locus-tag	class	description
HML84_00005	ENOG4105E0K	tonB-dependent siderophore receptor
HML84_00065	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HML84_00070	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HML84_00110	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HML84_00115	ENOG4105C0Z	ABC transporter
HML84_00150	ENOG4105C1G	acyl-Coa dehydrogenase
HML84_00155	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HML84_00170	ENOG4105E0K	tonB-dependent siderophore receptor
HML84_00175	ENOG4105E0K	tonB-dependent siderophore receptor
HML84_00180	ENOG4105E0K	tonB-dependent siderophore receptor
HML84_00210	ENOG4105MP9	class II Aldolase
HML84_00255	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HML84_00320	ENOG4105EKQ	RNA-directed DNA polymerase
HML84_00395	ENOG4105BZU	Histidine kinase
HML84_00750	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HML84_00760	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HML84_00805	ENOG4107SBE	Glycosyl transferase (Group 1
HML84_00825	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HML84_00870	ENOG4105K64	Glycosyl transferase, family 2
HML84_00900	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HML84_00935	ENOG4105ESV	Glycosyl transferase, family 4
HML84_00945	ENOG4105ESV	Glycosyl transferase, family 4
HML84_00965	ENOG4105CY0	Metallo-Beta-Lactamase
HML84_01020	ENOG4108UWD	Iron-storage protein
HML84_01080	ENOG4105EJG	cellulose synthase
HML84_01085	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
HML84_01120	ENOG4108821	RND type efflux pump
HML84_01125	ENOG4107IFA	Lipase (EC 3.1.1.3)
HML84_01160	ENOG4105K59	histidine triad (HIT) protein
HML84_01225	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HML84_01265	ENOG4105CAT	Cytidine monophosphate kinase
HML84_01270	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HML84_01275	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HML84_01335	ENOG4105DGN	Electron transport complex
HML84_01430	ENOG4105CHM	Aminotransferase
HML84_01470	ENOG41065SU	Two-component system sensor kinase
HML84_01510	ENOG4105EGI	Transcriptional regulator
HML84_01570	ENOG4105E39	Enoyl-CoA hydratase
HML84_01715	ENOG410903C	(LipO)protein
HML84_01730	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HML84_01785	ENOG4105BZN	citrate synthase
HML84_01790	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HML84_01795	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HML84_01800	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HML84_01805	ENOG4105E33	succinate dehydrogenase
HML84_01970	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HML84_02005	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HML84_02045	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HML84_02055	ENOG4105F8C	transglutaminase domain-containing protein
HML84_02065	ENOG4105F8C	transglutaminase domain-containing protein
HML84_02160	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HML84_02165	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HML84_02280	ENOG4105BZU	Histidine kinase
HML84_02290	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HML84_02320	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HML84_02340	ENOG4105EBR	Carboxylesterase
HML84_02345	ENOG4105M85	Bola protein
HML84_02395	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HML84_02410	ENOG4105U5Y	Transcriptional regulator
HML84_02445	ENOG4105C32	Amino acid ABC transporter (Permease)
HML84_02505	ENOG4108HPG	-acetyltransferase
HML84_02535	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HML84_02565	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HML84_02585	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HML84_02595	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HML84_02600	ENOG4105C3M	thioredoxin reductase
HML84_02610	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HML84_02645	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HML84_02650	ENOG4108MN8	Membrane
HML84_02690	ENOG4105WH1	Two component transcriptional regulator luxr family
HML84_02700	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HML84_02725	ENOG4105BZU	Histidine kinase
HML84_02730	ENOG4105M3Z	response regulator
HML84_02735	ENOG4107Z5C	methylesterase
HML84_02750	ENOG4107QHF	type ii secretion system protein e
HML84_02840	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
HML84_02850	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
HML84_02885	ENOG4107R11	Transcriptional regulator
HML84_02890	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HML84_02900	ENOG4105DRR	Transcriptional regulator, GntR family
HML84_02905	ENOG4105CR4	methylisocitrate lyase
HML84_02910	ENOG4105BZN	citrate synthase
HML84_02930	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HML84_02945	ENOG4105E4C	Lytic transglycosylase catalytic
HML84_02995	ENOG4108ZG0	Ompa motb domain protein
HML84_03025	ENOG4105C2C	drug resistance transporter, Bcr CflA
