex involved in electron transport
B5T_02967	COG0786	glutamate:sodium symporter activity
B5T_02968	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B5T_02969	COG1596	polysaccharide export
B5T_02969	COG1555	photosystem II stabilization
B5T_02970	COG0284	orotidine-5'-phosphate decarboxylase activity
B5T_02971	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
B5T_02973	COG0776	regulation of translation
B5T_02975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B5T_02976	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B5T_02977	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5T_02978	COG0077	Prephenate dehydratase
B5T_02978	COG1605	Chorismate mutase
B5T_02979	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B5T_02981	COG0402	S-adenosylhomocysteine deaminase activity
B5T_02982	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_02983	COG0546	phosphoglycolate phosphatase activity
B5T_02984	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_02994	COG2226	methyltransferase
B5T_02997	COG2983	Belongs to the UPF0260 family
B5T_02998	COG3100	YcgL domain-containing protein
B5T_02999	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
B5T_03000	COG0588	phosphoglycerate mutase activity
B5T_03001	COG5380	lipid catabolic process
B5T_03003	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B5T_03005	COG1960	acyl-CoA dehydrogenase activity
B5T_03006	COG1454	alcohol dehydrogenase
B5T_03007	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B5T_03008	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B5T_03015	COG1695	Transcriptional regulator
B5T_03019	COG0427	acetyl-CoA hydrolase
B5T_03022	COG1136	(ABC) transporter
B5T_03025	COG0418	dihydroorotase activity
B5T_03030	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03032	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03033	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B5T_03034	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_03037	COG1609	Transcriptional regulator
B5T_03039	COG0583	DNA-binding transcription factor activity
B5T_03040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B5T_03041	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_03045	COG2070	2-Nitropropane dioxygenase
B5T_03046	COG3189	MarR family transcriptional regulator
B5T_03047	COG4890	Cyd operon protein YbgT
B5T_03048	COG1294	oxidase, subunit
B5T_03050	COG4988	ABC transporter
B5T_03051	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B5T_03056	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B5T_03058	COG2223	nitrite transmembrane transporter activity
B5T_03059	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B5T_03060	COG1140	nitrate reductase beta subunit
B5T_03061	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B5T_03062	COG2181	nitrate reductase activity
B5T_03066	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_03068	COG3094	Invasion gene expression up-regulator, SirB
B5T_03069	COG1959	2 iron, 2 sulfur cluster binding
B5T_03070	COG1959	2 iron, 2 sulfur cluster binding
B5T_03074	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B5T_03076	COG0840	transmembrane signaling receptor activity
B5T_03087	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B5T_03089	COG2851	Citrate transporter
B5T_03091	COG0066	3-isopropylmalate dehydratase activity
B5T_03092	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B5T_03094	COG3180	Ammonia monooxygenase
B5T_03095	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B5T_03096	COG0527	aspartate kinase activity
B5T_03097	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B5T_03100	COG2137	regulation of response to DNA damage stimulus
B5T_03102	COG1546	Belongs to the CinA family
B5T_03109	COG3586	endonuclease activity
B5T_03110	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B5T_03115	COG0732	type I restriction modification DNA specificity domain
B5T_03116	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
B5T_03125	COG4771	TonB-dependent receptor
B5T_03127	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B5T_03128	COG1309	transcriptional regulator
B5T_03131	COG1024	Enoyl-CoA hydratase
B5T_03133	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03134	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B5T_03135	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B5T_03144	COG1509	lysine 2,3-aminomutase activity
B5T_03145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5T_03147	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B5T_03148	COG1074	ATP-dependent DNA helicase activity
B5T_03149	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5T_03152	COG3784	Protein of unknown function (DUF1318)
B5T_03173	COG2433	Pfam Transposase IS66
B5T_03175	COG3039	Transposase
B5T_03184	COG2003	Belongs to the UPF0758 family
B5T_03198	COG0776	regulation of translation
B5T_03200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B5T_03201	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B5T_03202	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B5T_03203	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B5T_03206	COG0583	DNA-binding transcription factor activity
B5T_03210	COG1271	oxidase subunit
B5T_03211	COG1294	oxidase, subunit
