locus-tag	class	description
ASALC70_00003	COG0784	Response regulator, receiver
ASALC70_00003	COG5002	protein histidine kinase activity
ASALC70_00004	COG2202	Pas domain
ASALC70_00004	COG2205	protein histidine kinase activity
ASALC70_00005	COG0784	Response regulator, receiver
ASALC70_00005	COG2198	Histidine kinase
ASALC70_00005	COG5002	protein histidine kinase activity
ASALC70_00007	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASALC70_00016	COG3156	type II secretion system protein K
ASALC70_00023	COG3848	Pyruvate phosphate dikinase
ASALC70_00023	COG0574	Belongs to the PEP-utilizing enzyme family
ASALC70_00029	COG4974	Belongs to the 'phage' integrase family
ASALC70_00036	COG2813	Specifically methylates the guanine in position
ASALC70_00037	COG2813	Specifically methylates the guanine in position
ASALC70_00038	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ASALC70_00039	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ASALC70_00040	COG0235	Class ii aldolase
ASALC70_00041	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ASALC70_00048	COG0560	Phosphoserine phosphatase
ASALC70_00051	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASALC70_00052	COG1802	Transcriptional regulator
ASALC70_00053	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASALC70_00055	COG0372	Belongs to the citrate synthase family
ASALC70_00056	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASALC70_00057	COG2828	Protein conserved in bacteria
ASALC70_00058	COG2079	MmgE PrpD family protein
ASALC70_00059	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASALC70_00060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ASALC70_00063	COG1196	nuclear chromosome segregation
ASALC70_00063	COG0741	lytic transglycosylase activity
ASALC70_00063	COG0739	heme binding
ASALC70_00064	COG0069	glutamate synthase activity
ASALC70_00068	COG1192	Involved in chromosome partitioning
ASALC70_00074	COG2814	Major facilitator Superfamily
ASALC70_00075	COG2885	chlorophyll binding
ASALC70_00076	COG0277	FAD linked oxidase domain protein
ASALC70_00076	COG0277	FAD linked oxidase domain protein
ASALC70_00077	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ASALC70_00078	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASALC70_00080	COG0789	Transcriptional regulator
ASALC70_00083	COG2814	Major facilitator Superfamily
ASALC70_00086	COG4181	ATPase activity
ASALC70_00090	COG0204	Acyl-transferase
ASALC70_00091	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_00093	COG2350	Protein conserved in bacteria
ASALC70_00094	COG2917	probably involved in intracellular septation
ASALC70_00095	COG0009	L-threonylcarbamoyladenylate synthase
ASALC70_00096	COG0180	Tryptophanyl-tRNA synthetase
ASALC70_00098	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASALC70_00101	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASALC70_00103	COG0697	spore germination
ASALC70_00104	COG0330	HflC and HflK could
ASALC70_00108	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASALC70_00110	COG0840	transmembrane signaling receptor activity
ASALC70_00113	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASALC70_00117	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_00118	COG2010	Cytochrome c
ASALC70_00118	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_00119	COG2080	2 iron, 2 sulfur cluster binding
ASALC70_00120	COG2010	Cytochrome c
ASALC70_00120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_00123	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_00125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_00126	COG0596	Alpha beta hydrolase
ASALC70_00127	COG3473	Maleate cis-trans isomerase
ASALC70_00128	COG1335	isochorismatase
ASALC70_00139	COG3278	Belongs to the heme-copper respiratory oxidase family
ASALC70_00140	COG3278	Belongs to the heme-copper respiratory oxidase family
ASALC70_00141	COG3278	Belongs to the heme-copper respiratory oxidase family
ASALC70_00143	COG2010	Cytochrome c
ASALC70_00144	COG2010	Cytochrome c
ASALC70_00155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_00157	COG3022	response to hydroperoxide
ASALC70_00159	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_00160	COG0598	Magnesium transport protein CorA
ASALC70_00163	COG0700	Nucleoside recognition
ASALC70_00174	COG2267	carboxylic ester hydrolase activity
ASALC70_00175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASALC70_00176	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASALC70_00180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_00181	COG0501	Belongs to the peptidase M48B family
ASALC70_00182	COG0316	Belongs to the HesB IscA family
ASALC70_00182	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ASALC70_00183	COG0534	Mate efflux family protein
ASALC70_00185	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_00186	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_00189	COG0604	alcohol dehydrogenase
ASALC70_00190	COG0616	signal peptide processing
ASALC70_00192	COG2816	NAD+ diphosphatase activity
ASALC70_00196	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASALC70_00197	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASALC70_00198	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASALC70_00199	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_00200	COG0328	RNA-DNA hybrid ribonuclease activity
ASALC70_00202	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_00203	COG1388	LysM domain
ASALC70_00203	COG0741	lytic transglycosylase activity
ASALC70_00204	COG4166	transmembrane transport
ASALC70_00205	COG4166	transmembrane transport
ASALC70_00206	COG4174	ABC transporter (Permease)
ASALC70_00207	COG4239	(ABC) transporter, permease
ASALC70_00208	COG4172	Belongs to the ABC transporter superfamily
ASALC70_00209	COG4172	Belongs to the ABC transporter superfamily
ASALC70_00210	COG4172	Belongs to the ABC transporter superfamily
ASALC70_00213	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASALC70_00217	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASALC70_00218	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ASALC70_00219	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ASALC70_00220	COG0740	serine-type endopeptidase activity
ASALC70_00221	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASALC70_00222	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASALC70_00226	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASALC70_00230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASALC70_00233	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_00245	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASALC70_00246	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_00246	COG2010	Cytochrome c
ASALC70_00250	COG2814	Major facilitator Superfamily
ASALC70_00252	COG3119	arylsulfatase activity
ASALC70_00254	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_00255	COG2207	Transcriptional regulator
ASALC70_00256	COG0824	Thioesterase
ASALC70_00259	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASALC70_00260	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASALC70_00264	COG0587	DNA-directed DNA polymerase activity
ASALC70_00265	COG3268	Saccharopine dehydrogenase
ASALC70_00269	COG3119	arylsulfatase activity
ASALC70_00269	COG3408	Glycogen debranching enzyme
ASALC70_00274	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_00278	COG1857	crispr-associated protein
ASALC70_00284	COG1203	CRISPR-associated helicase, Cas3
ASALC70_00291	COG2308	Evidence 4 Homologs of previously reported genes of
ASALC70_00298	COG0583	DNA-binding transcription factor activity
ASALC70_00299	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_00299	COG3153	acetyltransferase
ASALC70_00300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_00300	COG3153	acetyltransferase
ASALC70_00301	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASALC70_00303	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASALC70_00305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_00306	COG0243	molybdopterin cofactor binding
ASALC70_00307	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_00308	COG2146	nitrite reductase [NAD(P)H] activity
ASALC70_00309	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_00309	COG2146	nitrite reductase [NAD(P)H] activity
ASALC70_00310	COG2223	nitrite transmembrane transporter activity
ASALC70_00312	COG2815	serine threonine protein kinase
ASALC70_00312	COG0515	serine threonine protein kinase
ASALC70_00316	COG1104	cysteine desulfurase activity
ASALC70_00319	COG2032	superoxide dismutase activity
ASALC70_00320	COG0753	catalase activity
ASALC70_00321	COG0753	catalase activity
ASALC70_00323	COG0437	4 iron, 4 sulfur cluster binding
ASALC70_00324	COG0437	4 iron, 4 sulfur cluster binding
ASALC70_00332	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASALC70_00333	COG1845	cytochrome c oxidase, subunit III
ASALC70_00335	COG0069	glutamate synthase activity
ASALC70_00337	COG4206	TonB-dependent receptor
ASALC70_00341	COG0084	hydrolase, TatD family'
ASALC70_00344	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ASALC70_00345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASALC70_00346	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASALC70_00348	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASALC70_00349	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ASALC70_00350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASALC70_00353	COG0416	fatty acid biosynthetic process
ASALC70_00354	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ASALC70_00355	COG1399	metal-binding, possibly nucleic acid-binding protein
ASALC70_00356	COG0424	maF-like protein
ASALC70_00357	COG0424	maF-like protein
ASALC70_00358	COG0616	signal peptide processing
ASALC70_00358	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASALC70_00359	COG0546	phosphoglycolate phosphatase activity
ASALC70_00361	COG1530	ribonuclease E activity
ASALC70_00364	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_00366	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASALC70_00367	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASALC70_00368	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ASALC70_00369	COG1663	tetraacyldisaccharide 4'-kinase activity
ASALC70_00370	COG1132	(ABC) transporter
ASALC70_00371	COG0848	biopolymer transport protein
ASALC70_00372	COG0811	peptide transport
ASALC70_00373	COG2333	competence protein COMEC
ASALC70_00373	COG0658	competence protein
ASALC70_00375	COG1136	(ABC) transporter
ASALC70_00379	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_00380	COG1307	EDD domain protein, DegV family
ASALC70_00382	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ASALC70_00383	COG0788	formyltetrahydrofolate deformylase activity
ASALC70_00386	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_00387	COG1131	(ABC) transporter
ASALC70_00388	COG0842	Transport permease protein
ASALC70_00389	COG3046	protein related to deoxyribodipyrimidine photolyase
ASALC70_00392	COG1301	dicarboxylic acid transport
ASALC70_00395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_00396	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_00400	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASALC70_00401	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ASALC70_00406	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASALC70_00407	COG1687	branched-chain amino acid
ASALC70_00411	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_00412	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASALC70_00413	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASALC70_00414	COG4558	Periplasmic binding protein
ASALC70_00427	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_00432	COG2144	transferase activity, transferring acyl groups
ASALC70_00435	COG1024	Enoyl-CoA hydratase
ASALC70_00435	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_00436	COG0183	Belongs to the thiolase family
ASALC70_00439	COG2840	Smr protein MutS2
ASALC70_00440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ASALC70_00442	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASALC70_00444	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASALC70_00445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ASALC70_00448	COG0717	Belongs to the dCTP deaminase family
ASALC70_00449	COG0489	protein tyrosine kinase activity
ASALC70_00453	COG0450	alkyl hydroperoxide reductase
ASALC70_00455	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASALC70_00458	COG2813	Specifically methylates the guanine in position
ASALC70_00460	COG0741	lytic transglycosylase activity
ASALC70_00463	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_00464	COG3001	Fructosamine kinase
ASALC70_00469	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ASALC70_00472	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ASALC70_00473	COG0585	pseudouridine synthase activity
ASALC70_00474	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ASALC70_00475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASALC70_00476	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ASALC70_00477	COG0148	phosphopyruvate hydratase activity
ASALC70_00478	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ASALC70_00479	COG0504	CTP synthase activity
ASALC70_00480	COG0037	tRNA processing
ASALC70_00481	COG0825	malonyl-CoA metabolic process
ASALC70_00482	COG0825	malonyl-CoA metabolic process
ASALC70_00485	COG0587	DNA-directed DNA polymerase activity
ASALC70_00486	COG0587	DNA-directed DNA polymerase activity
ASALC70_00487	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASALC70_00488	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_00489	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_00490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASALC70_00491	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ASALC70_00493	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASALC70_00495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASALC70_00496	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASALC70_00497	COG0575	Belongs to the CDS family