HML84_03045	ENOG4108I0Y	(ABC) transporter
HML84_03050	ENOG4108UJV	acyl-CoA thioesterase i
HML84_03075	ENOG4106HNH	Acyl-transferase
HML84_03105	ENOG4107835	probably involved in intracellular septation (By similarity)
HML84_03130	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HML84_03160	ENOG4106UX7	integral membrane protein
HML84_03165	ENOG4107QX8	SPFH domain, Band 7 family protein
HML84_03205	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HML84_03280	ENOG4105RE0	Asp Glu hydantoin racemase
HML84_03305	ENOG4108VHT	MarR family transcriptional regulator
HML84_03325	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HML84_03375	ENOG4105Q9Y	Universal stress protein
HML84_03395	ENOG4107QUT	magnesium and cobalt transport protein CorA
HML84_03430	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HML84_03470	ENOG4105D3G	Pseudouridine synthase
HML84_03485	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HML84_03495	ENOG4108K0D	peptidase, M48
HML84_03515	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HML84_03560	ENOG4107RZZ	dna polymerase iii epsilon subunit
HML84_03575	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HML84_03635	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HML84_03710	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HML84_03775	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HML84_03790	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HML84_03925	ENOG4105C10	Electron transfer flavoprotein
HML84_03930	ENOG4105BZJ	Electron transfer flavoprotein
HML84_03970	ENOG4105C8Q	Methyl-accepting chemotaxis
HML84_03975	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HML84_04000	ENOG4105EYW	Ion transport protein
HML84_04015	ENOG4105WZK	nitrite reductase NADPH small subunit
HML84_04130	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HML84_04150	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HML84_04215	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HML84_04240	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HML84_04245	ENOG4108UHJ	MAF-like protein
HML84_04275	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HML84_04290	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HML84_04325	ENOG4109015	Biopolymer transport protein exbD tolR
HML84_04335	ENOG4108EC8	DNA internalization-related competence protein ComEC
HML84_04345	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HML84_04390	ENOG4108RMV	DegV Family
HML84_04405	ENOG4105CIY	formyltetrahydrofolate deformylase
HML84_04445	ENOG4105CK2	sodium dicarboxylate symporter
HML84_04460	ENOG4105CK2	sodium dicarboxylate symporter
HML84_04500	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HML84_04520	ENOG4105KMT	branched-chain amino acid
HML84_04535	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HML84_04540	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HML84_04545	ENOG4105E0A	ABC, transporter
HML84_04550	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HML84_04570	ENOG4107R4I	Periplasmic binding protein
HML84_04645	ENOG4107SQD	Transcriptional regulator, GntR family
HML84_04740	ENOG4105DHP	deoxycytidine triphosphate deaminase
HML84_04765	ENOG4105D3R	alkyl hydroperoxide reductase
HML84_04855	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
HML84_04880	ENOG4107SC1	transglycosylase
HML84_04930	ENOG4105CKT	filamentous hemagglutinin
HML84_04960	ENOG4105CKT	filamentous hemagglutinin
HML84_04965	ENOG4105D5K	Hemolysin activator protein
HML84_05030	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HML84_05040	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HML84_05065	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HML84_05070	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HML84_05095	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HML84_05140	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HML84_05155	ENOG4105CE9	30S ribosomal protein S2
HML84_05260	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HML84_05265	ENOG4105EQR	Transposase IS116 IS110 IS902
HML84_05285	ENOG4108YZA	Nitrogen regulatory protein pii
HML84_05300	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HML84_05310	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HML84_05330	ENOG4108IV0	ABC, transporter
HML84_05335	ENOG4105C0Z	ABC transporter
HML84_05405	ENOG4107RY6	amino acid
HML84_05420	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HML84_05430	ENOG4105K89	arsenate reductase
HML84_05500	ENOG4108BPE	-transporting atpase
HML84_05620	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HML84_05630	ENOG4105T95	Thiol disulfide interChange protein
HML84_05725	ENOG4105CR8	Transcriptional regulator
HML84_05780	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HML84_05785	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HML84_05930	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HML84_06045	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HML84_06075	ENOG4108RMJ	sensory transduction regulator