B5T_03212	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B5T_03213	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B5T_03215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B5T_03217	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B5T_03219	COG0425	Belongs to the sulfur carrier protein TusA family
B5T_03220	COG4783	chaperone-mediated protein folding
B5T_03221	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B5T_03222	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B5T_03223	COG0602	queuosine metabolic process
B5T_03226	COG0823	Involved in the tonB-independent uptake of proteins
B5T_03230	COG0824	Thioesterase
B5T_03231	COG2255	four-way junction helicase activity
B5T_03232	COG0632	four-way junction helicase activity
B5T_03233	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
B5T_03234	COG0217	transcriptional regulatory protein
B5T_03235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B5T_03239	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
B5T_03240	COG0729	surface antigen
B5T_03243	COG0442	prolyl-tRNA aminoacylation
B5T_03245	COG1192	Involved in chromosome partitioning
B5T_03246	COG1960	acyl-CoA dehydrogenase activity
B5T_03247	COG1309	transcriptional regulator
B5T_03250	COG0514	ATP-dependent DNA helicase (RecQ)
B5T_03252	COG0513	Belongs to the DEAD box helicase family
B5T_03253	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03261	COG0189	ligase activity
B5T_03262	COG0189	ligase activity
B5T_03262	COG4067	protein conserved in archaea
B5T_03263	COG0137	argininosuccinate synthase activity
B5T_03264	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B5T_03265	COG0450	alkyl hydroperoxide reductase
B5T_03269	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B5T_03270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B5T_03271	COG3842	ATPase activity
B5T_03272	COG3706	GGDEF domain
B5T_03272	COG0745	RESPONSE REGULATOR receiver
B5T_03273	COG3706	GGDEF domain
B5T_03274	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B5T_03275	COG2205	protein histidine kinase activity
B5T_03276	COG0745	RESPONSE REGULATOR receiver
B5T_03277	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B5T_03277	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5T_03278	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5T_03293	COG1012	belongs to the aldehyde dehydrogenase family
B5T_03294	COG3384	dioxygenase
B5T_03296	COG3971	2-oxopent-4-enoate hydratase activity
B5T_03298	COG1012	belongs to the aldehyde dehydrogenase family
B5T_03299	COG1846	Transcriptional regulator
B5T_03300	COG0683	leucine binding
B5T_03301	COG0861	Integral membrane protein TerC family
B5T_03304	COG0601	transmembrane transport
B5T_03306	COG0444	Belongs to the ABC transporter superfamily
B5T_03307	COG4608	Belongs to the ABC transporter superfamily
B5T_03308	COG0747	negative chemotaxis
B5T_03314	COG0655	NAD(P)H dehydrogenase (quinone) activity
B5T_03320	COG0705	Rhomboid family
B5T_03322	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B5T_03325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_03326	COG0402	S-adenosylhomocysteine deaminase activity
B5T_03328	COG1335	isochorismatase
B5T_03330	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03331	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B5T_03332	COG1116	anion transmembrane transporter activity
B5T_03337	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B5T_03341	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B5T_03342	COG1611	Belongs to the LOG family
B5T_03345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B5T_03346	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
B5T_03352	COG0735	belongs to the Fur family
B5T_03353	COG0523	cobalamin synthesis protein
B5T_03354	COG1960	acyl-CoA dehydrogenase activity
B5T_03355	COG0583	DNA-binding transcription factor activity
B5T_03356	COG2814	Major facilitator Superfamily
B5T_03358	COG2249	NAD(P)H dehydrogenase (quinone) activity
B5T_03359	COG0583	DNA-binding transcription factor activity
B5T_03372	COG0183	Belongs to the thiolase family
B5T_03374	COG4993	Dehydrogenase
B5T_03379	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B5T_03381	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03383	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B5T_03384	COG1191	sigma factor activity
B5T_03391	COG0745	RESPONSE REGULATOR receiver
B5T_03392	COG0840	transmembrane signaling receptor activity
B5T_03393	COG2201	protein-glutamate methylesterase activity
B5T_03394	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B5T_03395	COG0840	transmembrane signaling receptor activity
B5T_03397	COG0835	chemotaxis
B5T_03398	COG2198	Histidine kinase
B5T_03398	COG0643	Histidine kinase
B5T_03399	COG1360	Flagellar Motor Protein
B5T_03407	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B5T_03414	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B5T_03419	COG1580	Controls the rotational direction of flagella during chemotaxis
B5T_03424	COG1987	bacterial-type flagellum assembly
B5T_03426	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B5T_03427	COG1256	bacterial-type flagellum assembly
B5T_03429	COG1706	bacterial-type flagellum-dependent cell motility
B5T_03431	COG4786	Flagellar basal body rod
B5T_03433	COG1749	Flagellar hook protein flgE
B5T_03434	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B5T_03435	COG1558	bacterial-type flagellum-dependent cell motility