ASALC70_00498	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASALC70_00499	COG0233	cytoplasmic translational termination
ASALC70_00500	COG0528	UMP kinase activity
ASALC70_00501	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASALC70_00502	COG0052	Belongs to the universal ribosomal protein uS2 family
ASALC70_00504	COG0024	Methionine aminopeptidase
ASALC70_00505	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASALC70_00508	COG1393	Belongs to the ArsC family
ASALC70_00509	COG2171	N-acyltransferase activity
ASALC70_00510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASALC70_00511	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASALC70_00517	COG0742	ribosomal rna small subunit methyltransferase
ASALC70_00519	COG1968	undecaprenyl-diphosphatase activity
ASALC70_00521	COG1214	PFAM Peptidase M22, glycoprotease
ASALC70_00522	COG1199	ATP-dependent helicase activity
ASALC70_00523	COG1199	ATP-dependent helicase activity
ASALC70_00524	COG1199	ATP-dependent helicase activity
ASALC70_00527	COG2326	polyphosphate kinase activity
ASALC70_00528	COG0004	ammonium transporteR
ASALC70_00530	COG3118	belongs to the thioredoxin family
ASALC70_00531	COG1960	acyl-CoA dehydrogenase activity
ASALC70_00532	COG0850	regulation of cytokinetic process
ASALC70_00533	COG2894	cell division
ASALC70_00534	COG2894	cell division
ASALC70_00535	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ASALC70_00536	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_00547	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_00549	COG0657	acetylesterase activity
ASALC70_00554	COG0531	amino acid
ASALC70_00555	COG1254	Belongs to the acylphosphatase family
ASALC70_00556	COG1959	2 iron, 2 sulfur cluster binding
ASALC70_00556	COG1295	ribonuclease BN
ASALC70_00557	COG1393	Belongs to the ArsC family
ASALC70_00564	COG0714	Associated with various cellular activities
ASALC70_00567	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASALC70_00568	COG4771	TonB-dependent receptor
ASALC70_00570	COG1595	DNA-templated transcription, initiation
ASALC70_00572	COG3101	peptidyl-lysine hydroxylation
ASALC70_00585	COG3077	Addiction module antitoxin, RelB DinJ family
ASALC70_00593	COG0545	Peptidyl-prolyl cis-trans isomerase
ASALC70_00594	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASALC70_00609	COG0583	DNA-binding transcription factor activity
ASALC70_00615	COG0584	glycerophosphoryl diester phosphodiesterase
ASALC70_00621	COG1477	protein flavinylation
ASALC70_00622	COG2871	sodium ion transport
ASALC70_00623	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_00627	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_00628	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_00630	COG1946	Acyl-CoA thioesterase
ASALC70_00631	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASALC70_00632	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASALC70_00633	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ASALC70_00635	COG2081	HI0933 family
ASALC70_00637	COG0668	transmembrane transport
ASALC70_00638	COG1472	Belongs to the glycosyl hydrolase 3 family
ASALC70_00644	COG0589	response to stress
ASALC70_00649	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASALC70_00651	COG0084	hydrolase, TatD family'
ASALC70_00652	COG1739	Uncharacterized protein family UPF0029
ASALC70_00654	COG0556	nucleotide-excision repair
ASALC70_00655	COG0556	nucleotide-excision repair
ASALC70_00656	COG0436	Aminotransferase
ASALC70_00659	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASALC70_00661	COG1215	transferase activity, transferring glycosyl groups
ASALC70_00662	COG1215	transferase activity, transferring glycosyl groups
ASALC70_00667	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ASALC70_00668	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ASALC70_00669	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ASALC70_00671	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ASALC70_00681	COG1741	Belongs to the pirin family
ASALC70_00682	COG0427	acetyl-CoA hydrolase
ASALC70_00685	COG0418	dihydroorotase activity
ASALC70_00686	COG0418	dihydroorotase activity
ASALC70_00690	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_00692	COG4566	intracellular signal transduction
ASALC70_00693	COG4890	Cyd operon protein YbgT
ASALC70_00694	COG1294	oxidase, subunit
ASALC70_00695	COG1294	oxidase, subunit
ASALC70_00698	COG4988	ABC transporter
ASALC70_00699	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASALC70_00701	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASALC70_00702	COG0840	transmembrane signaling receptor activity
ASALC70_00705	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ASALC70_00707	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASALC70_00709	COG2137	regulation of response to DNA damage stimulus
ASALC70_00717	COG3712	iron ion homeostasis
ASALC70_00718	COG4771	TonB-dependent receptor
ASALC70_00720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASALC70_00721	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ASALC70_00728	COG1487	ribonuclease activity
ASALC70_00730	COG2814	Major facilitator Superfamily
ASALC70_00732	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ASALC70_00738	COG1569	PIN domain
ASALC70_00739	COG3311	Transcriptional regulator
ASALC70_00752	COG2132	Multicopper oxidase
ASALC70_00757	COG2132	Multicopper oxidase
ASALC70_00761	COG3077	Addiction module antitoxin, RelB DinJ family
ASALC70_00769	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASALC70_00776	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASALC70_00780	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASALC70_00781	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASALC70_00783	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ASALC70_00792	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_00793	COG1509	lysine 2,3-aminomutase activity
ASALC70_00794	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_00795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_00797	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ASALC70_00799	COG1074	ATP-dependent DNA helicase activity
ASALC70_00801	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASALC70_00805	COG3284	Transcriptional regulator
ASALC70_00806	COG3284	Transcriptional regulator
ASALC70_00807	COG3284	Transcriptional regulator
ASALC70_00811	COG1960	acyl-CoA dehydrogenase activity
ASALC70_00813	COG0776	regulation of translation
ASALC70_00814	COG0072	phenylalanine-tRNA ligase activity
ASALC70_00815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASALC70_00816	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASALC70_00817	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASALC70_00818	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ASALC70_00823	COG1271	oxidase subunit
ASALC70_00825	COG1271	oxidase subunit
ASALC70_00826	COG1294	oxidase, subunit
ASALC70_00827	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_00828	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASALC70_00829	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ASALC70_00831	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASALC70_00833	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ASALC70_00836	COG0425	Belongs to the sulfur carrier protein TusA family
ASALC70_00836	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASALC70_00837	COG4783	chaperone-mediated protein folding
ASALC70_00838	COG4773	Receptor
ASALC70_00840	COG2207	Transcriptional regulator
ASALC70_00841	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASALC70_00842	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASALC70_00845	COG0415	Belongs to the DNA photolyase family
ASALC70_00846	COG0789	Transcriptional regulator
ASALC70_00850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ASALC70_00853	COG2885	chlorophyll binding
ASALC70_00854	COG0823	Involved in the tonB-independent uptake of proteins
ASALC70_00858	COG0824	Thioesterase
ASALC70_00859	COG2255	four-way junction helicase activity
ASALC70_00860	COG0632	four-way junction helicase activity
ASALC70_00861	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASALC70_00862	COG0217	transcriptional regulatory protein
ASALC70_00863	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASALC70_00869	COG0729	surface antigen
ASALC70_00870	COG2911	Protein conserved in bacteria
ASALC70_00873	COG0442	prolyl-tRNA aminoacylation
ASALC70_00874	COG0442	prolyl-tRNA aminoacylation
ASALC70_00876	COG1192	Involved in chromosome partitioning
ASALC70_00878	COG1960	acyl-CoA dehydrogenase activity
ASALC70_00879	COG1309	transcriptional regulator
ASALC70_00881	COG0514	ATP-dependent DNA helicase (RecQ)
ASALC70_00882	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASALC70_00885	COG0513	Belongs to the DEAD box helicase family
ASALC70_00892	COG0189	ligase activity
ASALC70_00893	COG0189	ligase activity
ASALC70_00893	COG4067	protein conserved in archaea
ASALC70_00894	COG0137	argininosuccinate synthase activity
ASALC70_00895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_00896	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ASALC70_00901	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASALC70_00902	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ASALC70_00905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASALC70_00906	COG0745	RESPONSE REGULATOR receiver
ASALC70_00907	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASALC70_00907	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASALC70_00910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASALC70_00914	COG0737	Belongs to the 5'-nucleotidase family
ASALC70_00929	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_00930	COG3384	dioxygenase
ASALC70_00932	COG3971	2-oxopent-4-enoate hydratase activity
ASALC70_00934	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_00935	COG1846	Transcriptional regulator
ASALC70_00936	COG0861	Integral membrane protein TerC family
ASALC70_00950	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASALC70_00952	COG1309	transcriptional regulator
ASALC70_00958	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASALC70_00958	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_00963	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASALC70_00975	COG0412	Dienelactone hydrolase
ASALC70_00976	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASALC70_00977	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASALC70_00982	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASALC70_00984	COG1611	Belongs to the LOG family
ASALC70_00993	COG0735	belongs to the Fur family
ASALC70_00996	COG4221	oxidoreductase activity
ASALC70_00997	COG1595	DNA-templated transcription, initiation
ASALC70_00998	COG1595	DNA-templated transcription, initiation
ASALC70_01001	COG1024	Enoyl-CoA hydratase
ASALC70_01003	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_01011	COG0183	Belongs to the thiolase family
ASALC70_01013	COG4993	Dehydrogenase
ASALC70_01014	COG4993	Dehydrogenase
ASALC70_01017	COG3237	CsbD-like
ASALC70_01020	COG0589	response to stress
ASALC70_01021	COG0659	secondary active sulfate transmembrane transporter activity
ASALC70_01023	COG1191	sigma factor activity
ASALC70_01033	COG2201	protein-glutamate methylesterase activity
ASALC70_01034	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASALC70_01035	COG0840	transmembrane signaling receptor activity
ASALC70_01036	COG0835	chemotaxis
ASALC70_01037	COG0835	chemotaxis
ASALC70_01038	COG2198	Histidine kinase
ASALC70_01038	COG0643	Histidine kinase
ASALC70_01039	COG2198	Histidine kinase
ASALC70_01039	COG0643	Histidine kinase
ASALC70_01048	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASALC70_01049	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ASALC70_01057	COG1677	Flagellar hook-basal body complex protein FliE
ASALC70_01059	COG1766	The M ring may be actively involved in energy transduction
ASALC70_01060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASALC70_01070	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ASALC70_01075	COG1987	bacterial-type flagellum assembly
ASALC70_01078	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ASALC70_01080	COG3951	Flagellar rod assembly protein muramidase FlgJ
ASALC70_01080	COG1705	Flagellar rod assembly protein muramidase FlgJ
ASALC70_01081	COG1706	bacterial-type flagellum-dependent cell motility
ASALC70_01084	COG4787	bacterial-type flagellum-dependent cell motility
ASALC70_01085	COG1749	Flagellar hook protein flgE
ASALC70_01086	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ASALC70_01087	COG1558	bacterial-type flagellum-dependent cell motility
ASALC70_01092	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ASALC70_01098	COG0471	metal ion transport
ASALC70_01099	COG0471	metal ion transport
ASALC70_01100	COG0459	protein refolding
ASALC70_01101	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASALC70_01102	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_01104	COG2807	transmembrane transport
ASALC70_01106	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASALC70_01107	COG2096	Adenosyltransferase
ASALC70_01108	COG2205	protein histidine kinase activity
ASALC70_01109	COG0745	RESPONSE REGULATOR receiver
ASALC70_01118	COG1115	amino acid carrier protein
ASALC70_01129	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ASALC70_01130	COG0237	dephospho-CoA kinase activity
ASALC70_01131	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ASALC70_01134	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASALC70_01135	COG0653	protein targeting
ASALC70_01136	COG0739	heme binding