HML84_06100	ENOG4105EUB	pirin domain protein
HML84_06230	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HML84_06260	ENOG4107TH8	cina domain protein
HML84_06395	ENOG4105C26	Dehydrogenase
HML84_06405	ENOG4105VT3	DNA binding domain protein, excisionase family
HML84_06625	ENOG4108Z4U	Ferredoxin
HML84_06695	ENOG4107QKA	exodeoxyribonuclease V beta
HML84_06700	ENOG4107QKA	exodeoxyribonuclease V beta
HML84_06705	ENOG4107QKA	exodeoxyribonuclease V beta
HML84_06710	ENOG4107QKA	exodeoxyribonuclease V beta
HML84_06715	ENOG4107QKA	exodeoxyribonuclease V beta
HML84_06750	ENOG410689M	(LipO)protein
HML84_06800	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HML84_06815	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HML84_06870	ENOG4105C8V	SAICAR synthetase
HML84_06895	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HML84_06905	ENOG4105VFE	sira family
HML84_06915	ENOG4105CNM	Receptor
HML84_06920	ENOG4105CNM	Receptor
HML84_06925	ENOG4105CNM	Receptor
HML84_06990	ENOG4108XDN	Transcriptional regulator
HML84_07005	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HML84_07045	ENOG4105M8F	Biopolymer transport protein exbD tolR
HML84_07065	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HML84_07070	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HML84_07075	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HML84_07080	ENOG4105CDY	transcriptional regulatory protein
HML84_07085	ENOG4105C9M	aspartyl-trna synthetase
HML84_07140	ENOG4105MA0	exported protein
HML84_07150	ENOG4105MA0	exported protein
HML84_07180	ENOG4105CSU	acyl-Coa dehydrogenase
HML84_07220	ENOG4105C1J	atp-dependent rna helicase
HML84_07285	ENOG4105C8Y	Acetylornithine aminotransferase
HML84_07315	ENOG4107EXC	regulatoR
HML84_07335	ENOG4105C7K	acetolactate synthase
HML84_07415	ENOG4105QPS	Monooxygenase
HML84_07420	ENOG4105QPS	Monooxygenase
HML84_07470	ENOG4108V8F	Transcriptional regulator, MarR family
HML84_07475	ENOG4105EE5	Membrane protein terC
HML84_07500	ENOG4107QM5	aconitate hydratase
HML84_07570	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HML84_07735	ENOG4105EWT	decarboxylase family
HML84_07835	ENOG4105EQ2	LysR family Transcriptional regulator
HML84_07850	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HML84_07900	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HML84_07935	ENOG4105VDW	Csbd family
HML84_07985	ENOG4105BZE	flagellar hook protein, FlgE
HML84_07990	ENOG4105W00	Flagellar hook capping protein
HML84_08000	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HML84_08055	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HML84_08095	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HML84_08175	ENOG4105CG5	Glycosyl transferase (Group 1
HML84_08235	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HML84_08240	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HML84_08290	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HML84_08325	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HML84_08330	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HML84_08395	ENOG4107MKT	Stringent starvation protein a
HML84_08400	ENOG4105EIX	cytochrome c1
HML84_08415	ENOG4108UJD	30S ribosomal protein S9
HML84_08460	ENOG4105DRR	Transcriptional regulator, GntR family
HML84_08480	ENOG4105C0Z	ABC transporter
HML84_08500	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HML84_08515	ENOG4105DHZ	alpha beta
HML84_08535	ENOG4107QNR	UPF0135 protein
HML84_08560	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HML84_08580	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HML84_08595	ENOG4108IUZ	ABC transporter
HML84_08605	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HML84_08615	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HML84_08625	ENOG4105CJW	magnesium transporter
HML84_08740	ENOG4105VQ7	Rod shape-determining protein MreD
HML84_08745	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HML84_08755	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HML84_08830	ENOG4108ZZF	transport protein (ExbD)
HML84_08870	ENOG4108KPJ	rna polymerase sigma factor
HML84_08910	ENOG4105D06	uba thif-type nad fad binding protein
HML84_08930	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HML84_09040	ENOG4105D7W	serine acetyltransferase
HML84_09065	ENOG4108JPW	Aminotransferase
HML84_09070	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HML84_09195	ENOG4105CHR	reductase
HML84_09325	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HML84_09400	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HML84_09435	ENOG4105CEY	Amp-dependent synthetase and ligase
HML84_09440	ENOG4105CEY	Amp-dependent synthetase and ligase
HML84_09480	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HML84_09565	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HML84_09595	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HML84_09615	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HML84_09805	ENOG4105D3R	alkyl hydroperoxide reductase