B5T_03440	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B5T_03444	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B5T_03449	COG0459	protein refolding
B5T_03450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B5T_03452	COG2211	Major facilitator Superfamily
B5T_03453	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B5T_03454	COG2096	Adenosyltransferase
B5T_03455	COG2205	protein histidine kinase activity
B5T_03456	COG0745	RESPONSE REGULATOR receiver
B5T_03463	COG1115	amino acid carrier protein
B5T_03471	COG4969	Belongs to the N-Me-Phe pilin family
B5T_03474	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B5T_03475	COG0237	dephospho-CoA kinase activity
B5T_03476	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B5T_03478	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B5T_03479	COG0653	protein targeting
B5T_03480	COG0739	heme binding
B5T_03482	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
B5T_03485	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B5T_03486	COG1181	Belongs to the D-alanine--D-alanine ligase family
B5T_03487	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B5T_03488	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B5T_03489	COG0772	Belongs to the SEDS family
B5T_03490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B5T_03491	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B5T_03492	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B5T_03493	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B5T_03496	COG0275	rRNA processing
B5T_03497	COG2001	Belongs to the MraZ family
B5T_03499	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B5T_03501	COG0792	nuclease activity
B5T_03511	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03512	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03514	COG3119	arylsulfatase activity
B5T_03515	COG2969	positive regulation of protein catabolic process
B5T_03516	COG0625	glutathione transferase activity
B5T_03517	COG2857	Cytochrome c1
B5T_03518	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B5T_03519	COG0723	plastoquinol--plastocyanin reductase activity
B5T_03520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B5T_03521	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B5T_03522	COG0667	Aldo Keto reductase
B5T_03523	COG1309	transcriptional regulator
B5T_03526	COG1802	Transcriptional regulator
B5T_03528	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_03530	COG0411	ABC transporter
B5T_03532	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03533	COG1960	acyl-CoA dehydrogenase activity
B5T_03551	COG3657	addiction module killer protein
B5T_03552	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5T_03555	COG2067	long-chain fatty acid transport protein
B5T_03556	COG1960	acyl-CoA dehydrogenase activity
B5T_03557	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B5T_03558	COG2945	thiolester hydrolase activity
B5T_03560	COG2046	Belongs to the sulfate adenylyltransferase family
B5T_03561	COG1597	lipid kinase activity
B5T_03563	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5T_03565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B5T_03566	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B5T_03567	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B5T_03568	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B5T_03569	COG5007	Belongs to the BolA IbaG family
B5T_03573	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B5T_03576	COG1137	ATPase activity
B5T_03577	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B5T_03580	COG1660	Displays ATPase and GTPase activities
B5T_03583	COG0443	Heat shock 70 kDa protein
B5T_03585	COG0312	modulator of DNA gyrase
B5T_03586	COG3028	Belongs to the UPF0307 family
B5T_03587	COG2807	transmembrane transport
B5T_03588	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5T_03588	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5T_03589	COG0312	modulator of DNA gyrase
B5T_03590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B5T_03592	COG0424	maF-like protein
B5T_03593	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B5T_03594	COG1792	Involved in formation and maintenance of cell shape
B5T_03595	COG1077	Cell shape determining protein MreB Mrl
B5T_03596	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B5T_03597	COG0154	amidase activity
B5T_03598	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B5T_03601	COG1024	Enoyl-CoA hydratase
B5T_03604	COG3501	Rhs element vgr protein
B5T_03615	COG3038	cytochrome b561
B5T_03619	COG2205	protein histidine kinase activity
B5T_03620	COG2197	response regulator
B5T_03623	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B5T_03624	COG2890	protein-(glutamine-N5) methyltransferase activity
B5T_03625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B5T_03626	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B5T_03628	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B5T_03629	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B5T_03631	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B5T_03632	COG2801	Transposase and inactivated derivatives
B5T_03634	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B5T_03635	COG0193	aminoacyl-tRNA hydrolase activity
B5T_03637	COG0012	GTP binding