ASALC70_01138	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ASALC70_01143	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASALC70_01144	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASALC70_01145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASALC70_01146	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASALC70_01147	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ASALC70_01148	COG0772	Belongs to the SEDS family
ASALC70_01149	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASALC70_01150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASALC70_01151	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASALC70_01152	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASALC70_01157	COG0275	rRNA processing
ASALC70_01158	COG0275	rRNA processing
ASALC70_01159	COG2001	Belongs to the MraZ family
ASALC70_01160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASALC70_01160	COG0426	domain, Protein
ASALC70_01165	COG0792	nuclease activity
ASALC70_01167	COG2823	Periplasmic or secreted lipoprotein
ASALC70_01168	COG2969	positive regulation of protein catabolic process
ASALC70_01170	COG0625	glutathione transferase activity
ASALC70_01171	COG2857	Cytochrome c1
ASALC70_01172	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ASALC70_01173	COG0723	plastoquinol--plastocyanin reductase activity
ASALC70_01176	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ASALC70_01177	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASALC70_01178	COG0667	Aldo Keto reductase
ASALC70_01179	COG1233	COG1233 Phytoene dehydrogenase and related
ASALC70_01195	COG2067	long-chain fatty acid transport protein
ASALC70_01196	COG1960	acyl-CoA dehydrogenase activity
ASALC70_01197	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ASALC70_01198	COG2945	thiolester hydrolase activity
ASALC70_01200	COG2046	Belongs to the sulfate adenylyltransferase family
ASALC70_01201	COG1597	lipid kinase activity
ASALC70_01203	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASALC70_01205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASALC70_01206	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASALC70_01207	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ASALC70_01208	COG5007	Belongs to the BolA IbaG family
ASALC70_01211	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ASALC70_01214	COG1137	ATPase activity
ASALC70_01215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ASALC70_01218	COG1660	Displays ATPase and GTPase activities
ASALC70_01220	COG2239	Acts as a magnesium transporter
ASALC70_01223	COG0312	modulator of DNA gyrase
ASALC70_01224	COG3028	Belongs to the UPF0307 family
ASALC70_01225	COG2807	transmembrane transport
ASALC70_01229	COG0477	Major facilitator Superfamily
ASALC70_01231	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_01232	COG0312	modulator of DNA gyrase
ASALC70_01233	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_01237	COG0424	maF-like protein
ASALC70_01238	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ASALC70_01239	COG1792	Involved in formation and maintenance of cell shape
ASALC70_01240	COG1077	Cell shape determining protein MreB Mrl
ASALC70_01241	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASALC70_01242	COG0154	amidase activity
ASALC70_01243	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASALC70_01244	COG1024	Enoyl-CoA hydratase
ASALC70_01256	COG0848	biopolymer transport protein
ASALC70_01261	COG1595	DNA-templated transcription, initiation
ASALC70_01268	COG2890	protein-(glutamine-N5) methyltransferase activity
ASALC70_01269	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASALC70_01270	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASALC70_01272	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ASALC70_01273	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASALC70_01275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ASALC70_01276	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASALC70_01277	COG0193	aminoacyl-tRNA hydrolase activity
ASALC70_01279	COG0012	GTP binding
ASALC70_01286	COG0297	glycogen (starch) synthase activity
ASALC70_01291	COG1045	serine acetyltransferase
ASALC70_01295	COG0473	3-isopropylmalate dehydrogenase activity
ASALC70_01296	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASALC70_01298	COG0154	amidase activity
ASALC70_01299	COG0436	Aminotransferase
ASALC70_01301	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASALC70_01302	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASALC70_01303	COG1862	Preprotein translocase
ASALC70_01304	COG0343	queuine tRNA-ribosyltransferase activity
ASALC70_01305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ASALC70_01307	COG1309	transcriptional regulator
ASALC70_01308	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_01312	COG0633	Ferredoxin
ASALC70_01316	COG0657	acetylesterase activity
ASALC70_01327	COG2030	dehydratase
ASALC70_01329	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_01332	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_01334	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASALC70_01351	COG1960	acyl-CoA dehydrogenase activity
ASALC70_01352	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_01356	COG0795	lipopolysaccharide-transporting ATPase activity
ASALC70_01357	COG0795	lipopolysaccharide-transporting ATPase activity
ASALC70_01358	COG0795	lipopolysaccharide-transporting ATPase activity
ASALC70_01359	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASALC70_01361	COG0525	valine-tRNA ligase activity
ASALC70_01362	COG0525	valine-tRNA ligase activity
ASALC70_01366	COG1597	lipid kinase activity
ASALC70_01371	COG1183	phosphatidylcholine synthase activity
ASALC70_01372	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASALC70_01373	COG0583	DNA-binding transcription factor activity
ASALC70_01378	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_01381	COG0028	Belongs to the TPP enzyme family
ASALC70_01382	COG0028	Belongs to the TPP enzyme family
ASALC70_01391	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASALC70_01391	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_01403	COG4966	pilus assembly protein PilW
ASALC70_01405	COG4969	Belongs to the N-Me-Phe pilin family
ASALC70_01406	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ASALC70_01408	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASALC70_01409	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASALC70_01410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASALC70_01411	COG0196	riboflavin kinase activity
ASALC70_01412	COG0728	peptidoglycan biosynthetic process
ASALC70_01413	COG0268	Binds directly to 16S ribosomal RNA
ASALC70_01414	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASALC70_01415	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASALC70_01416	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASALC70_01417	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ASALC70_01418	COG0142	geranyltranstransferase activity
ASALC70_01427	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_01430	COG4999	Histidine kinase
ASALC70_01430	COG2205	protein histidine kinase activity
ASALC70_01430	COG3437	response regulator, receiver
ASALC70_01430	COG3850	Histidine kinase
ASALC70_01431	COG0784	Response regulator, receiver
ASALC70_01431	COG5002	protein histidine kinase activity
ASALC70_01431	COG2205	protein histidine kinase activity
ASALC70_01437	COG0778	Nitroreductase
ASALC70_01438	COG4221	oxidoreductase activity
ASALC70_01451	COG3031	protein transport across the cell outer membrane
ASALC70_01454	COG2814	Major facilitator Superfamily
ASALC70_01455	COG2814	Major facilitator Superfamily
ASALC70_01456	COG2197	response regulator
ASALC70_01461	COG0659	secondary active sulfate transmembrane transporter activity
ASALC70_01465	COG0203	ribosomal protein L17
ASALC70_01466	COG0202	RNA polymerase activity
ASALC70_01467	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASALC70_01468	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASALC70_01469	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASALC70_01470	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASALC70_01473	COG0200	Binds to the 23S rRNA
ASALC70_01474	COG1841	ribosomal large subunit assembly
ASALC70_01475	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ASALC70_01476	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASALC70_01477	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASALC70_01478	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASALC70_01479	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASALC70_01480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASALC70_01481	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASALC70_01482	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASALC70_01483	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASALC70_01484	COG0255	Belongs to the universal ribosomal protein uL29 family
ASALC70_01485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASALC70_01486	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASALC70_01487	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ASALC70_01488	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASALC70_01489	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASALC70_01490	COG0089	rRNA binding
ASALC70_01491	COG0088	Forms part of the polypeptide exit tunnel
ASALC70_01492	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASALC70_01493	COG0051	transcription antitermination factor activity, RNA binding
ASALC70_01494	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASALC70_01495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASALC70_01496	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASALC70_01497	COG0049	tRNA binding
ASALC70_01498	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASALC70_01499	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ASALC70_01500	COG0085	RNA polymerase activity
ASALC70_01501	COG0222	ribosome binding
ASALC70_01502	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ASALC70_01504	COG0081	regulation of translation
ASALC70_01505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASALC70_01509	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASALC70_01515	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASALC70_01516	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASALC70_01516	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASALC70_01518	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_01519	COG1022	Amp-dependent synthetase and ligase
ASALC70_01521	COG2433	Pfam Transposase IS66
ASALC70_01528	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASALC70_01529	COG0739	heme binding
ASALC70_01530	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASALC70_01531	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ASALC70_01533	COG0316	Belongs to the HesB IscA family
ASALC70_01538	COG1981	membrane
ASALC70_01539	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ASALC70_01539	COG0351	phosphomethylpyrimidine kinase
ASALC70_01539	COG0352	thiamine-phosphate diphosphorylase activity
ASALC70_01540	COG0351	phosphomethylpyrimidine kinase
ASALC70_01541	COG0352	thiamine-phosphate diphosphorylase activity
ASALC70_01542	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASALC70_01548	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASALC70_01549	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASALC70_01553	COG1489	DNA binding
ASALC70_01554	COG0436	Aminotransferase
ASALC70_01556	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASALC70_01557	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASALC70_01558	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASALC70_01560	COG3852	Histidine kinase
ASALC70_01564	COG1428	Deoxynucleoside kinase
ASALC70_01565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASALC70_01566	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASALC70_01567	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASALC70_01568	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_01569	COG2814	Major facilitator Superfamily
ASALC70_01570	COG1566	PFAM secretion protein HlyD family protein
ASALC70_01572	COG1185	polyribonucleotide nucleotidyltransferase activity
ASALC70_01574	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASALC70_01575	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASALC70_01576	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ASALC70_01577	COG0195	Participates in both transcription termination and antitermination
ASALC70_01578	COG0779	Required for maturation of 30S ribosomal subunits
ASALC70_01582	COG0149	triose-phosphate isomerase activity
ASALC70_01583	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASALC70_01584	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASALC70_01585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASALC70_01586	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ASALC70_01588	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASALC70_01589	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ASALC70_01590	COG0505	Belongs to the CarA family
ASALC70_01591	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ASALC70_01592	COG0484	heat shock protein binding
ASALC70_01593	COG0484	heat shock protein binding
ASALC70_01594	COG0443	Heat shock 70 kDa protein
ASALC70_01595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASALC70_01596	COG1420	regulation of RNA biosynthetic process
ASALC70_01597	COG0497	DNA recombination
ASALC70_01599	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASALC70_01600	COG0733	neurotransmitter:sodium symporter activity
ASALC70_01601	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASALC70_01609	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_01611	COG0154	amidase activity
ASALC70_01613	COG1802	Transcriptional regulator
ASALC70_01617	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_01624	COG2807	transmembrane transport