HML84_09815	ENOG4108ZT0	50S ribosomal protein l17
HML84_09820	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HML84_09830	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HML84_09835	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HML84_09840	ENOG41067V7	50S ribosomal protein L36
HML84_09850	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HML84_09865	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HML84_09880	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HML84_09890	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HML84_09895	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HML84_09900	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HML84_09905	ENOG41083MP	50s ribosomal protein l29
HML84_09925	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HML84_09955	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HML84_09965	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HML84_09990	ENOG4108VZM	50s ribosomal protein L10
HML84_09995	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HML84_10005	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HML84_10020	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HML84_10055	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HML84_10115	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HML84_10145	ENOG4108YXA	Membrane
HML84_10265	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HML84_10280	ENOG4105CW7	secretion protein, HlyD family
HML84_10295	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HML84_10305	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HML84_10335	ENOG4107EJC	Preprotein translocase subunit SecG
HML84_10345	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HML84_10360	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HML84_10415	ENOG41090R7	Ferric uptake
HML84_10420	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HML84_10435	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HML84_10465	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HML84_10485	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HML84_10570	ENOG4105DJ2	Major Facilitator Superfamily
HML84_10575	ENOG4105DJ2	Major Facilitator Superfamily
HML84_10740	ENOG4108V1U	phospholipid-binding protein
HML84_10745	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HML84_10785	ENOG41090A4	Pterin carbinolamine dehydratase
HML84_10845	ENOG4105D49	3-dehydroquinate synthase
HML84_10850	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HML84_10890	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HML84_10925	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HML84_10935	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HML84_10955	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HML84_10970	ENOG4107XM9	(LipO)protein
HML84_11020	ENOG4105C5F	glutamine synthetase
HML84_11025	ENOG4105VFE	sira family
HML84_11040	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HML84_11080	ENOG41063SB	peptidase
HML84_11090	ENOG4105PXI	polysaccharide deacetylase
HML84_11115	ENOG4108UPT	UPF0178 protein
HML84_11145	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HML84_11155	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HML84_11190	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HML84_11335	ENOG4105E02	MotA TolQ exbB proton channel
HML84_11405	ENOG4105DR5	peptidase
HML84_11435	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HML84_11445	ENOG4107R9N	ABC transporter
HML84_11475	ENOG4105SKE	transcriptional Regulator LysR family
HML84_11520	ENOG4105C0Z	ABC transporter
HML84_11545	ENOG4105KVH	Transcriptional regulator
HML84_11555	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HML84_11620	ENOG4105CF7	AraC family transcriptional regulator
HML84_11675	ENOG4105EEF	Alkane 1-monooxygenase
HML84_11690	ENOG4105E0K	tonB-dependent siderophore receptor
HML84_11700	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HML84_11705	ENOG4105K5B	UPF0225 protein
HML84_11710	ENOG4105K5B	UPF0225 protein
HML84_11720	ENOG4107MHI	Transcriptional regulator, MarR family
HML84_11750	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HML84_11775	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HML84_11840	ENOG4105F95	Monooxygenase
HML84_11930	ENOG4108YZT	Adenosylcobinamide kinase
HML84_11960	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HML84_12000	ENOG4105EKQ	RNA-directed DNA polymerase
HML84_12030	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HML84_12175	ENOG4105EJ9	Membrane
HML84_12240	ENOG4105BZU	Histidine kinase
HML84_12295	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HML84_12300	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HML84_12320	ENOG4105VEQ	Cold shock protein
HML84_12350	ENOG4105DSF	transport protein
HML84_12375	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HML84_12410	ENOG4105ER2	Ompa motb domain protein