B5T_03639	COG2068	MobA-Related Protein
B5T_03640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B5T_03651	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B5T_03655	COG0697	spore germination
B5T_03657	COG0438	transferase activity, transferring glycosyl groups
B5T_03660	COG0438	transferase activity, transferring glycosyl groups
B5T_03663	COG3436	PFAM IS66 Orf2 family protein
B5T_03665	COG1045	serine acetyltransferase
B5T_03666	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
B5T_03668	COG1012	belongs to the aldehyde dehydrogenase family
B5T_03669	COG0473	3-isopropylmalate dehydrogenase activity
B5T_03672	COG0154	amidase activity
B5T_03673	COG0436	Aminotransferase
B5T_03675	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B5T_03676	COG1862	Preprotein translocase
B5T_03677	COG0343	queuine tRNA-ribosyltransferase activity
B5T_03678	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B5T_03681	COG0795	lipopolysaccharide-transporting ATPase activity
B5T_03682	COG0795	lipopolysaccharide-transporting ATPase activity
B5T_03683	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B5T_03685	COG0525	valine-tRNA ligase activity
B5T_03688	COG1597	lipid kinase activity
B5T_03692	COG2433	Pfam Transposase IS66
B5T_03693	COG1183	phosphatidylcholine synthase activity
B5T_03694	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B5T_03695	COG0583	DNA-binding transcription factor activity
B5T_03697	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03700	COG0028	Belongs to the TPP enzyme family
B5T_03719	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B5T_03720	COG1047	Peptidyl-prolyl cis-trans
B5T_03721	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B5T_03722	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B5T_03723	COG0196	riboflavin kinase activity
B5T_03724	COG0728	peptidoglycan biosynthetic process
B5T_03725	COG0268	Binds directly to 16S ribosomal RNA
B5T_03726	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B5T_03727	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B5T_03728	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B5T_03729	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B5T_03730	COG0142	geranyltranstransferase activity
B5T_03737	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03744	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B5T_03747	COG4221	oxidoreductase activity
B5T_03748	COG2267	carboxylic ester hydrolase activity
B5T_03760	COG2814	Major facilitator Superfamily
B5T_03767	COG0659	secondary active sulfate transmembrane transporter activity
B5T_03769	COG0203	ribosomal protein L17
B5T_03770	COG0202	RNA polymerase activity
B5T_03771	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B5T_03772	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B5T_03773	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B5T_03774	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B5T_03776	COG0200	Binds to the 23S rRNA
B5T_03777	COG1841	ribosomal large subunit assembly
B5T_03778	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B5T_03779	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B5T_03780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B5T_03781	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B5T_03782	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B5T_03783	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B5T_03784	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B5T_03785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B5T_03786	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B5T_03787	COG0255	Belongs to the universal ribosomal protein uL29 family
B5T_03788	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B5T_03789	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B5T_03790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B5T_03791	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B5T_03792	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B5T_03793	COG0089	rRNA binding
B5T_03794	COG0088	Forms part of the polypeptide exit tunnel
B5T_03795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B5T_03796	COG0051	transcription antitermination factor activity, RNA binding
B5T_03797	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B5T_03798	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B5T_03799	COG0049	tRNA binding
B5T_03800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B5T_03801	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B5T_03802	COG0085	RNA polymerase activity
B5T_03803	COG0222	ribosome binding
B5T_03804	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B5T_03805	COG0081	regulation of translation
B5T_03806	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B5T_03809	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B5T_03811	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B5T_03816	COG2433	Pfam Transposase IS66
B5T_03817	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B5T_03818	COG0739	heme binding
B5T_03819	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B5T_03821	COG0316	Belongs to the HesB IscA family
B5T_03826	COG0351	phosphomethylpyrimidine kinase
B5T_03826	COG0352	thiamine-phosphate diphosphorylase activity
B5T_03826	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B5T_03827	COG0352	thiamine-phosphate diphosphorylase activity