ASALC70_01628	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_01629	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_01630	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASALC70_01631	COG0402	S-adenosylhomocysteine deaminase activity
ASALC70_01632	COG1228	amidohydrolase
ASALC70_01643	COG0596	Alpha beta hydrolase
ASALC70_01643	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_01643	COG2226	methyltransferase
ASALC70_01645	COG1116	anion transmembrane transporter activity
ASALC70_01646	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_01650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASALC70_01652	COG0519	Catalyzes the synthesis of GMP from XMP
ASALC70_01652	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASALC70_01653	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASALC70_01654	COG1522	sequence-specific DNA binding
ASALC70_01663	COG3540	Alkaline phosphatase
ASALC70_01664	COG3540	Alkaline phosphatase
ASALC70_01665	COG1881	PFAM PEBP family protein
ASALC70_01668	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASALC70_01669	COG2226	methyltransferase
ASALC70_01670	COG0596	Alpha beta hydrolase
ASALC70_01671	COG0156	8-amino-7-oxononanoate synthase activity
ASALC70_01672	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASALC70_01675	COG2045	Belongs to the ComB family
ASALC70_01677	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASALC70_01682	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASALC70_01683	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASALC70_01684	COG0493	'glutamate synthase
ASALC70_01685	COG0493	'glutamate synthase
ASALC70_01686	COG0070	glutamate synthase
ASALC70_01686	COG0069	glutamate synthase activity
ASALC70_01686	COG0067	glutamate synthase
ASALC70_01687	COG0067	glutamate synthase
ASALC70_01687	COG0069	glutamate synthase activity
ASALC70_01687	COG0070	glutamate synthase
ASALC70_01688	COG0067	glutamate synthase
ASALC70_01688	COG0069	glutamate synthase activity
ASALC70_01688	COG0070	glutamate synthase
ASALC70_01691	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ASALC70_01692	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASALC70_01703	COG0281	malic enzyme
ASALC70_01704	COG0254	rRNA binding
ASALC70_01705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ASALC70_01706	COG0477	Major facilitator Superfamily
ASALC70_01709	COG1566	PFAM secretion protein HlyD family protein
ASALC70_01710	COG0018	arginyl-trna synthetase
ASALC70_01713	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ASALC70_01714	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ASALC70_01716	COG2226	methyltransferase
ASALC70_01718	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_01719	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASALC70_01720	COG0140	phosphoribosyl-ATP diphosphatase activity
ASALC70_01721	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASALC70_01722	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASALC70_01725	COG1073	alpha beta
ASALC70_01729	COG1490	D-aminoacyl-tRNA deacylase activity
ASALC70_01735	COG3852	Histidine kinase
ASALC70_01738	COG0174	glutamine synthetase
ASALC70_01739	COG0425	Belongs to the sulfur carrier protein TusA family
ASALC70_01740	COG0482	sulfurtransferase activity
ASALC70_01741	COG3083	sulfuric ester hydrolase activity
ASALC70_01743	COG0189	ligase activity
ASALC70_01746	COG1217	gtp-binding protein TYPA
ASALC70_01747	COG1217	gtp-binding protein TYPA
ASALC70_01749	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASALC70_01750	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ASALC70_01752	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASALC70_01753	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASALC70_01754	COG4942	peptidase
ASALC70_01755	COG0793	Belongs to the peptidase S41A family
ASALC70_01756	COG0793	Belongs to the peptidase S41A family
ASALC70_01758	COG0385	Bile acid
ASALC70_01761	COG1671	Belongs to the UPF0178 family
ASALC70_01762	COG0107	imidazoleglycerol-phosphate synthase activity
ASALC70_01764	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASALC70_01765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASALC70_01766	COG0131	Imidazoleglycerol-phosphate dehydratase
ASALC70_01771	COG1194	a g-specific adenine glycosylase
ASALC70_01773	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASALC70_01795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_01797	COG1116	anion transmembrane transporter activity
ASALC70_01799	COG1309	transcriptional regulator
ASALC70_01800	COG0174	glutamine synthetase
ASALC70_01801	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_01804	COG0739	heme binding
ASALC70_01806	COG1335	isochorismatase
ASALC70_01807	COG3845	ABC transporter
ASALC70_01809	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASALC70_01811	COG1079	Belongs to the binding-protein-dependent transport system permease family
ASALC70_01812	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASALC70_01815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_01817	COG1116	anion transmembrane transporter activity
ASALC70_01821	COG0583	DNA-binding transcription factor activity
ASALC70_01824	COG0439	Biotin carboxylase
ASALC70_01825	COG0511	ligase activity, forming carbon-carbon bonds
ASALC70_01826	COG1802	Transcriptional regulator
ASALC70_01830	COG0411	ABC transporter
ASALC70_01835	COG1733	regulation of RNA biosynthetic process
ASALC70_01837	COG0024	Methionine aminopeptidase
ASALC70_01848	COG0656	L-ascorbic acid biosynthetic process
ASALC70_01850	COG2207	Transcriptional regulator
ASALC70_01851	COG4221	oxidoreductase activity
ASALC70_01857	COG0259	pyridoxamine-phosphate oxidase activity
ASALC70_01861	COG3239	Fatty acid desaturase
ASALC70_01867	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASALC70_01879	COG3012	SEC-C Motif Domain Protein
ASALC70_01881	COG3093	addiction module antidote protein HigA
ASALC70_01883	COG2375	cellular response to nickel ion
ASALC70_01887	COG0183	Belongs to the thiolase family
ASALC70_01891	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_01892	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_01893	COG2031	fatty acid transporter
ASALC70_01899	COG4977	sequence-specific DNA binding
ASALC70_01900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASALC70_01901	COG0473	3-isopropylmalate dehydrogenase activity
ASALC70_01906	COG0667	Aldo Keto reductase
ASALC70_01907	COG0583	DNA-binding transcription factor activity
ASALC70_01912	COG1960	acyl-CoA dehydrogenase activity
ASALC70_01913	COG2072	flavoprotein involved in K transport
ASALC70_01918	COG2801	Transposase and inactivated derivatives
ASALC70_01921	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_01924	COG0444	Belongs to the ABC transporter superfamily
ASALC70_01925	COG4608	Belongs to the ABC transporter superfamily
ASALC70_01928	COG0601	transmembrane transport
ASALC70_01929	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASALC70_01935	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASALC70_01936	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ASALC70_01938	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ASALC70_01942	COG4206	TonB-dependent receptor
ASALC70_01944	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASALC70_01945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASALC70_01946	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASALC70_01948	COG1492	cobalamin metabolic process
ASALC70_01954	COG0494	nUDIX hydrolase
ASALC70_01958	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_01959	COG1960	acyl-CoA dehydrogenase activity
ASALC70_01960	COG0583	DNA-binding transcription factor activity
ASALC70_01964	COG2217	Heavy metal translocating P-type atpase
ASALC70_01979	COG0730	response to heat
ASALC70_01991	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_01992	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_01994	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_01996	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASALC70_01998	COG0154	amidase activity
ASALC70_01999	COG0346	lactoylglutathione lyase activity
ASALC70_02007	COG2031	fatty acid transporter
ASALC70_02008	COG2031	fatty acid transporter
ASALC70_02010	COG0628	permease
ASALC70_02011	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASALC70_02014	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ASALC70_02021	COG1360	Flagellar Motor Protein
ASALC70_02025	COG0625	glutathione transferase activity
ASALC70_02026	COG2824	Alkylphosphonate utilization operon protein PhnA
ASALC70_02037	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ASALC70_02041	COG1944	ATP diphosphatase activity
ASALC70_02042	COG1944	ATP diphosphatase activity
ASALC70_02052	COG3712	iron ion homeostasis
ASALC70_02057	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASALC70_02062	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASALC70_02063	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASALC70_02064	COG0509	glycine decarboxylation via glycine cleavage system
ASALC70_02065	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASALC70_02069	COG2223	nitrite transmembrane transporter activity
ASALC70_02073	COG3383	formate dehydrogenase (NAD+) activity
ASALC70_02074	COG3383	formate dehydrogenase (NAD+) activity
ASALC70_02076	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_02077	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_02078	COG0006	proline dipeptidase activity
ASALC70_02079	COG0006	proline dipeptidase activity
ASALC70_02080	COG3079	Belongs to the UPF0149 family
ASALC70_02084	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASALC70_02086	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASALC70_02087	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ASALC70_02088	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ASALC70_02098	COG0583	DNA-binding transcription factor activity
ASALC70_02099	COG1228	amidohydrolase
ASALC70_02103	COG0126	phosphoglycerate kinase activity
ASALC70_02104	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASALC70_02105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ASALC70_02106	COG0640	Transcriptional regulator
ASALC70_02107	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASALC70_02108	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASALC70_02109	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ASALC70_02112	COG1307	EDD domain protein, DegV family
ASALC70_02117	COG0656	L-ascorbic acid biosynthetic process
ASALC70_02118	COG0656	L-ascorbic acid biosynthetic process
ASALC70_02119	COG0583	DNA-binding transcription factor activity
ASALC70_02120	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ASALC70_02123	COG0534	Mate efflux family protein
ASALC70_02128	COG0742	ribosomal rna small subunit methyltransferase
ASALC70_02131	COG0612	Peptidase, M16
ASALC70_02133	COG0552	protein localization to endoplasmic reticulum
ASALC70_02134	COG0552	protein localization to endoplasmic reticulum
ASALC70_02135	COG2884	Cell division ATP-binding protein ftsE
ASALC70_02136	COG2177	Part of the ABC transporter FtsEX involved in
ASALC70_02138	COG2363	Small membrane protein
ASALC70_02140	COG2022	thiamine diphosphate biosynthetic process
ASALC70_02141	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASALC70_02149	COG0693	protein deglycase activity
ASALC70_02150	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_02151	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASALC70_02151	COG2813	Specifically methylates the guanine in position
ASALC70_02152	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASALC70_02153	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ASALC70_02154	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_02155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_02158	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASALC70_02175	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ASALC70_02176	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASALC70_02177	COG2003	Belongs to the UPF0758 family
ASALC70_02178	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ASALC70_02179	COG0756	dUTP diphosphatase activity
ASALC70_02183	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASALC70_02184	COG1309	transcriptional regulator
ASALC70_02186	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ASALC70_02187	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASALC70_02188	COG1561	YicC-like family, N-terminal region
ASALC70_02189	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_02190	COG1725	Transcriptional regulator
ASALC70_02203	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_02204	COG3608	succinylglutamate desuccinylase aspartoacylase
ASALC70_02205	COG0194	GDP metabolic process
ASALC70_02206	COG1758	RNA polymerase activity
ASALC70_02207	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASALC70_02212	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASALC70_02213	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ASALC70_02214	COG0583	DNA-binding transcription factor activity
ASALC70_02215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASALC70_02216	COG5507	3-demethylubiquinone-9 3-methyltransferase
ASALC70_02222	COG0583	DNA-binding transcription factor activity
ASALC70_02230	COG0339	signal peptide processing
ASALC70_02231	COG0339	signal peptide processing
ASALC70_02232	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ASALC70_02234	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASALC70_02235	COG0408	coproporphyrinogen oxidase activity
ASALC70_02236	COG0009	L-threonylcarbamoyladenylate synthase
ASALC70_02237	COG0758	DNA mediated transformation
ASALC70_02238	COG0758	DNA mediated transformation
ASALC70_02240	COG0242	peptide deformylase activity
ASALC70_02241	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASALC70_02244	COG0569	domain protein