HML84_12490	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HML84_12495	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HML84_12545	ENOG4105CF7	AraC family transcriptional regulator
HML84_12590	ENOG4108S3W	Anti-feci sigma factor, fecr
HML84_12800	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HML84_12825	ENOG4105E66	phosphoriboisomerase A
HML84_12865	ENOG4105DUM	transcriptional regulator, lysR family
HML84_12870	ENOG4105CI2	imidazolone-5-propionate hydrolase
HML84_12875	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HML84_12900	ENOG4105BZA	Phosphoglycerate kinase
HML84_12925	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HML84_12965	ENOG4105HFT	AraC family transcriptional regulator
HML84_13060	ENOG4105CAK	Cell division ATP-binding protein ftsE
HML84_13065	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HML84_13130	ENOG4105DWV	Homoserine O-trans-acetylase
HML84_13135	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HML84_13140	ENOG4105CSA	Coproporphyrinogen iii oxidase
HML84_13290	ENOG4108KEZ	Dehydrogenase
HML84_13310	ENOG4105D7T	ABC transporter
HML84_13320	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HML84_13345	ENOG4107QKV	phosphomannomutase
HML84_13350	ENOG4107QKV	phosphomannomutase
HML84_13355	ENOG4105CAS	nag kinase
HML84_13440	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HML84_13450	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
HML84_13460	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HML84_13490	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HML84_13580	ENOG4105E2X	shikimate dehydrogenase
HML84_13615	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HML84_13655	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
HML84_13740	ENOG4105II7	pyrroline-5-carboxylate reductase
HML84_13755	ENOG4105CZX	twitching motility protein
HML84_13760	ENOG4108Z9K	Osmotically inducible protein
HML84_13780	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HML84_13805	ENOG4105PE1	Receptor
HML84_13810	ENOG4105PE1	Receptor
HML84_13835	ENOG4105DHQ	Histidine kinase
HML84_13855	ENOG4107QX9	Thiol disulfide interChange protein
HML84_13890	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HML84_13970	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HML84_13980	ENOG4107QX8	SPFH domain, Band 7 family protein
HML84_14065	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HML84_14105	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HML84_14120	ENOG4105EQK	-acetyltransferase
HML84_14130	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HML84_14150	ENOG4105C0Z	ABC transporter
HML84_14155	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HML84_14200	ENOG4108SAU	DNA-binding protein H-ns
HML84_14225	ENOG4105VG0	50S ribosomal protein l34
HML84_14230	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HML84_14260	ENOG4105C9Q	fumarate hydratase class II
HML84_14275	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HML84_14315	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HML84_14370	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HML84_14375	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HML84_14395	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HML84_14435	ENOG4105EMU	Dehydrogenase
HML84_14455	ENOG4105CP9	extracellular ligand-binding receptor
HML84_14520	ENOG4108SGK	Tetr family transcriptional regulator
HML84_14535	ENOG4105CSU	acyl-Coa dehydrogenase
HML84_14580	ENOG4105CH5	extracellular solute-binding protein, family 7
HML84_14585	ENOG4105NAU	thioesterase Superfamily protein
HML84_14615	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HML84_14620	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HML84_14625	ENOG4105KBH	arsR family transcriptional regulator
HML84_14680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HML84_14695	ENOG4105VCQ	rubredoxin
HML84_14780	ENOG4108RU0	short-chain dehydrogenase reductase
HML84_14830	ENOG4105CH6	catalase
HML84_14865	ENOG4105EV8	ectoine hydroxylase
HML84_14875	ENOG4105C1G	acyl-Coa dehydrogenase
HML84_14940	ENOG4105W4C	monovalent cation H antiporter subunit F
HML84_14945	ENOG4105KJM	monovalent cation h antiporter subunit g
HML84_14960	ENOG4106RE7	Cytochrome
HML84_14965	ENOG4108Z33	Thiol disulfide Interchange Protein
HML84_14995	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HML84_15175	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HML84_15380	ENOG4105MPD	Cytochrome
HML84_15415	ENOG4105CHR	reductase
HML84_15430	ENOG4105W0Z	cytoplasmic protein
HML84_15455	ENOG4105F1S	paraquat-inducible protein a
HML84_15565	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HML84_15605	ENOG4108KSA	LysR family transcriptional regulator
HML84_15610	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HML84_15620	ENOG41077A9	carbonic anhydrase
HML84_15635	ENOG4105E3B	Multicopper oxidase
HML84_15645	ENOG4105E3B	Multicopper oxidase