B5T_03828	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B5T_03831	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5T_03832	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B5T_03835	COG1489	DNA binding
B5T_03837	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B5T_03838	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B5T_03842	COG0617	tRNA 3'-terminal CCA addition
B5T_03844	COG1428	Deoxynucleoside kinase
B5T_03845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B5T_03846	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B5T_03847	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B5T_03848	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B5T_03850	COG2814	Major facilitator Superfamily
B5T_03853	COG2056	Na+-H+ antiporter family
B5T_03854	COG1185	polyribonucleotide nucleotidyltransferase activity
B5T_03855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B5T_03856	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B5T_03857	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B5T_03858	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B5T_03859	COG2251	uridine kinase activity
B5T_03859	COG0195	Participates in both transcription termination and antitermination
B5T_03860	COG0779	Required for maturation of 30S ribosomal subunits
B5T_03862	COG0149	triose-phosphate isomerase activity
B5T_03863	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B5T_03864	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B5T_03865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B5T_03866	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
B5T_03868	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_03869	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B5T_03870	COG0505	Belongs to the CarA family
B5T_03871	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B5T_03872	COG0484	heat shock protein binding
B5T_03873	COG0443	Heat shock 70 kDa protein
B5T_03874	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B5T_03875	COG1420	regulation of RNA biosynthetic process
B5T_03876	COG0497	DNA recombination
B5T_03879	COG2914	Belongs to the UPF0125 (RnfH) family
B5T_03880	COG0733	neurotransmitter:sodium symporter activity
B5T_03881	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B5T_03885	COG0667	Aldo Keto reductase
B5T_03886	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03887	COG0583	DNA-binding transcription factor activity
B5T_03893	COG0154	amidase activity
B5T_03899	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_03906	COG2807	transmembrane transport
B5T_03909	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_03910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_03912	COG0402	S-adenosylhomocysteine deaminase activity
B5T_03913	COG3648	Uricase
B5T_03913	COG3195	allantoin biosynthetic process
B5T_03917	COG4266	Belongs to the allantoicase family
B5T_03918	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B5T_03921	COG0583	DNA-binding transcription factor activity
B5T_03924	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_03926	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_03927	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_03929	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B5T_03930	COG3964	amidohydrolase
B5T_03932	COG1414	Transcriptional regulator
B5T_03936	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5T_03938	COG0505	Belongs to the CarA family
B5T_03940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B5T_03941	COG1522	sequence-specific DNA binding
B5T_03942	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_03943	COG1309	transcriptional regulator
B5T_03947	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_03948	COG1024	Enoyl-CoA hydratase
B5T_03953	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B5T_03954	COG2226	methyltransferase
B5T_03956	COG0596	Alpha beta hydrolase
B5T_03957	COG0156	8-amino-7-oxononanoate synthase activity
B5T_03958	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B5T_03960	COG2045	Belongs to the ComB family
B5T_03964	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B5T_03965	COG0493	'glutamate synthase
B5T_03966	COG0067	glutamate synthase
B5T_03966	COG0069	glutamate synthase activity
B5T_03966	COG0070	glutamate synthase
B5T_03968	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B5T_03969	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B5T_03981	COG1137	ATPase activity
B5T_03986	COG0281	malic enzyme
B5T_03987	COG0254	rRNA binding
B5T_03988	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B5T_03989	COG0477	Major facilitator Superfamily
B5T_03990	COG1566	PFAM secretion protein HlyD family protein
B5T_03991	COG0018	arginyl-trna synthetase
B5T_03993	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B5T_03994	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B5T_03995	COG0129	dihydroxy-acid dehydratase activity
B5T_03997	COG1012	belongs to the aldehyde dehydrogenase family
B5T_03998	COG1454	alcohol dehydrogenase
B5T_04001	COG0543	2 iron, 2 sulfur cluster binding
B5T_04001	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B5T_04002	COG2995	paraquat-inducible protein a
B5T_04003	COG3008	intermembrane lipid transfer
B5T_04003	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B5T_04008	COG0181	hydroxymethylbilane synthase activity