ASALC70_02245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_02246	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_02247	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_02248	COG3239	Fatty acid desaturase
ASALC70_02249	COG3239	Fatty acid desaturase
ASALC70_02250	COG2186	Transcriptional regulator
ASALC70_02254	COG3039	Transposase
ASALC70_02262	COG2132	Multicopper oxidase
ASALC70_02263	COG2132	Multicopper oxidase
ASALC70_02276	COG1960	acyl-CoA dehydrogenase activity
ASALC70_02282	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASALC70_02291	COG1764	response to oxidative stress
ASALC70_02293	COG0435	Glutathione S-transferase
ASALC70_02294	COG0435	Glutathione S-transferase
ASALC70_02295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ASALC70_02299	COG4771	TonB-dependent receptor
ASALC70_02300	COG1858	cytochrome C peroxidase
ASALC70_02301	COG0583	DNA-binding transcription factor activity
ASALC70_02305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASALC70_02308	COG0540	Belongs to the ATCase OTCase family
ASALC70_02311	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ASALC70_02312	COG1678	Uncharacterized ACR, COG1678
ASALC70_02314	COG0189	ligase activity
ASALC70_02318	COG0840	transmembrane signaling receptor activity
ASALC70_02324	COG0643	Histidine kinase
ASALC70_02324	COG2198	Histidine kinase
ASALC70_02325	COG2201	protein-glutamate methylesterase activity
ASALC70_02329	COG3038	cytochrome b561
ASALC70_02331	COG1047	Peptidyl-prolyl cis-trans
ASALC70_02333	COG0330	HflC and HflK could
ASALC70_02335	COG0154	amidase activity
ASALC70_02337	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ASALC70_02346	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASALC70_02347	COG0405	Gamma-glutamyltransferase
ASALC70_02348	COG0405	Gamma-glutamyltransferase
ASALC70_02350	COG4977	sequence-specific DNA binding
ASALC70_02358	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASALC70_02359	COG0277	FAD linked oxidase domain protein
ASALC70_02360	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASALC70_02361	COG0189	ligase activity
ASALC70_02361	COG4067	protein conserved in archaea
ASALC70_02364	COG0110	maltose O-acetyltransferase activity
ASALC70_02365	COG0519	Catalyzes the synthesis of GMP from XMP
ASALC70_02365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASALC70_02366	COG2818	Glycosylase
ASALC70_02367	COG0752	glycyl-tRNA synthetase alpha subunit
ASALC70_02368	COG0751	glycine-tRNA ligase activity
ASALC70_02376	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_02382	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASALC70_02383	COG0592	DNA-directed DNA polymerase activity
ASALC70_02384	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASALC70_02385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ASALC70_02386	COG0594	ribonuclease P activity
ASALC70_02387	COG0706	membrane insertase activity
ASALC70_02388	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ASALC70_02391	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_02392	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_02393	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_02395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_02397	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASALC70_02400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASALC70_02404	COG1960	acyl-CoA dehydrogenase activity
ASALC70_02405	COG0300	oxidoreductase activity
ASALC70_02406	COG3263	regulation of cellular component size
ASALC70_02408	COG0445	tRNA wobble uridine modification
ASALC70_02409	COG0357	Ribosomal RNA small subunit methyltransferase G
ASALC70_02410	COG1192	Involved in chromosome partitioning
ASALC70_02411	COG1475	DNA binding
ASALC70_02413	COG0356	it plays a direct role in the translocation of protons across the membrane
ASALC70_02415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ASALC70_02416	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASALC70_02417	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASALC70_02418	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASALC70_02419	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASALC70_02420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASALC70_02421	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASALC70_02422	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASALC70_02427	COG4221	oxidoreductase activity
ASALC70_02431	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASALC70_02431	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASALC70_02432	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_02433	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_02436	COG2853	Lipoprotein
ASALC70_02443	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_02446	COG1309	transcriptional regulator
ASALC70_02447	COG1960	acyl-CoA dehydrogenase activity
ASALC70_02450	COG0668	transmembrane transport
ASALC70_02454	COG0210	DNA helicase
ASALC70_02455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASALC70_02456	COG1607	acyl-coa hydrolase
ASALC70_02457	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_02460	COG0573	inorganic phosphate transmembrane transporter activity
ASALC70_02462	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASALC70_02463	COG0704	Plays a role in the regulation of phosphate uptake
ASALC70_02464	COG0640	Transcriptional regulator
ASALC70_02466	COG0798	PFAM Bile acid sodium symporter
ASALC70_02467	COG0431	NADPH-dependent FMN reductase
ASALC70_02470	COG4681	YaeQ
ASALC70_02471	COG2119	membrane
ASALC70_02472	COG2119	membrane
ASALC70_02474	COG2900	Belongs to the SlyX family
ASALC70_02477	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASALC70_02478	COG3161	chorismate lyase activity
ASALC70_02479	COG1773	rubredoxin
ASALC70_02480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_02481	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_02484	COG0534	Mate efflux family protein
ASALC70_02485	COG0534	Mate efflux family protein
ASALC70_02486	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASALC70_02487	COG1121	(ABC) transporter
ASALC70_02490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ASALC70_02494	COG0500	methyltransferase
ASALC70_02496	COG1643	Atp-dependent helicase
ASALC70_02499	COG0678	peroxiredoxin activity
ASALC70_02501	COG0668	transmembrane transport
ASALC70_02502	COG0028	Belongs to the TPP enzyme family
ASALC70_02503	COG0436	Aminotransferase
ASALC70_02507	COG0842	Transport permease protein
ASALC70_02508	COG1131	(ABC) transporter
ASALC70_02513	COG0154	amidase activity
ASALC70_02514	COG0154	amidase activity
ASALC70_02515	COG5285	phytanoyl-CoA dioxygenase
ASALC70_02517	COG1960	acyl-CoA dehydrogenase activity
ASALC70_02520	COG2610	gluconate transmembrane transporter activity
ASALC70_02521	COG2610	gluconate transmembrane transporter activity
ASALC70_02524	COG1160	GTP binding
ASALC70_02530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASALC70_02530	COG2111	Na H antiporter
ASALC70_02531	COG1006	Multisubunit Na H antiporter MnhC subunit
ASALC70_02532	COG0651	ATP synthesis coupled electron transport
ASALC70_02533	COG1863	multisubunit Na H antiporter MnhE subunit
ASALC70_02534	COG2212	antiporter activity
ASALC70_02536	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ASALC70_02557	COG4964	Belongs to the GSP D family
ASALC70_02567	COG0386	Belongs to the glutathione peroxidase family
ASALC70_02570	COG0640	Transcriptional regulator
ASALC70_02571	COG1272	protein, Hemolysin III
ASALC70_02572	COG0783	Belongs to the Dps family
ASALC70_02575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_02586	COG1024	Enoyl-CoA hydratase
ASALC70_02591	COG0385	Bile acid
ASALC70_02592	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASALC70_02593	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_02599	COG1566	PFAM secretion protein HlyD family protein
ASALC70_02608	COG1515	deoxyribonuclease V activity
ASALC70_02613	COG0469	pyruvate kinase activity
ASALC70_02615	COG0745	RESPONSE REGULATOR receiver
ASALC70_02618	COG2205	protein histidine kinase activity
ASALC70_02619	COG3245	cytochrome
ASALC70_02621	COG0210	DNA helicase
ASALC70_02627	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_02628	COG0697	spore germination
ASALC70_02629	COG0606	chelatase, subunit chli
ASALC70_02630	COG2960	long-chain fatty acid transporting porin activity
ASALC70_02631	COG0347	Belongs to the P(II) protein family
ASALC70_02632	COG0004	ammonium transporteR
ASALC70_02634	COG2995	paraquat-inducible protein a
ASALC70_02635	COG3008	intermembrane lipid transfer
ASALC70_02644	COG1166	arginine decarboxylase activity
ASALC70_02646	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASALC70_02647	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASALC70_02649	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASALC70_02650	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_02652	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ASALC70_02661	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASALC70_02669	COG1047	Peptidyl-prolyl cis-trans
ASALC70_02670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ASALC70_02671	COG0288	reversible hydration of carbon dioxide
ASALC70_02673	COG2132	Multicopper oxidase
ASALC70_02676	COG3852	Histidine kinase
ASALC70_02677	COG2204	response regulator
ASALC70_02684	COG0347	Belongs to the P(II) protein family
ASALC70_02685	COG0463	Glycosyl transferase, family 2
ASALC70_02690	COG4372	Transposase
ASALC70_02695	COG0789	Transcriptional regulator
ASALC70_02697	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ASALC70_02698	COG0789	Transcriptional regulator
ASALC70_02707	COG3530	Putative quorum-sensing-regulated virulence factor
ASALC70_02708	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_02709	COG0577	efflux transmembrane transporter activity
ASALC70_02709	COG1136	(ABC) transporter
ASALC70_02711	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASALC70_02716	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASALC70_02722	COG0247	lactate metabolic process
ASALC70_02723	COG0277	FAD linked oxidase domain protein
ASALC70_02724	COG0277	FAD linked oxidase domain protein
ASALC70_02725	COG0277	FAD linked oxidase domain protein
ASALC70_02726	COG0745	RESPONSE REGULATOR receiver
ASALC70_02727	COG0745	RESPONSE REGULATOR receiver
ASALC70_02728	COG2205	protein histidine kinase activity
ASALC70_02734	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASALC70_02735	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASALC70_02738	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASALC70_02741	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASALC70_02744	COG0248	Ppx GppA phosphatase
ASALC70_02747	COG4774	siderophore transport
ASALC70_02749	COG0531	amino acid
ASALC70_02750	COG1982	Orn Lys Arg decarboxylase major
ASALC70_02751	COG1982	Orn Lys Arg decarboxylase major
ASALC70_02755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASALC70_02757	COG0488	(ABC) transporter
ASALC70_02763	COG1346	cytolysis
ASALC70_02765	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ASALC70_02767	COG2918	glutathione biosynthetic process
ASALC70_02768	COG2183	response to ionizing radiation
ASALC70_02773	COG2814	Major facilitator Superfamily
ASALC70_02775	COG3712	iron ion homeostasis
ASALC70_02776	COG4774	siderophore transport
ASALC70_02776	COG1629	transport
ASALC70_02779	COG0129	dihydroxy-acid dehydratase activity
ASALC70_02780	COG0165	Argininosuccinate lyase
ASALC70_02781	COG3275	phosphorelay sensor kinase activity
ASALC70_02783	COG0181	hydroxymethylbilane synthase activity
ASALC70_02789	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ASALC70_02789	COG3008	intermembrane lipid transfer
ASALC70_02790	COG2995	paraquat-inducible protein a
ASALC70_02792	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASALC70_02792	COG0543	2 iron, 2 sulfur cluster binding
ASALC70_02796	COG0129	dihydroxy-acid dehydratase activity
ASALC70_02797	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASALC70_02797	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASALC70_02798	COG0306	phosphate transporter
ASALC70_02799	COG0306	phosphate transporter
ASALC70_02800	COG1392	Phosphate transport regulator
ASALC70_02801	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ASALC70_02802	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASALC70_02804	COG0859	PFAM glycosyl transferase family 9
ASALC70_02806	COG0859	PFAM glycosyl transferase family 9
ASALC70_02807	COG0438	transferase activity, transferring glycosyl groups
ASALC70_02809	COG1215	transferase activity, transferring glycosyl groups
ASALC70_02811	COG3562	capsule polysaccharide
ASALC70_02815	COG1560	Kdo2-lipid A biosynthetic process
ASALC70_02818	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ASALC70_02818	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ASALC70_02821	COG1051	belongs to the nudix hydrolase family
ASALC70_02826	COG0730	response to heat
ASALC70_02827	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASALC70_02828	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASALC70_02837	COG3098	single-species biofilm formation
ASALC70_02838	COG0546	phosphoglycolate phosphatase activity
ASALC70_02839	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ASALC70_02841	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASALC70_02842	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ASALC70_02843	COG1215	transferase activity, transferring glycosyl groups
ASALC70_02847	COG1595	DNA-templated transcription, initiation
ASALC70_02848	COG3712	iron ion homeostasis
ASALC70_02852	COG2608	mercury ion transmembrane transporter activity
ASALC70_02865	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASALC70_02867	COG2133	pyrroloquinoline quinone binding
ASALC70_02868	COG2133	pyrroloquinoline quinone binding
ASALC70_02870	COG0625	glutathione transferase activity
ASALC70_02872	COG1295	ribonuclease BN
ASALC70_02873	COG1252	NADH dehydrogenase