HML84_15670	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HML84_15710	ENOG4108YZA	Nitrogen regulatory protein pii
HML84_15830	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HML84_15870	ENOG4105CNM	Receptor
HML84_15935	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HML84_15960	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HML84_15975	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HML84_16050	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HML84_16055	ENOG4105K63	Thioredoxin
HML84_16090	ENOG4108RRZ	Transcription elongation factor GreB
HML84_16120	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HML84_16125	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
HML84_16155	ENOG4105M3Z	response regulator
HML84_16195	ENOG4105CH7	arginosuccinase
HML84_16330	ENOG4108SHN	Glycosyl transferase, family 2
HML84_16375	ENOG4105D1S	lipid A biosynthesis
HML84_16420	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HML84_16455	ENOG4107QMH	DNA methylase
HML84_16485	ENOG4105WP7	tRNA pseudouridine synthase C
HML84_16490	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HML84_16555	ENOG4108S3W	Anti-feci sigma factor, fecr
HML84_16605	ENOG4105CNM	Receptor
HML84_16625	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HML84_16635	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HML84_16645	ENOG4105IU3	Glutathione S-transferase
HML84_16680	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HML84_16730	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HML84_16785	ENOG4107SQI	penicillin amidase
HML84_16800	ENOG41081E8	Alpha beta hydrolase
HML84_16810	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HML84_16835	ENOG4105EAC	phosphoserine phosphatase
HML84_16865	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HML84_16900	ENOG4105K8N	protein family UPF0079, ATPase
HML84_16905	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HML84_16925	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HML84_16960	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HML84_16965	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HML84_16985	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HML84_17040	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HML84_17045	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HML84_17080	ENOG4105C8Q	Methyl-accepting chemotaxis
HML84_17115	ENOG4105EMN	RNA polymerase sigma factor
HML84_17155	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HML84_17165	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HML84_17175	ENOG4105BZU	Histidine kinase
HML84_17190	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HML84_17195	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HML84_17200	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HML84_17265	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HML84_17275	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HML84_17290	ENOG41082AG	Plasmid maintenance system antidote protein
HML84_17350	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HML84_17375	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HML84_17380	ENOG4105CMI	transporter
HML84_17395	ENOG4107EFR	Flavocytochrome c
HML84_17400	ENOG4107EFR	Flavocytochrome c
HML84_17435	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HML84_17445	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HML84_17455	ENOG4105CFP	Peptidase U32
HML84_17590	ENOG4108ZJI	phenylacetic acid degradation protein
HML84_17650	ENOG4108ZT1	Transcriptional regulator
HML84_17665	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HML84_17685	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HML84_17690	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HML84_17705	ENOG4105RE0	Asp Glu hydantoin racemase
HML84_17755	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HML84_17760	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HML84_17770	ENOG4108ZAI	phosphatidylglycerophosphatase a
HML84_17775	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HML84_17780	ENOG4105CTB	Polyprenyl synthetase
HML84_17795	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HML84_17840	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HML84_17855	ENOG4108V8F	Transcriptional regulator, MarR family
HML84_17865	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HML84_17905	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HML84_17915	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HML84_18030	ENOG4105HDD	phospholipase
HML84_18035	ENOG4105W49	UPF0434 protein
HML84_18090	ENOG4105D82	Glutamate dehydrogenase
HML84_18100	ENOG4105KPV	Transcriptional regulator
HML84_18160	ENOG4105EA8	2-Nitropropane dioxygenase
HML84_18210	ENOG4105E33	succinate dehydrogenase
HML84_18255	ENOG4105VCC	30S ribosomal protein S21
HML84_18265	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HML84_18280	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HML84_18295	ENOG4105EA8	2-Nitropropane dioxygenase