B5T_04010	COG3275	phosphorelay sensor kinase activity
B5T_04011	COG0165	Argininosuccinate lyase
B5T_04014	COG4774	siderophore transport
B5T_04016	COG1595	DNA-templated transcription, initiation
B5T_04021	COG3712	iron ion homeostasis
B5T_04022	COG1595	DNA-templated transcription, initiation
B5T_04023	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B5T_04024	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_04027	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B5T_04028	COG2267	carboxylic ester hydrolase activity
B5T_04031	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B5T_04033	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B5T_04035	COG3098	single-species biofilm formation
B5T_04036	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
B5T_04038	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B5T_04041	COG0248	Ppx GppA phosphatase
B5T_04044	COG1335	isochorismatase
B5T_04045	COG0583	DNA-binding transcription factor activity
B5T_04047	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B5T_04052	COG2205	protein histidine kinase activity
B5T_04053	COG0745	RESPONSE REGULATOR receiver
B5T_04054	COG3268	Saccharopine dehydrogenase
B5T_04058	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B5T_04059	COG2186	Transcriptional regulator
B5T_04060	COG0154	amidase activity
B5T_04061	COG0604	alcohol dehydrogenase
B5T_04062	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04065	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B5T_04070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B5T_04071	COG1595	DNA-templated transcription, initiation
B5T_04079	COG0789	Transcriptional regulator
B5T_04080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B5T_04081	COG3384	dioxygenase
B5T_04083	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B5T_04086	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5T_04091	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B5T_04091	COG2169	Transcriptional regulator
B5T_04099	COG3634	alkyl hydroperoxide reductase activity
B5T_04100	COG0450	alkyl hydroperoxide reductase
B5T_04102	COG0840	transmembrane signaling receptor activity
B5T_04104	COG2132	Multicopper oxidase
B5T_04106	COG0288	reversible hydration of carbon dioxide
B5T_04107	COG1047	Peptidyl-prolyl cis-trans
B5T_04108	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04113	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04115	COG1012	belongs to the aldehyde dehydrogenase family
B5T_04116	COG1960	acyl-CoA dehydrogenase activity
B5T_04117	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_04119	COG2030	dehydratase
B5T_04121	COG4191	Histidine kinase
B5T_04122	COG4566	intracellular signal transduction
B5T_04124	COG0489	protein tyrosine kinase activity
B5T_04126	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B5T_04132	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B5T_04136	COG1959	2 iron, 2 sulfur cluster binding
B5T_04137	COG1492	cobalamin metabolic process
B5T_04140	COG1120	ATPase activity
B5T_04141	COG4139	cobalamin transport
B5T_04142	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B5T_04143	COG4206	TonB-dependent receptor
B5T_04148	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B5T_04151	COG0642	Histidine kinase
B5T_04159	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_04160	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_04161	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B5T_04164	COG0432	Pfam Uncharacterised protein family UPF0047
B5T_04165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B5T_04168	COG1166	arginine decarboxylase activity
B5T_04171	COG4221	oxidoreductase activity
B5T_04172	COG1733	regulation of RNA biosynthetic process
B5T_04177	COG1566	PFAM secretion protein HlyD family protein
B5T_04180	COG5002	protein histidine kinase activity
B5T_04182	COG3039	Transposase
B5T_04183	COG0004	ammonium transporteR
B5T_04184	COG0347	Belongs to the P(II) protein family
B5T_04185	COG2960	long-chain fatty acid transporting porin activity
B5T_04186	COG2015	COG2015, Alkyl sulfatase and related hydrolases
B5T_04188	COG0606	chelatase, subunit chli
B5T_04189	COG0697	spore germination
B5T_04191	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_04193	COG1187	pseudouridine synthase activity
B5T_04196	COG5002	protein histidine kinase activity
B5T_04198	COG0745	RESPONSE REGULATOR receiver
B5T_04201	COG1960	acyl-CoA dehydrogenase activity
B5T_04202	COG1960	acyl-CoA dehydrogenase activity
B5T_04205	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04206	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04209	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04210	COG0183	Belongs to the thiolase family
B5T_04212	COG2909	trisaccharide binding
B5T_04214	COG1024	Enoyl-CoA hydratase
B5T_04215	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_04216	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B5T_04218	COG1024	Enoyl-CoA hydratase
B5T_04219	COG1960	acyl-CoA dehydrogenase activity
B5T_04222	COG1024	Enoyl-CoA hydratase
B5T_04224	COG1024	Enoyl-CoA hydratase
B5T_04227	COG1280	lysine exporter protein (LysE YggA)
B5T_04229	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
B5T_04231	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04236	COG1515	deoxyribonuclease V activity