ASALC70_02874	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASALC70_02875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ASALC70_02876	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ASALC70_02877	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ASALC70_02878	COG1011	Hydrolase
ASALC70_02879	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASALC70_02881	COG0667	Aldo Keto reductase
ASALC70_02883	COG1519	Transferase
ASALC70_02884	COG1519	Transferase
ASALC70_02885	COG1519	Transferase
ASALC70_02886	COG1538	Outer membrane efflux protein
ASALC70_02887	COG1538	Outer membrane efflux protein
ASALC70_02888	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASALC70_02889	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASALC70_02890	COG0494	nUDIX hydrolase
ASALC70_02891	COG3151	Protein conserved in bacteria
ASALC70_02892	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASALC70_02893	COG1283	sodium-dependent phosphate transmembrane transporter activity
ASALC70_02894	COG3150	esterase
ASALC70_02899	COG0204	Acyl-transferase
ASALC70_02901	COG3122	Protein conserved in bacteria
ASALC70_02903	COG2207	Transcriptional regulator
ASALC70_02904	COG2366	antibiotic biosynthetic process
ASALC70_02905	COG0183	Belongs to the thiolase family
ASALC70_02906	COG2267	carboxylic ester hydrolase activity
ASALC70_02907	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ASALC70_02908	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASALC70_02909	COG1509	lysine 2,3-aminomutase activity
ASALC70_02912	COG0560	Phosphoserine phosphatase
ASALC70_02912	COG3830	Belongs to the UPF0237 family
ASALC70_02914	COG1024	Enoyl-CoA hydratase
ASALC70_02915	COG0688	phosphatidylethanolamine metabolic process
ASALC70_02917	COG1162	GTPase activity
ASALC70_02918	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASALC70_02921	COG3909	cytochrome
ASALC70_02924	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ASALC70_02924	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ASALC70_02925	COG0802	atpase or kinase
ASALC70_02926	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASALC70_02927	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASALC70_02928	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ASALC70_02929	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASALC70_02930	COG1923	regulation of RNA biosynthetic process
ASALC70_02931	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASALC70_02932	COG0330	HflC and HflK could
ASALC70_02933	COG0330	HflC and HflK could
ASALC70_02938	COG0745	RESPONSE REGULATOR receiver
ASALC70_02941	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ASALC70_02942	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASALC70_02950	COG0557	exoribonuclease II activity
ASALC70_02951	COG0557	exoribonuclease II activity
ASALC70_02953	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASALC70_02954	COG0360	Binds together with S18 to 16S ribosomal RNA
ASALC70_02956	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASALC70_02957	COG0359	binds to the 23S rRNA
ASALC70_02960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASALC70_02961	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASALC70_02962	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASALC70_02963	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASALC70_02964	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASALC70_02965	COG0569	domain protein
ASALC70_02966	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_02967	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASALC70_02972	COG2226	methyltransferase
ASALC70_02973	COG2203	Gaf domain
ASALC70_02973	COG3706	GGDEF domain
ASALC70_02973	COG4251	negative regulation of phosphorylation
ASALC70_02973	COG5001	Diguanylate cyclase
ASALC70_02975	COG0243	molybdopterin cofactor binding
ASALC70_02976	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASALC70_02980	COG1595	DNA-templated transcription, initiation
ASALC70_02981	COG0488	(ABC) transporter
ASALC70_02982	COG0840	transmembrane signaling receptor activity
ASALC70_02983	COG0840	transmembrane signaling receptor activity
ASALC70_02984	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASALC70_02986	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ASALC70_02987	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASALC70_02987	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASALC70_02991	COG3396	Phenylacetate-CoA oxygenase
ASALC70_02992	COG3460	Phenylacetate-CoA oxygenase
ASALC70_02993	COG3396	Phenylacetate-CoA oxygenase
ASALC70_02994	COG2151	metal-sulfur cluster biosynthetic enzyme
ASALC70_02995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASALC70_02997	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_02997	COG2030	dehydratase
ASALC70_02998	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_02998	COG2030	dehydratase
ASALC70_03013	COG0456	acetyltransferase
ASALC70_03014	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ASALC70_03015	COG0842	Transport permease protein
ASALC70_03016	COG1129	ABC transporter
ASALC70_03016	COG0842	Transport permease protein
ASALC70_03017	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_03018	COG1053	succinate dehydrogenase
ASALC70_03020	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03021	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03022	COG2871	sodium ion transport
ASALC70_03023	COG2871	sodium ion transport
ASALC70_03024	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_03028	COG1805	sodium ion transport
ASALC70_03030	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_03031	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_03032	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ASALC70_03033	COG0826	peptidase U32
ASALC70_03034	COG0826	peptidase U32
ASALC70_03039	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_03040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ASALC70_03044	COG0737	Belongs to the 5'-nucleotidase family
ASALC70_03049	COG0439	Biotin carboxylase
ASALC70_03059	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASALC70_03061	COG3327	negative regulation of DNA-templated transcription, initiation
ASALC70_03063	COG1024	Enoyl-CoA hydratase
ASALC70_03065	COG0183	Belongs to the thiolase family
ASALC70_03068	COG1742	UPF0060 membrane protein
ASALC70_03070	COG0583	DNA-binding transcription factor activity
ASALC70_03072	COG2226	methyltransferase
ASALC70_03075	COG0778	Nitroreductase
ASALC70_03077	COG1846	Transcriptional regulator
ASALC70_03080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_03081	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASALC70_03084	COG1335	isochorismatase
ASALC70_03086	COG3473	Maleate cis-trans isomerase
ASALC70_03087	COG0596	Alpha beta hydrolase
ASALC70_03098	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASALC70_03099	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ASALC70_03101	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ASALC70_03102	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASALC70_03103	COG0142	geranyltranstransferase activity
ASALC70_03108	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_03112	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASALC70_03114	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_03116	COG2205	protein histidine kinase activity
ASALC70_03118	COG0662	Cupin 2, conserved barrel domain protein
ASALC70_03119	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASALC70_03122	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ASALC70_03123	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_03124	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASALC70_03126	COG1469	GTP cyclohydrolase I activity
ASALC70_03131	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASALC70_03132	COG0215	cysteine-tRNA ligase activity
ASALC70_03133	COG0215	cysteine-tRNA ligase activity
ASALC70_03134	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASALC70_03137	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ASALC70_03138	COG2814	Major facilitator Superfamily
ASALC70_03140	COG2203	Gaf domain
ASALC70_03140	COG3706	GGDEF domain
ASALC70_03140	COG4251	negative regulation of phosphorylation
ASALC70_03140	COG5001	Diguanylate cyclase
ASALC70_03144	COG0537	adenosine 5'-monophosphoramidase activity
ASALC70_03149	COG2267	carboxylic ester hydrolase activity
ASALC70_03157	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03159	COG2835	tetraacyldisaccharide 4'-kinase activity
ASALC70_03160	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03162	COG2832	Protein of unknown function (DUF454)
ASALC70_03163	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03166	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03167	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASALC70_03172	COG1959	2 iron, 2 sulfur cluster binding
ASALC70_03174	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ASALC70_03183	COG1959	2 iron, 2 sulfur cluster binding
ASALC70_03184	COG3189	MarR family transcriptional regulator
ASALC70_03186	COG2070	2-Nitropropane dioxygenase
ASALC70_03191	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASALC70_03192	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASALC70_03194	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASALC70_03196	COG0583	DNA-binding transcription factor activity
ASALC70_03201	COG5642	Protein of unknown function (DUF2384)
ASALC70_03202	COG5654	RES domain protein
ASALC70_03206	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ASALC70_03211	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ASALC70_03212	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASALC70_03213	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ASALC70_03214	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASALC70_03215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ASALC70_03217	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03218	COG0617	tRNA 3'-terminal CCA addition
ASALC70_03222	COG3842	ATPase activity
ASALC70_03223	COG4149	molybdate abc transporter
ASALC70_03224	COG1840	ABC-type Fe3 transport system, periplasmic component
ASALC70_03226	COG2719	SpoVR family
ASALC70_03227	COG2718	Belongs to the UPF0229 family
ASALC70_03228	COG2766	serine protein kinase
ASALC70_03229	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ASALC70_03230	COG2967	ApaG domain
ASALC70_03231	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASALC70_03232	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ASALC70_03233	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASALC70_03234	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ASALC70_03235	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASALC70_03236	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ASALC70_03240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ASALC70_03242	COG0791	NLP P60 protein
ASALC70_03244	COG0477	Major facilitator Superfamily
ASALC70_03246	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASALC70_03247	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASALC70_03248	COG1845	cytochrome c oxidase, subunit III
ASALC70_03249	COG1845	cytochrome c oxidase, subunit III
ASALC70_03250	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ASALC70_03255	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ASALC70_03257	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASALC70_03258	COG0512	Glutamine amidotransferase of anthranilate synthase
ASALC70_03259	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASALC70_03260	COG0134	indole-3-glycerol-phosphate synthase activity
ASALC70_03264	COG1765	OsmC-like protein
ASALC70_03265	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ASALC70_03266	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ASALC70_03269	COG2205	protein histidine kinase activity
ASALC70_03269	COG3437	response regulator, receiver
ASALC70_03269	COG3850	Histidine kinase
ASALC70_03269	COG4999	Histidine kinase
ASALC70_03271	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_03273	COG0151	Belongs to the GarS family
ASALC70_03274	COG0138	bifunctional purine biosynthesis protein purh
ASALC70_03281	COG3547	Transposase (IS116 IS110 IS902 family)
ASALC70_03283	COG3547	Transposase (IS116 IS110 IS902 family)
ASALC70_03285	COG0511	ligase activity, forming carbon-carbon bonds
ASALC70_03286	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ASALC70_03290	COG0642	Histidine kinase
ASALC70_03292	COG2226	methyltransferase
ASALC70_03296	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03298	COG1022	Amp-dependent synthetase and ligase
ASALC70_03303	COG3047	cAMP biosynthetic process
ASALC70_03305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ASALC70_03315	COG0205	6-phosphofructokinase activity
ASALC70_03316	COG0205	6-phosphofructokinase activity
ASALC70_03322	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASALC70_03323	COG0163	prenyltransferase activity
ASALC70_03327	COG0848	biopolymer transport protein
ASALC70_03328	COG0811	peptide transport
ASALC70_03329	COG3015	lipoprotein NlpE involved in copper resistance
ASALC70_03332	COG1595	DNA-templated transcription, initiation
ASALC70_03333	COG3712	iron ion homeostasis
ASALC70_03334	COG4716	Myosin-crossreactive antigen
ASALC70_03350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASALC70_03351	COG0321	lipoyl(octanoyl) transferase activity
ASALC70_03355	COG1686	Belongs to the peptidase S11 family
ASALC70_03357	COG2951	lytic endotransglycosylase activity
ASALC70_03358	COG0772	Belongs to the SEDS family
ASALC70_03359	COG0768	penicillin binding
ASALC70_03360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ASALC70_03363	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASALC70_03367	COG0495	leucyl-tRNA aminoacylation
ASALC70_03370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASALC70_03370	COG3453	Protein conserved in bacteria