HML84_18335	ENOG4105NWN	ApaG protein
HML84_18360	ENOG4105EHM	Aminoglycoside phosphotransferase
HML84_18365	ENOG4105EHM	Aminoglycoside phosphotransferase
HML84_18370	ENOG4105EHM	Aminoglycoside phosphotransferase
HML84_18415	ENOG4105CCU	oxidase (Subunit III)
HML84_18435	ENOG4108UYB	regulatoR
HML84_18460	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HML84_18490	ENOG4108UKZ	OsmC family
HML84_18500	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
HML84_18520	ENOG4105BZU	Histidine kinase
HML84_18555	ENOG4105C12	Phosphoribosylglycinamide synthetase
HML84_18560	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HML84_18565	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HML84_18605	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HML84_18685	ENOG4105EIF	outer membrane protein W
HML84_18695	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HML84_18700	ENOG4105C2W	permease
HML84_18770	ENOG4105C0Z	ABC transporter
HML84_18810	ENOG4105DFU	Cell wall formation (By similarity)
HML84_18840	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
HML84_18850	ENOG4108SF5	RNA Polymerase
HML84_18945	ENOG4107TV1	YD repeat protein
HML84_18965	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HML84_19025	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HML84_19060	ENOG4107S76	domain protein
HML84_19095	ENOG4105ECW	sulfate abc transporter
HML84_19180	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HML84_19260	ENOG4108V0P	LemA family
HML84_19345	ENOG4105XDF	Protein of unknown function (DUF1272)
HML84_19350	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HML84_19470	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HML84_19485	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HML84_19490	ENOG4105VG1	fes assembly suf system protein
HML84_19495	ENOG4108Z4V	iron-sulfur cluster assembly
HML84_19505	ENOG4105JRK	feS assembly protein SufD
HML84_19525	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HML84_19580	ENOG4107RNH	Outer membrane receptor FepA
HML84_19860	ENOG4105KVH	Transcriptional regulator
HML84_19915	ENOG4105VUF	Transcriptional regulator
HML84_19920	ENOG4107RSM	transcriptional regulator
HML84_19985	ENOG4105W08	virulence gene repressor rsal
HML84_20060	ENOG4107SCA	Formamidase (EC 3.5.1.49)
HML84_20100	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HML84_20150	ENOG4105C26	Dehydrogenase
HML84_20315	ENOG4105EGD	dinuclear metal center protein, YbgI family
HML84_20335	ENOG4105D78	K07001 NTE family protein
HML84_20375	ENOG4105CKT	filamentous hemagglutinin
HML84_20380	ENOG4105CKT	filamentous hemagglutinin
HML84_20390	ENOG4105D5K	Hemolysin activator protein
HML84_20450	ENOG4105T95	Thiol disulfide interChange protein
HML84_20460	ENOG4105D6E	homoserine dehydrogenase
HML84_20475	ENOG4105C94	Transporter
HML84_20635	ENOG4105D5T	phosphonate abc transporter
HML84_20640	ENOG4107T9Q	phosphonate abc transporter
HML84_20710	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HML84_20830	ENOG4106943	Heat shock protein
HML84_20835	ENOG4105WKW	Pfam:DUF1458
HML84_20925	ENOG4105DND	Transcriptional regulator
HML84_21075	ENOG4105M03	Domain of unknown function (DUF955)
HML84_21130	ENOG4105CRK	lysyL-tRNA synthetase
HML84_21215	ENOG4105C3F	Signal peptidase i
HML84_21235	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HML84_21250	ENOG4105BZU	Histidine kinase
HML84_21285	ENOG4105DXN	mazG family
HML84_21305	ENOG4105W1Y	Transcriptional regulator
HML84_21310	ENOG4105D5G	Transposase
HML84_21320	ENOG4105EKQ	RNA-directed DNA polymerase
HML84_21340	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HML84_21345	ENOG4105DA4	cytochrome c-type biogenesis protein
HML84_21350	ENOG4105DA4	cytochrome c-type biogenesis protein
HML84_21360	ENOG4105KWW	Biogenesis protein
HML84_21370	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HML84_21435	ENOG4105DZ2	Transcriptional regulator
HML84_21455	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HML84_21460	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HML84_21465	ENOG41060IM	Heme exporter protein
HML84_21575	ENOG4105NXH	GreA GreB family elongation factor
HML84_21610	ENOG4105F8J	Adenylate Guanylate cyclase
HML84_21615	ENOG41069NU	Nitroreductase
HML84_21650	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HML84_21655	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HML84_21665	ENOG4105CPC	Aldo Keto reductase
HML84_21710	ENOG4105UYK	outer membrane protein a
HML84_21735	ENOG4105C32	Amino acid ABC transporter (Permease)
HML84_21780	ENOG4105C1G	acyl-Coa dehydrogenase
HML84_21795	ENOG4105E39	Enoyl-CoA hydratase
HML84_21815	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HML84_21950	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HML84_21955	ENOG4107SM7	Transcriptional regulator
HML84_21970	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HML84_21980	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HML84_22025	ENOG4105C0Z	ABC transporter