B5T_04244	COG1566	PFAM secretion protein HlyD family protein
B5T_04247	COG2353	YceI-like domain
B5T_04248	COG3038	cytochrome b561
B5T_04251	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_04252	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B5T_04253	COG0385	Bile acid
B5T_04254	COG0492	ferredoxin-NADP+ reductase activity
B5T_04257	COG1024	Enoyl-CoA hydratase
B5T_04260	COG0517	IMP dehydrogenase activity
B5T_04260	COG1125	glycine betaine transport
B5T_04266	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B5T_04266	COG0678	peroxiredoxin activity
B5T_04269	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_04271	COG0753	catalase activity
B5T_04272	COG1272	protein, Hemolysin III
B5T_04274	COG0386	Belongs to the glutathione peroxidase family
B5T_04280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B5T_04289	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B5T_04290	COG1320	monovalent cation:proton antiporter activity
B5T_04291	COG2212	antiporter activity
B5T_04292	COG1863	multisubunit Na H antiporter MnhE subunit
B5T_04293	COG0651	ATP synthesis coupled electron transport
B5T_04294	COG1006	Multisubunit Na H antiporter MnhC subunit
B5T_04295	COG2111	Na H antiporter
B5T_04295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B5T_04298	COG1160	GTP binding
B5T_04301	COG1960	acyl-CoA dehydrogenase activity
B5T_04302	COG1250	3-hydroxyacyl-CoA dehydrogenase
B5T_04302	COG1024	Enoyl-CoA hydratase
B5T_04304	COG5285	phytanoyl-CoA dioxygenase
B5T_04305	COG1028	Short-chain dehydrogenase reductase Sdr
B5T_04314	COG1131	(ABC) transporter
B5T_04315	COG0842	Transport permease protein
B5T_04319	COG0625	glutathione transferase activity
B5T_04320	COG0668	transmembrane transport
B5T_04321	COG0678	peroxiredoxin activity
B5T_04324	COG1666	GTP binding
B5T_04326	COG3093	addiction module antidote protein HigA
B5T_04327	COG1901	pseudouridine methyltransferase
B5T_04328	COG0500	methyltransferase
B5T_04334	COG1121	(ABC) transporter
B5T_04335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5T_04336	COG0534	Mate efflux family protein
B5T_04348	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B5T_04349	COG1773	rubredoxin
B5T_04350	COG3161	chorismate lyase activity
B5T_04351	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B5T_04354	COG2900	Belongs to the SlyX family
B5T_04355	COG1309	transcriptional regulator
B5T_04357	COG2119	membrane
B5T_04358	COG4681	YaeQ
B5T_04360	COG0431	NADPH-dependent FMN reductase
B5T_04361	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B5T_04362	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B5T_04363	COG0640	Transcriptional regulator
B5T_04365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B5T_04366	COG0581	inorganic phosphate transmembrane transporter activity
B5T_04367	COG0573	inorganic phosphate transmembrane transporter activity
B5T_04368	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B5T_04371	COG1607	acyl-coa hydrolase
B5T_04372	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
B5T_04373	COG0210	DNA helicase
B5T_04377	COG3284	Transcriptional regulator
B5T_04380	COG1012	belongs to the aldehyde dehydrogenase family
B5T_04387	COG4172	Belongs to the ABC transporter superfamily
B5T_04388	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5T_04389	COG0601	transmembrane transport
B5T_04390	COG0747	negative chemotaxis
B5T_04395	COG0824	Thioesterase
B5T_04396	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04397	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B5T_04398	COG1970	mechanosensitive ion channel activity
B5T_04399	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5T_04399	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B5T_04400	COG0737	Belongs to the 5'-nucleotidase family
B5T_04402	COG0583	DNA-binding transcription factor activity
B5T_04405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B5T_04408	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_04409	COG0559	Belongs to the binding-protein-dependent transport system permease family
B5T_04416	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B5T_04417	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B5T_04418	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B5T_04419	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B5T_04420	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B5T_04421	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B5T_04423	COG0356	it plays a direct role in the translocation of protons across the membrane
B5T_04425	COG1475	DNA binding
B5T_04426	COG1192	Involved in chromosome partitioning
B5T_04427	COG0357	Ribosomal RNA small subunit methyltransferase G
B5T_04428	COG0445	tRNA wobble uridine modification
B5T_04429	COG3263	regulation of cellular component size
B5T_04430	COG0300	oxidoreductase activity
B5T_04431	COG1960	acyl-CoA dehydrogenase activity
B5T_04432	COG0546	phosphoglycolate phosphatase activity
B5T_04434	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B5T_04435	COG1278	Cold shock
B5T_04440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B5T_04442	COG0318	PFAM AMP-dependent synthetase and ligase
B5T_04446	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B5T_04447	COG0706	membrane insertase activity
B5T_04448	COG0594	ribonuclease P activity