ASALC70_03372	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ASALC70_03373	COG4535	Mg2 and Co2 transporter CorC
ASALC70_03374	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASALC70_03375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASALC70_03376	COG1702	phosphate starvation-inducible protein PhoH
ASALC70_03377	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASALC70_03378	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ASALC70_03379	COG4208	sulfate ABC transporter
ASALC70_03381	COG1595	DNA-templated transcription, initiation
ASALC70_03385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ASALC70_03386	COG4150	thiosulfate binding
ASALC70_03388	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASALC70_03389	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASALC70_03390	COG1999	signal sequence binding
ASALC70_03396	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASALC70_03398	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ASALC70_03406	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASALC70_03407	COG1278	Cold shock
ASALC70_03411	COG0501	Belongs to the peptidase M48B family
ASALC70_03412	COG1704	LemA family
ASALC70_03413	COG0109	protoheme IX farnesyltransferase activity
ASALC70_03414	COG1612	heme a metabolic process
ASALC70_03419	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ASALC70_03420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASALC70_03421	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASALC70_03426	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASALC70_03431	COG3813	Protein conserved in bacteria
ASALC70_03432	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ASALC70_03435	COG4175	Glycine betaine
ASALC70_03437	COG4176	ABC-type proline glycine betaine transport system permease component
ASALC70_03439	COG2113	Glycine betaine
ASALC70_03444	COG3842	ATPase activity
ASALC70_03452	COG2827	Endonuclease containing a URI domain
ASALC70_03454	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASALC70_03456	COG2863	cytochrome
ASALC70_03458	COG3258	Cytochrome c
ASALC70_03461	COG1104	cysteine desulfurase activity
ASALC70_03463	COG2166	iron-sulfur cluster assembly
ASALC70_03464	COG2151	metal-sulfur cluster biosynthetic enzyme
ASALC70_03465	COG0316	Belongs to the HesB IscA family
ASALC70_03466	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ASALC70_03467	COG0719	Fe-S assembly protein
ASALC70_03468	COG0396	ATPase activity
ASALC70_03469	COG0719	Fe-S assembly protein
ASALC70_03470	COG0105	UTP biosynthetic process
ASALC70_03471	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASALC70_03473	COG1426	Protein conserved in bacteria
ASALC70_03475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASALC70_03476	COG0124	histidyl-tRNA synthetase
ASALC70_03478	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ASALC70_03479	COG1160	GTP binding
ASALC70_03482	COG5002	protein histidine kinase activity
ASALC70_03482	COG2205	protein histidine kinase activity
ASALC70_03482	COG0784	Response regulator, receiver
ASALC70_03483	COG1570	exodeoxyribonuclease VII activity
ASALC70_03485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASALC70_03485	COG0519	Catalyzes the synthesis of GMP from XMP
ASALC70_03486	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASALC70_03486	COG0519	Catalyzes the synthesis of GMP from XMP
ASALC70_03498	COG0653	protein targeting
ASALC70_03500	COG3609	addiction module antidote protein, CC2985 family
ASALC70_03512	COG1304	FMN binding
ASALC70_03517	COG2207	Transcriptional regulator
ASALC70_03517	COG0662	Cupin 2, conserved barrel domain protein
ASALC70_03522	COG2358	TRAP transporter, solute receptor (TAXI family
ASALC70_03525	COG0583	DNA-binding transcription factor activity
ASALC70_03526	COG0300	oxidoreductase activity
ASALC70_03527	COG2910	NAD(P)H-binding
ASALC70_03528	COG1733	regulation of RNA biosynthetic process
ASALC70_03529	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASALC70_03536	COG1309	transcriptional regulator
ASALC70_03543	COG0789	Transcriptional regulator
ASALC70_03544	COG0583	DNA-binding transcription factor activity
ASALC70_03545	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03550	COG2080	2 iron, 2 sulfur cluster binding
ASALC70_03551	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ASALC70_03552	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_03553	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASALC70_03557	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ASALC70_03558	COG2944	sequence-specific DNA binding
ASALC70_03559	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03566	COG3541	Predicted nucleotidyltransferase
ASALC70_03571	COG3938	Belongs to the proline racemase family
ASALC70_03580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASALC70_03581	COG1116	anion transmembrane transporter activity
ASALC70_03583	COG0657	acetylesterase activity
ASALC70_03593	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASALC70_03594	COG1414	Transcriptional regulator
ASALC70_03598	COG3971	2-oxopent-4-enoate hydratase activity
ASALC70_03604	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_03605	COG3647	Membrane
ASALC70_03608	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ASALC70_03608	COG1199	ATP-dependent helicase activity
ASALC70_03609	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ASALC70_03610	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_03625	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASALC70_03627	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASALC70_03628	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASALC70_03631	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ASALC70_03631	COG3323	Protein of unknown function (DUF1653)
ASALC70_03637	COG1752	Esterase of the alpha-beta hydrolase superfamily
ASALC70_03638	COG4536	flavin adenine dinucleotide binding
ASALC70_03645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ASALC70_03646	COG0228	four-way junction DNA binding
ASALC70_03647	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASALC70_03648	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASALC70_03649	COG0336	Belongs to the RNA methyltransferase TrmD family
ASALC70_03650	COG0335	large ribosomal subunit rRNA binding
ASALC70_03653	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASALC70_03654	COG0436	Aminotransferase
ASALC70_03656	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASALC70_03658	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASALC70_03660	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ASALC70_03663	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASALC70_03664	COG2264	protein methyltransferase activity
ASALC70_03665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASALC70_03666	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_03668	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASALC70_03674	COG2373	Large extracellular alpha-helical protein
ASALC70_03675	COG4953	penicillin-binding protein 1C
ASALC70_03677	COG0702	epimerase
ASALC70_03681	COG3547	Transposase (IS116 IS110 IS902 family)
ASALC70_03687	COG0488	(ABC) transporter
ASALC70_03688	COG0488	(ABC) transporter
ASALC70_03693	COG1196	nuclear chromosome segregation
ASALC70_03693	COG3264	Mechanosensitive ion channel
ASALC70_03696	COG0709	Synthesizes selenophosphate from selenide and ATP
ASALC70_03697	COG3639	organic phosphonate transmembrane transporter activity
ASALC70_03699	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ASALC70_03699	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ASALC70_03700	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ASALC70_03701	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ASALC70_03702	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ASALC70_03703	COG2030	dehydratase
ASALC70_03704	COG1309	transcriptional regulator
ASALC70_03709	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03710	COG0183	Belongs to the thiolase family
ASALC70_03711	COG0183	Belongs to the thiolase family
ASALC70_03712	COG1946	Acyl-CoA thioesterase
ASALC70_03720	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASALC70_03720	COG1902	pentaerythritol trinitrate reductase activity
ASALC70_03721	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03722	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03732	COG0642	Histidine kinase
ASALC70_03735	COG1115	amino acid carrier protein
ASALC70_03742	COG0071	Belongs to the small heat shock protein (HSP20) family
ASALC70_03743	COG3360	Dodecin
ASALC70_03745	COG2353	YceI-like domain
ASALC70_03753	COG4771	TonB-dependent receptor
ASALC70_03756	COG0175	sulfate reduction
ASALC70_03759	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_03764	COG0583	DNA-binding transcription factor activity
ASALC70_03766	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASALC70_03775	COG0488	(ABC) transporter
ASALC70_03779	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ASALC70_03781	COG2807	transmembrane transport
ASALC70_03784	COG1136	(ABC) transporter
ASALC70_03784	COG0577	efflux transmembrane transporter activity
ASALC70_03791	COG2856	Zn peptidase
ASALC70_03793	COG0183	Belongs to the thiolase family
ASALC70_03794	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_03794	COG1024	Enoyl-CoA hydratase
ASALC70_03795	COG1024	Enoyl-CoA hydratase
ASALC70_03795	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_03796	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ASALC70_03797	COG0280	phosphate acetyltransferase
ASALC70_03797	COG0281	malic enzyme
ASALC70_03800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASALC70_03802	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASALC70_03803	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ASALC70_03804	COG1024	Enoyl-CoA hydratase
ASALC70_03804	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_03809	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ASALC70_03816	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASALC70_03817	COG0481	GTPase activity
ASALC70_03818	COG0481	GTPase activity
ASALC70_03822	COG0571	ribonuclease III activity
ASALC70_03823	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ASALC70_03824	COG1381	Involved in DNA repair and RecF pathway recombination
ASALC70_03825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ASALC70_03826	COG0784	Response regulator, receiver
ASALC70_03826	COG2205	protein histidine kinase activity
ASALC70_03826	COG5002	protein histidine kinase activity
ASALC70_03829	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASALC70_03830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASALC70_03831	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASALC70_03832	COG3956	TIGRFAM MazG family protein
ASALC70_03833	COG3956	TIGRFAM MazG family protein
ASALC70_03837	COG0789	Transcriptional regulator
ASALC70_03838	COG3328	transposase activity
ASALC70_03843	COG3344	reverse transcriptase
ASALC70_03847	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ASALC70_03849	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASALC70_03852	COG0563	adenylate kinase activity
ASALC70_03853	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASALC70_03858	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASALC70_03858	COG1116	anion transmembrane transporter activity
ASALC70_03860	COG1999	signal sequence binding
ASALC70_03861	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ASALC70_03862	COG0583	DNA-binding transcription factor activity
ASALC70_03866	COG4133	protoheme IX ABC transporter activity
ASALC70_03867	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASALC70_03872	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ASALC70_03875	COG0189	ligase activity
ASALC70_03883	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ASALC70_03890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASALC70_03892	COG1131	(ABC) transporter
ASALC70_03893	COG0842	Transport permease protein
ASALC70_03894	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASALC70_03894	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ASALC70_03896	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASALC70_03898	COG0778	Nitroreductase
ASALC70_03908	COG0530	calcium, potassium:sodium antiporter activity
ASALC70_03910	COG2267	carboxylic ester hydrolase activity
ASALC70_03911	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_03914	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASALC70_03918	COG0683	leucine binding
ASALC70_03919	COG0531	amino acid
ASALC70_03920	COG1982	Orn Lys Arg decarboxylase major
ASALC70_03921	COG1982	Orn Lys Arg decarboxylase major
ASALC70_03922	COG0183	Belongs to the thiolase family
ASALC70_03923	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03925	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03926	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03927	COG1309	transcriptional regulator
ASALC70_03928	COG1024	Enoyl-CoA hydratase
ASALC70_03932	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03933	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03938	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03944	COG2205	protein histidine kinase activity
ASALC70_03944	COG0784	Response regulator, receiver
ASALC70_03956	COG4772	TonB-dependent receptor
ASALC70_03959	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_03962	COG3284	Transcriptional regulator
ASALC70_03963	COG3284	Transcriptional regulator
ASALC70_03965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_03966	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_03967	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASALC70_03968	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ASALC70_03969	COG1309	transcriptional regulator
ASALC70_03970	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03971	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_03974	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_03975	COG0559	Belongs to the binding-protein-dependent transport system permease family
ASALC70_03980	COG1024	Enoyl-CoA hydratase
ASALC70_03980	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASALC70_03982	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03983	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03984	COG2130	NADP-dependent
ASALC70_03985	COG2814	Major facilitator Superfamily
ASALC70_03986	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASALC70_03987	COG4774	siderophore transport
ASALC70_03991	COG0235	Class ii aldolase
ASALC70_03994	COG1960	acyl-CoA dehydrogenase activity
ASALC70_03995	COG0183	Belongs to the thiolase family
ASALC70_03996	COG0183	Belongs to the thiolase family
ASALC70_03997	COG1846	Transcriptional regulator
ASALC70_03998	COG1764	response to oxidative stress
ASALC70_04003	COG0513	Belongs to the DEAD box helicase family
ASALC70_04007	COG3115	cell septum assembly
ASALC70_04008	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASALC70_04009	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASALC70_04013	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ASALC70_04015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASALC70_04015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ASALC70_04020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASALC70_04021	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASALC70_04029	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_04031	COG1024	Enoyl-CoA hydratase
ASALC70_04032	COG1960	acyl-CoA dehydrogenase activity
ASALC70_04033	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASALC70_04034	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_04037	COG1309	transcriptional regulator
ASALC70_04043	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ASALC70_04044	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASALC70_04045	COG0308	aminopeptidase N
ASALC70_04047	COG3130	regulation of translation
ASALC70_04048	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASALC70_04048	COG0116	Belongs to the methyltransferase superfamily
ASALC70_04049	COG0116	Belongs to the methyltransferase superfamily
ASALC70_04049	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASALC70_04052	COG0471	metal ion transport
ASALC70_04052	COG3273	potassium ion transport
ASALC70_04054	COG0529	Catalyzes the synthesis of activated sulfate
ASALC70_04072	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASALC70_04074	COG0489	protein tyrosine kinase activity
ASALC70_04074	COG3206	protein involved in exopolysaccharide biosynthesis
ASALC70_04077	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ASALC70_04078	COG2433	Pfam Transposase IS66
ASALC70_04080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ASALC70_04087	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASALC70_04088	COG0110	maltose O-acetyltransferase activity
ASALC70_04091	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ASALC70_04096	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ASALC70_04098	COG3307	-O-antigen
ASALC70_04103	COG0489	protein tyrosine kinase activity
ASALC70_04108	COG0457	Tetratricopeptide repeat
ASALC70_04110	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ASALC70_04111	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASALC70_04112	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASALC70_04113	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASALC70_04115	COG0166	Belongs to the GPI family
ASALC70_04118	COG1960	acyl-CoA dehydrogenase activity
ASALC70_04121	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ASALC70_04123	COG0588	phosphoglycerate mutase activity
ASALC70_04125	COG3100	YcgL domain-containing protein
ASALC70_04126	COG2983	Belongs to the UPF0260 family
ASALC70_04128	COG0537	adenosine 5'-monophosphoramidase activity
ASALC70_04136	COG0318	PFAM AMP-dependent synthetase and ligase
ASALC70_04145	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_04146	COG0546	phosphoglycolate phosphatase activity
ASALC70_04147	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASALC70_04148	COG0402	S-adenosylhomocysteine deaminase activity
ASALC70_04150	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASALC70_04151	COG0077	Prephenate dehydratase
ASALC70_04151	COG1605	Chorismate mutase
ASALC70_04154	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASALC70_04155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASALC70_04157	COG0776	regulation of translation
ASALC70_04159	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ASALC70_04160	COG0284	orotidine-5'-phosphate decarboxylase activity
ASALC70_04163	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ASALC70_04166	COG4660	Part of a membrane complex involved in electron transport
ASALC70_04167	COG4659	FMN binding
ASALC70_04168	COG4658	electron transport chain
ASALC70_04169	COG4656	Part of a membrane complex involved in electron transport
ASALC70_04170	COG2878	Part of a membrane complex involved in electron transport
ASALC70_04171	COG4657	Part of a membrane complex involved in electron transport
ASALC70_04172	COG4657	Part of a membrane complex involved in electron transport
ASALC70_04175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASALC70_04175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASALC70_04176	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASALC70_04176	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASALC70_04179	COG0784	Response regulator, receiver
ASALC70_04179	COG2205	protein histidine kinase activity
ASALC70_04179	COG5002	protein histidine kinase activity
ASALC70_04180	COG3540	Alkaline phosphatase
ASALC70_04188	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ASALC70_04190	COG0501	Belongs to the peptidase M48B family
ASALC70_04191	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ASALC70_04193	COG0436	Aminotransferase
ASALC70_04195	COG0672	)-iron permease
ASALC70_04202	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASALC70_04203	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ASALC70_04205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASALC70_04207	COG5002	protein histidine kinase activity
ASALC70_04207	COG2198	Histidine kinase
ASALC70_04207	COG0784	Response regulator, receiver
ASALC70_04213	COG0163	prenyltransferase activity
ASALC70_04214	COG0583	DNA-binding transcription factor activity
ASALC70_04215	COG1012	belongs to the aldehyde dehydrogenase family
ASALC70_04216	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ASALC70_04217	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ASALC70_04219	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_04221	COG1028	Short-chain dehydrogenase reductase Sdr
ASALC70_04226	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ASALC70_04228	COG1024	Enoyl-CoA hydratase
ASALC70_04241	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASALC70_04245	COG2885	chlorophyll binding
ASALC70_04247	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ASALC70_04250	COG1643	Atp-dependent helicase
ASALC70_04251	COG1643	Atp-dependent helicase
ASALC70_04254	COG3220	belongs to the UPF0276 family
ASALC70_04256	COG2853	Lipoprotein
ASALC70_04258	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASALC70_04259	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ASALC70_04261	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASALC70_04266	COG5642	Protein of unknown function (DUF2384)
ASALC70_04268	COG2084	Dehydrogenase
ASALC70_04273	COG2009	succinate dehydrogenase
ASALC70_04275	COG1053	succinate dehydrogenase
ASALC70_04282	COG0045	succinate-CoA ligase (ADP-forming) activity
ASALC70_04283	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ASALC70_04287	COG1090	epimerase
ASALC70_04289	COG0326	Molecular chaperone. Has ATPase activity
ASALC70_04290	COG0326	Molecular chaperone. Has ATPase activity
ASALC70_04291	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASALC70_04292	COG2062	phosphohistidine phosphatase, SixA
ASALC70_04294	COG0708	Exodeoxyribonuclease III
ASALC70_04297	COG2267	carboxylic ester hydrolase activity
ASALC70_04300	COG3268	Saccharopine dehydrogenase
ASALC70_04303	COG1301	dicarboxylic acid transport
ASALC70_04304	COG1301	dicarboxylic acid transport
ASALC70_04306	COG0004	ammonium transporteR
ASALC70_04309	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASALC70_04310	COG2814	Major facilitator Superfamily
ASALC70_04311	COG0488	(ABC) transporter
ASALC70_04313	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASALC70_04314	COG0066	3-isopropylmalate dehydratase activity
ASALC70_04315	COG0473	3-isopropylmalate dehydrogenase activity
ASALC70_04317	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ASALC70_04320	COG0101	tRNA pseudouridine synthase activity
ASALC70_04321	COG0135	phosphoribosylanthranilate isomerase activity
ASALC70_04323	COG0159	tryptophan synthase activity
ASALC70_04324	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASALC70_04325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ASALC70_04326	COG0285	dihydrofolate synthase activity
ASALC70_04328	COG1286	toxin biosynthetic process
ASALC70_04331	COG0714	Associated with various cellular activities
ASALC70_04348	COG0789	Transcriptional regulator
ASALC70_04349	COG5001	Diguanylate cyclase
ASALC70_04349	COG4251	negative regulation of phosphorylation
ASALC70_04349	COG3706	GGDEF domain
ASALC70_04349	COG2203	Gaf domain
ASALC70_04350	COG1643	Atp-dependent helicase
ASALC70_04357	COG3228	Belongs to the MtfA family
ASALC70_04359	COG0484	heat shock protein binding
ASALC70_04360	COG0438	transferase activity, transferring glycosyl groups
ASALC70_04372	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_04375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASALC70_04376	COG1960	acyl-CoA dehydrogenase activity
ASALC70_04379	COG0784	Response regulator, receiver
ASALC70_04379	COG5002	protein histidine kinase activity
ASALC70_04381	COG0702	epimerase
ASALC70_04382	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ASALC70_04383	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ASALC70_04385	COG3416	Protein conserved in bacteria
ASALC70_04385	COG2943	transferase activity, transferring hexosyl groups
ASALC70_04386	COG3416	Protein conserved in bacteria
ASALC70_04386	COG2943	transferase activity, transferring hexosyl groups
ASALC70_04388	COG3620	sequence-specific DNA binding
ASALC70_04388	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASALC70_04388	COG0617	tRNA 3'-terminal CCA addition
ASALC70_04390	COG0039	L-malate dehydrogenase activity
ASALC70_04391	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_04394	COG2272	Belongs to the type-B carboxylesterase lipase family
ASALC70_04395	COG0271	Belongs to the BolA IbaG family
ASALC70_04396	COG1054	Belongs to the UPF0176 family
ASALC70_04400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ASALC70_04406	COG0037	tRNA processing
ASALC70_04407	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ASALC70_04409	COG1309	transcriptional regulator
ASALC70_04410	COG1335	isochorismatase
ASALC70_04411	COG0596	Alpha beta hydrolase
ASALC70_04412	COG3473	Maleate cis-trans isomerase
ASALC70_04413	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASALC70_04419	COG0683	leucine binding
ASALC70_04425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASALC70_04427	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ASALC70_04430	COG2850	peptidyl-arginine hydroxylation
ASALC70_04432	COG2915	High frequency lysogenization protein hflD homolog
ASALC70_04433	COG0482	sulfurtransferase activity
ASALC70_04435	COG0315	cyclic pyranopterin monophosphate synthase activity
ASALC70_04437	COG0314	molybdopterin synthase activity
ASALC70_04439	COG1278	Cold shock
ASALC70_04440	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ASALC70_04441	COG0542	response to heat
ASALC70_04442	COG0542	response to heat
ASALC70_04445	COG3344	reverse transcriptase
ASALC70_04449	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASALC70_04450	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASALC70_04451	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ASALC70_04452	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASALC70_04454	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ASALC70_04455	COG0492	ferredoxin-NADP+ reductase activity
ASALC70_04457	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASALC70_04458	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ASALC70_04459	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASALC70_04460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASALC70_04461	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ASALC70_04462	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASALC70_04463	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASALC70_04464	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASALC70_04464	COG1648	precorrin-2 dehydrogenase activity
ASALC70_04465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASALC70_04465	COG1648	precorrin-2 dehydrogenase activity
ASALC70_04466	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASALC70_04466	COG1648	precorrin-2 dehydrogenase activity
ASALC70_04467	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASALC70_04470	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ASALC70_04476	COG0583	DNA-binding transcription factor activity
ASALC70_04478	COG2309	aminopeptidase activity
ASALC70_04479	COG2309	aminopeptidase activity
ASALC70_04480	COG2309	aminopeptidase activity
ASALC70_04481	COG0003	Pfam Anion-transporting ATPase
ASALC70_04483	COG1966	Carbon starvation protein
ASALC70_04486	COG0322	excinuclease ABC activity
ASALC70_04487	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ASALC70_04491	COG0784	Response regulator, receiver
ASALC70_04491	COG5002	protein histidine kinase activity
ASALC70_04492	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ASALC70_04495	COG3437	response regulator, receiver